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See detailGreek and Latin en the Roman World (100 to 700 AD)
Rochette, Bruno ULg

in Cambridge History of Later Latin Literature (in press)

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See detailElaboration of drug nanocarriers based on a glucosamine labeled amphiphilic polymer
Boyère, Cédric; Duhem, N; Debuigne, Antoine ULg et al

in Polymer Chemistry (in press)

A new functional polymer micelle with high loading efficiency of a poorly soluble drug was made of biocompatible and/or biosourced compounds, i.e. cholesterol-poly(ethylene glycol)-glucosamine (Chol-PEG ... [more ▼]

A new functional polymer micelle with high loading efficiency of a poorly soluble drug was made of biocompatible and/or biosourced compounds, i.e. cholesterol-poly(ethylene glycol)-glucosamine (Chol-PEG-GlcNH2). A synthesis strategy combining enzymatic and metal-free click chemistry was developed in order to meet the increasingly stringent requirements of biomedical applications. After the self-assembly of the Chol-PEG-GlcNH2 amphiphilic polymer in water, the presence of glucosamine at the micelle surface confers an active targeting moiety to the nanocarriers whereas protonation of the peripheral primary amine delay their aggregation. The complete characterization of this novel functional amphiphilic bioconjugate is presented as well as its aqueous solution behaviour and encapsulation efficiency using ketoconazole as a model hydrophobic drug. [less ▲]

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See detailCultural Marxism in the Anglo-Saxon radical right literature
Jamin, Jérôme ULg

in Jackson, Paul (Ed.) The Postwar Anglo-American Far Right: A Special Relationship of Hate (in press)

This chapter will analyze the place of the threat alleged of Cultural Marxism in the discourse of the radical and extreme right, in the United States as well as in continental Europe and the United ... [more ▼]

This chapter will analyze the place of the threat alleged of Cultural Marxism in the discourse of the radical and extreme right, in the United States as well as in continental Europe and the United Kingdom. The underlying aim of this chapter is to examine the determinant role that this ‘threat’ plays in the Anglo Saxon extreme right, in particular at the intellectual, ideological and doctrinal levels, in comparison to other countries. Certainly if the Netherlands, France or other countries have parties or political groups which borrow the rhetoric of ‘fighting’ against Cultural Marxism, or its more nebulous variant, ‘political correctness’, it certainly finds its origins in the United States, and more broadly the Anglo-Saxon world. To achieve this, the chapter will begin by unpicking the meanings behind the notion of Cultural Marxism, from its origins to its use in Anders Breivik’s manifesto released shortly before the Oslo and UtØya massacres. It will show that the term emerged from the literature of American ultraconservatives following the fall of the Berlin Wall as a consequence of the disappearance of the ‘red menace’ of Communism. Secondly, it will focus on two important moments in the development of the term. It will describe the phrase’s usage from the beginning of the 2000s within the discourse of Pat Buchanan, a political commentator and multiple U.S. presidential candidate. Then it will illustrate the re-emergence of the term some 10 years later, in the manifesto of Anders Breivik and in the subsequent justification of his acts throughout his trial. In both cases, we will see that Buchanan and Breivik emphasize the same basic theme, Cultural Marxism, in their denouncement of what they see as two different threats. Finally, from these explorations of the usage of the term, the discussion will examine other current uses of the notion of ‘Cultural Marxism’ in the British and American radical right. To conclude, it will show how the ‘Cultural Marxism’ threats are used by a variety of activists to argue for the defence of their political standpoints, setting this in a language of preserving freedom and democracy, but ultimately only within a framework designed to defend Judeo-Christian values. [less ▲]

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See detailDevelopmental defects in zebrafish for classification of EGF pathway inhibitors.
Pruvot, Benoist ULg; Curé, Yoann ULg; Djiotsa, Joachim et al

in Toxicology and Applied Pharmacology (in press)

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See detailBook review: Book, L. & Phillips, D. P. (2013), Creativity and entrepreneurship: Changing currents in education and public-life, Edward Elgard, Cheltenham, UK.
Dufays, Frédéric ULg

in International Journal of Entrepreneurial Behaviour and Research (in press), 20(3),

Looking at how to foster creativity and innovation for economic and social value, Lynn Book and David Phillips suggest bridging arts and sciences both within the academy and with external partners as a ... [more ▼]

Looking at how to foster creativity and innovation for economic and social value, Lynn Book and David Phillips suggest bridging arts and sciences both within the academy and with external partners as a key element. In this book, they compile a series of contributions that analyse, share experiences, model such (cross-sector) partnerships. [less ▲]

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See detailThe RIAD peptidomimetic inhibits HIV-1 replication in humanized NSG mice
Singh, Maneesh; Singh, Pratibha; Vaira, Dolores et al

in European Journal of Clinical Investigation (in press)

Background Increased intracellular concentration of cyclic AMP (cAMP) in T cells is associated with various immunodeficiency conditions including human immunodeficiency virus (HIV) infection. Several ... [more ▼]

Background Increased intracellular concentration of cyclic AMP (cAMP) in T cells is associated with various immunodeficiency conditions including human immunodeficiency virus (HIV) infection. Several reports indicate a critical role of activated protein kinase A (PKA) in the susceptibility of cells to HIV infection. We have used a cell permeable, stable peptidomimetic version (P3) of the RI-anchoring disruptor (RIAD), which prevents PKA interaction with A-kinase-anchoring proteins (AKAPs). It is known that RIAD peptide abrogates effects of localized cAMP signalling through anchored type I PKA in lymphocytes and prevents murine AIDS (MAIDS) infection when expressed as a transgene in mice. Methods and Results In vitro HIV-infected human peripheral blood mononuclear cells (PBMCs) show reduced levels of p24 and intracellular cAMP in T cells when treated with RIAD peptidomimetic (RIAD-P3). Humanized NOD/SCID/IL2cnull (NSG) mice infected with HIV-1 JRCSF and treated with RIAD-P3 (3􏰀5 mg) once every 2 weeks showed significantly reduced levels of viral load at +28, +42 and +56 days and increased CD4 numbers at +56 days after the start of treatment. RIAD-P3-treated humanized mice had lower levels of intracellular cAMP in T cells sorted from splenocytes. Conclusions Treatment with RIAD-P3 limits HIV-1 viral replication and stabilizes CD4 levels by mechanisms involving cAMP/PKA-I pathway in human PBMCs and humanized NSG mice. [less ▲]

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See detailThe BNP and the FN. Between Islamophobia and the “defence” of democratic values
Jamin, Jérôme ULg

in Jackson, Paul (Ed.) The British Far Right in Transition: 1945 to Today (in press)

In this article Jérôme Jamin examines the ideological development of the British National Party (BNP) and the Front National (FN) since 9/11. He argues that if both parties have evolved towards discourses ... [more ▼]

In this article Jérôme Jamin examines the ideological development of the British National Party (BNP) and the Front National (FN) since 9/11. He argues that if both parties have evolved towards discourses more in line with democracy and liberal values, it can be explained by the opportunity the “threat” of Islam offered. After a reminder of the birth and the electoral evolution of the two parties, Jamin focuses on the perception and the definition of democracy as depicted in their manifestos and main public speeches. The study reveals an ethnic-styled perception of democracy at the BNP in opposition with a more civic perception at the FN, even if the analysis shows an ambiguity behind the use of the concept of “people” in the FN rhetoric mixing frequently “demos” and “ethnos”. The author confronts the combination of this new democratic rhetoric with the birth of Islam as a threat incompatible with “British democracy” in the United Kingdom and “Republican secularism” in France. In both parties, stereotypes of Islam are used to portray the BNP and the FN as defenders of a true and legitimate democracy and to a great extent, Jamin argues, “Islam” provided an unexpected opportunity to replace migrants, foreigners and Arabs with a new stereotype: the Muslim who threatens the separation between state and religion, equality between men and women, freedom of speech, and so on. Jamin concludes by emphasising that both parties required time to identify this new scapegoat. [less ▲]

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See detailMircea Eliade et la pensée mythique au Paléolithique supérieur
Noiret, Pierre ULg

in Chirica, Vasile (Ed.) Vivre et mourir dans la Préhistoire et la Protohistoire de l'Europe (in press)

Avec le Paléolithique supérieur, de nombreuses données éclairent les fonctions symboliques. Au-delà des seules activités techniques, il est possible de restituer certains éléments d’une pensée mythique ... [more ▼]

Avec le Paléolithique supérieur, de nombreuses données éclairent les fonctions symboliques. Au-delà des seules activités techniques, il est possible de restituer certains éléments d’une pensée mythique, analogue à celle décrite par les ethnologues ou les historiens des religions. Leur étude ne permet pas de retrouver les mythes racontés, mais bien d’envisager lucidement leur nature et leur rôle fondamental pour le fonctionnement des sociétés paléolithiques. Dans les années 1990, la découverte de la grotte Chauvet a remis en cause l’évolution linéaire de l’art pariétal établie par André Leroi-Gourhan. La découverte récente de peintures très similaires en Roumanie, dans la grotte de Coliboaia, permet de compléter l’approche des phases initiales de cet art. Les similitudes entretenues entre les images de ces deux grottes poussent à retourner vers la notion de mythe. [less ▲]

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See detailArrêt(s) sur image(s) : usages et pratiques du photogramme
Thonon, Jonathan ULg

in MethIS : Méthodes et Interdisciplinarité en Sciences Humaines (in press)

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See detailVitamin D status of schoolchildren in Northern Algeria, seasonal variations and determinants of vitamin D deficiency
Djennane, M; Lebbah, S; Roux, C et al

in Osteoporosis International (in press)

Summary There are no published data on the vitamin D status of children living in North Africa. In 435 healthy Algerian children 5–15 years old, we found that vitamin D insufficiency (serum 25 ... [more ▼]

Summary There are no published data on the vitamin D status of children living in North Africa. In 435 healthy Algerian children 5–15 years old, we found that vitamin D insufficiency (serum 25-hydroxyvitamin D (25OHD) <50 nmol/L) was frequent, especially in winter. Low vitamin D status was associated with increased parathyroid hormone (PTH) and leg deformation Introduction As there are no published data on the vitamin D status of children living in North Africa, we evaluated the 25OHD concentration of healthy Algerian children at the end of summer and at the end of winter. As secondary objectives, we studied the various determinants of vitamin D status and the PTH-25OHD relationship in these subjects. Methods Four hundred thirty-five children 5–15 years old were examined and had a blood sample in September 2010. Of them, 408 were sampled again in March 2011. Results Median 25OHD concentration in the whole group was 71.4 nmol/L in September and 52.9 nmol/L in March. In September, 58.4, 29.9, and 8.1 % had a 25OHD concentration below 75, 50, and 30 nmol/L respectively. In March, these percentages increased to 65.2, 41.4, and 17.4 % for the 75, 50, and 30 nmol/L threshold, respectively. In multivariate analysis, older age, darker skin phototype, low daily vitamin D and calcium intake, poor socioeconomic status, and short daily sun exposure remained significantly associated with a 25OHD <50 nmol/L at both visits. In 72 (16.6 %) children, genu varum/valgum was present. Compared to the 363 children without leg deformation, they presented more frequently with the risk factors of vitamin D insufficiency. They also had lower 25OHD concentrations and higher PTH and tALP. Serum PTH and 25OHD concentrations were negatively and significantly correlated (r=−0.43; p<0.001) without a 25OHD threshold above which PTH does not decrease anymore. Conclusion Despite a sunny environment, vitamin D insufficiency is frequent in healthy Algerian children. [less ▲]

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See detailProcédés et enjeux de l'écriture polémique dans le dossier épistolaire anti-adoptianiste du concile de Francfort (794)
Close, Florence ULg; Veyrard-Cosme, Christiane

in Actes du colloque international ""Écriture et genre épistolaires, IVe-XIe s". 5-8 juin 2013 (in press)

Relecture à deux voix – historico-littéraire – des pièces du dossier épistolaire de Francfort attribué à Alcuin visant à dégager les stratégies littéraires et oratoires mises en œuvres par Alcuin au nom ... [more ▼]

Relecture à deux voix – historico-littéraire – des pièces du dossier épistolaire de Francfort attribué à Alcuin visant à dégager les stratégies littéraires et oratoires mises en œuvres par Alcuin au nom des évêques francs, d’une part, et de Charlemagne, de l’autre, pour tenter de ramener l’épiscopat espagnol dans le giron romain. Réflexion sur le rôle, l’importance et la puissance stylistique du genre épistolaire, hérité de l’Antiquité, dans deux foyers importants de haute culture de l’époque – la péninsule ibérique et le monde insulaire. [less ▲]

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See detailApprentissage collectif et réflexivité systémique: le rôle des aceurs tiers dans la structuration des méta-organisations
Xhauflair, Virginie ULg

in Interventions Economiques = Papers in Political Economy (in press)

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See detailScalar triplet flavored leptogenesis: a systematic approach
Aristizabal Sierra, Diego ULg; Dhen, Mikael; Hambye, Thomas

in Journal of Cosmology and Astroparticle Physics [= JCAP] (in press)

Type-II seesaw is a simple scenario in which Majorana neutrino masses are generated by the exchange of a heavy scalar electroweak triplet. When endowed with additional heavy fields, such as right-handed ... [more ▼]

Type-II seesaw is a simple scenario in which Majorana neutrino masses are generated by the exchange of a heavy scalar electroweak triplet. When endowed with additional heavy fields, such as right-handed neutrinos or extra triplets, it also provides a compelling framework for baryogenesis via leptogenesis. We derive in this context the full network of Boltzmann equations for studying leptogenesis in the flavored regime. To this end we determine the relations which hold among the chemical potentials of the various particle species in the thermal bath. This takes into account the standard model Yukawa interactions of both leptons and quarks as well as sphaleron processes which, depending on the temperature, may be classified as faster or slower than the Universe Hubble expansion. We find that when leptogenesis is enabled by the presence of an extra triplet, lepton flavor effects allow the production of the B-L asymmetry through lepton number conserving CP asymmetries. This scenario becomes dominant as soon as the triplets couple more to leptons than to standard model scalar doublets. In this case, the way the B-L asymmetry is created through flavor effects is novel: instead of invoking the effect of L-violating inverse decays faster than the Hubble rate, it involves the effect of L-violating inverse decays slower than the Hubble rate. We also analyze the more general situation where lepton number violating CP asymmetries are present and actively participate in the generation of the B-L asymmetry, pointing out that as long as L-violating triplet decays are still in thermal equilibrium when the triplet gauge scattering processes decouple, flavor effects can be striking, allowing to avoid all washout suppression effects from seesaw interactions. In this case the amount of B-L asymmetry produced is limited only by a universal gauge suppression effect, which nevertheless goes away for large triplet decay rates. [less ▲]

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See detailCodifying ‘Sacred Laws’ in Ancient Greece
Carbon, Jan-Mathieu ULg; Pirenne-Delforge, Vinciane ULg

in Jaillard, Dominique; Nihan, Christophe (Eds.) Legal Codification in Ancient Greece and Ancient Israel (in press)

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See detailPre-war Planning in Belgium
Bechet, Christophe ULg

in Janz, Oliver; Apostolopoulos, Nicolas (Eds.) 1914-1918-online. International Encyclopedia of the First World War (in press)

Abstract: Since the Treaty of London in 1839, pre-war planning theories in Belgium oscillated between two positions: on one hand secure and defend which border would be endangered, on the other hand ... [more ▼]

Abstract: Since the Treaty of London in 1839, pre-war planning theories in Belgium oscillated between two positions: on one hand secure and defend which border would be endangered, on the other hand constitute in Antwerp a powerful national sanctuary. This concentration of most of the available military means in Antwerp was far more appropriate in the event of a French invasion. But this perspective decreased after the Franco-Prussian war in 1870, while the possibility of a trespassing by the two belligerents became greater and greater. The fortifications of Namur and Liège were voted by the Chambers in 1887 as a deterrent to both France and Germany. Nevertheless, without totally putting aside the defence of the Belgian southwestern border, high-ranking officers seemed to fear more and more a violation of the eastern border. Due to the completion of fortifications on the Meuse in 1892, German columns were supposed to move forward south of the river, through the Belgian Ardennes. On the eve of the Great War, King Albert I would have preferred to concentrate the army on the Meuse but his Chief of Staff selected a central position in order to maintain and secure his line of communication with Antwerp. The lack of a determined and “standardized” doctrine at the highest level of the army led to a “mixed” or compromise plan adopted in a hurry during the first days of mobilization in August 1914. [less ▲]

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See detailA generic approach for solving nonlinear-discrete security-constrained power flow problems in large-scale systems
Platbrood, Ludovic; Capitanescu, Florin; Crisciu, Horia et al

in IEEE Transactions on Power Systems (in press)

This paper proves the practicality of an iterative algorithm for solving realistic large-scale SCOPF problems. This algorithm is based on the combination of a contingency filtering scheme, used to ... [more ▼]

This paper proves the practicality of an iterative algorithm for solving realistic large-scale SCOPF problems. This algorithm is based on the combination of a contingency filtering scheme, used to identify the binding contingencies at the optimum, and a network compression method, used to reduce the complexity of the post-contingency models included in the SCOPF formulation. We show that by combining these two complementary ideas, it is possible to solve in a reasonable time SCOPF problems on large power system models with a large number of contingencies. Unlike most results reported for large-scale SCOPF problems, our algorithm uses a non-linear AC network model in both pre-contingency and post-contingency states, optimizes both active/reactive powers flows jointly, and treats the discrete variables. The proposed algorithm is implemented with state-of-the-art solvers and applied to two systems: a national grid with 2563 buses and 1297 contingencies, and a model of the European transmission network with 9241 buses and 12000 contingencies. [less ▲]

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See detailLa fin du Paléolithique moyen dans le Nord de l’Europe : la question des origines du Lincombien-Ranisien-Jerzmanowicien
Flas, Damien ULg

in Depaepe, Pascal (Ed.) Les plaines du Nord-Ouest : carrefour de l’Europe au Paléolithique moyen ? (in press)

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See detailProteins in the gas phase
Meyer, Tim; Gabelica, Valérie ULg; Grubmüller, Helmut et al

in Wiley Interdisciplinary Reviews: Computational Molecular Science (in press)

Proteins are complex macromolecules that evolved over billions of years to be active in aqueous solution. Water is a key element that stabilizes their structure, and most structural studies on proteins ... [more ▼]

Proteins are complex macromolecules that evolved over billions of years to be active in aqueous solution. Water is a key element that stabilizes their structure, and most structural studies on proteins have thus been carried out in aqueous environment. However, recent experimental approaches have opened the possibility to gain structural information on proteins from gas-phase measurements. The obtained results revealed significant structural memory in proteins when transferred from water to the gas phase. However, after several years of experimental and theoretical research, the nature of the structural changes induced by vaporization, the exact characteristics of proteins in the gas phase, and the physicochemical forces stabilizing dehydrated proteins are still unclear. We will review here these issues using both experimental and theoretical sources of information. [less ▲]

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