Last 7 days     Results 2521-2540 of 68607.   122 123 124 125 126 127 128 129 130 131 132   The nationalization of local elections: disentangling effects of voters’ demand and party’s organizational capacityDodeigne, Jérémy ; Jacquet, Vincent; Reuchamps, MinConference (2017, April 03)Detailed reference viewed: 10 (1 ULg) Quaternary prevention, the art of “primum non nocere”Jamoulle, Marc Conference (2017, April 03)State of the art of the concept of Quaternary preventionDetailed reference viewed: 71 (1 ULg) Le patriotisme économique : nationalisme banal et communauté imaginéeClaisse, Frédéric Conference (2017, April 03)Revenant sur les appels à la « fierté collective », au « patriotisme économique » et au « nationalisme d’ouverture » réitérés par les derniers Ministres-Présidents à la tête de la Wallonie, la ... [more ▼]Revenant sur les appels à la « fierté collective », au « patriotisme économique » et au « nationalisme d’ouverture » réitérés par les derniers Ministres-Présidents à la tête de la Wallonie, la communication s’attache à montrer comment ces tentatives de revitalisation d’un sentiment d’attachement identitaire, tout en relevant des manifestations du « nationalisme banal » (M. Billig), entretiennent le déficit d’imaginaire régional, réduit au développement de la « marque Wallonie » et de sa promotion auprès de ses habitants et des investisseurs. L’insistance sur la seule valeur économique et instrumentale de la communauté, visant à améliorer la compétitivité de la région sur son marché global et intérieur, fait d’autant mieux ressortir, par contraste, la dimension narrative sous-jacente à l’imagination nationaliste, particulièrement mise en évidence dans la nouvelle économie de l’enrichissement (L. Boltanski et A. Esquerre), fondée sur la patrimonialisation et l’exploitation du passé comme gisement de valeur. Du croisement des deux axes ainsi dégagés (nationalisme de faible ou forte intensité ; recours plus ou moins appuyé au storytelling), émerge une conception élargie du nationalisme, qui en fait apparaître de nouvelles modalités et permet d’ouvrir à une autre compréhension de doctrines comme le national-libéralisme ou le projet post-national. Dans la continuité des observations de M. Billig, notre cadre d'analyse structurale tend à faire des mouvements nationalistes (au sens le plus courant du terme dans l’analyse politique) un simple cas particulier parmi d’autres modes de participation plus ordinaires, infra-conscientes et naturalisées, à la communauté nationale. [less ▲]Detailed reference viewed: 30 (0 ULg) Themes related to prevention in the Q-Codes taxonomy. Call to a collaborative exploration into the abstracts of Europrev meetingsJamoulle, Marc Conference (2017, April 03)Background For the documentation of the clinical data, the International Classification of Primary Care (ICPC-2) is used, often in conjunction with the more granular International Classification of ... [more ▼]Background For the documentation of the clinical data, the International Classification of Primary Care (ICPC-2) is used, often in conjunction with the more granular International Classification of Diseases (ICD). For retrieval of scientific bibliographic information in GP/FM, Medical Subject Headings (MeSH) are used. With over 25,000 available MeSH descriptors, indexing is not easy, and yet not all aspects of the broad field of GM/FM are covered . ICPC-2 has been developed to identify reasons for encounter, symptoms, acts performed or requested and diagnosis in daily practice: It captures clinical encounters for epidemiological research. But, it was not constructed to reflect the non-clinical aspects of the profession, such as organizational, managerial, educational, and investigational aspects. Recently, a new taxonomy of organizational aspect of GM/FM has been developed to ameliorate this situation. The purpose of this development was to provide tools to exploit modern technology in terminology for information storage and retrieval systems , such as machine learning, semantic web techniques and natural language processing (NLP). The 182 concepts identified were thoroughly described in terminology records, which are freely accessible on the web (www.hetop.eu/Q). All concept and definitions were translated into 8 languages and are available online. (http://3cgp.woncaeurope.org). A book is available in 6 languages To develop the Q-codes 1700 abstracts of GP/FM congresses have been carefully analyzed. This has been the basis of the work. As a team of the EGRPN has also analyzed 600 EGPRN abstracts and developed a taxonomy of research, I have this work has been incorporated to update the QR domain. Thus ongoing Q-Codes are based on the analysis of 2300 abstracts The most important fact is that there is a Q-Codes only if the theme has been discussed by physicians during congresses. This is a bottom-up approach which contrast with the expert approach of the authors of textbook The Q-Codes have been integrated with the clinical classification ICPC-2 into a coherent whole, under the name Core Content of General Practice and Family Medicine (3CGP), for further enhancement of medical documentation and indexing of GP/FM master thesis and congress abstracts The value of a taxonomy is determined by the quality and speed of the maintenance and updating process. This will be handled by a working group of the Wonca International Classification Committee (WICC) (www.ph3c.org/Q) already authors of ICPC-2. Aim to present the preventive aspects of the Q-codes, a taxonomy specifically directed to describe the managerial aspects of GP/FM. To make a call to Europrev members to come an board of the Q-codes working group and to help to make more accurate the preventive fields in the Q-Codes taxonomy download abstract below [less ▲]Detailed reference viewed: 123 (6 ULg) Stable GPR101 over-Expressing Cell Lines As an Invaluable Tool for Functional Studies, Ligand Screening, and the Identification of Deregulated Genes/Pathways in Patients with X-Linked AcrogigantismTrivellin, Giampaolo; Janjic, Maria; Larco, Darwin et alPoster (2017, April 02)Background: GPR101 is an orphan G protein-coupled receptor (GPCR) that is duplicated in patients with X-linked acrogigantism (X-LAG) and over-expressed in their GH- and PRL-secreting tumors. GPR101 is a ... [more ▼]Background: GPR101 is an orphan G protein-coupled receptor (GPCR) that is duplicated in patients with X-linked acrogigantism (X-LAG) and over-expressed in their GH- and PRL-secreting tumors. GPR101 is a constitutively active GPCR that strongly activates the cAMP pathway. To elucidate the mechanisms through which GPR101 causes GH over-secretion we generated HEK293 and GH/PRL-secreting (GH3) cells with stable GPR101 expression. Methods: Both cell lines were created via direct integration of a human GPR101-coding sequence into their genome. In HEK293 cells this was achieved by transient transfection of a GPR101-expressing plasmid, while GH3 were transduced with GPR101 lentiviral particles. Cells were selected with appropriate antibiotics and the surviving clones expanded. GPR101 expression was quantified by RT-qPCR and immunofluorescence/western blotting. Cell proliferation (MTT assay), cAMP levels (125I-labeled cAMP tracer), and calcium signaling (FURA 2 AM) were determined. RNA was extracted from both cell lines and subjected to RNA-seq. Differential gene expression between control and GPR101-expressing cells and pathway analysis was carried out with the Stirplate and MetaCore softwares, respectively. De-regulated genes were validated by RT-qPCR. Results: High GPR101 expression was achieved in both cell lines and confirmed at the mRNA and protein level. GPR101-expressing cells proliferated at different rates from the respective controls: GPR101-HEK293 cells were slow-dividing, while GPR101-GH3 divided faster. cAMP production was enhanced in GPR101-GH3 and accompained by increased excitability of cells. Differential expression analysis in HEK293 cells revealed several up-regulated and few down-regulated genes. Among the genes with high expression, several were linked to the cAMP pathway: CGA, PCK1, LINC00473 and PDE3A. Enrichment analysis ranked cytoskeleton remodeling and cell cycle regulation (inhibition of G1/S transition) as the most relevant pathways. In GH3 cells most of the genes with a significantly different expression encoded for membrane-localized proteins, among which were ion channels (Trpm8, Kcnj1), GPCRs (Trhr), and calcium sensors (Syt4, Anxa1). Biological processes associated with these genes are: vesicle transport and fusion, cytoskeleton organization, and energy homeostasis. Conclusions: These results show that the intrinsic activity of GPR101 strongly stimulates cAMP production and this in turn facilitates voltage-gated calcium influx. Changes in cAMP/calcium signaling are accompanied with faster/slower cell division depending on the cell type. Accordingly, several genes associated with these and related pathways are differentially expressed. The establishment of these cell lines will be of paramount importance to validate putative GPR101 ligands and to conduct functional studies. [less ▲]Detailed reference viewed: 57 (2 ULg) From parts to whole and back again. The emblem system in the French Jesuit FestivalsDe Marco, Rosa in Höpel, Ingrid; McKeown, Simon (Eds.) Emblems and Impact Volume II Von Zentrum und Peripherie der Emblematik. Selected Proceedings of the 10th International Conference of the Society for Emblem Studies (2017, April 01)Detailed reference viewed: 62 (15 ULg) I viaggi di studio: una risorsa per accompagnare il lavoro educativoPirard, Florence Conference (2017, April 01)Quand ils sont inscrits dans des dispositifs d’accompagnement organisés en réseau et ancrés dans les pratiques professionnelles, on peut faire l’hypothèse que les voyages d’étude contribuent à une ... [more ▼]Quand ils sont inscrits dans des dispositifs d’accompagnement organisés en réseau et ancrés dans les pratiques professionnelles, on peut faire l’hypothèse que les voyages d’étude contribuent à une transformation à la fois des acteurs qui découvrent d’autres manières de penser et d’agir et des actions qu’ils sont susceptibles d’améliorer. Ils s’inscrivent dans des dispositifs qui relèvent d’une culture de la professionnalisation et se démarquent d'autres types d'actions formatives inscrites dans les cultures de l'enseignement et de la formation. Ils constituent des opportunités d'apprentissage professionnels en situation informelles. La conférence questionne la place du voyage d’étude dans la formation des professionnel-le-s de l'enfance, les conditions de sa mise en œuvre et les effets observés sur les pratiques professionnelles. [less ▲]Detailed reference viewed: 22 (4 ULg) A probabilistic multifactorial approach to the nature of contact-induced change: A case-study on English substitutive complex prepositionsBéchet, Christophe Conference (2017, April 01)Detailed reference viewed: 25 (1 ULg) WASP-167b/KELT-13b: Joint discovery of a hot Jupiter transiting a rapidly-rotating F1V starTemple, L. Y.; Hellier, C.; Albrow, M. D. et alin Monthly Notices of the Royal Astronomical Society (2017), 471(3), 2743-2752We report the joint WASP/KELT discovery of WASP-167b/KELT-13b, a transiting hot Jupiter with a 2.02-d orbit around a $V$ = 10.5, F1V star with [Fe/H] = 0.1 $\pm$ 0.1. The 1.5 R$_{\rm Jup}$ planet was ... [more ▼]We report the joint WASP/KELT discovery of WASP-167b/KELT-13b, a transiting hot Jupiter with a 2.02-d orbit around a $V$ = 10.5, F1V star with [Fe/H] = 0.1 $\pm$ 0.1. The 1.5 R$_{\rm Jup}$ planet was confirmed by Doppler tomography of the stellar line profiles during transit. We place a limit of $<$ 8 M$_{\rm Jup}$ on its mass. The planet is in a retrograde orbit with a sky-projected spin-orbit angle of $\lambda = -165^{\circ} \pm 5^{\circ}$. This is in agreement with the known tendency for orbits around hotter stars to be more likely to be misaligned. WASP-167/KELT-13 is one of the few systems where the stellar rotation period is less than the planetary orbital period. We find evidence of non-radial stellar pulsations in the host star, making it a $\delta$-Scuti or $\gamma$-Dor variable. The similarity to WASP-33, a previously known hot-Jupiter host with pulsations, adds to the suggestion that close-in planets might be able to excite stellar pulsations. [less ▲]Detailed reference viewed: 12 (4 ULg) La poésie à Liège : d'Izoard et Jacqmin à nos joursPurnelle, Gérald Article for general public (2017)Detailed reference viewed: 16 (5 ULg) L’esprit de Cîteaux : des femmes et des hommes pour en vivreHenneau, Marie-Elisabeth Conference (2017, April 01) Asymptotic behavior of regular sequencesLeroy, Julien Scientific conference (2017, April)Detailed reference viewed: 7 (1 ULg) Out of the ground: two coexisting fossorial toad species differ in their emergence and movement patternsSzékely, Diana ; Cogalniceanu, Dan; Székely, Paul et alin Zoology (2017), 121Understanding the way species with similar niches can coexist is a challenge in ecology.The niche partitioning hypothesis has received much support, positing that species can exploit available resources ... [more ▼]Understanding the way species with similar niches can coexist is a challenge in ecology.The niche partitioning hypothesis has received much support, positing that species can exploit available resources in different ways. In the case of secretive species, behavioural mechanisms of partitioning are still poorly understood. This is especially true for fossorial frogs because individuals hide underground by day and are active only during the night. We investigated the nocturnal activity and tested the niche partitioning hypothesis in two syntopic fossorial spadefoot toads (Pelobates fuscus and P. syriacus) by examining interspecific variation in emergence from the soil. We employed a night vision recording system combined with video-tracking analyses in a replicated laboratory setting to quantify individual movement patterns, a procedure that has not been used until now to observe terrestrial amphibians. Most individuals appeared on the surface every night and returned to their original burrow (about 60% of the times), or dug a new one around morning. There was a large temporal overlap between the two species. However, P. syriacus was significantly more active than P. fuscus in terms of total distance covered and time spent moving, while P. fuscus individuals left their underground burrow more frequently than P. syriacus. Consequently, P. fuscus adopted more of a sit-and-wait behaviour compared to P. syriacus, and this could facilitate their coexistence. The use of night video-tracking technologies offered the advantage of individually tracking these secretive organisms during their nocturnal activity period and getting fine-grain data to understand their movement patterns. [less ▲]Detailed reference viewed: 62 (24 ULg) Signification et notification en Europe Entre efficacité et droits de la défenseWautelet, Patrick Conference (2017, April)Cette présentation a comme objectif d'offrir un aperçu de la jurisprudence de la Cour de justice relative au Règlement 1393/2007Detailed reference viewed: 37 (2 ULg) Interest of creatine supplementation insoccerMiny, Kevin ; Burrowes, J; Jidovtseff, Boris in Science & Sports (2017), 32(2), 61-72Objectives This review article aimed to summarize the current state of understanding on creatine supplementation for soccer players. In other words, it investigated the beneficial (and potentially ... [more ▼]Objectives This review article aimed to summarize the current state of understanding on creatine supplementation for soccer players. In other words, it investigated the beneficial (and potentially negative) effects of this supplementation on sport-specific skills and performance in soccer players. Furthermore, this article accordingly discussed the safest and most recommended protocols for the consumption of creatine by these athletes. News Studies have shown that creatine supplementation can have positive effects on sprint and vertical jump performances in soccer players. This supplementation may also enhance soccer players’ muscle strength and adaptation to a high-intensity training regimen. Besides, creatine may be able to enhance muscle glycogen (as well as phosphocreatine) storage, reduce oxidative stress, and improve muscular repair and hypertrophy. Interestingly, creatine supplementation does not seem to affect aerobic performance. Prospects and projects Soccer players could take creatine during pre-season training (3 to 5g/day) in order to help them endure a high-intensity training regimen and enhance their muscular strength and adaptation resulting from strength and/or resistance training. A lower dosage (less than 3g/day) might also be sufficient and beneficial during the season in case of fatigue, in order to sustain adequate levels of phosphocreatine and glycogen in the muscles. Occasional intakes (about 3g) before games and/or extenuating practices could also give a physical and mental boost to the players. Conclusion Most of the studies measured the effects of creatine on skills or physical performances in isolation from the true athletic demands of soccer match play. In conclusion, there is still a need for more research in order to determine whether creatine supplementation is ergogenic regarding the (aerobic) capacity to repeat (very) high-intensity actions, more particularly during competitive soccer. [less ▲]Detailed reference viewed: 54 (9 ULg) Impact of tillage on greenhouse gas emissions by an agricultural crop and dynamics of N2O fluxes: Insights from automated closed chamber measurementsLognoul, Margaux ; Theodorakopoulos, Nicolas ; Hiel, Marie-Pierre et alin Soil & Tillage Research (2017), 167Our experiment aimed at studying the impact of long term tillage treatments – reduced tillage (RT) and conventional tillage (CT), on CO2 and N2O emissions by soil and at describing the dynamics of N2O ... [more ▼]Our experiment aimed at studying the impact of long term tillage treatments – reduced tillage (RT) and conventional tillage (CT), on CO2 and N2O emissions by soil and at describing the dynamics of N2O fluxes. Gas measurements were performed from June to October 2015 in a Belgian maize crop, with homemade automated closed chambers, allowing continuous measurement at a high temporal resolution. After 7 years of treatment, CO2 and N2O average emissions were significantly larger in the RT parcel than in the CT parcel. This observation was attributed to the effect of tillage on the distribution of crop residues within the soil profile, leading to higher soil organic C and total N contents and a greater microbial biomass in the upper layer in RT. A single N2O emission peak triggered by a sudden increase of water- filled pore space (WFPS) was observed in the beginning of the measuring campaign. The absence of large emission afterwards was most likely due to a decreasing availability of N as crop grew. N2O background fluxes showed to be significantly correlated to CO2 fluxes but not to WFPS, while the influence of soil temperature remained unclear. Our results question the suitability of reduced tillage as a “climate-smart” practice and suggest that more experiments be conducted on conservation practices and their potent negative effect on environment. [less ▲]Detailed reference viewed: 120 (41 ULg) Work environment and work-to-family conflict: Mediating role of work investment.Babic, Audrey ; Stinglhamber, Florence; Barbier, Marie et alPoster (2017, April)Detailed reference viewed: 23 (2 ULg) De l'imposture à l'atittude éducative dans le domaine de l'Education Thérapeutique du PatientPétré, Benoît Conference (2017, April)Detailed reference viewed: 37 (4 ULg) Lessons learned from combined experimental and numerical modelling of urban ﬂoodsArchambeau, Pierre ; Bruwier, Martin ; Finaud-Guyot, Pascal et alConference (2017, April)Field data for validating hydraulic models remain scarce, They are often limited to inundation extents and water marks, which provide little insights into the dynamic features of the ﬂow in urbanized ... [more ▼]Field data for validating hydraulic models remain scarce, They are often limited to inundation extents and water marks, which provide little insights into the dynamic features of the ﬂow in urbanized ﬂoodplains, such as the discharge partition in-between the streets and the velocity ﬁelds. To address this issue, a unique experimental setup representing a whole urban district was built in the laboratory ICube in Strasbourg and the state-of-the-art shallow- water model Wolf 2D was tested against the experimental measurements (An'ault et al, 2016), The numerical model was also used to extend and reﬁne the analysis of the laboratory observations. The experimental model (5 m >< 5 m) represents a square urban district with a total of l4 streets of different Widths and 49 intersections (crossroads). The inﬂow discharge can be controlled in each street individually and the outﬂow discharges were measured downstream of each street. The numerical model Wolf was developed at the University of Liege and has been extensively used in ﬂood risk research (Beckers et al, 2013, Bruwier et al. 2015, Detrembleur et al. 2015). Several lessons could be learned from this combined experimental and numerical analysis. First, we found that the discharge partition in—between the streets is primarily controlled by the street widths. Second, although the standard shallow-water equations reproduce satisfactorily tnost of the ﬂow characteristics, adding a turbulence model improves the prediction of the shape and length of the ﬂow recirculations in the streets. Yet, this has little inﬂuence on the discharge partition because the computed recirculation widths are hardly affected by the turbulence model. The experiments and the numerical model also show that the water depths in the streets remain fairly constant in~between two intersections, while they drop suddenly downstream of each intersection as a result of complex ﬂow interactions at the intersections. This hints that friction has little inﬂuence on the water depths obtained in the experiments. However, tailored numerical tests demonstrate that this is a direct consequence of the distorted nature of the experimental setup. Indeed, the ratio between the water depth and the street width is close to 1 in the experiments, while it would be at least one order of magnitude lower in real-world conditions, even for extreme ﬂoods. Finally, remote sensing data, such as digital elevation models, are generally available on a regular grid, which makes it convenient to use also a Cartesian grid for hydraulic modelling, We show here that the discretization of the geometry of the buildings on such a Cartesian grid has a major inﬂuence on the modelling accuracy (overestimation of the overall ﬂow resistance). An extended shallow-water model based on non-isotropic porosity parameters is shown to improve substantially the prediction of the discharge partition in-between the streets. It is therefore considered as a valuable tool to advance urban ﬂood modelling in practice. From the lessons learned here, we recommend that future research focuses on the design and exploitation of a less distorted experimental model, as well as on the analysis of extra ﬂow processes such as transient conditions and interactions between overland ﬂow and pressurized ﬂow in underground passages. [less ▲]Detailed reference viewed: 18 (5 ULg) A laser proﬁlometry technique for monitoring ﬂuvial dike breaching in laboratory experimentsDewals, Benjamin ; Rifai, Ismail; Erpicum, Sébastien et alConference (2017, April)A challenging aspect for experimental modelling of ﬂuvial dike breaching is the continuous monitoring of the transient breach geometry. In dam breaching cases induced by ﬂow overtopping over the whole ... [more ▼]A challenging aspect for experimental modelling of ﬂuvial dike breaching is the continuous monitoring of the transient breach geometry. In dam breaching cases induced by ﬂow overtopping over the whole breach crest (plane erosion), a side view through a glass wall is sufﬁcient to monitor the breach formation. This approach can be ex- tended for 3D dam breach tests (spatial erosion) ifthe glass wall is located along the breach centreline. In contrast using a side view does not apply for monitoring ﬂuvial dike breaching, because the breach is not symmetric in this case. We present a non-intrusive, high resolution technique to record the breach development in experimental models of ﬂuvial dikes by means of a laser proﬁlometry (Rifai et al. 2016). Most methods used for monitoring dam and dike breaching involve the projection of a pattern (fringes, grid) on the dam or dike body and the analysis of its deformation on images recorded during the breaching (e.g., Pickett et al. 201 1, Frank and Hager 2014). A major limitation of these methods stems from reﬂection on the water surface, particularly in the vicinity of the breach where the free surface is irregular and rippled. This issue was addressed by Spinewine et al. (2004), who used a single laser sheet so that reﬂections on the water surface were strongly limited and did not hamper the accurate processing of each image. We have developed a similar laser proﬁlometry technique tailored for laboratory experiments on ﬂuvial dike breaching. The setup is simple and relatively low cost. It consists of a digital video camera (resolution of 1920 >< 1080 pixels at 60 frames per second) and a swiping red diode 30 mW laser that enables the projection of a laser sheet over the dike body. The 2D image coordinates of each defomied laser proﬁle incident on the dike are transformed into 3D object coordinates using the Direct Linear Transformation (DLT) algorithm. All 3D object coordinates computed over a swiping cycle of the laser are merged to generate a cloud of points. The DLT-based image processing method uses control points and reference axes, so that no prior knowledge is needed on the position, orientation and intrinsic characteristics of the camera, nor on the laser position. Refraction of the light and laser rays across the water surface needs to be taken into account, because the dike is partially submerged during the experiments. An ad hoc correction is therefore applied using the Snell-Descartes law. For dtis purpose, planar approximations are used to describe the shape of the water surface. In the presen- tation, we will discuss the resulting uncertainty and will detail the validation of the developed method based on conﬁgurations of known geometry with various complexity. The presented laser proﬁlometry technique allows for a rapid non-intrusive measurement of the dike geometry evolution. It is readily available for laboratory experiments and has proven its performance (Rifai et al. 2017). Further adjustments are needed for its application to cohesive dike material due to the reduced visibility resulting from the higher turbidity of water. [less ▲]Detailed reference viewed: 15 (1 ULg)