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See detailL'éveil de la matrix-gla-protéine sonnera le glas des calcifications vasculaires
DELANAYE, Pierre ULg; Liabeuf, Sophie; BOUQUEGNEAU, Antoine ULg et al

in Néphrologie & Thérapeutique (in press)

La matrix-gla-protéine (MGP) est principalement sécrétée par les chondrocytes et les cellules musculaires lisses des parois vasculaires. Son rôle est d’inhiber localement le développement des ... [more ▼]

La matrix-gla-protéine (MGP) est principalement sécrétée par les chondrocytes et les cellules musculaires lisses des parois vasculaires. Son rôle est d’inhiber localement le développement des calcifications vasculaires. MGP doit bénéficier de deux processus post-transcriptionnels avant d’être pleinement active : une phosphorylation de résidus sérine et une carboxylation de résidus glutamate. Cette carboxylation ne peut se faire qu’en présence de quantité suffisante de vitamine K. Plusieurs formes de MGP circulent donc dans le plasma, certaines étant totalement inactives (la MGP déphosphorylée et décarboxylée), d’autres possédant une activité biologique variable en fonction du nombre de sites carboxylés ou phosphorylés. Il existe un lien théorique étroit entre MGP, vitamine K, calcifications vasculaires et maladies cardiovasculaires et ce, particulièrement chez les patients souffrant d’insuffisance rénale chronique, a fortiori s’ils sont dialysés. Si l’existence de ce lien a été démontrée via de nombreuses et solides données fondamentales, les données cliniques restent, à ce jour, observationnelles et doivent donc être interprétées avec prudence. Mesurer une fraction de MGP dans le plasma pour estimer le degré de calcification d’un patient donné n’est pas encore d’actualité . La forme inactive pourrait être utile pour juger des réserves en vitamine K au niveau vasculaire. Dans cet article de revue, nous reviendrons sur les bases théoriques du rôle de MGP dans le processus de calcification vasculaire, sur le défi analytique que représente sa détermination dans le plasma, ainsi que sur les liens entre MGP, vitamine K et calcifications vasculaires en population géne´ rale et chez les patients insuffisants rénaux. [less ▲]

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See detailConcentration, Activity and Biochemical Characterization of Myeloperoxidase in Fresh and Post-thaw equine semen and their Implication on Freezability
Ponthier, Jérôme ULg; Franck, Thierry ULg; Parrilla Hernandez, Sonia ULg et al

in Reproduction in Domestic Animals (in press)

Myeloperoxidase (MPO) is a pro-oxidant enzyme associated with decreased motility in thawed equine semen. This study aimed to describe MPO concentration, activity and subunits in raw and thawed semen and ... [more ▼]

Myeloperoxidase (MPO) is a pro-oxidant enzyme associated with decreased motility in thawed equine semen. This study aimed to describe MPO concentration, activity and subunits in raw and thawed semen and to correlate these data with motilities in raw and thawed semen. Semen samples from five stallions were collected four times. Motilities were assessed in raw and thawed semen. MPO assays were performed in raw seminal plasma, raw sperm-rich pellet and thawed semen. Total and active MPO concentrations were, respectively, assayed by enzyme-linked immunosorbent assay and specific immunological extraction followed by enzymatic detection. MPO subunits present in semen were characterized by Western 3 blot. Purified active MPO was added in PBS and freezing extender to control its activity during freezing procedure. Differences between medians were determined using Kruskal– Wallis test, and correlations were determined using Spearman’s test for nonparametric data. Active MPO concentration was low in seminal plasma and thawed semen, but high in pellet (p = 0.0058), as the opposite relation was observed for total MPO concentration (p < 0.0001). In seminal plasma and post- thaw semen, inactive 86-kDa MPO precursor was mainly observed. Purified MPO activity was decreased in the extender (p = 0.0286). MPO activity in pellet was highly correlated with thawed progressive motility (r = 􏰑0.5576, p = 0.0086). Inac- tive MPO precursor and unknown low molecular weight inactive MPO precursor subunits explain low MPO activity in semen. Major MPO activity was observed in pellet, and post- thaw loss of activity is partially explained by MPO inactiva- tion in extender. Thawed semen motility was negatively correlated with MPO activity in pellet, becoming a potential freezability predictor. [less ▲]

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See detailLe développement de la compétence scripturale en FLS/FLE à l'université à l'aide des TIC : perceptions, pratiques et pistes d'exploitation
Dezutter, Olivier; Bleys, Françoise; Poirier, Vicky et al

in Les Centres de langues et la mise en œuvre des politiques linguistiques dans l’enseignement supérieur : Enseignement – Recherche - Mobilités (in press)

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See detailMinor compounds and oxidative stability of mono-varietal virgin olive oils produced in eastern of Morocco
Mansouri, Farid; Benmoumen, Abdessamad; Richard, Gaetan ULg et al

in Food Chemistry (in press)

The aim of this study is to characterize monovarietal virgin olive oils (VOOs) of new high-density plantings system of three cultivars (Arbequina, Arbosana and Koroneiki) which have been recently ... [more ▼]

The aim of this study is to characterize monovarietal virgin olive oils (VOOs) of new high-density plantings system of three cultivars (Arbequina, Arbosana and Koroneiki) which have been recently introduced in the eastern mediterranean region of Morocco. In this study, we have also conducted comparison between those monovarietal VOOs and olive oil of the local olive cultivar Picholine marocaine. Monovarietal VOOs characterization has been carried out by analysing several parameters, including quality index and olive oil stability to oxidation. Significant differences between the analysed olive oils were highlighted. They depend on cultivars and technological conditions of processing. We have noticed that Koroneiki olive oil have higher content of phenols (459.48 mg kg-1) and have the best value of oxidative stability (93.16 h). On the other hand Arbrosana’s VOO has low content of total phenols (260.85 mg kg-1) but it was distinguished by its higher content of alpha-tocopherol (460.07 mg kg-1). In addition, ten phenolic compounds present in virgin olive oils, were identified and quantitatively assessed by HPLC. Hydroxytyrosol, tyrosol, luteoline, pinoresinol and apigenin were the main phenolic compounds in those analyzed monovarietal VOOS. [less ▲]

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See detailTien Shan geohazards database: Earthquakes and landslides
Havenith, Hans-Balder ULg; Strom, Alexander; Torgoev, Isakbek et al

in Geomorphology (in press)

In this paper we present new and review already existing landslide and earthquake data for a large part of the Tien Shan, Central Asia. For the same area, only partial databases for sub-regions have been ... [more ▼]

In this paper we present new and review already existing landslide and earthquake data for a large part of the Tien Shan, Central Asia. For the same area, only partial databases for sub-regions have been presented previously. They were compiled and new data were added to fill the gaps between the databases. Major new inputs are products of the Central Asia Seismic Risk Initiative (CASRI): a tentative digital map of active faults (even with indication of characteristic or possible maximum magnitude) and the earthquake catalogue of Central Asia until 2009 that was now updated with USGS data (to May 2014). The new compiled landslide inventory contains existing records of 1600 previously mapped mass movements and more than 1800 new landslide data. Considering presently available seismo-tectonic and landslide data, a target region of 1200 km (E–W) by 600 km (N–S) was defined for the production of more or less continuous geohazards information. This target region includes the entire Kyrgyz Tien Shan, the South-Western Tien Shan in Tajikistan, the Fergana Basin (Kyrgyzstan, Tajikistan and Uzbekistan) as well as the Western part in Uzbekistan, the North-Easternmost part in Kazakhstan and a small part of the Eastern Chinese Tien Shan (for the zones outside Kyrgyzstan and Tajikistan, only limited information was available and compiled)... [less ▲]

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See detailLe français – sur objectifs universitaires – dans les politiques linguistiques et les centres de langues des universités marocaines : état d’une réflexion et esquisse d’un programme
Defays, Jean-Marc ULg; Jaafar, Khalid

in Defays, Jean-Marc (Ed.) Vingt ans de FLE. Faits et gestes de la didactique du français langue étrangère et seconde de 1995 à 2015 - Tome 2 : Contextualisations (in press)

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See detailComique et didactique : le rire en classe de langue ?
Defays, Jean-Marc ULg

in Vivre le Français : Revue de l'Association Belge des Professeurs de Français (in press), 245

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See detailRisques et périls d'opposer "Langue de culture" et "Langue de service"
Defays, Jean-Marc ULg

in Cahiers de l’ASDIFLE (in press), 27

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See detailMetabolic profile of mixed culture acidogenic fermentation of lignocellulosic residues and the effect of upstream substrate fractionation by steam explosion
Perimenis, Anastasios; van Aarle, Ingrid; Nicolay, Thomas et al

in Biomass Conversion and Biorefinery (in press)

Lignocellulosic biomass residues have attracted attention for the sustainable production of molecules for material and energetic use through biochemical conversion. Their recalcitrant structure prevents a ... [more ▼]

Lignocellulosic biomass residues have attracted attention for the sustainable production of molecules for material and energetic use through biochemical conversion. Their recalcitrant structure prevents a broader use and asks for the development of sustainable techniques that can efficiently separate, recover and valorize the constituting components. In a cascading concept, residual streams of such processes can be further exploited in an attempt to valorize the largest possible fraction of the initial material. Three lignocellulosic substrates, namely dried sugar beet pulp, wheat bran and miscanthus straw, were upstream fractionated by steam explosion to extract the hemicellulose fraction. This study evaluated the valorization of the residual solid fraction through mixed acidogenic fermentation for the production of volatile fatty acids (VFA) as platform chemicals. Batch experiments have been conducted for the reference material (non-treated) and the solid fraction remaining after steam explosion, with and without the addition of an external mixed inoculum. Steam explosion residues contained less hemicellulose than the initial materials. The difference in the fermentation profile between steam explosion residues and non-treated substrates is dependent on the substrate. Maximum total VFA (tVFA) concentration was 18.8 gCOD/kgmixed_liquor, and maximum yield of chemical oxygen demand (COD) conversion into tVFAwas 33 % for the case of non-treated inoculated beet pulp. [less ▲]

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See detailProcédures d'attribution
Durviaux, Ann-Lawrence ULg

in Durviaux, Ann-Lawrence (Ed.) La nouvelle directive "secteurs classiques" sur les marchés publics (in press)

Analyse de la directive 2014/24/UE

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See detailSalsa au LASLA : lemmatisation et exploitation statistique de la Passio sanctae Salsae
Philippart de Foy, Caroline ULg

in Autour de la Passion de sainte Salsa : Spécificité et originalité de l’hagiographie latine africaine (IVe-Ve siècles) (in press)

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See detailChapter 2: Islamic Food Practices in a Migration Context: an Ethnography among Moroccan Women in Milan (Italy)
Mescoli, Elsa ULg

in Toguslu, Erkan (Ed.) Everyday Life Practices of Muslims in Europe (in press)

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See detailStudio Alchimia
Prina, Daniela ULg

in Atkinson, Harriett; Edwards, Clive; Kettley, Sarah (Eds.) et al Encyclopedia of Design (in press)

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See detailZanuso, Marco
Prina, Daniela ULg

in Atkinson, Harriet; Edwards, Clive; Kettley, Sarah (Eds.) et al Encyclopedia of Design (in press)

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See detailKomödie, Rührstück, unheimliche Erzählung. Einquartierungen in der Literatur des 18. und frühen 19. Jahrhunderts
Viehöver, Vera ULg

in Genton, François; Nicklas, Thomas (Eds.) Soldats et civils. Échanges épistolaires et culturels au XVIIIe siècle (in press)

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See detailGismondi, Ernesto
Prina, Daniela ULg

in Atkinson, Harriet; Edwards, Clive; Kettley, Sarah (Eds.) et al Encyclopedia of Design (in press)

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See detailColombo, Joe Cesare
Prina, Daniela ULg

in Atkinson, Harriet; Edwards, Clive; Kettley, Sarah (Eds.) et al Encyclopedia of Design (in press)

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See detailBranzi, Andrea
Prina, Daniela ULg

in Atkinson, Harriet; Edwards, Clive; Kettley, Sarah (Eds.) et al Encyclopedia of Design (in press)

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See detailArchizoom
Prina, Daniela ULg

in Atkinson, Harriet; Edwards, Clive; Kettley, Sarah (Eds.) et al Encyclopedia of Design (in press)

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