Last 7 days
Bookmark and Share    
Full Text
Peer Reviewed
See detailThe A2 gene of alcelaphine herpesvirus-1 is a transcriptional regulator affecting cytotoxicity in virus-infected T cells but is not required for malignant catarrhal fever induction in rabbits.
Parameswaran, Nevi; Dewals, Benjamin G ULg; Giles, Tom C. et al

in Virus research (2014)

Alcelaphine herpesvirus-1 (AlHV-1) causes malignant catarrhal fever (MCF). The A2 gene of AlHV-1 is a member of the bZIP transcription factor family. We wished to determine whether A2 is a virulence gene ... [more ▼]

Alcelaphine herpesvirus-1 (AlHV-1) causes malignant catarrhal fever (MCF). The A2 gene of AlHV-1 is a member of the bZIP transcription factor family. We wished to determine whether A2 is a virulence gene or not and whether it is involved in pathogenesis by interference with host transcription pathways. An A2 gene knockout (A2DeltaAlHV-1) virus, revertant (A2revAlHV-1) virus, and wild-type virus (wtAlHV-1) were used to infect three groups of rabbits. A2DeltaAlHV-1-infected rabbits succumbed to MCF, albeit with a delayed onset compared to the control groups, so A2 is not a critical virulence factor. Differential gene transcription analysis by RNAseq and qRT-PCR validation of a selection of these was performed in infected large granular lymphocyte (LGL) T cells obtained in culture from the MCF-affected animals. A2 was involved in the transcriptional regulation of immunological, cell cycle and apoptosis pathways. In particular, there was a bias towards gammadelta T cell receptor (TCR) expression and downregulation of alphabeta TCR. TCR signalling, apoptosis, cell cycle, IFN-gamma and NFAT pathways were affected. Of particular interest was partial inhibition of the cytotoxicity-associated pathways involving perforin and the granzymes A and B in the A2DeltaAlHV-1-infected LGLs compared to controls. In functional assays, A2DeltaAlHV-1-infected LGLs were significantly less cytotoxic than wtAlHV-1- and A2revAlHV-1-infected LGLs using rabbit corneal epithelial cells (SIRC) as targets. This implies that A2 is involved in a pathway enhancing the expression of LGL cytotoxicity. This is important as virus-infected T cell cytotoxicity in vivo has been suggested as a potential mechanism of disease induction in MCF. [less ▲]

Detailed reference viewed: 11 (4 ULg)
See detailDeception and the value of truth: a case study from the fifteenth century
Bauden, Frédéric ULg

Scientific conference (2014, April 13)

Detailed reference viewed: 27 (5 ULg)
Full Text
See detailWhat about Google Scholar when searching information in Human and Physical Geography?
Stirbu, Simona ULg

Conference (2014, April 12)

This study focuses on four bibliographic tools and aims to highlight what the use of the Google Scholar search engine can yield, in comparison with three commercial bibliographical databases: the well ... [more ▼]

This study focuses on four bibliographic tools and aims to highlight what the use of the Google Scholar search engine can yield, in comparison with three commercial bibliographical databases: the well known multidisciplinary database Web of Science (WoS); GeoRef, a specialized data base in geosciences; and FRANCIS, which includes international geographical bibliography. To identify the bibliographic references published yearly between the years 2005 to 2009, ten keywords placed between quotation marks have been searched through the title field of the search tool interfaces. On a monthly basis, from November 2010 to July 2011, an identical process was repeated to get some information on the repeatability of the searches. Initially the whole set of results was analysed, and then the search results of two keywords were studied in more details. The results indicate that GS provides a high overlap with the search results of the other databases, but also yields numerous unique hits. Moreover, it seems that it is also able to find diverse types of literature, while the others are more specialized. [less ▲]

Detailed reference viewed: 61 (14 ULg)
Full Text
See detailInfrared Holography
Georges, Marc ULg

Scientific conference (2014, April 11)

Detailed reference viewed: 7 (2 ULg)
See detailXenogeneic GVHD in NSG mice: focus on rapamycin
Ehx, Grégory ULg

Conference (2014, April 11)

Detailed reference viewed: 15 (4 ULg)
Full Text
See detail"Gefühltes Komma - richtiges Komma?"
Münzberg, Franziska ULg

Scientific conference (2014, April 11)

Detailed reference viewed: 11 (0 ULg)
Full Text
Peer Reviewed
See detailPhylogenetic study of Aedes albopictus and Aedes koreicus (Diptera, Culicidae) origin, two invasive mosquito species in Belgium
Raharimalala, Fara Nantenaina ULg; Boukraa, Slimane ULg; Bawin, Thomas ULg et al

Poster (2014, April 10)

The main ways of the introduction of invasive mosquito species in Europe were greatly facilitated by the importation of used tires and plants from the South of China (Dracaena sanderiana, called "Lucky ... [more ▼]

The main ways of the introduction of invasive mosquito species in Europe were greatly facilitated by the importation of used tires and plants from the South of China (Dracaena sanderiana, called "Lucky bamboo"), which are a very good breeding sites of these mosquitoes (www.eidatlantique.eu). For Belgium, several species of exotic mosquitoes have already been listed such as Ochlerotatus japonicus japonicus, Aedes albopictus and A. koreicus. We have captured one male of A. albopictus in Belgium in July 2013 (Boukraa et al, 2013), and teams from other entomologist have been able to find several individuals in the months that have followed our discovery (personal communication). However, his presence was reported first in 2000 (Schaffner et al. 2004) but until 2012, no individuals have been found (Versteirt et al., 2013). We also could find larvae of A. koreicus in abundance. These discovery suggest that these two invasive species are being established in Belgium. Methods: Adult mosquitoes were collected by CO2-baited traps Mosquito Magnet Liberty Plus (MMLP) and immature stages by the dipping method from 8 sites of Belgium. Each individual was then determined morphologically. For A. albopictus and A. koreicus, reconfirmation by molecular method was performed with COI and ND5 mitochondrial primers and sequences were then aligned with those of mosquitoes available in databases by using BioEdit and Multialn softwares. The two gene sequences were concatenated to improve the reliability of the phylogenetic analysis and were carried out by using the Seaview software based on maximum likelihood (ML) methods. Trees were then constructed with the general time reversible (GTR) model, and branch supports were estimated by bootstrapping with 1000 replicates. Result: The aim of this work will focus on the study of the probable origin of these two species of Aedes, which are for the moment safe yet, but that might become dangerous in the event of massive outbreak. The knowledge of the probably origin of the two invasive mosquitoes allow take more protection against their way to enter in the country. [less ▲]

Detailed reference viewed: 67 (4 ULg)
Full Text
Peer Reviewed
See detailSame-sex parenting is legal in Belgium but some heterosexuals support it and others don't: why?
Scali, Thérèse ULg; D'Amore, Salvatore ULg; Green, Robert-Jay

Poster (2014, April 10)

Gays and Lesbians represent between 7 and 10% of the Belgian population, this means 1 million of citizens. Notwithstanding the large number of civil rights granted to homosexuals and the anti ... [more ▼]

Gays and Lesbians represent between 7 and 10% of the Belgian population, this means 1 million of citizens. Notwithstanding the large number of civil rights granted to homosexuals and the anti-discrimination laws, the issue of social acceptance of same-sex couples and families remains. However, the attitude of the population (support vs. rejection and discrimination) and the marginalization of a minority influence not only their quality of life but also their couple and parenting skills and the development of their children (Armesto, 2002; Goldberg, 2010). Results show that attitudes towards same-sex parenting can be explained by four categories of arguments: arguments regarding children well-beeing, religious and political arguments, contact and experiential arguments and traditional arguments. [less ▲]

Detailed reference viewed: 24 (5 ULg)
Full Text
See detailCapire gli attegiamenti nei confronti degli omogenitori in Belgio
Scali, Thérèse ULg

Scientific conference (2014, April 10)

La situazione sociale per i genitori gay e lesbiche in Belgio. I predittori degli atteggiamenti positivi e negativi verso l’omogenitorialità. Le famiglie Rainbow in Belgio: cosa permette la legge? Miti e ... [more ▼]

La situazione sociale per i genitori gay e lesbiche in Belgio. I predittori degli atteggiamenti positivi e negativi verso l’omogenitorialità. Le famiglie Rainbow in Belgio: cosa permette la legge? Miti e stereotipi sulle famiglie omogenitoriali. Perché alcuni Belgi non sostengono gli omogenitori? Il ruolo del « benessere » del bambino. Cosa si può fare? [less ▲]

Detailed reference viewed: 13 (2 ULg)
Full Text
See detailParcelles expérimentales de la sylviculture d'arbres-objectifs
Perin, Jérôme ULg

Diverse speeche and writing (2014)

Présentation du réseau de dispositifs expérimentaux et de l'état des recherches de GxABT concernant la sylviculture d'Arbres-objectifs.

Detailed reference viewed: 16 (2 ULg)
Full Text
See detailUsages contrastés d'eCampus à l'ULg
Lecomte, Béatrice ULg; Schaffer, Patrick ULg

Scientific conference (2014, April 10)

Detailed reference viewed: 15 (1 ULg)
See detailA new perspective for investigation of sublethal concentrations of endocrine disruptors
Prodan, Irina; Esanu, Valentin Ovidiu; Petrescu-Mag, Ioan Valentin et al

Scientific conference (2014, April 10)

Detailed reference viewed: 14 (2 ULg)
See detailLe pilotage par les chiffres de la politique sportive belge francophone
Zeimers, Géraldine ULg

Conference (2014, April 10)

Detailed reference viewed: 8 (0 ULg)
See detailFaire les courses au quotidien. L’approvisionnement alimentaire d’un groupe de migrantes marocaines en Italie en temps de crise
Mescoli, Elsa ULg

Scientific conference (2014, April 10)

La crise généralisée qui, depuis quelques années, a affaibli les économies de nombre d’états, a eu des conséquences sur la typologie des migrations internationales : les trajectoires, les projets, les ... [more ▼]

La crise généralisée qui, depuis quelques années, a affaibli les économies de nombre d’états, a eu des conséquences sur la typologie des migrations internationales : les trajectoires, les projets, les destinations, les départs se sont modifiées en fonction de nouveaux facteurs auxquels les individus et les groupes étaient confrontés (Castles e Vezzoli 2009 ; Arango e González Quiñones 2009 ; Cornelius et al. 2010). A côté de ces macro-dynamiques globales, la crise a également engendré des changements dans la vie quotidienne des migrants lorsqu’ils étaient déjà partis et qu’ils s’étaient déjà installés ailleurs. Dans ce cadre, ma communication vise à analyser les pratiques d’approvisionnement alimentaire d’un groupe de migrantes marocaines en Italie mettant en place des stratégies (Certeau 1980 ; Sassen 2002 ; Rebughini and Sassatelli, 2008; Sassatelli 2009) pour faire face aux conséquences concrètes de la crise économique (notamment la diminution de leur pouvoir d’achat en conséquence de leur précarité professionnelle). Au travers de plusieurs déplacements dans la ville où elles habitaient et de la mobilisation des réseaux familiaux alimentant des circuits informels d’échange de biens, ces femmes satisfaisaient leurs différentes exigences – parmi lesquelles le désir de performer des préparations propres à leur mémoire incorporée – tout en répondant aux contraintes économiques déterminées par la crise. Ma tentative sera de démontrer qu’en dépit des difficultés rencontrées, ces femmes arrivaient à exercer une agency dans le nouvel espace vécu et à se positionner de façon active au travers de leurs choix et conduites quotidiennes. Mon analyse se basera sur les exemples collectés lors de ma recherche doctorale concernant les pratiques culinaires de femmes marocaines en contexte migratoire, et elle sera également supportée par des éléments visuels exprimant la matérialité des dynamiques objets d’étude. [less ▲]

Detailed reference viewed: 23 (1 ULg)