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See detailRecent advances and improvements in computerized adaptive testing with the R package catR
Barrada, Juan Ramon; Magis, David ULg

Conference (2014, October 08)

The purpose of this talk is to present recent advances and developments of the R package catR. This package allows for random generation of response patterns under computerized adaptive testing (CAT) and ... [more ▼]

The purpose of this talk is to present recent advances and developments of the R package catR. This package allows for random generation of response patterns under computerized adaptive testing (CAT) and holds various options to select the first items, estimate ability, select the next item, stop the test and return final results. Two main improvements were realized. First, several rules for next item selection were added, among others, Kullback- Leibler, progressive and proportional methods. Second, catR was limited to dichotomous IRT models so far. The most recent update allows now for several polytomous IRT models, such as partial and generalized partial credit model, graded and modified graded response models, rating scale model, and nominal response model. All improvements will be shortly presented, both from a theoretical point of view and in terms of practical implementation in catR. If possible, several illustrative examples will be displayed in a short live demonstration of catR. [less ▲]

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See detailLe projet ECOBIOGAZ - Implications de l’équipe SAM (Sensing of Atmospheres and Monitoring) – Retour d’expérience d’une équipe spécialisée dans les atmosphères polluées dans un projet de méthanisation agricole
Adam, Gilles ULg; Molitor, Noémie ULg

Conference given outside the academic context (2014)

Projet ECOBIOGAZ La biométhanisation, passage obligé vers la réduction des émissions des gaz à effet de serre et l’indépendance énergétique de l’agriculture : est-elle une alternative économiquement ... [more ▼]

Projet ECOBIOGAZ La biométhanisation, passage obligé vers la réduction des émissions des gaz à effet de serre et l’indépendance énergétique de l’agriculture : est-elle une alternative économiquement rentable ? Le partenariat du projet considère aujourd’hui la biométhanisation comme le passage obligé vers une valorisation de la matière organique impropre à la consommation humaine et animale sous forme d’énergie et d’intrants pour l’agriculture. Noémie MOLITOR et Gilles ADAM expliqueront les grands axes du projet ainsi que les résultats de la recherche menée par l'équipe SAM (Sensing of Atmospheres and Monitoring). L'équipe s'est intéressée à l'emploi de nez électroniques pour aider au suivi de process dans les stations de méthanisation agricoles. Aussi, la nuisance olfactive de la méthanisation à la ferme et notamment des digestats est en cours d'évaluation. [less ▲]

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See detailContribution à l’étude du Plasma Riche en Plaquettes (PRP) dans le traitement des lésions tendineuses
Kaux, Jean-François ULg

Doctoral thesis (2014)

Platelet-rich plasma (PRP) may represent a new therapeutic option for chronic tendinopathies. Platelets release various cytokines and growth factors which promote angiogenesis, tissue remodeling, and ... [more ▼]

Platelet-rich plasma (PRP) may represent a new therapeutic option for chronic tendinopathies. Platelets release various cytokines and growth factors which promote angiogenesis, tissue remodeling, and wound healing. We made an extended literature review of the use of PRP in chronic tendinopathies. Despite the proven efficacy of PRP on tissue regeneration in experimental studies, there is currently scanty tangible clinical evidence with respect to its efficacy in chronic tendon disorders. The few studies that have been performed appear unlikely to be comparable. Randomized controlled studies with appropriate placebo groups are needed to determine the real effectiveness of PRP for treating chronic musculoskeletal injuries. After, we made a study to compare the platelet concentrations using 5 techniques of preparation of PRP and observed that each provides a very different PRP, with variations in the platelet concentrations and of the amount (if any) of erythrocytes and leucocytes. White blood cells could adversely affect wound healing through the release of proinflammatory factors responsible for extracellular matrix degradation. In addition, erythrocyte lysis releases free radicals that harm tissue structures. We thus think that ideal PRP should not contain any erythrocytes or leucocytes, and that the quality of the PRP could perhaps partially explain the variable results observed in the literature. The aim of our next study was to determine if an injection of PRP could improve the healing of sectioned Achilles tendons of rats. After surgery, rats received an injection of PRP (n = 60) or a physiological solution (n = 60) in situ. After 5, 15, and 30 days, 20 rats of both groups were euthanized and 15 collected tendons were submitted to a biomechanical test using cryo-jaws before performing transcriptomic analyses. Histological and biochemical analyses were performed on the five remaining tendons in each group. Tendons in the PRP group were more resistant to rupture at 15 and 30 days. The mechanical stress was significantly increased in tendons of the PRP group at day 30. Histological analysis showed a precocious deposition of fibrillar collagen at day 5 confirmed by a biochemical measurement. The expression of tenomodulin was significantly higher at day 5. The messenger RNA levels of type III collagen, matrix metalloproteinases 2, 3, and 9, were similar in the two groups at all time points, whereas type I collagen was significantly increased at day 30 in the PRP group. We concluded that an injection of PRP in sectioned rat Achilles tendon influences the early phase of tendon healing and results in an ultimately stronger mechanical resistance. Vascular endothelial growth factor (VEGF) is a platelet growth factor known to regulate angiogenesis. VEGF-111, a biologically active and proteolysis-resistant splice variant of this family, was recently identified. We made a study with the aim of evaluating whether VEGF-111 could have a therapeutic interest in tendon pathologies with the same rat protocol as our previous study. The force necessary to induce tendon rupture was greater for tendons of the VEGF-111 group (but less than the results obtained with the PRP in our previous study), while the section areas of the tendons were similar. The mechanical stress was similar at 5 and 15 days in both groups but was improved for the VEGF-111 group at day 30. No differences were observed in the mRNA expression of collagen III, tenomodulin and MMP-9. Finally, we made a study, the aim of which was to evaluate the clinical status and the return to sports activities in patients with chronic upper patellar tendinopathies, up to one year after a single infiltration of PRP. Twenty patients with chronic upper patellar tendinopathy were enrolled. Assessments were made before infiltration of PRP, and 6 weeks, 3 months and 1 year after the infiltration, using a 10-point Visual Analogic Scale, clinical examinations with a pressure algometer, algofunctional scores (IKDC and VISA-P), functional assessments (isokinetic and optojump evaluations) and imagery (ultrasounds and MRI). The PRP was obtained with an apheresis system (COM.TEC, Fresenius). Six millilitres of PRP were injected without local anaesthetic. One week after infiltration, patients started a standardised sub-maximal eccentric reeducation. We observed that with time, during the 1-year follow-up, VAS dropped significantly and both IKDC and VISA-P scores improved also significantly. During functional evaluation, it decreased as well, but without significant functional improvement. No improvements in the imagery measurements were observed. Younger patients seemed to be more susceptible to have a relief of pain by the PRP infiltration. Seventy percent of the patients reported a favourable evolution with decrease of pain, 15% reported no improvement and 15% were treated surgically. Seventy percent returned to sports activities, 64,3% without any pain and 50% recovered the same sports level. Even if 1 infiltration seems to be efficient in the indication of patellar tendinopathies, most studies evaluated the effects of 3 successive infiltrations. However, the multiplication of infiltrations risks increasing complications, and this treatment can be expensive. It seemed relevant to evaluate if 2 infiltrations of PRP would be more effective than only 1.Twenty patients suffering from jumper’s knee for more than 3 months were enrolled and randomized in 2 groups (1 or 2 infiltrations of PRP). The follow-up was made as follows: VAS, IKDC and VISA-P scores, algometer, isokinetic and ultrasounds evaluations. The concentration of the PRP used for each infiltration was similar in both groups, without any red or white blood cells. Results for all the evaluations did not show any difference between the groups. The comparison of 1 or 2 infiltrations of PRP did not show any difference between the 2 groups after a follow-up of 3 months. A second close infiltration of PRP to treat upper patellar tendinopathies is not necessary to improve the efficacy of this treatment in the short term. However, these results must be evaluated at a longer term. [less ▲]

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See detailL’Empire napoléonien dans l’espace
Lanneau, Catherine ULg

Conference given outside the academic context (2014)

Ce cours de 2h constitue la leçon inaugurale au module « Pensée et civilisation » de l'Espace universitaire liégeois, consacré, en 2014, au XIXe siècle sous ses divers aspects. Les cours-conférences à ... [more ▼]

Ce cours de 2h constitue la leçon inaugurale au module « Pensée et civilisation » de l'Espace universitaire liégeois, consacré, en 2014, au XIXe siècle sous ses divers aspects. Les cours-conférences à venir s’appesantiront sur des réalités politiques, sociales et juridiques qui feront naviguer l'auditoire du Premier Empire à la Belgique indépendante. Il semblait donc indispensable de préparer ces futures leçons en développant l’origine du Grand Empire, jusqu’à son apogée en 1812, et en s’attachant surtout à le définir dans l’espace. Or, pointer l’origine de l’Empire et de son territoire oblige, nécessairement, à envisager l’état de l’Europe en 1789, au moment où se déclenche la Révolution française. Il s'agit donc d'un parcours dans l'histoire française et européenne de 1789 à 1812. [less ▲]

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See detailDes vaches et des prairies : en faut-il encore ?
Beckers, Yves ULg

Conference given outside the academic context (2014)

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Peer Reviewed
See detailClassical analogy for the deflection of flux avalanches by a metallic layer
Brisbois, Jérémy ULg; Vanderheyden, Benoît ULg; Colauto, Fabiano et al

in New Journal of Physics (2014), 16(10), 103003

Sudden avalanches of magnetic flux bursting into a superconducting sample undergo deflections of their trajectories when encountering a conductive layer deposited on top of the superconductor. Remarkably ... [more ▼]

Sudden avalanches of magnetic flux bursting into a superconducting sample undergo deflections of their trajectories when encountering a conductive layer deposited on top of the superconductor. Remarkably, in some cases the flux is totally excluded from the area covered by the conductive layer. We present a simple classical model that accounts for this behaviour and considers a magnetic monopole approaching a semi-infinite conductive plane. This model suggests that magnetic braking is an important mechanism responsible for avalanche deflection. [less ▲]

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Peer Reviewed
See detail27èmes Entretiens Jacques Cartier
Lambert, Marie ULg

Conference (2014, October 07)

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See detailHow to manage HTA in 2014?
Krzesinski, Jean-Marie ULg

Conference (2014, October 07)

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Peer Reviewed
See detailA facile and fast electrochemical route to produce functional few-layer graphene sheets for lithium battery anode application
Ouhib, Farid ULg; Aqil, Abdelhafid ULg; Thomassin, Jean-Michel ULg et al

in Journal of Materials Chemistry A (2014), 2(37), 15298-15302

A simple approach for the production of polymer functionalized graphene nanosheets is reported. The resulting polyacrylonitrile chemisorbed on graphene sheets is made of 1 to 2 layers, with a large ... [more ▼]

A simple approach for the production of polymer functionalized graphene nanosheets is reported. The resulting polyacrylonitrile chemisorbed on graphene sheets is made of 1 to 2 layers, with a large majority of graphene single-layers. This novel functionalized graphene exhibits good cycling stability as an anode in Li-ion batteries without a conductive additive or binder. [less ▲]

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See detailHistoire des musiques africaines-américaines. Partim " Musiques religieuses noires, avant 1945"
Sacré, Robert ULg

Conference given outside the academic context (2014)

Robert Sacré : Histoire des musiques religieuses noires US avant 1945 (Negro spirituals et Jubuilee Songs http://culture.ulg.ac.be/musiquenoire Première partie : Avant 1945 Cette première partie sera ... [more ▼]

Robert Sacré : Histoire des musiques religieuses noires US avant 1945 (Negro spirituals et Jubuilee Songs http://culture.ulg.ac.be/musiquenoire Première partie : Avant 1945 Cette première partie sera consacrée à la naissance des musiques religieuses noires américaines, depuis les racines africaines jusqu’à la naissance des gospel songs. Pour comprendre cette évolution, Robert Sacré se penchera sur l’évangélisation des esclaves dans le nord, le centre et le sud du pays ; l’apparition des églises noires indépendantes et des sectes issues des églises baptistes et méthodistes ; la naissance des spirituals et des jubilee songs qui précèdent l’apparition du gospel, symbolisée par l’admission de tous les instruments de musique à l’Eglise et la composition de chants inspirés par les Evangiles. [less ▲]

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See detailIncrease in northern hemisphere stratospheric hydrogen chloride over recent years
Mahieu, Emmanuel ULg; Chipperfield, MP; Notholt, J et al

Poster (2014, October 07)

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See detailVan Gogh écrivain
Durand, Pascal ULg

Conference given outside the academic context (2014)

Van Gogh peint de 1880 à 1890. Vincent écrit de 1872 à 1890. De La Haye à Auvers-sur-Oise, en passant par le Borinage, Londres, Paris, Arles. Aux membres de sa famille, à diverses autorités religieuses ou ... [more ▼]

Van Gogh peint de 1880 à 1890. Vincent écrit de 1872 à 1890. De La Haye à Auvers-sur-Oise, en passant par le Borinage, Londres, Paris, Arles. Aux membres de sa famille, à diverses autorités religieuses ou professionnelles, à des peintres amis et à des critiques d’art. Jusqu’à la dernière lettre à Théo, du 23 juillet 1890, trouvée sur lui après son suicide : « Eh bien mon travail à moi j’y risque ma vie et ma raison y a fondrée à moitié — bon — mais tu n’es pas dans les marchands d’hommes ; pour autant que je sache et puisse prendre parti je te trouve agissant réellement et avec humanité mais que veux-tu ». Traversée des langues : néerlandais, anglais, français. Traversée aussi de la littérature. Celle qu’il lit et qu’il commente. Celle également qu’il met en représentation dans différentes natures mortes où vibre la présence de livres identifiables. La Bible et les Évangiles, Balzac et Michelet, Dickens et Beecher-Stowe, Maupassant et les Goncourt, Daudet et Zola. Ces textes, ces auteurs ne sont pas seulement des moyens d’évasion ou de sortie des rails de la locomotive à peindre que Van Gogh, selon sa propre expression, devient au cours des années 1880. Ils accompagnent, ils soutiennent, ils donnent sens à une expérience qui sans eux resterait largement informulée au-delà de considérations techniques et esthétiques propres à la peinture. Un éthos protestant s’y conjugue à un souci du réel passant par un goût tout particulier pour le réalisme en littérature. C’est ce double discours qu’il s’agira d’entendre à travers le très vaste corpus des lettres et quelques tableaux, à relire ou à revoir sous cet angle. [less ▲]

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See detailPrésentation de cas cliniques résolus ou non résolus
WANG, François-Charles ULg

Conference (2014, October 07)

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See detailSolar irradiance modelling over Belgium using Regional Climate Models within the frame of a day-ahead photovoltaic production forecasting system
Beaumet, Julien ULg; Doutreloup, Sébastien ULg; Fettweis, Xavier ULg et al

Poster (2014, October 06)

WRF-ARW and MAR climate models performances for the modelling of solar irradiances over Belgium are evaluated using in-situ measurements at Sart-Tilman and Daussoulx. Different WRF-ARW settings are tested ... [more ▼]

WRF-ARW and MAR climate models performances for the modelling of solar irradiances over Belgium are evaluated using in-situ measurements at Sart-Tilman and Daussoulx. Different WRF-ARW settings are tested. Sigmoid model proposed by Ruis-Ariaz etal. (2010) is used to decompose solar irradiance into direct and diffuse fraction. The performance of this model using measured and modelled global irradiances is also evaluated. [less ▲]

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See detailL'évolution du droit dans le temps et dans l'espace
Gerkens, Jean-François ULg

Scientific conference (2014, October 06)

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See detailPotential Proteomic Biomarkers Associated To Mucosal Healing In Crohn’s Disease
MEUWIS, Marie-Alice ULg; Baiwir, Dominique ULg; Mazzucchelli, Gabriel ULg et al

Poster (2014, October 06)

Introduction and objectives: In Crohn's disease (CD), there is a discrepancy between clinical activity of the disease (symptoms) and intestinal healing. However absence of tissue healing is associated ... [more ▼]

Introduction and objectives: In Crohn's disease (CD), there is a discrepancy between clinical activity of the disease (symptoms) and intestinal healing. However absence of tissue healing is associated with the risk of relapse and tissue damage progression. Endoscopy is costly and invasive. Hence biomarkers correlating with intestinal healing could improve disease management. We aimed to identify potential biomarkers associated to CD mucosal healing by a shotgun proteomics label free study. Methods: We used the STORI clinical trial cohort (n=103) aiming at identifying markers associated to relapse prediction after Infliximab treatment withdrawals. We used serum samples of patients in clinical remission, grouped according to the degree of intestinal healing seen at endoscopy. We performed depletion of the 20 most abundant plasma proteins on each serum pools and ran a proteomics label free differential analysis using 2D-nanoUPLC-MSE HDMS Synapt G1 for data acquisition and Protein Lynks Global Server vs 2.4 for data analysis (Waters, Corp., Milford, USA). Results and Discussion: We obtained potential biomarkers and designed a multiplexed -selected reaction monitoring (SRM) method for validation of these candidates in each individual patient. The method may also be tested in an independent set of IBD patients with and without mucosal healing. Conclusions: This research strategy and results of SRM validation of potential biomarkers associated to mucosal healing in this cohort of CD patients as well as the tests done on other CD patients, may provide new opportunities for CD follow-up tests development. [less ▲]

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