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See detailOvertopping induced failure of non-cohesive, homogenous fluvial dikes
Rifai, Ismail ULg; Erpicum, Sébastien ULg; Archambeau, Pierre ULg et al

in Water Resources Research (in press)

Accurate predictions of breach characteristics are necessary to reliably estimate the outflow hydrograph and the resulting inundation close to fluvial dikes. Laboratory experiments on the breaching of ... [more ▼]

Accurate predictions of breach characteristics are necessary to reliably estimate the outflow hydrograph and the resulting inundation close to fluvial dikes. Laboratory experiments on the breaching of sand-filled fluvial dikes were performed, considering a flow parallel to the dike axis. The breach was triggered by overtopping of the dike crest. A detailed monitoring of the transient evolution of the breach geometry was conducted, providing key insights into the gradual and complex processes involved in fluvial dike failure. The breach develops in two phases: (1) the breach becomes gradually wider and deeper eroding on the downstream side along the main channel, and (2) breach widening controlled by side slope failures, continuing in the downstream direction only. Increasing the inflow discharge in the main channel, the breach formation time decreases significantly and the erosion occurs preferentially on the downstream side. The downstream boundary condition has a strong influence on the breach geometry and the resulting outflow hydrograph. [less ▲]

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See detailHomo sacer, consecratio et destinatio dis
Berthelet, Yann ULg

in Lanfranchi, Thibaud (Ed.) Autour de la notion de sacer (in press)

Detailed reference viewed: 18 (2 ULg)
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See detailTempla de majesté et conception du vote à Rome
Berthelet, Yann ULg

in Virginie Hollard, et al. (Ed.) Le vote en Grèce et à Rome (in press)

Detailed reference viewed: 9 (2 ULg)
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See detailLes élections sacerdotales, sous la République romaine. Un exemple de politisation et de démocratisation ?
Berthelet, Yann ULg

in Hollard, Virginie; Le Digol, Christophe (Eds.) Histoire d'élection(s) (in press)

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See detailOutbreak investigations and molecular characterization of foot-and-mouth disease viruses circulating in southwest Niger
Kouato; Fana, EM; King, DP et al

in Transboundary and Emerging Diseases (in press)

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See detailLe droit de l’Union européenne face à l’économie collaborative
Van Cleynenbreugel, Pieter ULg

in Revue Trimestrielle de Droit Européen (in press), (3),

La présente contribution a pour objectif de proposer un état de lieux de l’incidence du droit de l’Union européenne sur le développement, la promotion et la règlementation de l’économie collaborative au ... [more ▼]

La présente contribution a pour objectif de proposer un état de lieux de l’incidence du droit de l’Union européenne sur le développement, la promotion et la règlementation de l’économie collaborative au sein du marché intérieur. Pour ce faire, cet article se divise en deux parties. Dans la première partie, le phénomène de l’économie collaborative ainsi que les approches réglementaires envisagées par les institutions de l’Union européenne pour mieux encadrer cette économie seront analysés. Nous soulignerons que l’Union européenne décide pour l’instant de ne pas proposer de nouveaux instruments de réglementation, préférant plutôt interpréter les instruments et dispositions déjà existants du droit de l’Union européenne. S’inscrivant dans cette approche, la deuxième partie de la contribution dressera une cartographie des dispositions pertinentes du droit de l’Union européenne qui gouvernent l’économie collaborative, en proposant des lignes directrices supplémentaires qui devraient permettre d’encore mieux intégrer l’économie collaborative dans le cadre juridique de l’Union européenne. [less ▲]

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See detailFree movement of goods
Van Cleynenbreugel, Pieter ULg; Van den Bogaert, Stefaan

in Ambtenbrink, Fabian; Curtin, Deirdre; De Witte, Bruno (Eds.) et al The Law of the European Union (in press)

This chapter offers a 60 pages overview of the case law on the free movement of goods. It detects the trends underlying the Court's case law and assembles all relevant data on the subject matter.

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See detailVIP: Vortex Image Processing package for high-contrast direct imaging
Gómez González, Carlos ULg; Wertz, Olivier; Absil, Olivier ULg et al

in Astronomical Journal (The) (in press)

We present the Vortex Image Processing (VIP) library, a python package dedicated to astronomical high-contrast imaging. Our package relies on the extensive python stack of scientific libraries and aims to ... [more ▼]

We present the Vortex Image Processing (VIP) library, a python package dedicated to astronomical high-contrast imaging. Our package relies on the extensive python stack of scientific libraries and aims to provide a flexible framework for high-contrast data and image processing. In this paper, we describe the capabilities of VIP related to processing image sequences acquired using the angular di↵erential imaging (ADI) observing technique. VIP implements functionalities for building high-contrast data processing pipelines, encompass- ing pre- and post-processing algorithms, potential sources position and flux estimation, and sensitivity curves generation. Among the reference point-spread function subtraction techniques for ADI post-processing, VIP includes several flavors of principal component analysis (PCA) based algorithms, such as annular PCA and incremental PCA algorithm capable of processing big datacubes (of several gigabytes) on a computer with limited memory. Also, we present a novel ADI algorithm based on non-negative matrix factorization (NMF), which comes from the same family of low-rank matrix approximations as PCA and provides fairly similar results. We showcase the ADI capabilities of the VIP library using a deep sequence on HR8799 taken with the LBTI/LMIRCam and its recently commissioned L-band vortex coronagraph. Using VIP we investigated the presence of additional companions around HR8799 and did not find any significant additional point source beyond the four known planets. VIP is available at http://github.com/vortex-exoplanet/VIP and is accompanied with Jupyter notebook tutorials illustrating the main functionalities of the library. [less ▲]

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See detailTonian (Neoproterozoic) eukaryotic and prokaryotic organic-walled microfossils from the upper Visingsö Group, Sweden
Loron, Corentin ULg; Moczydłowska, Małgorzata

in Palynology (in press)

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See detailChanges in biophysical membrane properties induced by the Budesonide/ Hydroxy-β-cyclodextrin complex
dos Santos, Andreia; Bayiha, Jules; Dufour, Gilles et al

in BBA Biomembranes (in press)

Budesonide (BUD), a poorly soluble anti-inflammatory drug, is used to treat patients suffering from asthma and COPD (Chronic Obstructive Pulmonary Disease). Hydroxypropyl-β-cyclodextrin (HPβCD), a ... [more ▼]

Budesonide (BUD), a poorly soluble anti-inflammatory drug, is used to treat patients suffering from asthma and COPD (Chronic Obstructive Pulmonary Disease). Hydroxypropyl-β-cyclodextrin (HPβCD), a biocompatible cyclodextrin known to interact with cholesterol, is used as a drug-solubilizing agent in pharmaceutical formulations. Budesonide administered as an inclusion complex within HPβCD (BUD:HPβCD) required a quarter of the nominal dose of the suspension formulation and significantly reduced neutrophil induced inflammation in a COPD mouse model exceeding the effect of each molecule administered individually. This suggests the role of lipid domains enriched in cholesterol for inflammatory signaling activation. In this context, we investigated the effect of BUD:HPβCD on the biophysical properties of membrane lipids. On cellular models (A549, lung epithelial cells), BUD:HPβCD extracted cholesterol similarly to HPβCD. On large unilamellar vesicles (LUVs), by using the fluorescent probes diphenylhexatriene (DPH) and calcein, we demonstrated an increase in membrane fluidity and permeability induced by BUD:HPβCD in vesicles containing cholesterol. On giant unilamellar vesicles (GUVs) and lipid monolayers, BUD:HPβCD induced the disruption of cholesterol-enriched raft-like liquid ordered domains as well as changes in lipid packing and lipid desorption from the cholesterol monolayers, respectively. Except for membrane fluidity, all these effects were enhanced when HPβCD was complexed with budesonide as compared with HPβCD. Since cholesterol-enriched domains have been linked to membrane signaling including pathways involved in inflammation processes, we hypothesized the effects of BUD:HPβCD could be partly mediated by changes in the biophysical properties of cholesterol-enriched domains. [less ▲]

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See detailPharmacokinetic characterization of [18F]UCB-H PET radiopharmaceutical in the rat brain.
Becker, Guillaume ULg; Warnier, Corentin; Serrano Navacerrada, Maria Elisa ULg et al

in Molecular Pharmaceutics (in press)

The synaptic vesicle glycoprotein 2A (SV2A), a protein essential to the proper nervous system function, is found in presynaptic vesicles. Thus, SV2A targeting, using dedicated radiotracers combined with ... [more ▼]

The synaptic vesicle glycoprotein 2A (SV2A), a protein essential to the proper nervous system function, is found in presynaptic vesicles. Thus, SV2A targeting, using dedicated radiotracers combined with positron emission tomography (PET), allows the assessment of synaptic density in the living brain. The first-in-class fluorinated SV2A specific radioligand, [18F]UCB-H, is now available at high-activity through an efficient radiosynthesis compliant with the current good manufacturing practices (cGMP). We report here a non-invasive method to quantify [18F]UCB-H binding in rat brain with microPET. Validation study in rats confirmed the need of high enantiomeric purity to target SV2A in vivo. We demonstrated the reliability of a population-based input function to quantify SV2A in preclinical microPET setting. Finally, we investigated the in vivo metabolism of [18F]UCB-H and confirmed the negligible amount of radiometabolites in the rat brain. Hence, the in vivo quantification of SV2A using [18F]UCB-H microPET seems a promising tool for the assessment of the synaptic density in the rat brain, and opens the way for longitudinal follow-up in neurodegenerative diseases rodents’ models. [less ▲]

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See detailJavier Cercas, Le mobile
Licata, Nicolas ULg

E-print/Working paper (2018)

Synopsis d'une nouvelle de Javier Cercas intitulée Le mobile (1987), rédigé dans le cadre du dossier "Les lectures pour l'été 2017" de la revue Culture.

Detailed reference viewed: 22 (1 ULg)
See detailSchizophrénie et perspective en première personne
Englebert, Jérôme ULg; Valentiny, Caroline

Scientific conference (2018, February 28)

Detailed reference viewed: 15 (3 ULg)
See detailLe travailleur du futur et la loi
Kéfer, Fabienne ULg

Conference given outside the academic context (2018)

Le travailleur du futur et la loi A quoi ressemble le travailleur de demain dans un monde où règnent toujours davantage les technologies de l’information ? Cette question est envisagée sous deux angles ... [more ▼]

Le travailleur du futur et la loi A quoi ressemble le travailleur de demain dans un monde où règnent toujours davantage les technologies de l’information ? Cette question est envisagée sous deux angles. Tout d’abord, l’économie numérique a fait naitre de nouvelles formes de production et d’emploi, telles que « l’économie des plateformes » (Uber, Deliveroo, ….). Celle-ci présente divers atouts pour les entreprises et pour les travailleurs, notamment en termes de flexibilité, mais elles est aussi la source de nouvelles formes de travail précaire. Le travailleur de demain est-il un travailleur du numérique sans protection sociale ? Le deuxième angle est celui du travailleur hyperconnecté. Faut-il envisager de créer un droit à la déconnexion ? [less ▲]

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See detailPartenariats transrégionaux, technologies numériques et culture : de la convergence numérique aux divergences normatives
Vlassis, Antonios ULg

in Deblock, Chrstian; Levesque, Céline; Paquin, Stephane (Eds.) et al Les partenariats commerciaux à l'ére de l'interconnexion (2018)

Detailed reference viewed: 22 (1 ULg)
See detailPsychopathologie du sens commun
Englebert, Jérôme ULg; Recchia, Fabio ULg

Book published by Cercle Herméneutique (Le) (2018)

Traduction en français et présentation de "Psicopatologia del senso commune" de Giovanni Stanghellini.

Detailed reference viewed: 49 (8 ULg)
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See detailFrom Ontology to Psychoanalysis. Benussi and Musatti on the Concept of Mental Reality
Boccaccini, Federico ULg

in Meinong Studies / Meinong Studien (2018), 9

Detailed reference viewed: 24 (0 ULg)
See detailL'Oeil de la mouche d'André-Joseph Dubois
Dechene, Antoine ULg

in Deux siècles au service des sciences humains: contributions de l'Université de Liège (1817-2017) (2018)

Detailed reference viewed: 22 (0 ULg)