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See detailDo nonbelieved memories typically refer to childhood memories?
Vanootighem, Valentine ULg; Brédart, Serge ULg

Conference (2017, May 31)

Detailed reference viewed: 18 (3 ULg)
See detailLe "Good Lives Model", un modèle novateur d'intervention au service des besoins de l'usager: Expérience d'adaptation au sein de l'hôpital psychiatrique sécurisé "Les Marronniers" à Tournai
Henrard, Noémie ULg; Devillers, Bérengère ULg; Oswald, Pierre et al

Conference (2017, May 31)

L’Hôpital Psychiatrique Sécurisé (H.P.S.) « Les Marronniers » de Tournai fut la première équipe francophone, en collaboration avec le Groupe Antigone, à avoir adapté le Good Lives Model (GLM) à une ... [more ▼]

L’Hôpital Psychiatrique Sécurisé (H.P.S.) « Les Marronniers » de Tournai fut la première équipe francophone, en collaboration avec le Groupe Antigone, à avoir adapté le Good Lives Model (GLM) à une population psychiatrique (GLM – FM). Le cadre théorique et méthodologique du G.L.M – FM offre la possibilité de dépasser le paradigme du risque/rechute en proposant des principes et outils qui guident l’intervention tout en tenant compte du rôle des symptômes psychiatriques/infraction et des besoins humains fondamentaux de l’usager. Le G.L.M – FM implique d’élaborer avec l’usager un « Good Live Plan », plan de vie visant à satisfaire les besoins humains fondamentaux et à accéder à une meilleure qualité de vie. Le G.L.M- FM intègre à la fois les risques et les perspectives de réadaptation, et ce, dans une approche globale, intégrée et cohérente. Objectifs : - Présenter les fondements théoriques et les principes cliniques de base qui guident le Good Lives Model - Forensic Mental Health ; - Présenter différents outils cliniques (général et spécifique) permettant l’opérationnalisation du GLM-FM ; - Développer l’expérimentation et l’adaptation du G.L.M. réalisé au sein de l’H.P.S. de Tournai au travers des projets UET et Epicéas. Méthodes d’apprentissage : - Expérimentation par les participants d’un des champs de l’outil de l’Inventaire des Souhaits et Préoccupations Personnels (ISPP) ; - Articulation des principes théoriques et cliniques ; [less ▲]

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Peer Reviewed
See detailRecognition memory is associated with hippocampal volume in aging population: new evidence from brain imaging study
Narbutas, Justinas ULg; Blanpain, Manon ULg; Van Egroo, Maxime ULg et al

Poster (2017, May 31)

Introduction. The hippocampus is crucial for episodic memory, especially for recollection and pattern separation (i.e., the ability to store similar episodes as distinct memory traces). Episodic memory ... [more ▼]

Introduction. The hippocampus is crucial for episodic memory, especially for recollection and pattern separation (i.e., the ability to store similar episodes as distinct memory traces). Episodic memory declines with aging and this has been associated with hippocampal dysfunction. The main objective of our study was to explore how performance on a recognition memory task designed to assess pattern separation is associated with hippocampal volume in aging population. Method. Fourteen healthy late middle-aged participants (52-69 years-old) were evaluated on a Mnemonic Similarity Task (MST). In this task, participants study pictures and then have to discriminate between targets, similar lures, and unrelated foil objects. Recognition memory (RM) is assessed as the difference between hits and false alarms to unrelated foils, while pattern separation Bias metric (BPS) is the difference between the rate of ‘‘Similar’’ responses given to the lure items minus ‘‘Similar’’ responses given to the foils. Hippocampal volume was calculated using ASHS software, which uses T1-weighted and T2-weighted MRI to obtain optimal segmentation of hippocampal subfields. Results. Correlation analysis of preliminary data revealed that RM was significantly positively associated with the volume of the left subiculum and left perirhinal area 35. BPS was positively correlated with the volume of right CA2 region, but negatively associated with the volume of right CA3 region. Discussion. In a late middle-aged population, better visual recognition memory is associated with larger volume of the left subiculum and perirhinal area 35, two regions supporting representation of objects. [less ▲]

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See detailÉvaluation des impacts des ouvrages transversaux sur le transport sédimentaire et l’hydromorphologie
Peeters, Alexandre ULg; Petit, François ULg; Houbrechts, Geoffrey ULg

Conference (2017, May 31)

Le transport naturel des sédiments de la charge de fond est aujourd'hui clairement identifié comme un contributeur essentiel pour atteindre le bon état écologique des cours d’eau (Directive 2000/60/CE ... [more ▼]

Le transport naturel des sédiments de la charge de fond est aujourd'hui clairement identifié comme un contributeur essentiel pour atteindre le bon état écologique des cours d’eau (Directive 2000/60/CE). Lorsque le transport sédimentaire est entravé par des obstacles, l’équilibre hydromorphologique et écologique de la rivière est alors perturbé. Ces obstacles à la continuité écologique sont nombreux dans le bassin versant du Bocq (233 km², affluent de la Meuse en Wallonie) : on en dénombre 76 sur les 135 km de linéaire de cours d'eau, ce qui représente 1 obstacle tous les 1,8 km en moyenne. Il s'agit principalement d'ouvrages transversaux liés à des usages anciens du cours d’eau (moulin, forge, abissage, pompe à eau, etc.). Dans le cadre du projet UE LIFE+ Walphy, des travaux de réhabilitation de la continuité écologique ont été réalisés entre 2009 et 2013 sur 22 ouvrages transversaux du bassin du Bocq. Avant la réalisation des travaux, plusieurs ouvrages ont fait l’objet d’un diagnostic hydromorphologique et sédimentaire, basé sur l'identification des zones impactées (remous liquide et solide) d'une part, et l'évaluation de l'effet de piégeage de l'ouvrage d'autre part. Ce dernier point repose sur la caractérisation de l'ouvrage et du remplissage de sa retenue, ainsi que sur des mesures granulométriques et des marquages de la charge de fond (transpondeurs passifs). Ainsi, nous avons mis en évidence différents cas de piégeage de la charge de fond : absent, partiel ou total. Parmi les travaux de réhabilitation de la continuité écologique, ce sont les projets de suppression d'obstacle qui sont les plus efficaces, comme l'illustre le cas du déversoir de Spontin, pour lequel nous avons quantifié les impacts de son arasement des points de vue hydromorphologique et sédimentaire. Enfin, l’aménagement d'une rampe rugueuse sur un site fortement artificialisé (lit bétonné) à contrainte importante (protection de captages d'eau potable) constitue un cas particulier de réhabilitation de la continuité écologique, pour lequel l'analyse approfondie du transport sédimentaire a fourni les éléments nécessaires au bon dimensionnement des matériaux à utiliser. [less ▲]

Detailed reference viewed: 77 (3 ULg)
Peer Reviewed
See detailStranger harassment: perception, tolerance and the influence of gender identities and gender stereotypes
Goblet, Margot ULg; Glowacz, Fabienne ULg

Poster (2017, May 31)

Stranger harassment is defined as gender based harassment in public spaces. Despite its frequency and its detrimental consequences, research has barely begun to address this phenomenon. Stranger ... [more ▼]

Stranger harassment is defined as gender based harassment in public spaces. Despite its frequency and its detrimental consequences, research has barely begun to address this phenomenon. Stranger harassment is in the eye of the beholder. Gender differences and contextual factors are decisive for its interpretation (Fairchild, 2010; Rotundo, Nguyen and Sackett, 2001). The aim of this study is to estimate contextual factors of stranger harassment and more precisely to examine the influence of gender identities and gender roles on perception and tolerance of stranger harassment within a population of young women and men aged 18-35. Two methods of data collection are used, a paper questionnaire and an on-line questionnaire. The sample should include more than 600 subjects. Participants are surveyed regarding their global life satisfaction (Satisfaction With Life Scale, Diener et al., 1985), personal experiences of stranger harassment (Sexual Experience Questionnaire, Fairchild, 2010) and the context of occurrence and the consequences of those experiences on several aspects of their life. Acceptation and tolerance of sexual harassment (Sexual Harassment Attitude Scale, Mazer et Percival, 1989), identification to gender roles (short French version of Bem Sex-Roles Inventory, Fontayne et al., 2000) and experiences of sexual victimization are also addressed. Results will provide us an overview of stranger harassment and its occurrence. Some risk factors may be identified, as experiences of sexual victimization that may influence tolerance of stranger harassment. Furthermore, the influence of gender roles and gender identities may be crucial for the understanding of stranger harassment as a gender based behavior [less ▲]

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See detailFemmes auteures d’infraction à caractère sexuel en guidance sous contrainte judiciaire : entre représentations et réalités ?
Glowacz, Fabienne ULg; Lagneaux, Julien; MALEMPRE, Marc et al

Poster (2017, May 31)

La délinquance a été le plus souvent conjuguée au masculin alors que la violence des femmes est restée longtemps ignorée. Il en est de même pour la délinquance sexuelle agie par les femmes qui est étudiée ... [more ▼]

La délinquance a été le plus souvent conjuguée au masculin alors que la violence des femmes est restée longtemps ignorée. Il en est de même pour la délinquance sexuelle agie par les femmes qui est étudiée depuis peu et est reconnue tout en étant encore méconnue. Notre étude porte sur l’analyse de 23 dossiers émanant de 4 centres de santé mentale spécialisés en Belgique qui ont notamment pour mission de dresser des avis motivés à la demande d’autorité mandante dans le cadre d’un sursis probatoire, d’une libération probatoire ou définitive. L’analyse de contenu des dossiers a permis d’identifier les caractéristiques psychologique, sociale, sexuelle et criminologique des sujets ainsi que la nature des infractions commises et le profil de victimes. Dans la lignée des travaux en matière de délinquance non sexuelle, nous avons repris plusieurs questions dont celles du statut de la femme en tant que auteure et co-auteure, de la présence de troubles psychopathologiques, de l’usage de violences physiques, des antécédents judiciaires ainsi que des dynamiques familiales dans lesquelles elles ont évolué. Plus spécifiquement à la délinquance sexuelle, la sexualité et le rapport aux victimes et les victimisations antérieures ont été analysées pour compléter le portrait du fonctionnement de ces femmes. Les résultats de cette étude ont été confrontés aux représentations des travailleurs de ces centres recueillis à partir de Focus group. [less ▲]

Detailed reference viewed: 51 (1 ULg)
Peer Reviewed
See detailNON-PATHOLOGICAL AGING OF THE EXECUTIVE FUNCTIONS: INFLUENCE OF THE VAL108/158MET NUCLEOTIDE POLYMORPHISM OF THE COMT GENE
Gilsoul, Jessica ULg; Manard, Marine ULg; Collette, Fabienne ULg

Conference (2017, May 31)

Introduction. According to the Dual-State Theory of prefrontal cortex dopamine, Val/Val polymorphism of the COMT gene would favor better flexibility abilities, whereas Met/Met carriers would favor better ... [more ▼]

Introduction. According to the Dual-State Theory of prefrontal cortex dopamine, Val/Val polymorphism of the COMT gene would favor better flexibility abilities, whereas Met/Met carriers would favor better stability abilities. These genotypic effects should be magnified in older people, as a decrease in cognitive resources increases the influence of individual genetic differences on cognitive performance. Therefore, the aim of the study is to investigate the influence of the COMT Val108/158Met nucleotide polymorphism on executive functions in normal aging. Method. We assessed the executive processes of inhibition, shifting, and updating thanks to many different tasks in groups of young (n = 55) and aged participants (n = 45) carrying one of the three polymorphisms of the COMT gene (Val/Val, Val/Met, Met/Met). T-tests between our two groups (Young versus Aged) but also a 6 (Group: Young-Met/Met, Young-Val/Met, Young-Val/Val, Old-Met/Met, Old-Val/Met, and Old-Val/Val) X 3 (Executive functioning: Inhibition, Shifting, and Updating) repeated measure ANOVA with Executive functioning as within-subject factor (p < .05) were carried out. Results. Young and old participants significantly differed on the three executive functions. The comparison of genotypic groups showed no significant differences in young or older participants respectively. Interestingly, the Old-Val/Val group showed a lower performance than the young one on inhibition tasks. Discussion. As expected, we found an age effect on all the executive functions. The significant difference between the Young-Val/Val and the Old-Val/Val groups on inhibition suggests an age-related decrease in abilities requiring a stability component in individuals possessing a less favoring genotype for this component. [less ▲]

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See detailReligions et laïcités
Behrendt, Christian ULg; Christians, Louis-Léon

Conference given outside the academic context (2017)

Conférence donnée au Palais de Justice de Liège, le 30 mai 2017, à l'invitation de l'Association Saint-Yves, Liège.

Detailed reference viewed: 25 (2 ULg)
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See detailObservation and simulation of ethane at 22 FTIR sites
Mahieu, Emmanuel ULg; Franco, Bruno ULg; Pozzer, Andrea et al

Conference (2017, May 30)

Detailed reference viewed: 66 (6 ULg)
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See detailRégulation de voies de signalisation par deux acteurs de la voie Nonsense-mediated Decay, Dhx34 et Nbas: la cas particulier de l'adénohypophyse.
Windhausen, Thomas ULg

Doctoral thesis (2017)

In eukaryotes, biosynthesis of functional mRNAs is the core process of genetic expression and is monitored by highly conserved pathways that prevent appearance of aberrant mRNAs. Amongst them the Nonsense ... [more ▼]

In eukaryotes, biosynthesis of functional mRNAs is the core process of genetic expression and is monitored by highly conserved pathways that prevent appearance of aberrant mRNAs. Amongst them the Nonsense-Mediated Decay (NMD) pathway is the surveillance mechanism that detects and degrades mRNAs containing premature termination codons (PTCs). The translation of transcripts containing such nonsense codon within the coding sequence would leads to the production of C-terminally truncated proteins that could exhibit dominant negative or gain-of-function activities. The NMD is thus a key determinant of the phenotypic outcome of numerous diseases involving PTCs such as the β-thalassemia, the Duchenne muscular dystrophy or even some cancers. In addition to its quality control function degrading aberrant mRNA, the NMD is also involved in the abundance regulation of several physiological transcripts. For example the NMD is involved in the regulation of the concentration of splicing factors in a process called AS-NMD (Alternative splicing- Nonsense-mediated Decay), establish a threshold for some stress responses such as the UPR pathway (Unfolded Protein Response) and constitute a defence mechanism against ARN(+) viruses. Despite tremendous studies, the study of the developmental and physiological impact of the NMD pathway is restrained due to the early lethality of the mammals embryos that underwent knock-out of one of the NMD actor. As an alternative model we propose Danio rerio which as a vertebrate with external development and a large panel of genetic inactivation methods is a wonderful model for developmental studies and represent a excellent tool to study the NMD pathway. Initial studies in zebrafish conducted by morpholino knock-down, showed that depletion of upf1, upf2, smg5, smg6, dhx34 or nbas leads to the NMD blockage and induce similar developmental defects mainly in brain, eyes and somites. Moreover, it’s has been showed that as in mammals the NMD in fish also implicated in the regulation of natural transcripts. We present here a functional study of two key actors of the NMD, Dhx34 and Nbas, in the interesting case of the pituitary gland development. In the present study, we shed light on the NMD pathway importance for the developmental process of the pituitary gland. Using in situ hybridization confirmed by RT-qPCR quantification, we observed that the NMD inactivation thought inhibition of two crucial actors of this surveillance pathway, Dhx34 and Nbas, lead to a hypertrophy of the gland coupled with a promotion of the anterior cell fates and a repression of the posterior fates at 2 dpf. We proved that this endocrine deregulation is due to a late general increase of the Sonic Hedgehog and Delta-Notch signalling during AH formation. In addition to previous works, our results show that the NMD pathway is required to control the activity diverse signalling pathways involved in the developmental process. As confirmation, we could observe serious abnormalities in a variety of tissues such as underdeveloped eyes, intestine, liver and skeleton, defects in brain, somites and vascular patterning. [less ▲]

Detailed reference viewed: 21 (1 ULg)
See detailRoundtable moderator: Global Competition amongst Standard Setting Organizations
Van Cleynenbreugel, Pieter ULg

Scientific conference (2017, May 30)

I chaired/moderated and guided a discussion between A. Chaouat (Technicolor), A. Ganesh (CEN/CENELEC), Y. Meniere (European Patent Office) and S. Haber (Stanford University). I prepared an introductory ... [more ▼]

I chaired/moderated and guided a discussion between A. Chaouat (Technicolor), A. Ganesh (CEN/CENELEC), Y. Meniere (European Patent Office) and S. Haber (Stanford University). I prepared an introductory statement and questions for each panelist, in addition to moderating the discussion. [less ▲]

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Peer Reviewed
See detailLogical tools for descriptive psychology. Set theory and foundational mereology
Leclercq, Bruno ULg

Conference (2017, May 30)

Detailed reference viewed: 17 (2 ULg)
See detailImproved encapsulation of proteins within calcium carbonate microparticles by means of protein-polysaccharide complexes
Ramalapa, Bathabile ULg; Crasson, Oscar ULg; Vandevenne, Marylène ULg et al

Poster (2017, May 30)

The controlled delivery of proteins within calcium carbonate particles is currently widely investigated. The success of these carriers has been driven by the ionic interactions between proteins and ... [more ▼]

The controlled delivery of proteins within calcium carbonate particles is currently widely investigated. The success of these carriers has been driven by the ionic interactions between proteins and particles making the encapsulation of proteins highly dependent on the pH of reaction solutions and the isoelectric point of the protein. This poses a great limitation on the successful loading of proteins into microparticles. In this study we explored the use of polysaccharide-protein complexes to enhance the encapsulation of otherwise poorly encapsulated proteins in CaCO3 microparticles. A chitin binding domain (ChBD) was inserted on the protein β-lactamase to form a chimeric protein. A protein-polysaccharide complex was formed between the protein and hyaluronic acid (HA) owing to the intrinsic affinity of the ChBD to HA. The chimeric protein was then loaded into calcium carbonate (CaCO3) microparticles using super critical CO2 technology aided by the templating effect of HA on CaCO3. The microparticles were characterised for size, surface charge, poly-morphism and protein loading. Biochemical stability of the encapsulated β-lactamase was characterized by kinetic reaction with nitrocefin. The presence of the ChBD on the β-lactamase increased the encapsulation of the protein by 6 fold when complexed with HA. Thrombin mediated release increased the release of the protein from the microparticles within 36 hours from <25% to 87%. The protein-polysaccharide complex proved successful in enhancing the encapsulation of protein while retaining up to 81% activity and allowing controlled release of the protein by proteases. [less ▲]

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See detailPour un droit fondamental au logement : émergence et nuances
Quintart, Aurélie ULg

in Revue Générale de Droit Civil Belge = Tijdschrift voor Belgisch Burgerlijk (2017)

The fundamental right to housing is written in article 23 of our Constitution along with others social and economical rights since 1994. It is said to be a necessary component for the right to respect for ... [more ▼]

The fundamental right to housing is written in article 23 of our Constitution along with others social and economical rights since 1994. It is said to be a necessary component for the right to respect for human dignity. For the last decades, the right to housing has been quoted in many international declarations and conventions. However we still wonder: what is the real impact of this right to housing? How effective can it be? What interpretation can we give to case-law in this regard? We would like to bring some ideas and answer to the debate. Our article analyses the right to housing nowadays, as emerging out of treaties, laws and the international and national case-law. [less ▲]

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See detailImpact of circulation changes on the long-term trend of stratospheric hydrogen fluoride at five NDACC stations
Prignon, Maxime ULg; Bernath, P.F.; Blumenstock, T. et al

Poster (2017, May 29)

Hydrogen fluoride is mainly produced by the photolysis of anthropogenic source gases such as the chlorofluorocarbons (CFC), the hydrochlorofluorocarbons (HCFC) and the hydrofluorocarbons (HFC). These ... [more ▼]

Hydrogen fluoride is mainly produced by the photolysis of anthropogenic source gases such as the chlorofluorocarbons (CFC), the hydrochlorofluorocarbons (HCFC) and the hydrofluorocarbons (HFC). These families of species are known for contributing to ozone depletion and/or to the greenhouse effect. It is thus essential to regulate and monitor their emissions. Despite the fact that the Montreal protocol (1987) has succeeded to reduce and then suppress the CFC emissions, HF is still increasing in the stratosphere because of ongoing emissions of the HCFC and HFC substitution products. In the framework of the recent studies demonstrating the influence of stratospheric circulation changes on the trend of long-lived tracers (e.g. hydrogen chlorine), we decided to investigate the impact of these circulation changes on HF. To achieve this objective, the rates of changes over time of HF total/partial columns at various latitudes of the globe will be determined and critically discussed. Fourier Transform Infrared data produced at five NDACC sites (Kiruna – 68°N, Jungfraujoch – 46°N, Izana – 28°N, Lauder 45°S and Arrival-heights – 78°S) and satellite data (HALOE and ACE) will be used for this study. This preliminary selection of ground-based stations allows to cover both hemispheres and our period of investigation (last two decades). Finally, in order to support our data interpretation, two SLIMCAT simulations (standard and fixed dynamics) will also be included. [less ▲]

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See detailDesign and Management of Freight Transport Networks: Intermodal Transport and Externalities
Mostert, Martine ULg

Doctoral thesis (2017)

Transportation of goods contributes to the economic development of societies but it generates negative impacts on its environment called negative externalities. In its White Paper on Transport, the ... [more ▼]

Transportation of goods contributes to the economic development of societies but it generates negative impacts on its environment called negative externalities. In its White Paper on Transport, the European Commission encourages the flow transfer from road to more environmentally friendly modes like rail or inland waterways (IWW). This objective can be reached by the development of intermodal transport. A literature review on transport externalities and their valorization methods highlights the small number of studies related to the general modeling of transport externalities through dedicated mathematical formulas. However, the latter are important for identifying the key parameters that influence transport competitiveness in terms of externalities. This is demonstrated by analyzing two external cost functions for road and rail. The location of intermodal terminals stands out from the environmental perspective as one of the most important competitiveness factors of intermodal transport regarding road. An innovative mathematical model for the location of terminals and allocation of flows between road and intermodal rail and IWW transport is developed. The model is based on a bi-objective formulation which evaluates the trade-offs between transport operational costs and CO2 emissions. Economies of scale of intermodal transport are integrated. The model is applied to the Belgian network. Results indicate that terminal locations are relatively stable, whatever the optimized economic or environmental objective. The type of terminal located changes according to the followed strategy. Minimizing CO2 emissions leads to an increased use of intermodal transport. The impact of transport on air pollution is also evaluated. On the Belgian case, an economic optimization of transport operational costs is compared to an environmental optimization of transport air pollution external costs. The intervention of public authorities through a taxation policy for trucks is also studied. Results show that the introduction of road taxes leads to a more intensive use of intermodal transport than in the absence of taxes. The maximum intermodal market share is observed when air pollution external costs are minimized. Finally, a new model which considers other intermodal chains than the traditional “road-rail/IWW-road” modeling is applied on experimental data at the European level. The model allows to choose between any direct transport by one mode (road, rail or IWW), and any intermodal transport of up to three modes. Results indicate that several connections may benefit from the use of other combinations of modes than the “road-rail/IWW-road” combination. [less ▲]

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See detailLe Living Lab: une méthode parmi tant d'autres?
Elsen, Catherine ULg

Article for general public (2017)

Cette brève s’inscrit dans une série de publications destinées à partager les expériences et réflexions du WeLL. Ce mois-ci, nous nous attelons à repositionner l’approche Living Lab (son caractère centré ... [more ▼]

Cette brève s’inscrit dans une série de publications destinées à partager les expériences et réflexions du WeLL. Ce mois-ci, nous nous attelons à repositionner l’approche Living Lab (son caractère centré utilisateur, ses méthodes) au sein d’un panorama plus large de nouvelles manières de penser la créativité et l’innovation. En particulier, nous nous intéressons à deux approches complémentaires que sont le Design Thinking et le Creative Problem Solving (ou « C.P.S.»). [less ▲]

Detailed reference viewed: 54 (0 ULg)