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See detailMethodological approach for the implementation of a simulator in augmented reality in a radiation therapy department
Servotte, Jean-Christophe ULiege; Guillaume, Michèle ULiege; BOGA, Deniz ULiege et al

in International Journal of Healthcare Management (2017), 10(3), 154-159

Radiation therapy (RT) is one of the cornerstones for the treatment of cancer. In most countries RT machines are handled by professionals benefitting from an ad hoc training in theoretical knowledge as ... [more ▼]

Radiation therapy (RT) is one of the cornerstones for the treatment of cancer. In most countries RT machines are handled by professionals benefitting from an ad hoc training in theoretical knowledge as well as technical and non-technical skills. In Belgium, RT departments are hiring in nurses for this activity. In countries where there is a specified core curriculum for basic training of radiation technologist, this basic training falls short once in practice and there is an obvious requirement for a continuous updating of skills in order to keep up with the accelerating evolution of technology. Therefore, the decision has been taken to implement a simulator in augmented reality in the RT department in Liège, to face the double challenge i.e. basic professional training as well as continuous education in technical and nontechnical skills and Crew Resource Management. We describe a methodological approach to implement this simulator in augmented reality. [less ▲]

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See detailLe principe non bis in idem et les procédures mixtes : un camouflet infligé à la jurisprudence Zalotoukhine ?
Michiels, Olivier ULiege; Falque, Géraldine ULiege

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2017), (2017/23), 1069-1078

Pour lutter contre certains comportements socialement inacceptables, les États peuvent concevoir des réponses juridiques complémentaires au moyen de procédures mixtes pour autant que celles-ci forment un ... [more ▼]

Pour lutter contre certains comportements socialement inacceptables, les États peuvent concevoir des réponses juridiques complémentaires au moyen de procédures mixtes pour autant que celles-ci forment un tout cohérent, c’est-à-dire qu’elles soient liées par un lien matériel et temporel suffisamment étroit. Le cumul des sanctions pénales et administratives est autorisé dès lors que les deux procédures poursuivent des buts complémentaires et traitent d’aspects différents de l’acte préjudiciable, que le cumul des sanctions soit prévisible, qu’il n’y ait pas de répétition dans la collecte et dans l’appréciation des preuves et qu’un mécanisme de compensation entre les sanctions soit prévu. [less ▲]

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See detailCoherent backscattering of bosonic matter-wave in the presence of disorder and interaction
Chrétien, Renaud ULiege; Dujardin, Julien; Petitjean, Cyril ULiege et al

Poster (2017, June 09)

Coherent backscattering, which is an enhancement of the backscattered intensity of a light going through a medium made of point-like scatterers, is known as one of the most robust interference effects. It ... [more ▼]

Coherent backscattering, which is an enhancement of the backscattered intensity of a light going through a medium made of point-like scatterers, is known as one of the most robust interference effects. It has been shown, although it is nowadays not fully understood yet, that in the presence of non-linearities, this enhancement turns to an inhibition. We propose to study that effect by means of a system in which we study the transport of a Bose-Einstein condensate through Aharonov-Bohm rings in the presence of interaction and disorder. We find that our system is indeed a good candidate to observe the coherent peak’s inversion and is also suitable for more feasible theoretical calculations than in the original case. [less ▲]

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See detailVandalization of A.Kapoor's "Dirty corner"
Verbeeck, Muriel ULiege

Scientific conference (2017, June 09)

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See detailAccompagner et prendre soin des personnes âgées : sensibilisation à l’âgisme et à son impact en psychopathologie
Missotten, Pierre ULiege

Conference given outside the academic context (2017)

Detailed reference viewed: 20 (2 ULiège)
See detailLa caricature par la manière : la technique des images selon les Goncourt
Stienon, Valérie ULiege

Conference (2017, June 09)

Retraçant le parcours de Gavarni, évoquant leur amitié avec Rops, commentant les gravures destinées à illustrer leurs propres ouvrages, les Goncourt ne tiennent pas seulement un discours sur l’esthétique ... [more ▼]

Retraçant le parcours de Gavarni, évoquant leur amitié avec Rops, commentant les gravures destinées à illustrer leurs propres ouvrages, les Goncourt ne tiennent pas seulement un discours sur l’esthétique de l’image, ils disent aussi la médiation technique qui est à son origine. Gravure, lithographie, eau-forte ont leur place dans ce discours certes discret, mais précis et récurrent, qui conduit à s’interroger sur un savoir technique de la caricature propre aux Goncourt. La communication vise d’abord à mettre en évidence la nature et la portée de leurs propos sur les étapes matérielles intervenant dans la fabrique des images caricaturales, que ce savoir émane des sociabilités artistiques et culturelles (société des aquafortistes à laquelle est lié Rops, notamment) ou d’une expérience de participation à la presse. Il s’agit ensuite de déceler, dans l’essai, la fiction romanesque et le journal, les prises de positions manifestées à travers les valeurs, les avantages et les critiques que les Goncourt attribuent à ces techniques, à une époque où la caricature oscille entre les possibles de la gravure sur bois et les visées industrielles de la lithographie. [less ▲]

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See detailX-LAG ou comment ils sont devenus si grands ?
BECKERS, Albert ULiege

Scientific conference (2017, June 09)

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See detailEMT and inflammation: inseparable actors of cancer progression.
Suarez-Carmona, Meggy; Lesage, Julien; Cataldo, Didier ULiege et al

in Molecular Oncology (2017)

Tumors can be depicted as wounds that never heal, and are infiltrated by a large array of inflammatory and immune cells. Tumor-associated chronic inflammation is a hallmark of cancer that fosters ... [more ▼]

Tumors can be depicted as wounds that never heal, and are infiltrated by a large array of inflammatory and immune cells. Tumor-associated chronic inflammation is a hallmark of cancer that fosters progression to a metastatic stage, as has been extensively reviewed lately. Indeed, inflammatory cells persisting in the tumor establish a cross-talk with tumor cells that may result in a phenotype switch into tumor-supporting cells. This has been particularly well described for macrophages and is referred to as tumor-associated "M2" polarization. Epithelial-to-mesenchymal transition (EMT), the embryonic program that loosens cell-cell adherence complexes and endows cells with enhanced migratory and invasive properties, can be co-opted by cancer cells during metastatic progression. Cancer cells that have undergone EMT are more aggressive, displaying increased invasiveness, stem-like features and resistance to apoptosis. EMT programs can also stimulate the production of pro-inflammatory factors by cancer cells. Conversely, inflammation is a potent inducer of EMT in tumors. Therefore, the two phenomena may sustain each other, in an alliance for metastasis. This is the focus of this review, where the interconnections between EMT programs and cellular and molecular actors of inflammation are described. We also recapitulate data linking the EMT/inflammation axis to metastasis. [less ▲]

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See detailLe portrait-robot de l'élu(e) de demain
Geelkens, Mélanie; Grandjean, Geoffrey ULiege

Article for general public (2017)

Detailed reference viewed: 22 (2 ULiège)
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See detailSeparable states with infinitely many separable decompositions
Neven, Antoine ULiege; Bastin, Thierry ULiege

Poster (2017, June 09)

Despite intense effort in the past decades, developing a general criterion for identifying separable mixed states is still an open problem. In this context, the Positive Partial Transpose (PPT) criterion ... [more ▼]

Despite intense effort in the past decades, developing a general criterion for identifying separable mixed states is still an open problem. In this context, the Positive Partial Transpose (PPT) criterion constituted an important first step towards practical entanglement detection techniques and was later used to investigate the auxiliary problem of finding separable decompositions for separable states. In this poster, we use the rank diminishing method proposed by B. Kraus et al. [PRA 61, 062302 (2000)], that exploits the PPT property to reconstruct separable decompositions, to study the separable decompositions of symmetric PPT states of 3 qubits. We show that any 3-qubit symmetric product states always belong to an optimal separable decomposition of a PPT symmetric 3-qubit state with maximal birank. [less ▲]

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See detailThe roles of competition law in a regulated digital market environment: lessons (not) to learn from related fields of EU regulation
Van Cleynenbreugel, Pieter ULiege

Conference (2017, June 09)

Within the framework of its Digital Single Market (DSM) agenda, the European Union proposes the adoption of new legislative proposals aimed at removing remaining obstacles to digital transactions ... [more ▼]

Within the framework of its Digital Single Market (DSM) agenda, the European Union proposes the adoption of new legislative proposals aimed at removing remaining obstacles to digital transactions. Proposals relate to the abolition of geo-blocking as well as data and copyright portability. Complementing competition law provisions, those initiatives would seek to create the conditions for a competitive e-commerce environment within the EU internal market. In doing so, the Commission implicitly but clearly seeks to replicate a regulatory and policy approach it had taken already from the 1990s onwards when liberalising the energy and electronic communication sectors. It can be submitted that the European Commission, in proposing its DSM regulation strategy and in setting the terms of its e-commerce sector inquiry, has paid insufficient attention so far to the various and complementary roles competition law can play in a more strictly regulated market environment. In an attempt to clarify the scope and role of EU competition law and its enforcement in a digital single market environment and to guarantee its coherent application with the proposed DSM regulations, this paper will reflect on the roles competition law can our should still play in this context. Proceeding in three parts, the first part of the paper will chart the interaction between competition law and market regulation proposals in the EU’s DSM context. Using examples from the geo-blocking, data portability and copyright proposals made, this part highlights how the EU institutions perceive the interaction between competition law provisions and market regulation in this context. On the basis of that analysis, the second part will frame the interaction between competition law and market regulation as perceived in the DSM strategy, by comparing it with earlier examples in the realm of energy and electronic communications. In doing so, this part will identify two important similarities (breaking up barriers to trade and facilitating cross-border competition) as well as two fundamental differences (absence of natural monopolies and of intensely state regulated sectors). Acknowledging those similarities and differences, it will be submitted, allows better to conceptualise the role of competition law in the particular DSM context. To that extent, the third part will present and analyse the tenability of three possible roles competition law can still play against this background. Assessing the advantages and limits of each approach, that part will invite the Commission to take a clearer stance regarding the choice of one of them. [less ▲]

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See detailDeformations of soap bubbles in a uniform electric field
Mawet, Sébastien ULiege; Caps, Hervé ULiege; Dorbolo, Stéphane ULiege

Poster (2017, June 09)

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See detailSbCOMT (Bmr12) is involved in the biosynthesis of tricin-lignin in sorghum
Eudes, Aymerick; Dutta, Tanmoy; Deng, Kei et al

in PLoS ONE (2017), 12(6), 1-11

Lignin in plant biomass represents a target for engineering strategies towards the development of a sustainable bioeconomy. In addition to the conventional lignin monomers, namely p-coumaryl, coniferyl ... [more ▼]

Lignin in plant biomass represents a target for engineering strategies towards the development of a sustainable bioeconomy. In addition to the conventional lignin monomers, namely p-coumaryl, coniferyl and sinapyl alcohols, tricin has been shown to be part of the native lignin polymer in certain monocot species. Because tricin is considered to initiate the polymerization of lignin chains, elucidating its biosynthesis and mechanism of export to the cell wall constitute novel challenges for the engineering of bioenergy crops. Late steps of tricin biosynthesis require two methylation reactions involving the pathway intermediate selgin. It has recently been demonstrated in rice and maize that caffeate O-methyltransferase (COMT) involved in the synthesis syringyl (S) lignin units derived from sinapyl alcohol also participates in the synthesis of tricin in planta. In this work, we validate in sorghum (Sorghum bicolor L.) that the O-methyltransferase responsible for the production of S lignin units (SbCOMT / Bmr12) is also involved in the synthesis of lignin-linked tricin. In particular, we show that biomass from the sorghum bmr12 mutant contains lower level of tricin incorporated into lignin, and that SbCOMT can methylate the tricin precursors luteolin and selgin. Our genetic and biochemical data point toward a general mechanism whereby COMT is involved in the synthesis of both tricin and S lignin units. [less ▲]

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See detailUps and downs for SoTL development in a collective project targeting feedback practice enhancement
Verpoorten, Dominique ULiege; Detroz, Pascal ULiege; Mohr, Audrey ULiege et al

Conference (2017, June 08)

The “Feedback First-Year Project” (FFYP) was designed by IFRES (Institute for Training and Research in Higher Education) and the Study Guidance Service at the University of Liège (Belgium) to support ... [more ▼]

The “Feedback First-Year Project” (FFYP) was designed by IFRES (Institute for Training and Research in Higher Education) and the Study Guidance Service at the University of Liège (Belgium) to support First-Year professors’ efforts to think and act upon their current teaching and assessment practice, and possible improvements. Amongst lessons learnt, the presentation pinpoints three major risks that a collective project like FFYP might encounter. Recommendations likely to mitigate these risks are proposed, in case others would like to replicate the experience. [less ▲]

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See detailDiscovery and Characterization of R/S-N-3-Cyanophenyl-N'-(6-tert-butoxycarbonylamino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)urea, a New Histone Deacetylase Class III Inhibitor Exerting Antiproliferative Activity against Cancer Cell Lines
Schnekenburger, M; Goffin, Eric ULiege; Lee, J-Y et al

in Journal of Medicinal Chemistry (2017), 60(11), 4714-4733

A new series of N-aryl-N'-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)ureas bearing an alkoxycarbonylamino group at the 6-position were synthesized and examined as putative anticancer agents targeting ... [more ▼]

A new series of N-aryl-N'-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)ureas bearing an alkoxycarbonylamino group at the 6-position were synthesized and examined as putative anticancer agents targeting sirtuins in glioma cells. On the basis of computational docking combined to in vitro sirtuin 1/2 inhibition assays, we selected compound 18 [R/S-N-3-cyanophenyl-N'-(6-tert-butoxycarbonylamino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)urea] which displays a potent antiproliferative activity on various glioma cell types, assessed by quantitative videomicroscopy, eventually triggering senescence. The impact on normal glial cells was lower with a selectivity index of >10. Furthermore, human U373 and Hs683 glioblastoma cell lines served to demonstrate the inhibitory activity of 18 against histone deacetylase (HDAC) class III sirtuins 1 and 2 (SIRT1/2) by quantifying acetylation levels of histone and non-histone proteins. The translational potential of 18 was validated by an NCI-60 cell line screen and validation of growth inhibition of drug resistant cancer cell models. Eventually, the anticancer potential of 18 was validated in 3D glioblastoma spheroids and in vivo by zebrafish xenografts. In summary, compound 18 is the first representative of a new class of SIRT inhibitors opening new perspectives in the medicinal chemistry of HDAC inhibitors. [less ▲]

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See detailDéplacer pragmatiquement le débat sur la critique? Quelques gestes critiques pour repeupler le temps
Eliçabe, Rémi; Guilbert, Amandine; Pieron, Julien ULiege

Scientific conference (2017, June 08)

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See detailL'art de la médiation scolaire. Entre ambiguïté et interprétations
Dethier, Baptiste ULiege

Doctoral thesis (2017)

La thèse porte sur la construction de la politique de médiation scolaire menée en Belgique francophone et sa mise en œuvre concrète par de nouveaux agents chargés de l’interpréter : les médiateurs ... [more ▼]

La thèse porte sur la construction de la politique de médiation scolaire menée en Belgique francophone et sa mise en œuvre concrète par de nouveaux agents chargés de l’interpréter : les médiateurs scolaires. Dans un milieu scolaire où les acteurs, internes et externes aux établissements, sont multiples, les médiateurs sont appelés à prendre en charge des problèmes scolaires tels que la violence, le décrochage et l’absentéisme dans un cadre ambigu et, par conséquent, sujet à interprétation. La thèse rend compte du contexte organisationnel dans lequel les médiateurs s’inscrivent et de la mise en œuvre de cette politique. Baptiste Dethier analyse leur travail à l’aide de la métaphore du travail « artistique », c’est-à-dire comme un ensemble de procédures, de connaissances et de règles encadrant l’exercice d’une activité créative. Tout d’abord, cette activité est construite à partir d’orientations de sens – et non de prescriptions – données par l’État, les médiateurs scolaires étant chargés de les interpréter, grâce à une autonomie partiellement contrôlée. Ensuite, ces interprétations sont analysées grâce aux discours des médiateurs, reflétant la forte hétérogénéité dans la mise en œuvre de la politique de médiation scolaire ainsi que les controverses qui animent en permanence la fonction de médiateur. Enfin, à travers l’analyse des pratiques concrètes des médiateurs, il apparaît qu’elles consistent : d’une part, en la création de mises en scène spécifiques destinées à produire chez les bénéficiaires un état particulier de sensibilité ; d’autre part, comme autant de mises à l’épreuve de leur intégrité « artistique » et des principes dont ils se revendiquent. La thèse montre que les médiateurs scolaires se distinguent moins par ce qu’ils font que par la façon dont ils en parlent. Dès lors, la place de la place de la médiation et de la fonction de médiateur dans la division du travail au sein des organisations scolaires est questionnée. Celle-ci s’y trouve éclatée et ambigüe, entre contre-culture bousculant les équilibres historiques du système et participation au maintien de la forme scolaire traditionnelle. [less ▲]

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See detailRetours d’expérience d’un partenariat Université - Agences de l'Eau pour une gestion de la qualité des eaux de surface
Deliège, Jean-François ULiege; Everbecq, Etienne ULiege; MAGERMANS, POL ULiege et al

Conference (2017, June 08)

Un partenariat innovant a été établi entre une équipe de recherche universitaire (unité R&D de l’Aquapôle, Université de Liège) et des pouvoirs publics ayant dans leurs attributions la protection des ... [more ▼]

Un partenariat innovant a été établi entre une équipe de recherche universitaire (unité R&D de l’Aquapôle, Université de Liège) et des pouvoirs publics ayant dans leurs attributions la protection des ressources en eau et des milieux aquatiques (Agences de l’Eau françaises, Administrations wallonne et flamande). L’objectif principal de ce partenariat est la gestion des ressources par les Agences et Administrations en les dotant d’un outil innovant et opérationnel d’aide à la décision leur permettant de remplir leurs missions régionales (programmes d’intervention, SDAGE, …), nationales et internationales (DCE, rapportage européen, …). Pour atteindre cet objectif, le partenariat se base sur le développement d’une suite logicielle répondant aux attentes des opérateurs. Cette stratégie de développement, basée sur les besoins des partenaires, est au bénéfice direct de la restauration de la qualité des milieux aquatiques. [less ▲]

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