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See detailLe jeu vidéo comme objet de recherche
Barnabé, Fanny ULg

Scientific conference (2015, January 26)

Présentation du jeu vidéo en tant qu'objet de recherche et de l'histoire des game studies, avec un accent mis sur la question de la narration et sur le rôle qu'elle a joué dans la structuration du champ.

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See detailOncologie et revalidation physique
Leclerc, Anne-France ULg; Foidart-Dessalle, Marguerite ULg; COUCKE, Philippe ULg et al

in Abstract Book du Colloque "Femmes et Santé" (Université d'Hiver) (2015, January 26)

Le cancer constitue une maladie fréquente en Belgique puisqu'un homme sur trois et une femme sur quatre sont confrontés à la maladie avant l'âge de septante-cinq ans (Fondation Registre du Cancer, 2008 ... [more ▼]

Le cancer constitue une maladie fréquente en Belgique puisqu'un homme sur trois et une femme sur quatre sont confrontés à la maladie avant l'âge de septante-cinq ans (Fondation Registre du Cancer, 2008). La détection précoce et l'amélioration des traitements du cancer, généralement une combinaison de chirurgie, radiothérapie, chimiothérapie, hormonothérapie et thérapie ciblée, ont permis une augmentation du taux de survie. Cependant, ces traitements peuvent être à l'origine de nombreux effets secondaires, non seulement précoces, mais également tardifs, réduisant la qualité de vie. De nombreux programmes de réhabilitation après cancer sont basés sur la psychothérapie et le support social uniquement, or ceux-ci n'agissent généralement pas sur les problèmes physiques encourus par les patients tels que la fatigue, la prise de poids et la diminution des capacités fonctionnelles. C'est pourquoi nous émettons l'hypothèse qu'une revalidation physique, associée à des séances psycho-éducatives et constituant ainsi une prise en charge multidisciplinaire, permettrait d'améliorer d'autant plus la qualité de vie et le bien-être tant physique que psychologique des patients ayant été traités pour un cancer. [less ▲]

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See detailL'observation des interactions précoces mère-bébé ultérieurement diagnostiqué autsite
Boulard, Aurore ULg

Conference given outside the academic context (2015)

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See detailTargeting osteopontin suppresses glioblastoma stem-like cell character and tumorigenicity in vivo
Lamour, Virginie; Henry, Aurélie ULg; Kroonen, Jerome et al

in International Journal of Cancer = Journal International du Cancer (2015)

Osteopontin (OPN) is a secreted protein involved in most aspects of tumor progression and metastasis development. Elevated OPN expression has been reported in multiple types of cancer including ... [more ▼]

Osteopontin (OPN) is a secreted protein involved in most aspects of tumor progression and metastasis development. Elevated OPN expression has been reported in multiple types of cancer including glioblastoma (GBM), the highest grade and most aggressive brain tumor. GBMs contain a subpopulation of glioma-initiating cells (GICs) implicated in progression, therapeutic resistance and recurrence. We have previously demonstrated that OPN silencing inhibited GBM cell growth in vitro and in vivo. Moreover, activation of CD44 signaling upon OPN ligation has been recently implicated in the acquisition of a stem cell phenotype by GBM cells. The present study is aimed to explore OPN autocrine function using shRNA silencing strategy in GICs enriched from GBM cell lines and a human primary GBM grown in EGF and bFGF defined medium. The removal of these growth factors and addition of serum induced a significant loss of OPN expression in GICs. We showed that OPN-silenced GICs were unable to grow as spheres and this capacity was restored by exogenous OPN. Importantly, the expression of Sox2, Oct3/4 and Nanog, key stemness transcription factors, was significantly decreased in GICs upon OPN targeting. We identified Akt/mTOR/p70S6K as the main signaling pathway triggered following OPN-mediated EGFR activation in GICs. Finally, in an orthotopic xenograft mouse model, the tumorigenic potential of U87-MG sphere cells was completely abrogated upon OPN silencing. Our demonstration of endogenous OPN major regulatory effects on GICs stemness phenotype and tumorigenicity implies a greater role than anticipated for OPN in GBM pathogenesis from initiation and progression to probable recurrence. [less ▲]

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See detailComprendre la voix et Comment optimaliser sa voix
Morsomme, Dominique ULg; Remacle, Angélique ULg

Conference given outside the academic context (2015)

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See detailA novel sub-phylum method discriminates better the impact of crop management on soil microbial community
Degrune, Florine ULg; Dufrêne, Marc ULg; Colinet, Gilles ULg et al

in Agronomy for Sustainable Development (2015)

Soil microorganisms such as mycorrhizae and plant-growth-promoting rhizobacteria have beneficial effects on crop productivity. Agricultural practices are known to impact soil microbial communities, but ... [more ▼]

Soil microorganisms such as mycorrhizae and plant-growth-promoting rhizobacteria have beneficial effects on crop productivity. Agricultural practices are known to impact soil microbial communities, but past studies examining this impact have focused mostly on one or two taxonomic levels, such as phylum and class, thus missing potentially relevant information from lower levels. Therefore we propose here an original, sub-phylum method for studying how agricultural practices modify microbial communities. This method involves exploiting the available sequence information at the lowest taxonomic level attainable for each operational taxonomic unit. In order to validate this novel method we assessed microbial community composition using 454 pyrosequencing of 16S and 28S rRNA genes, then we compared the results with results of a phylum-level analysis. Agricultural practices included conventional tillage, reduced tillage, residue removal and residue retention. Results show that, at the lowest taxonomic level attainable, tillage is the main factor influencing both bacterial community composition, accounting for 13% of the variation, and fungal community composition, accounting for 18% of the variation. Whereas phylum-level analysis failed to reveal any effect of soil practice on bacterial community composition, and missed the fact that different members of the same phylum responded differently to tillage practice. For instance, the fungal phylum Chytridiomycota showed no impact of soil treatment, while sub-phylum-level analysis revealed an impact of tillage practice on the Chytridiomycota sub-groups Gibberella, which includes a notorious wheat pathogen, and Trichocomaceae. This clearly demonstrates the necessity of exploiting the information obtainable at sub-phylum level when assessing the effects of agricultural practice on microbial communities. [less ▲]

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See detailREQUACARTO : outil d'aide à l'échantillonnage et au conseil de fumure
Renneson, Malorie ULg

Conference (2015, January 23)

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See detailL'ISIPCA comme terrain ethnographique
Vangeebergen, Thomas ULg

Conference given outside the academic context (2015)

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See detailMucoadhesive cellulosic derivative sponges as drug delivery system for vaginal application
Furst, Tania ULg; Piette, Marie ULg; Lechanteur, Anna ULg et al

in European Journal of Pharmaceutics & Biopharmaceutics (2015)

Vaginal delivery of active drugs has been largely studied for local and systemic applications. It is well known that vagina is a complex route, due to physiological and non-physiological changes ... [more ▼]

Vaginal delivery of active drugs has been largely studied for local and systemic applications. It is well known that vagina is a complex route, due to physiological and non-physiological changes. Therefore, in order to achieve a prolonged local effect, these variations have to be considered. The aim of this study was to formulate and to characterize a solid system, called sponges, obtained by lyophilization of cellulosic derivative (HEC 250M) hydrogels. These sponges have to meet particular criteria to be adapted for vaginal application: they have to adhere to the vaginal cavity and to be rehydrated by the small amount of vaginal fluids. Moreover, they have to be easily manipulated and to be stable. Three freezing temperatures have been tested to prepare sponges ( 15 C, 25 C, 35 C). By SE analyzes, it was observed that the pores into the sponges were smaller and numerous as the freezing temperature decreases. However, this temperature did not have any influence on the rehydration speed that was rather influenced by the HEC concentration. Viscosity and mucoadhesive strength of hydrogels and corresponding sponges were also measured. It appeared that these parameters are mainly dépendent on the HEC concentration. These mucoadhesive sponges can be considered as potential drug delivery systems intended for vaginal application. [less ▲]

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See detailSick Building Syndrome : Analyse et prévention
Romain, Anne-Claude ULg

Scientific conference (2015, January 22)

Le SBS se caractérise par un ou plusieurs symptômes non spécifiques touchant la peau, les muqueuses, le système respiratoire et/ou le système nerveux central. Ces symptômes apparaissent rapidement lorsque ... [more ▼]

Le SBS se caractérise par un ou plusieurs symptômes non spécifiques touchant la peau, les muqueuses, le système respiratoire et/ou le système nerveux central. Ces symptômes apparaissent rapidement lorsque des personnes séjournent dans un bâtiment et s’estompent, voire le plus souvent disparaissent, dès qu’elles le quittent, le soir, le week end ou durant les vacances. Ils sont donc indéniablement liés à l’occupation des locaux. Le SBS a été défini par l’Organisation Mondiale de la Santé ou OMS en 1983 qui en 1984 a évalué à 30% des bâtiments nouveaux ou rénovés le taux de « sick buildings ». Les symptômes a long terme incluent les allergies et l’asthme, certains cancers, des maladies auto-immunes ou neurodégénératives. POINTS ABORDES • Définition du SBS • Analyse des sources de contamination indoor • Solutions pour réduire la contamination indoor • Actions préventives OBJECTIFS • Comprendre le SBS, ses expressions • Identifier les sources d’inconfort • Pouvoir anticiper et solutionner les problèmes sources d’inconfort [less ▲]

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See detailThe VLTI/PIONIER near-infrared interferometric survey of southern T Tauri stars. I. First results
Anthonioz, F.; Menard, F.; Pinte, C. et al

in Astronomy and Astrophysics (2015), 574

Context. The properties of the inner disks of bright Herbig AeBe stars have been studied with near-infrared (NIR) interferometry and high resolution spectroscopy. The continuum (dust) and a few molecular ... [more ▼]

Context. The properties of the inner disks of bright Herbig AeBe stars have been studied with near-infrared (NIR) interferometry and high resolution spectroscopy. The continuum (dust) and a few molecular gas species have been studied close to the central star; however, sensitivity problems limit direct information about the inner disks of the fainter T Tauri stars. <BR /> Aims: Our aim is to measure some of the properties (inner radius, brightness profile, shape) of the inner regions of circumstellar disk surrounding southern T Tauri stars. <BR /> Methods: We performed a survey with the VLTI/PIONIER recombiner instrument at H-band of 21 T Tauri stars. The baselines used ranged from 11 m to 129 m, corresponding to a maximum resolution of ~3 mas (~0.45 au at 150 pc). <BR /> Results: Thirteen disks are resolved well and the visibility curves are fully sampled as a function of baseline in the range 45-130 m for these 13 objects. A simple qualitative examination of visibility profiles allows us to identify a rapid drop-off in the visibilities at short baselines(<10 Mlambda) in 8 resolved disks. This is indicative of a significant contribution from an extended (R> 3 au, at 150 pc) contribution of light from the disk. We demonstrate that this component is compatible with scattered light, providing strong support to an earlier prediction. The amplitude of the drop-off and the amount of dust thermal emission changes from source to source suggesting that each disk is different. A by-product of the survey is the identification of a new milli-arcsec separation binary: WW Cha. Spectroscopic and interferometric data of AK Sco have also been fitted with a binary + disk model. <BR /> Conclusions: The visibility data are reproduced well when thermal emission and scattering from dust are fully considered. The inner radii measured are consistent with the expected dust sublimation radii. The modelling of AK Sco suggests a likely coplanarity between the disk and the binary's orbital plane. [less ▲]

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See detailDesign Space for Analytical Methods: Why ? What ? How ?
Rozet, Eric ULg; Debrus, Benjamin ULg; Lebrun, Pierre ULg et al

Conference (2015, January 22)

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See detailSystème européen des comptes (SEC) et finances publiques locales
Piron, Damien ULg

Conference given outside the academic context (2015)

Detailed reference viewed: 37 (4 ULg)
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See detailLa sociologie au risque de l'environnement
Mormont, Marc ULg

Scientific conference (2015, January 22)

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See detailThe potential impact of animal protein intake on global and central obesity: evidence from the ORISCAV-LUX study
Alkerwi, A.; Sauvageot, Nicolas ULg; Buckley, J.D. et al

in Public Health Nutrition (2015)

Detailed reference viewed: 42 (8 ULg)
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See detailEpidémiologie de la lithiase urinaire
Castiglione, Vincent ULg; GADISSEUR, Romy ULg

Conference (2015, January 22)

Description de l'épidémiologie de lithiase urinaire en Province de Liège, comparaison avec différents pays (France, USA), études récentes, explications sur des facteurs de risque.

Detailed reference viewed: 12 (2 ULg)
See detailLe rôle des structures et des modèles pour la traduction
Smette, Bernard ULg

Scientific conference (2015, January 22)

Depuis au moins quelques dizaines d'années, on constate une dissémination du terme de « traduction » au-delà du domaine de la traductologie, ou des translation studies, pour qualifier un certain nombre d ... [more ▼]

Depuis au moins quelques dizaines d'années, on constate une dissémination du terme de « traduction » au-delà du domaine de la traductologie, ou des translation studies, pour qualifier un certain nombre d'outils méthodologiques « disparates » en usage dans différents champs du savoir et de la culture. Cette exportation de la « traduction » s'est notamment opérée vers la philosophie des sciences où plusieurs chercheurs ont cherché, à partir de cette notion, à rendre compte d'un certain nombre d'enjeux épistémologiques propres à leur domaine de recherche. On peut constater que cette importation du terme de « traduction » au sein d'un domaine particulier donne à voir différentes articulations conceptuelles entre ce terme et un certain nombre d'autres notions. Or, un moyen de comprendre un concept passe, notamment, par l'identification du champ conceptuel dans lequel il s'insère. Concernant la traduction, et chez des auteurs comme W.V.O. Quine et M. Serres qui sont exemplaires de l'importation de cette notion en épistémologie et en philosophie des sciences, on peut constater qu'elle s'inscrit dans des champs conceptuels dans lesquels figure de manière significative la notion de « structure ». Cette communication aura donc pour objectif d'esquisser les grandes lignes de cette articulation entre « traduction » et « structure » chez ces deux philosophes. On peut, en effet, raisonnablement penser que de l'éclairage de cette articulation découlera un certain nombre d'hypothèses qui pourront aider à comprendre les raisons qui permettent de faire usage de la notion de traduction en dehors de la traductologie. [less ▲]

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See detailLes Latino Américaines en Belgique: Qui sont-elles? Quelles sont leurs stratégies?
Vivas Romero, Maria ULg; Camargo, Beatriz

Scientific conference (2015, January 22)

Detailed reference viewed: 18 (4 ULg)