Last 7 days
Bookmark and Share    
See detailDesign of reprocessable poly(ɛ-caprolactone)-based shape-memory materials
Defize, Thomas ULg

Doctoral thesis (2017)

Shape-memory polymers (SMPs) are remarkable materials able to switch from a temporary shape to their initial permanent shape by crossing a thermal transition, e.g. glass or melting transition. Efficient ... [more ▼]

Shape-memory polymers (SMPs) are remarkable materials able to switch from a temporary shape to their initial permanent shape by crossing a thermal transition, e.g. glass or melting transition. Efficient shape-memory effect is notably observed for chemically cross- linked semi-crystalline polymers. Chemical networks of semi-crystalline poly(ε-caprolactone) (PCL) are widely studied for the development of SMPs especially when biomedical applications are foreseen. As these SMPs are irreversibly cross-linked material, their (re)processing is quite limited since they cannot be molten or solubilized after cross-linking. This prevents any recycling. Thereby, using reversible cross-linking reactions allowing the formation or cleavage of the network upon a selected stimulus raise tremendous interest for the development of smart SMPs. Chemically cross-linked but remarkably (re)processable shape-memory polymers (SMP) were designed by crosslinking poly(ε-caprolactone) (PCL) stars via reversible cycloaddition reactions. The thermo-reversible Diels-Alder (DA) reaction between furan and maleimide was investigated to crosslink the PCL matrix. However, the relatively low retro DA temperature of the furan-maleimide adducts led to some inelastic deformation during shape memory tensile cycles. In order to get rid of this drawback, two alternative approaches were investigated, i.e. the substitution of the DA reaction firstly by the efficient triazolinedione click chemistry, especially the very fast and reversible Alder-ene reaction of 1,2,4-triazoline-3,5- dione (TAD) with indole compounds and secondly by a photo-reversible reaction, typically the photo-induced (2+2) cycloaddition of coumarins. With these networks, the typical shape memory properties of PCL networks (high fixity and recovery ratios) were preserved while upon an external (light or stress) stimulus, the PCL network can be (re)processed efficiently. [less ▲]

Detailed reference viewed: 29 (3 ULg)
Full Text
Peer Reviewed
See detailThe prevention of fragility fractures in patients with non-metastatic prostate cancer: a position statement by the international osteoporosis foundation.
CIANFEROTTI, L; BERTOLDO, F; CARINI, M et al

in Oncotarget (2017)

Androgen deprivation therapy is commonly employed for the treatment of nonmetastatic prostate cancer as primary or adjuvant treatment. The skeleton is greatly compromised in men with prostate cancer ... [more ▼]

Androgen deprivation therapy is commonly employed for the treatment of nonmetastatic prostate cancer as primary or adjuvant treatment. The skeleton is greatly compromised in men with prostate cancer during androgen deprivation therapy because of the lack of androgens and estrogens, which are trophic factors for bone. Men receiving androgen deprivation therapy sustain variable degrees of bone loss with an increased risk of fragility fractures. Several bone antiresorptive agents have been tested in randomized controlled trials in these patients. Oral bisphosphonates, such as alendronate and risedronate, and intravenous bisphosphonates, such as pamidronate and zoledronic acid, have been shown to increase bone density and decrease the risk of fractures in men receiving androgen deprivation therapy. Denosumab, a fully monoclonal antibody that inhibits osteoclastic-mediated bone resorption, is also effective in increasing bone mineral density and reducing fracture rates in these patients. The assessment of fracture risk, T-score and/or the evaluation of prévalent fragility fractures are mandatory for the selection of patients who will benefit from antiresorptive therapy. In the future, new agents modulating bone turnover and skeletal muscle metabolism will be available for testing in these subjects. [less ▲]

Detailed reference viewed: 23 (3 ULg)
Full Text
See detailLa critique dans les revues d’architecture à Liège dans le contexte de l’activité éditoriale belge de l’Entre-deux-guerres.
Charlier, Sébastien ULg

Scientific conference (2017, May 18)

Loin de présenter un visage uniforme, la critique s’exprimant dans les revues d’architecture de l’entre-deux-guerres répond à des enjeux multiples et repose sur diverses postures qui peuvent être ... [more ▼]

Loin de présenter un visage uniforme, la critique s’exprimant dans les revues d’architecture de l’entre-deux-guerres répond à des enjeux multiples et repose sur diverses postures qui peuvent être publicitaires, doctrinaires ou corporatistes. Sur base de cette classification, cette communication propose d’analyser La Technique des travaux (1925-1940), L’Équerre (1928-1939) et Le Rez-de-chaussée (1928), trois revues dont la naissance est située à Liège, ville belge de seconde importance. En les caractérisant à la lumière d’organes similaires à portée nationale, elle entend montrer la diversité des profils de ceux qui se sont engagés dans la critique architecturale. Car tous les critiques ne sont pas architectes, loin de là. [less ▲]

Detailed reference viewed: 27 (0 ULg)
See detailQualité en chirurgie orthopédique
KURTH, William ULg

Scientific conference (2017, May 18)

Detailed reference viewed: 27 (0 ULg)
Full Text
Peer Reviewed
See detailImplementation of SFC for the quality control of pharmaceuticals
Dispas, Amandine ULg; Andri, Bertyl ULg; Lebrun, Pierre ULg et al

Conference (2017, May 17)

Detailed reference viewed: 12 (1 ULg)
Full Text
See detailRencontre avec Pascal Matthey
Crucifix, Benoît ULg

Speech/Talk (2017)

Detailed reference viewed: 23 (1 ULg)
Full Text
See detailCybercriminaliteit: materieel- en procedureelrechtelijke aspecten
Franssen, Vanessa ULg

Conference given outside the academic context (2017)

Detailed reference viewed: 23 (0 ULg)
Peer Reviewed
See detailL'interpellation stigmatisante comme élément de construction identitaire: le cas "Django Unchained"
Wintgens, Caroline ULg

Conference (2017, May 17)

La polémique apparue autour du film Django Unchained de Quentin Tarantino (2012) permet d’approcher la question de la représentation du stigmate. Mon étude portant sur cette polémique et sur les arguments ... [more ▼]

La polémique apparue autour du film Django Unchained de Quentin Tarantino (2012) permet d’approcher la question de la représentation du stigmate. Mon étude portant sur cette polémique et sur les arguments y étant mobilisés a montré que c’est la représentation d’éléments issus de la culture afro-américaine, ayant participé à la construction d’une identité pour les individus porteurs d’un stigmate ethnique, qui est particulièrement mise en cause. La polémique devient dès lors le lieu d’une resignification des attributs liés au stigmate et d’une réaffirmation de la culture de résistance élaborée autour de celui-ci par ceux qui en sont porteurs. Le terme Nigger et sa présence excessive dans le film ont notamment été relevés par de nombreux internautes. C’est dans ce cadre que nous approcherons la question toujours centrale de l’interpellation stigmatisante, en tant qu’elle semble à la fois devenir le lieu d’une réaffirmation identitaire et permettre l’émergence d’une « réponse habilitante » (Butler, 2008). [less ▲]

Detailed reference viewed: 14 (1 ULg)
Full Text
See detailA Journey Through Julia: A dynamic and fast language
Cuvelier, Thibaut ULg

Speech/Talk (2017)

Usually, dynamic programming languages (like Python, R, or MATLAB) are quite slow when executed, which causes performance problems in many applications. Julia is a blossoming language, both dynamic and ... [more ▼]

Usually, dynamic programming languages (like Python, R, or MATLAB) are quite slow when executed, which causes performance problems in many applications. Julia is a blossoming language, both dynamic and fast, fully open source, with a syntax that is very similar to that of MATLAB. This talk presents briefly Julia and its ecosystem. [less ▲]

Detailed reference viewed: 14 (2 ULg)
Full Text
See detailModulation of NMDA receptor mediated excitatory synaptic currents in dopamine neurons of the substantia nigra
Destreel, Geoffrey ULg; Seutin, Vincent ULg; Engel, Dominique ULg

Poster (2017, May 17)

Dopamine (DA) neurons of the substantia nigra pars compacta (SNc) exhibit two main firing modes, spontaneous single action potential (AP) firing and bursting. The amount of DA released by these neurons in ... [more ▼]

Dopamine (DA) neurons of the substantia nigra pars compacta (SNc) exhibit two main firing modes, spontaneous single action potential (AP) firing and bursting. The amount of DA released by these neurons in target areas depends on the presynaptic AP firing pattern and is essential to modulate several aspects of behavior such as the control of movement. Bursting activity is mediated by excitatory afferents and specifically by the activation of NMDA receptors (NMDARs). However, the level of activation of NMDARs at these synapses during spontaneous synaptic activity is unknown. We assessed the occupancy of the glycine binding sites of the NMDAR by testing the effects of coagonists and by blocking the uptake of glycine on spontaneous excitatory postsynaptic currents (sEPSCs) in DA neurons of the SNc. Parasagittal midbrain slices (300 – 350 µm thickness) were cut from the brains 16- to 26- days old Wistar rats using a vibratome. Whole-cell recordings were made using warm (~35C°) standard artificial cerebrospinal fluid. sEPSCs were pharmacologically isolated and recorded at +40 and -70 mV. A large NMDAR-sEPSC component was present at +40 mV as revealed by the application of 50 µM D-AP5 (n=8, P < 0.001). At -70 mV, D-AP5 had no effect on the EPSC, as expected (n=7, P = 0.52). The mean amplitude of the average NMDAR sEPSC measured at +40 mV increased significantly from 8.6 ± 0.8 pA in control conditions to 10.9 ± 1.0 pA during bath application of 300 μM glycine (n=10, P < 0.001). We also investigated the effect of D-serine, the other coagonist at the NMDAR glycine site. The mean NMDAR EPSC amplitude measured at +40 mV showed a tendency toward larger values, from 6.8 ± 0.8 pA in control conditions to 8.8 ± 1.1 pA in the presence of 100 µM D-serine (n=4). Blockade of the glycine transporter-1 (GlyT1) significantly increased the mean amplitude of NMDAR sEPSCs measured at +40 mV from 7.1 ± 0.5 pA in control conditions to 10.5 ± 0.8 pA in the presence of 5 μM NFPS (n=8, P < 0.001). At -70 mV, NFPS had no effect on the AMPAR-sEPSC component, as expected (n=8, P = 0.23). In conclusion, our results indicate that the NMDAR glycine sites are not saturated by glycine and D-serine during sEPSCs in control conditions. [less ▲]

Detailed reference viewed: 31 (18 ULg)
Full Text
See detailAharonov-Bohm oscillations of bosonic matter-wave beams in the presence of disorder and interaction
Chrétien, Renaud ULg; Dujardin, Julien; Petitjean, Cyril ULg et al

Poster (2017, May 17)

We study the one-dimensional (1D) transport properties of an ultracold gas of Bose-Einstein condensed atoms through Aharonov-Bohm (AB) rings. Our system consists of a Bose-Einstein condensate (BEC) that ... [more ▼]

We study the one-dimensional (1D) transport properties of an ultracold gas of Bose-Einstein condensed atoms through Aharonov-Bohm (AB) rings. Our system consists of a Bose-Einstein condensate (BEC) that is outcoupled from a magnetic trap into a 1D waveguide which is made of two semi-infinite leads that join a ring geometry exposed to a synthetic magnetic flux φ. We specifically investigate the effects both of a disorder potential and of a small atom-atom contact interaction strength on the AB oscillations. The main numerical tools that we use for this purpose are a mean-field Gross-Pitaevskii (GP) description and the truncated Wigner (tW) method. We find that a correlated disorder suppress the AB oscillations leaving thereby place to weaker amplitude, half period oscillations on transmission, namely the Aronov-Al’tshuler-Spivak (AAS) oscillations. The competition between disorder and interaction leads to a flip of the transmission at the AB flux φ = π. This flip could be a possible preliminary signature of an inversion of the coherent backscattering (CBS) peak. Our study paves the way to an analytical description of the inversion of that peak. [less ▲]

Detailed reference viewed: 16 (1 ULg)
Peer Reviewed
See detailNON-INVASIVE ANALYSIS OF POTENTIALLY DYSREGULATED MIRNAS IN ENDOMETRIOSIS
Munaut, Carine ULg; Emonard, Violaine; TIMMERMANS, Marie ULg et al

Conference (2017, May 17)

Detailed reference viewed: 22 (4 ULg)
Full Text
See detailOrganiser et animer des séances de cas pratiques en droit
Biquet, Christine ULg

Learning material (2017)

Detailed reference viewed: 14 (1 ULg)
Full Text
Peer Reviewed
See detailDefining thermal comfort boundaries for heating and cooling demand estimation in Iran's urban settlements
Roshan, GhR.; Farrokhzad, M.; Attia, Shady ULg

in Building & Environment (2017), 121

Iran has diverse climate variability, comfort boundaries for each geographic region must be defined in order to present current architectural design recommendations and proper mechanical systems design to ... [more ▼]

Iran has diverse climate variability, comfort boundaries for each geographic region must be defined in order to present current architectural design recommendations and proper mechanical systems design to meet building's heating and cooling energy demand. Therefore, two components of the temperature and relative humidity of 148 stations with the longest common statistical period of twenty years (1994–2014), which have been in daily scale were selected to calibrate and redefine the thermal boundary conditions in Iran. Givoni chart was used to define and visualize the bioclimatic conditions in buildings. The results of this study indicate that only 18% of the 148 stations days, falls in the thermal comfort bioclimatic conditions. After calibration of the base comfort temperature, we found that the upper threshold of this component varies from at least 22.62 °C for Ardebil to 25.94 °C for Dorudzan station and the low threshold of this component belongs to Ardebil with at least 20.13 °C up to its maximum value with 22 °C which belongs to Dorudzan. Spatial distribution of cooling and heating days show that their maximum threshold has been for cores in Northeastern half of Iran, Iran's Western half and some Central parts of Iran and the minimum threshold of these two components belongs to the beaches of north and south of the country. The findings present updated thermal comfort boundaries that can be used by architects, engineers and policy makers to achieve, in turn, more energy efficient homes and high quality indoor and outdoor living environments. [less ▲]

Detailed reference viewed: 50 (6 ULg)
Full Text
Peer Reviewed
See detailFirst Characterisation of Volatile Organic Compounds Emitted by Banana Plants
Berhal, Chadi ULg; De Clerck, Caroline ULg; Fauconnier, Marie-Laure ULg et al

in Scientific Reports (2017)

Banana (Musa sp.) ranks fourth in term of worldwide fruit production, and has economical and nutritional key values. The Cavendish cultivars correspond to more than 90% of the production of dessert banana ... [more ▼]

Banana (Musa sp.) ranks fourth in term of worldwide fruit production, and has economical and nutritional key values. The Cavendish cultivars correspond to more than 90% of the production of dessert banana while cooking cultivars are widely consumed locally around the banana belt production area. Many plants, if not all, produce Volatile Organic Compounds (VOCs) as a means of communication with their environment. Although flower and fruit VOCs have been studied for banana, the VOCs produced by the plant have never been identified despite their importance in plant health and development. A volatile collection methodology was optimized to improve the sensitivity and reproducibility of VOCs analysis from banana plants. We have identified 11 VOCs for the Cavendish, mainly (E,E)-α-farnesene (87.90 ± 11.28 ng/μl), methyl salicylate (33.82 ± 14.29) and 6-methyl-5-hepten-2-one (29.60 ± 11.66), and 14 VOCs for the Pacific Plantain cultivar, mainly (Z,E)-α-farnesene (799.64 ± 503.15), (E,E)-α-farnesene (571.24 ± 381.70) and (E) β ocimene (241.76 ± 158.49). This exploratory study paves the way for an in-depth characterisation of VOCs emitted by Musa plants. [less ▲]

Detailed reference viewed: 51 (4 ULg)
Full Text
See detailFish introductions, newt decline and paedomorph extinction
Denoël, Mathieu ULg

Scientific conference (2017, May 16)

Detailed reference viewed: 21 (4 ULg)