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See detail1915-2015: Het verhaal van de Belgische militaire inlichtingen- en veiligheidsdienst
Cools, Marc; Van Acker, Kathleen; Stans, David ULg et al

Book published by Maklu (2015)

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See detailPosttraumatisches Puppen-Syndrom. Gedanken zu Jean Michel d'Hoops Inszenierung "Borgia. Comédie contemporaine"
Wunsch-Viehöver, Vera ULg

in Das Andere Theater (2015), 88

compte-rendu sur "Borgia. Comédie contemporaine" de Thomas Gunzig, mise en scène par Jean-Michel d'Hoop, cie. Point Zéro

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See detailThird-party mesenchymal stem cell infusion in kidney transplant recipient: 6-month safety interim analysis
WEEKERS, Laurent ULg; ERPICUM, Pauline ULg; DETRY, Olivier ULg et al

in Transplant International (2015, November), 28(S4), 223-224278

Background: Mesenchymal stromal cell (MSC) have immunomodulating properties and could be used as immunosuppressive agents. We report the 6- month safety results for the 5 first patients treated with MSC ... [more ▼]

Background: Mesenchymal stromal cell (MSC) have immunomodulating properties and could be used as immunosuppressive agents. We report the 6- month safety results for the 5 first patients treated with MSC after kidney transplantation (KTx). Here, we address 3 specific safety issues: immunization against MSC and engraftment syndrome defined as acute graft dysfunction not related to rejection and over-immunosuppression. Patients and method: MSC production was carried out locally. MSC were not matched with kidney recipients’ HLA. Included patients were non-immunized, first transplant recipients from deceased donors. MSC (1.5–3.0 9 106/kg) infusion was planned 3 to 5 days post KTx. Patients with cardiovascular instability post KTx were excluded. All patients were treated with Basiliximab induction, Tacrolimus, Mycophenolate Mofetil and Steroid. We prospectively screened for anti-HLA antibodies at month 1, 3 and 6. Informed consent was obtained from all participants. The local ethical committee approved the protocol. Results: Collectively there were 23/50 and 29/50 HLA mismatches (MM) with kidney and MSC donor respectively, out of which 5 were shared MM. One patient developed de novo DSA, 2 patients anti-HLA antibodies against shared kidney/MSC MM and 1 patient developed 2 specific antibodies against MSC (MSCSA) at month 6. All antibodies were anti HLA class I except for 1. We did not observe any “engraftment” syndrome. Three patients experienced non- severe opportunistic infections: 1 CMV reactivation and 2 polyoma-BK virus viremia.Conclusion: We did not observe any strong safety signal. We did however observe some degree of immunization in 3 patients: 2 developed antibodies against shared kidney/MSC donor HLA MM and 1 MSCSA. [less ▲]

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See detailQuels instruments pour quelle croissance ?
Artige, Lionel ULg; Donnay, Philippe

in De Keuleneer, Eric; Rentier, Bernard; Artige, Lionel (Eds.) et al La croissance : réalités et perspectives. Actes du 21e Congrès des économistes belges de langue française. (2015)

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See detailBurundi: L'enseignement et apprentissage du français aux élèves rapatriés
Nshinyabashira, Guy-André ULg

Conference (2015, November)

Burundi: The teaching and learning of French returnees students Summary of the report 1965, 1969, 1972 and from April 2015 1988.1993 alas, Burundi lives recurrently a political-ethnic violence spiral that ... [more ▼]

Burundi: The teaching and learning of French returnees students Summary of the report 1965, 1969, 1972 and from April 2015 1988.1993 alas, Burundi lives recurrently a political-ethnic violence spiral that claimed the lives of hundreds of thousands of Burundian and forced into internal and external exile more one million Burundi. Since 2006, most of these exiles began returning voluntarily, while others are forcibly evicted from Tanzania to neighboring provinces of Burundi. In total, 478 865 people have been repatriated since 2002 and 95.068 in 2008. And since August 2013, following the political tensions between Rwanda (northern Burundi) and Tanzania (east and southern Burundi) 10,000 5à Burundi refugees were forcibly repatriated a week. People in school age integrate the education system in place where French is a language taught and teaching language. It was initiated in classes, intercultural dialogue of languages and cultures in contact between students who speak Swahili and English on one hand and on the other hand their hosts who speak Kirundi and French elementary level. However, resistors extending to verbal or physical violence are seen following their remoteness of linguistic realities of their migratory journey To achieve the objectives of social inclusion and school integration strategies have been implemented to allow newcomers to develop a practice more or less adequate French. Cultural sessions with spontaneous participation and freedom to use the language they master the most (French, English, Swahili and Kirundi) facilitated the initiation of a synergy in training in French with other languages of the course migration of our learners Based on a work tool, basic lexicon in four languages taught in Burundi in 2011 funded a priority solidarity fund for French cooperation I introduced theatrical improvisations activities such as motivational tools and learning about living together and reconciliation and for the personal development of learners pleasure of learning French and to learn French we have prepared and performed a sequence on reconciliation Patrice Faye and each repetition was , simultaneously, subject to a French lesson . This was a source of cohesion among our learners. The motivation was strengthened and despite their learning difficulties and communicate a positive report to the French language has gradually developed and installed. Note , for all practical purposes, a dramatic decision in 2006 , months after the end of a terrible war , was to install the compulsory teaching of languages in the first four primary year to a student population of six years following a 90% rural population . This was to teach simultaneously Kirundi (L1) , mother tongue, French (L2 ), English (L3) and Kiswahili (L4) , widespread language in the neighboring States. This measure was the subject of a scientific and political debate it is easy to guess. This issue has , subsequently made subject of my thesis project title ; " Burundi : The teaching and learning of French to college kids repatriated from Tanzania and the East of the DRC .Profils language , school conditions and educational proposals" Burundi : L’enseignement et apprentissage du français aux élèves rapatriés Résumé de la communication 1965, 1969, 1972, 1988,1993 et depuis avril 2015 hélas, le Burundi vit de manière récurrente une spirale de violences politico-ethnique qui a emporté la vie des centaines de milliers de burundais et contraint à l’exil intérieur et extérieur plus d’un million de burundais. Depuis 2006, la plupart de ces exilés ont commencé à rentrer de façon volontaire, tandis que d’autres sont expulsés de force de la Tanzanie, vers des provinces limitrophes du Burundi. Au total, 478.865 personnes ont été rapatriées depuis 2002, et 95.068 en 2008. Et depuis août 2013, suite aux tensions politiques entre le Rwanda (au nord du Burundi) et la Tanzanie (à l’Est et sud du Burundi), 5à 10.000 réfugiés burundais étaient rapatriés de force par semaine . Les personnes en âge scolaires intègrent le système éducatif en place où le français est une langue enseignée et langue d’enseignement. Il s’agissait d’initier, dans les classes, un dialogue interculturel des langues et cultures en contact entre les élèves qui parlent le swahili et l’anglais d’une part et d’autre part leurs hôtes qui parlent le kirundi et un français de niveau élémentaire. Cependant, des résistances allant jusqu’aux violences verbales voire physiques s’observent suite à leur éloignement des réalités linguistiques de leur parcours migratoire. Afin de réaliser les objectifs d’insertion sociale et d’intégration scolaire, des stratégies ont été mises en œuvre pour permettre aux nouveaux arrivants de développer une pratique plus ou moins suffisante du français. Des séances culturelles avec une participation spontanée et liberté d’utiliser la langue qu’on maîtrise le plus (français, anglais, swahili et le kirundi ) ont facilité la mise en route d’une formation en français en synergie avec les autres langues du parcours migratoire de nos apprenants en nous basant sur un outil de travail, Lexique de base en quatre langues enseignées au Burundi,2011 financé par un fonds de solidarité prioritaire de la coopération française . J’ai introduit des activités d’improvisations théâtrales, comme outils de motivation et d’apprentissage, sur le vivre ensemble et la réconciliation, puis, pour l’épanouissement personnel des apprenants au plaisir d’apprendre en français et d’apprendre le français, nous avons préparé et joué une séquence sur la réconciliation de Patrice FAYE et chaque répétition faisait, en même temps, objet d’une leçon de français. Ceci a été une source de cohésion entre nos apprenants. La motivation s’était renforcée et malgré leurs difficultés d’apprentissage et de communiquer, un rapport positif à la langue française s’est peu à peu élaboré et installé. Notons, pour toutes fins utiles, qu'une décision spectaculaire prise en 2006, quelques mois après la fin d'une épouvantable guerre, était d'installer l'enseignement obligatoire de quatre langues dès la première année du primaire, à une clientèle scolaire de six ans issue d'une population à 90 % rurale. Il s'agissait d'enseigner en même temps le kirundi (L1), langue maternelle, le français (L2), l'anglais (L3) et le kiswahili (L4), langue répandue dans les États voisins. Cette mesure a été l'objet d'un débat scientifique et politique qu'il est aisé de deviner. Cette question a, par la suite, fait objet du titre mon projet de thèse ; « Burundi : L’enseignement et apprentissage du français aux jeunes collégiens rapatriés de Tanzanie et de l’Est de la RDC .Profils linguistiques, conditions scolaires et propositions didactiques » [less ▲]

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See detailLa médiation animale comme espace intermédiaire de partenariat avec des animaux
Servais, Véronique ULg

Article for general public (2015)

Dans l’histoire des « zoothérapies », l’un des enjeux a été de distinguer ce qui relève du champ thérapeutique à proprement parler de ce qui relève plutôt d’activités récréatives ou de soutien. Nombreuses ... [more ▼]

Dans l’histoire des « zoothérapies », l’un des enjeux a été de distinguer ce qui relève du champ thérapeutique à proprement parler de ce qui relève plutôt d’activités récréatives ou de soutien. Nombreuses sont les associations qui ont vu se développer en leur sein des controverses, parfois houleuses et acerbes, à ce sujet. Nous proposons ici d’envisager l’introduction d’animaux dans un dispositif d’aide ou de soin comme une pratique de médiation au sens fort du terme, qui permet de créer ce que Winnicott appelait un espace intermédiaire, dans lequel des effets thérapeutiques peuvent survenir. [less ▲]

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See detailMars nighttime aurora
European Space Agency, ESA/ATG medialab; Gérard, Jean-Claude ULg; Soret, Lauriane ULg

E-print/Working paper (2015)

Press release by the European Space Agency (ESA) on the occasion of the publication in two journals of the peer-reviewed literature

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See detailSmall RNA deep sequencing identifies viral microRNAs during malignant catarrhal fever induced by alcelaphine herpesvirus 1
Sorel, Océane ULg; Tuddenham, Lee; Myster, Françoise ULg et al

in Journal of General Virology (The) (2015), 96(11), 3360-3372

Alcelaphine herpesvirus 1 (AlHV-1) is a c-herpesvirus (c-HV) carried asymptomatically by wildebeest. Upon cross-species transmission, AlHV-1 induces a fatal lymphoproliferative disease named malignant ... [more ▼]

Alcelaphine herpesvirus 1 (AlHV-1) is a c-herpesvirus (c-HV) carried asymptomatically by wildebeest. Upon cross-species transmission, AlHV-1 induces a fatal lymphoproliferative disease named malignant catarrhal fever (MCF) in many ruminants, including cattle, and the rabbit model. Latency has been shown to be essential for MCF induction. However, the mechanisms causing the activation and proliferation of infected CD8+T cells are unknown. Many c-HVs express microRNAs (miRNAs). These small non-coding RNAs can regulate expression of host or viral target genes involved in various pathways and are thought to facilitate viral infection and/or mediate activation and proliferation of infected lymphocytes. The AlHV-1 genome has been predicted to encode a large number of miRNAs. However, their precise contribution in viral infection and pathogenesis in vivo remains unknown. Here, using cloning and sequencing of small RNAs we identified 36 potential miRNAs expressed in a lymphoblastoid cell line propagated from a calf infected with AlHV-1 and developing MCF. Among the sequenced candidate miRNAs, 32 were expressed on the reverse strand of the genome in two main clusters. The expression of these 32 viral miRNAs was further validated using Northern blot and quantitative reverse transcription PCR in lymphoid organs of MCF- developing calves or rabbits. To determine the concerted contribution in MCF of 28 viral miRNAs clustered in the non-protein-coding region of the AlHV-1 genome, a recombinant virus was produced. The absence of these 28 miRNAs did not affect viral growth in vitro or MCF induction in rabbits, indicating that the AlHV-1 miRNAs clustered in this non-protein-coding genomic region are dispensable for MCF induction. [less ▲]

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See detailThe N-terminal region of CHD4 is essential for activity and contains a HMG-box-like-domain that can bind poly(ADP-ribose).
Silva, Ana; Ryan, Daniel; Galanty, Y et al

in Journal of Biological Chemistry (2015)

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See detailThe aggressive personality of an introduced fish affects foraging behavior in a polymorphic newt
Winandy, Laurane ULg; Denoël, Mathieu ULg

in Behavioral Ecology (2015), 26(6), 1528-1536

The study of personality has aroused much interest and has provided insight into the understanding of animal behavior. Nevertheless, the study of the ecological consequences of personality is a newer ... [more ▼]

The study of personality has aroused much interest and has provided insight into the understanding of animal behavior. Nevertheless, the study of the ecological consequences of personality is a newer field that could shed light on cases of alien species introductions. The goldfish (Carassius auratus) is frequently introduced worldwide and affects the abundance of newts, having an especially negative impact on an alternative phenotype, the paedomorph, which maintains larval traits at the adult stage, unlike the other phenotype, the metamorph, which has undergone metamorphosis. We experimentally assessed the impact of goldfish on the foraging behavior of both phenotypes of palmate newts (Lissotriton helveticus). More particularly, we assessed fish personality by analyzing the foraging activity and the aggressiveness toward newts, and newt personality by analyzing individual difference in boldness. In the presence of fish, fewer newts foraged than in their absence, and paedomorphs were more affected than metamorphs. We found strong personality differences in fish and fewer newts foraged in the presence of a more aggressive fish. Newts differed in boldness, but fish aggressiveness remains a key factor to explain newt behavior. Studying behavioral interactions between native and alien species helps to understand the mechanisms of coexistence and exclusion and why different phenotypes might be affected differently by the same threat. To a great extent, not only the presence of fish alters the foraging opportunities of newts but also the personality of the invader; integrating personality patterns of invaders is therefore a key to understanding the ecological consequences of alien species introduction. [less ▲]

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See detailRebates and Article 102 TFEU: The European Commission's Duty to Apply the Guidance Paper
Petit, Nicolas ULg

E-print/Working paper (2015)

This paper shows that the European Union (EU) courts' case-law and general principles of EU law place the European Commission (“Commission”) under a duty to apply the Guidance Communication on Enforcement ... [more ▼]

This paper shows that the European Union (EU) courts' case-law and general principles of EU law place the European Commission (“Commission”) under a duty to apply the Guidance Communication on Enforcement Priorities (“Guidance Paper”) in abuse of dominance cases started after its adoption. This duty includes the obligation to test Article 102 TFEU cases under the As Efficient Competitor (“AEC”) framework, as set out in the 2009 Guidance Paper. The judgments handed down by the Union courts in Intel v Commission and Post Danmark II do not alter in any way the Commission’s “self binding” duty to apply the Guidance Paper. If the Commission wishes to depart from the AEC framework, it must officially withdraw its Guidance Paper. [less ▲]

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See detailUne école doctorale européenne au service de la PSDC?
Paile, Sylvain ULg

Article for general public (2015)

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See detailSurface Constrained Elastic Rods with Application to the Sphere
Huynen, Alexandre ULg; Detournay, Emmanuel; Denoël, Vincent ULg

in Journal of Elasticity (2015)

The unilateral contact between an elastic rod and a rigid surface is encountered in numerous biological and engineering applications. Along continuous contacts, the centerline of the rod reflects the ... [more ▼]

The unilateral contact between an elastic rod and a rigid surface is encountered in numerous biological and engineering applications. Along continuous contacts, the centerline of the rod reflects the geometry of the constraining surface. This restriction of the rod axis to surface bound configurations enters its local equilibrium through a reaction pressure which ensures the compatibility between the deformation and the restraint geometry. The classic equations governing the static equilibrium of elastic rods are particularized to surface bound configurations by (i) specifying the location of the rod axis in terms of its coordinates in the parameter space associated with the constraining surface parameterization, and (ii) characterizing the orientation of its material frame through its rotation with respect to the surface normal. This formulation, which emphasizes the relations between the rod configuration and the geometry of the constraint, also leads to an expression for the reaction pressure. This approach is then validated on a spherical surface by comparing with known solutions for elastic curves, i.e., inextensible and twist free rods. [less ▲]

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See detailEtude technique et dendrochronologique de la roue découverte dans le puits du château fort de logne
Hoffsummer, Patrick ULg; Delye, Emmanuel ULg; Wéry, Benoit

in Frébutte, Christian (Ed.) Pré-actes des Journées d'Archéologie en Wallonie (2015, November)

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See detailL'échographie bovine: une autre utilité ... chez le veau
Sartelet, Arnaud ULg; Knapp, Emilie ULg; Rao, Anne-Sophie ULg et al

Conference given outside the academic context (2015)

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See detailGlobal optimization of the production and the distribution system for typical European HVAC systems
Randaxhe, François ULg; Lemort, Vincent ULg; Lebrun, Jean ULg

in Energy Procedia (2015), 78

European countries have agreed on a new 2030 Framework with a 30% improvement in energy efficiency compared to projection and a 40% cut in greenhouse gas emissions compared to 1990 levels. With an ... [more ▼]

European countries have agreed on a new 2030 Framework with a 30% improvement in energy efficiency compared to projection and a 40% cut in greenhouse gas emissions compared to 1990 levels. With an estimated 11% of all the electrical energy used in Europe consumed by HVAC systems, the improvement of their efficiency is a key element to reach these targets. When looking at the energy flow in typical European HVAC systems, one can observe important degradation in efficiency associated to heating and cooling energy transportation systems together with a non-optimal use of the production plant. These inefficiencies are direct consequences of the system design with, quite often, a lack of consideration of the system part load or its off-design operation. This research attempts to identify the sensitivity of both cooling and heating HVAC systems to these conditions and to propose an approach to optimize the design and the operation of HVAC systems integrated in buildings considering trade-off between primary systems efficiency, distribution losses and auxiliaries consumption. [less ▲]

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