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See detailBiochemical characterisation of the seed oils of four safflower (Carthamus tinctorius) varieties grown in north-eastern of Morocco
Ben Moumen, Abdessamad; Mansouri, Farid; Richard, Gaetan ULg et al

in International Journal of Food Science & Technology (2015)

The quality of the oil of four safflower varieties, originating from Spain (Rancho), India (Sharda) and Morocco (Cartamar and Cartafri), which were cultivated at the experimental station in Oujda (a semi ... [more ▼]

The quality of the oil of four safflower varieties, originating from Spain (Rancho), India (Sharda) and Morocco (Cartamar and Cartafri), which were cultivated at the experimental station in Oujda (a semi-arid region of eastern Morocco) was evaluated through analysis of their phenolic and carotenoid contents. The composition of the phenolic compounds of safflower oil has not yet been documented. Therefore, in this preliminary study, Thirty different phenolic compounds were identified, and significant differences between the oil varieties were observed (P < 0.05). In the seed oil from the Rancho and Sharda safflower varieties, the main phenolic compound was trans-chalcone, representing 13.45% and 11.8%, respectively, of the total phenolics, whereas in Cartamar and Cartafri oils, naringin accounted for 26.82% and 16.5%, respectively, of the total phenolics. The total carotenoid contents ranged from 1.13 mg/kg (Rancho) to 1.34 mg/kg (Cartamar and Cartafri).We observed that b-cryptoxanthin (0.31–0.37 mg/kg) and b-carotene (0.3–0.35 mg/kg) were the predominant carotenoids in all of the safflower oils that were studied. [less ▲]

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See detailL'évaluation émancipatrice, l'évaluateur et les formes de la communauté
Absil, Gaëtan ULg; Vandoorne, Chantal ULg

in L'Observatoire (2015), 82(Janvier-Février-Mars 2015), 30-35

Cet article explore des enjeux de l’évaluation émancipatrice d’un projet de santé communautaire, d’un programme transfrontalier de promotion de la santé mentale et de projets de promotion de la santé par ... [more ▼]

Cet article explore des enjeux de l’évaluation émancipatrice d’un projet de santé communautaire, d’un programme transfrontalier de promotion de la santé mentale et de projets de promotion de la santé par les services de santé scolaire. Ces enjeux sont questionnés selon les axes politique, opérationnel ou constructiviste de l’évaluation. Le propos porte sur les liens entre l’évaluation émancipatrice et la communauté formée par les stakeholders. Il ouvre une réflexion sur les enjeux micro, méso et macro sociaux de l’évaluation et la posture de l’évaluateur. [less ▲]

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See detailA review of gliptins for 2014.
Scheen, André ULg

in Expert opinion on pharmacotherapy (2015), 16(1), 43-62

Introduction: Dipeptidyl peptidase-4 (DPP-4) inhibitors (gliptins) occupy an increasing place in the armamentarium of drugs used for the management of hyperglycaemia and offer new opportunities for a ... [more ▼]

Introduction: Dipeptidyl peptidase-4 (DPP-4) inhibitors (gliptins) occupy an increasing place in the armamentarium of drugs used for the management of hyperglycaemia and offer new opportunities for a personalized medicine in patients with Type 2 diabetes. Areas covered: An updated review providing an analysis of available recent data with commercialized DPP-4 inhibitors, with a special focus on: differences between the various molecules, novelties regarding their mechanism of action, clinical efficacy in mono- and various combined therapies, comparison with other new therapies, efficacy-safety profile in at risk patients, concern about pancreatic safety, perspectives in cardiovascular prevention and, finally, a selection of remaining unanswered important questions for the clinician. Expert opinion: DPP-4 inhibitors offer various advantages when compared to other glucose-lowering agents. Despite they have been commercialized since a few years only, available data obtained in randomised controlled trials are of better quality compared to those available with ancient classical glucose-lowering agents, especially in more fragile populations such as elderly people, individuals with renal impairment or at high cardiovascular risk and patients at higher risk of hypoglycaemia. However, there remain uncertainties and controversies that should be resolved by further ongoing large prospective controlled trials and increasing clinical experience combined with a careful post-marketing surveillance. [less ▲]

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See detailCROSSROADS le magazine sonore des musiques africaines-américaines
Sacré, Robert ULg

Diverse speeche and writing (2015)

Programme radio hebdomadaire consacré aux musiques africaines-américaines ; FM 100.1 ; streaming : www.equinoxefm.be ; podcast : www.mixcloud.com/robertsacre9

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See detailCase study at Attapeu: chicken model
Andres, Ludovic ULg

Learning material (2015)

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See detailCamorra in Montesacro. Urban and social transformation in a southern Italian community
De Biase, Marco ULg

in ECPR Standing Group on Organised Crime (2015), 12(1), 8-10

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See detailThe impact of oregano (Origanum heracleoticum) essential oil and carvacrol on virulence gene transcription by Escherichia coli O157:H7
Mith, Hasika; Clinquart, Antoine ULg; Zhiri, Abdesselam et al

in FEMS Microbiology Letters (2015), 362

The aim of the current study was to determine, via reverse transcription quantitative polymerase chain reaction (RT-qPCR) analysis, the effect of oregano essential oil (Origanum heracleoticum) and ... [more ▼]

The aim of the current study was to determine, via reverse transcription quantitative polymerase chain reaction (RT-qPCR) analysis, the effect of oregano essential oil (Origanum heracleoticum) and carvacrol, its major component, on the expression of virulence-associated genes in enterohaemorrhagic Escherichia coli (EHEC) O157:H7 ATCC strain 35150. Both oregano oil and carvacrol demonstrated their efficacy firstly, by inhibiting the transcription of the ler gene involved in up regulation of the LEE2, LEE3 and LEE4 promoters and of attaching and effacing lesions and secondly by decreasing both Shiga toxin and fliC genes expression. In addition, a decrease in luxS gene transcription involved in quorum sensing was observed. These results were dose dependent and showed a specific effect of O. heracleoticum and carvacrol in downregulating the expression of virulence genes in EHEC O157:H7. These findings suggest that oregano oil and carvacrol have the potential to mitigate the adverse health effects caused by virulence gene expression in EHEC O157: [less ▲]

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See detailCrystallisation-driven self-assembly of poly(2-isopropyl-2- oxazoline)-block-poly(2-methyl-2-oxazoline) above the LCST
Legros, Camille ULg; De Pauw-Gillet, Marie-Claire ULg; Tam, Kam Chiu et al

in Soft Matter (2015)

The solution behaviour in water of a polyoxazoline-type block copolymer, namely poly(2- isopropyl-2-oxazoline)-block-poly(2-methyl-2-oxazoline), denoted as P(iPrOx-b-MeOx), above the lower critical ... [more ▼]

The solution behaviour in water of a polyoxazoline-type block copolymer, namely poly(2- isopropyl-2-oxazoline)-block-poly(2-methyl-2-oxazoline), denoted as P(iPrOx-b-MeOx), above the lower critical solution temperature (LCST) of the PiPrOx block was exploited to induce a temporary or permanent self-assembly. Spherical micelles were first obtained and could be disassembled in a reversible manner when kept for a short period of time (i.e. t < 1h30) above the LCST, and cooled down to room temperature. In contrast, annealing the copolymer solution for more than 1h30 at 65 °C induced the crystallisation of the PiPrOx block, as evidenced by wide angle X-ray scattering (WAXS) experiments. This crystallisationdriven self-assembly phenomenon resulted in different morphologies, including spherical and distorted crystallised micelles and micron-size fibers, their relative proportion varying with annealing time. Formation of micron-size range fiber-like structures might be explained by a re-organization of parent crystallised micelles. The crystal structure, as determined by WAXS, appeared to be identical to that of the PiPrOx homopolymer. [less ▲]

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See detailUsing local second gradient model and shear strain localisation to model the excavation damaged zone in unsaturated claystone
Pardoen, Benoît ULg; Levasseur, Séverine ULg; Collin, Frédéric ULg

in Rock Mechanics & Rock Engineering (2015), 48(2), 691-714

The drilling of galleries induces damage propagation in the surrounding medium and creates, around them, the excavation damaged zone (EDZ). The prediction of the extension and fracture structure of this ... [more ▼]

The drilling of galleries induces damage propagation in the surrounding medium and creates, around them, the excavation damaged zone (EDZ). The prediction of the extension and fracture structure of this zone remains a major issue, especially in the context of underground nuclear waste storage. Experimental studies on geomaterials indicate that localised deformation in shear band mode usually appears prior to fractures. Thus, the excavation damaged zone can be modelled by considering the development of shear strain localisation bands. In the classical finite element framework, strain localisation suffers a mesh-dependency problem. Therefore, an enhanced model with a regularisation method is required to correctly model the strain localisation behaviour. Among the existing methods, we choose the coupled local second gradient model. We extend it to unsaturated conditions and we include the solid grain compressibility. Furthermore, air ventilation inside underground galleries engenders a rock– atmosphere interaction that could influence the damaged zone. This interaction has to be investigated in order to predict the damaged zone behaviour. Finally, a hydromechanical modelling of a gallery excavation in claystone is presented and leads to a fairly good representation of the EDZ. The main objectives of this study are to model the fractures by considering shear strain localisation bands, and to investigate if an isotropic model accurately reproduces the in situ measurements. The numerical results provide information about the damaged zone extension, structure and behaviour that are in very good agreement with in situ measurements and observations. For instance, the strain localisation bands that develop in chevron pattern during the excavation and rock desaturation, due to air ventilation, are observed close to the gallery. [less ▲]

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See detailThe Tax Disputes and Litigation Review - Belgium
Docclo, Caroline ULg

in Whitehead, Simon (Ed.) The Tax Disputes and Litigation Review (2015)

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See detailThe emergence of metabolomics as a key discipline in the drug discovery process
Fillet, Marianne ULg; Frederich, Michel ULg

in Drug Discovery Today: Technologies (2015)

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See detailConfusion des codes graphiques dans les papyrus latins
Rochette, Bruno ULg; Macedo, Gabriel ULg

in Capasso, Mario; De Nonno, Mario (Eds.) Miscellanea di studi in onore di Paolo Radiciotti (2015)

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See detailA new species of Groenlandaspis Heintz, 1932 (Placodermi, Arthrodira) from the Famennian (Late Devonian) of Belgium
Olive, Sébastien ULg; Prestianni, Cyrille; Dupret, Vincent

in Journal of Vertebrate Paleontology (2015), 35(5),

A new species of the phlyctaeniid arthrodire genus Groenlandaspis from the upper Famennian of Belgium is described. The remains of Groenlandaspis potyi sp. nov. consist of dissociated thoracic armor ... [more ▼]

A new species of the phlyctaeniid arthrodire genus Groenlandaspis from the upper Famennian of Belgium is described. The remains of Groenlandaspis potyi sp. nov. consist of dissociated thoracic armor elements, but the specimen designed to be the holotype displays the median dorsal, anterior and posterior dorsolateral plates in connection. Though incomplete, the new species is characterized by an equilateral triangle-shaped median dorsal plate, a protruding posterodorsal apron of the posterior dorsolateral plate behind the overlap area for the median dorsal plate, and an overall lack of ornamentation. Groenlandaspis potyi sp. nov. constitutes the second occurrence of a Groenlandaspis species in continental Europe after the description of Groenlandaspis thorezi from upper Famennian quarries of Belgium. Another probable new species of Groenlandaspis is also described, though of unknown locality and horizon; it can however be deduced from the upper Famennian of Belgium without more precision. Together with some unpublished material of groenlandaspidids from the Famennian tetrapod-bearing locality of Strud, this material highlights the richness of the Groenlandaspididae diversity in Belgium. The discovery of Groenlandaspis potyi sp. nov. in Belgium reinforces the Famennian global distribution of this widespread genus during this period. Also, since those organisms have possibly been considered as non-marine indicators, this material is another argument pleading for close relationships between Euramerica and Gondwana around the Frasnian-Famennian boundary. [less ▲]

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See detailElsvier, Computers in Industry, Special Issue on Natural Language Processing and Text Analytics in Industry
Ittoo, Ashwin ULg; Bosh, v.d., Antal; Nguyen, Le Minh

Book published by Elsevier (2015)

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See detail"Des muets qui veulent parler". Lectures politiques, des Temps Modernes à L'Idiot de la famille
Cormann, Grégory ULg

in Bolmain, Thomas; Cormann, Grégory (Eds.) Politiques de la littérature. Bourdieu, Sartre, Foucault (2015)

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See detailBrasser l’histoire de l’art de ses larges bras : l’imagier, l’atlas, le musée imaginaire A partir de L’Atelier infini de Jean-Christophe Bailly
Hagelstein, Maud ULg

Scientific conference (2015)

Abstract : Le terrain de recherche qui m’occupe est celui de l’iconologie, aussi bien dans ses moments inauguraux (chez Warburg et Panofsky), que dans sa reprise critique au sein de la théorie de l’image ... [more ▼]

Abstract : Le terrain de recherche qui m’occupe est celui de l’iconologie, aussi bien dans ses moments inauguraux (chez Warburg et Panofsky), que dans sa reprise critique au sein de la théorie de l’image actuelle. Le pari que je voudrais faire ici – sans trop de violence, j’espère – est par conséquent celui-ci : avec L’Atelier infini, J.-C. Bailly nous emmène sur le terrain problématique de l’iconologie. En même temps, l’hypothèse n’est pas trop risquée puisqu’on peut assez facilement dégager des affinités entre Bailly et l’iconologie2. Comme d’autres théoriciens actuels (Boehm, Mitchell, Didi-Huberman), il trace des perspectives radicalement nouvelles pour la méthode d’interprétation des images dynamisée et instituée par Warburg et Panofsky, contribuant de la sorte à son actualisation critique dans les débats de la théorie de l’image contemporaine. Il m’a permis en tout cas d’assouplir un peu quelques rigidités que l’on observe très souvent dans ces débats (et sans doute aussi quelques rigidités de ma propre pensée). [less ▲]

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See detailThe Innate Immune Response of Equine Bronchial Epithelial Cells is Altered by Training
Frellstedt, Linda ULg; Gosset, Philippe; Kervoaze, Gwenola et al

in Veterinary Research (2015), 46(3), 1-12

Respiratory diseases, including inflammatory airway disease (IAD), viral and bacterial infections, are common problems in exercising horses. The airway epithelium constitutes a major physical barrier ... [more ▼]

Respiratory diseases, including inflammatory airway disease (IAD), viral and bacterial infections, are common problems in exercising horses. The airway epithelium constitutes a major physical barrier against airborne infections and plays an essential role in the lung innate immune response mainly through toll-like receptor (TLR) activation. The aim of this study was to develop a model for the culture of equine bronchial epithelial cells (EBEC) in vitro and to explore EBEC innate immune responses in trained horses. Bronchial epithelial biopsies were taken from 6 adult horses during lower airway endoscopy. EBEC were grown in vitro by an explant method. The innate immune response of EBEC was evaluated in vitro by treatment with TLR ligands. TLR3 is the most strongly expressed TLR at the mRNA level in EBEC and stimulation of EBEC with Poly(I:C), an analog of viral dsRNA, triggers a strong secretion of IFN-β, TNF-α, IL-6 and CXCL8. We further evaluated the EBEC innate immune response in horses that underwent a 4-month-training program. While training had no effect on TLR mRNA expression in EBEC as well as in bronchial biopsies, it increased the production of IFN-β after stimulation with a TLR3 ligand and decreased the secretion of TNF-α and IL-6 after stimulation with a TLR2 and TLR3 ligand. These findings may be implicated in the increased risk for viral and bacterial infections observed in sport horses. Altogether, we report a successful model for the culture of EBEC that can be applied to the investigation of pathophysiologic conditions in longitudinal studies. [less ▲]

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