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See detailMagnetosphere-ionosphere mapping at Jupiter: Quantifying the effects of using different internal field models
Vogt, Marissa; Bunce, Emma; Kivelson, Margaret et al

in Journal of Geophysical Research. Space Physics (2015), 120

The lack of global field models accurate beyond the inner magnetosphere (<30 RJ) makes it difficult to relate Jupiter's polar auroral features to magnetospheric source regions. We recently developed a ... [more ▼]

The lack of global field models accurate beyond the inner magnetosphere (<30 RJ) makes it difficult to relate Jupiter's polar auroral features to magnetospheric source regions. We recently developed a model that maps Jupiter's equatorial magnetosphere to the ionosphere using a flux equivalence calculation that requires equal flux at the equatorial and ionospheric ends of flux tubes. This approach is more accurate than tracing field lines in a global field model but only if it is based on an accurate model of Jupiter's internal field. At present there are three widely used internal field models—Voyager Io Pioneer 4 (VIP4), the Grodent Anomaly Model (GAM), and VIP Anomaly Longitude (VIPAL). The purpose of this study is to quantify how the choice of an internal field model affects the mapping of various auroral features using the flux equivalence calculation. We find that different internal field models can shift the ionospheric mapping of points in the equatorial plane by several degrees and shift the magnetospheric mapping to the equator by ~30 RJ radially and by less than 1 h in local time. These shifts are consistent with differences in how well each model maps the Ganymede footprint, underscoring the need for more accurate Jovian internal field models. We discuss differences in the mapping of specific auroral features and the size and location of the open/closed field line boundary. Understanding these differences is important for the continued analysis of Hubble Space Telescope images and in planning for Juno's arrival at Jupiter in 2016. [less ▲]

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See detailGian Matteo Giberti et les lettres à travers la correspondance de jeunesse
Valenti, Gianluca ULg

Conference (2015, February 27)

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See detailWho’s the gatekeeper? Ensuring and Legitimating a Participatory Decision-Making Process in the context of Nuclear Waste Management
Parotte, Céline ULg

Conference (2015, February 27)

In Belgium, Nuclear Waste Management (NWM) is conducted by a Federal Agency called ONDRAF - i.e. the “National Agency for Radioactive Waste and Enriched Fissile Materials”. Adhering to a largely accepted ... [more ▼]

In Belgium, Nuclear Waste Management (NWM) is conducted by a Federal Agency called ONDRAF - i.e. the “National Agency for Radioactive Waste and Enriched Fissile Materials”. Adhering to a largely accepted vision, NWM is considered by ONDRAF as a long-term and complex issue, consisting in technical, social, economic and ethical questions. In this respect, scientific literature invites to clarify and address those aspects in a decision-making process that could benefit from meaningful public participation (Callon, Lascoumes, and Barthes 2001). In this context, many stakeholders (e.g. citizens, researchers, industrialists, civil society organizations, the European Union... and ONDRAF itself) are in demand of a “conductor” that can organize, ensure and legitimize such a participatory decision-making process. Many questions emerge from this demand. Who can be the gatekeeper of this process? What could be his role? For which purposes? In addition to that, how should participation be organized/assessed/controlled? To that regard, the purpose of this paper is twofold. First, I elaborate a possible definition of “gatekeeping a participatory decision-making process concerning NWM in Belgium”. Second, I question the possible role of Technology Assessment (TA) - as an institution as well as a set of approached - in this context. To address those questions, I rely on a combination of theoretical and empirical materials – i.e. semi directive interviews with policy makers and members of Belgian and French agencies in charge of NWM. [less ▲]

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See detail"Mimer le savoir pour mieux le miner : le guide pratique selon Pierre La Police"
Belloi, Livio ULg

Conference (2015, February 27)

En s'appuyant sur "Nos meilleurs amis et l'acte interdit" (Cornelius, 2011, 4e édition), la présente communication examine le traitement parodique que le dessinateur français Pierre La Police réserve au ... [more ▼]

En s'appuyant sur "Nos meilleurs amis et l'acte interdit" (Cornelius, 2011, 4e édition), la présente communication examine le traitement parodique que le dessinateur français Pierre La Police réserve au discours à caractère encyclopédique ou didactique. Dans son rapport distancié et facétieux au savoir, Pierre La Police creuse le sillon ouvert par Gustave Flaubert et son fameux "Dictionnaire des idées reçues". [less ▲]

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See detailTensor Representation of Spin States
Giraud, Olivier; Braun, Daniel; Baguette, Dorian ULg et al

in Physical Review Letters (2015), 114

We propose a generalization of the Bloch sphere representation for arbitrary spin states. It provides a compact and elegant representation of spin density matrices in terms of tensors that share the most ... [more ▼]

We propose a generalization of the Bloch sphere representation for arbitrary spin states. It provides a compact and elegant representation of spin density matrices in terms of tensors that share the most important properties of Bloch vectors. Our representation, based on covariant matrices introduced by Weinberg in the context of quantum field theory, allows for a simple parametrization of coherent spin states, and a straightforward transformation of density matrices under local unitary and partial tracing operations. It enables us to provide a criterion for anticoherence, relevant in a broader context such as quantum polarization of light. [less ▲]

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See detail3D human motion analysis based on ultra-low resolution sensors
Pierard, Sébastien ULg

Scientific conference (2015, February 27)

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See detailComparison of early stages of colorectal cancer by label free proteomics
QUESADA CALVO, Florence ULg; MEUWIS, Marie-Alice ULg; Bertrand, Virginie ULg et al

in Acta Gastroenterologica (2015, February 27)

Introduction and objectives: Colorectal cancer (CRC) is the second most frequent cancer in women and the third in men. Identification of the mechanisms of progression in these early CRC stages is ... [more ▼]

Introduction and objectives: Colorectal cancer (CRC) is the second most frequent cancer in women and the third in men. Identification of the mechanisms of progression in these early CRC stages is important to develop new diagnostic and therapeutic tools. Formalin-Fixed Paraffin-Embedded (FFPE) specimens are materials that enable proteomic clinical research. Hence our aim was to address the comparison of FFPE samples from early CRC stages patients using shotgun proteomic analysis. Methods: We performed a retrospective study on 36 CRC tissue samples (pT1N0M0, n=16 and pT2N0M0, n=20) compared together and with 40 control tissue samples (20 patients with diverticulitis, using paired inflamed (DI) and healthy tissue (DH)). Each tissue slice was macrodissected to enrich in epithelial cells. We used FFPE-FASP kit (Expedeon) for sample preparation and protein digests were analyzed using 2D-nanoAquity UPLC separation online with Q-Tof Synapt HDMSTM G2 using ion mobility as additional separation. We performed protein identification and differential analysis using Progenesis QI for proteomics (Nonlinear Dynamics). Results and discussion: We selected 149 proteins differentially distributed between T1 and T2 CRC stages which were not significantly different between CRC and DH or DI. Only 30 proteins were significantly more abundant in T1 versus T2 and 119 were distributed inversely, with a minimum fold ratio of 2. Among those, ATP synthase subunit beta, Aspartate-tRNA ligase, Haptoglobin and Kininogen were identified. . Moreover, we validated Kininogen and 3 others proteins with a significant differential distribution between pT1N0M0 and pT2N0M0 stages by immunohistochemistry. Conclusion: This FFPE retrospective study comparing T1 and T2 CRC highlighted proteins already previously identified as potential CRC biomarkers. These proteins may reflect important early changes in cancer development and may help understanding early tumor progression. [less ▲]

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See detailPACITA "User" Summer Schools in Liège 2012 and Cork 2014
Rosskamp, Benedikt ULg; Fitzgerald, Ciara

Conference (2015, February 27)

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See detailPier Francesco Riccio e Pietro Aretino alla corte di Cosimo I de' Medici
Geremicca, Antonio ULg

Scientific conference (2015, February 26)

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See detailPratiques de détournement du jeu vidéo
Barnabé, Fanny ULg

Scientific conference (2015, February 26)

Séance de cours sur les différentes pratiques de détournement du jeu vidéo par les joueurs (fanfictions, machinimas, speedrun, modding,...).

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See detailEtude sur la sexualité en milieu carcéral belge: De l'enfermement de la sexualité à la liberté d'adaptation des comportements sexuels.
Francois, Axelle ULg

Doctoral thesis (2015)

En Belgique, la question de la sexualité des personnes incarcérées a rarement fait l’objet de recherches de la part des chercheurs en sciences humaines, particulièrement des criminologues. A partir ... [more ▼]

En Belgique, la question de la sexualité des personnes incarcérées a rarement fait l’objet de recherches de la part des chercheurs en sciences humaines, particulièrement des criminologues. A partir d’informations obtenues auprès de 530 hommes incarcérés au sein de dix établissements pénitentiaires belges francophones, nous avons réalisé une étude de la sexualité en milieu carcéral perçue et vécue par les personnes détenues. S’appuyant ainsi sur le modèle de la privation tel que développé par Sykes (1958), notre recherche se fonde sur l’hypothèse principale suivante : « la privation de relations hétérosexuelles en prison engendre chez le détenu un sentiment de frustration et en réponse à ce sentiment, l’individu incarcéré cherche à s’adapter. Cette adaptation suit différentes trajectoires allant de pratiques sexuelles plus solitaires à des pratiques sexuelles de substitution impliquant un rapport à l’autre. Elle porte également sur les discours et les comportements des personnes dans un contexte carcéral particulier et est influencée non seulement par leurs perceptions mais aussi par leur vécu ». Considérant cette hypothèse générale, notre étude entendait ainsi dresser un portrait actualisé de la sexualité incarcérée qui dépasse les apparences et les discours officiels. Grâce à la mise en œuvre d’une méthodologie d’analyse quantitative, six objectifs plus spécifiques ont été investigués. Pour étudier les représentations et le vécu de la sexualité en milieu carcéral de notre échantillon, nous nous sommes d’abord appuyée sur les apports théoriques et scientifiques de la littérature spécifique. Ensuite, au moyen de traitements statistiques appliqués à notre base de données, nous avons cherché pour chaque axe des corrélations entre d’une part, les variables relatives aux représentations et vécus sexuels des détenus et d’autre part, des variables caractéristiques comme par exemple l’âge, la durée d’incarcération, l’existence d’un partenaire affectif extérieur, le bénéfice de visites en prison et la participation aux activités en détention,…. [less ▲]

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See detailLes peptides natriurétiques: le point de vue du biologiste
LE GOFF, Caroline ULg

Conference (2015, February 26)

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See detailLes peptides natriurétiques: le point de vue du biologiste
LE GOFF, Caroline ULg

Conference (2015, February 26)

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See detailPotential Proteomic Biomarkers Associated with Mucosal Healing and Relapse Prediction after IFX Withdrawals in Crohn’s Disease
MEUWIS, Marie-Alice ULg; QUESADA CALVO, Florence ULg; Baiwir, Dominique ULg et al

in Acta gastroenterologica (2015, February 26)

Introduction and objectives: In Crohn's disease (CD), there is a discrepancy between clinical activity of the disease (symptoms) and intestinal healing. However absence of tissue healing is associated ... [more ▼]

Introduction and objectives: In Crohn's disease (CD), there is a discrepancy between clinical activity of the disease (symptoms) and intestinal healing. However absence of tissue healing is associated with the risk of relapse and tissue damage progression. Endoscopy is costly and invasive. Hence biomarkers correlating with intestinal healing could improve disease management and potentially decrease the number of endoscopy when patients are in clinical remission. Aim: We aimed to identify potential biomarkers associated to CD mucosal healing and relapse after IFX withdrawals by a shotgun label-free proteomic study. Methods: We used the STORI1 clinical trial cohort (n=103) aiming at identifying markers associated to relapse prediction after Infliximab treatment withdrawals. We used serum samples of patients in clinical remission (at base line). We grouped these according to the degree of intestinal healing seen at endoscopy or according to relapse occurrence during the 28 month follow-up and composed pooled samples. We performed depletion of the 20 most abundant plasma proteins on each serum pools and ran a proteomic label-free differential analysis using 2D-nanoUPLC-MSE HDMS Synapt G2 for data acquisition. We performed different statistical analysis. Moreover, a Gene Ontology annotation was also performed for the potential biomarkers highlighted. Results and Discussion: We identified analysing these depleted serum pools 430 different proteins and 188 proteins common to all samples. Among these, 40 were found with a significant differential abundance in the groups compared. We selected some among the most significant one (ratio>1.3) or being by nature consistent with the context of this study (sample origin and clinical question addressed). For example, the C-reactive protein (CRP) was found with a significant Ratio of 2 between Relapsers and Non Relapsers. The other potential biomarkers associated to mucosal healing or to relapse prediction, were selected for further validation by Western Blot analysis (WB), routine laboratory tests and also by a Mass Spectrometry based technology: multiplexed selected reaction monitoring (SRM). Multiplexed SRM will enable quantitative analysis of these candidates in each individual patient as well as WB tests. Conclusions: This research strategy and the validation results on potential biomarkers associated to mucosal healing or relapse after treatment cessation in this cohort of CD patients, as well as tests done on other CD patients, might provide new opportunities for patient follow-up test developments. The next step is to perform SRM validation on the STORI cohort and design signatures using these potential biomarkers SRM data for prognosis power evaluation. 1. Louis E, Mary JY, Vernier-Massouille G, et al. Maintenance of remission among patients with Crohn's disease on antimetabolite therapy after infliximab therapy is stopped. Gastroenterology 2012;142:63-70 e5; quiz e31. [less ▲]

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See detailTeaching and Training TA
Delvenne, Pierre ULg; Rosskamp, Benedikt ULg; Bütschi, Danielle et al

Poster (2015, February 26)

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See detailTechnology Assessment in East Asia: Experiences and New Approaches
Moniz, Antonio; Yoshizawa, Go; Van Oudheusden, Michiel ULg

Conference (2015, February 25)

Integrating social and ethical concerns in innovation practice is a well-documented and debated issue in the United States and in Europe (namely through the EU-wide PACITA project). Related developments ... [more ▼]

Integrating social and ethical concerns in innovation practice is a well-documented and debated issue in the United States and in Europe (namely through the EU-wide PACITA project). Related developments in other parts of the world are less discernible – at least to Westerns. Yet, as witnessed by the emergence of technology assessment (TA) in countries like Japan, TA and TA-like activities have a unique and long history and continue to play a role in contemporary STI processes (e.g. in the area of citizen engagement with nanotechnologies, or energy policy). Taking these observations as its entry point, this panel asks how STI governance is locally enacted in Asian knowledge-driven economies. Like their Western counterparts, nations like China, Indonesia, Japan, the Republic of Korea, Singapore, Taiwan, etc., have undergone, and continue to undergo, rapid science- and technology-driven industrialization. In these processes, TA and TA-like activities develop with STI policies and programs and typically do so in nation- and region-specific ways. To render these processes, policies, and programs visible, and understand their implications for STI governance, this panel will discuss contributions that: • Describe and conceptualize how TA and TA-like activities have emerged in Asian KBEs, and in what particular forms (e.g. academic and parliamentary TA programs, linked to certain technologies and/or actors, which methods are used and why, etc.). • Reflect how these activities has evolved with, sustained, and/or countered, STI policies on the regional, national, and international level. • Compare and contrast how TA is, or is not, institutionalized in Asian countries and regions, e.g. through initiatives to initiate or abolish various TA forms, such as health TA, early-warning TA, and parliamentary TA; and/or point to prospects for TA capacity building. • Situate the above processes within a broader theory of, and movement towards, new STI governance frameworks, such as anticipatory governance, responsible innovation, public engagement, and/or others. By placing the development in historical, sociological, and comparative perspective, the panel seeks to open a space for critical reflection on the potential, problems, and limitations of initiating TA in Asia and draw connections to STI governance processes in other KBEs across the globe. [less ▲]

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See detailGranular transport in driven granular gas
Noirhomme, Martial ULg; Opsomer, Eric ULg; Ludewig, François ULg et al

in European Physical Journal E -- Soft Matter (2015), 38

We numerically and theoretically investigate the behavior of a granular gas driven by asymmetric plates. The injection of energy in the dissipative system differs from one side to the opposite one. We ... [more ▼]

We numerically and theoretically investigate the behavior of a granular gas driven by asymmetric plates. The injection of energy in the dissipative system differs from one side to the opposite one. We prove that the dynamical clustering which is expected for such a system is affected by the asymmetry. As a consequence, the cluster position can be fully controlled. This property could lead to various applications in the handling of granular materials in low-gravity environment. Moreover, the dynamical cluster is characterized by natural oscillations which are also captured by a model. These oscillations are mainly related to the cluster size, thus providing an original way to probe the clustering behavior. [less ▲]

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See detailLivre Blanc Céréales
Watillon, Bernard ULg; Bodson, Bernard ULg

Book published by Gembloux Agro-Bio Tech - Edition février 2015 (2015)

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