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See detailLymphatic microcirculation
QUATRESOOZ, Pascale ULg

in Measuring the skin (in press)

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See detailChitosan-coated electrospun nanofibers with antibacterial activity
Croisier, Florence ULg; Sibret, Pierre ULg; Dupont-Gillain, Christine C. et al

in Journal of Materials Chemistry B (in press)

Charged nanofibers were prepared by electrospinning (ESP) poly(ε-caprolactone) with a copolymer bearing carboxylic acid functions. The presence of these functions allowed exposing some negative charges on ... [more ▼]

Charged nanofibers were prepared by electrospinning (ESP) poly(ε-caprolactone) with a copolymer bearing carboxylic acid functions. The presence of these functions allowed exposing some negative charges on the fiber surface, by dipping the fibers in a phosphate buffer. A layer of chitosan, a polycation in acidic medium, was then deposited on the nanofiber surface, thanks to electrostatic attraction. Fibers were characterized at each step of the process and the influence of the copolymer architecture on chitosan deposition was discussed. The antibacterial activity of the resulting fibers was finally assessed. [less ▲]

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See detailThe materiality of Intangible Cultural Heritage: food and social encounters.
Mescoli, Elsa ULg

in AA.VV. (Ed.) Procedings of SHARING CULTURES 2015 - 4th International Conference on Intangible Heritage (in press)

Following the patrimonialization process of the Mediterranean diet, some gastronomies found themselves involved within a common framework of food traditions. Some regional practices, indicated as ... [more ▼]

Following the patrimonialization process of the Mediterranean diet, some gastronomies found themselves involved within a common framework of food traditions. Some regional practices, indicated as representative of national food cultures, were chosen to illustrate a shared heritage that historically took a shape around the Mediterranean sea. This heritage, still concretely performed, needed to be stated and preserved against the globalization of food practices. Institutional and political dynamics, occurring on a transnational level, triggered this process, which is nevertheless not detached from the communities involved. Common people played a fundamental role not only in promoting the patrimonialization process itself, but above all in concretely perpetuating some traditions and in spreading them in the contemporary world. In particular, some different cultural groups that found themselves living a common territory and social context thanks to migration, began dialoguing about their own food traditions, starting from some shared elements. As a consequence, some gastronomies interact through people’s practices and define in relation one to the other. This is the case, among others, of Moroccan and Italian cuisine. Throughout a doctoral research conducted within a group of Moroccan women living in the North of Italy, I collected an amount of ethnographic materials showing how social encounters developed through food. The influence of the patrimonialization process on these encounters made people try to find similarities among different traditional practices or to describe some ways of reinterpreting them in reason of the new context. My presentation will focus on these dynamics, thus proving that the Intangible Cultural Heritage is indeed grounded on materiality, that is, in this case, the concrete performance of food practices and their pragmatic effects on relations among humans. [less ▲]

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See detailInfluence of past and future climate changes on the distribution of three Southeast Asian murine rodents
Latinne, Alice ULg; Meynard, Christine; Herbreteau, Vincent et al

in Journal of Biogeography (in press)

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See detailA radio-map of the colliding winds in the very massive binary system HD93129A
Benaglia, Paula; Marcote, Benito; Moldon, Javier et al

in Astronomy and Astrophysics (in press)

Radio observations are an effective tool to discover particle acceleration regions in colliding-wind binaries, through detection of synchrotron radiation; these regions are natural laboratories for the ... [more ▼]

Radio observations are an effective tool to discover particle acceleration regions in colliding-wind binaries, through detection of synchrotron radiation; these regions are natural laboratories for the study of relativistic particles.Wind-collision region (WCR) models can reproduce the radio continuum spectra of massive binaries that contain both thermal and non-thermal radio emission; however, key constraints for models come from high-resolution imaging. Only five WCRs have been resolved to date at radio frequencies at milliarcsec (mas) angular scales. The source HD93129A, prototype of the very few known O2 I stars, is a romising target for study: recently, a second massive, early-type star about 50 mas away was discovered, and a non-thermal radio source detected in the region. Preliminary long-baseline array data suggest that a significant fraction of the radio emission from the system comes from a putative WCR. We sought evidence that HD93129A is a massive binary system with colliding stellar winds that produce non-thermal radiation, through spatially resolved images of the radio emitting regions. Methods.We completed observations with the Australian Long Baseline Array (LBA) to resolve the system at mas angular resolutions and reduced archival Australia Telescope Compact Array (ATCA) data to derive the total radio emission. We also compiled optical astrometric data of the system in a homogeneous way. We reduced historical Hubble Space Telescope data and obtained absolute and relative astrometry with milliarcsec accuracy. The astrometric analysis leads us to conclude that the two stars in HD93129A form a gravitationally bound system. The LBA data reveal an extended arc-shaped non-thermal source between the two stars, indicative of a WCR. The wind momentum-rate ratio of the two stellar winds is estimated. The ATCA data show a point source with a change in flux level between 2003-4 and 2008-9, that is modeled with a non-thermal power-law spectrum with spectral indices of - 1:03 +/- 0:09 and -1:21 +/- 0:03 respectively. The mass-loss rates derived from the deduced thermal radio emission and from the characteristics of the WCR are consistent with estimates derived by other authors. [less ▲]

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See detailLe marché des radicaux libres. Sur quelques conditions médiatiques de la posture « néo-réactionnaire ».
Durand, Pascal ULg

in Quaderni : la Revue de la Communication (in press)

Years 1990-2000 could be characterized in France by the emergence of a current of thought and a nebula of intellectual actors collectively gathered under the label of the « New Reactionaries » since the ... [more ▼]

Years 1990-2000 could be characterized in France by the emergence of a current of thought and a nebula of intellectual actors collectively gathered under the label of the « New Reactionaries » since the publication of the controversial pamphlet, Le Rappel à l’ordre, by Daniel Lindenberg in 2002. Journalists, novelists, essayists, columnists, philosophers, showing a posture of refusal towards the « politically correct », the « moral left » and the « dominant ideology », they can be viewed as a kind of generic character, made up of peculiarities breaking away from any sociological assignment. The topics of this discourse tends to be analyzed from a point of view not included within the concerned polemical filed. The aim of this paper is to contribute to such an analysis by pointing out the transformations of the journalistic and publishing field from which the « new reactionaries » draw some of their powerful polemical efficiency. [less ▲]

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See detailUsing platelet-rich plasma to treat jumper's knees: Exploring the effect of a second closely-timed infiltration
Kaux, Jean-François ULg; Croisier, Jean-Louis ULg; Forthomme, Bénédicte ULg et al

in Journal of Science and Medicine in Sport (in press)

Some clinical series have evaluated the effect of platelet-rich plasma (PRP) in the treatment of proximal patellar tendinopathy. Although it is possible that a single infiltrative administration may prove ... [more ▼]

Some clinical series have evaluated the effect of platelet-rich plasma (PRP) in the treatment of proximal patellar tendinopathy. Although it is possible that a single infiltrative administration may prove to be an effective treatment for this indication, most of the existing studies evaluated the effects of two or three successive infiltrations. The aim of this study was to evaluate whether two infiltrations of PRP proves more effective than a single treatment. DESIGN: Prospective, randomized and comparative study of level 2. METHODS: Twenty patients suffering from chronic proximal patellar tendinopathy were enrolled into the study and split into two randomized groups (one or two infiltrations of PRP, respectively). The 3-month follow-up evaluation consisted of VAS, IKDC and VISA-P scores, along with algometer, isokinetic and ultrasounds evaluations. After 1 year, subjects were contacted to define their functional evolution. RESULTS: The concentration of the PRP used for each infiltration was similar in both groups, and contained no red or white cells. Results revealed no difference in treatment efficacy between the groups. CONCLUSIONS: The comparison between one or two infiltrations of PRP did not reveal any difference between the two groups at short to mid term. A second closely-timed infiltration of PRP to treat proximal patellar tendinopathies is not necessary to improve the efficacy of this treatment in the short term. [less ▲]

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See detailExploring the Interest in and the Usage of the Internet Among Patients Eligible for Osteoporosis Screening.
Slomian, Justine ULg; Reginster, Jean-Yves ULg; Gaspard, Ulysse ULg et al

in Calcified tissue international (in press)

The aim of this study was to evaluate the interest in the Internet and its usage for health-related issues among people eligible for osteoporosis screening. Self-administered questionnaires have been ... [more ▼]

The aim of this study was to evaluate the interest in the Internet and its usage for health-related issues among people eligible for osteoporosis screening. Self-administered questionnaires have been distributed to subjects who were screened for osteoporosis and to menopausal women. 177 patients have responded to the survey (64.5 +/- 10.1 years, 88.1 % of women). There are 78.5 % of Internet users. Among them, 67.2 % said searching information about their health and 74.5 % said using the Internet for this purpose. All respondents attributed an average score, out of 10, of 5.7 +/- 2.3 regarding the reliability of information that they could find on the Internet. The use of the Internet differs significantly depending on age: those who use the Internet are younger (62.1 +/- 8.91 years) than those who do not use it (73.3 +/- 9.42 years). The socioeconomic status also has an impact on the Internet use: Internet users have a higher education, are more professionally active and have a higher net monthly household income compared to the group of non-users. Even if age and socioeconomic status appear to be determining factors in the use of the Internet for the search of health information in patients eligible for osteoporosis screening, almost 75 % of the study population use the Internet for this purpose. Action to promote health through an Internet platform must therefore take these parameters into account. [less ▲]

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See detailNewt life after fish introduction: extirpation of paedomorphosis in a mountain fish lake and newt use of satellite pools
Denoël, Mathieu ULg; Scime, Patrick; Zambelli, Nicola

in Current Zoology (in press), 62

Fish introduction is one of the main causes of amphibian decline worldwide. It affects particularly rare aquatic phenotypes such as paedomorphs, which retain gills during the adult stage. In this context ... [more ▼]

Fish introduction is one of the main causes of amphibian decline worldwide. It affects particularly rare aquatic phenotypes such as paedomorphs, which retain gills during the adult stage. In this context, we determined whether small wetlands, such as pools surrounding fished and fishless lakes, could sustain paedomorphic and metamorphic newts. To this end, we surveyed lakes known historically to sustain Alpine newts (Ichthyosaura alpestris) as well as 35 nearby pools. On the basis of the published records, the only known population exhibiting paedomorphosis in the Swiss Alps was found to be extirpated by salmonid introductions. However, the metamorphs persisted in peripheral pools, paedomorphosis was discovered at a new locality, and overwintering larvae were still present in one of the lakes. These results show the importance of conserving varied aquatic habitats such as pools in mountainous environments where the main resources can become unsuitable for amphibians because of fish introductions. Pools may also function as reservoirs in maintaining newt populations until programs to remove fish from lakes can be carried out. It is not known if paedomorphs could reappear after fish removal. However, the combined resilience of amphibians after fish removal and the genetic basis for paedomorphosis highlighted in other taxa by previous studies suggest that there is the potential to maintain this intraspecific case of diversity even after its disappearance. [less ▲]

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See detailCarcinogenic HPV infection in the cervical squamo-columnar junction
Mirkovic, Jelena; Howitt, Brooke; RONCARATI, Patrick ULg et al

in Journal of Pathology (The) (in press)

Recent studies have suggested the involvement of a unique population of cells at the cervical squamo-columnar junction (SCJ) in the pathogenesis of early (squamous intraepithelial lesion or SIL) and ... [more ▼]

Recent studies have suggested the involvement of a unique population of cells at the cervical squamo-columnar junction (SCJ) in the pathogenesis of early (squamous intraepithelial lesion or SIL) and advanced (squamous cell and adeno-carcinomas) cervical neoplasia. However, there is little evidence to date showing that SCJ cells harbour carcinogenic HPV or are instrumental in the initial phases of neoplasia. This study was designed to 1) determine if normal-appearing SCJ cells contained evidence of carcinogenic HPV infection and 2) trace their transition to early SIL. Sections of cervix from high-risk reproductive age women were selected and SCJ cells were analyzed by using several techniques which increasingly implicated HPV infection: HPV DNA (genotyping and in situ hybridization)/RNA (PCR), immunostaining for HPV16 E2 (an early marker of HPV infection), p16ink4, Ki67 and HPV L1 protein. In 22 cases with a history of SIL and no evidence of preneoplastic lesion in the excision specimen, HPV DNA was isolated from 8 of 10 with visible SCJ cells, 6 of which were HPV16/18 DNA positive. In 5 of these latter cases, the SCJ cells were positive for p16ink4 and/or HPV E2. Transcriptionally active HPV infection (E6/E7 mRNAs) was also detected in micro-dissected SCJ cells. Early squamous atypia associated with the SCJ cells demonstrated in addition diffuse p16ink4 immunoreactivity, elevated proliferative index and rare L1 antigen positivity. We present for the first time direct evidence that normal-appearing SCJ cells can be infected by carcinogenic HPV. They initially express HPV E2 and their progression to SIL is heralded by an expanding metaplastic progeny with increased proliferation and p16ink4 expression. Whether certain SCJs are more vulnerable than others to carcinogenic HPV genotypes and what variables determine transition to high grade SIL remain unresolved, but the common event appears to be a vulnerable cell at the SCJ. [less ▲]

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See detailA serious LAT relationship or a crazy machine? Metaphors in citizens’ perception of Belgian federalism
Perrez, Julien ULg; Reuchamps, Min

in Mots. Les Langages du Politique (in press)

This paper proposes a quantitative and qualitative corpus-based analysis of the use of metaphors in political discourse from the original perspective of citizen discourse. Our data were collected from ... [more ▼]

This paper proposes a quantitative and qualitative corpus-based analysis of the use of metaphors in political discourse from the original perspective of citizen discourse. Our data were collected from focus group discussions respectively held in the French-speaking and Dutch-speaking parts of Belgium, which tackled the citizens’ perceptions of Belgian federalism. Our findings suggest that citizens do produce metaphors when talking about complex political processes and that these metaphors reveal different political visions. This research also suggests differences in saliency of the source domains in terms of which citizens make sense of Belgian federalism. In this regard, the family domain, and more especially the metaphor BELGIAN FEDERALISM IS A LOVE RELATIONSHIP appears to function as an important conceptual reference point for the citizens’ understanding of the political relations in the Belgian context. [less ▲]

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See detailEpreuves de crédibilité du "citoyen-expert" dans un processus décisionnel. "Il peut", "il sait", "il argumente"
Parotte, Céline ULg; Piet, Grégory; Rossignol, Nicolas ULg

in Fourniau, Jean-Michel; Neveu, Catherine; Monnoyer-Smith, Laurence (Eds.) Démocratie, pour quoi faire? (in press)

Si les mécanismes de démocratie participative sont de plus en plus souvent convoqués au cœur de nos systèmes de démocratie représentative (Sintomer, Blondiaux, 2002), devons-nous considérer de facto que ... [more ▼]

Si les mécanismes de démocratie participative sont de plus en plus souvent convoqués au cœur de nos systèmes de démocratie représentative (Sintomer, Blondiaux, 2002), devons-nous considérer de facto que le citoyen a une influence dans le processus décisionnel? La participation est-elle le moyen de rendre légitime le rôle et le poids du citoyen dans le processus décisionnel ou a contrario est-elle un moyen supplémentaire pour l’autorité publique de renforcer la légitimité de son action, indépendamment des attentes du citoyen ? Si ce dernier n’était pas légitime, pourrait-il être crédible ? Sur base d’une analyse comparative de cinq conflits d’implantation, nous établirons que, d’une part, l’impératif délibératif (Sintomer, Blondiaux, 2002) est traversé par une logique d’action symbolique envers le citoyen (autrement dit, légitimer le processus par sa présence) et une logique d’intérêts des acteurs, en particulier, l’autorité publique. Confronter à cette double logique, nous proposerons de mettre en exergue les différentes formes d’appropriation de la participation par le citoyen [less ▲]

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See detailThe “Belgian Tetris”: Assessing the political impact of metaphors on citizens’ representations of Belgian federalism
Perrez, Julien ULg; Reuchamps, Min

in Metaphor and the Social World (in press)

Based on the idea that metaphors do not only reflect the perceived reality, but also function as cues through which citizens come to understand complex political processes, the aim of this study is to ... [more ▼]

Based on the idea that metaphors do not only reflect the perceived reality, but also function as cues through which citizens come to understand complex political processes, the aim of this study is to look at how specific metaphors might impact on the citizens' framing of Belgian federalism. To measure the impact of metaphors on the citizens' political representations, we conducted an experiment among 493 citizens based on an article published in the newspaper Le Soir in which Belgian federalism was compared to a Tetris game in both a text and an image. The participants were distributed into four experimental conditions according to the type of input they had been exposed to (text and image, text only, image only, no input) and were asked to perform a free description task. The productions of the participants were analyzed using keyword analyses and content analyses. The results suggest that the participants who had been exposed to the experimental text tend to differently frame their perception of Belgian federalism. These results show that reading the text, more than looking at the image, has an impact on the representations of the citizens but that this impact is short-lived. [less ▲]

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See detailSpecial issue on the political impact(s) of metaphors: Introduction
Perrez, Julien ULg; Reuchamps, Min

in Metaphor and the Social World (in press)

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See detailAn Ant Colony System for Responsive Dynamic Vehicle Routing
Schyns, Michael ULg

in European Journal of Operational Research (in press)

We present an algorithm based on an Ant Colony System to deal with a broad range of Dynamic Capacitated Vehicle Routing Problems with Time Windows, (partial) Split Delivery and Heterogeneous fleets ... [more ▼]

We present an algorithm based on an Ant Colony System to deal with a broad range of Dynamic Capacitated Vehicle Routing Problems with Time Windows, (partial) Split Delivery and Heterogeneous fleets (DVRPTWSD). Besides the traditional distance criterion, we address the important case of responsiveness. Responsiveness is defined here as completing a delivery as soon as possible, within the time window, such that the client or the truck may restart its activities. This is crucial for many production or service activities in different fields: express parcel deliveries, taxi services, Just in Time production, express repair services, medical care, petrol station replenishment, etc. We develop an interactive web-based solution to allow dispatchers to take new information into account in real-time. The algorithm and its parametrization were tested on real and artificial instances. We first illustrate our approach with a problem submitted by Liege Airport, the 8th biggest cargo airport in Europe. The goal is to develop a decision system to optimize the journey of the refueling trucks. We then consider some classical VRP benchmarks with extensions for more complex problems. [less ▲]

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See detailDe Rome à Wilderen : Alexandre Ier et Raoul de Saint-Trond
Schmidt, Kevin ULg

in Revue Belge de Philologie et d'Histoire (in press)

While Rudolf, the abbot of Sint-Truiden (1108-1138) was forced to abandon his monastery in 1121 after having opposed the claim to power of the future prince-bishop of Liège, Alexandre I (1128-1135), both ... [more ▼]

While Rudolf, the abbot of Sint-Truiden (1108-1138) was forced to abandon his monastery in 1121 after having opposed the claim to power of the future prince-bishop of Liège, Alexandre I (1128-1135), both men hastily set out for Rome on the eve of 1129, in order to meet Pope Honorius the Second. The Gesta abbatum Trudonensium have preserved this colorful account of the perilous circumstances under which they crossed the Great St. Bernard Pass together in full winter. Starting from this particular anecdote, the document, which recounts the evolving personal relationship between the bishop of Liège, Alexandre I and abbot Rudolf of Sint-Truiden, returns to the circumstances surrounding this surprising rapprochement, which came to pass against all expectations. It seeks to demonstrate that Rudolf of Sint-Truiden’s motivations to accompany his former enemy to Italy were political rather than spiritual. [less ▲]

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See detailDUSP3 genetic deletion confers M2-like−macrophage-dependent tolerance to septic shock
Singh, Pratibha; Dejager, Lien; Amand, Mathieu ULg et al

in Journal of Immunology (in press)

DUSP3 is a small dual-specificity protein phosphatase with an unknown physiological function. We report that DUSP3 is strongly expressed in human and mouse monocytes and macrophages and that its ... [more ▼]

DUSP3 is a small dual-specificity protein phosphatase with an unknown physiological function. We report that DUSP3 is strongly expressed in human and mouse monocytes and macrophages and that its deficiency in mice promotes tolerance to lipopolysaccharide (LPS)-induced endotoxin shock and to polymicrobial septic shock following cecal ligation and puncture. By using adoptive transfer experiments, we demonstrate that resistance to endotoxin is macrophage-dependent and transferable and that this protection is associated with a striking increase of M2-like macrophages in DUSP3-/- mice in both the LPS and cecal ligation and puncture models. We show that the altered response of DUSP3-/- mice to sepsis is reflected in decreased TNF production and impaired ERK1/2 activation. Our results demonstrate that DUSP3 plays a key and non-redundant role as a regulator of innate immune responses by mechanisms involving the control of ERK1/2 activation, TNF secretion and macrophage polarization. [less ▲]

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See detailGenetic determinants of Crohn’s disease and ulcerative colitis phenotypes in 34,819 patients.
Cleynen, Isabelle; Boucher, Gabrielle; Jostins, Luke et al

in Lancet (in press)

Detailed reference viewed: 6 (0 ULg)