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See detailPostoperative care in endoscopic sinus surgery: a critical review.
Eloy, Philippe; Andrews, Peter; POIRRIER, Anne-Lise ULg

in Current Opinion in Otolaryngology & Head & Neck Surgery (2017), 25(1), 35-42

PURPOSE OF REVIEW: Chronic rhinosinusitis with and without nasal polyps is a common disease affecting people all over the world. Functional endoscopic sinus surgery (FESS) has become the gold standard ... [more ▼]

PURPOSE OF REVIEW: Chronic rhinosinusitis with and without nasal polyps is a common disease affecting people all over the world. Functional endoscopic sinus surgery (FESS) has become the gold standard treatment for medically refractive disease. Postoperative care is recommended by international leaders as an important part of the patient's management. This article is a critical review and discussion focusing on postoperative care, which is based on expert opinion, clinical studies, randomized controlled trials and meta-analysis studies. RECENT FINDINGS: Postoperative care including nasal rinsing, topical corticosteroids, antibiotics and avoidance of nasal packing are unanimously considered to be the cornerstone of best practice following FESS. However, the effectiveness of in-office nasal debridement is still under debate. SUMMARY: There is a lack of consensus regarding the necessity of performing in-office nasal debridement and the majority of clinicians carry out their postoperative care according to experience and their own preference. This is often determined by the extent of surgery performed, the severity of the postoperative inflammation, as well as being dependent on the patient's discomfort, the time constraints associated with postoperative care and the costs associated with additional appointments. Ideally, nasal debridement should be performed by the operating surgeon under endoscopic control both gently and atraumatically. [less ▲]

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See detailPsychopathologie de l'homme en situation - deuxième édition avec préface de l'auteur
Englebert, Jérôme ULg

Book published by Hermann - 2ème éd. (2017)

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See detailThe somatotrope Growth Hormone-Releasing Hormone/Growth Hormone/Insulin-like Growth Factor 1 axis in immunoregulation and immunosenescence
Bodart, Gwennaëlle ULg; Farhat, Khalil; RENARD, Jeanne de Chantal ULg et al

in Savino, Wilson; Guaraldi, Federica (Eds.) Endocrine Immunology (2017)

Most scientific reports debate the thymotropic and immuno-stimulating properties of the somato- trope growth hormone-releasing hormone (GHRH)/growth hormone (GH)/insulin-like growth factor (IGF)-1 axis ... [more ▼]

Most scientific reports debate the thymotropic and immuno-stimulating properties of the somato- trope growth hormone-releasing hormone (GHRH)/growth hormone (GH)/insulin-like growth factor (IGF)-1 axis, but there is still some disagreement about the physiological role of this axis in basal conditions. Moreover, some authors have hypothesized that the physiological role of the somato- trope axis only appears in stressful conditions (such as sepsis or infective and inflammatory diseases). This chapter will provide an extended overview of the expression of the components (signals and receptors) of the somatotrope axis and their properties on cells of the innate and adaptive immune system. It will also summarize some clinical studies suggesting a benefit for a short-term GH treat- ment in acute immunodeficiencies, and the importance of GH supplementation in adult GH defi- ciency. A new transgenic mouse model, the hypothalamic GHRH-deficient (Ghrh–/–) mouse, which exhibits a severe deficiency of the somatotrope axis, will be presented since it will be of great help in further deciphering the regulation by the GHRH/GH/IGF-1 axis on both immune development and function. Finally, we will discuss the implication of aging-related somatopause in relation to the general context of Immunosenescence. [less ▲]

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See detailFish habitat selection in a large hydropeaking river: Strong individual and temporal variations revealed by telemetry
Capra, Hervé; Plichard, Laura; Bergé, Julien et al

in Science of the Total Environment (2017), 578

Modeling individual fish habitat selection in highly variable environments such as hydropeaking rivers is required for guiding efficient management decisions. We analyzed fish microhabitat selection in ... [more ▼]

Modeling individual fish habitat selection in highly variable environments such as hydropeaking rivers is required for guiding efficient management decisions. We analyzed fish microhabitat selection in the heterogeneous hydraulic and thermal conditions (modeled in two-dimensions) of a reach of the large hydropeaking Rhône River locally warmed by the cooling system of a nuclear power plant. We used modern fixed acoustic telemetry techniques to survey 18 fish individuals (five barbels, six catfishes, seven chubs) signaling their position every 3 s over a three-month period. Fish habitat selection depended on combinations of current microhabitat hydraulics (e.g. velocity, depth), past microhabitat hydraulics (e.g. dewatering risk or maximum velocities during the past 15 days) and to a lesser extent substrate and temperature. Mixed-effects habitat selection models indicated that individual effects were often stronger than specific effects. In the Rhône, fish individuals appear to memorize spatial and temporal environmental changes and to adopt a “least constraining” habitat selection. Avoiding fast-flowing midstream habitats, fish generally live along the banks in areas where the dewatering risk is high. When discharge decreases, however, they select higher velocities but avoid both dewatering areas and very fast-flowing midstream habitats. Although consistent with the available knowledge on static fish habitat selection, our quantitative results demonstrate temporal variations in habitat selection, depending on individual behavior and environmental history. Their generality could be further tested using comparative experiments in different environmental configurations. [less ▲]

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See detailGrowth velocity of preterm infants - analysis and recommendations
Fenton, Tanis; Hoyos, Angela; Groh-Wargo, Sharon et al

Conference (2017)

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See detailGrowth velocity of preterm infants - analysis and recommendations
Fenton, Tanis; Hoyaos, Angela; Groh-Wargo, Sharon et al

Conference (2017)

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See detailL. Volusius Maecianus, De assis distributione
Rochette, Bruno ULg

in Mantovani, Dario; Wibier, Matthijs (Eds.) History and Geography of Late Antique Legal Culture (2017)

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See detailThe Characteristics of al-Maqrīzī's Handwriting
Bauden, Frédéric ULg

in Bauden, Frédéric; Franssen, Elise (Eds.) "In the Author's Hand": Holograph and Authorial Manuscripts in the Islamic Handwritten Tradition (2017)

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See detail"In the Author's Hand": Holograph and Authorial Manuscripts in the Islamic Handwritten Tradition
Bauden, Frédéric ULg; Franssen, Elise ULg

Book published by Brill Academic Publishers (2017)

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See detailThe Cross-Cultural Legacy: Critical and Creative Writings in Memory of Hena Maes-Jelinek
Collier, Gordon; Davis, Geoffrey; Delrez, Marc ULg et al

Book published by Brill/Rodopi (2017)

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See detailA vertebrate specific and essential role for sp7/osterix in osteogenesis revealed by gene knock-out in the teleost medaka.
Yu, T; Graf, M; Renn, Jörg ULg et al

in Development (2017), 144(2), 265-271

Sp7/osterix (osx) encodes a zinc-finger transcription factor that controls osteoblast differentiation in mammals. Although identified in all vertebrate lineages, its role in non-mammalian bone formation ... [more ▼]

Sp7/osterix (osx) encodes a zinc-finger transcription factor that controls osteoblast differentiation in mammals. Although identified in all vertebrate lineages, its role in non-mammalian bone formation remains elusive. Here we show that an osx mutation in medaka results in severe bone defects and larval lethality. Pre-osteoblasts fail to differentiate leading to severe intramembranous and perichondral ossification defects. The notochord sheath mineralizes normally supporting the idea of an osteoblast-independent mechanism for teleost vertebral centra formation. This study establishes a key role for Sp7/Osx for bone formation also in a non-mammalian species, and reveals conserved and non-conserved features in vertebrate bone formation. [less ▲]

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See detailSchizophrénie et perspective en première personne : Essai de psychopathologie phénoménologique
Valentiny, Caroline; Englebert, Jérôme ULg

Book published by De Boeck (2017)

Comment rencontrer l’homme schizophrène dans sa singularité, dans la richesse et les difficultés de son expérience ? Comment partager l’indicible de la rupture psychotique ? Comment dépasser les ... [more ▼]

Comment rencontrer l’homme schizophrène dans sa singularité, dans la richesse et les difficultés de son expérience ? Comment partager l’indicible de la rupture psychotique ? Comment dépasser les catégorisations symptomatiques réduisant, selon une perspective en troisième personne, l’homme à sa maladie ? Les auteurs proposent une approche contemporaine et inédite de la schizophrénie. Ils s’inspirent d’un outil, l’échelle EASE, qui permet, selon une perspective en première personne, une exploration guidée de la (des) subjectivité(s) schizophrénique(s). L’échelle pose des balises dans l’investigation d’expériences liées aux troubles du soi. Elle permet de percevoir différemment la maladie, de l’intérieur, offrant ainsi une alternative rigoureuse aux approches a-subjectives des DSM-IV et 5. Située en amont de tout a priori théorique, la voie de la psychopathologie phénoménologique est une perspective originale, susceptible de nouer des dialogues féconds tant avec la psychanalyse qu’avec les sciences cognitives. Le choix d’une approche phénoménologique s’ancre dans une volonté de laisser la place à l’étonnement, de ne pas pré-penser, ou le moins possible, le recueil d’expériences. Les explorations des phénomènes décrits par les patients se nourrissent de la tradition de la psychopathologie phénoménologique (Blankenburg, Minkowski, Binswanger, Tatossian) et de ses apports contemporains (Stanghellini, Sass, Parnas, Fuchs) tout en laissant au phénomène clinique la primauté. Après une analyse approfondie du discours des patients, l’ouvrage explore l’hypothèse proposée par Louis Sass selon laquelle la folie pourrait dériver d’une intensification plutôt que d’un affaiblissement de la conscience. Les phénomènes d’hyper-réflexivité, particulièrement saillants dans les descriptions, semblent constituer des moments centraux dans leur rapport au monde. Ils se plaignent notamment d’une exacerbation de la pensée, de la recherche de sens, de l’intensité de la réflexion au détriment de la capacité d’abandon naturelle et antéprédicative au monde. Ce que les personnes schizophrènes ont à nous dire de leur expérience subjective, si l’on prend la peine de la creuser avec elles et malgré la rudesse de leur vécu, s’avère, au final, étonnant. [less ▲]

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See detailSartre, le XXe siècle
Cormann, Grégory ULg

in Médium (2017), 50

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See detailA new, challenging benchmark for nonlinear system identification
Tiso, Paolo; Noël, Jean-Philippe ULg

in Mechanical Systems & Signal Processing (2017), 84

The progress accomplished during the past decade in nonlinear system identi fication in structural dynamics is considerable. The objective of the present paper is to consolidate this progress by ... [more ▼]

The progress accomplished during the past decade in nonlinear system identi fication in structural dynamics is considerable. The objective of the present paper is to consolidate this progress by challenging the community through a new benchmark structure exhibiting complex nonlinear dynamics. The proposed structure consists of two o ffset cantilevered beams connected by a highly flexible element. For increasing forcing amplitudes, the system sequentially features linear behaviour, localised nonlinearity associated with the buckling of the connecting element, and distributed nonlinearity resulting from large elastic deformations across the structure. A finite element-based code with time integration capabilities is made available at http://sem.org/TDIV-Nonlin.asp. This code permits the numerical simulation of the benchmark dynamics in response to arbitrary excitation signals. [less ▲]

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See detailA nonlinear state-space approach to hysteresis identification
Noël, Jean-Philippe ULg; Esfahani, Alireza; Kerschen, Gaëtan ULg et al

in Mechanical Systems & Signal Processing (2017), 84

Most studies tackling hysteresis identification in the technical literature follow white-box approaches, i.e. they rely on the assumption that measured data obey a specific hysteretic model. Such an ... [more ▼]

Most studies tackling hysteresis identification in the technical literature follow white-box approaches, i.e. they rely on the assumption that measured data obey a specific hysteretic model. Such an assumption may be a hard requirement to handle in real applications, since hysteresis is a highly individualistic nonlinear behaviour. The present paper adopts a black-box approach based on nonlinear state-space models to identify hysteresis dynamics. This approach is shown to provide a general framework to hysteresis identification, featuring flexibility and parsimony of representation. Nonlinear model terms are constructed as a multivariate polynomial in the state variables, and parameter estimation is performed by minimising weighted least-squares cost functions. Technical issues, including the selection of the model order and the polynomial degree, are discussed, and model validation is achieved in both broadband and sine conditions. The study is carried out numerically by exploiting synthetic data generated via the Bouc-Wen equations. [less ▲]

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See detailEffective components of interventions in juvenile justice facilities: How to take care of delinquent youths?
Mathys, Cécile ULg

in Children and Youth Services Review (2017), 73

Therapeutic interventions support change in delinquent youths rather than rely on surveillance and deterrence. This article describes successful and concrete components for therapeutic interventions in ... [more ▼]

Therapeutic interventions support change in delinquent youths rather than rely on surveillance and deterrence. This article describes successful and concrete components for therapeutic interventions in juvenile justice facilities. The effectiveness of remedial measures to best address the sources of youths' delinquent behaviors and the performance of juvenile justice system are discussed first, and then two theoretical frameworks of rehabilitative models are described that are commonly used with delinquent youths. Finally, specific recommendations for enhancing treatment in juvenile justice facilities with regard to the content of interventions, social climate, and youth motivation to engage in treatment are described and explained in a way intended to help caregivers and practitioners, supervisors of juvenile justice facilities, and policy makers improve the daily life of youths placed in this kind of environment. [less ▲]

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See detailSilica or Coal ? Design and Implementation of Dust Prevention in the Collieries in Western Economies, ca. 1930-1980
Geerkens, Eric ULg

in Rosental, Paul-André (Ed.) Silicosis. A World History (2017)

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See detailL’ÉVALUATION DES POLITIQUES PUBLIQUES DANS LE CHAMP DE LA COOPÉRATION AU DÉVELOPPEMENT BELGE : LE CAS DU SERVICE DE L’ÉVALUATION SPÉCIALE
Contor, Justine ULg

in Pyramides : Revue du Laboratoire d'Etudes et de Recherches en Administration Publique (2017)

Cette contribution s’intéresse à l'évolution institutionnelle de l'évaluation au sein de la coopération belge au développement et plus spécifiquement à notre cas d’étude : le Service de l’Evaluation ... [more ▼]

Cette contribution s’intéresse à l'évolution institutionnelle de l'évaluation au sein de la coopération belge au développement et plus spécifiquement à notre cas d’étude : le Service de l’Evaluation Spéciale de la coopération belge au développement (SES). Nous présenterons dans ce document les raisons de la création de ce service au début des années 2000. En effet, le SES, avec d’autres acteurs, est le résultat d’une grande réforme de la coopération issue d’une lourde crise. Nous reviendrons sur son mandat, sur ses spécificités organisationnelles (ressources financières et humaines) ainsi que son cadre de référence normatif. La question de la culture évaluative sera questionnée, ainsi que son lien avec l’émergence du New Public Management dans la politique de coopération au développement. Enfin, nous questionnerons la légitimité d’une structure telle que le SES au regard d’un cadrage théorique mixte (Scott, 1995 ; Suchmann, 1995) et de la théorie des parties prenantes. [less ▲]

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See detailEvaluation d'un itinéraire clinique pour collectomie gauche en chirurgie abdominale
Mattart, Laurine; Stevens, Marie; Magis, David ULg et al

in Revue Médicale de Liège (2017), 72(1), 45-50

Fin 2008, l’itinéraire clinique (IC) «colectomie gauche» a été mis en place au sein de la Clinique Saint-Joseph (CHC) de Liège. Une série de 213 patients présentant une pathologie bénigne ou maligne ... [more ▼]

Fin 2008, l’itinéraire clinique (IC) «colectomie gauche» a été mis en place au sein de la Clinique Saint-Joseph (CHC) de Liège. Une série de 213 patients présentant une pathologie bénigne ou maligne nécessitant une résection du côlon gauche par laparoscopie a été incluse dans cet IC entre 2009 et 2015. Nous nous sommes intéressés à l’observance du protocole de l’IC ainsi qu’aux taux de complications et de ré-hospitalisations dans les 30 jours post-opératoires. Nous avons constaté, après comparaison avec un groupe témoin historique, que l’adhésion au protocole IC a été d’emblée excellente (> 80 %) tout au long de la durée de l’étude. Il n’y a pas eu de modification du taux de ré-hospitalisations et le taux de lâchage de suture a été réduit. Bien que la diminution de la durée de séjour n’était pas l’objectif premier lors de la mise en place de cet IC, elle s’est significativement réduite passant, en moyenne, de 8 à 4 jours. En conclusion, l’introduction d’un IC, pour autant qu’il soit bien préparé et rassemble dans le même objectif l’ensemble des acteurs de soins, est directement bénéfique pour le patient et la qualité de sa prise en charge. [less ▲]

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