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See detailIntroduction. L’(in)sécurité : entre représentations et perceptions des concepts
Grandjean, Geoffrey ULg; Wintgens, Sophie ULg; Vanhaeren, Stéphanie ULg

in Wintgens, Sophie; Grandjean, Geoffrey; Vanhaeren, Stéphanie (Eds.) L’insécurité en question. Définition, enjeux et perspectives (in press)

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See detailL'insécurité en question. Définition, enjeux et perspectives
Wintgens, Sophie ULg; Grandjean, Geoffrey ULg; Vanhaeren, Stéphanie ULg

Book published by Presses Universitaires de Liège (in press)

Ces dernières années, l’analyse et les pratiques de la sécurité et de l’insécurité ont fortement évolué sous l’influence de plusieurs facteurs fortement imbriqués, tels que le déclin de la souveraineté ... [more ▼]

Ces dernières années, l’analyse et les pratiques de la sécurité et de l’insécurité ont fortement évolué sous l’influence de plusieurs facteurs fortement imbriqués, tels que le déclin de la souveraineté nationale, l’accroissement de l’intensité des interactions transnationales ou encore l’éclatement conflictuel sous-tendu par des dynamiques identitaires. Ces constats et les représentations qui leur sont associées ont enjoint un réexamen de la manière dont la sécurité et l’insécurité se pensent et se pratiquent. Inscrit au cœur de ce double questionnement contemporain, cet ouvrage met en question la définition et les enjeux liés aux dynamiques actuelles d’(in)sécurité tout en proposant de nouvelles perspectives. Privilégiant les études empiriques et les approches originales en termes de politique interne et/ou externe, il repose sur trois axes de recherche transversaux : la (re)définition des concepts de sécurité et d’insécurité à l’heure de la globalisation ; les enjeux inhérents aux pratiques (in)sécuritaires et aux sentiments d’(in)sécurité qui les fondent ; les réponses à apporter aux questions de sécurité et d’insécurité. Complémentaire aux analyses disciplinaires classiques de ces objets de recherche en Science politique, cet ouvrage livre un regard neuf sur des thématiques plus que jamais d’actualité. [less ▲]

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See detailLe faussaire
Havelange, Carl ULg

in Durante, Erica (Ed.) De l'humain au post-humain: le double et ses récits (in press)

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See detailProgress on research on rodents and rodent-borne zoonoses in Southeast Asia
Blasdell, Kim; Bordes, Frédéric; Chaisiri, Kittipong et al

in Wildlife Research (in press)

This review aims to synthesize the knowledge on the taxonomy of Southeast Asian murine rodents and the challenges associated with the identification of habitat preferences and associated rodent-borne ... [more ▼]

This review aims to synthesize the knowledge on the taxonomy of Southeast Asian murine rodents and the challenges associated with the identification of habitat preferences and associated rodent-borne diseases. Recent studies concerning the Rattini tribe have identified unclear species boundaries that would benefit from further investigation. The development of barcoding may allow more accurate identification of rodents, specifically for complex species. However, knowledge on the distribution and habitat specializations of many common murine rodents is still scarce, particularly regarding the specific habitat preferences of most synanthropic rodent species (Rattus tanezumi or Rattus exulans). Several studies have analyzed the prevalence of major rodent-borne diseases in Southeast Asia and it appears that the greatest risk of rodent zoonoses are in the lowland rainfed and irrigated landscapes, generally in and around rice fields. [less ▲]

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See detailAnalytical Procedure Validation and the Quality by Design Paradigm
Rozet, Eric ULg; Rozet, Eric

in Journal of Biopharmaceutical Statistics (in press)

Since the adoption of the ICH Q8 document concerning the development of pharmaceutical processes following a Quality by Design (QbD) approach, there have been many discussions on the opportunity for ... [more ▼]

Since the adoption of the ICH Q8 document concerning the development of pharmaceutical processes following a Quality by Design (QbD) approach, there have been many discussions on the opportunity for analytical procedure developments to follow a similar approach. While development and optimization of analytical procedure following QbD principles have been largely discussed and described, the place of analytical procedure validation in this framework has not been clarified. This article aims at showing that analytical procedure validation is fully integrated into the QbD paradigm and is an essential step in developing analytical procedure that are effectively fit for purpose. Adequate statistical methodologies have also their role to play: such as design of experiments, statistical modelling and probabilistic statements. The outcome of analytical procedure validation is also an analytical procedure Design Space and from it, control strategy can be set. [less ▲]

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See detailImaging myeloma and related monoclonal plasma cell disorders: Still room for standard radiography?
WITHOFS, Nadia ULg; Nanni, Cristina; Fanti, Stefano et al

in Clin.Translat.Imaging (in press)

A majority of multiple myeloma patients present with osteolytic bone lesions that can cause bone pain, fractures or hypercalcaemia. Correct identification of these lesions is important in the initial ... [more ▼]

A majority of multiple myeloma patients present with osteolytic bone lesions that can cause bone pain, fractures or hypercalcaemia. Correct identification of these lesions is important in the initial assessment of the disease. Although the radiological skeletal survey is the gold standard to detect bone osteolytic lesions, it may miss small bone lesions or lesions located in the spine or pelvis due to the superimposed images of soft tissues. These limitations propelled newer imaging techniques such as positron emission tomography combined with computed tomography (PET/CT) and magnetic resonance imaging (MRI) in the diagnosis of multiple myeloma. In addition, 18F-fluorodeoxyglucose PET/CT and MRI have prognostic value and can be used to monitor disease. This review discusses the additional value of PET/CT and MRI in the management of MM. [less ▲]

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See detailSafety and efficacy of azacitidine in Belgian patients with high-risk myelodysplastic syndromes, acute myeloid leukaemia, or chronic myelomonocytic leukaemia: results of a real-life, non-interventional post-marketing survey
Beguin, Yves ULg; Selleslag, Dominik; Meers, Stef et al

in Acta Clinica Belgica (in press)

Objectives: We evaluated azacitidine (VidazaH) safety and efficacy in patients with myelodysplastic syndrome (MDS), acute myeloid leukaemia (AML), and chronic myelomonocytic leukaemia (CMML), in a real ... [more ▼]

Objectives: We evaluated azacitidine (VidazaH) safety and efficacy in patients with myelodysplastic syndrome (MDS), acute myeloid leukaemia (AML), and chronic myelomonocytic leukaemia (CMML), in a real-life setting. Treatment response, dose, and schedule were assessed. Methods: This non-interventional, post-marketing survey included 49/50 patients receiving azacitidine at 14 Belgian haematology centres from 2010–2012. Treatment-emergent adverse events (TEAEs), including treatment-related TEAEs, and serious TEAEs (TESAEs) were recorded throughout the study. Treatment response [complete response (CR), partial response (PR), haematological improvement (HI), stable disease (SD), treatment failure (TF)) and transfusion-independence (TI) were evaluated at completion of a 1-year observation period (1YOP) or at treatment discontinuation, and overall survival (OS), at study conclusion. Results: The median age of patients was 74.7 (range: 43.9–87.8) years; 69.4% had MDS, 26.5% had primary or secondary AML, and 4.1% had CMML. Treatment-related TEAEs, grade 3–4 TEAEs, and TESAEs were reported in 67.3%, 28.6%, and 18.4% of patients, respectively. During 1YOP, patients received a median of 7 (1–12) treatment cycles. Treatment response was assessed for 38/49 patients. Among MDS and CMML patients (n529), 41.4% had CR, PR, or HI, 41.4% had SD, and 17.2% had TF. Among AML patients (n59), 44.4% had CR or PR, 33.3% had SD, and 22.2% had TF. TI was observed in 14/32 (43.8%) patients who were transfusion-dependent at baseline. Median (95% confidence interval) OS was 490 (326–555) days; 1-year OS estimate was 0.571 (0.422–0.696). Conclusions: Our data support previous findings that azacitidine has a clinically acceptable safety profile and shows efficacy. [less ▲]

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See detailThe use of mesenchymal stromal cells in solid organ transplantation
GREGOIRE, Céline ULg; DETRY, Olivier ULg; Jouret, François ULg et al

in The Biology and Therapeutic Applications of Mesenchymal Cells (in press)

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See detailThe role of mesenchymal stem cells in the treatment of ulcerative colitis and Crohn's disease
GREGOIRE, Céline ULg; Louis, Edouard ULg; BRIQUET, Alexandra ULg et al

in The Biology and Therapeutic Applications of Mesenchymal Cells (in press)

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See detailSignes dans les textes, texte sur les signes. Actes du Colloque international. Liège, 6-7 septembre 2013.
Macedo, Gabriel ULg; Scappaticcio, Maria Chiara

Book published by Presses Universitaires de Liège (in press)

Proceedings of the international conference held at the University of Liège in 2013. Contributions on the subject of ponctuation, accentuation, critical and lectional signs in Greek and Latin texts.

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See detailJuvenal in Antinoë. Paleographic and Contextual Observations on P.Ant. s.n.
Macedo, Gabriel ULg

in Urbanik, Jakub (Ed.) Proceedings of the 27th International Congress of Papyrology. Warsaw, 29 July - 3 August 2013 (in press)

Paleographic and contextual study of the only Juvenal manuscript found in Egypt.

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See detailTextes sur les signes: les sources latines
Macedo, Gabriel ULg

in Macedo, Gabriel; Scappaticcio, Maria Chiara (Eds.) Signes dans les textes, textes sur les signes. Actes du colloque international. Liège, 6-7 septembre 2013. (in press)

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See detailIl fragmentum Antinoense e la fortuna di Giovenale nell'Oriente greco
Macedo, Gabriel ULg

in Stramaglia, Antonio; Grazzini, Stefano; Dimatteo, Giuseppe (Eds.) Giovenale tra poesia, storia e ideologia. (in press)

A study of the reception of Juvenal's Satires in the Greek-speaking world, with special attention to the manuscript fragment found in Antinoe.

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See detailConfusion des codes graphiques dans les papyrus latins
Rochette, Bruno ULg; Macedo, Gabriel ULg

in Capasso, Mario; De Nonno, Mario (Eds.) Miscellanea di studi in onore di Paolo Radiciotti (in press)

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See detailPremier Aperçu de la céramique de Bash Tapa
Mas, Juliette ULg

in Marti, L; Nicolle, C; Shawaly, K (Eds.) Recherches en Haute Mésopotamie 2. Mission archéologique de Bash Tapa (campagnes 2012-2013) et les enjeux de la recherche dans la région d'Erbil (in press)

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See detailBash Tapa 2013 : Le sondage stratigraphique 1
Mas, Juliette ULg; Angevin, Raphaël

in Marti, L; Nicolle, C; Shawaly, K (Eds.) Recherches en Haute Mésopotamie 2. Mission archéologique de Bash Tapa (campagnes 2012-2013) et les enjeux de la recherche dans la région d'Erbil (in press)

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See detailFrancesco Salviati tra modelli letterari e figurativi
Geremicca, Antonio ULg

Book published by Campisano - 1re éd. (in press)

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See detailInfluence of process operating conditions on solvent thermal and oxidative degradation in post-combustion CO2 capture
Léonard, Grégoire ULg; Crosset, Cyril; Toye, Dominique ULg et al

in Computers & Chemical Engineering (in press)

///Document soumis, la révision doit encore être faite./// The CO2 post-combustion capture with amine solvents is modeled as a complex system interconnecting process energy consumption and solvent ... [more ▼]

///Document soumis, la révision doit encore être faite./// The CO2 post-combustion capture with amine solvents is modeled as a complex system interconnecting process energy consumption and solvent degradation and emission. Based on own experimental data, the kinetics of monoethanolamine degradation is included into a model of the CO2 capture process. The influences of operating conditions and flowsheet improvements on solvent loss and process energy requirement are quantified and validated with pilot plant data. Oxidative degradation in the absorber is identified as the major cause of solvent loss. On the contrary, thermal degradation does not appear as a major concern. Finally, this study leads to a decrease by 10% of the process exergy requirement along with a reduction by 11% of the solvent loss, all that by using a single model. Thus, this model provides a practical tool to minimize both the energy requirement and the solvent degradation by the design of large-scale CO2 capture units. [less ▲]

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See detailCommercial farming of Leiolepis guttata (Cuvier, 1829) in Binh Thuan province, Vietnam: implications for conservation and management
Rochette, Anne-Julie; Tran, Tinh ULg; De Martynoff, Abigail et al

in Herpetological Conservation and Biology (in press), 10(1),

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See detailThe aerodynamic cost of head morphology in bats: maybe not as bad as it seems
Vanderelst, Dieter; Peremans, Herbert; Abdul Razak, Norizham et al

in PLoS ONE (in press)

At first sight, echolocating bats face a difficult trade-off. As flying animals, they would benefit from a streamlined geometric shape to reduce aerodynamic drag and increase flight efficiency. However ... [more ▼]

At first sight, echolocating bats face a difficult trade-off. As flying animals, they would benefit from a streamlined geometric shape to reduce aerodynamic drag and increase flight efficiency. However, as echolocating animals, their pinnae generate the acoustic cues necessary for navigation and foraging. Moreover, species emitting sound through their nostrils often feature elaborate noseleaves that help in focussing the emitted echolocation pulses. Both pinnae and noseleaves reduce the streamlined character of a bat’s morphology. It is generally assumed that by compromising the streamlined charactered of the geometry, the head morphology generates substantial drag, thereby reducing flight efficiency. In contrast, it has also been suggested that the pinnae of bats generate lift forces counteracting the detrimental effect of the increased drag. However, very little data exist on the aerodynamic properties of bat pinnae and noseleaves. In this work, the aerodynamic forces generated by the heads of seven species of bats, including noseleaved bats, are measured by testing detailed 3D models in a wind tunnel. Models of Myotis daubentonii, Macrophyllum macrophyllum, Micronycteris microtis, Eptesicus fuscus, Rhinolophus formosae, Rhinolophus rouxi and Phyllostomus discolor are tested. The results confirm that non-streamlined facial morphologies yield considerable drag forces but also generate substantial lift. The net effect is a slight increase in the lift-to-drag ratio. Therefore, there is no evidence of high aerodynamic costs associated with the morphology of bat heads [less ▲]

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