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See detailPolysaccharide-coated PCL nanofibers for wound dressing applications
Croisier, Florence ULg; Atanasova, Ganka; Poumay, Yves et al

in Advanced Healthcare Materials (in press)

Polysaccharide-based nanofibers with amultilayered structure are prepared by combining electrospinning (ESP) and layer-by-layer (LBL) deposition techniques. Charged nanofibers are firstly prepared by ... [more ▼]

Polysaccharide-based nanofibers with amultilayered structure are prepared by combining electrospinning (ESP) and layer-by-layer (LBL) deposition techniques. Charged nanofibers are firstly prepared by electrospinning poly(ε-caprolactone) (PCL) with a block-copolymer bearing carboxylic acid functions. After deprotonation of the acid groups, the layer-by-layer deposition of polyelectrolyte polysaccharides, notably chitosan and hyaluronic acid, is used to coat the electrospun fibers. A multilayered structure is achieved by alternating the deposition of the positively charged chitosan with the deposition of a negatively charged polyelectrolyte. The construction of this multi-layered structure is followed by Zeta potential measurements, and confirmed by observation of hollow nanofibers resulting from the dissolution of the PCL core in a selective solvent. These novel polysaccharide-coated PCL fiber mats remarkably combine the mechanical resistance typical of the core material (PCL) – particularly in the hydrated state –, with the surface properties of chitosan. The control of the nanofiber structure offered by the electrospinning technology, makes the developed process very promising to precisely design biomaterials for tissue engineering. Preliminary cell culture tests corroborate the potential use of such system in wound healing applications. [less ▲]

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See detailVascular calcification: from pathophysiology to biomarkers
EVRARD, Séverine ULg; DELANAYE, Pierre ULg; Kamel, S et al

in Clinica Chimica Acta (in press)

The link between vascular calcification (VC) and increased mortality is now well established. Over time, as clinical importance of this phenomenon has begun to be fully considered, scientists have ... [more ▼]

The link between vascular calcification (VC) and increased mortality is now well established. Over time, as clinical importance of this phenomenon has begun to be fully considered, scientists have highlightedmore and more physiopathological mechanisms and signaling pathways that underlie VC. Several conditions such as diabetes, dyslipidemia and renal diseases are undoubtedly identified as predisposing factors. But even if the process is better understood,many questions still remain unanswered. This reviewbriefly develops the various theories that attempt to explain mineralization genesis. Nonetheless, the main purpose of the article is to provide a profile of the various existing biomarkers of VC. Indeed, in the past years, a lot of inhibitors and promoters, which form a dense and interconnected network, were identified. Given importance to assess and control mineralization process, a focusing on accumulated knowledge of each marker seemed to be necessary. Therefore, we tried to define their respective role in the physiopathology and how they can contribute to calcification risk assessment. Among these, Klotho/fibroblast growth factor-23, fetuin-A, Matrix Gla protein, Bone morphogenetic protein-2, osteoprotegerin, osteopontin, osteonectin, osteocalcin, pyrophosphate and sclerostin are specifically discussed. [less ▲]

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See detaileffects of cholecaciferol supplementation and optimized calcium intakes on vitamin D status, muscle strength and bone haelth: a one-year pilot randomized controlled trial in adults with severe burns
ROUSSEAU, Anne-Françoise ULg; FOIDART-DESSALLE, Marguerite ULg; LEDOUX, Didier ULg et al

in Burns : Journal of the International Society for Burn Injuries (in press)

Objective: Burn patients are at risk of hypovitaminosis D and osteopenia or sarcopenia. Vitamin D pleiotropic effects may influence bone and muscle health. The aim of this pilot study was to assess ... [more ▼]

Objective: Burn patients are at risk of hypovitaminosis D and osteopenia or sarcopenia. Vitamin D pleiotropic effects may influence bone and muscle health. The aim of this pilot study was to assess effects of a cholecalciferol (VD3) supplementation and an optimized calcium (Ca) regimen on vitamin D (VD) status, bone and muscle health during sequelar stage of burn injury. Design: Monocentric randomized controlled trial. Methods: Fifteen adults with thermal burns dating from 2 to 5 years were randomized into two groups. For 12 months, they either received a quarterly IM injection of 200,000 IU VD3 and daily oral Ca (Group D) or placebo (Group P). VD status and bone remodeling markers were assessed every 3 months. Knee muscle strength and bone mineral density were, respectively, assessed using isokinetic dynamometry and dual X-ray absorptiometry at initiation (M0) and completion (M12) of the protocol. Results: Of all the patients, 66% presented with VD deficiency and 53% (with 3 men <40 y) were considered osteopenic at inclusion. After one year, calcidiol levels significantly increased in Group D to reach 40 (37–61) ng/ml. No significant change in bone health was observed in both groups while Group D significantly improved quadriceps strength when tested at high velocity. Conclusions: This VD3 supplementation was safe and efficient to correct hypovitaminosis D in burn adults. When combined with optimized Ca intakes, it demonstrated positive effects on muscle health but not on bone health. A high prevalence of hypovitaminosis D and osteopenia in these patients, as well as their wide range of muscle performances, seem to be worrying when considering rehabilitation and quality of life. [less ▲]

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See detailcompte rendu de : Eleanor DICKEY, The Colloquia of the Hermeneumata Pseudodositheana. Volume I. Colloquia Monacensia-Einsidlensia, Leidense-Stephani, and Stephani
Rochette, Bruno ULg

in Gnomon : Kritische Zeitschrift für die Gesamte Klassische Altertumswissenschaft (in press)

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See detailPersonnalité antisociale et psychopathologie
Englebert, Jérôme ULg

Conference (2015, July 14)

Notre communication a pour objectif de confronter les critères de la personnalité antisociale du DSM-IV et du DSM-5 à une réflexion psychopathologique. Nous commencerons par une analyse des différentes ... [more ▼]

Notre communication a pour objectif de confronter les critères de la personnalité antisociale du DSM-IV et du DSM-5 à une réflexion psychopathologique. Nous commencerons par une analyse des différentes contradictions propres au diagnostic qui nous mèneront à l’identification du critère « primaire » de cette entité qui est l’« incapacité à se conformer aux lois et normes sociales ». Nous confronterons ensuite à des situations cliniques l’hétérogénéité des profils pouvant répondre à ce diagnostic. Nos constats nous conduiront à mettre en doute la validité apparente du concept de personnalité antisociale, puisqu’il recouvre des modes de fonctionnement psychologique variés. La valeur discriminative faible, en matière de fonctionnement psychologique, suggère que c’est une dimension autre que psychopathologique qui organise ce diagnostic. Dénuée de toute attention pour les modes d’interactions, pour le vécu émotionnel et pour les états de subjectivité, la notion de personnalité antisociale ne porte pas d’intérêt à l’individu qu’elle catégorise, mais bien à l’acte délinquant commis par ce dernier. Nous conclurons sur le constat de l’absence de dimension psychopathologique de la personnalité antisociale, qui se révèle être un diagnostic principalement criminologique, à l’inverse des fondements de l’éthique psychopathologique. [less ▲]

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See detailSemiótica de la acción: textualización y notación
Dondero, Maria Giulia ULg

in Tópicos del seminario (2015), 31

Our essay focuses on some methodological issues concerning the semiotic analysis of practice. We will initially retrace the debate about the epistemological relationship between text and action, outlining ... [more ▼]

Our essay focuses on some methodological issues concerning the semiotic analysis of practice. We will initially retrace the debate about the epistemological relationship between text and action, outlining the forms of enunciative praxis through different levels of pertinence analysis. Secondly, we propose the concept of ‘textualization’ as a mediation between text and action: textualizations (photographs, videos, notes) organize and represent practices which are in themselves ephemeral and elusive. Finally, we will consider the textual diagrammatization that we call ‘notation’: this analytical form of mediation between text and practice does not have the same status of in-vivo textualisations, but it works like an ex-post reconstruction which highlights the main gestures and exchanges while performing their grammaticalization. A more general aim of this essay is an enquiry into the legitimate objects of textual semiotics: what are the objects that it can analyze without betraying its principle of immanence, but also without being confined to it and, as a consequence, being unable to analyze practices and respond to topical questions on social issues and on the research in the human sciences? [less ▲]

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See detailSubjectivations politiques et épreuve de soi. Le cas Sartre/Fanon
Cormann, Grégory ULg

Scientific conference (2015, March 05)

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See detailLes Grecs ont-ils étudié le latin ?
Rochette, Bruno ULg

Scientific conference (2015, February 19)

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See detailQuand la clinique bouscule les concepts
Englebert, Jérôme ULg

Scientific conference (2015, February 11)

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See detailEffects of low dose endosulfan exposure on brain neurotransmitter levels in the African clawed frog Xenopus laevis
Preud'Homme, Valérie; Milla, Sylvain; Gillardin, Virginie et al

in Chemosphere (2015), 120(2), 357-364

Understanding the impact of pesticides in amphibians is of growing concern to assess the causes of their decline. Among pesticides, endosulfan belongs to one of the potential sources of danger because of ... [more ▼]

Understanding the impact of pesticides in amphibians is of growing concern to assess the causes of their decline. Among pesticides, endosulfan belongs to one of the potential sources of danger because of its wide use and known effects, particularly neurotoxic, on a variety of organisms. However, the effect of endosulfan was not yet evaluated on amphibians at levels encompassing simultaneously brain neurotransmitters and behavioural endpoints. In this context, tadpoles of the African clawed frog Xenopus laevis were submitted to four treatments during 27 d: one control, one ethanol control, and two low environmental concentrations of endosulfan (0.1 and 1 μg L−1). Endosulfan induced a significant increase of brain serotonin level at both concentrations and a significant increase of brain dopamine and GABA levels at the lower exposure but acetylcholinesterase activity was not modified by the treatment. The gene coding for the GABA transporter 1 was up-regulated in endosulfan contaminated tadpoles while the expression of other genes coding for the neurotransmitter receptors or for the enzymes involved in their metabolic pathways was not significantly modified by endosulfan exposure. Endosulfan also affected foraging, and locomotion in links with the results of the physiological assays, but no effects were seen on growth. These results show that low environmental concentrations of endosulfan can induce adverse responses in X. laevis tadpoles. At a broader perspective, this suggests that more research using and linking multiple markers should be used to understand the complex mode of action of pollutants. [less ▲]

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See detailAntoine Galland et l'épigraphie
Famerie, Etienne ULg

in Bauden, Frédéric; Waller, Richard (Eds.) Colloque international A. Galland (2015, February)

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See detailLa démocratie sous expertise. Médias, think tanks et privatisation du débat européen (en préparation, parution début 2015)
Geuens, Geoffrey ULg

Book published by Éditions du Croquant, collection "Savoir / Agir" (2015)

L’ouvrage questionne la genèse des think tanks eurofédéralistes participant à la fabrication et à la légitimation des politiques d’intégration, avant de s’intéresser à ces autres agents sociaux de ... [more ▼]

L’ouvrage questionne la genèse des think tanks eurofédéralistes participant à la fabrication et à la légitimation des politiques d’intégration, avant de s’intéresser à ces autres agents sociaux de production et de diffusion de la pensée européenne que sont notamment les correspondants bruxellois et éditorialistes de quelques grands médias européens. L’ouvrage montre combien le discours journalistique sur l’Europe et le discours de certains « spécialistes » des questions européennes, qui trouve aussi à s’exprimer dans l’espace médiatique, sont la plupart du temps limités à quelques expressions stéréotypées et argumentaires clichés s’expliquant autant par la position occupée dans le champ du pouvoir par les agents qui s’en font les relais que par les dispositions de ces mêmes agents sociaux à l’égard du « projet européen ». [less ▲]

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See detailEffect of stress path on the miniaturizatio size effect for nickel polycrystals
Keller, Clement; Hug, Eric; Duchene, Laurent ULg et al

Conference (2015, January 04)

The mechanical behavior of mettalic materials deeply depends on the size of samples. For specimen dimensions de creasing from a few millimeters to a few micrometers, the general observed trend is a ... [more ▼]

The mechanical behavior of mettalic materials deeply depends on the size of samples. For specimen dimensions de creasing from a few millimeters to a few micrometers, the general observed trend is a softening of the mechanical behavior in tension which affects the stress level and the strain hardening. This effect is triggered by the derease of the number of grains across the thickness ( also called thickness"t" over grain size "d" ratio). The objective of this work is to provide new experimental results in order to analyse the miniaturization size effects for various stress paths without strain gradients across the thickness of the samples. To this aim, experimental tensil tests, large tensile tests and shear tests have been performed on Ni sheets ( 0.5mm) with various grain sizes ensuring different t/d ratios. Results show that the miniaturization softening is affected by triaxiality, the larger is this parameter, the lower is the mechanicval softening. These features seem to be linked to surface effects which are larger for low triaxiality stress paths. Attempts of numerical simulations using strain gradient crystal plasticity model are also performed to confirm the role played by surface effects. [less ▲]

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See detailA new species of Groenlandaspis Heintz, 1932 (Placodermi, Arthrodira) from the Famennian (Late Devonian) of Belgium
Olive, Sébastien ULg; Prestianni, Cyrille; Dupret, Vincent

in Journal of Vertebrate Paleontology (2015), 35(5),

A new species of the phlyctaeniid arthrodire genus Groenlandaspis from the upper Famennian of Belgium is described. The remains of Groenlandaspis potyi sp. nov. consist of dissociated thoracic armor ... [more ▼]

A new species of the phlyctaeniid arthrodire genus Groenlandaspis from the upper Famennian of Belgium is described. The remains of Groenlandaspis potyi sp. nov. consist of dissociated thoracic armor elements, but the specimen designed to be the holotype displays the median dorsal, anterior and posterior dorsolateral plates in connection. Though incomplete, the new species is characterized by an equilateral triangle-shaped median dorsal plate, a protruding posterodorsal apron of the posterior dorsolateral plate behind the overlap area for the median dorsal plate, and an overall lack of ornamentation. Groenlandaspis potyi sp. nov. constitutes the second occurrence of a Groenlandaspis species in continental Europe after the description of Groenlandaspis thorezi from upper Famennian quarries of Belgium. Another probable new species of Groenlandaspis is also described, though of unknown locality and horizon; it can however be deduced from the upper Famennian of Belgium without more precision. Together with some unpublished material of groenlandaspidids from the Famennian tetrapod-bearing locality of Strud, this material highlights the richness of the Groenlandaspididae diversity in Belgium. The discovery of Groenlandaspis potyi sp. nov. in Belgium reinforces the Famennian global distribution of this widespread genus during this period. Also, since those organisms have possibly been considered as non-marine indicators, this material is another argument pleading for close relationships between Euramerica and Gondwana around the Frasnian-Famennian boundary. [less ▲]

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See detailElsvier, Computers in Industry, Special Issue on Natural Language Processing and Text Analytics in Industry
Ittoo, Ashwin ULg; Bosh, v.d., Antal; Nguyen, Le Minh

Book published by Elsevier (2015)

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See detail"Des muets qui veulent parler". Lectures politiques, des Temps Modernes à L'Idiot de la famille
Cormann, Grégory ULg

in Bolmain, Thomas; Cormann, Grégory (Eds.) Politiques de la littérature. Bourdieu, Sartre, Foucault (2015)

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See detailRitournelles et territoires professionnels. Le cas des conseillers emploi
Orianne, Jean-François ULg

in Langage et Société (2015)

L’objectif de ce texte est d’utiliser le concept de ritournelle pour analyser la formation d’un groupe professionnel dans le champ des politiques d’emploi en Belgique : les conseillers emploi du FOREM ... [more ▼]

L’objectif de ce texte est d’utiliser le concept de ritournelle pour analyser la formation d’un groupe professionnel dans le champ des politiques d’emploi en Belgique : les conseillers emploi du FOREM. L’auteur commence par définir et opérationnaliser le concept, emprunté à Deleuze et Guattari, en suivant les apports des théories de la communication réflexive. Il esquisse brièvement le contexte politique et institutionnel au sein duquel le groupe professionnel apparaît. Ensuite, il analyse trois ritournelles professionnelles, trois procédés de territorialisation des identités professionnelles des conseillers emploi. Il précise, en conclusion, la complémentarité du concept de ritournelle avec celui de rhétorique professionnelle. [less ▲]

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See detailMamlūk Cairo: A Crossroad for Embassies
Bauden, Frédéric ULg; Dekkiche, Malika

Book published by Brill Academic Publishers (2015)

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See detailManuel. Les contrats spéciaux
Kohl, Benoît ULg; Burette, Caroline ULg; Daenen, Thomas et al

Book published by Larcier (2015)

Detailed reference viewed: 35 (8 ULg)