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  Efficient aseptic and automatable vitrification of human Embryonic Stem Cells using bio-safe & chemically defined mediaConnan, Delphine  ; Ectors, Fabien ; Grobet, Luc et alConference (2013, March 23) Detailed reference viewed: 26 (15 ULg)Le Blanc-bleu Belge, la génomique et moi...Sartelet, Arnaud Speech (2013) Detailed reference viewed: 9 (3 ULg)Particularités de la personne âgée maladePETERMANS, Jean Conference (2013, March 22) Detailed reference viewed: 19 (1 ULg)Des élites sans avenir. Contre-valeurs nobiliaires dans le roman dystopique francophoneStienon, Valérie Conference (2013, March 22) Le récit d’anticipation développe des représentations sociales complexes, en particulier lorsqu’il se centre sur les dissensions et dysfonctionnements d’une communauté en difficulté face au conflit ... [more ▼] Le récit d’anticipation développe des représentations sociales complexes, en particulier lorsqu’il se centre sur les dissensions et dysfonctionnements d’une communauté en difficulté face au conflit mondial, au cataclysme écologique ou au fléau biologique. Représentées sous cet angle, les sociétés futures semblent marquer la fin de la distinction sociale par les privilèges de la fortune, du territoire ou du titre, au profit d’une élite éclairée triomphant par le capital intellectuel, la maîtrise scientifique et la sophistication technologique. Pourtant, les scénarios littéraires de destruction imminente des biens matériels et de reconfiguration géopolitique planétaire montrent cette élite en fâcheuse posture et insistent volontiers sur son improductivité, ses conjectures farfelues, son autosuffisance et sa méconnaissance du lien social. Précipitant la fin d’une civilisation, dictateurs technocrates et savants-prophètes sont alors assimilés à une classe aristocratique à bannir, conviction qui motive notamment cette exclamation emportée : « Ces savants, ces aristocrates de la pensée, qu’on les pende ! » (Jacques Spitz, L’Agonie du globe, 1935). Conséquence de l’échec face à l’adversité, le franchissement régressif inverse du seuil nature/culture prépare une nouvelle hiérarchie anthropologique du sang. Elle se caractérise par une urgence de préservation vitale qui se substitue à l’impératif de pureté de la lignée à maintenir. L’imaginaire d’une décadence par le sang s’en trouve reconfiguré sous diverses formes : maladies sélectives selon le capital santé du degré d’ascendance (Daniel Halévy, Histoire de quatre ans, 1903) ; formes de vie parasites se nourrissant des globules rouges humains (Rosny Aîné, La Mort de la Terre, 1910) ; guerre bactériologique ciblée (Henri Allorge, Le Grand Cataclysme, 1922) ; anthropophagie due aux radiations des « machines à sang » alimentées par des corps humains (José Moselli, La Fin d’Illa, 1925), etc. Cette communication étudie la cohérence et l’évolution de ces constats thématiques dans une trentaine de romans parus entre 1900 et 1950, qui partagent les caractéristiques narratives de l’anticipation rationnelle négative. Trois aspects seront examinés en particulier : la constitution du point de vue narratif, la caractérisation des protagonistes et l’évolution diégétique déceptive. [less ▲] Detailed reference viewed: 14 (0 ULg)Perspectives thérapeutiques dans la migraineMAGIS, Delphine Scientific conference (2013, March 22) Detailed reference viewed: 11 (1 ULg)Scientific basis for transnational flood management in the Meuse basinDewals, Benjamin ; ; et alConference (2013, March 22) Detailed reference viewed: 32 (20 ULg)Effects of climate change on the river Meuse: Hydraulic 2D modeling from Amspin to Maaseik (and beyond); Dewals, Benjamin ; et alPoster (2013, March 22) Detailed reference viewed: 8 (4 ULg)Charlemagne en bord de Meuse. De l'histoire à la légendeClose, Florence Conference given outside the academic context (2013) Detailed reference viewed: 17 (0 ULg)L’Analyse du Cycle de vie : quoi, pourquoi, comment ?Léonard, Angélique Scientific conference (2013, March 22) Detailed reference viewed: 1 (0 ULg) Lower intracellular concentration of cryoprotectants in mouse zygotes after vitrification than after slow freezingConnan, Delphine ; ; Grobet, Luc et alPoster (2013, March 22) Detailed reference viewed: 13 (4 ULg)Pattern Recognition in NeuroImaging: What can machine learning classifiers bring to the analysis of functional brain imaging?Schrouff, Jessica Doctoral thesis (2013) The study of the brain development and functioning raises many question that are tracked using neuroimaging techniques such as positron emission tomography or (functional) magnetic resonance imaging ... [more ▼] The study of the brain development and functioning raises many question that are tracked using neuroimaging techniques such as positron emission tomography or (functional) magnetic resonance imaging. During the last decades, various techniques have been developed to analyse neuroimaging data. These techniques brought valuable insight on neuroscientific questions, but encounter limitations which make them unsuitable to tackle more complex problems. More recently, machine learning based models, coming from the field of pattern recognition, have been promisingly applied to neuroimaging data. In this work, the assets and limitations of machine learning based models were investigated and compared to previously developed techniques. To this end, two applications involving challenging datasets were defined and the results from widespread methods were compared to the results obtained using machine learning based modelling. More specifically, the first application addressed a research question: Is it possible to detect and characterize mnemonic traces? The fMRI experiment comprised a learning and a control tasks, both flanked by rest sessions. From previous studies, patterns of brain activity generated during the learning task should be spontaneously repeated during the following rest session, while no difference should be observed between the pre- and post-task rest session in the control condition. Using univariate and multivariate feature selection steps before a Gaussian Processes classification, mnemonic traces could be detected and their spatio-temporal evolution characterized. On the contrary, an analysis of the rest sessions based on the detection of independent networks did not provide any results supporting the theory of memory consolidation. The second application tackled a clinical issue: Can a pattern of brain activation characteristic to idiopathic Parkinson’s disease be detected and localized? The dataset considered to address this question comprised the fMRI images of aged healthy subjects and Parkinsonian patients while they were performing a task of mental imagery of gait at three different paces. The signal comprised in a priori selected regions of interest allowed for the support vector machines classification of healthy and diseased volunteers with an accuracy of 86%. To localize the discriminating pattern, a methodology based on the weight in labelled regions (e.g. from the anatomical automatic labelling or Brodmann atlases) was developed, which enabled the comparison between univariate and multivariate results and showed a nice overlap between them. Furthermore, models could then be compared quantitatively in terms of pattern localization, using a specifically defined measure of distance. This measure could then be used to compare the patterns generated from different folds of a same model, from different feature sets, or from different modelling techniques. The present study concluded that machine learning models can clearly and fruitfully complement other analysis techniques to tackle challenging questions in neuroscience. On the other hand, more work is needed in order to render the methodology fully accessible to the neuroscientific community. [less ▲] Detailed reference viewed: 92 (22 ULg)ACV et Ecoconception: illustration de la démarche au sein de Knauf Insulation.Gerbinet, Saïcha ; ; Léonard, Angélique Conference (2013, March 22) Detailed reference viewed: 14 (0 ULg)Melting of a Primitive Martian Mantle at 1 – 2 GPa: Experimental Constraints on the Origin of Basalts on MarsCollinet, Max ; ; Vander Auwera, Jacqueline et alPoster (2013, March 21) Detailed reference viewed: 20 (2 ULg)"'With love for my people': Chika Unigwe's Night Dancer"Tunca, Daria Conference (2013, March 21) Detailed reference viewed: 14 (1 ULg)Double stigmatisation dans la maladie d'Alzheimer: Impact pour les patients et leurs prochesAdam, Stéphane Conference given outside the academic context (2013) Detailed reference viewed: 69 (1 ULg)Les forêts vierges du Bassin du Congo - mythe ou réalité ?Morin-Rivat, Julie ; Bourland, Nils ; Gillet, Jean-François et alScientific conference (2013, March 21) Les forêts du bassin du Congo ont longtemps été considérées comme des massifs historiquement épargnés par l'action de l'homme. Des résultats plus ou moins récents de recherches scientifiques remettent en ... [more ▼] Les forêts du bassin du Congo ont longtemps été considérées comme des massifs historiquement épargnés par l'action de l'homme. Des résultats plus ou moins récents de recherches scientifiques remettent en question cette vision des forêt denses humides africaines. [less ▲] Detailed reference viewed: 127 (5 ULg)The Violence of Self-StarvationDelville, Michel ; Conference (2013, March 21) Detailed reference viewed: 6 (0 ULg)Retrospective analysis of Belgian experience with intestinal transplantation; DE ROOVER, Arnaud ; DETRY, Olivier et alConference (2013, March 21) Aim: The only alternative to Total Parenteral Nutrition (TPN) for complicated intestinal failure is Intesti- nal Transplantation (ITx) which is perceived as a high-risk procedure with inferior results ... [more ▼] Aim: The only alternative to Total Parenteral Nutrition (TPN) for complicated intestinal failure is Intesti- nal Transplantation (ITx) which is perceived as a high-risk procedure with inferior results compared to other organ Tx. Therefore ITx has been rarely applied in Belgium. In a multicenter retrospective review, we analyzed the overall Belgian experience with ITx. Methods: The Belgium Liver Intestine Committee organized a survey among all Belgian Tx centers, based on the patient-specific data form of the international ITx registry. Overall activity and indications were reviewed. Patient/graft survival was calculated (Kaplan-Meier). Nutritional (TPN) independence and Quality of Life (QoL) (Karnofsky score) were analyzed. Results: 21 ITx were performed in 20 patients (03/99-11/12), distributed among 5 centers: KUL (12), ULg (5), UZG (2), UCL (1), UZA (1). Median age was 38y(8mo-56y). Male/female ratio was 10/10. 5 were pediatrics (<18y) and 15 adults. Indications were anatomical or functional short bowel syndrome: intestinal ischemia(5), volvulus(5), Crohn(2), chronic intestinal pseudo-obstruction(2), splanchnic thrombosis(2), Churg-Strauss(1), necrotizing enterocolitis(1), microvillus inclusion(1), intestinal atresia(1) and chronic rejection of a first ITx(1). Most patients also suffered from TPN-associated com- plications (infection/shortage of venous access or liver failure). An isolated small bowel was trans- planted in 9 patients (plus kidney Tx in 2; plus pancreas Tx in 1); 10 received a combined liver and ITx; 2 received a multivisceral Tx. At time of Tx, 11 patients were hospitalized and 10 at home. 20 grafts were procured from deceased donors; one segmental intestinal graft was procured from a living donor. ABO blood group was identical in 63%, compatible in 37%. Median cold ischemia time was 5h30 ́(3h17 ́-9h31 ́). All patients received tacrolimus-based immunosuppression. Basiliximab (anti-IL2 receptor antibody) induction was administered in 16 patients. In 11 patients donor specific blood was transfused as part of an immunomodulatory protocol. 5-year patient and graft survival is 59% and 55.6%, respectively. 8 patients died: 6 to sepsis, 1 to intracerebral hemorrhage; 1 sudden death re- mained unexplained. 1 patient developed postTx lymphoma. 2 chronic rejections occured for which one reTx was performed. Of 12 survivors (median follow-up 1870 days), 11 are nutritionally independent (TPN-free) and 10 have a Karnofsky score >90%. Conclusions: ITx has come of age in Belgium. During the last 13 years, 21 ITx were performed in 5 centers. A 5-year patient/graft survival of 59%/55.6% is achieved, which is similar to results reported by the International ITx registry. In Belgium, awareness should grow that ITx represents a life-saving (and QoL improving) treatment in selected patients with reduced life expectancy due to significant complica- tions from TPN and intestinal failure. [less ▲] Detailed reference viewed: 6 (4 ULg)Utiliser l'esquisse numérique comme outil d'apprentissage de la conception - l'expérience du LUCID-ULgSafin, Stéphane Scientific conference (2013, March 21) Detailed reference viewed: 18 (0 ULg)Médias et communication politique : la presse, l'Open Vld et l'impôt sur la fortuneGeuens, Geoffrey E-print/Working paper (2013) Detailed reference viewed: 3 (2 ULg) |
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