Last 7 days     Results 1841-1860 of 10183.   88 89 90 91 92 93 94 95 96 97 98   Analyse des divergences entre forêts communautaires et permis de gré à gré au GabonMeunier, Quentin; Mombougou, Carl; Boldrini, Sylvie et alE-print/Working paper (2013)Detailed reference viewed: 27 (1 ULg) Managers’ competences in social enterprises: which specificities?Moreau, Charlotte ; Mertens de Wilmars, Sybille in Social Enterprise Journal (2013)The management of an organization and the context within which this organization evolves are recognized as two important aspects of any organization. Few studies have been conducted however on the ... [more ▼]The management of an organization and the context within which this organization evolves are recognized as two important aspects of any organization. Few studies have been conducted however on the management function within the specific context of social enterprises, organizations that mix social goals and economic imperatives (Darbus & Lazuech, 2010). This paper examines the specific competences of management in social enterprises, by constructing a competence model, the emblematic tool of competence-based management, relevant to the management of social enterprises (Colin & Grasser, 2007; Oiry & Sulzer, 2002; Retour & Rapiaux, 2006). Our hypothesis is that certain competences required of managers in social enterprises are specific, regarding the particular internal and external context of social enterprises, the governance model, etc. The methodology used is based on four main steps: a review of the literature and the conducting of exploratory interviews, the construction of a first draft of the competence model, the conducting of group interviews with managers of social enterprises in six European countries as this research takes place within the framework of a European research project on lifelong learning , and the final adaptation and validation of the competence model. [less ▲]Detailed reference viewed: 34 (4 ULg) Peut-on améliorer l'enseignement de concepts scientifiques par la mise en place d'un dispositif de collaboration en formation initiale des enseignants ?Poffé, Corentin in Puzzle (2013), 32(2), 100-102Detailed reference viewed: 6 (0 ULg) Zavalíaite, (Mn2+,Fe2+,Mg)3(PO4)2, a new member of the sarcopside group from the La Empleada pegmatite, San Luis Province, Argentina.Hatert, Frédéric ; Roda-Robles, Encarnacion ; de Parseval, Philippe et alin Canadian Mineralogist (2013), 50Detailed reference viewed: 1 (0 ULg) Mineralogy and geochemistry of phosphates and silicates in the Sapucaia pegmatite, Minas Gerais, Brazil: genetical implications.Baijot, Maxime ; Hatert, Frédéric ; Philippo, Simonin Canadian Mineralogist (2013), 50Detailed reference viewed: 3 (1 ULg) CNMNC guidelines for the use of suffixes and prefixes in mineral nomenclature, and for the preservation of historical names.Hatert, Frédéric ; Mills, Stuart; Pasero, Marco et alin European Journal of Mineralogy (2013), 25Detailed reference viewed: 1 (0 ULg) Rapid Plant Invasion in Distinct Climates Involves Different Sources of Phenotypic VariationMonty, Arnaud ; Bizoux, Jean-Philippe ; Escarré, José et alin PLoS ONE (2013), 8(1), 55627When exotic species spread over novel environments, their phenotype will depend on a combination of different processes, including phenotypic plasticity (PP), local adaptation (LA), environmental maternal ... [more ▼]When exotic species spread over novel environments, their phenotype will depend on a combination of different processes, including phenotypic plasticity (PP), local adaptation (LA), environmental maternal effects (EME) and genetic drift (GD). Few attempts have been made to simultaneously address the importance of those processes in plant invasion. The present study uses the well-documented invasion history of Senecio inaequidens (Asteraceae) in southern France, where it was introduced at a single wool-processing site. It gradually invaded the Mediterranean coast and the Pyrenean Mountains, which have noticeably different climates. We used seeds from Pyrenean and Mediterranean populations, as well as populations from the first introduction area, to explore the phenotypic variation related to climatic variation. A reciprocal sowing experiment was performed with gardens under Mediterranean and Pyrenean climates. We analyzed climatic phenotypic variation in germination, growth, reproduction, leaf physiology and survival. Genetic structure in the studied invasion area was characterized using AFLP. We found consistent genetic differentiation in growth traits but no home-site advantage, so weak support for LA to climate. In contrast, genetic differentiation showed a relationship with colonization history. PP in response to climate was observed for most traits, and it played an important role in leaf trait variation. EME mediated by seed mass influenced all but leaf traits in a Pyrenean climate. Heavier, earlier-germinating seeds produced larger individuals that produced more flower heads throughout the growing season. However, in the Mediterranean garden, seed mass only influenced the germination rate. The results show that phenotypic variation in response to climate depends on various ecological and evolutionary processes associated with geographical zone and life history traits. Seeing the relative importance of EME and GD, we argue that a “local adaptation vs. phenotypic plasticity” approach is therefore not sufficient to fully understand what shapes phenotypic variation and genetic architecture of invasive populations. [less ▲]Detailed reference viewed: 14 (5 ULg) Cartographie des Emissions annuelles de CO2 dues aux consommations énergétiques des bâtiments tertiaires en Région wallonne. Rapport de synthèse.Barbason, Mathieu ; Reiter, Sigrid Report (2013)Detailed reference viewed: 15 (1 ULg) Structural Behavior of Concrete Columns under Natural FiresGernay, Thomas ; Dimia, Mohamed Salahin Engineering Computations (2013), 30(6), Purpose - The paper aims to give an insight into the behavior of reinforced concrete columns during and after the cooling phase of a fire. The study is based on numerical simulations as these tools are ... [more ▼]Purpose - The paper aims to give an insight into the behavior of reinforced concrete columns during and after the cooling phase of a fire. The study is based on numerical simulations as these tools are frequently used in structural engineering. As the reliability of numerical analysis largely depends on the validity of the constitutive models, the development of a concrete model suitable for natural fire analysis is addressed in the study. Design/methodology/approach - The paper proposes theoretical considerations supported by numerical examples to discuss the capabilities and limitations of different classes of concrete models and eventually to develop a new concrete model that meets the requirements in case of natural fire analysis. Then, the study performs numerical simulations of concrete columns subjected to natural fire using the new concrete model. A parametric analysis allows for determining the main factors that affect the structural behavior in cooling. Findings – Failure of concrete columns during and after the cooling phase of a fire is a possible event. The most critical situations with respect to delayed failure arise for short fires and for columns with low slenderness or massive sections. The concrete model used in the simulations is of prime importance and the use of the Eurocode model would lead to unsafe results. Practical implications – The paper includes implications for the assessment of the fire resistance of concrete elements in a performance-based environment. Originality/value – The paper provides original information about the risk of structural collapse during cooling. [less ▲]Detailed reference viewed: 39 (16 ULg) Methodology for the Validation of Analytical Methods involved in Uniformity of Dosage Units testsRozet, Eric ; Ziemons, Eric ; Marini Djang'Eing'A, Roland et alin Analytica Chimica Acta (2013), 760Validation of analytical methods is required prior to their routine use. In addition, the current implementation of the Quality by Design (QbD) framework in the pharmaceutical industries aims at improving ... [more ▼]Validation of analytical methods is required prior to their routine use. In addition, the current implementation of the Quality by Design (QbD) framework in the pharmaceutical industries aims at improving the quality of the end products starting from its early design stage. However, no regulatory guideline or none of the published methodologies to assess method validation propose decision methodologies that effectively take into account the final purpose of developed analytical methods. In this work a solution is proposed for the specific case of validating analytical methods involved in the assessment of the Content Uniformity or Uniformity of Dosage Units of a batch of pharmaceutical drug products as proposed in the European or US pharmacopoeias. This methodology uses statistical tolerance intervals as decision tools. Moreover it adequately defines the Analytical Target Profile of analytical methods in order to obtain analytical methods that allow to make correct decisions about Content Uniformity or Uniformity of Dosage Units with high probability. The applicability of the proposed methodology is further illustrated using an HPLC-UV assay as well as a Near Infra-Red Spectrophotometric method. [less ▲]Detailed reference viewed: 36 (10 ULg) Interleukin-32 expression is associated with a poorer prognosis in head and neck squamous cell carcinoma.Guenin, Samuel; Mouallif, Mustapha ; Hubert, Pascale et alin Molecular Carcinogenesis (2013)Head and neck squamous cell carcinoma (HNSCC) represent the sixth most common malignancy diagnosed worldwide. Patient's survival is low due the high frequency of tumor recurrence. Inflammation promotes ... [more ▼]Head and neck squamous cell carcinoma (HNSCC) represent the sixth most common malignancy diagnosed worldwide. Patient's survival is low due the high frequency of tumor recurrence. Inflammation promotes carcinogenesis as well as the formation of metastasis. Indeed, proinflammatory mediators are known to stimulate the expression of specific transcription factors such as Snai1 and to increase the ability of tumor cells to migrate into distant organs. The atypical interleukin-32 (IL32) was mainly described to exacerbate inflammatory responses in rheumatoid arthritis and inflammatory bowel diseases. IL32 is expressed in various cancers but its role in HNSCC physiology is still unexplored. Here, we analyzed the expression of IL32 and its implication on HNSCC aggressiveness. We showed that patients with tumor expressing high amounts of IL32 exhibit decreased disease-free periods (20.5 mo vs. 41 mo, P = 0.0041) and overall survival (P = 0.0359) in comparison with individuals with weak IL32 tumor expression. This overexpression was negatively correlated with gender (P = 0.0292) and p53 expression (P = 0.0307). In addition, in vitro data linked IL32 expression to metastasis formation since IL32 inhibition decreased Snai1 expression and tumor cell migration in a Boyden chamber assay. Our data provide new insight into the role of IL32 in HNSCC aggressiveness. (c) 2013 Wiley Periodicals, Inc. [less ▲]Detailed reference viewed: 17 (4 ULg) Effect of extraction conditions on the yied and purity of ulvan extracted from Ulva lactucaYaich, Hela; Garna, Haikel; Besbes, Souhail et alin Food Hydrocolloids (2013)A study of the influence of extraction conditions (pH: 1.5 and 2; temperature: 80 °C and 90 °C; extraction time: 1-3 h), on the yield, chemical composition and purity of the sulphated cell wall ... [more ▼]A study of the influence of extraction conditions (pH: 1.5 and 2; temperature: 80 °C and 90 °C; extraction time: 1-3 h), on the yield, chemical composition and purity of the sulphated cell wall polysaccharides ulvan, extracted from the green seaweed Ulva lactuca and precipitated by alcohol is carried out. The alcohol precipitate yields varied from 21.68% to 32.67% (%dw/dw) depending on the pH. At pH 2, the alcohol precipitate yields and the uronic acid recovery from extract juice are higher than those obtained at pH 1.5. Other compounds than ulvan such as cellulose, hemicellulose, proteins and ash are solubilized from the cell walls of Ulva lactuca at both pH, and they are precipitated with alcohol. The alcohol precipitate obtained from different extraction conditions has high uronic acid (20.37%-23.60%) and neutral sugar content (20.09%-29.12%), especially when the conditions (pH, temperature) are drastic. It contains rhamnose (13.35%-15.59%), glucose (2.90%-10.97%), and xylose (2.36%-2.73%). A decrease in the molecular weight of ulvan was observed at acid pH, and for long extraction times. The presence of proteins (1.94%-2.32%) and inorganic material (33.36%-47.15%) in alcohol precipitate prove the lower purity of ulvan extracted and shows that ulvan precipitation with ethanol is not specific. © 2012 Elsevier Ltd. [less ▲]Detailed reference viewed: 18 (2 ULg) Root water uptake and water flow in the soil-root domainLobet, Guillaume ; Hachez, Charles; Chaumont, François et alin Amram, Eshel; Beeckman, Tom (Eds.) Plant Roots. The Hidden Half (2013)Detailed reference viewed: 24 (2 ULg) Impacts of occupant behaviours on residential heating consumption for detached houses in a temperate climate of the northern part of Europede Meester, Tatiana; Marique, Anne-Françoise ; De Herde, André et alin Energy & Buildings (2013), 57The occupants' behaviour has a great influence on the energy demand, management and consumption of a building. This paper investigates the influence of three parameters related to human behaviour through ... [more ▼]The occupants' behaviour has a great influence on the energy demand, management and consumption of a building. This paper investigates the influence of three parameters related to human behaviour through their modes of occupations (based on family size, management of the heating system and management of the heated area) on the housing heating loads of a standard dwelling in Belgium. Seven levels of insulation were tested: no insulation, two intermediate levels corresponding to 3 and 6 cm of insulation, the current standard for new buildings in Belgium, the low energy standard, the very low energy standard and the passive house standard. Multi-zone simulations were performed with a dynamic thermal simulation software. The impact of occupants' lifestyle and the interactions between occupation modes and insulation levels are highlighted. These results prove that the more the building is insulated, the more the lifestyle proportionally influences the heating loads. One important strategy for reducing heating consumption during the whole life cycle of the building is adapting the size of the house and its occupation modes to the evolution of family size. However, insulation is paramount, and increasing the insulation of the house provides generally better results than merely adapting the occupation mode. [less ▲]Detailed reference viewed: 56 (12 ULg) Probing the phase of the elastic $pp$ scattering amplitude with vortex proton beamsIvanov, Igor in AIP Conference Proceedings (2013)We show that colliding vortex proton beams instead of (approximate) plane waves can lead to a direct measurement of how the overall phase of the scattering amplitude changes with the scattering angle. In ... [more ▼]We show that colliding vortex proton beams instead of (approximate) plane waves can lead to a direct measurement of how the overall phase of the scattering amplitude changes with the scattering angle. In elastic $pp$ scattering, this will open a novel way to measure the parameter $\rho(t)$ and probe the real part of the Pomeron. [less ▲]Detailed reference viewed: 9 (1 ULg) Symmetries in multi-Higgs-doublet modelsIvanov, Igor ; Vdovin, Evgenyin AIP Conference Proceedings (2013)We report the recent progress in understanding of symmetries which can be implemented in the scalar sector of electroweak symmetry breaking models with several Higgs doublets. In particular we present the ... [more ▼]We report the recent progress in understanding of symmetries which can be implemented in the scalar sector of electroweak symmetry breaking models with several Higgs doublets. In particular we present the list of finite reparametrization symmetry groups which can appear in the three-Higgs-doublet models. [less ▲]Detailed reference viewed: 13 (1 ULg) Carnet de pédiatrie: hématologie et douleur de l'enfantBattisti, Oreste ; DRESSE, Marie-Françoise Learning material (2013)Detailed reference viewed: 25 (2 ULg) Synthesis of poly(vinyl acetate)-b-poly(vinyl chloride) block copolymers by cobalt-mediated radical polymerization (CMRP)Piette, Yasmine; Debuigne, Antoine ; Bodart, Vinent et alin Polymer Chemistry (2013), 4(5), 1685-1693The synthesis of poly(vinyl acetate)-b-poly(vinyl chloride) (PVAc-b-PVC) block copolymers by Cobalt-Mediated Radical Polymerization (CMRP) is investigated for the first time in this paper. A PVAc–Co(acac ... [more ▼]The synthesis of poly(vinyl acetate)-b-poly(vinyl chloride) (PVAc-b-PVC) block copolymers by Cobalt-Mediated Radical Polymerization (CMRP) is investigated for the first time in this paper. A PVAc–Co(acac)2 macroinitiator is prepared by CMRP using the V-70/Co(acac)2 binary system or a preformed alkylcobalt(III) compound. Then, the block copolymerization occurs in the bulk at 40 °C by the addition of VC. The addition of water to the polymerization medium or the slow generation of alkyl radicals during the whole polymerization is beneficial to the process by consuming part of the excess of deactivator (Co(acac)2) that blocks the polymer chains into the dormant form. Dynamic light scattering (DLS) measurements and AFM analyses evidence that the PVAc-b-PVC forms core–shell micelles in a selective solvent of the PVAc block, i.e. methanol, evidencing the blocky structure of the copolymer. PVAc-b-P(VC-co-VAc) copolymers are also successfully prepared by initiating the radical copolymerization of VC and VAc at 40 °C from a PVAc–Co(acac)2 macroinitiator. [less ▲]Detailed reference viewed: 15 (3 ULg) Echocardiographic integrated backscatter for detecting progression and regression of aortic valve calcifications in rats.Roosens, Bram; Bala, Gezim; Gillis, Kris et alin Cardiovascular Ultrasound (2013), 11(1), 4ABSTRACT: BACKGROUND: Calcification is an independent predictor of mortality in calcific aortic valve disease (CAVD). The aim of this study was to evaluate the use of non-invasive, non-ionizing ... [more ▼]ABSTRACT: BACKGROUND: Calcification is an independent predictor of mortality in calcific aortic valve disease (CAVD). The aim of this study was to evaluate the use of non-invasive, non-ionizing echocardiographic calibrated integrated backscatter (cIB) for monitoring progression and subsequent regression of aortic valvular calcifications in a rat model of reversible renal failure with CAVD, compared to histology. METHODS: 28 male Wistar rats were prospectively followed during 21 weeks. Group 1 (N=14) was fed with a 0.5% adenine diet for 9 weeks to induce renal failure and CAVD. Group 2 (N=14) received a standard diet. At week 9, six animals of each group were killed. The remaining animals of group 1 (N=8) and group 2 (N=8) were kept on a standard diet for an additional 12 weeks. cIB of the aortic valve was calculated at baseline, 9 and 21 weeks, followed by measurement of the calcified area (Ca Area) on histology. RESULTS: At week 9, cIB values and Ca Area of the aortic valve were significantly increased in the adenine-fed rats compared to baseline and controls. After 12 weeks of adenine diet cessation, cIB values and Ca Area of group 1 decreased compared to week 9, while there was no longer a significant difference compared to age-matched controls of group 2. CONCLUSIONS: cIB is a non-invasive tool allowing quantitative monitoring of CAVD progression and regression in a rat model of reversible renal failure, as validated by comparison with histology. This technique might become useful for assessing CAVD during targeted therapy. [less ▲]Detailed reference viewed: 13 (3 ULg) Two-Parameter Kinematic Theory for Shear Behavior of Deep BeamsMihaylov, Boyan ; Bentz, Evan; Collins, Michaelin ACI Structural Journal (2013), 110(3), 447-455This paper presents a kinematic model for deep beams capable of describing the deformed shape of such members in terms of just two primary parameters. The kinematic model is combined with equilibrium ... [more ▼]This paper presents a kinematic model for deep beams capable of describing the deformed shape of such members in terms of just two primary parameters. The kinematic model is combined with equilibrium equations and stress-strain relationships to form a theory to predict the shear strength and deformations patterns of deep beams at shear failure. These deformation patterns include crack widths, maximum deflections, and the complete displacement field for the beam. The kinematic theory predicts the components of shear strength of deep beams and how they vary with a/d ratio. These components indicate a significant size effect for the shear strength of deep beams even for members with transverse reinforcement. The theory has been validated against a large number of experimental results. [less ▲]Detailed reference viewed: 31 (17 ULg)