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See detailDiversity, dynamics and trophic ecology of animal communities associated to Posidonia oceanica (L.) Delile macrophytodetrital accumulation: synthesis of a ten year study
Lepoint, Gilles ULg; Borges, Alberto ULg; Champenois, Willy ULg et al

Poster (2016, October 17)

In the Mediterranean, Neptune grass Posidonia oceanica, produces a huge quantity of detrital biomass. These macrophytodetritus may accumulate in shallow waters, forming litter accumulations colonised by ... [more ▼]

In the Mediterranean, Neptune grass Posidonia oceanica, produces a huge quantity of detrital biomass. These macrophytodetritus may accumulate in shallow waters, forming litter accumulations colonised by abundant, yet understudied, animal communities. These accumulations are especially foraged by juvenile and adult fishes. Here, we aim to synthesize results obtained over the last ten years regarding diversity, dynamics and trophic ecology of associated meio- and macrofauna. Accumulations are found throughout the year but important seasonal and short-term variability in composition, quantity and physico-chemical parameters inside the accumulation is observed. Accumulations are dominated by respiration (litter degradation), however, primary production occurs at exposed surfaces (epiphytic production). Meio- and macrofauna have distinct traits in comparison to adjacent habitats (seagrass meadows or epilithic algae communities). A physico-chemical gradient occurs inside accumulations which partially defines assemblage composition and distribution. Meiofauna, in particular harpacticoid copepods, is diverse, abundant and composed of species from seagrass meadows, water column and sediment. In contrast, macrofaunal assemblages are simplified compared to the ones occurring in the seagrass meadows and are dominated by amphipods. Litter accumulations display a lower macrofaunal diversity than do seagrass meadows, but a higher abundance and animal biomass. Meio- and macrofauna show a high trophic diversity, dominated by ingestion and assimilation of epiphytes (macroalgae and, probably, detrivorous microbiota). Moreover, direct or indirect assimilation of carbon originating from seagrass detritus is demonstrated for many species. Although diverse trophic niches were observed, the assemblage showed a simplified trophic web structure compared to the seagrass meadows. Detritivorous organisms dominate this assemblage and are more abundant in the litter than in the living meadows. Consequently, according to its abundance and the fact it consumes directly and indirectly seagrass material, fauna associated to litter accumulation may play a significant role in the degradation and transfer to higher trophic level of detrital seagrass carbon. [less ▲]

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See detailThe closure of arteriovenous fistula in kidney transplant recipients is associated with an acceleration of kidney function decline
WEEKERS, Laurent ULg; VANDERWECKENE, Pauline ULg; pottel, hans et al

in Nephrology Dialysis Transplantation (2016)

ABSTRACT Background. The creation of arteriovenous fistula (AVF) may retard chronic kidney disease progression in the general population. Conversely, the impact of AVF closure on renal function in kidney ... [more ▼]

ABSTRACT Background. The creation of arteriovenous fistula (AVF) may retard chronic kidney disease progression in the general population. Conversely, the impact of AVF closure on renal function in kidney transplant recipients (KTRs) remains unknown. Methods. From 2007 to 2013, we retrospectively categorized 285 KTRs into three groups: no AVF (Group 0, n = 90), closed AVF (Group 1, n = 114) and left-open AVF (Group 2, n = 81). AVF closure occurred at 653 ± 441 days after kidney transplantation (KTx), with a thrombosis:ligation ratio of 19:95. Estimated glomerular filtration rate (eGFR) was determined using the Modification of Diet in Renal Disease equation. Linear mixed models calculated the slope and intercept of eGFR decline versus time, starting at 3 months post-KTx, with a median follow-up of 1807 days (95% confidence interval 1665–2028). Results. The eGFR slope was less in Group 1 (−0.081 mL/min/ month) compared with Group 0 (−0.183 mL/min/month; P = 0.03) or Group 2 (−0.164 mL/min/month; P = 0.09). Still, the eGFR slope significantly deteriorated after (−0.159 mL/min/month) versus before (0.038 mL/min/month) AVF closure (P= 0.03). Study periods before versus after AVF closure were balanced to a mean of 13.5 and 12.5 months, respectively, with at least 10 observations per patient (n = 99). Conclusions. In conclusion, a significant acceleration of eGFR decline is observed over the 12 months following the closure of a functioning AVF in KTRs. [less ▲]

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See detailHypogonadisme, Gynécomastie, Hirsutisme: sémiologie, diagnostic et prise en charge
VALDES SOCIN, Hernan Gonzalo ULg

Learning material (2016)

Le contrôle neuroendocrinien de la reproduction chez les mammifères est régi par un réseau de neurones hypothalamiques d'environ 1500 neurones à GnRH, qui modulent l’activité de l'axe de la reproduction ... [more ▼]

Le contrôle neuroendocrinien de la reproduction chez les mammifères est régi par un réseau de neurones hypothalamiques d'environ 1500 neurones à GnRH, qui modulent l’activité de l'axe de la reproduction au cours de la vie. Plus récemment on a décrit une modulation du générateur à GnrH par des neurones à GnIH, kisspeptines et neurokinin B. L'hypogonadisme hypogonadotrope se décline en acquis (post traumatisme cranien ou TBI, post radiothérapie, associé à des maladies métaboliques ou inflammatoires, etc) et hypogonadisme hypogonadotrope congénital (HHC). Le HHC est un syndrome clinique qui est caractérisé par une insuffisance pubertaire partielle ou complète. Le HH congénital peut résulter d'une insuffisance hypothalamique de la sécrétion/action du GnRH ou d'une insuffisance de sécrétion/effets des gonadotrophines hypophysaires LH et FSH. Chez l'homme, plusieurs gènes qui participent à l'olfaction et à la migration neuronale de GnRH interagissent pendant l’embryogénèse et le développement fœtal. Un nombre grandissant de mutations de ces gènes est responsable de l’ HH congénital. Basé sur la présence ou l'absence de troubles de l'olfaction, le HH est divisé en deux syndromes : HH avec anosmie/hyposmie (le syndrome de Kallmann) et l’ hypogonadisme hypogonadotrophique normosmique isolé (HHnI). Le syndrome de Kallmann (KS) est une maladie hétérogène qui affecte 1 personne sur 5000, avec 3 à 5 fois plus d’hommes que de femmes. Le KS est associé à des mutations de gènes qui sont principalement liées à des défauts de la migration neuronale. Ces défauts reproductifs et olfactifs comprennent un phénotype variable, y compris une surdité neurosensorielle, un colobome, des syncinéties controlatérales bimanuelles, des malformations crâniofaciales et une agénésie rénale. Fait intéressant, les mutations invalidantes de certains gènes responsables du KS : PROKR2, FGFR1, FGF8, CHD7, DUSP6 et WDR11, sont également associées à un hypogonadisme IHH normosmique, tandis que des mutations KISS1/KISSR, TAC3/TACR3, GNRH1/GNRHR, LEP/LEPR, HESX1, βFSH et βLH (syndrome de Pasqualini) ne sont présentes que chez les patients atteints de IHH normosmique. Dans ce cours destiné aux étudiants de Médecine (MASTER) de l'Ulg, nous exposons les aspects cliniques , physiopathologiques, les avancées génétiques et la prise en charge de l'hypogonadisme hypogonadotrope en pathologie humaine. Dans une deuxième partie, il sera discuté la sémiologie et prise en charge de la gynécomastie chez l'homme et l'hirsutisme chez la femme. [less ▲]

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See detailLe rôle de la compréhension de la notion de modèle dans la vision des futurs enseignants des sciences de la structure atomique
Karous, Hamad ULg; Nihant, Brigitte ULg; Leyh, Bernard ULg

Conference (2016, October 16)

Atomic theory is a key concept in science education. However, it was found that students often have difficulties in learning the fundamental notions of this theory. These difficulties reveal themselves in ... [more ▼]

Atomic theory is a key concept in science education. However, it was found that students often have difficulties in learning the fundamental notions of this theory. These difficulties reveal themselves in the expression of some preconceptions which tend to persist over time and thus may occur up to the higher education level. The goal of our study is to highlight some difficulties related to the notions of models and modelling notions and to illustrate the causes of appearance of such preconceptions. To do this, two questionnaires were submitted to future sciences teachers (chemistry, biology and physics) who did a training at the University of Belgium in 2014-2015 and in 2015-2016 (40> participants). The first questionnaire deals with the modelling concept and process while the second one is about the atomic model diagrams which illustrate many textbooks. Identifying the nature of the models and their construction may lead to misconceptions while acquiring basic scientific knowledge. [less ▲]

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See detailUne hypokaliémie à Liège
VALDES SOCIN, Hernan Gonzalo ULg; EMONTS, Patrick ULg; HAMOIR, Etienne ULg et al

Conference (2016, October 15)

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See detailLe régime disciplinaire appliqué aux internés : irresponsables au pénal, responsables au disciplinaire ?
Michiels, Olivier ULg; Nederlandt, Olivia

in Journal des Tribunaux (2016), (6660), 561-570

La loi de principes du 12 janvier 2005 organise un régime disciplinaire au sein des établissements pénitentiaires avec pour objectif le maintien de l'ordre et de la sécurité. Ce régime s'applique aux ... [more ▼]

La loi de principes du 12 janvier 2005 organise un régime disciplinaire au sein des établissements pénitentiaires avec pour objectif le maintien de l'ordre et de la sécurité. Ce régime s'applique aux internés détenus en prison. Déclarer des internés responsables d'avoir commis des infractions disciplinaires pose cependant question, dès lors que la mesure d'internement signifie qu'ils ont préalablement été déclarés irresponsables de leurs actes. Cet article présente le régime disciplinaire appliqué en prison, en abordant différentes questions relatives aux infractions disciplinaires, portant sur leur nature juridique, leur élément moral et leur imputabilité aux internés. [less ▲]

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See detailIs there a place for BTR markers in renal osteodystrophy?
DELANAYE, Pierre ULg

Conference (2016, October 15)

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See detailLe port de vêtements et symboles religieux sur les lieux de travail
Kéfer, Fabienne ULg

Article for general public (2016)

Un employeur peut-il interdire à ses travailleurs de porter des signes religieux sur leurs lieux de travail, et en particulier le foulard islamique? Cette question met en jeu la combination de plusieurs ... [more ▼]

Un employeur peut-il interdire à ses travailleurs de porter des signes religieux sur leurs lieux de travail, et en particulier le foulard islamique? Cette question met en jeu la combination de plusieurs libertés : la liberté de manifester sa religion, le droit de ne pas être traité de manière défavorable en raison de sa religion, la liberté d'entreprendre, qui permet à l'employeur de choisir l'image de marque de son entreprise, le droit des autres salariés de ne pas avoir de religion, etc. [less ▲]

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See detailHow to measure renal function?
DELANAYE, Pierre ULg

Conference (2016, October 14)

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See detail68Ga and 188Re Starch-Based Microparticles as Theranostic Tool for the Hepatocellular Carcinoma: Radiolabeling and Preliminary In Vivo Rat Studies
Verger, Elise ULg; Drion, Pierre ULg; MEFFRE, Geneviève ULg et al

in PLoS ONE (2016)

This work aims to develop, validate and optimize the radiolabeling of Starch-Based Microparticles (SBMP) by 188Re and 68Ga in the form of ready-to-use radiolabeling kits, the ultimate goal being to obtain ... [more ▼]

This work aims to develop, validate and optimize the radiolabeling of Starch-Based Microparticles (SBMP) by 188Re and 68Ga in the form of ready-to-use radiolabeling kits, the ultimate goal being to obtain a unique theranostic vector for the treatment of Hepatocellular Carcinoma. METHODS: Optimal labeling conditions and composition of freeze-dried kits were defined by monitoring the radiochemical purity while varying several parameters. In vitro stability studies were carried out, as well as an in vivo biodistribution as a preliminary approach with the intra-arterial injection of 68Ga radiolabeled SBMP into the hepatic artery of DENA-induced rats followed by PET/CT imaging. RESULTS: Kits were optimized for 188Re and 68Ga with high and stable radiochemical purity (>95% and >98% respectively). The in vivo preliminary study was successful with more than 95% of activity found in the liver and mostly in the tumorous part. CONCLUSION: SBMP are a promising theranostic agent for the Selective Internal Radiation Therapy of Hepatocellular carcinoma [less ▲]

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See detailSeasonal changes and steroid control of perineuronal nets in the song control system
Cornez, Gilles ULg; Shevchouk, Olesya ULg; Madison, Farrah et al

Conference (2016, October 14)

Perineuronal nets (PNNs) are aggregations of extracellular matrix components surrounding the soma of some neurons, mainly GABAergic interneurons expressing the calcium binding protein parvalbumin (PV ... [more ▼]

Perineuronal nets (PNNs) are aggregations of extracellular matrix components surrounding the soma of some neurons, mainly GABAergic interneurons expressing the calcium binding protein parvalbumin (PV+). In mammals, the development of PNNs limits synaptogenesis around PV+ neurons and PNNs have been validated as a marker characterizing the end of critical periods for some types of learning. In oscines, song learning is limited to critical periods either during ontogeny in close-ended learners such as zebra finches or during specific phases of the annual cycle in open-ended learners such as canaries or starlings. In zebra finches, PNN expression increases when the song crystalizes and this increase is markedly inhibited if juveniles are deprived from a tutor, which is known to delay the closure of the critical period for song learning. Nothing is known however about a possible role of PNNs in adult seasonal plasticity of open-ended learners. We compared PNNs expression and their colocalization with PV+ neurons in photosensitive, photostimulated, and photorefractory starlings. Although this treatment affected as expected the testes volumes, testosterone concentrations and volumes of song control nuclei, it did not markedly change the expression of PNNs or PV+ neurons in song control or auditory nuclei. In a second experiment, brains of female canaries implanted with testosterone for 1, 2, 9, or 21 days displayed an increase of the total numbers of PV+ neurons and PNNs in HVC, the total number of PNNs in nucleus robustusarcopallialis (RA), the density of PNNs in Area X and the %PV+ neurons surrounded by PNNs in RA and Area X. Interestingly the density of PNNs in song control nuclei progressively decreases from zebra finches to canaries to starlings in parallel with the increased song plasticity in these species supporting the notion that PNNs may limit brain and thus song plasticity in a species-typical manner. [less ▲]

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See detailLes xylanases : hier et demain ?
Beckers, Yves ULg

Conference given outside the academic context (2016)

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See detailMachine monstrueuse. Retour sur l'excès, l'exhibition et le gros plan
Jousten, Lison ULg

Conference (2016, October 14)

La communication propose de revenir sur certains aspects monstrueux du cinématographe. À la fois vectrice et créatrice d’un imaginaire intimement associé à la machine, il s’agit principalement d’envisager ... [more ▼]

La communication propose de revenir sur certains aspects monstrueux du cinématographe. À la fois vectrice et créatrice d’un imaginaire intimement associé à la machine, il s’agit principalement d’envisager comment cette « machine à voir » (Viva Paci, 2012) est aussi étroitement liée à la question de la monstruosité. [less ▲]

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See detailA full inference toolbox to measure multivariate relative dispersion
Aerts, Stéphanie ULg; Haesbroeck, Gentiane ULg

Conference (2016, October 14)

In the univariate context, coefficients of variation (CV) are widely used to compare the dispersion of a variable in several populations. When the comparison is based on p characteristics however, side-by ... [more ▼]

In the univariate context, coefficients of variation (CV) are widely used to compare the dispersion of a variable in several populations. When the comparison is based on p characteristics however, side-by-side comparison of marginal CV’s may lead to contradictions. In this talk, we present a multivariate coefficient of variation (MCV), defined as the inverse of the Mahalanobis distance between the mean and the origin, whose usefulness is demonstrated in some applications in finance and analytical chemistry. A full inference toolbox is provided for practitioners: several parametric and non-parametric bias-correction methods are suggested and compared, and some exact and approximate confidence intervals are built and analyzed in a simulation study. Finally, in order to meet the practical need to compare MCV’s in K populations, some asymptotic statistical testing procedures are derived, whose finite-sample performance is empirically assessed. Throughout the talk, the robustness of the techniques will be discussed. As a by-product, a test statistic allowing to reliably compare K univariate CV’s even in presence of outliers will be outlined. [less ▲]

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See detailAvis d’initiative sur l’impact du TTIP sur les pays en développement
Zacharie, Arnaud; Dos Santos Costa, Vera; Coheur, Alain et al

Article for general public (2016)

La nouvelle génération de traités sur le commerce et l’investissement négociés par l’Union européenne d’une part et les Etats-Unis (TTIP) et le Canada (CETA) d’autre part auraient un impact négatif sur ... [more ▼]

La nouvelle génération de traités sur le commerce et l’investissement négociés par l’Union européenne d’une part et les Etats-Unis (TTIP) et le Canada (CETA) d’autre part auraient un impact négatif sur les pays en développement. C’est pourquoi le CWBCI recommande aux parlements et aux gouvernements de la Région wallonne, de la Région bruxelloise, de la Fédération Wallonie-Bruxelles et de la Communauté germanophone de ne pas les ratifier. [less ▲]

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See detailTreg, Th17 and γδ T cells during normal and abortive pregnancy
Polese, Barbara ULg; Gridelet, Virginie ULg; Munaut, Carine ULg et al

Poster (2016, October 14)

Detailed reference viewed: 14 (3 ULg)