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See detailQuels profils caractérisés par l'humeur, l'activation comportementale et les stratégies de régulation émotionnelle pouvons-nous identifier dans une population adulte ?
Wagener, Aurélie ULg

Conference (2015, May 22)

The behavioural model of depression put forward that the level of activities in depressed patients decreases which maintains their low mood. Depressed patients are also known to use non-adaptive cognitive ... [more ▼]

The behavioural model of depression put forward that the level of activities in depressed patients decreases which maintains their low mood. Depressed patients are also known to use non-adaptive cognitive coping strategies (e.g. rumination, catastrophizing). Previous research underlined that cognitive coping strategies predict the level of activation (non-adaptive cognitive coping strategies predict a low level of activation). According to the dimensional approach of psychopathology, we hypothesised that sub-groups of depressed and non-depressed adults could be identified depending on their level of activation and the kind of cognitive coping strategies they use. In order to test this hypothesis, we investigated the relationships between the level of activation, the cognitive coping strategies, anxiety and depression with a cluster-analysis approach. 762 adults (530 women, 232 men; mean age= 31.54, SD= 12.08) completed an online survey assessing the above-mentioned variables with self-reports measures (BADS-SF, CERQ, BDI-II, STAI-Y B). Results identified four clusters that differed according to the level of activation, the cognitive coping strategies, the anxiety and the depression. For instance, one of the four classes highlighted that non-active depressed adults used catastrophizing and rumination contrary to another classes of active non-depressed ones. These results, providing interesting guidelines for psychological interventions, will be discussed further during the congress. [less ▲]

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See detailElectron paramagnetic resonance and fluorescence studies on potential anticancer properties of two new Ru(II) complexes : preliminary results
Collienne, Simon ULg; Terrak, Mohammed ULg; Mouithys-Mickalad, Ange ULg et al

Poster (2015, May 22)

Fight against cancer is a priority of today’s research. Since the discovery of the anticancer properties of cisplatin (CisPt) in 1965 by Rosenberg [1], the treatment of cancer by chemotherapy has known ... [more ▼]

Fight against cancer is a priority of today’s research. Since the discovery of the anticancer properties of cisplatin (CisPt) in 1965 by Rosenberg [1], the treatment of cancer by chemotherapy has known great improvements. Unfortunately, CisPt has several side effects and is not effective against all kinds of cancer. Nevertheless its use highlights the great potential of organometallic compounds in the treatment of cancer [2]. Here we investigated the potential anticancer properties of two new organometallic compounds based on ruthenium II : [RuCl(p-cymene)(S2C.IDip)]+(PF6)- and [RuCl(p-cymene)(S2C.ICy)]+(PF6)-, named as LDO436 and LDO437 respectively. [less ▲]

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See detailModulatory effects of Ruthenium (II)-based complexes on oxidative stress induced by activated HL60 cells and Neutrophils
Mouithys-Mickalad, Ange ULg; Collienne, Simon ULg; Franck, Thierry ULg et al

Conference (2015, May 22)

There is a growing interest on the use of metal-based chemotherapeutic agents to fight different types of cancers [1]. The most used family of the organometallic compounds is platinum derivatives whose ... [more ▼]

There is a growing interest on the use of metal-based chemotherapeutic agents to fight different types of cancers [1]. The most used family of the organometallic compounds is platinum derivatives whose Cisplatin (CisPt) is the lead compound used for the treatment of various cancers including lung, testis, gastric, breast, etc. Nevertheless, beside its recognized therapeutic effects, side effects such as gastric toxicity and acute kidney failure were observed during the treatment, limiting its clinical use. Other compounds are currently studied and among them, Ruthenium (Ru) complexes have gained more importance for their less toxicity and lower aggressive effect on healthy tissues than CisPt. Ru-complexes are also more resorbed and excreted [2]. Numerous studies focused on the mechanisms of action of Ruthenium compounds to fight cancer, including antioxidant or pro-oxidant activity. During inflammation, activation and infiltration of neutrophils contribute to oxidant stress playing a crucial role in tumor development. Likewise, the degranulation of neutrophil causes the release of myeloperoxidase (MPO) which reacts with H2O2 to catalyze redox reactions. A therapeutic target to control inflammation is the modulation of oxidant enzymes and cells involved in radical species production and redox reactions. Because Ruthenium compounds can easily enter into cancer cells, a series of Ru(II)-complexes newly synthesized were used for this purpose. They were first tested for their radical scavenging activities using ABTS and 1,1-diphenyl-2-picrylhydrazyl (DPPH) assays. Amongst them, compound 1 (LD0436) and compound 2 (LD04037) were then studied for their ability to modulate the reactive oxygen species (ROS) production by inflammatory cells like human promyelocytic leukemia cell line (HL 60) and neutrophils (PMN) using fluorescence, chemiluminescence (CL) and electron spin resonance ESR techniques. The toxicity of those Ru-complexes against HL-60 and neutrophils was checked using Trypan blue exclusion assay. Altogether, CL and ESR findings indicate that both complexes 1 (LD0436) and 2 (LD0437) exhibit a dose-dependent inhibitory activity compared to CisPt, gallic acid, curcumin and quercetin, which were taken as reference molecules in the different systems investigated. Similarly, the tested complexes also display an antioxidant profile on the substrate oxidation catalyzed by peroxidase such as MPO mainly involved in acute and chronic inflammatory situations. 1: (RuCl(p-Cymen)(S2C.IDip)]+(PF6)-], 2: (RuCl(p-Cymen)(S2C.Icy)]+(PF6)-] References: 1. Ceresa C, Brawin A, Cavaletti G, Trinidad A et al., (2014) Current Medicinal Chemistry 20(21), 2237-2265. 2. Liu, Y, Zhang X, Zhang R, et al., (2011) European Journal of Inorganic Chemistry. 1974-1980. [less ▲]

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See detailLes concessions forestières des communautés locales : une avancée potentielle pour la foresterie sociale ? Perspectives dans un monde en déforestation
Vermeulen, Cédric ULg; Karsenty, Alain; Gillet, Pauline ULg

Conference given outside the academic context (2015)

La RDC vient d’adopter un décret qui met enfin en oeuvre la foresterie sociale en RDC, 12 ans après la promulgation de la loi. Ce décret suscite de nombreux espoirs quant à la mise en place d’une ... [more ▼]

La RDC vient d’adopter un décret qui met enfin en oeuvre la foresterie sociale en RDC, 12 ans après la promulgation de la loi. Ce décret suscite de nombreux espoirs quant à la mise en place d’une foresterie communautaire digne de ce nom en RDC. Quel est le champ des possibles ? Quelle influence potentielle en termes de déforestation ? [less ▲]

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See detailAlain Robbe-Grillet face à l'entretien journalistique : paradoxes
Lorent, Fanny ULg

Conference (2015, May 22)

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See detailAt the heart of Jupiter’s aurora; at the crossroads of Astrophysics Geophysics and Plasma Physics
Grodent, Denis ULg

Scientific conference (2015, May 21)

Auroral physics is at the intersection of more general fields of physics such as Astrophysics, Geophysics and Plasma Physics. In particular, the giant planets Jupiter and Saturn may be seen as slow ... [more ▼]

Auroral physics is at the intersection of more general fields of physics such as Astrophysics, Geophysics and Plasma Physics. In particular, the giant planets Jupiter and Saturn may be seen as slow rotating pulsars. For these two planets, there is a direct link between this pulsar-like behaviour and the auroral processes that are taking place in their atmosphere. We will take the example of Jupiter to illustrate haw the aurora is generated in the magnetosphere as a result of the volcanic activity of the moon Io. The ultraviolet aurora of Jupiter is conveniently described in terms of components located inside (poleward of) or outside (equatorward of) the main oval emission. However, these components may also be discriminated by their temporal behaviour, where the narrowest parts of the main “oval” remain relatively stable over time periods of several hours, and the satellite footprints show large variability with timescales of minutes. Inside the main emission, at the heart of the aurora, the so-called polar aurora, presumably corresponding to the polar cap mixing open and closed magnetic field lines, is characterized by rapid motions taking the form of swirls, giving rise to the “swirl region” and by beatings in the “active region”. This delicate auroral region is difficult to apprehend because of its ever-changing shape and because of the lack of appropriate tools to study it. [less ▲]

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See detailMaladaptive emotion regulation strategies and stress sensitivity mediate the relation between adverse life events and attenuated psychotic symptoms.
Laloyaux, Julien ULg; Dessart, Gregory; Van der Linden, Martial ULg et al

Poster (2015, May 21)

Introduction There is now solid evidence for a relation between Adverse Life Events (ALE) and psychotic symptoms in both patients with psychosis and in the general population. A recent study has shown ... [more ▼]

Introduction There is now solid evidence for a relation between Adverse Life Events (ALE) and psychotic symptoms in both patients with psychosis and in the general population. A recent study has shown that this relation may be partially mediated by stress sensitivity. However, other factors that may mediate this relation, such as emotion regulation strategies, have not yet been examined in the literature. Objective The aim of this study was to assess the mediation effect of both emotion regulation strategies and stress sensitivity in the relation between ALE and attenuated positive psychotic symptoms in the general population. Results Results demonstrated that the relation between ALE and attenuated positive psychotic symptoms (i.e. hallucinations and delusions) was mediated by maladaptive emotion regulations strategies. Discussion Although it is most likely that there are several possible trajectories leading to the formation of positive psychotic symptoms, the results of the present study suggest that one such trajectory may involve the maladaptive regulation of negative emotions alongside a certain vulnerability after experiencing highly distressing ALE. Hence, interventions aiming to enhance adaptive emotion regulation strategies and diminish the utilization of maladaptive strategies should be regarded as an integral part of psychological treatment schemes in the context of psychotic symptoms. Conclusion In summary, the present study demonstrated that the relation between ALE and attenuated positive psychotic symptoms is mediated by maladaptive emotion regulation strategies. [less ▲]

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See detailThe global grid for empowering renewable energy
Ernst, Damien ULg

Speech/Talk (2015)

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See detailCARRIAGE OF CLOSTRIDIUM DIFFICILE IN HOSPITAL PATIENTS IN SPAIN, INCLUDING MOLECULAR CHARACTERIZATION AND ANTIMICROBIAL SUSCEPTIBILITY OF THE ISOLATES
Rodriguez Diaz, Cristina ULg; Taminiau, Bernard ULg; Van Broeck, Johan et al

Poster (2015, May 21)

Increasing age, several co-morbidities, environmental contamination, antibiotic exposure and other intestinal perturbations appear to be the greatest risk factors for C. difficile infection (CDI ... [more ▼]

Increasing age, several co-morbidities, environmental contamination, antibiotic exposure and other intestinal perturbations appear to be the greatest risk factors for C. difficile infection (CDI). Therefore, hospitalized patients are considered particularly vulnerable to CDI. The main objective of this study was to evaluate the prevalence of C. difficile in a Spanish hospital and to characterize the isolates with respect to the PCR-ribotype, antibiotic resistance and toxin activity. In addition, multilocus sequence typing (MLST) was performed in order to study clonal relationships between C. difficile isolates obtained from two different countries. Culture of samples was performed in a selective medium cycloserine cefoxitin fructose cholate. An identification of the isolated colonies was done by PCR detection of tpi, tcdA, tcdB and cdtA genes. Toxic activity was confirmed by a cytotoxic immunoassay. Further characterization was performed by PCR ribotyping. MLST was used in order to determine genetic relationships between Spanish and Belgian C. difficile isolates recovered from hospital patients in both countries. C. difficile was frequently detected in hospitalized patients. The isolates belonged to different PCR ribotypes, including type 027. Most of the strains obtained harboured tcdA and tcdB genes. The number of positive faecal samples considerably increased among elderly patients over 65 years old. The multi-locus sequence typing (MLST) analysis showed that some Spanish and Belgian isolates cluster in the same lineage. This study reveals the circulation of toxigenic C. difficile in a Spanish hospital. The relatedness between Belgian and Spanish isolates indicate a common source or a lack of diversity from some PCR-ribotypes. Moreover, data obtained suggest that the combination of ribotyping and MLST is a good tool for the inter-laboratory comparison of strains among different countries. Continuous inter-country surveillance is suitable to understand the spread of C. difficile isolates among hospitalized patients. [less ▲]

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See detailAssessing employees propensity to engage in OCB: incremental validity of SJT beyond personality.
Lothe, Benoit ULg; Hansez, Isabelle ULg; Scius, Anthony et al

Conference (2015, May 21)

This study presents the validation results of a SJT developed in collaboration with a Belgian french speaking mutual insurance company for the assessment of employees OCB. The purpose is to provide ... [more ▼]

This study presents the validation results of a SJT developed in collaboration with a Belgian french speaking mutual insurance company for the assessment of employees OCB. The purpose is to provide empirical evidence concerning the validity of using the SJT by examining the issues of OCB criterion validity, incremental validity beyond a personality inventory, applicant perception and SJT transparency level. The SJT was developed in-house and following relevant literature recommendations (Weekley, Ployhart & Holtz, 2006). Data were collected on 117 white-collar employees. Three other measurements were concurrently collected: OCB using Williams & Anderson (1991) self-reported scales, personality using the Gosling, Rentfrow & Swann (2003) ten item inventory (TIPI) and applicant perception using SPJS (Bauer, & al., 2001). An open-ended question was used to access the extent to which applicants are able to identify the SJT criteria. Results indicated that the SJT is a relevant predictor of OCB (r = .42; p<.001). The SJT also provides incremental explanation of the OCB criteria beyond the personality inventory (∆R² = .11; p<.001). There was in average an agreement about the acceptability of the SJT in terms of perceived procedural justice. No relationships were found between applicant ability to correctly identify the SJT criteria and SJT score or OCB self-rating. This study is to our knowledge among the first attempt to develop and validate a tool to fill the gap on how to predict employees OCB (Organ, Podsakoff & Podsakoff, 2010). Implications for the personnel selection and current limitations will be discussed. [less ▲]

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See detailThe impact of ageing on episodic memory encoding: an fMRI study
François, Sarah ULg; Angel, Lucie; Salmon, Eric ULg et al

Poster (2015, May 21)

It is now commonly accepted that a decline in episodic memory is observed with ageing: while recollection processes are impaired, familiarity seems to be relatively preserved (a). Older individuals appear ... [more ▼]

It is now commonly accepted that a decline in episodic memory is observed with ageing: while recollection processes are impaired, familiarity seems to be relatively preserved (a). Older individuals appear to recruit prefrontal areas bilaterally when their encoding is successful, while in young adults this activation is found to be left-lateralized (b). In this study, we were interested in the differences between younger and older participant regarding cerebral activity during encoding depending on whether the item elicited recollection or familiarity during the recognition phase. Twenty young volunteers (aged 19 to 29 years old) and 19 older volunteers (aged 60 to 78 years old) were presented visual stimuli depicting objects. During a first fMRI session, they were asked to make a size judgement about them. Then, in a second phase, the subjects were shown the items previously encountered during the encoding phase, as well as distractors. Participants' task was to determine which one were new and which one were seen earlier. For the latter, they also performed a Remember-Know judgement. Data were analysed using SPM8, with an event design comparing modifications in cerebral activity between the two subjects groups during encoding (1) for the items leading to recollection during the recognition phase compared to those leading to familiarity, and (2) for the items associated with familiarity during the recognition phase compared to those which were not recognized. Results show that older adults display a heightened activity in the right middle frontal gyrus, medial cingulate and paracingulate left gyri as well as in the precuneus, bilaterally when they engage recollection processes. Amongst those regions, the precuneus seems to underlie compensatory processes, allowing the elderly to perform a richer encoding, as it was previously suggested for recollection processes during recall (c). However, no increase in activity was associated with familiarity processes in older adults, possibly because they are less demanding regarding attentional resources. (a) Bugaiska, A., Clarys, D., Jarry, C., Taconnat, L., Tapia, G., Vanneste, S., & Isingrini, M. (2007). The effect of aging in recollective experience: the processing speed and executive functioning hypothesis. Consciousness and Cognition, 16(4), 797-808. doi: 10.1016/j.concog.2006.11.007 (b) Duverne, S., Motamedinia, S., & Rugg, M. D. (2009). The relationship between aging, performance, and the neural correlates of successful memory encoding. Cerebral Cortex, 19(3), 733-744. doi:10.1093/cercor/bhn122 (c) Angel, L., Bastin, C., Genon, S., Balteau, E., Phillips, C., Luxen, A., . . . Collette, F. (2013). Differential effects of aging on the neural correlates of recollection and familiarity. Cortex, 49(6), 1585-1597. doi:10.1016/j.cortex.2012.10.002 [less ▲]

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See detailL'enfant parentifié: un enfant en souffrance
Haxhe, Stéphanie ULg

Conference given outside the academic context (2015)

Detailed reference viewed: 22 (2 ULg)
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See detailHow shattered flakes were used : Micro-wear analysis of quartz flake fragments
Knutsson, Helena; Knutsson, Kjel; Taipale, Noora ULg et al

in Journal of Archaeological Science: Reports (2015), 2

Prehistoric quartz assemblages have always posed a special problem for archaeologists. Due to its brittle nature, quartz is hard to understand within lithic classification systems that are based on ... [more ▼]

Prehistoric quartz assemblages have always posed a special problem for archaeologists. Due to its brittle nature, quartz is hard to understand within lithic classification systems that are based on formally varied flint assemblages. In this paper we explore ways to deal with this problem by applying two analytical methods, fracture analysis and use-wear analysis. A sample of 544 unmodified quartz flakes and flake fragments from Mesolithic and Neolithic sites in Sweden and Finland was analysed. It can be concluded that both whole and fragmented flakes were used as tools. Larger flakes and flake fragments were preferred as tool blanks and the type of use was correlated to variation in edge qualities rather than the formal characteristics of flakes. The results of this investigation suggest that making behavioural inferences from quartz assemblages with low formal variability requires the assemblages to be approached with a focus on functional types. [less ▲]

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See detailAcetylene (C2H2) and hydrogen cyanide (HCN) from IASI satellite observations: global distributions, validation, and comparison with model
Duflot, V.; Wespes, C.; Clarisse, L. et al

in Atmospheric Chemistry & Physics Discussions (2015), 15(10), 14357--14401

We present global distributions of C2H2 and HCN total columns derived from the Infrared Atmospheric Sounding Interferometer (IASI). These distributions are obtained with a fast method allowing to retrieve ... [more ▼]

We present global distributions of C2H2 and HCN total columns derived from the Infrared Atmospheric Sounding Interferometer (IASI). These distributions are obtained with a fast method allowing to retrieve C2H2 abundance globally with a 5% precision and HCN abundance in the tropical (subtropical) belt with a 10% (30%) precision. IASI data are compared for validation purposes with ground-based Fourier Transform Infrared (FTIR) spectrometer measurements at four selected stations. We show that there is an overall agreement between the ground-based and space measurements. Global C2H2 and subtropical HCN abundances retrieved from IASI spectra show the expected seasonality linked to variations in the anthropogenic emissions and seasonal biomass burning activity, as well as exceptional events, and are in good agreement with previous spaceborne studies. IASI measurements are also compared to the distributions from the Model for Ozone and Related Chemical Tracers, version 4 (MOZART- 4). Seasonal cycles observed from satellite data are reasonably well reproduced by the model. However, the model seems to overestimate (underestimate) anthropogenic (biomass burning) emissions and a negative global mean bias of 1% (16 %) of the model relative to the satellite observations was found for C2H2 (HCN). [less ▲]

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See detailAgroecology: Unity into diversity
Hatt, Séverin ULg; Artru, Sidonie ULg; Boeraeve, Fanny ULg et al

Poster (2015, May 21)

What does agroecology suggest ? Next to the theoretical agroecological principles, we present illustrative examples from farming practices, through the food system, up to the way of carrying agricultural ... [more ▼]

What does agroecology suggest ? Next to the theoretical agroecological principles, we present illustrative examples from farming practices, through the food system, up to the way of carrying agricultural research and education. [less ▲]

Detailed reference viewed: 25 (2 ULg)