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See detailProtein encapsulation and release from PEO-b-polyphosphoester templated calcium carbonate particles
Ergül, Zeynep ULg; Cordonnier, Thomas; Debuigne, Antoine ULg et al

in International Journal of Pharmaceutics (2016), 513

Calcium carbonate particles are promising candidates as proteins carriers for their controlled delivery in the body. The present paper aims at investigating the protein encapsulation by in situ ... [more ▼]

Calcium carbonate particles are promising candidates as proteins carriers for their controlled delivery in the body. The present paper aims at investigating the protein encapsulation by in situ precipitation of calcium carbonate particles prepared by a process based on supercritical CO2 and using a new type of degradable well-defined double hydrophilic block copolymers composed of poly(ethylene oxide) and polyphosphoester blocks acting as templating agent for the calcium carbonate. For this study, lysozyme was chosen as a model for therapeutic protein for its availability and ease of detection. It was found that by this green process, loading into the CaCO3 microparticles with a diameter about 2 mm can be obtained as determined by scanning electron microscopy. A protein loading up to 6.5% active lysozyme was measured by a specific bioassay (Micrococcus lysodeikticus). By encapsulating fluorescent-labelled lysozyme (lysozyme-FITC), the confocal microscopy images confirmed its encapsulation and suggested a core–shell distribution of lysozyme into CaCO3, leading to a release profile reaching a steady state at 59% of release after 90 min. [less ▲]

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See detailLes indices de détection de patron de réponse inapproprié de type carré-moyens non-pondérés: à manipuler avec précaution!
Beland, Sebastien; Raiche, Gilles; Magis, David ULg et al

Conference (2016, November 17)

Le carré-moyen non-pondéré U comme indice de détection (unweighted mean square statistics) (Wright & Stone, 1979) et sa version standardisée ZU (Wright, 1980) sont parmi les indices de détection de ... [more ▼]

Le carré-moyen non-pondéré U comme indice de détection (unweighted mean square statistics) (Wright & Stone, 1979) et sa version standardisée ZU (Wright, 1980) sont parmi les indices de détection de patrons de réponse inappropriés paramétriques les plus connus. On retrouve l’un et/ou l’autre de ces indices dans des logiciels commerciaux ou gratuits tels que RUMM2030, FACETS ou la librairie R eRm en plus d’en faire mention dans les articles les plus cités sur le sujet (Karabatsos, 2003; Meijer et Sijtsma, 2001). Durant les dernières décennies, quelques voix se sont élevées afin de sensibiliser les utilisateurs aux problèmes que présentent U et ZU (Karabatsos, 2000; Smith, 1991). Ils semblent, en effet, présenter des scores extrêmes qui rendraient leur utilisation inadéquate dans certaines situations. Cette présentation aura comme objectif d’étudier les limites des indices U et ZU. Nous utiliserons une étude de simulation et différents modèles de réponses à l’item dichotomiques afin de soutenir notre propos. Les auteurs de l’étude concluront leur présentation en discutant de l’importance de manipuler ces indices avec précaution. [less ▲]

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See detailLes juristes internationalistes belges et la crise européenne de 1866
Genin, Vincent ULg

Conference (2016, November 17)

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See detailRapport sur l'Habilitation de Catherine GUYON : Par la roue de sainte Catherine. Dévots, pèlerins et pèlerinage à sainte Catherine d’Alexandrie (VIIIe- début du XVIe siècle)
George, Philippe ULg

Report (2016)

Madame Guyon a étudié le culte de sainte Catherine d'Alexandrie et son développement tous azimuts.

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See detailShear banding simulation in clay rock around an underground opening, and its contact mechanism with the gallery’s lining
Charlier, Robert ULg; Salehnia, Fatemeh

in Proc. 5th International conference on geotechnical engineering and soil mechanics (2016, November 15)

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See detailCarbon balance of an intensively grazed grassland in southern Belgium
Gourlez de la Motte, Louis ULg; Jérôme, Elisabeth; Mamadou, Ossénatou et al

in Agricultural and Forest Meteorology (2016), 228-229

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See detailImages et figures. Dispositifs de re-découpage du sensible (Rancière)
Hagelstein, Maud ULg

Conference (2016, November 12)

Dans son historiographie critique (Les noms de l’histoire, 1992 / Figures de l’histoire, 2012), J. Rancière définit pour l’époque contemporaine des formes alternatives de poétique, de mise en récit et de ... [more ▼]

Dans son historiographie critique (Les noms de l’histoire, 1992 / Figures de l’histoire, 2012), J. Rancière définit pour l’époque contemporaine des formes alternatives de poétique, de mise en récit et de mise en visibilité de l’histoire, qui auraient pour effet de mieux prendre en compte les anonymes et de découper autrement le sensible. Dans de nombreux textes (cf. par ex. Le destin des images, sur la « phrase-image »), Rancière étudie les formes d’accompagnement entre images et mots, et pense la figurabilité comme articulation de deux pouvoirs expressifs en un agencement spécifique. Pour échapper au débat stérile sur la préséance de l’image sur le langage (ou vice-versa), on envisagera avec Rancière l’idée selon laquelle l’image serait une « manière dont les choses parlent et se taisent ». L’image ne dit pas mieux les intensités que les mots, mais elle aménage un lieu inédit pour la mise en fiction des paroles de l’histoire. En ce sens spécifique, la figurabilité, comme mise en scène des mots et des images, doit pouvoir compter sur le travail de l’indétermination – comme on le montrera avec quelques exemples cinématographiques. [less ▲]

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See detailElektrodynamische Fragmentierung von Elektroschrott
Iseli, Cédric; Streicher-Porte, Martin; Martino, Rémi ULg et al

Poster (2016, November 11)

Untersuchungen dazu werden in diesem Bericht am Beispiel von WEEE und speziell an Leiter-platten aufgezeigt. Die Versuche zeigen, dass EDF für verschiedenste Arten von Elektroschrott eingesetzt werden ... [more ▼]

Untersuchungen dazu werden in diesem Bericht am Beispiel von WEEE und speziell an Leiter-platten aufgezeigt. Die Versuche zeigen, dass EDF für verschiedenste Arten von Elektroschrott eingesetzt werden kann. Verschweisste Kompaktgeräte können zum Beispiel so weit geöffnet werden, dass die ge-wünschte Komponente freigelegt und entfernt werden kann. Leiterplatten haben die Eigenschaft, dass bei kontinuierlich steigendem Energieeintrag zuerst die aufgebrachten Komponenten abgetrennt werden, bevor die Cu-Bahnen freigelegt werden. Bei noch höherem Energieeintrag wird die Leiterplatte schlussendlich zerkleinert und vollständig zer-stört. Durch diese Entfrachtung der Leiterplatte kann ein metallreiches Konzentrat hergestellt werden. [less ▲]

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See detailReprint of Advancing the integration of corporate sustainability measurement, management and reporting
Maas, Karen; Schaltegger, Stefan; Crutzen, Nathalie ULg

in Journal of Cleaner Production (2016), 136

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See detailIntegrating corporate sustainability assessment, management accounting, control, and reporting
Maas, Karen; Schaltegger, Stefan; Crutzen, Nathalie ULg

in Journal of Cleaner Production (2016), 136

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See detailLes traités de paix et la Société des Nations
Genin, Vincent ULg

Conference given outside the academic context (2016)

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See detailSpeech style manipulations in dysarthria in French-speaking children: Acoustic findings.
Ancelle, Josephine; Moya Gale, G.; Hetrick, B et al

Poster (2016, November)

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See detailMeasurements of reference ISO nozzles by high-speed imaging
De Cock, Nicolas ULg; Massinon, Mathieu ULg; Nuyttens, David et al

in Crop Protection (2016), 89

Agricultural spray characteristics determine the efficiency of a pesticide application because size and velocity affect droplet trajectory and impact behavior. At present, the relevance of different ... [more ▼]

Agricultural spray characteristics determine the efficiency of a pesticide application because size and velocity affect droplet trajectory and impact behavior. At present, the relevance of different characterization techniques remains controversial since discrepancies may be significant between measurements performed in different laboratories. A digital image acquisition technique and analysis algorithm is proposed for droplet size and velocimetry measurements as an alternative to well-established techniques such as the Phase Doppler Particle Analyzer (PDPA) or laser diffraction spectrometry (LDS). The algorithm requires double exposed shadow images acquired in a back-lighted arrangement with a Particle Image Velocimetry (PIV) camera and a pulsed light emitting diode (LED). Spatial illumination heterogeneities are corrected by subtracting from each image a mean background acquired on several images without any particle. The algorithm accuracy is ensured by the rejection of out-of-focus particles using a focus parameter depending on gradient intensity at the particle edges. Thresholds for focus particle selection were determined by studying the evolution of the focus parameter and the error on particle size measurements from images containing droplets with uniform size at various distance of the object plane. Selected droplets were identified on both pairs of images to determine their size and velocity. Droplet size distributions were corrected to account for the uneven sampling probability caused by the volumetric method. Droplet size distributions of a set of reference nozzle/pressure combinations defined in the ISO/DIS 25358 were measured. The image technique was able to distinguish each of the reference sprays well. Comparison with PDPA measurements showed that the imaging technique tends to measure an equivalent Dv50, a lower Dv10 and a higher Dv90 leading therefore to a higher relative span factor. Velocity measurements showed good agreement between both techniques except for one nozzle/pressure combination. [less ▲]

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See detailReverse Traceroute with DisNETPerf, a Distributed Internet Paths Performance Analyzer
Wassermann, Sarah ULg; Casas, Pedro

in Proc. Demonstrations of the 41th Annual IEEE Conference on Local Computer Networks (LCN-Demos 2016) (2016)

Traceroute is the most widely used Internet path diagnosis tool today. A major limitation of traceroute when the destination is not controllable by the user is its inability to measure reverse paths, i.e ... [more ▼]

Traceroute is the most widely used Internet path diagnosis tool today. A major limitation of traceroute when the destination is not controllable by the user is its inability to measure reverse paths, i.e., the path from a destination back to the source. In this demo session, we showcase DisNETPerf, a new tool to perform reverse traceroute measurements. DisNETPerf is able to collect measurements from the server to the user for path performance monitoring and troubleshooting purposes, even when the server is not under the control of the experimenter. DisNETPerf uses RIPE Atlas, a largely distributed active measurements platform to perform traceroute measurements from any arbitrarily selected server in the Internet. [less ▲]

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See detailThe Base of Fabia Fabiana from Acci (Guadix, Granada). A Reassessment
Veymiers, Richard ULg; Gasparini, Valentino

Conference (2016, November)

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See detailEvaluation et gestion des scenarii de dysfonctionnement des barrages-réservoirs en Belgique
Liégeois, Benoît; Pirotton, Michel ULg; Dewals, Benjamin ULg et al

in Sûreté des barrages et enjeux (2016, November)

Belgium has fifteen structures included in the list of large dams of the International Committee on Large Dams. Six are managed by Engie Company, the other nine are owned by the Walloon regional public ... [more ▼]

Belgium has fifteen structures included in the list of large dams of the International Committee on Large Dams. Six are managed by Engie Company, the other nine are owned by the Walloon regional public authority. The Belgian legislator has never enacted specific rules for large dams. However, managers have always been concerned with this issue. They developed procedures and methods that were subject to exchanges of experience with their counterparts, in particular through the Belgian Committee on Large Dams. In this ongoing research of security, the impact of multiple failure scenarios (dam break, quick emptying …) on the people and the environment downstream of dams is a particular focal point. An impact study has been conducted for the main plants. This study is based on a deterministic numerical method. The methodology, the assumptions regarding the failure mode or emptying and the lessons learned from the analyses are presented. These results are an important step in the assessment and the management of risks. Indeed, regulations were recently enacted for the management and the coordination of any activity likely to seriously impact public safety during crisis periods. These rules apply therefore for large dams. In this context, managers have established an emergency plan for each structure. This paper provides a broad overview on the issues of the evaluation and the management of dysfunction risks of Belgian dams, as well as on approaches and collaborations initiated between the private managers and public authority. [less ▲]

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See detailLoadbearing capacity criteria in fire resistance testing
Dumont, Fabien ULg; Wellens, Eric ULg; Gernay, Thomas ULg et al

in Materials and Structures (2016), 49(11), 4565-4581

The European system for fire testing and classification of loadbearing building elements lacks consistency because the two standards that have to be applied prescribe different criteria for assessing the ... [more ▼]

The European system for fire testing and classification of loadbearing building elements lacks consistency because the two standards that have to be applied prescribe different criteria for assessing the loadbearing performance. This article analyzes the implications of the present conflict between the standard for testing and the standard for classification. The prescribed criteria for loadbearing performance are related to the exceedance of deflection and rate of deflection thresholds. A database of 46 fire resistance tests performed at the University of Liege is collected that contains the time at which these thresholds are reached in fire tests with different typologies of elements (walls, floors, columns and beams). Then, the loadbearing performance (and hence the fire resistance rating) can be derived according to the two standards. The evolutions of deflection and rate of deflection during the tests are also analyzed to gain a better understanding of the adequacy of the standards. The selection of one or the other standard affects the time at which “failure” is deemed to occur in fire tests. Statistically speaking, the difference in terms of failure time that results from using one or the other standard has a 25% probability to exceed 10%. In certain cases, this results in a difference in fire resistance rating; this was observed for 3 of the analyzed tests. The apparent contradiction in two codes in application has potential practical implications and therefore needs to be solved. The article suggests some guidelines for defining homogenized and consistent criteria. [less ▲]

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See detailStability and Consistency of the LISP Pull Routing Architecture
Li, Yue; Saucez, Damien; Iannone, Luigi et al

in Proc. IEEE Workshop on Network Measurements (WNM) (2016, November)

Future Internet has been a hot topic for the last decade. One of the approaches put forward in order to revise the Internet architecture is LISP~--~Locator/ID Separation Protocol, which leverages the ... [more ▼]

Future Internet has been a hot topic for the last decade. One of the approaches put forward in order to revise the Internet architecture is LISP~--~Locator/ID Separation Protocol, which leverages the separation of the identifier and the locator roles of IP addresses. Contrary to the classical push model used by the BGP-based routing architecture, LISP relies on a pull model. In particular, routing information is pulled from a new network element, the Mapping System, to provide the association between the identifier (i.e., the address used to identify a host inside a domain) and a list of locators (i.e., the addresses to locate an attachment point) upon an explicit query. In this paper, we evaluate a LISP Mapping System deployment in the public LISP Beta Network from two standpoints: Stability and Consistency. Our measurements show that the mapping information is stable over time and consistent between the different mapping entities and the vantage points. Our analysis shows that there are cases where the Mapping System is unstable and/or inconsistent, hence, beside proposing a taxonomy in order to classify them, we carry out an in-depth investigation of such cases so to provide hints on how to improve the performance of LISP. [less ▲]

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See detailPreoptic glutamate and estradiol release during male sexual behavior
de Bournonville, Catherine ULg; de Bournonville, Marie-Pierre ULg; Aourz, Najat et al

Poster (2016, November)

Beside its long-term control by steroids, male sexual behavior is also modulated by neuroestrogens in a dynamic way (within minutes) in a number of species ranging from fishes to mammals. Studies in male ... [more ▼]

Beside its long-term control by steroids, male sexual behavior is also modulated by neuroestrogens in a dynamic way (within minutes) in a number of species ranging from fishes to mammals. Studies in male Japanese quail have also identified following exposure to a receptive female a rapid decrease in the activity of brain aromatase (AA) the enzyme responsible for the conversion of androgens into estrogens. These effects occur mainly within the medial preoptic nucleus (POM), a sexually dimorphic structure of the preoptic area that plays a key role in the activation of male sexual behavior and contains the highest AA in the brain. In vitro studies demonstrated that AA can be rapidly inhibited by calcium-dependent phosphorylations of the enzyme triggered by the activation of AMPA and kainate receptors. We confirmed here this rapid effect of glutamate on AA by injecting kainate in the POM of anesthetized males and measuring AA in the tissue after brain collection. AA in POM was inhibited in the kainate-injected hemisphere compared to the control hemisphere injected with vehicle. In a second experiment, we showed by in vivo microdialysis that glutamate is released in POM during copulation. These results thus suggest that glutamate controls dynamic changes of AA that occur in the brain during sexual interactions. To confirm that the decrease in AA leads to an actual reduction of local estradiol concentration, we quantified via microdialysis and radioimmunoassay changes in estradiol concentration in the male POM during sexual interactions with a female. Surprisingly, a dramatic elevation of estradiol was observed during copulation. Estradiol has been shown to enhance acutely male sexual motivation, therefore the function of its increase in the POM could be to maintain motivation during the entire sexual encounter. The decrease of AA observed ex vivo after copulation would then reflect a compensatory mechanism to restore baseline pre-copulatory conditions. Importantly, these results highlight that although long-term changes in AA are often used as a proxy for local estradiol concentrations, these two measures can show major short-term discrepancies possibly reflecting variations in estrogen turnover. [less ▲]

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