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See detailCompact handheld low-cost biosensor platform for remote health monitoring
Hastanin, Juriy ULg; Lenaerts, Cedric ULg; Gailly, Patrick ULg et al

in Proceedings of SPIE; SPIE 2016 Photonics Europe (2016, April)

In this paper, we present an original concept of plasmonic-related instrumentation platform dedicated to diagnostic biosensing tests out of the laboratory. The developed instrumental platform includes ... [more ▼]

In this paper, we present an original concept of plasmonic-related instrumentation platform dedicated to diagnostic biosensing tests out of the laboratory. The developed instrumental platform includes both disposable one-use microfluidic affinity biochip and compact optical readout device for biochip monitoring involving mobile Internet devices for data processing and communication. The biochip includes both microfluidic and optical coupling structures formed into a single plastic slab. The microfluidic path of the biochip operates in passive capillary pumping mode. In the proof-of-concept prototype, we address specifically the sensing format involving Surface Plasmon Resonance phenomenon. The biochip is plugged in the readout device without the use of an index matching fluid. An essential advantage of the developed biochip is that its implementation involves conventional hot embossing and thin film deposition process, perfectly suited for mass production of low-cost microfluidic biochip for biochemical applications. [less ▲]

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See detailDesign optimization of large-size format edge-lit light guide units
Hastanin, Juriy ULg; Lenaerts, Cedric ULg; Fleury-Frenette, Karl ULg

in Proceedings of SPIE; SPIE 2016 Photonics Europe (2016, April)

In this paper, we present an original method of dot-pattern generation dedicated to design optimization of large-size format ELBUs (Edge-Lit Light Guide Unit), where the number of dots greatly exceeds the ... [more ▼]

In this paper, we present an original method of dot-pattern generation dedicated to design optimization of large-size format ELBUs (Edge-Lit Light Guide Unit), where the number of dots greatly exceeds the maximum allowable number of optical objects supported by most common ray-tracing software. In the proposed method, in order to simplify the computational problem, an original optical system is replaced by an equivalent one. Accordingly, the original dot pattern is splitted into multiple small sections. Then, these sections are replaced by equivalent cells with continuous diffusing film. After that, we adjust the TIS (Total Integrated Scatter) two-dimensional distribution over the grid of equivalent cells, using an iterative optimization procedure. Finally, the obtained optimal TIS distribution is converted into the dot size distribution by applying an appropriate conversion rule. An original semi-empirical equation dedicated to rectangular large-size LGPs (Light Guide Plate) is proposed for the initial guess of the TIS distribution. It allows significantly reducing the time needed to dot pattern optimization. [less ▲]

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See detailDer Archäotraduktosaurus blickt zurück
Viehöver, Vera ULg

in ReLü: Rezensionszeitschrift zur Literaturübersetzung (2016)

Der Archäotraduktosaurus blickt zurück Vera Viehöver über Sourcier ou cibliste von Jean-René Ladmiral Jean-René Ladmiral, der sich selbst als „letzten Überlebenden eines längst vergangenen, vordigitalen ... [more ▼]

Der Archäotraduktosaurus blickt zurück Vera Viehöver über Sourcier ou cibliste von Jean-René Ladmiral Jean-René Ladmiral, der sich selbst als „letzten Überlebenden eines längst vergangenen, vordigitalen Erdzeitalters der Übersetzung“ sieht, gehört zu den Gründungsvätern der institutionalisierten Übersetzungswissenschaft in Frankreich. Der Band Sourcier ou cibliste (2014) versammelt Beiträge des Autors aus mehr als drei Jahrzehnten, die bislang zum Teil nur schwer auffindbar waren: die Bilanz eines leidenschaftlichen Kämpfers, der ein Übersetzen für die Leser fordert – scharf im Urteil gegen die Sakralisierung und Fetischisierung von literarischen Texten. [less ▲]

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See detailContribution à l'optimisation technico-économique des élevages laitiers en Wallonie : l'intervalle vêlage
Dalcq, Anne-Catherine ULg; Beckers, Yves ULg; Dogot, Thomas ULg et al

Conference given outside the academic context (2016)

Au cours des dernières décennies, l’intervalle vêlage des vaches laitières a eu tendance à s’allonger au niveau mondial, européen et belge. Les causes sont multiples : évolution du système de production ... [more ▼]

Au cours des dernières décennies, l’intervalle vêlage des vaches laitières a eu tendance à s’allonger au niveau mondial, européen et belge. Les causes sont multiples : évolution du système de production laitière, augmentation du niveau de production,… Les conséquences sont nombreuses également mais se traduisent-elles par un impact économique pour l’éleveur laitier ? La recherche présentée aujourd’hui se base sur près de 1800 bilans comptables de 400 exploitations laitières, fournis par le service technico-économique de l’Association Wallonne de l’Elevage, entre 2007 et 2014, pour déterminer l’impact économique de la durée de l’intervalle vêlage et définir l’optimum technico-économique de ce paramètre de management. Faut-il garder en tête « le veau par vache et par an » ou est-il intéressant économiquement d’allonger la période entre deux vêlages pour une même vache ? L’étude révèle qu’il y a bien une relation entre l’intervalle vêlage et les résultats économiques d’une exploitation. De plus, il n’y aurait pas un seul optimum d’intervalle vêlage mais plusieurs, dépendant du type d’exploitation et plus particulièrement du mode d’alimentation. L’optimum de l’intervalle vêlage a tendance à être plus court pour les exploitations à alimentation plutôt intensive et plus long pour les exploitations à alimentation plutôt extensive. Cependant il ne s’agit que de tendances observées, un travail plus approfondi doit encore être réalisé pour confirmer ces tendances et définir des objectifs plus précis à poursuivre pour maximiser la rentabilité de son exploitation. [less ▲]

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See detailCharacterization of monovarietal virgin olive oils from introduced cultivars in eastern Morocco
Mansouri, Farid ULg; Benmoumen, A.; Richard, Gaetan ULg et al

in Rivista Italiana Sostanze Grasse (2016), 93

The aim of this study was to characterize monovarietal virgin olive oils (VOOs) of new high-density planting system of three European cultivars (Arbequina, Arbosana and Koroneiki), recently introduced in ... [more ▼]

The aim of this study was to characterize monovarietal virgin olive oils (VOOs) of new high-density planting system of three European cultivars (Arbequina, Arbosana and Koroneiki), recently introduced in eastern Morocco. VOOs’ characterization has been carried out by analyzing several parameters, such as quality indexes, fatty acid contents, minor components, and olive oils’ oxidative stability index (OSI). In this study, we have also conducted a comparison between these monovarietal VOOs and olive oils of autochthones cultivar Picholine marocaine. Significant differences between the analyzed VOOs were highlighted. Koroneiki’s VOO had a high phenols content (493.66 mg/kg) and, consequently, the best oxidative stability (94.83 h); Arbrosana’s VOO was distinguished by its abundance of α-tocopherol (460.07 mg/kg) and by an intermediate OSI (64.83 h). In addition, results showed, firstly, that in all the analyzed oils decarboxymethyl ligstroside aglycone and decarboxymethyl oleuropein aglycone were the main phenolic compounds, and, secondly, that VOOs of Koroneiki and Arbosana seem to have similar profiles, with a high content of natural antioxidants and a high oleic/linoleic ratio, thus boasting a better shelf life. [less ▲]

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See detailLe législateur wallon sommé de revoir le découpage des circonscriptions électorales
Bouhon, Frédéric ULg

E-print/Working paper (2016)

Le caractère proportionnel de notre système électoral n’est pas un vain mot et ne peut être contourné. C’est ce que viennent de rappeler deux arrêts, le premier, prononcé par le Conseil d’État, datant du ... [more ▼]

Le caractère proportionnel de notre système électoral n’est pas un vain mot et ne peut être contourné. C’est ce que viennent de rappeler deux arrêts, le premier, prononcé par le Conseil d’État, datant du 20 novembre 2014 (n° 229.252) , le second, rendu par la Cour constitutionnelle le 26 novembre 2015 (n° 169/2015) . Le Parlement wallon doit revoir la carte électorale en vue des prochaines élections. [less ▲]

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See detailMusiciens et musiciennes à Mari (tell Hariri, Syrie) durant la fin de l’époque des shakkanakkus.
Colonna d'Istria, Laurent ULg

Scientific conference (2016, March 31)

Les sources écrites de la fin de l’époque des shakkanakkus (19e siècle av. J.-C.) sont en grande majorité des bordereaux administratifs découverts sur le site de Mari (Tell Hariri, Syrie). Ces quelques ... [more ▼]

Les sources écrites de la fin de l’époque des shakkanakkus (19e siècle av. J.-C.) sont en grande majorité des bordereaux administratifs découverts sur le site de Mari (Tell Hariri, Syrie). Ces quelques 2000 documents nous renseignent sur divers aspects de l’administration palatiale à cette époque, et citent à plusieurs reprises des musiciens et musiciennes. Appartenant au personnel du palais, ces musicien(ne)s recevaient des rations alimentaires et divers biens dont certains relatifs à leur fonction. Par ailleurs, étant responsables de transactions administratives, ces individus participaient activement à la gestion des biens du palais. Enfin, à l’instar de militaires ou de scribes, des musiciens font fonction d’intermédiaires dans la livraison de biens précieux offerts à différentes personnes appartenant à des élites, en particulier des seigneurs tribaux amorrites. [less ▲]

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See detailDiurnal cycle and multi-decadal trend of formaldehyde in the remote atmosphere near 46° N
Franco, Bruno ULg; Marais, Eloise A.; Bovy, Benoît ULg et al

in Atmospheric Chemistry and Physics (2016), 16

Only very few long-term records of formaldehyde (HCHO) exist that are suitable for trend analysis. Furthermore, many uncertainties remain as to its diurnal cycle, representing a large short-term ... [more ▼]

Only very few long-term records of formaldehyde (HCHO) exist that are suitable for trend analysis. Furthermore, many uncertainties remain as to its diurnal cycle, representing a large short-term variability superimposed on seasonal and inter-annual variations that should be accounted for when comparing ground-based observations to e.g., model results. In this study, we derive a multi-decadal time series (January 1988 – June 2015) of HCHO total columns from ground-based high-resolution Fourier transform infrared (FTIR) solar spectra recorded at the high-altitude station of Jungfraujoch (Swiss Alps, 46.5° N, 8.0° E, 3580 m a.s.l.), allowing for the characterization of the mid-latitudinal atmosphere for background conditions. First we investigate the HCHO diurnal variation, peaking around noontime and mainly driven by the intra-day insolation modulation and methane (CH4) oxidation. We also characterize quantitatively the diurnal cycles by adjusting a parametric model to the observations, which links the daytime to the HCHO columns according to the monthly intra-day regimes. It is then employed to scale all the individual FTIR measurements on a given daytime in order to remove the effect of the intra-day modulation for improving the trend determination and the comparison with HCHO columns simulated by the state-of-the-art chemical transport model GEOS-Chem v9-02. Such a parametric model will be useful to scale the Jungfraujoch HCHO columns on satellite overpass times in the framework of future calibration/validation efforts of space borne sensors. GEOS-Chem sensitivity tests suggest then that the seasonal and inter-annual HCHO column variations above Jungfraujoch are predominantly led by the atmospheric CH4 oxidation, with a maximum contribution of 25 % from the anthropogenic non-methane volatile organic compound precursors during wintertime. Finally, trend analysis of the so-scaled 27-year FTIR time series reveals a long-term evolution of the HCHO columns in the remote troposphere to be related with the atmospheric CH4 fluctuations and the short-term OH variability: +2.9 %/yr between 1988 and 1995, -3.7 %/yr over 1996-2002 and +0.8/% yr from 2003 onwards. [less ▲]

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See detailDimensioning IRGA gas sampling systems: laboratory and field experiments
Aubinet, Marc ULg; Joly, Lilian; Loustau, Denis et al

in Atmospheric Measurement Techniques (2016), 9

Both laboratory and field experiments were carried out in order to define suitable configuration ranges for the gas sampling systems (GSSs) of infrared gas analyzers (IRGAs) used in eddy covariance ... [more ▼]

Both laboratory and field experiments were carried out in order to define suitable configuration ranges for the gas sampling systems (GSSs) of infrared gas analyzers (IRGAs) used in eddy covariance measurements. In the laboratory, an original dynamic calibration bench was developed in order to test the frequency attenuation and pressure drop generated by filters. In the field, three IRGAs of the same type equipped with different filters or different rain caps were installed and run and the real frequency response of the complete setup was tested. The main results are as follows. – Filters may have a strong impact on the pressure drop in the GSS and this impact increases with flow rate. – Conversely, no impact of the tested filters on cut-off frequency was found, GSSs with and without filters presenting similar cut-off frequencies. – The main limiting factor of cut-off frequency in the field was found to be the rain cap design. In addition, the impact of this design on pressure drop was also found to be noteworthy. [less ▲]

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See detailAbout Quaternary prevention in Public health ; comment on Dr Jong-Myon Bae paper
Jamoulle, Marc ULg

in Journal of Preventive Medicine and Public Health = Yebang Uihakhoe Chi (2016), 49(2), 139-140

The recent paper of Dr Jong-Myon Bae about Quaternary Prevention and Public Health in your journal has attracted my interest. The spread of this concept is beyond all expectation and I am quite happy it ... [more ▼]

The recent paper of Dr Jong-Myon Bae about Quaternary Prevention and Public Health in your journal has attracted my interest. The spread of this concept is beyond all expectation and I am quite happy it contributes to the analytic thinking of complexity of health care. The particular application of the quaternary prevention (P4) concept is absolutely brilliant. Nevertheless I would propose some slight modifications to the table 1 edited by the author which I have taken the liberty to reproduce here with the due authorization of Dr Bae and after several mail exchanges with him. [less ▲]

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See detailGembloux veut sauver les oliviers
Jijakli, Haissam ULg

Article for general public (2016)

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See detailUne solution belge pour sauver les oliviers du sud de l'Italie?
Jijakli, Haissam ULg

Article for general public (2016)

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See detailImpacts of Ionizing Radiation on the Different Compartments of the Tumor Microenvironment
Leroi, Natacha ULg; LALLEMAND, François ULg; COUCKE, Philippe ULg et al

in Frontiers in Pharmacology (2016), 7

During the last decade, the initial cancer cell-centered view of tumors has greatly evolved to an integrated vision of tumor biology taking into account the key contribution of the TME. Obviously, the ... [more ▼]

During the last decade, the initial cancer cell-centered view of tumors has greatly evolved to an integrated vision of tumor biology taking into account the key contribution of the TME. Obviously, the different compartments of TME are closely related and contribute not only to tumor progression, but also to its response to treatments. Importantly, the TME evolves over time during the different steps of cancer development and is also affected by different therapeutic modalities. Although, improvements have been achieved regarding RT delivery to the primary tumor, ionizing radiation also target nontumor cells that influence tumor growth and metastatic dissemination. Different approaches have been proposed to overcome the radioresistance of cancer cells. The TME-mediated radioresistance is now the object of researches, which has been elegantly reviewed recently by Barker et al. (2015) and severalarticles pointed out the importance of treatments that modify the TME and likely radiosensitize tumor (Ansiaux et al., 2005; Crokart et al., 2005b; Frérart et al., 2008). However, the impact of anti-cancer treatments on the TME and consequently on the tumor phenotype, response to treatment and metastases, is often neglected. Here we pointed out the impact of RT on the TME. Recent findings emphasize the interest to optimize RT (i.e., dose per fraction) and timing of surgery (Leroi et al., 2015; Surace et al., 2015) in order to prevent metastatic spreading. The future challenge in RT will be to define the most appropriate combinations between RT, and other therapeutic modalities with the optimal sequence and timing of treatments. In this context, investigation of the TME-related acquired resistance will be essential and will provide important innovative data. [less ▲]

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See detailValeurs de l'information et performances algorithmiques pour des problèmes multi-périodes et stochastiques
Pironet, Thierry ULg

Scientific conference (2016, March 30)

voir document

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See detailRevealing the role of network rigidity on the fragility evolution of glass-forming liquids
Yildirim, Can ULg; Raty, Jean-Yves ULg; Micoulaut, Mathieu

E-print/Working paper (2016)

If quenched fast enough, a liquid is able to avoid crystallization and will remain in a metastable supercooled state down to the glass transition, with an important increase in viscosity and relaxation ... [more ▼]

If quenched fast enough, a liquid is able to avoid crystallization and will remain in a metastable supercooled state down to the glass transition, with an important increase in viscosity and relaxation time towards equilibrium upon further cooling [1,2]. There are important differences in the way liquids relax as they approach the glass transition, rapid or slow variation in dynamic quantities under moderate temperature changes, and a simple means to quantify such variations is provided by the concept of "fragility". Here, we report molecular dynamics simulations of a typical network-forming glass, and find that the relaxation behaviour of the supercooled liquid is strongly correlated to the variation of rigidity with temperature and the spatial distribution of the corresponding topological constraints which, ultimately connect to fragility minima . This permits extending the fragility concept to aspects of topology/rigidity, and to the degree of homogeneity of the atomic-sale interactions for a variety of structural glasses. [less ▲]

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See detailhCG: false positives and persistent hCG levels
VALDES SOCIN, Hernan Gonzalo ULg

Scientific conference (2016, March 29)

Human Chorionic gonadotropin (hCG) is a complex glycoprotein with several bioactive forms. These five variants comprise placental forms (hyperglycosilated hCG is the first form, then after 10 weeks of ... [more ▼]

Human Chorionic gonadotropin (hCG) is a complex glycoprotein with several bioactive forms. These five variants comprise placental forms (hyperglycosilated hCG is the first form, then after 10 weeks of pregnancy total hCG takes over), cancer promoter forms (hCGb, hyperglycosilated hCGb), and a pituitary form (sulfated hCG). Current routine laboratory tests do not discriminate between these multiple variants of hCG. Low persistent detectable levels of hCG may be associated with various benign and malignant conditions, such as quiescent gestational trophoblastic disease, raised pituitary hCG, or false positive elevation caused by circulating heterophilic antibodies. Clinico-biological discussion are mandatory to avoid erroneous diagnosis and treatment.In this review we summarize and discuss the different causes of false positive hCG assay. We suggest that current gynecological protocols for the diagnosis and treatment of trophoblastic disease should consider the inclusion of hCG test in urine and/or a test for heterophilic antibodies, when appropriate to avoid unnecessary studies and treatment. References. Valdes Socin H, Syrios P, Gadisseur R, et al. Persistent low levels of hCG: please do not miss phantom hCG! (pseudohypergonadotropinemia syndrome). Acta Clinica Belgica (abstract) 2013;68:465. Cole LA. hCG, the wonder of today’s science. Reprod Biol Endocrinol 2012;10:24–42. B. González Aguilera, P. Syrios, R. Gadisseur, F. Luyckx, E. Cavalier, A. Beckers & H. Valdes-Socin. Persistent low levels of serum hCG due to heterophilic mouse antibodies: an unrecognized pitfall in the diagnosis of trophoblastic disease . Gynecological Endocrinology 2016. DOI:10.3109/09513590.2015.1132303 [less ▲]

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See detailEspace, temps et angoisse psychotique : à propos d'un cas magistral
Englebert, Jérôme ULg

Scientific conference (2016, March 26)

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See detailInfluence of extraction conditions on characteristics of microbial polysaccharide kefiran isolated from kefir grains biomass
Pop Rodica, Carmen; Salanţă, Liana; M. Rotar, Ancuţa et al

in Journal of Food and Nutrition Research (2016)

Kefiran is a water-soluble polysaccharide, which can be isolated from kefir grains biomass. Rheological behaviour and physico-chemical characteristics of kefiran solutions were influenced by the ... [more ▼]

Kefiran is a water-soluble polysaccharide, which can be isolated from kefir grains biomass. Rheological behaviour and physico-chemical characteristics of kefiran solutions were influenced by the extraction parameters. Degradation of the polymer chain occurred at the highest temperature tested (100 °C). The intrinsic viscosity of kefiran solutions (0.1 g·ml-1) varied between 8.24 mPa at 100 °C to 19.32 mPa at 80 °C. Regarding rheological properties, kefiran solutions had characteristics of a Newtonian behaviour in diluted solutions and pseudoplastic at higher concentrations. High-performance liquid chromatography analysis of monosaccharides revealed that kefiran is composed of glucose and galactose in a relative molar ratio of 0.94–1.1. Infrared spectra of kefiran suggested the structure of α- and β-configurations in pyranose-form carbohydrates, which indicated a purified structure of kefiran. The molecular weight of kefiran polymer was between 2.4 × 106 Da and 1.5 × 107 Da, the values of molecular weight depending on extraction conditions. This polysaccharide was found to have higher intrinsic viscosity and higher apparent viscosity in aqueous solutions, which brings a perspective for its use as thickening or gelling agent in food, or as a matrix in film-forming solutions. [less ▲]

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