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See detailOn the Analysis of Internet Paths with DisNETPerf, a Distributed Paths Performance Analyzer
Wassermann, Sarah ULg; Casas, Pedro; Donnet, Benoît ULg et al

in Proc. 10th IEEE Workshop on Network Measurements (WNM) (2016, November)

Traceroute is the most widely used Internet path analysis tool today to study the topology of the Internet and to diagnose routing failures as well as poor performance events. A major limitation of ... [more ▼]

Traceroute is the most widely used Internet path analysis tool today to study the topology of the Internet and to diagnose routing failures as well as poor performance events. A major limitation of traceroute when the destination is not controllable by the user is its inability to measure reverse paths, i.e., the path from any given destination back to the source. This is a major drawback for ISPs, who need to understand the performance of the Internet paths connecting popular services (e.g., YouTube and Facebook) to their customers. Even if public servers and distributed measurement platforms can provide partial reverse path visibility through ad-hoc measurements, there is still a need for a structured approach capable of analyzing the performance of Internet paths connecting any pair of nodes (servers, routers, hosts, etc.). While the problem of reverse traceroute has been addressed in the past, proposed techniques rely on IP address spoofing – which might lead to security concerns, and assume the availability of certain route-tracking options –, which might not be available. In this paper, we introduce and evaluate DisNETPerf, a new tool which provides exactly the same type of information as traceroute, but for paths connecting arbitrarily selected nodes. DisNETPerf works by firstly locating probes (i.e., measurement points) that are the closest to a given target node, using them to perform traceroute measurements from the target point-of-view to a given destination for path performance monitoring and troubleshooting purposes. We propose two techniques for probe location, and demonstrate that the reverse path (from server to users) can be measured with very high accuracy in certain scenarios. We also analyze relevant characteristics of Internet paths and distributed measurement platforms, which reinforce the applicability and relevance of DisNETPerf in current Internet. [less ▲]

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See detailInstitut de droit International’s Crisis (1873-1890’)
Genin, Vincent ULg

Conference (2016, November)

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See detailEtude transfrontalière des besoins de formation en Education Thérapeutique du Patient souffrant de diabète et/ou d’obésité pour le personnel médical et paramédical : enquête par méthode du groupe nominal
Pétré, Benoît ULg; Ketterer, Frédéric ULg; Vanmeerbeek, Marc ULg et al

in Presse Médicale (2016), 45(10), 351-361

INTRODUCTION: The design of continuous training programs in therapeutic patient education (ETP) should be inspired by needs shown by the professionals concerned in terms of mobilization or acquisition of ... [more ▼]

INTRODUCTION: The design of continuous training programs in therapeutic patient education (ETP) should be inspired by needs shown by the professionals concerned in terms of mobilization or acquisition of skills in this domain. The objective of this study is to analyze needs expressed by healthcare professionals (HP) involved in patients' management presenting a type 2 diabetes (T2D) and/or obesity and to compare them with the existing recommendations. METHODS: One hundred and five PS (general practitioners, dietitians and nurses) of 3 frontier regions of French-speaking European countries (France, Belgium and Grand duchy of Luxembourg) were questioned in 12 monodisciplinary groups according to the technique of the nominal group. Needs expressed by the participants were classified in the categories of the reference table of skills to dispense TPE (National Institute for Health Prevention and Education [INPES], 2013). RESULTS/DISCUSSION: Among needs expressed by HP, 52 % of the votes targeted relational skills, 10 % of the skills relative to the biomedical techniques, 20 % of the skills relative to the educational techniques and 11 %, those of organization and the coordination. Seven percent of the proposals were out of the categories of the INPES. Results do not allow to establish profiles of skills according to the studied region or profession. The recognition of the TPE by the French legislation does not seem to influence in a major way the data. CONCLUSION: The needs expressed by PS in the context of this study are focused on the relation HP/patient that is the heart of the TPE. It would however be necessary to raise awareness among HP in the acquisition of the other skills which concern in particular the animation of group, the interprofessional coordination, the consideration of the environment or more generally the procedures. [less ▲]

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See detailThe construction of religion as a ‘public problem’. The emergence of Islam in the public space during Tunisia’s transition to democracy (2011--2014)
Nachi, Mohamed ULg

in Social Sciences Information = Information sur les Sciences Sociales (2016), 55(4),

La construction de l'islam en "problème public" au cours de la période de transition démocratique.

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See detailTransition to democracy in Tunisia. Learning about citizenship in a national and transnational context
Nachi, Mohamed ULg

in Social Sciences Information = Information sur les Sciences Sociales (2016), 55(4),

La transition en Tunisie a constitué un moment fort d'apprentissage de la démocratie.

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See detailNumerical modeling of coupled thermal-hydro-mechanical behavior of GMZ bentonite in the China-Mock-up test
Zhao, Jingbo; Chen, Liang; Collin, Frédéric ULg et al

in Engineering Geology (2016), 214

Gaomiaozi (GMZ) bentonite is currently considered as themost suitable buffermaterial for high-level radioactive waste geological repository in China. To investigate the long-term performance of GMZ ... [more ▼]

Gaomiaozi (GMZ) bentonite is currently considered as themost suitable buffermaterial for high-level radioactive waste geological repository in China. To investigate the long-term performance of GMZ bentonite under repository conditions, a large scale mock-up test has been carried out since 2011. In the test, a hydration systemand an electrical heater were employed to simulate the Thermal-Hydro-Mechanical (THM) coupled conditions near a repository. In this work, a numerical study is performed to reproduce the experimental data obtained in the first three years of the China-Mock-up experiment. The principle THM characteristics and parameters of the bentonite are presented. On this basis, a THM coupled constitutive model is introduced. With the proposed model, numerical simulations of the China-Mock-up test are carried out using LAGAMINE. The numerical data of temperature, relative humidity, and swelling pressure of the GMZ compacted bentonite are compared with the experimental ones.We discuss the effect of the balance between the drying effect and water penetration process on the THM behavior of the GMZ bentonite. The good agreement between the predicted and experimental results suggests that the proposed model can reproduce the fundamental behavior of GMZ compacted bentonite under coupled THM conditions. [less ▲]

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See detailZwischen den Zeiten - die sechste Reform des belgischen Staates aus Perspektive der Deutschsprachigen Gemeinschaft
Niessen, Christoph; Reuchamps, Min; Bouhon, Frédéric ULg

in Jahrbuch des Föderalismus 2016. Föderalismus, Subsidiarität und Regionen in Europa (2016)

L'article fait le point sur les implications de la sixième réforme de l'État pour la Communauté germanophone, ses compétences et sa place dans le système fédéral belge.

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See detailEfficient Computation of the Minimum of Shape Quality Measures on Curvilinear Finite Elements
Johnen, Amaury ULg; Geuzaine, Christophe ULg; Toulorge, Thomas et al

in Procedia Engineering (2016, November), 163

We present a method for computing robust shape quality measures defined for any order of finite elements. All type of elements are considered, including pyramids. The measures are defined as the minimum ... [more ▼]

We present a method for computing robust shape quality measures defined for any order of finite elements. All type of elements are considered, including pyramids. The measures are defined as the minimum of the pointwise quality of curved elements. The computation of the minimum, based on previous work presented by Johnen et al. (2013) [1] and [2], is very efficient. The key feature is to expand polynomial quantities into Bézier bases which allows to compute sharp bounds on the minimum of the pointwise quality measures. [less ▲]

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See detailSpectroscopie Raman: Application à l'Etude de Minéraux
Malherbe, Cédric ULg; Eppe, Gauthier ULg

Conference given outside the academic context (2016)

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See detailLiturgie, cérémonial et architecture des églises des congrégations féminines implantées en ville sur la « dorsale catholique » (XVe-XVIIIe siècles)
Piront, Julie ULg

Conference (2016, November)

Dans les églises des congrégations féminines, la problématique du « voir » est étroitement associée au « ne pas être vu ». Plus encore que leurs homologues masculins, moniales et religieuses, implantées ... [more ▼]

Dans les églises des congrégations féminines, la problématique du « voir » est étroitement associée au « ne pas être vu ». Plus encore que leurs homologues masculins, moniales et religieuses, implantées en milieu urbain tout en étant soumises à la stricte clôture, ont dû trouver des solutions architecturales qui satisfassent à ces deux exigences. Dans ce contexte, les enjeux se focalisent en particulier sur l’articulation de l’église « extérieure » et de l’église « intérieure » – pour reprendre l’expression de Carlo Borromeo – où se déroulent les principaux moments de la vie liturgique de la communauté. En examinant les églises de trois ordres méconnus implantés aux frontières de la catholicité entre le XVe et le XVIIIe siècle (chanoinesses du Saint-Sépulcre, bénédictines réformées de la Paix Notre-Dame et annonciades célestes), il s’agit d’analyser tant la forme (plan, décor, mobilier) que la fonction des nouvelles constructions, mais aussi les aménagements – bien moins connus – des églises monastiques préexistantes et des maisons particulières acquises lors de la fondation. [less ▲]

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See detailCROSSROADS novembre 2016
Sacré, Robert ULg

Diverse speeche and writing (2016)

Programme radio hebdomadaire consacré aux musiques Américaines et Africaines-Américaines ; streaming : www.equinoxefm.be ; podcasts : www.mixcloud.com/robertsacre9 ;

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See detailEntre rêve et rébus. J.J. Grandville bédéiste ?
Stienon, Valérie ULg

in Collectif (Ed.) Le Magasin du XIXe siècle (2016)

Des pionniers de la bande dessinée, les Töpffer, Cham, Bertall et autres Doré, J.J. Grandville est probablement le moins considéré. L’audace de ses mondes a pu déconcerter, l’attrait pour ses personnages ... [more ▼]

Des pionniers de la bande dessinée, les Töpffer, Cham, Bertall et autres Doré, J.J. Grandville est probablement le moins considéré. L’audace de ses mondes a pu déconcerter, l’attrait pour ses personnages zoomorphes a occulté ses autres réalisations. Son univers graphique n’en a pas moins approché l’art séquentiel naissant. [less ▲]

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See detailA Novel Physiological Glycosaminoglycan-Deficient Splice Variant of Neuropilin-1 Is Anti-Tumorigenic In Vitro and In Vivo
Hendricks, Céline; Dubail, Johanne; Brohée, Laura ULg et al

in PLoS ONE (2016)

Neuropilin-1 (NRP1) is a transmembrane protein acting as a co-receptor for several growth factors and interacting with other proteins such as integrins and plexins/semaphorins. It is involved in axonal ... [more ▼]

Neuropilin-1 (NRP1) is a transmembrane protein acting as a co-receptor for several growth factors and interacting with other proteins such as integrins and plexins/semaphorins. It is involved in axonal development, angiogenesis and cancer progression. Its primary mRNA is subjected to alternative splicing mechanisms generating different isoforms, some of which lack the transmembrane domain and display antagonist properties to NRP1 full size (FS). NRP1 is further post-translationally modified by the addition of glycosaminoglycans (GAG) side chains through an O-glycosylation site at serine612. Here, we characterized a novel splice variant which has never been investigated, NRP1-Δ7, differing from the NRP1-FS by a deletion of 7 amino acids occurring two residues downstream of the O-glycosylation site. This short sequence contains two aspartic residues critical for efficient glycosylation. As expected, the high molecular weight products appearing as a smear in SDS-PAGE and reflecting the presence of GAG in NRP1-FS were undetectable in the NRP1-Δ7 protein. NRP1-Δ7 mRNA was found expressed at an appreciable level, between 10 and 30% of the total NRP1, by various cells lines and tissues from human and murine origin. To investigate the biological properties of this isoform, we generated prostatic (PC3) and breast (MDA-MB-231) cancer cells able to express recombinant NRP1-FS or NRP1-Δ7 in a doxycycline-inducible manner. Cells with increased expression of NRP1-Δ7 were characterized in vitro by a significant reduction of proliferation, migration and anchorage-independent growth, while NRP1-FS had the expected opposite “pro-tumoral” effects. Upon VEGF-A165 treatment, a lower internalization rate was observed for NRP1-Δ7 than for NRP1-FS. Finally, we showed that NRP1-Δ7 inhibited growth of prostatic tumors and their vascularization in vivo. This report identifies NRP1-Δ7 as a splice variant displaying anti-tumorigenic properties in vitro and in vivo, emphasizing the need to consider this isoform in future studies. [less ▲]

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See detailIncidence and Phenotype at Diagnosis of Very-early-onset Compared with Later-onset Paediatric Inflammatory Bowel Disease: A Population-based Study [1988-2011].
Bequet, Emeline ULg; Sarter, Hélène; Fumery, Mathurin et al

in Journal of Crohn's and Colitis [=JCC] (2016)

Detailed reference viewed: 16 (1 ULg)
See detail"Madame Bovary c'est moi"
Cormann, Grégory ULg

Conference (2016, October 29)

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See detailApplication of rep-PCR as molecular typing method for dermatophytes
SACHELI, Rosalie ULg; ADJETEY BAHUN, Akolé ULg; DARFOUF, Rajae ULg et al

Conference (2016, October 29)

Background The distinction of dermatophytes strains by conventional methods is problematic due to a lack of reliable characteristics between isolates. The ability to identify individual organisms allows ... [more ▼]

Background The distinction of dermatophytes strains by conventional methods is problematic due to a lack of reliable characteristics between isolates. The ability to identify individual organisms allows identification of infection sources, such as communal swimming and public washing rooms and apply appropriate control measures. Several outbreaks of dermatophytes infection have already been described in Europe and the feasibility of comparing DNA fingerprints is of interest in this particular field. We have successfully applied the rep-PCR method for typing dermatophytes species such as Microsporum audouinii, Trichophyton violaceum and Trichophyton mentagrophytes complex (T.mentagrophytes complex). Methods The Diversilab® system (bioMérieux, France) has been used to perform rep-PCR. Strains of M. audouinii (116) and T. violaceum (23) were collected during a national survey conducted by the National Reference center (NRC) for mycoses (Liège) in Belgium from February 2013 to March 2014. Strains of T. mentagrophytes complex (32) are part of the national collection of the NRC collected between 2012 and 2015. Results The Diversilab® is able to distinguish different subspecies between the same species complex as it was confirmed with the T. mentagrophytes complex. For this group of strains, two major groups are clearly visible after Diversilab analysis and correspond to white strains (ITS sequenced as T. interdigitale) and yellow strains (ITS sequenced as A. benhamiae) of T. mentagrophytes complex. Both groups share only 70% of similarity. Within a same species of dermatophyte, the Rep-PCR is also able to define several subgroups sometimes linked with epidemiological factors. Inside the T. violaceum strains circulating in Belgium, two different DNA fingerprints have been found. These two subgroups were well separated regarding the geographical location in Belgium (Wallonia and Flanders). Inside the M. audouinii species, 6 different DNA fingerprints have been detected with a main group. The degree of similarity between these six groups is comprised between 85,6% and 94%. Strains belonging to the six groups were defined as M. audouinii by ITS sequencing. Conclusion The DiversiLab® system with the Rep-PCR technology proved to be an efficient method for dermatophytes molecular typing. It is highly sensitive to discriminate small genotypic variation between two strains within the same species which is not possible with other molecular methods such as ITS sequencing. Inside the T. mentagrophytes complex, it permits to easily distinguish the yellow zoophilic strains from the white anthropophilic strain, hardly possible by microscopy. [less ▲]

Detailed reference viewed: 17 (8 ULg)