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See detailVISMODEGIB ET CARCINOMES BASOCELLULAIRES LOCALEMENT AVANCES
LEBAS, Eglantine ULg; RORIVE, Andrée ULg; EL HAYDERI, Lara ULg et al

in Revue Médicale de Liège (2015)

Basal cell carcinoma is the most frequent skin cancer. Even though metastases are exceptional, these cancers may be locally highly aggressive. The Hedgehog signaling pathway plays a significant role in ... [more ▼]

Basal cell carcinoma is the most frequent skin cancer. Even though metastases are exceptional, these cancers may be locally highly aggressive. The Hedgehog signaling pathway plays a significant role in the pathogenesis of basal cell carcinoma. Vismodegib is a selective inhibitor of this pathway and may be administered orally. Its main indication is locally advanced basal cell carcinoma, when other therapeutic options have failed or are contra-indicated. Vismodegib can also be used as prophylactic therapy in the Gorlin syndrome or basal cell nevomatosis. Its principal adverse effects are muscle spasms, alopecia and altered taste. They are frequent, but often moderate in intensity; they sometimes restrict continuation of treatment. Two clinical cases are presented, relating the efficacity and tolerance of this new therapeutic option. [less ▲]

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See detailBeyond the Experience: Detection of Metamemorial Regularities
Geurten, Marie ULg; Willems, Sylvie ULg; Meulemans, Thierry ULg

in Consciousness & Cognition (2015), 33

We examined the mechanisms involved in the development of the easily learned, easily remembered (ELER) heuristic in three groups of young children (4–5 years, 6–7 years, and 8–9 years). A trial-to ... [more ▼]

We examined the mechanisms involved in the development of the easily learned, easily remembered (ELER) heuristic in three groups of young children (4–5 years, 6–7 years, and 8–9 years). A trial-to-acquisition procedure was used to evaluate how much these children’s judgment of learning depended on the ELER heuristic. Moreover, a new experimental paradigm, composed of six phases—a pretest, four training phases, and a posttest—was employed to implicitly influence the validity of the ELER association that underlies this metacognitive rule. Results revealed that the ELER heuristic develops early (4–5 years), but its use is reduced after implicit training. Furthermore, executive monitoring was found to account for the smaller changes observed in older children (8–9 years) after training. From a developmental perspective, these findings present a coherent picture of children’s learning of metacognitive heuristics, wherein early automatic and implicit learning is later followed by effortful control. [less ▲]

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See detailLegal mobilization in comparative perspective: workplace discrimination and access to domestic labor court in Sweden and Belgium
Lejeune, Aude ULg

Conference (2015)

Some scholarly works on legal mobilization have highlighted the diffusion of litigious policies to address social problems in Europe, considering that a rights’ revolution was underway. While many of ... [more ▼]

Some scholarly works on legal mobilization have highlighted the diffusion of litigious policies to address social problems in Europe, considering that a rights’ revolution was underway. While many of these studies have examined the diffusion of litigious policy at European level or in the United Kingdom, I suggest paying attention to Belgium and Sweden, two countries that have been under-examined by the socio-legal literature. Focusing on the implementation of anti- discrimination policy and norms, this paper explores the litigious activity of national equality agencies in the domestic labor court. The analysis of organizations’ litigious policy in Continental Europe invites to integrate another variable to the analysis of the structure of legal opportunities: the relationship between the State and interests groups. I suggest here that labor unions shape the access to labor courts by equality agencies in each national setting. This contribution aims to highlight equality agencies’ structure and agency within different labor contexts, current anti- discrimination policies and legal culture. It relies on open-ended interviews conducted with lawyers from equality agencies and labor unions in Belgium and Sweden. More broadly, this contribution examines the processes of policy implementation of European directive within member states. [less ▲]

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See detailFamilial Isolated pituitary adenomas (FIPA) and mutations in the aryl hydrocarbon receptor interacting protein (AIP) gene
Daly, Adrian ULg; Beckers, Albert ULg

in Endocrinology & Metabolism Clinics of North America (2015), 44

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See detailLa copie d’expression écrite en langue étrangère : un support équitable ?
Noiroux, Kevin ULg; Simons, Germain ULg

in Spirale (2015), 55

Summative writing assessment is an evaluative practice that aims, at least theoretically, to inform each student about his performance in that skill at a given time, and to help him to understand his ... [more ▼]

Summative writing assessment is an evaluative practice that aims, at least theoretically, to inform each student about his performance in that skill at a given time, and to help him to understand his errors so that he can make progress in his learning. In this article, we analyse summative writing assessment through various prisms. At the macro level, we discuss the reforms of the education system pertaining to assessment ; at the meso level, we target the assessment tools offered by the same education system, as well as the attention that may or may not be paid to remediation ; at the micro level, we deal with the issue of corrective feedback which students receive on their written production. By crossing these different sources (legal provisions, interviews, surveys, analysis of students’ annotated written production, etc.), we conclude that this practice may present major risks of inequality. [less ▲]

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See detailIdentiteiten, staatshervorming en stemgedrag
Deschouwer, Kris; De Winter, Lieven; Reuchamps, Min et al

in Deschouwer, Kris; Delwit, Pascal; Hooghe, Marc (Eds.) et al Het cryptogram van de kiezer. Het stemgedrag en de stemmotivaties op 25 mei 2014 (2015)

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See detailActive faulting at the western tip of the Gulf of Corinth, Greece, from high-resolution seismic data
Beckers, Arnaud ULg; Hubert, Aurelia ULg; Beck, Christian et al

in Marine Geology (2015)

The Gulf of Corinth is one of the fastest-spreading intra-continental rifts on Earth. GPS data indicate that the rift is currently opening in a NNE-SSW direction, with a rate of extension reaching up to ... [more ▼]

The Gulf of Corinth is one of the fastest-spreading intra-continental rifts on Earth. GPS data indicate that the rift is currently opening in a NNE-SSW direction, with a rate of extension reaching up to 16 mm yr-1 in its westernmost part. Although the rest of the offshore rift has been well studied, the western tip of the rift is still poorly explored. We present an accurate map of submarine faults in this area based on two high-resolution seismic reflection surveys (single channel sparker). In the eastern part of the studied area, the sedimentary infill is affected by the known North Eratini, South Eratini and West Channel faults. Further to the west, the seafloor is mostly flat, and is bounded to the north by the normal, south-dipping, Trizonia fault. To the north, the shallower part of the Gulf shows to the east a diffuse pattern of normal and strike-slip deformation which is replaced to the west by a 7.5 km long SE striking strike-slip fault zone, called the Managouli fault zone. To the westernmost tip of the Gulf, in the Nafpaktos Basin, two fault sets with different strikes are encountered; the one with aNE-SW strike exhibits a clear strike-slip component. The western tip of the Gulf of Corinth is the only part of the Corinth Rift where convincing evidence for strike-slip movement has been found. This fault pattern is likely related to the complex deformation occurring at the diffuse junction at the western tip of the Rift between three crustal blocks: Continental Greece, Peloponnese, and the Ionian Island-Akarnia block. [less ▲]

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See detailBoosting regulatory T-cell function with the humanized CD4-specific humanized monoclonal antibody Tregalizumab (BT-061)
Humblet-Baron, Stéphanie; Baron, Frédéric ULg

in Immunology & Cell Biology (2015), 1-2

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See detailOn the necessity and biological significance of threshold-free regulon prediction outputs
Rigali, Sébastien ULg; Nivelle, Renaud; Tocquin, Pierre ULg

in Molecular Biosystems (2015), 11

The in silico prediction of cis-acting elements in a genome is an efficient way to quickly obtain an overview of the biological processes controlled by a trans-acting factor, and connections between ... [more ▼]

The in silico prediction of cis-acting elements in a genome is an efficient way to quickly obtain an overview of the biological processes controlled by a trans-acting factor, and connections between regulatory networks. Several regulon prediction web tools are available, designed to identify DNA motifs predicted to be bound by transcription factors using position weight matrix-based algorithms. In this paper we expose and discuss the conflicting objectives of software creators (bioinformaticians) and software users (biologists), who aim for reliable and exhaustive prediction outputs, respectively. Software makers, concerned with providing tools that minimise the number of false positive hits, often impose a stringent threshold score for a sequence to be included in the list of the putative cis-acting sites. This rigidity eventually results in the identification of strongly reliable but largely straightforward sites, i.e. those associated with genes already anticipated to be targeted by the studied transcription factor. Importantly, this biased identification of strongly bound sequences contrasts with the biological reality where, in many circumstances, a weak DNA-protein interaction is required for the appropriate gene's expression. We show here a series of transcriptionally controlled systems involving weakly bound cis-acting elements that could never have been discovered because of the policy of preventing software users from modifying the screening parameters. Proposing only trustworthy prediction outputs thus prevents biologists from fully utilising their knowledge background and deciding to analyse statistically irrelevant hits that could nonetheless be potentially involved in subtle, unexpected, though essential cis-trans relationships. [less ▲]

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See detailLe regard (peu optimiste) du soignant sur la personne âgée
Schroyen, Sarah ULg; Missotten, Pierre ULg; Marquet, Manon ULg et al

in Medi-Sphere (2015)

L’âgisme (c’est-à-dire l’ensemble de nos stéréotypes liés à l’avancée en âge) a de nombreuses conséquences négatives tant pour le patient lui-même qu’au sein de la relation entre le patient et le ... [more ▼]

L’âgisme (c’est-à-dire l’ensemble de nos stéréotypes liés à l’avancée en âge) a de nombreuses conséquences négatives tant pour le patient lui-même qu’au sein de la relation entre le patient et le personnel soignant. Au cours de cet article, nous illustrerons les représentations du vieillissement prévalentes chez les soignants et aborderons brièvement les conséquences de l’âgisme sur leurs attitudes de soins. [less ▲]

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See detailEuropean Case-law on Asylum Matters: Interrelation and Interdependence of the European Court of Human Rights and the Court of Justice of the European Union
Mazur Kumric, Nives ULg; Župan, Mirela

in Sander, Gerald G.; Rodin, Siniša; Bodiroga-Vukobrat, Nada (Eds.) New Europe - Old Values?: Reform and Perseverance (Europeanization and Globalization) (2015)

The Council of Europe and the European Union (hereinafter: the EU) are major players and partners in the domain of policy shaping strategies on the European continent, with significant and evergrowing ... [more ▼]

The Council of Europe and the European Union (hereinafter: the EU) are major players and partners in the domain of policy shaping strategies on the European continent, with significant and evergrowing impact on international community as a whole. Although the ratio and ideas behind their establishment were not the same (economic versus humanistic), they have, over the time, acquired a similar attitude towards a number of legal issues, including protection of human rights and fundamental freedoms. Unlike the Council of Europe which perceived human rights as a cornerstone of its founding pillars, the EU took a longer way to incorporate them in its priority areas. The latter shift was, however, rapid and these days, one is witnessing a large-scale cooperation instituted between respective regional organisations with the aim of creating a human rights friendly environment. The purpose of this paper is to shed light on one particular segment of their cooperation in the field of human rights protection – asylum law. For the fact that Europe attracts a large contingency of people looking for better life and new beginnings, asylum matters have moved to the forefront of the Council of Europe and EU standard setting policies. The chapter following the introductory remarks gives an overview of the most crucial moments in the chronology of cooperation between the Council of Europe and the EU, observed from the angle of the Convention for the Protection of Human Rights and Fundamental Freedoms (hereinafter: the European Convention) and the related case-law of the two core European judicial organs: the European Court of Human Rights (hereinafter: the ECHR) and the Court of Justice of the European Union (hereinafter: the CJEU). A special emphasis is put on recent developments of historical significance related to the accession of the EU to the European Convention and peculiar legal consequences thereof. Chapter 3 focuses on the so-called Dublin system, a set of norms and mechanisms introduced to regulate a vast area of the asylum policy within the EU. The analysis keeps track with the steps taken in the creation of a common European asylum system, i.e. the three codification stages and their outcomes. Despite being of EU provenance, the respective system serves as a solid legal basis in asylum matters adjudicated by both European courts. Finally, the chapter preceding the conclusion highlights some of the leading asylum cases which demonstrate a close interrelation and interdependance of the European courts and their case-law in the area of European asylum policies. The sub-chapter on the ECHR case-law summarises the most notable facts, elements and standards derived from the judgments in the cases of M. S. S. v. Belgium and Greece, T. I. v. the United Kingdom and K. R. S. v. the United Kingdom, as well as Mohammed Hussein and Others v. the Netherlands and Italy, and Mohammed v. Austria. In the same vein, the CJEU case-law is elaborated in another sub-chapter; namely, the authors draw attention to the cases of N. S. v. Secretary of State for the Home Department and M. E. and others v. Refugee Applications Commissioner, Minister for Justice, Equality and Law Reform; Meki Elgafaji, Noor Elgafaji v. Staatssecretaris van Justitie; and Shamso Abdullahi v. Bundesasylamt. The purpose of this case-law overview and analysis is to sum up major rules, theories and standards originating from the judgements, as well as to find the points of convergence and differentiation between the ECHR and the CJEU in asylum matters. [less ▲]

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See detailObservations sur la forme, l'état du support et la mise en page du P.Vat.gr. 11
Carlig, Nathan ULg

in Amato, Eugenio; Marganne, Marie-Hélène (Eds.) Le traité "Sur l'exil" de Favorinos d'Arles. Papyrologie, philologie et littérature (2015)

Observations sur le papyrus de Favorinos, son état de conservation et ses caractéristiques de forme et de mise en page, effectuées après autopsie du rouleau à la Biblioteca Apostolica Vaticana

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See detailCharles Travis, La vision est-elle intentionnelle ?
Ambroise, Bruno; Gauvry, Charlotte ULg

in Dewalque, Arnaud; Gauvry, Charlotte (Eds.) Conscience et représentation. Controverses récentes en philosophie de l'esprit (2015)

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See detailCharles Travis, Déverrouiller le monde extérieur
Gauvry, Charlotte ULg

in Gauvry, Charlotte; Brisart, Robert (Eds.) Concept et perception. Le conceptualisme en question (2015)

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See detailHeidegger : « Être et temps », « Introduction à la métaphysique », « Qu’appelle-t-on penser ? », « Acheminement vers la parole »
Gauvry, Charlotte ULg

in Suratteau, Jean-François (Ed.) Dictionnaire des œuvres philosophiques (2015)

Articles de dictionnaire

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See detailIntroduction
Gauvry, Charlotte ULg

in Dewalque, Arnaud; Gauvry, Charlotte (Eds.) Conscience et représentation. Controverses récentes en philosophie de l'esprit (2015)

Introduction au volume

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See detailGadamer, Vérité et méthode
Gauvry, Charlotte ULg

in Suratteau, Jean-François (Ed.) Dictionnaire des œuvres philosophiques (2015)

article de dictionnaire

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See detailIntroduction
Gauvry, Charlotte ULg

in Brisart, Robert; Gauvry, Charlotte (Eds.) Concept et perception. Le conceptualisme en question (2015)

Introduction au volume

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See detailAcoustic monitoring of O2 production of a seagrass meadow
Felisberto, Paulo; Jesus, Sérgio M.; Zabel, Friedrich et al

in Journal of Experimental Marine Biology and Ecology (2015), 464(0), 75-87

Acoustic data were acquired in October 2011 over a Posidonia oceanica meadow in the Bay of la Revellata, Calvi, Corsica. The purpose was to develop an acoustic system for monitoring the oxygen (O2 ... [more ▼]

Acoustic data were acquired in October 2011 over a Posidonia oceanica meadow in the Bay of la Revellata, Calvi, Corsica. The purpose was to develop an acoustic system for monitoring the oxygen (O2) production of an entire seagrass meadow. In a shallow water area (b38 m), densely covered by P. oceanica, a sound source transmitted signals in 3 different bands (400–800 Hz, 1.5–3.5 kHz and 6.5–8.5 kHz) toward three self-recording hydrophones at a distance of 100 m, over the period of oneweek. The data showa high correlation between the diel cycle of the acoustic signals' energy received by the hydrophones and the temporal changes in water column O2 concentration as measured by optodes. The results thus show that a simple acoustic acquisition system can be used to monitor the O2-based productivity of a seagrass meadow at the ecosystem level with high temporal resolution. The finding of a significant production of O2 as bubbles in seagrass ecosystems suggests that net primary production is underestimated by methods that rely on the mass balance of dissolved O2 measurements. [less ▲]

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