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See detailRegional organizations, international norms and global governance of culture: The EU foreign policy and the diversity of cultural expressions
Vlassis, Antonios ULg

Conference (2015, February 19)

Abstract: The aim of this paper is to explore empirically and qualitatively the links between regional organizations and international norms, by using an institutionalism centered on the actors. It seeks ... [more ▼]

Abstract: The aim of this paper is to explore empirically and qualitatively the links between regional organizations and international norms, by using an institutionalism centered on the actors. It seeks thus to analyze the European Union (EU)’s capacity to act within the global governance of culture, and in particular its ability to promote the Convention on diversity of cultural expressions (CDCE) beyond the EU. What is at issue is of why and how the EU foreign cultural policy (EUFCP) uses the CDCE and its normative framework, of what purposes as well as of how the CDCE influences the EUFCP and its objectives. I argue that the CDCE offers an opportunity for the European Commission to establish itself as a foreign policy actor in cultural affairs. Nevertheless, I point out that the disconnect between the Commission and the EU culture organizations is a serious constraint for the effectiveness of the EUFCP, highlighting that the promotion of the CDCE has been especially instrumental in consolidating the Commission’s actorness in external cultural affairs. And finally, I conclude that not only the Commission’s practices largely rely on the willingness of some member states with strong interests in the cultural area, but also the EU’s interpretations on the scope and the goals of the CDCE are far from convergent. Consequently, the Commission’s ability to be a EUFCP’s agent clearly depends on the sensitiveness of the issue and the EU’s actorness is strongly linked to the context in which the EUFCP is made. [less ▲]

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See detailLes Grecs ont-ils étudié le latin dans l'Antiquité ? Quelques témoignges datant du Haut-Empire
Rochette, Bruno ULg

Scientific conference (2015, February 19)

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See detailLa question de l'acceptabilité sociale dans des projets du SPIRAL
Delvenne, Pierre ULg; Parotte, Céline ULg; Rossignol, Nicolas ULg et al

Scientific conference (2015, February 19)

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See detailDynamic Input Conductances Shape Neuronal Spiking
Drion, Guillaume ULg; Franci, Alessio ULg; Dethier, Julie ULg et al

in eNeuro (2015)

Assessing the role of biophysical parameter variations in neuronal activity is critical to the understanding of modulation, robustness and homeostasis of neuronal signaling. The paper proposes that this ... [more ▼]

Assessing the role of biophysical parameter variations in neuronal activity is critical to the understanding of modulation, robustness and homeostasis of neuronal signaling. The paper proposes that this question can be addressed through the analysis of dynamic input conductances. Those voltage-dependent curves aggregate the concomitant activity of all ion channels in distinct timescales. They are shown to shape the current-voltage dynamical relationships that determine neuronal spiking. We propose an experimental protocol to measure dynamic input conductances in neurons. In addition, we provide a computational method to extract dynamic input conductances from arbitrary conductance-based models and to analyze their sensitivity to arbitrary parameters. We illustrate the relevance of the proposed approach for modulation, compensation and robustness studies in a published neuron model based on data of the stomatogastric ganglion of the crab Cancer borealis. [less ▲]

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See detailDUSP3 Phosphatase Deficiency or Inhibition Limit Platelet Activation and Arterial Thrombosis
Musumeci, Lucia ULg; Kuijpers, Marijke; Gilio, Karen et al

in Circulation (2015), 131(7), 656-68

Background A limitation of current antiplatelet therapies is their inability to separate thrombotic events from bleeding occurrences. Better understanding of the molecular mechanisms leading to platelet ... [more ▼]

Background A limitation of current antiplatelet therapies is their inability to separate thrombotic events from bleeding occurrences. Better understanding of the molecular mechanisms leading to platelet activation is of importance for the development of improved therapies. Recently, protein tyrosine phosphatases (PTPs) have emerged as critical regulators of platelet function. Methods and Results This is the first report implicating the dual-specificity phosphatase 3 (DUSP3) in platelet signaling and thrombosis. This phosphatase is highly expressed in human and mouse platelets. Platelets from DUSP3-deficient mice displayed a selective impairment of aggregation and granule secretion mediated through the collagen receptor glycoprotein VI (GPVI) and the C-type lectin-like receptor 2 (CLEC-2). DUSP3-deficient mice were more resistant to collagen- and epinephrine-induced thromboembolism, compared to wild-type mice, and showed severely impaired thrombus formation upon ferric chloride-induced carotid artery injury. Intriguingly, bleeding times were not altered in DUSP3-deficient mice. At the molecular level, DUSP3 deficiency impaired Syk tyrosine phosphorylation, subsequently reducing phosphorylation of PLCγ2 and calcium fluxes. To investigate DUSP3 function in human platelets, a novel small-molecule inhibitor of DUSP3 was developed. This compound specifically inhibited collagen and CLEC-2-induced human platelet aggregation, thereby phenocopying the effect of DUSP3 deficiency in murine cells. Conclusions DUSP3 plays a selective and essential role in collagen- and CLEC-2-mediated platelet activation and thrombus formation in vivo. Inhibition of DUSP3 may prove therapeutic for arterial thrombosis. This is the first time a PTP, implicated in platelet signaling, has been targeted with a small-molecule drug. [less ▲]

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See detailTypus melancholicus et recommandations pratiques
Ramackers, Amélia; Englebert, Jérôme ULg

Scientific conference (2015, February 16)

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See detailFermentation du kivuguto, lait traditionnel du Rwanda: mise au point d’un starter lactique
Karenzi, Eugène ULg

Doctoral thesis (2015)

Résumé Une recherche pour la production industrielle du kivuguto, lait caillé traditionnel du Rwanda a été entreprise par la sélection de micro-organismes responsables de la fermentation de ce lait ... [more ▼]

Résumé Une recherche pour la production industrielle du kivuguto, lait caillé traditionnel du Rwanda a été entreprise par la sélection de micro-organismes responsables de la fermentation de ce lait normalement produit artisanalement. Pour ce faire, il fallait une mise au point d’un starter lactique à partir des isolats issus des échantillons de lait artisanal kivuguto. Au terme de quatre échantillonnages, un dénombrement, un isolement et une purification ont abouti à conserver dans la Collection du CWBI 390 souches pures. Par des analyses phénotypiques (microscopiques, biochimiques), associées à des tests de résistance aux conditions extrêmes et à une analyse préliminaire des propriétés technologiques, 7 souches ont été pré-sélectionnées pour la poursuite du screening. Une caractérisation moléculaire par la méthode de 16S ADNr associé ou non à l’ITS 16S-23S ADNr a assimilé ces souches à deux Lactococcus lactis, deux Leuconostoc mesenteroides et trois Leuconostoc pseudomesenteroides. Des essais de formulation de laits fermentés par des mélanges de souches et leur conservation pendant 24 jours ont permis de formuler un lait fermenté semblable au lait artisanal kivuguto par l’association d’un Lactococcus lactis, d’un Leuconostoc mesenteroides et d’un Leuconostoc pseudomesenteroides. En effet, lors d’une analyse sensorielle discriminative, un jury de dégustation constitué de huit personnes est parvenu à identifier ce lait formulé parmi deux autres laits fermentés commercialisés aussi sur le marché à des différences significatives de p=0.05 dans une première série et p=0.01 dans une deuxième série. Des analyses technologiques proprement dites ont montré que ce lait formulé fermente après 14 heures avec une acidification de 73°D à pH4.6 et à 19°C, présente des caractéristiques d’un fluide visco-élastique. Son activité protéolytique est moyenne pour ne pas développer des peptides responsables de l’amertume en stockage. Son profil aromatique comporte cinq composés principaux 3-méthylbutan-1-ol, pentan-1-ol, acide acétique, furanméthan-2-ol et furan-2(5)H-one clairement identifiés par GC-MS. L’étude de la production et de la conservation de trois souches sélectionnées a montré une bonne stabilité sur trois mois à 4°C avec des viabilités cellulaires >90%, mais moins bonne à 20°C. [less ▲]

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See detailUltraviolet observations of the atmospheres of Venus and Mars and implications for their dynamics
Stiepen, Arnaud ULg

Scientific conference (2015, February 15)

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See detailMéthodologie et analyse des politiques publiques (pratique): "chercheurs en herbe"
Parotte, Céline ULg

Learning material (2015)

Cette présentation donnée dans le cadre du cours IFRES a pour objectif de présenter le cours de méthodes et analyse des politiques publiques dispensés aux étudiants de deuxième année de baccalauréat en ... [more ▼]

Cette présentation donnée dans le cadre du cours IFRES a pour objectif de présenter le cours de méthodes et analyse des politiques publiques dispensés aux étudiants de deuxième année de baccalauréat en sciences politiques par les Professeurs Madame François et Madame Fallon. [less ▲]

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See detailAdoption by gay and lesbian parents: a cross-nationale study
Messina, Roberta ULg; D'Amore, Salvatore ULg; Green, Robert-J

Poster (2015, February 13)

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See detailL'idéologie comme norme. Althusser face au problème de la production des sujets.
Mancuso, Eva ULg

Scientific conference (2015, February 13)

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See detailEntre national et local: Louis Jacquinot, archétype du notable modéré
Bour, Julie ULg

Doctoral thesis (2015)

Louis Jacquinot was born in Gondrecourt-le-Château, a common South Meuse in 1898 and died in 1993 in Paris. It remains an unknown figure in the political history. However, it exercises governmental ... [more ▼]

Louis Jacquinot was born in Gondrecourt-le-Château, a common South Meuse in 1898 and died in 1993 in Paris. It remains an unknown figure in the political history. However, it exercises governmental functions under the Third Republic and became a minister under the Fourth and the Fifth Republic. In total, Louis Jacquinot is minister almost twenty times, including Minister of Marine (1943-1945 and 1947), Veterans Affairs (1949-1951), or Overseas (from 1951 to 1954 and 1961 1966). In parallel, the local quarry is important: MP for Meuse from 1932 to 1973, conseiller général and président du Conseil général de la Meuse from 1945 to 1973. The career of this moderate is placed under the sign of longevity. This thesis traces his life, his career and his local and national career. But this biography is devoted to the study and analysis of the recommendation of the elected job. Indeed, the Meuse MP archives contain 17 000 letters of recommendations that support this work. A general analysis of the practice in the department for nearly a century is realized through other sources of archival Meuse elected, including its predecessors (Raymond Poincaré, Jules Develle, André Maginot) and his successors (Jean Bernard). [less ▲]

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See detailSexualité, conduites à risque et timing pubertaire
Glowacz, Fabienne ULg

Scientific conference (2015, February 13)

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See detailFrom psychometric research to implementation and back: selected examples
Magis, David ULg

Conference (2015, February 13)

Current psychometric research is most often supported by computer software. New research perspectives often imply intensive simulation studies to validate the tested theories or hypotheses, and therefore ... [more ▼]

Current psychometric research is most often supported by computer software. New research perspectives often imply intensive simulation studies to validate the tested theories or hypotheses, and therefore require accurate implementation as e.g., R packages. However, it may happen that unexpected psychometric phenomena are detected almost accidentally, through such implementations with basically totally different purposes. This talk will illustrate this phenomenon by means of two recent examples from item response theory (IRT) with polytomous models: (a) the equivalence between the weighted likelihood estimator (WLE) and the Bayes modal estimator with Jeffreys prior, and (b) the relationships between observed and expected information functions. Rather than focusing on the technical details, the purpose of this talk is to highlight how the results were identified first through R implementation, then confirmed by theoretical derivations. The talk concludes by advocating for flexible and stable open-source implementations (such as R packages) to support current and ongoing psychometric research. [less ▲]

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See detailA flux extraction device to measure the magnetic moment of large samples; application to bulk superconductors
Egan, Raphael ULg; Philippe, Matthieu ULg; Wera, Laurent ULg et al

in Review of Scientific Instruments (2015), 86(2), 025107

We report the design and construction of a flux extraction device to measure the DC magnetic moment of large samples (i.e., several cm3) at cryogenic temperature. The signal is constructed by integrating ... [more ▼]

We report the design and construction of a flux extraction device to measure the DC magnetic moment of large samples (i.e., several cm3) at cryogenic temperature. The signal is constructed by integrating the electromotive force generated by two coils wound in series-opposition that move around the sample. We show that an octupole expansion of the magnetic vector potential can be used conveniently to treat near-field effects for this geometrical configuration. The resulting expansion is tested for the case of a large, permanently magnetized, type-II superconducting sample. The dimensions of the sensing coils are determined in such a way that the measurement is influenced by the dipole magnetic moment of the sample and not by moments of higher order, within user-determined upper bounds. The device, which is able to measure magnetic moments in excess of 1 Am2 (1000 emu), is validated by (i) a direct calibration experiment using a small coil driven by a known current and (ii) by comparison with the results of numerical calculations obtained previously using a flux measurement technique. The sensitivity of the device is demonstrated by the measurement of flux-creep relaxation of the magnetization in a large bulk superconductor sample at liquid nitrogen temperature (77 K). [less ▲]

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See detailVie et technique. Canguilhem et Simondon lecteurs de la Critique de la faculté de juger
Pieron, Julien ULg

Scientific conference (2015, February 13)

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See detailAn Alternative to Semantics?
Gauvry, Charlotte ULg

Conference (2015, February 12)

Detailed reference viewed: 4 (1 ULg)