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See detailLes MARC's
Balon, Françoise; Nyssen, Anne-Sophie ULg

in Larcier (Ed.) Les modes Alternatifs de Règlement des conflits (2014)

Les Modes Alternatifs de Règlement des Conflits

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See detailA one phase thermomechanical model for the numerical simulation of semi-solid material behavior. Application to thixoforming
Koeune, Roxane; Ponthot, Jean-Philippe ULg

in International Journal of Plasticity (2014), 58

This work deals with the development of an appropriate constitutive model for semi-solid thixoforming processes of metallic alloys. These processes rely on a very specific material behavior called ... [more ▼]

This work deals with the development of an appropriate constitutive model for semi-solid thixoforming processes of metallic alloys. These processes rely on a very specific material behavior called thixotropy that can be displayed by some metallic alloys heated up to their semi-solid state. It is a particular evolutionary behavior which is characterized by a solidlike behavior at rest and a liquid flow during shearing, thus by a decrease of the viscosity and of the resistance to deformation while sheared. An original one-phase thermo-elasto-viscoplastic constitutive model has been developed. The basic idea is to extend the classical isotropic hardening and viscosity models beyond the solid state by considering two more non-dimensional internal scalar parameters. The semi-solid state is treated as a particular case, and one of the main features of the proposed constitutive model is that it remains valid over a wide range of temperatures, starting from room temperature to above the liquidus in a continuous manner, thus allowing a continuous transition between classical solid and fluid behavior. Another feature is that, after the forming step, it is possible to simulate the cooling down of the component back to room temperature using the elastic–viscoplastic model. So it is possible to estimate residual stresses, something that is definitely impossible while using a fluid-like model or a rigid viscoplastic approach. The presented model is illustrated and validated by means of representative numerical applications, as two different extrusion tests are carried out and the computed predictions are compared to experimental results. [less ▲]

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See detailEosinophilic Bronchopneumopathy
Clercx, Cécile ULg

in Proceedings 35 Internationaler Fortbildungskurs Kleintierkrankheiten (2014)

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See detailEffects of adenosine on lymphangiogenesis.
Lenoir, Bénédicte ULg; Wagner, Daniel R.; Blacher, Silvia ULg et al

in PloS one (2014), 9(3), 92715

BACKGROUND: The lymphatic system controls tissue homeostasis by draining protein-rich lymph to the vascular system. Lymphangiogenesis, the formation of lymphatic vessels, is a normal event in childhood ... [more ▼]

BACKGROUND: The lymphatic system controls tissue homeostasis by draining protein-rich lymph to the vascular system. Lymphangiogenesis, the formation of lymphatic vessels, is a normal event in childhood but promotes tumor spread and metastasis during adulthood. Blocking lymphangiogenesis may therefore be of therapeutic interest. Production of adenosine is enhanced in the tumor environment and contributes to tumor progression through stimulation of angiogenesis. In this study, we determined whether adenosine affects lymphangiogenesis. METHODS: Lymphatic endothelial cells (HMVEC-dLy) were cultured in presence of adenosine and their proliferation, migration and tube formation was assessed. Gelatin sponges embedded with the stable analogue of adenosine 2-chloro adenosine were implanted in mice ear and lymphangiogenesis was quantified. Mice were intravenously injected with adenoviruses containing expression vector for 5'-endonucleotidase, which plays a major role in the formation of adenosine. RESULTS: In vitro, we observed that adenosine decreased the proliferation of lymphatic endothelial cells, their migration and tube formation. However, in vivo, gelatin sponges containing 2-chloro adenosine and implanted in mice ear displayed an elevated level of lymphangiogenesis (2.5-fold, p<0.001). Adenovirus-mediated over-expression of cytosolic 5'-nucleotidase IA stimulated lymphangiogenesis and the recruitment of macrophages in mouse liver. Proliferation of lymphatic endothelial cells was enhanced (2-fold, p<0.001) when incubated in the presence of conditioned medium from murine macrophages. CONCLUSION: We have shown that adenosine stimulates lymphangiogenesis in vivo, presumably through a macrophage-mediated mechanism. This observation suggests that blockade of adenosine receptors may help in anti-cancer therapies. [less ▲]

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See detailInitial uncertainty in Pavlovian reward prediction persistently elevates incentive salience and extends sign-tracking to normally unattractive cues
Robinson, Mike J.F.; Anselme, Patrick ULg; Fischer, Adam M. et al

in Behavioural Brain Research (2014), 266(1), 119-130

Uncertainty is a component of many gambling games and may play a role in incentive motivation and cue attraction. Uncertainty can increase the attractiveness for predictors of reward in the Pavlovian ... [more ▼]

Uncertainty is a component of many gambling games and may play a role in incentive motivation and cue attraction. Uncertainty can increase the attractiveness for predictors of reward in the Pavlovian procedure of autoshaping, visible as enhanced sign-tracking (or approach and nibbles) by rats of a metal lever whose sudden appearance acts as a conditioned stimulus (CS+) to predict sucrose pellets as an unconditioned stimulus (UCS). Here we examined how reward uncertainty might enhance incentive salience as sign-tracking both in intensity and by broadening the range of attractive CS+s. We also examined whether initially-induced uncertainty enhancements of CS+ attraction can endure beyond uncertainty itself, and persist even when Pavlovian prediction becomes 100% certain. Our results show that uncertainty can broaden incentive salience attribution to make CS cues attractive that would otherwise not be (either because they are too distal from reward or too risky to normally attract sign-tracking). In addition, uncertainty enhancement of CS+ incentive salience, once induced by initial exposure, persisted even when Pavlovian CS-UCS correlations later rose toward 100% certainty in prediction. Persistence suggests an enduring incentive motivation enhancement potentially relevant to gambling, which in some ways resembles incentive-sensitization. Higher motivation to uncertain CS+s leads to more potent attraction to these cues when they predict the delivery of uncertain rewards. In humans, those cues might possibly include the sights and sounds associated with gambling, which contribute a major component of the play immersion experienced by problematic gamblers. [less ▲]

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See detailV. Van Saaze, Installation Art and the Museum : Presentation and Conservation of Changing Artworks
D'Haenens, Manon ULg

in CeROArt : Conservation, Exposition, Restauration d'Objets d'Art (2014), (9),

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See detailNanocomposite fiber reinforced mortars
Coppola, Bartolomeo; Di Maio, Luciano; Courard, Luc ULg et al

in Proceedings of the International Conference on Composites/Nano Engineering (2014)

The use of fibers to reinforce a brittle material is an extensively studied application. In the field of cementitious materials a wide range of fibers have been investigated, from natural to synthetic ... [more ▼]

The use of fibers to reinforce a brittle material is an extensively studied application. In the field of cementitious materials a wide range of fibers have been investigated, from natural to synthetic fiber (wood, cellulose, carbon, glass, polypropylene) in order to achieve several purposes. Nowadays there is a continuing effort to take advantage of recent advances in nanotechnology, in the polymer and fiber industry. Nanoclays are some of the most affordable materials that have shown promising results in nanocomposite polymers. They are characterized by a “platelet” structure with average dimension of 1 nm thick and 70 to 150 nm wide. This work is aimed at studying the different behavior of fiber reinforced mortars, containing nanocomposite polymeric fibers. [less ▲]

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See detailLes racines de l’Occident (jusqu’au Xe siècle)
Jadoulle, Jean-Louis ULg; GEORGES, Jean

Book published by Didier Hatier - 2ème éd. (2014)

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See detailLes racines de l'Occident (jusqu'au Xe s.)
Jadoulle, Jean-Louis ULg; Georges, Jean

Book published by Didier Hatier - 2ème éd. (2014)

Cet ouvrage constitue la nouvelle édition du manuel scolaire édité, sous le même titre, en 2005. Il est toutefois assorti, à présent, d'un manuel numérique enrichi entièrement nouveau.

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See detailFers et bois dans les combles médiévaux et modernes du sud de la Belgique. Contribution à l'histoire de la construction en Europe occidentale
Maggi, Christophe ULg

Doctoral thesis (2014)

After four years of doctoral research on the topic of iron in the roof framing, a detailed typologic timeline could be established. It covers the period between the thirteenth and eighteenth century. The ... [more ▼]

After four years of doctoral research on the topic of iron in the roof framing, a detailed typologic timeline could be established. It covers the period between the thirteenth and eighteenth century. The development of such an inventory was possible by the development of an interdisciplinary methodology combining dendrochronology, archaeometallurgy and techniques of building archeology. Reflections and comparisons crossed with nearly 750 armatures from the investigation of 68 roof or attic parts, mainly located in Wallonia, helped to inventory 89 differents frames iron models. [less ▲]

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See detailTraditional plant-based remedies to control gastrointestinal disorders in livestock in the regions of Kamina and Kaniama (Katanga province, Democratic Republic of Congo)
Okombe Embeya, Victor; Lumbu Simbi, Jean-Baptiste; Stévigny, Caroline et al

in Journal of Ethnopharmacology (2014), 153(3), 686-693

Ethnopharmacological relevance: gastrointestinal parasitic diseases present one of the main constraints hindering the productivity of the livestock sector (goat and cattle). Due to the limited ... [more ▼]

Ethnopharmacological relevance: gastrointestinal parasitic diseases present one of the main constraints hindering the productivity of the livestock sector (goat and cattle). Due to the limited availability and affordability of deworming drugs, traditional herbal remedies are still frequently used. The study aims at collecting traditional knowledge on local plants and remedies used to treat gastrointestinal parasitoses in livestock in two adjacent territories (Haut-Lomami district). Material and methods: A field survey was carried out in a part of the Haut-Lomami district (province of Katanga). A semi-structured questionnaire was used to interview 44 people including farmers, traditional healers and livestock specialists (veterinarians and agronomist), identified as using or practicing traditional medicine. To prepare botanically identified herbarium specimens, cited plants were collected with the participation of interviewed people. Results: Although interviewed people cannot precisely identify the etiology of gastrointestinal disorders/parasitoses in domestic animals, they treat the condition with herbals collected in their near environment. Nineteen different traditional remedies were collected and described; 9 plant species were identified as commonly used to treat gastrointestinal parasitic infections. From these, Vitex thomasii De Wild (Verbenaceae) appears as the plant most often used. Conclusion: this survey contributed to the establishment of an inventory of plants used in livestock parasitic treatment in this region of the Democratic Republic of Congo. Future studies are needed to confirm the efficacy and safety of these traditional remedies. [less ▲]

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See detailEffect of the ratio of dietary n-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid on broiler breeder performance, egg quality, and yolk fatty acid composition at different breeder ages.
Koppenol, A.; Delezie, E.; Aerts, J. et al

in Poultry science (2014), 93(3), 564-73

When added to the feed of broiler breeder hens, dietary polyunsaturated fatty acids (FA) can be incorporated into the yolk and therefore become available to the progeny during their early development. The ... [more ▼]

When added to the feed of broiler breeder hens, dietary polyunsaturated fatty acids (FA) can be incorporated into the yolk and therefore become available to the progeny during their early development. The mechanism involved in lipid metabolism and deposition in the egg may be influenced by breeder age. Before the effect of an elevated concentration of certain polyunsaturated FA on the embryo can be investigated, the effect at breeder level and egg quality must be further assessed. The aim of the present experiment was to evaluate the effects of dietary n-6/n-3 ratios and dietary eicosapentaenoic acid (EPA, 20:5 n-3) and docosahexaenoic acid (DHA, 22:6 n-3) ratios, provided to broiler breeder hens, in terms of their zoo technical performance, egg quality, and yolk FA composition. Starting at 6 wk of age, 640 Ross-308 broiler breeder hens were fed 1 of 4 different diets. The control diet was a basal diet, rich in n-6 FA. The 3 other diets were enriched in n-3 FA, formulated to obtain a different EPA/DHA ratio of 1/1 (EPA = DHA), 1/2 (DHA), or 2/1 (EPA). In fact, after analysis the EPA/DHA ratio was 0.8, 0.4, or 2.1, respectively. Dietary EPA and DHA addition did not affect the performance of the breeder hens, except for egg weight. Egg weight was lower (P < 0.001) for all n-3 treatments. Dietary EPA improved number of eggs laid in the first 2 wk of the production cycle (P = 0.029). The absolute and relative yolk weight of eggs laid by EPA = DHA fed hens was lowest (P = 0.004 and P = 0.025, respectively). The EPA and DHA concentrations in the yolk were highly dependent on dietary EPA and DHA concentrations with a regression coefficient equal to 0.89. It can be concluded that dietary EPA and DHA can be incorporated in the breeder egg yolk to become available for the developing embryo, without compromising the performance and egg quality of the flock. [less ▲]

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See detailDe la nullité des décisions de l’assemblée générale des sociétés coopératives
Léonard, Laura ULg; Caprasse, Olivier ULg

in Le droit des affaires = Het ondernemingsrecht (2014), 109

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See detailValidity and Reliability of the French version of the STarT Back Screening Tool for patients with low back pain.
Bruyère, Olivier ULg; Demoulin, Maryline; Beaudart, Charlotte ULg et al

in Spine (2014), 39(2), 123-128

Study Design. Observational prospective study.Objective. Our objective was to assess the reliability and validity of the French version of the Keele STarT Back Screening Tool (SBST).Summary of Background ... [more ▼]

Study Design. Observational prospective study.Objective. Our objective was to assess the reliability and validity of the French version of the Keele STarT Back Screening Tool (SBST).Summary of Background Data. The SBST is a recently validated tool developed to identify subgroups of patients with low back pain (LBP) to guide early secondary prevention in primary care.Methods. Outpatients with LBP aged 18 years or more, attending a rehabilitation centre, a back school, a private physiotherapy unit or a fitness centre were included. Patients were assessed through the SBST, Roland-Morris Disability Questionnaire (RMDQ), Orebro Musculoskeletal Pain Screening Questionnaire (OMPSQ), Medical Outcomes Survey Short Form 36 (SF-36) questionnaire, and a pain visual analogic scale (VAS). Test-retest reliability was assessed with Kappa score or the intraclass correlation coefficient (ICC), internal consistency of the psychological subscale with the Cronbach alpha coefficient, construct validity with the Spearman's correlation coefficient, and floor and ceiling effects by percentage frequency of lowest or highest possible score achieved by respondents.Results. 108 patients with LBP were included. The test-retest reliability of the SBST total score was excellent with an ICC of 0.90 (0.81-0.95). The Cronbach alpha coefficient was 0.73 showing a good internal consistency for the psychological subscale. High Spearman's correlation coefficients of 0.74 between SBST and RMDQ, and 0.74 between the SBST and OMPSQ were observed. As expected, low to moderate correlations were observed between the SBST total score and some dissimilar measures of the SF-36. The lowest possible SBST score was observed for 8 patients (7.4%) whereas only three patients (2.8%) had the highest possible SBST score.Conclusion. The French version of the SBST is a reliable and valid questionnaire consistent with the original English version. Therefore, this new version may help French-speaking clinicians and scientists to stratify patients with LBP. [less ▲]

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See detailRobot-assisted laparoscopy for deep infiltrating endometriosis: international multicentric retrospective study.
Collinet, Pierre; Leguevaque, Pierre; Neme, Rosa Maria et al

in Surgical Endoscopy (2014), sous presse

BACKGROUND: This study aimed to assess the interest in robot-assisted laparoscopy for deep infiltrating endometriosis and to investigate the perioperative results. METHODS: From November 2008 to April ... [more ▼]

BACKGROUND: This study aimed to assess the interest in robot-assisted laparoscopy for deep infiltrating endometriosis and to investigate the perioperative results. METHODS: From November 2008 to April 2012, 164 women with stage 4 endometriosis who underwent robot-assisted laparoscopy (da Vinci Intuitive Surgical System) were included by to eight international participating clinical centers. This study evaluated the procedures performed, the duration of the intervention, the complications, the recurrence, and the impact on fertility. RESULTS: The average operative time was 180 min. The main complications were laparotomy (n = 1, 0.6 %), sutured bowel injury (n = 2, 1.2 %), transfusion for a 2,300-ml bleed (n = 1), prolonged urinary catheterization (n = 1, 0.6 %), ureter-bladder anastomotic leak (n = 1, 0.6 %), and ureteral fistula after ureterolysis (n = 2, 1.2 %). The reoperation rate was 1.8 % (n = 3). The mean follow-up period was 10.2 months. A full recovery was experienced by 86.7 % (98/113) of the patients. After surgery, 41.2 % (42/102) of the patients had a desire for pregnancy, and 28.2 % (11/39) of them became pregnant. CONCLUSION: This study analyzed the largest series of robot-assisted laparoscopies for deep infiltrating endometriosis published in the literature. No increase in surgical time, blood loss, or intra- or postoperative complications was observed. The interest in robot-assisted laparoscopy for deep infiltrating endometriosis seems to be promising. [less ▲]

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See detailFlore et faune de l'estran. Régions de Wimereux (Pas-de-Calais) et de Roscoff (Finistère)
Bussers, Jean-Claude ULg; Jeuniaux, Charles; Thomé, Jean-Pierre ULg et al

Learning material (2014)

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See detaildivand-1.0: n-dimensional variational data analysis for ocean observations
Barth, Alexander ULg; Beckers, Jean-Marie ULg; Troupin, Charles ULg et al

in Geoscientific Model Development (2014), 7

A tool for multidimensional variational analysis (divand) is presented. It allows the interpolation and analysis of observations on curvilinear orthogonal grids in an arbitrary high dimensional space by ... [more ▼]

A tool for multidimensional variational analysis (divand) is presented. It allows the interpolation and analysis of observations on curvilinear orthogonal grids in an arbitrary high dimensional space by minimizing a cost function. This cost function penalizes the deviation from the observations, the deviation from a first guess and abruptly varying fields based on a given correlation length (potentially varying in space and time). Additional constraints can be added to this cost function such as an advection constraint which forces the analysed field to align with the ocean current. The method decouples naturally disconnected areas based on topography and topology. This is useful in oceanography where disconnected water masses often have different physical properties. Individual elements of the a priori and a posteriori error covariance matrix can also be computed, in particular expected error variances of the analysis. A multidimensional approach (as opposed to stacking 2-dimensional analysis) has the benefit of providing a smooth analysis in all dimensions, although the computational cost is increased. Primal (problem solved in the grid space) and dual formulations (problem solved in the observational space) are implemented using either direct solvers (based on Cholesky factorization) or iterative solvers (conjugate gradient method). In most applications the primal formulation with the direct solver is the fastest, especially if an a posteriori error estimate is needed. However, for correlated observation errors the dual formulation with an iterative solver is more efficient. The method is tested by using pseudo observations from a global model. The distribution of the observations is based on the position of the ARGO floats. The benefit of the 3-dimensional analysis (longitude, latitude and time) compared to 2-dimensional analysis (longitude and latitude) and the role of the advection constraint are highlighted. The tool divand is free software, and is distributed under the terms of the GPL license (http://modb.oce.ulg.ac.be/mediawiki/index.php/divand). [less ▲]

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See detailA longitudinal study of ABC transporter expression in canine multicentric lymphoma.
Zandvliet, M.; Teske, Erik ULg; Schrickx, J. A. et al

in Veterinary journal (London, England : 1997) (2014)

Canine lymphoma is typically treated with a doxorubicin-based multidrug chemotherapy protocol. Although this is often initially successful, tumour recurrence is common and frequently refractory to ... [more ▼]

Canine lymphoma is typically treated with a doxorubicin-based multidrug chemotherapy protocol. Although this is often initially successful, tumour recurrence is common and frequently refractory to treatment. Failure to respond to chemotherapy is thought to represent drug resistance and has been associated with active efflux of cytostatic drugs by transporter proteins of the ATP-binding cassette (ABC) family, including P-glycoprotein (ABCB1), MRP1 (ABCC1) and BCRP (ABCG2). In this study, ABC transporter mRNA expression was assessed in 63 dogs diagnosed with multicentric lymphoma that were treated with a doxorubicin-based chemotherapy protocol. Expression of ABCB1, ABCB5, ABCB8, ABCC1, ABCC3, ABCC5 and ABCG2 mRNA was quantified in tumour samples (n = 107) obtained at the time of diagnosis, at first tumour relapse and when the tumour was no longer responsive to cytostatic drugs while receiving chemotherapy. Expression data were related to patient demographics, staging, treatment response and drug resistance (absent, intrinsic, acquired). ABC transporter expression was independent of sex, weight, age, stage or substage, but T cell lymphoma and hypercalcaemia were associated with increased ABCB5 and ABCC5 expression, and decreased ABCC1 mRNA expression. Drug resistance occurred in 35/63 (55.6%) dogs and was associated with increased ABCB1 mRNA expression in a subset of dogs with B cell lymphoma, and with increased ABCG2 and decreased ABCB8, ABCC1 and ABCC3 mRNA expression in T cell lymphomas. ABC transporter expression in the pre-treatment sample was not predictive of the length of the first disease-free period or overall survival. Glucocorticoids had no effect on ABC transporter mRNA expression. In conclusion, drug resistance in canine multicentric lymphoma is an important cause of treatment failure and is associated with upregulation of ABCB1 and ABCG2 mRNA. [less ▲]

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