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See detailThe Impact of Employee-Employer Relationships on Domestic Worker’s Achievement of Transnational Family-Work Balance
Vivas Romero, Maria ULg

Conference (2015, January 16)

While the average mainstream woman’s daily commute to work is 28 minutes, the ageing Peruvian domestic workers I have followed for the past year, crossed the Atlantic ocean 12 years ago for jobs in ... [more ▼]

While the average mainstream woman’s daily commute to work is 28 minutes, the ageing Peruvian domestic workers I have followed for the past year, crossed the Atlantic ocean 12 years ago for jobs in Europe’s capital. They found in Brussels the opportunity to be employed either in the informal or formal domestic sector while they continued to cope with their transnational obligations as spouses, daughters, and mothers. Transnational family and Global Care Chains literature have examined the consequences of migrant domestic workers’ double role as mothers and workers abroad. My contribution takes the discussion one step further and examines how, in spite of their disadvantaged position within the global division of labor, these women manage to informally negotiate a transnational family-work balance. My analysis, based on the life-stories of two ageing Peruvian women, suggests that domestic-workers’ success in their negotiations for transnational family-work balance simultaneously depends on three factors: 1- their gender, race, and class positioning within the migratory, care, and welfare regimes of sending and receiving states, 2- their ability to circulate familial care transnationally through the different stages in their life-course, 3- the business or personalized relationship that they established through their life-course with their employers. Furthermore, this analysis shows that employers are key actors in domestic workers’ negotiation, not only of a family-work balance, but also simply for social protection, especially in their old age. Finally, I suggest that the analysis of these complex employer-employee negotiations may allows us to see how these particular domestic workers are taking small steps to professionalize their work while paving the way to erase the historical vestiges associated with it. [less ▲]

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See detailRaymond M. Lemaire (1921-1997) et la conservation de la ville ancienne. Approche historique et critique de ses projets belges dans une perspective internationale
Houbart, Claudine ULg

Doctoral thesis (2015)

The specialised centre for conservation of the KU Leuven wears his name. Raymond M. Lemaire (1921-1997), art historian, is unanimously and internationally considered as one of the key figures of heritage ... [more ▼]

The specialised centre for conservation of the KU Leuven wears his name. Raymond M. Lemaire (1921-1997), art historian, is unanimously and internationally considered as one of the key figures of heritage conservation in the second half of the twentieth century. His name is immediately associated to the writing of the Venice charter, the foundation of ICOMOS or Unesco missions such as the restoration of the Acropolis or the Borobudur temples. But his work in Belgium, in the field of urban renovation is to a great extend ignored, with the exception of the Great beguinage of Leuven. Starting from Lemaire's personal archives, handed over to the KU Leuven after be became professor emeritus in 1991, our study aims at revealing his vision of urban rehabilitation, on the basis of microhistorical case-studies mostly situated in Brussels and of his contributions to the elaboration of an appropriate doctrine for the renovation of city centres. Considering this vision in relation with his practice in the field of urbanism, well illustrated by the planning of Louvain-la-Neuve, has lead us to see in Raymond M. Lemaire an updating of the "integral architect", an essential concept formulated by Gustavo Giovannoni at the beginning of the twentieth century. [less ▲]

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See detailPurinergic control of inflammation and thrombosis: Role of P2X1 receptors
Oury, Cécile ULg; LECUT, Christelle ULg; Hego, Alexandre ULg et al

in Computational and Structural Biotechnology Journal (2015), 13

Inflammation shifts the hemostatic mechanisms in favor of thrombosis. Upon tissue damage or infection, a sudden increase of extracellular ATP occurs, that might contribute to the crosstalk between ... [more ▼]

Inflammation shifts the hemostatic mechanisms in favor of thrombosis. Upon tissue damage or infection, a sudden increase of extracellular ATP occurs, that might contribute to the crosstalk between inflammation and thrombosis. On platelets, P2X1 receptors act to amplify platelet activation and aggregation induced by other platelet agonists. These receptors critically contribute to thrombus stability in small arteries. Besides platelets, studies by our group indicate that these receptors are expressed by neutrophils. They promote neutrophil chemotaxis, both in vitro and in vivo. In a laser-induced injury mouse model of thrombosis, it appears that neutrophils are required to initiate thrombus formation and coagulation activation on inflamed arteriolar endothelia. In thismodel, by using P2X1−/−mice,we recently showed that P2X1 receptors, expressed on platelets and neutrophils, play a key role in thrombus growth and fibrin generation. Intriguingly, in a model of endotoxemia, P2X1−/−mice exhibited aggravated oxidative tissue damage, along with exacerbated thrombocytopenia and increased activation of coagulation, which translated into higher susceptibility to septic shock. Thus, besides its ability to recruit neutrophils and platelets on inflamed endothelia, the P2X1 receptor also contributes to limit the activation of circulating neutrophils under systemic inflammatory conditions. Taken together, these data suggest that P2X1 receptors are involved in the interplay between platelets, neutrophils and thrombosis. We propose that activation of these receptors by ATP on neutrophils and platelets represents a new mechanism that regulates thrombo-inflammation. [less ▲]

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See detailLa mise en abyme vidéoludique comme vecteur d’une immersion au second degré : une analyse du jeu The Stanley Parable
Barnabé, Fanny ULg; Dozo, Björn-Olav ULg

Conference (2015, January 16)

Par sa nature même, le jeu entretient avec la réflexivité une parenté certaine. En effet, pour qu’une situation ou un objet soit reconnu comme ludique par les participants, il est nécessaire que ces ... [more ▼]

Par sa nature même, le jeu entretient avec la réflexivité une parenté certaine. En effet, pour qu’une situation ou un objet soit reconnu comme ludique par les participants, il est nécessaire que ces derniers superposent à leur action le message « ceci est un jeu » (Bateson, 1977). L’acte ludique, le « jouer » (Henriot, 1989), constitue donc un procédé de « méta-communication » (Bateson, 1977) supposant une interaction au second degré avec le réel (le joueur « fait comme si » ; Schaeffer, 1999). Le jeu vidéo n’échappe pas à cette dynamique réflexive, comme en témoigne le nombre important d’œuvres vidéoludiques qui – par le biais de différents outils formels – discourent sur leur propre organisation ludo-narrative, sur leurs possibilités d’utilisation ou sur le médium qui les supporte. Envisageant la mise en abyme comme l’un des procédés réflexifs – parmi d’autres – dont peut user le jeu vidéo, la présente communication visera à étudier les particularités de cette forme de représentation liées à son inclusion dans un environnement ludique. La mise en abyme vidéoludique rompt-elle l’immersion du joueur, le « cercle magique » (Huizinga, 1950) ? Permet-elle l’élaboration d’un univers fictionnel cohérent malgré le fait qu’elle rappelle le joueur à son statut d’utilisateur ? A-t-elle nécessairement une vocation critique ou peut-elle constituer une fin en soi, un dispositif ludique à part entière ? Pour répondre à ces interrogations, nous nous intéresserons à un cas exemplaire de mise en abyme vidéoludique : le jeu The Stanley Parable. Celui-ci met en perspective l’action du joueur en lui faisant incarner le personnage de Stanley, dont le travail consiste à appuyer sur des boutons en suivant un ordre et une fréquence qui lui sont dictés par un ordinateur. Ce jeu d’aventure pousse la logique réflexive à un point tel (elle constitue son fondement ludique, narratif et esthétique) qu’il met en question sa force évocatrice et sa validité : l’accumulation des mises en abyme (reflétant l’expérience du joueur mais aussi l’histoire du jeu vidéo en général) empêche effectivement toute prise au sérieux du récit, tout investissement au premier degré. En multipliant les méta-énoncés, The Stanley Parable fait de la mise en abyme un système de règles en soi (un game) dont le principe ludique repose sur la manipulation des codes mêmes du jeu vidéo : le game designer y engage le joueur dans une lutte (un play) dont l’enjeu n’est autre que la maîtrise du langage vidéoludique. [less ▲]

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See detailLow molecular weight poly (2-dimethylamino ethylmethacrylate) polymers with controlled positioned fluorescent labeling: Synthesis, characterization and in vitro interaction with human endothelial cells.
Flebus, Luca ULg; Lombart, François ULg; Sevrin, Chantal et al

in International journal of pharmaceutics (2015), 478(1), 278-287

Poly (2-dimethylamino ethylmethacrylate) (PDMAEMA) is an attractive non-degradable polymer studied as nonviral vector for gene delivery but it can be also adopted for delivery of other biopharmaceutical ... [more ▼]

Poly (2-dimethylamino ethylmethacrylate) (PDMAEMA) is an attractive non-degradable polymer studied as nonviral vector for gene delivery but it can be also adopted for delivery of other biopharmaceutical drugs. As a parenteral carrier, the PDMAEMA free form (FF) might interact with tissues and cells. Few data are available on its selective internalization and efflux from cells, while the majority of studies published have followed the distribution of DNA complexed with PDMAEMA. In order to address polycation safety, the first aim was to synthesize by atom transfer radical polymerisation (ATRP) fluorescent labeled PDMAEMA of low molecular weight (Mw) (below 15kDa), controlling the position and density of fluorescein. The second goal was to analyze the possible difference in uptake and subcellular distribution of this labeled FF polycation between human umbilical vein endothelial cells (HUVEC) and hCMEC/D3 cells. These two cell lines have been chosen in order to detect selectivity towards the blood-brain barrier (BBB). In both cases, polycation was detected along the plasma membrane followed by progressive migration to the peri-nuclear region, where it overlapped with lysosomal structures. The analysis by fluorescence-activated cell sorting (FACS) of the PDMAEMA uptake by hCMEC/D3 cells showed a significant (p<0.05) inhibition (40%) in presence of 2-dexoxy-d-glucose inhibitor, a result supporting an energy-dependence mechanism(s). Cytotoxicity study showed that low Mw PDMAEMA (10kDa) lead to a minor cytotoxicity compared to the higher ones. As main conclusion this study highlights the similitude in cell trafficking of FF PDMAEMA and data previously reported for PDMAEMA/DNA complexes. [less ▲]

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See detailMiracle ou péril jaune? La pénétration chinoise en Amérique latine
Wintgens, Sophie ULg

Article for general public (2015)

Qu’elle fascine ou qu’elle rebute, qu’elle soit synonyme d’opportunités ou porteuse de défis, la Chine est aujourd’hui devenue un acteur incontournable des relations internationales. Deuxième économie ... [more ▼]

Qu’elle fascine ou qu’elle rebute, qu’elle soit synonyme d’opportunités ou porteuse de défis, la Chine est aujourd’hui devenue un acteur incontournable des relations internationales. Deuxième économie mondiale en passe de dépasser les États-Unis, la montée en puissance de cet État-continent qui représente à lui seul un cinquième de la population de la planète met dès lors la notion de pouvoir mondial en question. La Chine est-elle une puissance mondiale à même de concurrencer, voire détrôner, la domination américaine ? Qu’en est-il en particulier de sa pénétration récente en Amérique latine, une région du monde que les États-Unis considèrent historiquement comme leur arrière-cour et l’Union européenne (UE) comme une importante zone d’influence ? [less ▲]

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See detailEuthanasie et internement : une logique perverse ?
Englebert, Jérôme ULg

Article for general public (2015)

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See detailINTERNATIONAL WORKSHOP Employment relationships in migrant domestic work: a transnational perspective
Safuta, Anna; Camargo, Beatriz; Vivas Romero, Maria ULg

Scientific conference (2015, January 15)

Domestic work provided by migrants in private households, both formally and informally, has been on the agenda of researchers and policymakers since the early 2000s. Employment relationships between ... [more ▼]

Domestic work provided by migrants in private households, both formally and informally, has been on the agenda of researchers and policymakers since the early 2000s. Employment relationships between migrant workers and employers in this sector remain however underexplored, in particular in European contexts. Three aspects deserve further examination: the comparison between formal and informal settings, differences between childcare, elderly care and housework provision, as well as the links between inter-individual relations and policies. The main objective of this International Workshop is to open new perspectives in the study of employment relationships in domestic work, and to promote transnational and cross-disciplinary exchange between scholars studying the topic. This International Workshop featured keynote lectures by confirmed academics with expertise in migrant domestic work, followed by workshops open to early career researchers (PhD student-level and up). Theses workshops allowed selected participants to discuss papers submitted in advance with senior academics investigating domestic work, care and migration. The Workshop aimed to make the most of new methodological perspectives in the sociology of migration, promoting a transnational approach in the study of domestic work. The objective was also to bring employment relationships in migrant domestic work out of the shadow of the private sphere and allow discussion between academics specializing in this area of investigation. We welcomed researchers investigating both micro and macro aspects of migrant domestic work. Questions of interest included the personalization of the employment relationship between migrant domestic workers and private employers; differences between employment relations in housework, elderly care and childcare; as well as the influence on employment relationships of ‘otherness’ in the private space, of the formalization of employment and/or regularization of migratory status, and of different migratory and care regimes. Transnational perspectives are particularly welcome. This International Workshop was organized in the framework of the Social Sciences Thematic Doctoral School of the Wallonia-Brussels Federation – Program “Migrations and Interculturality” (École doctorale thématique en sciences sociales de la Fédération Wallonie-Bruxelles – Programme «Migrations et Interculturalité»), coordinated by Université libre de Bruxelles (ULB), Université catholique de Louvain (UCL) and Université de Liège (ULg). [less ▲]

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See detailTransport et environnement
Ozer, Pierre ULg

Scientific conference (2015, January 15)

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See detailQuid des acquis culturels de nos élèves au sortir du secondaire ? Étude transversale (2002-2009)
Jadoulle, Jean-Louis ULg; Stevens, Xavier ULg

Scientific conference (2015, January 14)

La recherche dont il est fait état porte sur la culture historique scolaire. Quels sont les "savoirs culturels" à caractère historique des élèves de 6e année de l'enseignement secondaire général ? Quel ... [more ▼]

La recherche dont il est fait état porte sur la culture historique scolaire. Quels sont les "savoirs culturels" à caractère historique des élèves de 6e année de l'enseignement secondaire général ? Quel est leur niveau de maîtrise de ces savoirs ? Dans quelle mesure cette maîtrise dépend-t-elle de l'indice socio-économique moyen de l'école et de la filière d'enseignement qu'ils fréquentent ? Ou du profil de l'école ? Comment cette maîtrise a-t-elle évolué durant la période 2002-2009, soit celle au cours de laquelle les nouveaux programmes, inspirés de l'approche par compétences, ont été implémantés ? [less ▲]

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See detailIntroduction to item response theory (IRT) and computerized adaptive testing (CAT) with the R software
Magis, David ULg

Scientific conference (2015, January 13)

Item response theory (IRT) has become an important field of research for psychology and educational assessment. Recently, with the increase of computational power, several IRT-related topics have emerged ... [more ▼]

Item response theory (IRT) has become an important field of research for psychology and educational assessment. Recently, with the increase of computational power, several IRT-related topics have emerged, among others, computerized adaptive testing (CAT). The main aim of CAT is to provide a framework for individualized assessment by means of optimal item selection and administration to the test takers. CAT has several assets to linear (non-adaptive) testing: individualized assessment, limited risk of cheating or fraud, shorter tests providing the same amount of information as longer linear tests, automatic scoring and reporting at the end of the test. Practical use of CAT, however, remains limited so far due to several factors (lack of available large item banks, content validity and security, lack of suitable software for practical CAT assessment, ethical issues in administering different tests to estimate the same ability, etc.). The purpose of this workshop is threefold: (a) to provide a general overview of IRT and CAT, (b) to introduce the R software in a user-oriented way, as well as several IRT tools (including the package catR for CAT simulations), (c) to perform practical training sessions with the participants. The workshop will be a mix of oral presentations, demonstrations related to the R software, and practical sessions where participants will be invited to train with R and catR. The R software is an open-source platform for statistical inference and testing, graphical display and data visualization. It also holds several add-on packages for specific IRT purposes (item calibration, ability estimation, multidimensional scaling, equating, differential item functioning etc.). The R community is worldwide and proposes free exchanges of shared R packages through the CRAN (comprehensive R archive network). In this workshop, the R package catR will be examined and used in the practical sessions. [less ▲]

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See detailLes institutions politiques belges après la sixième Réforme de l'État
Grandjean, Geoffrey ULg

Learning material (2015)

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See detailGrandeur et misère du système politique belge
Grandjean, Geoffrey ULg

Conference given outside the academic context (2015)

Detailed reference viewed: 11 (0 ULg)
See detailFeedback loops: From cellular to network principles
Dethier, Julie ULg

Scientific conference (2015, January 12)

Biological rhythms play a major role in the functioning of the brain. However, the generation mechanisms and functions of these rhythms are still under debate and the question of which cellular details ... [more ▼]

Biological rhythms play a major role in the functioning of the brain. However, the generation mechanisms and functions of these rhythms are still under debate and the question of which cellular details must be retained at the network level is largely open. In this presentation, I will highlight that cellular properties have a major impact at the network level, especially in the study of modulation and robustness. I will focus on a particular cellular property, a positive feedback loop in a specific timescale, and illustrate its network level impact with two simple examples: the modulation and robustness of an half-center oscillator, a very simple central pattern generator composed of two reciprocal-inhibitory populations, and the control of transient beta-band oscillations in the basal ganglia, a group of subcortical nuclei that act as a cohesive functional unit, in relation to motor movements. [less ▲]

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See detailProfession art-thérapeute?
Vandeninden, Elise ULg

Conference (2015, January 09)

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See detailManaging the carnivore comeback: assessing the adaptive capacity of the Eurasian lynx (Lynx lynx) to cohabit with humans in shared landscapes
Bouyer, Yaëlle ULg

Doctoral thesis (2015)

Conflicts between humans and large carnivores are one of the most visible examples of the challenges that arise when seeking to achieve coexistence between humans and wildlife. With their large spatial ... [more ▼]

Conflicts between humans and large carnivores are one of the most visible examples of the challenges that arise when seeking to achieve coexistence between humans and wildlife. With their large spatial requirements and predatory behavior, large carnivores are among the most difficult species to preserve in our modern day landscapes. Although large carnivores are usually considered as the epitomes of wilderness, because of human population growth and habitat fragmentation they are inexorably and increasingly faced with the need to live in human-modified landscapes. As a direct consequence, conflicts over depredation on livestock, competition for game species and sometimes over human injury or death will only increase if clear management measures are not taken. This is particularly true in Europe, where, after many decades of absence, large carnivores are recolonizing areas where millions of people are present and where landscapes have been drastically modified. Two approaches to integrating wildlife into a human-dominated world have been proposed at an international scale. The first solution is called land sparing, in which wildlife lives exclusively in protected or wilderness areas where contact between animals and humans will be reduced to the minimum. The second solution, called land sharing, proposes to integrate human activities and wildlife in the same landscapes in non-protected interface zones in what is often called a coexistence approach. In a context of scarce true wilderness areas and a continuum of human-modified habitats, land sharing (i.e. the coexistence approach) is seen as the only possible approach valid for Europe. While a coexistence approach can be readily implemented with smaller species, it can represent a major challenge for species with large space requirements and with predatory behavior. To help manage these species in a long-term conservation vision and to predict where potential conflicts could arise between humans and carnivores, information on large carnivores and their habitat use in anthropogenic landscapes is a pre-requisite. With the return of Eurasian lynx Lynx lynx in Western Europe, the most densely populated areas of the continent_ information on the species tolerance to human land use will help predict where it is likely to occur in anthropogenic landscapes. Data collected in Scandinavia over 15 years were used to assess the use of landscape by lynx. In this study, we explored the effect of anthropogenic and environmental factors on Eurasian lynx habitat use in Scandinavia. The work was developed along two main axes. The first axis aims to explore large scale potential patterns of lynx distribution through transferability of results obtained from habitat modelling to geographically different areas. Transferability of results was tested in two steps. Firstly, transferability success (i.e. predictive ability of the map) was tested at a regional scale using data on roe-deer, the main prey of lynx, to create a map of relative distribution and abundance of prey in southeastern Norway (Chapter 1). Secondly, transferability success was assessed at a larger extent and using data obtained from different sampling method (Chapter 2). A habitat suitability map for Eurasian lynx was produced to be used in management planning in geographically differentiated lynx management zones in Scandinavia. The results indicated that transferability of results from one region to an ecologically different region must be taken with caution. Nevertheless, the habitat suitability maps we constructed on the basis of extrapolation are a valuable asset to help management of the Scandinavian lynx population. The second axis deals with lynx habitat use in relation to anthropogenic and environmental predictors. Lynx tolerance to human presence was first explored by looking at the orientation of home range in the landscape, taking into account proxies of human presence (Chapter 3). Values of these proxies were compared both inside home ranges and within a buffer surrounding the home ranges for several lynx inhabiting an anthropogenic gradient going from near-wilderness to urban periphery. Results showed a high diversity in the extent to which individual lynx are exposed to human influence, indicating that lynx are highly adaptable in terms of living space. Lynx seemed to be able to orientate their home range in order to avoid highest human impacts and select for areas of medium human impacts. Building on these results, finer scale information on lynx habitat use in an anthropogenic landscape were obtained taking into consideration different types of behavior (day-beds, moving and killing) displayed by adult lynx, as well as the effect of cumulative anthropogenic pressures on habitat selection (Chapter 4). Our results showed that lynx select for areas with medium levels of human modification, avoiding both the areas with highest and least modification. Females in general appear to be less tolerant to human modification than males, especially for day-beds. Our study shows that Eurasian lynx can be considered as a species that is adaptable to human- induced changes in landscape even if its motivation to tolerate human presence is clearly linked to the presence and density level of its main prey, the roe deer. Our work shows that, contrary to much of the public and many conservation professionals’ opinions, land sharing with large carnivores in Europe may be possible – even in the immediate proximity to urban centers. However, it is important to bear in mind that these results were obtained from countries with a relatively low human population density; even though some individuals observed lived in the periphery of large cities, the level of habitat fragmentation is less severe than in most of Western Europe. In order to properly assess the capacity of Eurasian lynx to live in highly populated areas, such as the Benelux, more detailed information on lynx distribution from continental European will be needed. However, our results underline the value of combining both correlational and mechanistic studies, and the need for caution in extrapolating data too far from its original context. As large carnivore recovery continues to progress in Europe we may not yet have seen the limits of these species' abilities to adapt. [less ▲]

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See detailImproving the performance of μ-ORC systems
Declaye, Sébastien ULg

Doctoral thesis (2015)

This thesis contributes to the knowledge and the characterization of micro Organic Rankine Cycles (ORC). It is based on experimental data and simulation models. An oil-free scroll expander is tested in a ... [more ▼]

This thesis contributes to the knowledge and the characterization of micro Organic Rankine Cycles (ORC). It is based on experimental data and simulation models. An oil-free scroll expander is tested in a wide range of operating conditions in order to better characterize its performance. Particular attention is paid to the tightness of the machine which is obtained using a magnetic coupling. The measured isentropic efficiency reaches 75% which is higher than typical values reported in the literature. From the experimental results, a performance map of the expander is generated. This performance map can be used to provide fast and accurate calculation of the volumetric and isentropic performance of the expander in a wide range of operating conditions. Five displacement pumps adapted to μ-ORC systems are also tested. These pumps are diaphragm, piston, plunger and gear types. The measured values include the overall efficiency, the volumetric efficiency and the NPSH. A deep analysis of the performance is performed to quantify the losses of each pump, of their electric motor and of their frequency drive. This analysis shows that the weakness of the overall effectiveness (max. 46%) of the pumps tested is mainly due to the low efficiency of the electric motor. A semi-empirical model of the diaphragm pump is proposed and validated based on manufacturer data. This model can predict the mechanical power of the pump and the flow delivered with a good accuracy. The simulation models developed for the expander and the pump are used to simulate a configuration including the pump, the generator and the expander on a single shaft. This configuration aims to avoid the use of a motor and a frequency drive whose performance is poor in the range of power consumed by the pump of a μ-ORC system. The results show a significant increase in the net power produced using the integrated configuration Finally, performance of a prototype of μ-ORC suitable for recovering heat from a two-stage screw compressor are measured and analyzed. The prototype allows generating maximum 3.9% of the electrical power consumed by the compressor. Several optimization options of the prototype are evaluated numerically, showing that the power generation could be increased up to 5.4% of the compressor consumption. These options include using the integrated configuration and optimizing the intercooler boiler design. [less ▲]

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