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See detailStatistiques et méthodes de recherche (Biostatistiques)
Vander Haegen, Marie ULiege

Learning material (2017)

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See detailCrossoads ( septembre 2017) - chaque mercredi de 18h à20h - rediffusion: samedis de 22h à minuit
Sacré, Robert ULiege

Diverse speeche and writing (2017)

Programme radio hebdomadaire consacré aux musiques africaines-américaines ; streaming : www.equinoxefm.be ; podcasts www.mixcloud.com/robertsacre9

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See detailTraduction de l'article de Scott M. Bock : CLASSIE BALLOU "Classy" Swamp Blues
Sacré, Robert ULiege

in ABS Magazine (2017), (ABS MAG # 57),

Biographie de Classie Ballou, un musicien noir de Louisiane ; photos

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See detailVariétés - 1. Froment d'hiver
Meza Morales, Walter ULiege; Dumont, Benjamin ULiege; Jacquemin, Guillaume et al

in Watillon, Bernard; Bodson, Bernard (Eds.) Livre Blanc Céréales (2017, September)

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See detailDO MESENCHYMAL STROMAL CELLS PROMOTE HLA SPECIFIC ANTIBODIES FORMATION AFTER INFUSION IN LIVER TRANSPLANT RECIPIENTS?
VANDERMEULEN, Morgan ULiege; MAGGIPINTO, Gianni ULiege; JOURET, François ULiege et al

in Transplant International (2017, September), 30(S2), 548051

Background: Mesenchymal stromal cells (MSC) immunogenicity is debated. We recently published a prospective, controlled, phase I study evaluating a single administration of third-party MSC in 10 liver ... [more ▼]

Background: Mesenchymal stromal cells (MSC) immunogenicity is debated. We recently published a prospective, controlled, phase I study evaluating a single administration of third-party MSC in 10 liver transplant recipients (LTR). Here, we focus on the development of antibodies (Ab) against MSC-donor HLA (MSCDSA) in LTR following MSC infusion. Methods: Ten LTR under standard immunosuppression received 3rd-party unrelated MSC on postoperative day 3, and were prospectively compared to 10 control LTR. Recipients and donor of either liver or MSC were genotyped for HLA A/B/C/DR/DQ. Recipients were tested for HLA Ab before and 1, 3 and 6 months after transplant by Luminex". Ab were considered as positive in case of MFI >1500 and in accordance with the manufacturer’s recommendations. Results: In MSC-treated group, 2 patients showed pre-transplant MSCDSA. During follow-up, MSCDSA were detected in 6 additional patients who had received multiple red blood cell allo-transfusions before and/or rapidly after transplant. These patients also developed Ab against various MSC-unrelatedHLA. Two patients did not develop any MSCDSA throughout the follow-up, and one of them did not receive any allo-transfusion. MFI of detected MSCDSA were not significantly different from MFI of other detected HLA Ab. In control group, 3 patients were sensitized pre-transplant, and 6 patients developed de novo multiple HLA Ab. Four of these had received multiple allo-transfusions. Conclusion: In the large pool of HLA Ab identified in LTR post transplant, the detection of MSCDSA is most likely caused by allo-transfusions rather than related to MSC infusion. Further studies are required to confirm that MSC are “immune privileged”. [less ▲]

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See detailAdministration of mesenchymal stromal cells before renal ischemia/reperfusion attenuates kidney injury and modulates renal lipid metabolism in rats
ERPICUM, Pauline ULiege; Rowart, Pascal ULiege; POMA, Laurence ULiege et al

in Transplant International (2017, September), 30(S2), 9004

Background: Mesenchymal stromal cells (MSC) have been demonstrated to attenuate renal ischemia/reperfusion (I/R) damage in rodents. The mecha- nisms of such nephroprotection remain unclear. Materials and ... [more ▼]

Background: Mesenchymal stromal cells (MSC) have been demonstrated to attenuate renal ischemia/reperfusion (I/R) damage in rodents. The mecha- nisms of such nephroprotection remain unclear. Materials and Methods: Male Lewis rats aged of 8–10 weeks received tail i.v injection of 1.5x106 MSC in 1 mL saline (MSCD-7, n = 11) or saline alone (SD- 7, n = 6) 7 days before renal I/R. Left renal ischemia (by clamping the renal pedicle) lasted 45 min. Right nephrectomy was simultaneously performed. Blood sample was collected from inferior vena cava 48 h post reperfusion. Renal function was assessed by measuring serum creatinine (SCr) levels. Expressions of inflammatory and apoptotic markers by real-time (RT)-qPCR were comparatively quantified. High-throughput RNA sequencing was applied to MSCD-7 vs. SD-7 non-ischemic right kidneys. Relevant pathways were detected using an Over-Representation Analysis with WebGestalt, and confirmed by RT-qPCR. Results: Scr levels reached 1.4 ` 0.7 vs. 2.4 ` 0.8 mg/dL in MSCD-7 vs. SD-7 group (p < 0.05). MSC infusion significantly reduced mRNA expression of Casp3, Hsp 70, Kim-1, Mcp-1 and Il-6 and increased mRNA expression of Bcl compared to saline. Among 25 908 genes, 748 were identified as significantly differentially expressed (False Discovery Rate (FDR), <0.05) between MSCD-7 and SD-7 non-ischemic kidneys. Among the most affected metabolic pathways, renal lipid metabolism was significantly altered, with down-regulation of fatty acid biosynthesis and an up-regulation of PPARa pathway in MSCD-7 vs. SD-7 groups. By immunoblotting, PPARa and phosphorylated-PPARa were significantly increased in MSCD-7 vs. SD-7 kidneys, in both non-ischemic and ischemic conditions. Moreover, levels of malondialdehyde-derived lipid peroxidation products were decreased in MSCD-7 ischemic kidneys in comparison to SD-7 ischemic kidneys. Conclusion: MSC infusion at day 7 prior injury critically impacts renal lipid metabolism, which may condition kidney parenchyma against I/R. [less ▲]

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See detailSurgical factors and not donor type per se are risk factors for acute kidney injury after liver transplantation
MEURISSE, Nicolas ULiege; Smet, Heloise ULiege; LEDOUX, Didier ULiege et al

in Transplant International (2017, September), 30(S2), 106-107298

Background: Because Liver Transplantation (LT) using DCD has been shown to be risk factor for Acute Kidney Injury (AKI), we reviewed results at our center. Patients and Methods: AKI was defined as ... [more ▼]

Background: Because Liver Transplantation (LT) using DCD has been shown to be risk factor for Acute Kidney Injury (AKI), we reviewed results at our center. Patients and Methods: AKI was defined as decrease >50% eGFR (CKD- EPI) within 48 h postreperfusion (RIFLE). 106 first LT-only [63 DBD (59%) & 43 DCD (41%)] without pre-existing renal dysfunction (eGFR>60 ml/min/1,73 m2, no renal replacement therapy) were performed from 2012 to 2016. Incidence/ risk factors for AKI were assessed. Data: mean (IQR). Results: Incidence of AKI was 33% (35/106). AKI-patients were more hospitalized before LT [9/16 (56%) vs 26/89 (29%), p < 0.01], with higher labMELD [16 (10–23) vs 12 (8–16), p = 0.01]. Donor type [11/43 DCD (25%) vs 24/63 DBD (39%), p = 0.16], donor hepatectomy time [38 min (26–50) vs 35 (25–42), p = 0.37], cold ischemic time [6 h (4.1–7.6) vs 5.1 (3.4–6.4), p = 0.21], time for anastomosis [44 min (35–49) vs 42 (38–48), p = 0.53], postreperfusion syndrome [19/46 (42%) vs 27/46 (58%), p = 0.07] were similar between AKI & non-AKI groups. AKI was more frequent if lungs were procured first in the donor [23/48 (48%) vs 11/56 (19%), p < 0.01]. Recipient surgery was longer in the AKI group [5.2 h (3.9–6.3) vs 4.3 (3.4–4.8), p < 0.01]. AKI was more frequent if platelets were transfused during LT [19/42 (56%) vs 15/59 (44%), p = 0.03]. Blood volume administrated from the cellsaver was larger in the AKI-patients [834 ml (300–750) vs 408 (0–550), p = 0.03]. AKI-patients have a higher peak AST [1235 U/L (310–1858) vs 812 (429–978), p = 0.04]. Haemoglobin [8.8 g/dl (7.4–9.9) vs 10 (8.5–11.7)] & platelets [69x103 (50 9 103–87 9 103) vs 89 9 103 (50 9 103–118 9 103)] at day 1 postreperfusion were significantly lower if AKI occurred. After multivariable analysis, thoracic procurement before liver [OR 5.75 (1.76–18.77), p = 0.004] & recipient surgery duration [OR 1.64 (1.15–2.32), p = 0.006] were only risk factors for AKI. Conclusion: Rapid donor/recipient surgery and not donor type are key factors to prevent AKI-post-LT. [less ▲]

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See detailRecycling of silicon used in solar cells to prepare silicon-carbon composite powders as anode material in li-ion batteries
Eshraghi, Nicolas ULiege; Mahmoud, Abdelfattah ULiege; Berardo, Loris ULiege et al

Poster (2017, September)

Currently, silicon (Si) coming from the recycling of solar cells is a non-valued fraction. The principal aim of this work is the development of silicon recovered during the dismantling of solar panels as ... [more ▼]

Currently, silicon (Si) coming from the recycling of solar cells is a non-valued fraction. The principal aim of this work is the development of silicon recovered during the dismantling of solar panels as an electrode material for lithium or sodium batteries. The main technological challenge associated with the use of silicon in this type of application is to control the volume expansion during charge/discharge cycles. This problem could be solved through the synthesis of Silicon/carbon composites in which the size of the silicon particles and their dispersion must be controlled [1–4]. We develop a carbon matrix consisting of graphene or carbon nanotubes (CNT) that allow the incorporation of silicon particles coated with a carbon layer (Si@C/C). The process is divided in two main steps. In the first step, Si wafer pieces are ground to prepare Si powder and then a mixed suspension of Si and an organic carbon source (Acetic acid, Ascorbic acid or Lactose) is spray-dried followed by heat treatment to generate the coverage of silicon particles with carbon (Si@C). In the second step, aqueous suspension of Si@C and graphene/CNT is spray dried and heat treated to obtain the final composite structure. The morphology of composite materials is analyzed by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). Electrochemical performance of Si@C/C composites are characterized by galvanostatic charge-discharge cycling and electrochemical impedance spectroscopy (EIS). [less ▲]

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See detailL'(ir)responsabilité du pouvoir judiciaire : fondement et mise à l'épreuve de l'immunité judiciaire en droits québécois et belge
Bouhon, Frédéric ULiege; Lacroix, Mariève

in Revue de Droit International et de Droit Comparé (2017), 2017/3

Ce long article compare les régimes juridiques belge et québécois sur la question de la responsabilité civile pour les fautes commises par les juges dans l'exercice du pouvoir judiciaire. Bien que les ... [more ▼]

Ce long article compare les régimes juridiques belge et québécois sur la question de la responsabilité civile pour les fautes commises par les juges dans l'exercice du pouvoir judiciaire. Bien que les solutions retenues de part et d’autre de l’Atlantique semblent divergentes a priori – absolutisme de l’immunité du juge au Québec et relativisation de celle-ci en Belgique –, un examen plus approfondi révèle que les incidences pratiques ne sont pas aussi radicalement opposées. Certes, l’État belge peut engager sa responsabilité civile en présence d’une faute du juge, ce qui ne saurait être admis au Québec , mais les modalités de l’action civile que la jurisprudence belge a retenues (spécialement la condition de recevabilité et la notion de faute caractérisée) limitent fortement l’ampleur du contentieux dans ce domaine. Par ailleurs, au Québec, on relève un infléchissement – purement théorique, car aucun cas concret où la responsabilité civile du juge a été retenue n’existe à l’heure actuelle – du principe de l’immunité absolue du juge dans le cadre de sa responsabilité civile personnelle, lorsqu’il agit sans compétence, tout en sachant ne pas avoir compétence d’agir ainsi. [less ▲]

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See detailPreparation and characterization of Silicon-carbon composite powders using recycled Silicon from solar cells as anode material in Li-ion batteries
Eshraghi, Nicolas ULiege; Mahmoud, Abdelfattah ULiege; Berardo, Loris ULiege et al

Poster (2017, September)

Currently, silicon (Si) coming from the recycling of solar cells is a non-valued fraction. The principal aim of this work is the development of silicon recovered during the dismantling of solar panels as ... [more ▼]

Currently, silicon (Si) coming from the recycling of solar cells is a non-valued fraction. The principal aim of this work is the development of silicon recovered during the dismantling of solar panels as electrode material for Li-ion batteries. The main technological challenge associated with the use of silicon in this type of application is to control the volume expansion during charge/discharge cycles. This drawback could be avoided through the formation of Silicon/carbon composites in which the size of the silicon particles and their dispersion must be controlled. In this research, we develop a carbon matrix consisting of graphene or carbon nanotubes (CNT) that allow the incorporation of silicon particles coated with a carbon layer (Si@C/C). The process is divided in two main steps : I) the grinding of leached Si wafer pieces in order to extract pure Si powder and then a mixed aqueous suspension of this recycled Si and an organic carbon source (Acetic acid, Ascorbic acid or Lactose) is spray-dried followed by heat treatment to generate the coating of silicon particles with carbon (Si@C). Then, II) aqueous suspension of Si@C and graphene/CNT is spray dried and calcined to obtain the final composite structure (Si@C/C). The morphology of composite materials is analyzed by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). Electrochemical performance of Si@C/C composites are characterized by galvanostatic charge-discharge cycling and electrochemical impedance spectroscopy (EIS). [less ▲]

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See detailReliability of a standardized protocol for bedside quadriceps strength measurement in critically ill patients
ROUSSEAU, Anne-Françoise ULiege; Freycenon, Gaëlle ULiege; KELLENS, Isabelle ULiege et al

in Intensive Care Medicine Experimental (2017, September), 5(S2), 327

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See detailPlantes invasives dans les carrieres europeennes : quelle est la situation ?
Monty, Arnaud ULiege; Ortmans, William; Jorion, Alexis et al

Poster (2017, September)

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See detailBio-chemical Raman imaging using targeted-SERS
Verdin, Alexandre ULiege; Malherbe, Cédric ULiege; Eppe, Gauthier ULiege et al

Poster (2017, September)

Raman and SERS spectral imaging, which consists in reconstructing a Raman intensity profile over a 2D or 3D section of a given sample (in presence or not of a nanosubstrate), allow to visualise the ... [more ▼]

Raman and SERS spectral imaging, which consists in reconstructing a Raman intensity profile over a 2D or 3D section of a given sample (in presence or not of a nanosubstrate), allow to visualise the variation of the chemical composition associated with the micro-structure of the sample. In particular, targeted-SERS imaging also enables the specific imaging of various macromolecules targeted by SERS probes in complex biological samples such as cancerous cells. To illustrate the versatility of Raman imaging, we describe two applications that were investigated recently in our laboratory. First, 3D Raman imaging was used to investigate a microcavity in a matrix of gypsum, revealing fossilised carbonaceous compounds dispersed in a filamentous shape, highly suggesting the presence of fossilised bacteria. Secondly, SERS probes were synthesised to specifically target the FRα receptor of folic acid which are often over-expressed at the surface of cancerous cells. Confocal Raman imaging was used to study the localization of the probes after incubation with KB cells (oral cancer) to confirm the specific targeting of FRα membrane receptors (Fig. 1). Moreover, our SERS probes allowed us to distinguish two different cancerous cell lines (namely KB and PC-3), based on the degree of expression of the FRα receptor of these two lines (high for KB and low for PC-3). In the future, these SERS probes may be used for distinguishing between cancerous and healthy cells since healthy cells have a lower degree of expression of FRα. [less ▲]

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See detailLa naissance de l'Etat théocratique en Iran après la révolution de 1979
Bayramzadeh, Kamal ULiege

in Wintgens, Sophie; Weerts, Audrey (Eds.) L'Etat dans tous ses états (2017)

La présente contribution se donne pour objectif de réaliser une étude sur les liens entre la révolution de 1979 en Iran et l’instauration d’un régime politique théocratique (la République islamique), afin ... [more ▼]

La présente contribution se donne pour objectif de réaliser une étude sur les liens entre la révolution de 1979 en Iran et l’instauration d’un régime politique théocratique (la République islamique), afin d’en examiner sa nature, sa structure et son fonctionnement, à savoir le mode d’organisation de l’État à travers les prismes du régime politique instauré, de sa structure socio-économique, de sa charpente juridique et de sa politique étrangère. Une telle analyse implique nécessairement que l’on se penche préalablement sur les causes et les fondements de la révolution qui, en 1979, a renversé la dynastie impériale Pahlavi pour instaurer une République islamique que l’on pourrait définir comme un système politique hybride, porteur de valeurs islamiques et républicaines qui s’inscrivent dans la Constitution nationale. La dualité du système politique entraîne un paradoxe permanent dans la société iranienne entre le pouvoir populaire et le « pouvoir divin » : une partie importante de la population ne s’identifie pas au régime politique, alors que les dirigeants du régime insistent sur la réalisation de la « volonté divine » par le principe du velâyat-e faqih, qui donne un caractère théocratique à l’État iranien. Dans cette condition, la « volonté générale » est subordonnée à la « volonté divine », car selon les tenants de ce discours, la source de la souveraineté est divine. En effet, le régime iranien est fondé sur le principe du velâyat-e faqih (tutelle de juristes théologiens) – élaboré en 1971 par Ruhollah Khomeyni1 durant son exil à Najaf en Irak – incarné par le « Guide suprême de la révolution », soit la plus haute autorité politique de l’État selon la Constitution, et prééminent par rapport au président de la République. [less ▲]

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See detailModel Order Reduction of Nonlinear Eddy Current Problems Using Missing Point Estimation
Paquay, Yannick ULiege; Bruls, Olivier ULiege; Geuzaine, Christophe ULiege

in Model Reduction of Parametrized Systems (2017)

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See detailLes "expertus du vécu". Prémices d'un renversement de perspective dans les services publics fédéraux?
Nisen, Laurent ULiege

Article for general public (2017)

Les experts du vécu constituent un dispositif original dont l'objectif est de rendre les services publics fédéraux plus accessibles aux citoyens, et plus particulièrement aux plus vulnérables d'entre eux ... [more ▼]

Les experts du vécu constituent un dispositif original dont l'objectif est de rendre les services publics fédéraux plus accessibles aux citoyens, et plus particulièrement aux plus vulnérables d'entre eux. Cet article vise à vérifier les conditions de réalisation de leur mission et s'il s'agit d'un réel progrès dans le rapprochement entre administration et usagers, voire en quoi ils peuvent, ou non, insuffler un renversement de perspective. [less ▲]

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See detailRoland Barthes et les écritures de la chronique
Stienon, Valérie ULiege

in Bertrand, Jean-Pierre (Ed.) Roland Barthes: continuités. Actes du colloque de Cerisy de juillet 2016 (2017)

La plupart des textes de Roland Barthes sont le produit d’une commande – amicale, événementielle ou éditoriale. L’inscription dans un genre ou l’investissement d’un mode d’écriture s’appuie donc sur une ... [more ▼]

La plupart des textes de Roland Barthes sont le produit d’une commande – amicale, événementielle ou éditoriale. L’inscription dans un genre ou l’investissement d’un mode d’écriture s’appuie donc sur une situation de communication dont les paramètres sont bien déterminés et qui est elle- même guidée par une demande préalable, de sorte que dispositif générique et horizon d’attente s’entre-déterminent. Plus encore, les commandes passées à Barthes, avant d’être des livres, prennent souvent la forme d’articles dans des périodiques. Ce constat rappelle la dimension intrinsèquement circonstancielle de l’écriture barthésienne, propice à la relation d’actualité. L'article examine dans quelle mesure la pratique de la chronique peut rendre compte du cheminement de pensée et d’écriture de Barthes. Il apparaît que c’est l’ensemble d’un parcours intellectuel et professionnel qui peut ainsi être passé en revue(s). [less ▲]

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