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See detailRisques et défis sécuritaires de la (non)-intégration des Balkans occidentaux dans l’Union européenne
Lika, Liridon ULg

in Wintgens, Sophie; Grandjean, Geoffrey; Vanhaeren, Stéphanie (Eds.) L’insécurité en question : définition, enjeux et perspectives (2015)

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See detailComplementary approaches for the numerical simulation of the Micro- Plasto-Hydrodynamic Lubrication regime
Hubert, Cédric; Dubois, André; Dubar, Laurent et al

in Key Engineering Materials [=KEM] (2015), 651-653

This paper presents recent investigations in the field of lubricant escapes from asperities. This phenomenon, named Micro Plasto Hydrodynamic Lubrication (MPHL), induces friction variation during metal ... [more ▼]

This paper presents recent investigations in the field of lubricant escapes from asperities. This phenomenon, named Micro Plasto Hydrodynamic Lubrication (MPHL), induces friction variation during metal forming processes. A better understanding of MPH lubrication would lead to a better management of friction, which is a central element in most sheet metal forming processes. To fulfil that goal, experiments were conducted in plane strip drawing using a transparent upper tool in order to observe lubricant flow around macroscopic pyramidal cavities. These experiments were then numerically reproduced with two complementary Finite Element models. The numerical results are discussed in this paper and show good agreement with experimental measurements. [less ▲]

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See detailIntro Nudge and the Law final
Sibony, Anne-Lise ULg; Alemano, Alberto

in Sibony, Anne-Lise; Alemano, Alberto (Eds.) Nudge and the Law: A European Perspective (2015)

Nudge and the Law explores the legal implications of the emergent phenomenon of behaviourally informed intervention. It focuses on the challenges and opportunities it may offer to the policymaking of the ... [more ▼]

Nudge and the Law explores the legal implications of the emergent phenomenon of behaviourally informed intervention. It focuses on the challenges and opportunities it may offer to the policymaking of the European Union. This dual focus on law and on Europe characterises our endeavour. This volume has been structured by taking as a point of the departure the current nudging debate, which mainly comprises two strands of enquiry: when is it legitimate for States to use psychology to inform policy? (the legitimacy debate) and, to the extent that it is legitimate, how can behavioural insights in practice be incorporated into the decision making processes? (the practicability debate). Against this backdrop we brought together scholars who could analyse what behavioural insights might bring to EU law, both at a horizontal level and at a sectoral level. This volume endeavours to present the results of their research in a manner that is accessible both to EU law specialists who are not yet familiar with behavioural sciences and to behavioural lawyers who are not specialists in EU law. [less ▲]

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See detailEffects of a high-fibre diet on ammonia and greenhouse gas emissions from gestating sows and fattening pigs
Philippe, François-Xavier ULg; Laitat, Martine ULg; Wavreille, José et al

in Atmospheric Environment (2015), 109

This study aims to measure under barn conditions the emissions of NH3, N2O, CH4 and CO2 associated with gestating sows (trial 1) and fattening pigs (trial 2) fed either a control diet (CTD) based on ... [more ▼]

This study aims to measure under barn conditions the emissions of NH3, N2O, CH4 and CO2 associated with gestating sows (trial 1) and fattening pigs (trial 2) fed either a control diet (CTD) based on cereals or a high-fibre diet (HFD) based on sugar beet pulp (SBP). Three successive batches of 10 Belgian Landrace gestating sows were used for trial 1. Two successive batches of 24 Pi etrain Belgian Landrace fattening pigs were used for trial 2. Animals were kept on slatted floor. The gas emissions were measured by infrared photoacoustic detection and expressed per day and per livestock unit, equals to 500 kg body weight. Similar trends were observed for both animal types. With HFD, the NH3 emissions were reduced (27.2 vs. 36.5 g for the gestating sows, P < 0.001; 23.2 vs. 45.0 g for the fattening pigs, P < 0.001) but the CH4 emissions were increased (41.5 vs. 21.0 g for gestating sows, P < 0.001; 37.9 vs. 27.2 g for fattening pigs, P < 0.001). The fibre content of the diet had not significant impact on N2O emissions (around 1.4 g for gestating sows and 2.1 g for fattening pigs, P > 0.05), and on CO2 emissions (around 6.0 kg for gestating sows and 9.1 kg for fattening pigs, P > 0.05). Most of manure parameters did not statistically differ regarding the treatment. Reproductive performance and body condition of the sows were not affected by the diet. However, growth performance and carcass traits of the HFD-fed fattening pigs were deteriorated compared to CTD. [less ▲]

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See detailConclusion Nudge and the Law final
Sibony, Anne-Lise ULg; Alemano, Alberto

in Sibony, Anne-Lise; Alemano, Alberto (Eds.) Nudge and the Law: A European Perspective (2015)

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See detailEU Consumer Protection and Behavioural Sciences
Sibony, Anne-Lise ULg; Helleringer, Geneviève

in Sibony, Anne-Lise; Alemano, Alberto (Eds.) Nudge and the Law: A European Perspective (2015)

In this chapter, we review the behavioural critique of EU consumer legislation and focus is on how behavioural insights are being incorporated or could realistically be incorporated in existing or new ... [more ▼]

In this chapter, we review the behavioural critique of EU consumer legislation and focus is on how behavioural insights are being incorporated or could realistically be incorporated in existing or new rules. Behavioural scholars sometimes present EU consumer law as archaic and counter-productive and this creates a diffuse view that a behavioural turn would constitute a revolution for EU consumer law. We do not subscribe to this view. We begin by putting the current legitimacy crisis of EU consumer law in perspective. Specifically, we explain why EU law evolved to be an apparent anti-model of behavioural regulation and discuss whether the internal market constraints that still exist prevent a behavioural turn. We conclude that they do not. We illustrate this claim in relation to disclosure mandates. The central feature of disclosure mandates in EU consumer law has been severely criticised in the light of behavioural findings. We agree that they are over-used but find that disclosure mandates, as a technique, can still serve a useful purpose and suggest how their use can be streamlined. We also point out that recent developments tend to make disclosures smarter and point to directions to pursue this evolution. Finally, we turn to the core message of behavioural insights to policy makers: ‘make it simple’ and analyse how it has been received in EU consumer law beyond the specific issue of disclosure. We find evidence of an intention to simplify which predates the current commitment of the Commission to make simplification a priority, but highlight that efforts to simplify have led to half-baked solutions that are not simple enough. We conclude that EU consumer law does not need a revolution but a continued reform and that it contains the seeds of a more behavioural approach. [less ▲]

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See detailEuropean Construction Law
Kohl, Benoît ULg; Chao-Duvis, Monika; Hillig, J. et al

Book published by European Society of Construction Law (2015)

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See detailChemical composition and antibacterial activitiy of the essential oils of Algerian Myrtus communis L.
Hennia, Aïcha; Brada, Moussa; Nemmiche, Saïd et al

in Journal of Essential Oil Research (2015)

Myrtus communis L. leaf essential oils from Algeria were analyzed by gas chromatography (GC) and gas chromatography/mass spectrometry (GC/MS). A total of thirty-four components were identified accounting ... [more ▼]

Myrtus communis L. leaf essential oils from Algeria were analyzed by gas chromatography (GC) and gas chromatography/mass spectrometry (GC/MS). A total of thirty-four components were identified accounting for 95% of the oil. The main compounds were limonene (23.4%), linalool (15.4%), geranyl acetate (10.9%), α-pinene (10.7%), linalyl acetate (8.2%) and 1,8-cineole (6.6%).The antimicrobial evaluation showed that myrtle oil exhibited good antibacterial activity against Staphylococcus aureus, Proteus mirabilis and Kleibsiella pneumonia, but differed according to the strains. Conversely, it was not active against Pseudomonas aeruginosa. [less ▲]

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See detailSelf-knowledge
D'Argembeau, Arnaud ULg

in Toga, A. W. (Ed.) Brain mapping: An encyclopedic reference (2015)

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See detailDroit de la fonction publique locale, Bruxelles, Flandre, Wallonie
Durviaux, Ann-Lawrence ULg; Fisse, Damien

Book published by Larcier (2015)

Etude de droit comparé régional relatif au statut des grades légaux au sein des pouvoirs locaux

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See detailNovel magneto-electric multiferroics from first-principles calculations
Varignon, Julien ULg; Bristowe, Nicholas ULg; Bousquet, Eric ULg et al

in Comptes Rendus Physique (2015), 16

Interest in first-principles calculations within the multiferroic community has been rapidly on the rise over the last decade. Initially considered as a powerful support to explain experimentally observed ... [more ▼]

Interest in first-principles calculations within the multiferroic community has been rapidly on the rise over the last decade. Initially considered as a powerful support to explain experimentally observed behaviours, the trend has evolved and, nowadays, density functional theory calculations have become also an essential predicting tool for identifying original rules to achieve multiferroism and design new magneto-electric compounds. This chapter aims at highlighting the key advances in the field of multiferroics, to which first-principles methods have contributed significantly. The essential theoretical developments that made this research possible are also briefly presented. [less ▲]

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See detailPhenotype Classification of Zebrafish Embryos by Supervised Learning
Jeanray, Nathalie ULg; Marée, Raphaël ULg; Pruvot, Benoist et al

in PLoS ONE (2015), 10(1), 01169891-20

Zebrafish is increasingly used to assess biological properties of chemical substances and thus is becoming a specific tool for toxicological and pharmacological studies. The effects of chemical substances ... [more ▼]

Zebrafish is increasingly used to assess biological properties of chemical substances and thus is becoming a specific tool for toxicological and pharmacological studies. The effects of chemical substances on embryo survival and development are generally evaluated manually through microscopic observation by an expert and documented by several typical photographs. Here, we present a methodology to automatically classify brightfield images of wildtype zebrafish embryos according to their defects by using an image analysis approach based on supervised machine learning. We show that, compared to manual classification, automatic classification results in 90 to 100 % agreement with consensus voting of biological experts in nine out of eleven considered defects in 3 days old zebrafish larvae. Automation of the analysis and classification of zebrafish embryo pictures reduces the workload and time required for the biological expert and increases the reproducibility and objectivity of this classification. [less ▲]

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See detailFair Trade and Social Enterprise
Huybrechts, Benjamin ULg

in Raynolds, Laura; Bennett, Elizabeth (Eds.) The Handbook of Research on Fair Trade (2015)

This chapter suggests that the notion of ‘social enterprise’ is useful to capture the DNA of organizations focused on fair trade and to locate them within a broader organizational taxonomy. Without ... [more ▼]

This chapter suggests that the notion of ‘social enterprise’ is useful to capture the DNA of organizations focused on fair trade and to locate them within a broader organizational taxonomy. Without seeking to impose a new term that may not resonate for certain actors or regions, this chapter aims to bring two contributions to fair trade research and practice. First, it is suggested that the social enterprise approach is particularly useful as an analytical tool enabling researchers and other stakeholders to capture the evolution and diversification of organizational models in fair trade. Second, the use of a broader organizational approach that is not specific to the sole fair trade sector allows for connections with similar organizations in other sectors and brings a shift from considering mainly what the organizations do (fair trade in this case) towards also addressing what they are (innovative social enterprise models combining market dynamics with social purpose). This chapter is structured as follows. First, the concept of social enterprise is introduced and discussed. Then, the evolution of the organizational landscape of fair trade (in the North) is summarized. Finally, fair trade organizations are examined in the light of the social enterprise concept, with illustrations from a study in four European countries (Huybrechts 2010a; 2012). [less ▲]

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See detailTrifles for 'Unflemings'. Teaching Dutch Literary History in Nineteenth-Century Wallonia
Steyaert, Kris ULg

in Van Kalmthout, T.; Zuidervaart, H. (Eds.) The Practice of Philology in the Nineteenth-Century Netherlands (2015)

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See detailUpdate on the role of extracorporeal CO2 removal
MORIMONT, Philippe ULg; BATCHINSKY, Andriy; LAMBERMONT, Bernard ULg

in Critical Care (2015)

This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2015 and co-published as a series in Critical Care. Other articles in the series can be found ... [more ▼]

This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2015 and co-published as a series in Critical Care. Other articles in the series can be found online at http://ccforum.com/series/annualupdate2015. Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www.springer.com/series/8901. [less ▲]

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See detailA Membrane-Type-1 Matrix Metalloproteinase (MT1-MMP) - Discoidin Domain Receptor 1 Axis Regulates Collagen-Induced Apoptosis in Breast Cancer Cells.
Assent, Delphine; Bourgot, Isabelle ULg; Hennuy, Benoît ULg et al

in PloS one (2015), 10(3), 0116006

During tumour dissemination, invading breast carcinoma cells become confronted with a reactive stroma, a type I collagen-rich environment endowed with anti-proliferative and pro-apoptotic properties. To ... [more ▼]

During tumour dissemination, invading breast carcinoma cells become confronted with a reactive stroma, a type I collagen-rich environment endowed with anti-proliferative and pro-apoptotic properties. To develop metastatic capabilities, tumour cells must acquire the capacity to cope with this novel microenvironment. How cells interact with and respond to their microenvironment during cancer dissemination remains poorly understood. To address the impact of type I collagen on the fate of tumour cells, human breast carcinoma MCF-7 cells were cultured within three-dimensional type I collagen gels (3D COL1). Using this experimental model, we have previously demonstrated that membrane type-1 matrix metalloproteinase (MT1-MMP), a proteinase overexpressed in many aggressive tumours, promotes tumour progression by circumventing the collagen-induced up-regulation of BIK, a pro-apoptotic tumour suppressor, and hence apoptosis. Here we performed a transcriptomic analysis to decipher the molecular mechanisms regulating 3D COL1-induced apoptosis in human breast cancer cells. Control and MT1-MMP expressing MCF-7 cells were cultured on two-dimensional plastic plates or within 3D COL1 and a global transcriptional time-course analysis was performed. Shifting the cells from plastic plates to 3D COL1 activated a complex reprogramming of genes implicated in various biological processes. Bioinformatic analysis revealed a 3D COL1-mediated alteration of key cellular functions including apoptosis, cell proliferation, RNA processing and cytoskeleton remodelling. By using a panel of pharmacological inhibitors, we identified discoidin domain receptor 1 (DDR1), a receptor tyrosine kinase specifically activated by collagen, as the initiator of 3D COL1-induced apoptosis. Our data support the concept that MT1-MMP contributes to the inactivation of the DDR1-BIK signalling axis through the cleavage of collagen fibres and/or the alteration of DDR1 receptor signalling unit, without triggering a drastic remodelling of the transcriptome of MCF-7 cells. [less ▲]

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See detailCharacterization of collagen fibrils after equine suspensory ligament injury: an ultrastructural and biochemical approach
Shikh Al Sook, Mohamad Khir ULg; Gabriel, Annick ULg; Salouci, Moustafa et al

in The Veterinary Journal (2015)

Suspensory ligament (SL) injuries are an important cause of lameness in horses. The mechanical properties of connective tissue in normal and pathological ligaments are mainly related to the fibril ... [more ▼]

Suspensory ligament (SL) injuries are an important cause of lameness in horses. The mechanical properties of connective tissue in normal and pathological ligaments are mainly related to the fibril morphology, as well as the collagen content and types. The purpose of this study was to evaluate, using biochemical and ultrastructural approaches, the alterations in collagen fibrils after injury. Eight Warmblood horses with visible signs of injury in only one forelimb SL were selected and specimens were examined by transmission electron microscope (TEM). Collagen types I, III and V were purified by differential salt precipitation after collagen extraction with acetic acid containing pepsin. TEM revealed abnormal organization as well as alterations in the diameter and shape of fibrils after SL injury. The bands corresponding to types I, III and V collagen were assessed by densitometry after sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE). Densitometric analysis indicated that the proportions of type III and type V collagen were significantly higher (P <0.001) in damaged tissues compared to normal tissues with a mean increase of 20.9 and 17.3% respectively. Concurrently, a significant decrease (P <0.001) in type I collagen within damaged tissues was recorded with a mean decrease of 15.2%. These alterations could be the hallmark of a decrease in the tissue quality and mechanical properties of the ligament. This provides new insight for subsequent research on tissue regeneration that may lead to the development of future treatment strategies for SL injury. [less ▲]

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See detailApprendre l'Histoire en faisant de l'histoire : Pie XII et la "Solution Finale"
Jadoulle, Jean-Louis ULg

in CORNET, Jacques; DARO, Sabine (Eds.) Voir double pour mieux comprendre. Outils didactiques pour la formation des enseignants en sciences et sciences humaines (2015)

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See detailFrom Alexander to the Theoi Adelphoi: Foundation and Legitimation of a Dynasty
Caneva, Stefano ULg

Book published by Peeters (2015)

This book provides a cultural and social history of the rise and legitimation of the concept of dynastic continuity in the early history of the Ptolemaic Empire. The scope of the study is therefore ... [more ▼]

This book provides a cultural and social history of the rise and legitimation of the concept of dynastic continuity in the early history of the Ptolemaic Empire. The scope of the study is therefore neither to provide a general overview of third-century Ptolemaic history, nor to discuss in detail the administrative and economic structures of the Ptolemaic state. Rather, its purpose is to investigate the ways by which the first Ptolemies negotiated and constructed a representation of their power as a dynastic house aspiring to universal dominion, protected by the gods and legitimately continuing the heritage of the Macedonian and Egyptian monarchies. It is argued that they managed to do so by operating within different socio-cultural and ethnic milieus and by pursuing their strategies on a two-fold level: on the one hand, by continuously reshaping the relationship between the present events of the ruling house and its historical and mythical past, so as to adapt it to new political and cultural agendas; on the other hand, by shifting the border between the spheres of human and divine power in order to ensure themselves the legitimacy and loyalty stemming from religious thought and practice. Discussed evidence comprises Greek and Egyptian sources, literary and documentary texts, iconographic and archaeological evidence from the Macedonian conquest of Egypt under Alexander to the ascension of Ptolemy III Euergetes. Whenever possible, a new, encompassing evaluation of old evidence has gained new impetus from the intensive analysis of newly published sources. Secondly, the complex cultural and social factors operating in the construction and legitimation of the Ptolemaic dynasty have been discussed by drawing on the contribution of up-to-date scholarship in cultural and religious history as well as in sociology. The rooting of Ptolemaic power in Egypt and the Eastern Mediterranean is studied as the movement from the immediate but unstable right of conquest established by Alexander, and subsequently claimed by the satrap Ptolemy, to the development of a mature and coherent system of power practices and representations. The structure of the book is meant to provide readers with a chronological and thematic discussion ranging from Alexander’s conquest of Egypt to the first years of Ptolemy III. However, the six chapters that constitute this study can also be read separately as they are conceived as the monographic treatment of major moments or aspects of the cultural, political, and religious history of the early Hellenistic period. Chapter 1 deals with the premises of Ptolemaic power in Egypt by focusing on the time of Alexander’s conquest. The implications of Alexander’s sonship to Zeus Ammon in propaganda and in religion are reviewed by drawing attention to the plurality of audiences (Macedonians, Greeks, Egyptians) for which this motif was conceived and used. Chapter 2 discusses the conflicting patterns of legitimation in the age of the Successors and how Ptolemy exploited them in his rise from satrap to king. Some seminal moments of Ptolemy’s career are re-examined: the acquisition of Alexander’s corpse as a source of embodied legitimacy; the interactions between the leader and pre-existing Macedonian and Egyptian elites as they appear in assembly scenes of Greek historiography and in the hieroglyphic Satrap stele; Ptolemy’s help to the Rhodians against Antigonus and Demetrius and the entanglement between royal charisma and religious honours. Chapter 3 focuses on the figure of Dionysus in Ptolemaic religion and culture from a twofold perspective. Firstly, the chapter provides an innovative analysis of the religious and ideological role of Dionysus in Ptolemy II’s Alexandrian procession described by Callixeinus of Rhodes. Secondly, it aims at offering a contribution for a reappraisal of the figure of Dionysus, of his cults and of the role of his figure within the larger context of the Ptolemaic Empire in the third century BC. Chapter 4 discusses the patterns of divinization of Arsinoe II within the royal couple through the most complete documentary dossier collected thus far on the subject. Rather than constituting the aim of the research, the debate concerning the chronology of Arsinoe’s death and divinization has provided the rough framework for a new investigation of how the image of a solid royal couple was invented and spread in religious life and in propaganda. Diachronic developments in the configurations of the dynastic couple are traced through Greek and Egyptian evidence and discussed in relation to the changing of political agendas during the reign of Ptolemy II. Chapter 5 studies the contribution of Ptolemy III to the construction of Ptolemaic dynastic continuity through old and new evidence, notably by providing fresh observations concerning the recently published decree of Alexandria (243 BC) for the understanding of Ptolemaic royal festivals in general and, more in particular, for the history of the festival Ptolemaia in the second half of the 3rd century BC. Chapter 6 breaks with chronological continuity to trace, through literary and documentary evidence from the Roman period, the development of the tradition envisaging Alexander’s body as a talismanic relic protecting the city of Alexandria. The purpose of this epilogue is to provide a methodological essay of interpretation of cultural traditions in the longue durée, when patterns of continuity developed under the Ptolemies were separated from their original context of diffusion and consequently were re-used to shape the civic identity of Alexandria within the new and broader framework of the Roman Empire. Although focus on the construction of a dynasty as a sequence of legitimate, kindred holders of monarchic power makes Ptolemaic kings and queens the central object of this study, it is argued that sovereigns cannot be considered as the sole holders of the initiative in the political, ideological and religious processes relating to the construction of royal and dynastic imagery. On the contrary, it appears that social agents other than the holders of supreme leadership not only reacted to top-down stimulation, but they also constructed, for their own use, representations of the monarchs that interacted with the message issued by the central power. From this perspective, therefore, dynastic continuity results from the intertextual combination of a variety of ideological and religious motifs stemming from different agents and occasions of communication. [less ▲]

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