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See detailUNE INJECTION UNIQUE DE CELLULES STROMALES MESENCHYMATEUSES AU JOUR 3 APRES GREFFE HEPATIQUE EST INSUFFISANTE POUR INDUIRE UNE TOLERANCE OPERATIONNELLE
DETRY, Olivier ULg; VANDERMEULEN, Morgan ULg; DELBOUILLE, Marie-Hélène ULg et al

in Transplant International (2017, January), 30(suppl 1), 812

Introduction: Mesenchymal stromal cell (MSC) infusion could be a mean to establish donor-specific immunological tolerance in solid organ recipients. The aim of this phase 2 study was test the hypothesis ... [more ▼]

Introduction: Mesenchymal stromal cell (MSC) infusion could be a mean to establish donor-specific immunological tolerance in solid organ recipients. The aim of this phase 2 study was test the hypothesis of possible induction of operative tolerance by third-party MSC in liver transplant (LT) recipients. Methods: 10 stable and low-risk LT recipients under standard immunosup- pression (Tac-MMF- low dose steroids) received 1.5–3 9 106/kg third-party MSCs on post-operative day 3 ` 2. By protocol, progressive weaning of immunosuppression was attempted in patients who did not develop rejection and had normal graft function and month-6 graft biopsy. Tacrolimus was progressively tapered from day 180 to be discontinued by day 270. After day- 270 graft biopsy, MMF was progressively tapered and definitely discontinued by day 365 in the absence of rejection. Results: One patient from the MSC group was excluded from immunosup- pression withdrawal attempt due to HCC recurrence, and the 9 others met the necessary criteria. In one patient, tacrolimus and MMF withdrawal was performed without rejection. In two patients, MMF monotherapy was achieved at month 9, but graft rejection occurred during MMF withdrawal and was successfully treated by tacrolimus reintroduction. In 6 patients, the transam- inases significantly increased during tacrolimus withdrawal. In these cases, withdrawal was cancelled and liver tests normalised after increase of the tacrolimus dose. No graft was lost due to the withdrawal attempt. Conclusion: A single post transplant MSC injection is not sufficient to induce operative tolerance after LT. [less ▲]

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See detailLa «Health Literacy»,un moyen pour réduire les inégalités sociales de santé
Bragard, Isabelle ULg; COUCKE, Philippe ULg; Pétré, Benoît ULg et al

in Revue Médicale de Liège (2017), 72(1),

Health literacy (HL) is defined as ‘the knowledge, motivation, and competences to access, understand, appraise and apply health information in order to make judgments and take decisions in everyday life ... [more ▼]

Health literacy (HL) is defined as ‘the knowledge, motivation, and competences to access, understand, appraise and apply health information in order to make judgments and take decisions in everyday life concerning health care, disease prevention and health promotion to maintain or improve quality of life’. This concept begins to be recognized as a priority area for action at political level in Belgium. Indeed, a limited HL may affect health by leading, by example, with poorer management of chronic diseases, more hospital admissions and premature deaths. This paper addresses the question of HL evaluation, improvement interventions as well as the many challenges that remain in this area. HL seems fundamental to the development of better health management. It would allow patients to play a more active role in health care, to involve all health stakeholders, and to contribute to a more sustainable health system. Improving HL could allow better equal access to health care. [less ▲]

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See detailRapport final de la convention de recherche: "DEPITRIM: Detection, control measures and impact study of Epitrix in Belgium"
Maes, Martine; Jansen, Jean-Pierre; De Clercq, Patrick et al

Report (2017)

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See detailDu bon usage des faits en régime de " post­-vérité"
Thoreau, François ULg; Zimmer, Alexis

Article for general public (2017)

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See detailExploring Metacognition as Support for Learning Transfer
Scharff, Lauren; Draeger, John; Verpoorten, Dominique ULg et al

in Teaching & Learning Inquiry: The ISSoTL Journal (2017), 5(1),

The ability to transfer learning to new situations lies at the heart of lifelong learning and the employability of university graduates. Because students are often unaware of the importance of learning ... [more ▼]

The ability to transfer learning to new situations lies at the heart of lifelong learning and the employability of university graduates. Because students are often unaware of the importance of learning transfer and staff do not always explicitly articulate this expectation, this article explores the idea that metacognition (intentional awareness and the use of that awareness) might enhance the development of learning transfer. Our exploratory study includes results from a survey of 74 staff and 118 students from five institutions in Australia, Belgium, UK, and USA. Our data indicate that many staff and a majority of students do not have a clear understanding of what learning transfer entails, and that there are many mismatches between staff and student perceptions, attitudes, and behaviors regarding learning transfer. This helps explain why learning transfer does not occur as often as it could. We found significant positive correlations between thinking about transfer and thinking about learning processes and the likelihood to use awareness of metacognition to guide practice. Our findings suggest a positive relationship between metacognition and learning transfer. Implications for scholarship of teaching and learning are discussed. [less ▲]

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See detailPost-embryonic development of sheepshead minnow Cyprinodon variegatus: a staging tool based on externally visible anatomical traits
Schnitzler, Joseph ULg; Dussenne, Mélanie ULg; Frederich, Bruno ULg et al

in Ichthyological Research (2017), 64

The sheepshead minnow Cyprinodon variegatus has become a favoured model for laboratory studies because of their small size, rapid development, and tolerance of laboratory conditions. Here, we analyse ... [more ▼]

The sheepshead minnow Cyprinodon variegatus has become a favoured model for laboratory studies because of their small size, rapid development, and tolerance of laboratory conditions. Here, we analyse sheepshead minnow post-embryonic development with the goal of providing a generally useful method for staging fish after embryogenesis. Groups of three females and two males were placed in breeding chambers designed for this experiment. More than 100 eggs were collected and maintained in seawater. Embryos were selected under a dissection microscope and placed in incubation dishes (50 per dish) at 26 °C. On day six, embryos hatched and larvae were transferred to 1 L beakers. To define a simplified normalization table for sheepshead minnow development, we measured each fish for its standard length and examined the fish for four externally evident traits: pigmentation pattern, caudal fin morphology, anal fin morphology, and dorsal fin morphology. The four traits were chosen, because they are easily visualized with standard laboratory equipment such as the stereomicroscope and camera. We have provided criteria for staging sheepshead minnows in studies of post-embryonic development. Our data suggest that dorsal and anal fin morphology may serve as a useful phenotype for defining metamorphic climax stages throughout post-embryonic development in C. variegatus. The staging systems we propose should facilitate detailed anatomical and developmental analyses in relation to ecotoxicological studies on potential disruption of the thyroid axis by xenobiotics and endocrine-disrupting compounds. [less ▲]

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See detailHabitat selection by marine larvae in changing chemical environments
Lecchini, David; Dixson, Danielle L.; Lecellier, Gael et al

in Marine Pollution Bulletin (2017), 114

The replenishment and persistence of marine species is contingent on dispersing larvae locating suitable habitat and surviving to a reproductive stage. Pelagic larvae rely on environmental cues to make ... [more ▼]

The replenishment and persistence of marine species is contingent on dispersing larvae locating suitable habitat and surviving to a reproductive stage. Pelagic larvae rely on environmental cues to make behavioural decisions with chemical information being important for habitat selection at settlement. We explored the sensory world of crustaceans and fishes focusing on the impact anthropogenic alterations (ocean acidification, red soil, pesticide) have on conspecific chemical signals used by larvae for habitat selection. Crustacean (Stenopus hispidus) and fish (Chromis viridis) larvae recognized their conspecifics via chemical signals under control conditions. In the presence of acidified water, red soil or pesticide, the ability of larvae to chemically recognize conspecific cues was altered. Our study highlights that recruitment potential on coral reefs may decrease due to anthropogenic stressors. If so, populations of fishes and crustaceans will continue their rapid decline; larval recruitment will not replace and sustain the adult populations on degraded reefs. [less ▲]

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See detailLessons learned from the virus indexing of Musa germplasm: insights from a multiyear collaboration
De Clerck, Caroline ULg; Crew, Kathy; Van den Houwe, Ines et al

in Annals of Applied Biology (2017)

The Bioversity International Transit Center (ITC) for banana hosts more than 1500 accessions largely covering the genetic diversity of the genus Musa. Its objective is to conserve this genetic diversity ... [more ▼]

The Bioversity International Transit Center (ITC) for banana hosts more than 1500 accessions largely covering the genetic diversity of the genus Musa. Its objective is to conserve this genetic diversity and to supply plant materials to users worldwide. All the Musa accessions must be tested for virus presence and, if infected, virus elimination must be attempted, to enable the supply of virus-free plant material. An international collaborative effort launched under the auspices of Bioversity International (2007–2013) finally led to the implementation of a two-step process to test the accessions. The first step, called pre-indexing, involved only molecular tests and was designed as a pre-screen of new germplasm lines or existing accessions to reduce the need for post-entry virus therapy and repeated virus indexing. The second step, called full indexing, was performed on either older existing accessions or newer accessions which tested negative during pre-indexing, and involvedmolecular tests, transmission electron microscopy (TEM) and symptom observation. In total, 270 germplasm lines (434 samples) were pre-indexed; while full indexing was carried out on 243 accessions (68 of which had been pre-indexed). A significant proportion of the samples tested during pre-indexing was infected with at least one virus (68%), showing the utility of this early pre-screening step. Banana streak OL virus and Banana mild mosaic virus were the most commonly detected viruses during both pre- and full indexing. For 22 accessions, viral particles were observed by TEM in full indexing while the molecular tests were negative, underlining the importance of combining various detection techniques. After full indexing, viruses were not detected in 166 accessions, which were then released for international distribution from the ITC. This publication exemplifies how the practical application of diagnostic protocols can raise fundamental questions related to their appropriate use in routine practice and the need for their continuous monitoring and improvement after their first publication. [less ▲]

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See detailH.M. Enzensberger contre l'amertume du vieillard. Des "groupes vidéos" à Youtube (et retour).
Hamers, Jérémy ULg

in Cahier Louis-Lumière (2017), 10

By interrelating several texts on the editing and juxtaposition of heterogeneous images by the German essayist and media theorist Hans Magnus Enzensberger, this article brings up to date an aesthetic link ... [more ▼]

By interrelating several texts on the editing and juxtaposition of heterogeneous images by the German essayist and media theorist Hans Magnus Enzensberger, this article brings up to date an aesthetic link between various past and contemporary media devices. The identification of this link makes it possible to free theoretical critique of the evolutionary paradigm of failure and progress (technological and political), opening it up to a set of reciprocal and non-linear insights. In this context, the use of Enzensberger texts also goes beyond any form of periodisation. By engaging a dialogue with his “Jeu de construction pour une théorie des medias” / Constituents of a Theory of the Media (1970), several essays gathered in Médiocrité et folie / Mediocrity and Madness (1988), as well as his recent autobiographical interview Erinnerungen an einen Tumult (2014), this text shows how criticism by the German writer, while constantly revitalised by the emergence of “new” objects (tabloid press, mobile video, television, Internet, smartphones), invites us to overcome any technological determinism to simultaneously consider the political potential of the first activist video groups and platforms dominating the Internet today. [less ▲]

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See detailCapitales européennes de la Culture : enjeux, dynamiques et héritages
Brahy, Rachel ULg; Dumont, Elisabeth

Article for general public (2017)

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See detailSoulèvements. Poétique et politique, une rencontre (presque) impossible
Hagelstein, Maud ULg

Article for general public (2017)

Qu’est-ce qui nous soulève ? L’exposition présentée au Jeu de Paume par Didi-Huberman répond à cette question en cinq temps, formant les chapitres d’une histoire de la révolte racontée par les moyens ... [more ▼]

Qu’est-ce qui nous soulève ? L’exposition présentée au Jeu de Paume par Didi-Huberman répond à cette question en cinq temps, formant les chapitres d’une histoire de la révolte racontée par les moyens d’une anthropologie politique des images. Comment se soulever, donc ? 1. Par éléments (déchaînés) – 2. Par gestes (intenses) – 3. Par mots (exclamés) – 4. Par conflits (embrasés) – 5. Par désirs (indestructibles). Finement orchestré et rassemblant des matériaux visuels aussi hétérogènes que singuliers, le dispositif met en place un vaste système d’échos où s’aventure le spectateur. Les éléments exposés ouvrent des brèches dans nos savoirs, se compliquent les uns les autres, se démentent et se répondent, parfois avec évidence, parfois plus confidentiellement. Des séries se créent au départ des objets exposés, sans doute différentes pour chacun, séries sur lesquelles viennent se greffer les trouvailles du commissaire au fur et à mesure du trajet dans l’exposition. [less ▲]

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See detail« Un enfant de 5 ans pourrait le faire ». Cy Twombly ou la liberté reconquise.
Hagelstein, Maud ULg

Article for general public (2017)

De nombreux observateurs ont décrit chez Twombly cette réconciliation picturale de l’adulte avec la vitalité ou la liberté enfantine, tout en marquant – bien entendu – la non-coïncidence de ses œuvres ... [more ▼]

De nombreux observateurs ont décrit chez Twombly cette réconciliation picturale de l’adulte avec la vitalité ou la liberté enfantine, tout en marquant – bien entendu – la non-coïncidence de ses œuvres avec les productions des enfants. Malgré sa sensibilité aux compositions gauches, sales, « tripotées », « déjetées » de l’artiste américain, Roland Barthes voyait chez Twombly une « paresse » (et donc une « élégance extrême ») sans commune mesure avec le caractère appliqué (on tire la langue) et appuyé du dessin d’enfant. D’autres ont pu invoquer l’intention artistique, non manifeste ou moins construite chez l’enfant. Dans son texte sur « Le corps parlant de Cy Twombly » (cf. catalogue de l’exposition), Richard Leeman rappelle que l’artiste avait apporté une réponse à ce problème, indiquant que « sa ligne est enfantine (childlike), mais pas puérile (childish) ». Twombly disait encore à ce propos : « C’est très difficile à imiter : pour avoir cette qualité, il faut se projeter soi-même dans la ligne de l’enfant, cela doit se ressentir ». Dessiner comme un enfant de 5 ans, ce n’est pas à la portée de tout le monde. Un enfant de cinq ans pourrait le faire, oui, sans doute, il pourrait en tout cas profiter encore de cette liberté que Twombly a tellement bien su convertir, mais un adulte non-artiste ne le pourrait pas. [less ▲]

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See detailSomatic mosaicism is implicated in the etiology of XLAG syndrome
Rostomyan, Liliya ULg; Daly, Adrian ULg; Yuan, Bo et al

in Abstract book : Symposium "Perspectives in Endocrinology" (2017, January)

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See detailLa polémique marxiste comme pouvoir de praxis : le rôle des revues dans la radicalisation d'un imaginaire politique
Franck, Thomas ULg

in Dacoromania Litteraria (2017), 3

On the basis of Antonio Gramsci’s praxis philosophy, taken up by André Tosel, and Cornelius Castoriadis’ works on radical imaginary, this article analyses the debate about Marxism, during the year 1946 ... [more ▼]

On the basis of Antonio Gramsci’s praxis philosophy, taken up by André Tosel, and Cornelius Castoriadis’ works on radical imaginary, this article analyses the debate about Marxism, during the year 1946, between two intellectual reviews: Les Temps Modernes and Critique. If the creation of those reviews is deeply related to a social context and an interdiscourse influenced by the political and ideological rise of extreme left – particularly the French Communist Party –, their project consists in a critical questioning of communist discourses, returning to Marx’s and Hegel’s texts. References to these philosophies induce different rhetorical and argumentative particularities that we intend to study in order to understand the complex relations between the rhetoric of a sociohistorical interdiscourse and his ideological substructure. [less ▲]

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See detailL'évaluation à la lumière des contextes et des disciplines
Detroz, Pascal ULg; Crahay, Marcel ULg; Fagnant, Annick ULg

Book published by deboeck (2017)

Cet ouvrage collectif regroupant les contributions de 11 équipes de chercheurs issus des 4 pays francophones questionne l’impact des contextes et des disciplines sur l’évaluation mais aussi, en effet ... [more ▼]

Cet ouvrage collectif regroupant les contributions de 11 équipes de chercheurs issus des 4 pays francophones questionne l’impact des contextes et des disciplines sur l’évaluation mais aussi, en effet retour, l’impact de l’évaluation, aujourd'hui omniprésente dans nos vies quotidiennes, sur les contextes et les disciplines. [less ▲]

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See detailIntroduction
Detroz, Pascal ULg; Crahay, Marcel ULg; Fagnant, Annick ULg

in Detroz, Pascal; Crahay, Marcel; Fagnant, Annick (Eds.) L'évaluation à la lumière des contextes et des disciplines (2017)

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See detailIntroduction à l’axe 3
Detroz, Pascal ULg; Younes, Nathalie

in Detroz, Pascal; Crahay, Marcel; Fagnant, Annick (Eds.) L'évaluation à la lumière des contextes et des disciplines (2017)

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