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See detailAnatomie et physiologie génitale bovine
Hanzen, Christian ULg; Nguyen, Kien Cuong

Learning material (2014)

La présentation concerne les rappels physiologiques et anatomiques du tractus génital de la vache. Traduite en vietnamien par le Dr. Nguyen Kien Cuong, doctorant au service de Theriogenologie de la ... [more ▼]

La présentation concerne les rappels physiologiques et anatomiques du tractus génital de la vache. Traduite en vietnamien par le Dr. Nguyen Kien Cuong, doctorant au service de Theriogenologie de la Faculté de Médecine Vétérinaire, elle a été donnée en aout 2014 aux étudiants de la faculté agrovétérinaire de l'université Nong Lam de HCMville [less ▲]

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See detailIs there a role for intra-arterial therapy or isolated liver perfusion?
DETRY, Olivier ULg

Conference (2014, October 10)

IS THERE A ROLE FOR INTRA-ARTERIAL THERAPY OR ISOLATED LIVER PERFUSION? Pr Olivier Detry, Dpt of Abdominal Surgery and Transplantation, CHU Liege, University of Liege, The liver is the most common ... [more ▼]

IS THERE A ROLE FOR INTRA-ARTERIAL THERAPY OR ISOLATED LIVER PERFUSION? Pr Olivier Detry, Dpt of Abdominal Surgery and Transplantation, CHU Liege, University of Liege, The liver is the most common visceral site of colorectal cancer (CRC) metastasis and recurrence. Approximately 25% of CRC patients present with synchronous hepatic metastases at time of initial diagnosis, and further 50% will develop metachronous metastases during the course of their illness. Unfortunately, only 25% of patients with hepatic CRC metastases are suitable for R0 resection at time of diagnosis or after chemotherapy. Intra‐arterial locoregional therapies are evolving tools in the management of CRC liver metastases. Although these therapies were initially used for salvage and palliation, they are becoming therapeutic options earlier in the course of disease in selected populations, to increase the rate of curative surgical resection, and to improve survival and quality of life. Furthermore, intra‐arterial therapies may serve as viable first‐line treatments for the large majority of patients who present with unresectable liver metastases, and as neoadjuvant chemotherapy prior to hepatectomy to minimize systemic effects. Hyperthermic isolated liver perfusion (HILP) has also been proposed by some groups as a mean to treat patients with unresectable liver metastases. Significant anti-tumoral effect has been demonstrated but HILP is a complicated procedure with a high morbidity. There remains a lack of robust, prospective randomized data for fair and balanced comparisons to be made between locoregional and modern systemic therapeutic modalities, as well as between locoregional therapies. Future RCTs addressing overall patient survival, tumor response and toxicity are required before any of these locoregional intra‐arterial treatments can be definitively recommended as the standard of care for hepatic colorectal liver mestastases. At the CHU of Liege, intra-arterial chemotherapy is now the usual way of administrating chemotherapy in patients with multiple CRC metastases limited to the liver after R0 liver resection. [less ▲]

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See detailPrediction of Regulatory Networks & Control of Secondary Metabolite Biosynthesis
Rigali, Sébastien ULg

Conference (2014, October 10)

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See detailWie und warum erinnert man an den Ersten Weltkrieg? Eine europäische Perspektive
Brüll, Christoph ULg

Scientific conference (2014, October 10)

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See detailSize Matters, Book Value does not! The Fama-French empirical CAPM revisited
Lambert, Marie ULg; Hübner, Georges ULg

Scientific conference (2014, October 10)

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See detailTournons le dos au mirage nucléaire!
Venanzi, Bruno; Chomé, Frédéric; Lemaire, Marc et al

Article for general public (2014)

Le report de la cessation d'activité des réacteurs Doel 1 et 2 à 2025 inquiète plusieurs acteurs environnementaux et associations actives dans le secteur des énergies vertes, qui dénoncent une erreur ... [more ▼]

Le report de la cessation d'activité des réacteurs Doel 1 et 2 à 2025 inquiète plusieurs acteurs environnementaux et associations actives dans le secteur des énergies vertes, qui dénoncent une erreur politique et économique majeure. Lettre ouverte au gouvernement fédéral. [less ▲]

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See detailLa prise en charge des facteurs de risque dans le diabète de type 2 est-elle optimale?
Krzesinski, Jean-Marie ULg

Scientific conference (2014, October 10)

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See detailEpigenetic regulation of macrophage polarisation
Hamaïdia, Malik ULg; Cosse, Jean-Philippe ULg; Willems, Luc ULg

Scientific conference (2014, October 10)

Présentation des résultats devant les promoteurs membres de l'axe 4 Agricuture is life (plateforme Gembloux AgroBiotech)

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See detailPrix littéraires, entre attention et prestige - le cas du Prix du Livre Allemand
Houscheid, Karin ULg

Conference (2014, October 10)

In 2013, the Hungarian writer Terézia Mora was awarded the German Book Prize for her novel "Das Ungeheuer" (The Monster). Her text contrasts with other more current and popular novels in terms of thematic ... [more ▼]

In 2013, the Hungarian writer Terézia Mora was awarded the German Book Prize for her novel "Das Ungeheuer" (The Monster). Her text contrasts with other more current and popular novels in terms of thematic content, textual form, and book design. As such, "Das Ungeheuer" does not really fit into the range of "technically properly narrated" literature that used to be awarded with the prize. Usually, the laureates of the German Book Prize were so-called "Familienromane" (family novels), a currently very popular genre. By honouring Mora, the jury attempted to increase and preserve the prestige of the young literary prize (awarded since 2005) that is based on the model of the French Prix Goncourt and the English Booker Prize. The German Book Prize had quickly fallen into disrepute with the German literary critics who characterize the Book Prize as a "sheer marketing prize" because it comes along with high ranks in German bestseller lists and many foreign rights sales for its laureates. As a new award, the German Book Prize has to position itself in the literary field. A detailed analysis of the prize and its laureates therefore allows us to observe how the struggle for prestige develops today and to consider the question whether "attention" can be considered a new form of capital that competes with Bourdieu's symbolic capital, or a variant form of symbolic capital in the current media-drenched (literary) society. In order to find an answer to this question I am going to confront the marketing and transfer strategies as well as the literary reception of the novels "Die Mittagsfrau" by Julia Franck (laureate in 2007) and "Das Ungeheuer" by Terézia Mora. [less ▲]

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See detailLettre ouverte aux négociateurs du prochain gouvernement fédéral : Ne vous laissez pas abuser par le mirage nucléaire !
Brouyaux, Antoinette; Chomé, Frédéric; Cloots, Lieze et al

Article for general public (2014)

S’il faut en croire les échos qui nous parviennent de vos négociations, vous vous seriez accordés sur un report de la mise à l’arrêt des réacteurs Doel 1 et 2 ; initialement prévue pour 2015, la cessation ... [more ▼]

S’il faut en croire les échos qui nous parviennent de vos négociations, vous vous seriez accordés sur un report de la mise à l’arrêt des réacteurs Doel 1 et 2 ; initialement prévue pour 2015, la cessation d’activité surviendrait in fine en 2025. Nous tenons à vous exprimer notre surprise, notre déception et notre crainte face à cette décision. [less ▲]

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See detailThe use of Ion Mobility Mass Spectrometry for isomer composition determination extracted from Se-rich yeast
Far, Johann ULg; Delvaux, Cédric ULg; Kune, Christopher ULg et al

in Analytical Chemistry (2014), just accepted

The isomer ratio determination of a selenium-containing metabolite produced by Se-rich yeast was performed. Electrospray Ionization and Ion Mobility Mass Spectrometry (IM-MS) were unsuccessfully used in ... [more ▼]

The isomer ratio determination of a selenium-containing metabolite produced by Se-rich yeast was performed. Electrospray Ionization and Ion Mobility Mass Spectrometry (IM-MS) were unsuccessfully used in order to resolve the isomers according to their Collisional Cross Section (CCS) difference. The isomer ratio determination of 2,3-dihydroxypropionylselenocystathionine was performed after multidimensional liquid chromatography preconcentration from a water extract of Se-rich yeast using preparative size exclusion, anion exchange and capillary reverse phase columns coupled to IM-MS. 4’-nitrobenzo-15-crown-5 ether, a Selective Shift Reagent (SSR), was added after the last chromatographic dimension in order to specifically increase the CCS of one of the isomers by the formation of a stable host-guest system with the crown-ether . Both isomers were consequently fully resolved by IM-MS and the relative ratio of the isomers was determined: 11-13% and 87-89%. The present data compared favorably with literature to support the analytical strategy despite the lack of authentic standard for method validation. In addition, computational chemistry methods were successfully applied to design the SSR and to support the experimental data. [less ▲]

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Peer Reviewed
See detailSustainability, Dynamic Capabilities, and Innovation
Crutzen, Nathalie ULg; Rammal, Hussain; Burritt, Roger

Conference (2014, October 09)

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See detailLe livre et la littérature dans le jeu vidéo
Barnabé, Fanny ULg

Conference given outside the academic context (2014)

La littérature et le jeu vidéo : deux domaines aux antipodes l’un de l’autre ? C’est ce que pourrait laisser penser le conflit de légitimité qui oppose ces deux médias dans l’imaginaire collectif : le ... [more ▼]

La littérature et le jeu vidéo : deux domaines aux antipodes l’un de l’autre ? C’est ce que pourrait laisser penser le conflit de légitimité qui oppose ces deux médias dans l’imaginaire collectif : le livre, symbole même de la culture, aurait peu en commun avec le jeu, souvent stigmatisé. Pourtant, dans les faits, les échanges entre ces deux domaines sont aussi fréquents que féconds. D’une part, la culture livresque constitue une influence essentielle du jeu vidéo sur le plan narratif, et l’objet-livre est un motif encore très régulièrement mobilisé par ce médium, que ce soit au sein des œuvres (comme dans la série des The Elder Scrolls) ou sous forme de complément ludique extérieur au jeu (comme dans les récents Wonderbook et Ni no Kuni). D’autre part, le jeu vidéo n’est pas sans effet sur l’évolution du format livresque (en témoignent les phénomènes de « gamification » des ebooks ou des « livres augmentés ») et constitue une thématique riche dont la littérature est aujourd’hui en train de s’emparer. Ces influences réciproques entre livre et jeu vidéo seront abordées lors d’une table-ronde animée par Björn-Olav Dozo (premier logisticien de recherche et maître de conférences à l’Université de Liège) et lors de laquelle communiqueront deux intervenants. Bruno Dupont est assistant en littérature allemande à l'Université de Liège et prépare actuellement un doctorat sur la représentation de l'ordinateur dans la littérature allemande du tournant du millénaire. Il travaille sur les thèmes du jeu vidéo comme phénomène culturel et procédé narratif, sur les liens entre littérature et cyberspace, et sur les mises en scène des nouvelles technologies et nouveaux médias dans la littérature. Fanny Barnabé est doctorante en Langues et lettres à l’Université de Liège. Diplômée en langues et littératures françaises et romanes, elle a réalisé son mémoire sur le thème de la narration vidéoludique. Actuellement, elle poursuit son doctorat sur les différents modes de réappropriation et de détournement du jeu vidéo par les joueurs, qu’elle étudie à travers quatre pratiques spécifiques : l’écriture de fanfictions, la réalisation de machinimas, le modding et le speedrun. [less ▲]

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See detailIntelligence Stratégique : Les chercheurs ont la parole …
Goffin, Dorothée ULg

Conference given outside the academic context (2014)

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See detailTraitement biologique anaérobie des déchets organiques : Comment tirer profit de la biomasse
Hiligsmann, Serge ULg

Scientific conference (2014, October 09)

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Peer Reviewed
See detailRecent advances and improvements in computerized adaptive testing with the R package catR
Barrada, Juan Ramon; Magis, David ULg

Conference (2014, October 08)

The purpose of this talk is to present recent advances and developments of the R package catR. This package allows for random generation of response patterns under computerized adaptive testing (CAT) and ... [more ▼]

The purpose of this talk is to present recent advances and developments of the R package catR. This package allows for random generation of response patterns under computerized adaptive testing (CAT) and holds various options to select the first items, estimate ability, select the next item, stop the test and return final results. Two main improvements were realized. First, several rules for next item selection were added, among others, Kullback- Leibler, progressive and proportional methods. Second, catR was limited to dichotomous IRT models so far. The most recent update allows now for several polytomous IRT models, such as partial and generalized partial credit model, graded and modified graded response models, rating scale model, and nominal response model. All improvements will be shortly presented, both from a theoretical point of view and in terms of practical implementation in catR. If possible, several illustrative examples will be displayed in a short live demonstration of catR. [less ▲]

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See detailLe projet ECOBIOGAZ - Implications de l’équipe SAM (Sensing of Atmospheres and Monitoring) – Retour d’expérience d’une équipe spécialisée dans les atmosphères polluées dans un projet de méthanisation agricole
Adam, Gilles ULg; Molitor, Noémie ULg

Conference given outside the academic context (2014)

Projet ECOBIOGAZ La biométhanisation, passage obligé vers la réduction des émissions des gaz à effet de serre et l’indépendance énergétique de l’agriculture : est-elle une alternative économiquement ... [more ▼]

Projet ECOBIOGAZ La biométhanisation, passage obligé vers la réduction des émissions des gaz à effet de serre et l’indépendance énergétique de l’agriculture : est-elle une alternative économiquement rentable ? Le partenariat du projet considère aujourd’hui la biométhanisation comme le passage obligé vers une valorisation de la matière organique impropre à la consommation humaine et animale sous forme d’énergie et d’intrants pour l’agriculture. Noémie MOLITOR et Gilles ADAM expliqueront les grands axes du projet ainsi que les résultats de la recherche menée par l'équipe SAM (Sensing of Atmospheres and Monitoring). L'équipe s'est intéressée à l'emploi de nez électroniques pour aider au suivi de process dans les stations de méthanisation agricoles. Aussi, la nuisance olfactive de la méthanisation à la ferme et notamment des digestats est en cours d'évaluation. [less ▲]

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See detailContribution à l’étude du Plasma Riche en Plaquettes (PRP) dans le traitement des lésions tendineuses
Kaux, Jean-François ULg

Doctoral thesis (2014)

Platelet-rich plasma (PRP) may represent a new therapeutic option for chronic tendinopathies. Platelets release various cytokines and growth factors which promote angiogenesis, tissue remodeling, and ... [more ▼]

Platelet-rich plasma (PRP) may represent a new therapeutic option for chronic tendinopathies. Platelets release various cytokines and growth factors which promote angiogenesis, tissue remodeling, and wound healing. We made an extended literature review of the use of PRP in chronic tendinopathies. Despite the proven efficacy of PRP on tissue regeneration in experimental studies, there is currently scanty tangible clinical evidence with respect to its efficacy in chronic tendon disorders. The few studies that have been performed appear unlikely to be comparable. Randomized controlled studies with appropriate placebo groups are needed to determine the real effectiveness of PRP for treating chronic musculoskeletal injuries. After, we made a study to compare the platelet concentrations using 5 techniques of preparation of PRP and observed that each provides a very different PRP, with variations in the platelet concentrations and of the amount (if any) of erythrocytes and leucocytes. White blood cells could adversely affect wound healing through the release of proinflammatory factors responsible for extracellular matrix degradation. In addition, erythrocyte lysis releases free radicals that harm tissue structures. We thus think that ideal PRP should not contain any erythrocytes or leucocytes, and that the quality of the PRP could perhaps partially explain the variable results observed in the literature. The aim of our next study was to determine if an injection of PRP could improve the healing of sectioned Achilles tendons of rats. After surgery, rats received an injection of PRP (n = 60) or a physiological solution (n = 60) in situ. After 5, 15, and 30 days, 20 rats of both groups were euthanized and 15 collected tendons were submitted to a biomechanical test using cryo-jaws before performing transcriptomic analyses. Histological and biochemical analyses were performed on the five remaining tendons in each group. Tendons in the PRP group were more resistant to rupture at 15 and 30 days. The mechanical stress was significantly increased in tendons of the PRP group at day 30. Histological analysis showed a precocious deposition of fibrillar collagen at day 5 confirmed by a biochemical measurement. The expression of tenomodulin was significantly higher at day 5. The messenger RNA levels of type III collagen, matrix metalloproteinases 2, 3, and 9, were similar in the two groups at all time points, whereas type I collagen was significantly increased at day 30 in the PRP group. We concluded that an injection of PRP in sectioned rat Achilles tendon influences the early phase of tendon healing and results in an ultimately stronger mechanical resistance. Vascular endothelial growth factor (VEGF) is a platelet growth factor known to regulate angiogenesis. VEGF-111, a biologically active and proteolysis-resistant splice variant of this family, was recently identified. We made a study with the aim of evaluating whether VEGF-111 could have a therapeutic interest in tendon pathologies with the same rat protocol as our previous study. The force necessary to induce tendon rupture was greater for tendons of the VEGF-111 group (but less than the results obtained with the PRP in our previous study), while the section areas of the tendons were similar. The mechanical stress was similar at 5 and 15 days in both groups but was improved for the VEGF-111 group at day 30. No differences were observed in the mRNA expression of collagen III, tenomodulin and MMP-9. Finally, we made a study, the aim of which was to evaluate the clinical status and the return to sports activities in patients with chronic upper patellar tendinopathies, up to one year after a single infiltration of PRP. Twenty patients with chronic upper patellar tendinopathy were enrolled. Assessments were made before infiltration of PRP, and 6 weeks, 3 months and 1 year after the infiltration, using a 10-point Visual Analogic Scale, clinical examinations with a pressure algometer, algofunctional scores (IKDC and VISA-P), functional assessments (isokinetic and optojump evaluations) and imagery (ultrasounds and MRI). The PRP was obtained with an apheresis system (COM.TEC, Fresenius). Six millilitres of PRP were injected without local anaesthetic. One week after infiltration, patients started a standardised sub-maximal eccentric reeducation. We observed that with time, during the 1-year follow-up, VAS dropped significantly and both IKDC and VISA-P scores improved also significantly. During functional evaluation, it decreased as well, but without significant functional improvement. No improvements in the imagery measurements were observed. Younger patients seemed to be more susceptible to have a relief of pain by the PRP infiltration. Seventy percent of the patients reported a favourable evolution with decrease of pain, 15% reported no improvement and 15% were treated surgically. Seventy percent returned to sports activities, 64,3% without any pain and 50% recovered the same sports level. Even if 1 infiltration seems to be efficient in the indication of patellar tendinopathies, most studies evaluated the effects of 3 successive infiltrations. However, the multiplication of infiltrations risks increasing complications, and this treatment can be expensive. It seemed relevant to evaluate if 2 infiltrations of PRP would be more effective than only 1.Twenty patients suffering from jumper’s knee for more than 3 months were enrolled and randomized in 2 groups (1 or 2 infiltrations of PRP). The follow-up was made as follows: VAS, IKDC and VISA-P scores, algometer, isokinetic and ultrasounds evaluations. The concentration of the PRP used for each infiltration was similar in both groups, without any red or white blood cells. Results for all the evaluations did not show any difference between the groups. The comparison of 1 or 2 infiltrations of PRP did not show any difference between the 2 groups after a follow-up of 3 months. A second close infiltration of PRP to treat upper patellar tendinopathies is not necessary to improve the efficacy of this treatment in the short term. However, these results must be evaluated at a longer term. [less ▲]

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See detailL’Empire napoléonien dans l’espace
Lanneau, Catherine ULg

Conference given outside the academic context (2014)

Ce cours de 2h constitue la leçon inaugurale au module « Pensée et civilisation » de l'Espace universitaire liégeois, consacré, en 2014, au XIXe siècle sous ses divers aspects. Les cours-conférences à ... [more ▼]

Ce cours de 2h constitue la leçon inaugurale au module « Pensée et civilisation » de l'Espace universitaire liégeois, consacré, en 2014, au XIXe siècle sous ses divers aspects. Les cours-conférences à venir s’appesantiront sur des réalités politiques, sociales et juridiques qui feront naviguer l'auditoire du Premier Empire à la Belgique indépendante. Il semblait donc indispensable de préparer ces futures leçons en développant l’origine du Grand Empire, jusqu’à son apogée en 1812, et en s’attachant surtout à le définir dans l’espace. Or, pointer l’origine de l’Empire et de son territoire oblige, nécessairement, à envisager l’état de l’Europe en 1789, au moment où se déclenche la Révolution française. Il s'agit donc d'un parcours dans l'histoire française et européenne de 1789 à 1812. [less ▲]

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