Determination of chloramphenicol in honey, 1 shrimp and poultry meat with liquid chromatography-mass spectrometry. Validation of the method according to Commission Decision 2002/657/EC

in Food Analytical Methods (in press)

Chloramphenicol (CAP) is an antibiotic used for the treatment of bacterial infections in human and veterinary medicine. The use of CAP was prohibited in the European Union in 1994. Control laboratories ... [more ▼]

Chloramphenicol (CAP) is an antibiotic used for the treatment of bacterial infections in human and veterinary medicine. The use of CAP was prohibited in the European Union in 1994. Control laboratories are required to use suitably validated analytical methods to check sample compliance with the regulation. A quantitative method based on liquid chromatography coupled to isotopic dilution tandem mass spectrometry (LC–IDMS/MS) was developed for the determination of chloramphenicol in honey, shrimp and poultry meat. The experimental protocol consisted of a liquid-liquid extraction with ethyl acetate. Separation and detection were realized respectively by a 2690 Waters HPLC (Milford, MA, USA) and a Micromass Triple Quadrupole mass spectrometer (Micromass, Manchester, UK), equipped with an Electrospray source. The effects of mobile phase additives on the response of LC/ESI/MS were examined. Two different HPLC columns were tested: the X-Terra from Waters and the Alltima HP C18 HL from Alltech (Deerfield, IL, USA). A validation of the method was conducted according to the EU criteria for the analysis of chloramphenicol in foods. The decision limits (CCα) were 0.04, 0.03, 0.07 µg kg-1 and the detection capabilities (CCβ) were 0.05, 0.04, 0.08 µg kg-1 for honey, shrimp and poultry meat respectively. Those values are below the minimum required performance limit (MRPL) set at 0.3 µg kg-1 by the EU and 0.1 µg kg-1 by Belgium. Our protocol has the advantage to propose a unique extraction method working as well for honey, shrimp and poultry meat, contrary to similar published methods in which a different extraction method is used for each type of matrix. [less ▲]

L'antipsychologisme de Brentano

in Gyemant, Maria (Ed.) Psychologie et psychologisme (in press)

Variability of new bone mineral metabolism markers in patients treated with maintenance hemodialysis: implications for clinical decision making

in American Journal of Kidney Diseases (in press)

Fin de siècle/Jahrhundertwende: Eine Tendenzgeschichte

in Roland, Hubert (Ed.) Eine kleine deutsch-französische Literaturgeschichte vom 18. Jahrhundert bis zum Ersten Weltkrieg (in press)

Recherches sur la forme, la mise en page et le contenu des papyrus scolaires grecs et latins chrétiens d’Égypte

in Studi di Egittologia e di Papirologia (in press)

The spatial footprint of the non-ferrous metal industry in Lubumbashi

in Tropicultura (in press)

In the south-eastern part of the Katanga Province (Democratic Republic of the Congo), high concentrations of copper and cobalt are found in the soils of the well-known “Copper Belt”. Due to the dominant ... [more ▼]

In the south-eastern part of the Katanga Province (Democratic Republic of the Congo), high concentrations of copper and cobalt are found in the soils of the well-known “Copper Belt”. Due to the dominant south-eastern winds, the metallurgic industry in Lubumbashi has been the source of spatially concentrated atmospheric deposits of non-ferrous metal particles and associated substances in a cone-shaped zone, situated north-west of the metal processing site. The existence of this zone has been evidenced using two different techniques: firstly, by means of landscape metric comparisons of the vegetation and bare soil patterns in two study areas, one inside the pollution cone and one outside; secondly, by means of the theory on city perception developed by Kevin Lynch. Higher fragmentation and lower vegetation presence were observed inside the pollution cone, reflecting the negative impact of atmospheric deposits. Those differences were higher for sites closer to the emission source. Lynch’s approach outlined the negative impact of diverse industrial plants on the perception by the local population. Six pollution districts and several contaminated paths, limits, nodes and polluting landmarks were identified. Citizens even recognize them as part of the collective image of the city. [less ▲]

Zur Stellung des Deutschen in Belgien

in Rundbrief. Mitteilungsblatt des BGDV (in press), 29

Die Geheimnisse der Schrift: Heinrich von Kleists Poetik der Verschlossenheit und das Prinzip der Verschiebung in seinen Texten

in Brittnacher, Hans Richard; Von der Lühe, Irmela (Eds.) Risiko – Experiment – Selbstentwurf. Kleists radikale Poetik (in press)

Behavior of Deep Beams with Large Headed Bars

in ACI Structural Journal (in press)

While anchor heads are particularly useful in the case of large bars which require significant development lengths, the ACI code provides design guidance for bars #11 or smaller. This paper presents a ... [more ▼]

While anchor heads are particularly useful in the case of large bars which require significant development lengths, the ACI code provides design guidance for bars #11 or smaller. This paper presents a test of a large deep beam reinforced with a single #18 headed bar. The behavior of the beam is evaluated in comparison to the behavior of a specimen with more conventional reinforcement of 6#8 headed bars, and to the behavior of a specimen with lap-spliced anchor hooks. Despite the extreme detailing of the specimen with a single #18 bar, the beam had the same strength as the specimen with 6#8 bars. The compressive stress in front of the anchor head reached about 1.5 times the compressive strength of the concrete and the stress in the #18 bar reached about 414 MPa (60 ksi) before the beam failed in shear along a diagonal crack away from the anchorage zone. Shear strength calculations according to Appendix A of the ACI code showed that the current strut-and-tie provisions can overestimate the shear strength of deep beams by as much as 23%. [less ▲]

Levallois et Gravettien

in Praehistoria (in press)

Par opposition à ceux de l’Aurignacien, les ensembles lithiques gravettiens procèdent selon une méthode rappelant le Levallois quant à la préparation des supports. Mais les variations observables au sein ... [more ▼]

Par opposition à ceux de l’Aurignacien, les ensembles lithiques gravettiens procèdent selon une méthode rappelant le Levallois quant à la préparation des supports. Mais les variations observables au sein du Gravettien touchent autant les processus de symbolisation dans l’art et les sépultures. Elles affectent différents substrats eurasiatiques, plutôt septentrionaux, comme mis en réserve dès les Néandertaliens. [less ▲]