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See detailPISA expliqué à tous : pistes pour améliorer l'enseignement en FW-B
Lafontaine, Dominique ULiege

Scientific conference (2017, April 27)

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See detailImportin-8 could cause CAE/JME by delaying early neuroblast migration
Nganou, Gerry ULiege; Tanaka, Miyabi; Coumans, Bernard ULiege et al

Poster (2017, April 27)

Abstract : Childhood Absence Evolving to Juvenile Myoclonic Epilepsy (CAE/JME) is an uncommon form of genetic generalized epilepsy that appears as absence in childhood and evolves into generalized ... [more ▼]

Abstract : Childhood Absence Evolving to Juvenile Myoclonic Epilepsy (CAE/JME) is an uncommon form of genetic generalized epilepsy that appears as absence in childhood and evolves into generalized tonic–clonic seizures with myoclonic jerks during adolescence. In some family of patients affected by CAE/JME, mutations have been observed in the gene encoding for the transport protein importin-8 (IPO8). IPO8 could be at the origin of CAE/JME via its role in the transport of its targets (like Ago-2, Smad4, c-Jun). RT-qPCR has shown that IPO8 mRNA is expressed at all ages with no big difference in expression level. Using ISH, a clear expression of mIPO8 mRNA was observed in the sub-ventricular/ventricular zone (SVZ/VZ), the cortical plate (CP) and the ganglionic eminences (GE) of developing brain at E14. Both SVZ/VZ and GE are the “neurogenic niches” that generate glutamatergic and GABAergic neurons respectively. The implication of IPO8 in the generation of “glutamatergic neurons” was investigated by In Utero electroporation (IUE) and MGE Electroporation. Using shRNA, we observed that after 3 days, “glutamatergic neuroblasts” do not reach the CP in contrast to the control condition. This effect can be rescued by the co-expression of a form of IPO8 that is resistant to the shRNA. When overexpressing the pathological forms of hIPO8, but not a variant, migration of “glutamatergic neuroblasts” was also impaired. However, when the observation is made later, i.e. at P5, we observed that the neuroblasts finally reach their correct layer in the cortex, suggesting IPO8 only delayed but not blocked migration. Moreover, shRNA against IPO8 mRNA lead to alteration of interneurons (GABAergic neurons) migration same to overexpression of one mutated form of IPO8. Conclusion : IPO8 is expressed in mouse brain during development. It shows a clear expression during embryogenesis in the “neurogenic niches”. Moreover, IPO8 modulates neuroblasts (radial and tangential) migration in the developing brain. So, abnormal brain development due to IPO8 mutations could be at the origin of CAE/JME. [less ▲]

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See detailPraxis, besoins et impératifs affectifs : Réflexions sur la normativité de la conscience émue.
Recchia, Fabio ULiege

Conference (2017, April 26)

L'objectif de cette communication consiste à dégager les caractéristiques normatives de la conscience émue. Nous mobiliserons pour ce faire la thématique des "impératifs affectifs", qui est abondamment ... [more ▼]

L'objectif de cette communication consiste à dégager les caractéristiques normatives de la conscience émue. Nous mobiliserons pour ce faire la thématique des "impératifs affectifs", qui est abondamment discutée par Sartre dans "Les Racines de l'éthique". Sur cette base, nous développerons une réflexion en trois temps. 1° Nous situerons tout d'abord les "Racines de l'éthique" dans la continuité des réflexions de "l'Esquisse d'une théorie des émotions". 2° Nous montrerons ensuite que l'analyse des impératifs affectifs enveloppe une critique du positivisme, qui est une approche massivement adoptée par nombre de philosophie des émotions. 3° Enfin, nous approfondirons la description sartrienne des impératifs affectifs à partir de "L'Émile" de Jean-Jacques Rousseau. L'association de l'un et l'autre texte nous permettra en effet de commenter la "seconde forme d'émotion" qui est très allusivement décrite par les dernières pages de l'Esquisse d'une théorie des émotions. Plus largement, ce détour par la philosophie politique des modernes permettra d'établir un dialogue entre la phénoménologie sartrienne de l'affectivité et l'approche de la normativité qui est proposée par la philosophie française des sciences sociales. [less ▲]

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See detailGlobal approach for the validation of an in-line Raman spectroscopic method to determine the API content in real-time during a hot-melt extrusion process
Netchacovitch, Lauranne ULiege; Thiry, Justine ULiege; De Bleye, Charlotte ULiege et al

in Talanta (2017), 171

Since the Food and Drug Administration (FDA) published a guidance based on the Process Analytical Technology (PAT) approach, real-time analyses during manufacturing processes are in real expansion. In ... [more ▼]

Since the Food and Drug Administration (FDA) published a guidance based on the Process Analytical Technology (PAT) approach, real-time analyses during manufacturing processes are in real expansion. In this study, in-line Raman spectroscopic analyses were performed during a Hot-Melt Extrusion (HME) process to determine the Active Pharmaceutical Ingredient (API) content in real-time. The method was validated based on a univariate and a multivariate approach and the analytical performances of the obtained models were compared. Moreover, on one hand, in-line data were correlated with the real API concentration present in the sample quantified by a previously validated off-line confocal Raman microspectroscopic method. On the other hand, in-line data were also treated in function of the concentration based on the weighing of the components in the prepared mixture. The importance of developing quantitative methods based on the use of a reference method was thus highlighted. The method was validated according to the total error approach fixing the acceptance limits at ± 15% and the α risk at ± 5%. This method reaches the requirements of the European Pharmacopeia norms for the uniformity of content of single-dose preparations. The validation proves that future results will be in the acceptance limits with a previously defined probability. Finally, the in-line validated method was compared with the off-line one to demonstrate its ability to be used in routine analyses. [less ▲]

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See detailThe Matrix of Academic Organising. Articulating organisations’ 3Ds and academics’ logics of action
Dubois, Christophe ULiege; Dubois-Shaik, Farah

Scientific conference (2017, April 26)

The aim of this paper is twofold. It firstly aims to account for the Matrix of Excellence, Funding and Omnipresence characterizing academic organizations (Dubois-Shaik & Fusulier, 2016), and more ... [more ▼]

The aim of this paper is twofold. It firstly aims to account for the Matrix of Excellence, Funding and Omnipresence characterizing academic organizations (Dubois-Shaik & Fusulier, 2016), and more precisely their constitutive three dimensions: managerial discourse, formal and parallel structures (Friedberg, 2012; Dubois, 2014). Secondly, drawing on the metaphor of shadow organizing (Gherardi et al., 2017), we will illustrate some informal coping mechanisms occurring in the parallel structure of academic organizations. We will then discuss how these coping mechanisms are or are not being translated in managerial discourse and inscribed in formal structures. [less ▲]

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See detailBaromètre financier du secteur Transport et Logistique : évolution et perspectives
Lambert, Marie ULiege

Conference given outside the academic context (2017)

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See detailFirst retrievals of methane isotopologue, CH3D, from FTIR ground-based observations
Bader, Whitney ULiege; Strong, Kimberley; Walker, Kaley et al

Poster (2017, April 26)

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See detail4th Doctoral Seminar on Sustainability Research in the Built Environment Book of Abstracts
Attia, Shady ULiege; Teller, Jacques ULiege; Mahy, Grégory ULiege

Book published by SBD Lab (2017)

The DS2BE is a joint initiative of research groups working on sustainability issues at 8 Belgian universities: ULBruxelles, VUBrussel, KULeuven, UCLouvain, ULiège, UHasselt, UAntwerpen and UGent ... [more ▼]

The DS2BE is a joint initiative of research groups working on sustainability issues at 8 Belgian universities: ULBruxelles, VUBrussel, KULeuven, UCLouvain, ULiège, UHasselt, UAntwerpen and UGent. Conceived as a platform for PhD researchers whose work engages the built environment at different scales in the framework of sustainability, these seminars provide an excellent opportunity for the doctoral students of the partner institutions to present their ongoing research. They will get feedback from a broad panel of sustainability experts, including invited specialists and peers, for furthering their research. PhD candidates can provide submissions that concern topics, such as: - Sustainable Architecture and Resources, materials, re-cycling /re-use, building elements and envelope, building physics, building construction technology, building renovation, drawing lessons from vernacular, bioclimatic design, regenerative design, biomimetic and integrated design, …, - Sustainability theory, sustainability / environmental assessment at building and neighborhood scales, and at the scale of city and regions, - Sustainable urbanism, urban form, landscape and urban ecology, urban green infrastructure and ecosystem services, public space, density, urban infrastructure & transportation, water urbanism, retrofitting of buildings to the built environment, - Methodologically oriented PhDs focusing on issues related to LCA (Life Cycle Analysis), I-O (Input-Output Analysis), MFA (Material Flow Analysis), simulation techniques, to exploring urban metabolism, industrial ecology, environmental modelling, GIS-based land-use change modelling, to Research by Design. [less ▲]

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See detailConstitutus = καϑεστώς : un hellénisme de la langue juridique ?
Rochette, Bruno ULiege

Conference (2017, April 26)

Le participe parfait constitutus (ainsi que positus) a été vu comme une sorte de substitut destiné à pallier l’absence en latin de participe présent du verbe être (*ens, entis). Plusieurs auteurs ont ... [more ▼]

Le participe parfait constitutus (ainsi que positus) a été vu comme une sorte de substitut destiné à pallier l’absence en latin de participe présent du verbe être (*ens, entis). Plusieurs auteurs ont considéré cet emploi comme un hellénisme propre à la langue juridique en soulignant que, dans les Novellae de Justinien, constitutus est une traduction du grec καϑεστώς, qui a un sens actif. On en a déduit qu’il pourrait s’agir d’une particularité de la langue des juristes qui apparaît pour la première fois chez Julianus [4], Scaevola [6], Papinien [5] et Ulpien [8]. Cet emploi, qui ne semble pas antérieur à Sénèque [7], n’est toutefois pas spécifique aux juristes. On le rencontre dans le latin de l’Empire, spécialement chez des auteurs africains chrétiens et païens, comme Apulée [2] et Cyprien de Carthage [3], et surtout dans la langue tardive (Ammien Marcellin [1]). Cet usage pose la question de la spécificité de la langue des juristes et de l’influence éventuelle du grec sur cette langue technique. Une étude plus systématique des prétendus hellénismes chez le juriste Gaius, peut-être d’origine orientale, montre que l’influence du grec sur son latin, si elle a existé, est assez réduite. Un grand nombre de particularités qui ont été considérées comme des hellénismes sont en réalité des spécificités du latin tardif et connaissent des parallèles chez des auteurs comme Apulée, Tertullien, Augustin, Ammien Marcellin. J’étudie ici les emplois de constitutus comme prétendu substitut du participe présent de esse dans un corpus assez large de textes : Arnobe, Firmicus Maternus, Lactance, Hilaire, Lucifer, Ambroise, Jérôme, Sulpice Sévère, Cassien, Orose… jusqu’à Cassiodore. On trouve aussi cette tournure assez souvent dans la Vulgate. Pour expliquer cette spécificité, l’influence du grec n’est pas une donnée nécessaire. Il s’agit essentiellement, comme d’autres phénomènes, d’une évolution du latin, qui a sans doute éprouvé le besoin de combler la lacune de l’absence du participe présent du verbe « être », ce qui arrivera au Moyen Âge avec la création de *ens, entis, déjà proposé par Jules César. Exemples [1] Ammien Marcellin, XX, 3, 12 : eodem adhuc constituto [2] Apulée, Mét., IV, 11 : Tunc nos in ancipiti periculo constituti uel op primendi nostri uel deserendi socii remedium e re nata ualidum eo uolente comminiscimus. [3] Cyprien, Ep., 1, 1 : in clerico ministerio constituti [4] Julianus Dig. 24, 2, 6 : in captiuitate constitutus [5] Papinien Dig. 35, 1, 77, 3 : impubere filia constituta [6] Scaevola Dig. 4, 4, 39, 1 : curatoribus eius idoneis constitutis [7] Sénèque, NQ, III, 10, 3 : natura partes suas velut in ponderribus constitutas exanimat [8] Ulpien Dig. 3, 5, 19 : Ulpianus libro decimo ad edictum. sin autem apud hostes constitutus decessit, et successori et aduersus successorem eius negotiorum gestorum directa et contraria competit. Bibliographie GARCEA A., Caesar’s De analogia. Edition, Translation, and Commentary, Oxford, 2012. KALB W., Das Juristenlatein. Versuch einer Charakteristik auf Grundlage der Digesten, Nürnberg 1888 [Aalen 1961] --, Roms Juristen nach ihrer Sprache dargestellt, Leipzig 1890 [Aalen 1975]. LÖFSTEDT E., Zur Frage der Gräzismen, dans Syntactica. Studien und Beiträge zur historischen Syntax des Lateins II, Lund 1933, 406-457 NELSON H.L.W., Überlieferung, Aufbau und Stil von Gai Institutiones (Studia Gaiana, 6), Leiden 1981, ROSÉN H.-D. SHLEV, QUASI: Its Grecizing [?] syntactic patterns, Colloque de Linguistique latine de Toulouse (sous presse). SCHRIJNEN J.-CHR. MOHRMANN, Studien zur Sprache der Briefe des hl. Cyprian, 2 vol., Nijmegen 1934 [less ▲]

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See detailInterviews on Residential Building Stock Deep Renovation in Belgium
Ruellan, Guirec ULiege

Poster (2017, April 26)

Belgium should increase the deep renovation rate of existing residential building stock at least to 3% a year to achieve the EU objectives of decreasing by 80% the Green House Gas Emissions before 2050 ... [more ▼]

Belgium should increase the deep renovation rate of existing residential building stock at least to 3% a year to achieve the EU objectives of decreasing by 80% the Green House Gas Emissions before 2050. Since the first thermal legislations (between 1985 and 2000, depending on the Region), efficiency and comfort of newly built houses have met higher standards. But the renovation rate of residential buildings remained stable in the last 20 years. Only 25000 renovation permits are issued each year, in which a small amount of them are highly energy efficient. Literature review has showed that drivers and barriers of deep renovation are many and varied, sometimes contradictory and often underestimated. Conducted interviews with experts who study different facet of renovation present some others viewpoints on this subject. According to their own specific experience, each interviewee thinks differently on possible solutions. The poster set out the interview analysis. Some points are very close to the literature review, such as the environmental and economic issues of the residential renovation, while other results are solely extracted based on the interviews’ results. Amongst others, the necessity to maintain and improve the existing building stock to new standards takes an important place. The regulation appears to be a good driver as much as a barrier, depending on the local legislations and buildings context particularly in Belgium where the diversity of the building stock is very important. Public policies seem to be the first tools to unlock the renovation rate even if the development of new financial model and the information of stakeholders are also highlighted. This analysis increases the comprehension of the renovation topic on a new level, including some adjacent ideas that lead to better understanding of the existing barriers and possible strategies to overtake them, so that to involve everyone in the renovation strategy definition to promote the most efficient one. [less ▲]

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See detailDiabetes and the kidney disease risk
Krzesinski, Jean-Marie ULiege

Conference (2017, April 26)

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See detailA method for encoding Egyptian quadrats in Unicode
Glass, Andrew; Hafemann, Ingelore; Nederhof, Mark-Jan et al

Computer development (2017)

The proposal to encode three control characters for Egyptian Hieroglyphs was accepted at the February 2016 UTC meeting. Following that acceptance some members of the Egyptological community raised ... [more ▼]

The proposal to encode three control characters for Egyptian Hieroglyphs was accepted at the February 2016 UTC meeting. Following that acceptance some members of the Egyptological community raised concerns that the accepted controls were insufficient for their requirements. This led to a series of discussions and document submissions between specialists and implementers that explored the issues relating to encoding the quadrat structures that are an inherent feature of Egyptian Hieroglyphic writing. The present document combines expert input on Egyptian Hieroglyphs and a detailed exploration of possible solutions. It does not attempt to summarize or repeat arguments and details from earlier documents. Cross-references to earlier submissions are provided where appropriate. The result is a draft proposal for a system of controls that will enable plain text encoding of Egyptian Hieroglyphs in quadrats. [less ▲]

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See detailShape-memory polymers: principles and applications
Defize, Thomas ULiege

Scientific conference (2017, April 26)

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