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See detailFACILITER L'ADHÉRENCE AU TRAITEMENT IMMUNOSUPPRESSEUR CHEZ LES TRANSPLANTÉS DU REIN- TEST D'UN SYSTEME DE COACHING PAR SMARTPHONE
Saint-Remy, Annie ULg; Spiroux, Marie; WEEKERS, Laurent ULg et al

Poster (2016, December 08)

Facilitate adherence to immunosuppressive treatment in kidney transplant recipients – test of a coaching system with smartphone application A.Saint-Remy, M. Spiroux, L. Weekers, C. Bonvoisin, JM ... [more ▼]

Facilitate adherence to immunosuppressive treatment in kidney transplant recipients – test of a coaching system with smartphone application A.Saint-Remy, M. Spiroux, L. Weekers, C. Bonvoisin, JM. Krzesinski Introduction: Nonadherence to immunosuppressants is a determining cause of graft loss. The present study tested during 1 month, the usefulness and the effectiveness of a coaching system using smartphone application (the Transplant Smartcoach®) on adherence in kidney transplant recipients. Methodology: The sample included 51 patients (28m/23w) transplanted for 1 year at least, mean age 52±12 years, mean graft survival 3.7±1 years. Each patient had a smartphone configured with its detailed treatment. Using the smartphone application, patient had to notify daily the intake of each tablet into a 2-hour window. If no notification was performed 1 hour later than the scheduled time of intake, the patient was contacted by a nurse to remind him to take medications. Results: 90 % of patients were treated with Tacrolimus and 10 % with cyclosporine, associated with mycophenolic acid (41 %) or mycophenolate mofetil (49 %), 41 % had corticosteroids. Whatever was the immunosuppressant, a perfect adherence (medications taken at the scheduled time) was observed on average in 53 % of the morning monthly intakes. There was no difference in adherence rates between the morning intakes of Advagraf ® (once/day) and Prograft® (2 times/day), a decrease of perfect adherence was identified with the evening intake of Prograft® (53 % vs 44%; P=0.07) and the one of Myfortic® (P=0.03) with consequently an increased frequency of nurse’s recalls. Adherence was lower in younger patients and in those still working. The complexity of treatment (many drugs intake/day) and the respect for time intervals between drug intakes were the major barriers to adherence. When compared to the one measured before using the Smartcoach, the variability (coefficient of variation, %) of the Tacrolimus trough level decreased by 32.6 % (P=0.027) in the 3 to 6 months following the test. Conclusion: patients appreciated the ease and usefulness of the coaching system with smartphone application to help medication adherence. Coupled with therapeutic education of the patients, that tool deserves to be used notably in newly transplanted patients and when a worrying decrease in adherence is observed to help them in the management of a rigorous adherence which should contribute to graft survival. [less ▲]

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See detailL’Assurance Qualité dans un laboratoire
Marini Djang'Eing'A, Roland ULg; Widart, Joëlle ULg; Hubert, Philippe ULg

Learning material (2016)

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See detailExplorer la variation graphique dans les sources hiératiques de l’époque ramesside : Le scribe Amennakhte, sa main, son école
Polis, Stéphane ULg

Scientific conference (2016, December 07)

L'exposé est articulé en trois parties. Il s'ouvre sur un typologie de la variation dans les sources hiératiques du Nouvel Empire et vise à explorer les causes de cette dernière. Après quelques éléments ... [more ▼]

L'exposé est articulé en trois parties. Il s'ouvre sur un typologie de la variation dans les sources hiératiques du Nouvel Empire et vise à explorer les causes de cette dernière. Après quelques éléments de contextualisation concernant la communauté des ouvriers de la Tombe à Deir el-Médineh, la seconde partie est consacrée, d'une part, à la question de la construction de la norme - entre enseignement collectif et apprentissage individuel - et, d'autre part, à la diversité de la performance écrite (à travers l'examen de textes littéraires produits par Amennakhte et son ‘école’). En conclusion, je présente trois cas illustrant des voies fructueuses dans l'identification des mains de scribes et le regroupement de documents sur base paléographique. [less ▲]

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See detailOpen Access: challenging the norm in academia
Rentier, Bernard ULg

Conference (2016, December 07)

Science communication is undergoing a considerable evolution in the Internet era. Open Access is at last letting researchers, scholars and students in developing countries acquire full access to ... [more ▼]

Science communication is undergoing a considerable evolution in the Internet era. Open Access is at last letting researchers, scholars and students in developing countries acquire full access to scientific knowledge. Nowadays, this represents a bit less than half of the scientific literature, the other half being still hidden behind paywalls and unaffordable by them. Unfortunately, in order to preserve their highly profitable business model, the major publishing companies are flipping the model from "pay to read" to "pay to publish". This is the most important threat for African and other developing countries: the price to pay for reading freely is the loss of opportunity to communicate. A truly democratic future, at the international level, calls for publicly run open publication platforms accessible to all, submitted to open reviewing and immediately accessible. This novel communication tool can only be attractive upon two conditions: 1) it must be attractive enough so that the researchers become aware of the advantages it provides in terms of audience, visibility and potential citations; 2) the research/researcher evaluation processes must take the new paradigm in consideration and quit using the current indirect metrics (proxys) such as the journals impact factor. However, this indispensable change in the evaluation tradition must be adopted worldwide and at the same time if no scientific community, particularly the young generation, is to be sacrificed. [less ▲]

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See detailCorrecting circulation biases in a lower-resolution global general circulation model with data assimilation
Canter, Martin ULg; Barth, Alexander ULg; Beckers, Jean-Marie ULg

in Ocean Dynamics (2016)

In this study, we aim at developing a new method of bias correction using data assimilation. This method is based on the stochastic forcing of a model to correct bias by directly adding an additional ... [more ▼]

In this study, we aim at developing a new method of bias correction using data assimilation. This method is based on the stochastic forcing of a model to correct bias by directly adding an additional source term into the model equations. This method is presented and tested first with a twin experiment on a fully controlled Lorenz ’96 model. It is then applied to the lower-resolution global circulation NEMO-LIM2 model, with both a twin experiment and a real case experiment. Sea surface height observations are used to create a forcing to correct the poorly located and estimated currents. Validation is then performed throughout the use of other variables such as sea surface temperature and salinity. Results show that the method is able to consistently correct part of the model bias. The bias correction term is presented and is consistent with the limitations of the global circulation model causing bias on the oceanic currents. [less ▲]

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See detailGenetic diagnosis and emergence of patients and relatives' evidence-based activism
Duysens, Fanny ULg

Conference (2016, December 07)

Health- and disease-related events may be of highly significance for patients and their relatives. Naming a medical diagnosis is one of them. It carries the inherent power of (re)configuring the ... [more ▼]

Health- and disease-related events may be of highly significance for patients and their relatives. Naming a medical diagnosis is one of them. It carries the inherent power of (re)configuring the individuals' life courses, which are moreover closely linked to those of their relatives, and especially blood families in the case of (hereditary) genetic diseases. Drawing on ethnographic observations and narratives from patients and relatives involved in some Belgian organizations concerned with genetic disorders, this paper is interested in the ways these concerned people make sense of the naming of a medical diagnosis event by (re)interpreting their past familial stories, trying to intervene in the present, and designing a desired future. Then, it explores the case of the annual charity TV show "Téléthon", which is an initiative launched at the initiative of some French-speaking patients’ organizations (POs) concerned with neuromuscular disorders in the aims at putting awareness on rare disorders and raising funds in order to support biomedical research, especially in the field of medical genetics. The point is to question the dynamic relationships between the individual and familial experiences and such collective mobilizations, that is to say the dynamic relationships between individual and collective dimensions of POs' evidence-based activism. The argument is that such forms of activism participate in the co-construction of "gene worlds" (Timmermans & Shostak, 2015), through the relations between various actors and institutions: POs, scientific and medical professionals, public health institutions, and healthcare systems. [less ▲]

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See detailCHARACTERIZATION OF THE KABYLE BREED OF HEN (THAYAZIT LEKVAYEL) AND ITS FARMING SYSTEM IN THE REGION OF CHEMINI AND BOUZEGUENE (ALGERIA)
Moula, Nassim ULg

in INTERNATIONAL CONFERENCE Agriculture Development in the Context of International Integration: Opportunities and Challenges (2016, December 07)

The rural poultry in Algeria is a supplier of popular products. The aims of this study are to characterize local chickens in Kabylie in terms of the livestock practices, management, flock structures, uses ... [more ▼]

The rural poultry in Algeria is a supplier of popular products. The aims of this study are to characterize local chickens in Kabylie in terms of the livestock practices, management, flock structures, uses, performance and phenotypes. The present survey addresses this issue in the case of Kabylie, a mountainous coastal region of Algeria, and concerns 28 households raising poultry and a morpho - biometric description of 388 (290 females and 98 males) adult local chickens. The farming practices is characterized by a reduction in the time allocated for this activity and to deal with production costs which are aspects of an unproductive extensive livestock system considered as a secondary activity. The body weight is 2.03 ± 0.22 kg and 1.61 ± 0.19 kg respectively in the male and the female. The age at first egg, egg weight, egg production per hen per clutch, number of clutches per year, hatchability and number of chicks weaned are 28.00 ± 3.82 weeks, 49.03 ± 3.66 g, 13.57 ± 1.64, 3.82 ± 1.14, 89.29 ± 9.79% and 7.82 ±1.75 respectively. The comb type is mostly single (89.43%). Skin colours are principally white (39.18%) and yellow (39.43). The comb and wattles are mostly red (93.30). Shanks colours are principally yellow (49.74%) and white (24.23%). The most common plumage colours are salmon (14.43%), white (12.11%), black (17%), grey (9.54%) and gold (9.02%). The genetic improvement of local poultry breeds is also to consider, provided that the suitability of the animal with respect to the context of its breeding is preserved. [less ▲]

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See detailIntroduction du Dossier de traduction
Borotto, Jessica ULg; Cavazzini, Andrea

in Cahiers du GRM (2016), 10

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See detailBrisons le système, pouvoir aux femmes ! (Padoue, 1974)
Borotto, Jessica ULg

in Cahiers du GRM (2016), 10

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See detailDrawing technical contrasts to address prenatal testing
Thoreau, François ULg

Conference (2016, December 07)

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See detailDanse, rituel, philosophie (présentation et animation de discussion)
Caeymaex, Florence ULg

Conference given outside the academic context (2016)

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See detailGNSS: Principle, limitations and perspectives
Warnant, René ULg

Conference given outside the academic context (2016)

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See detailL'échec de Weimar et l'avènement du régime national-socialiste
Brüll, Christoph ULg

Conference given outside the academic context (2016)

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See detailRésister à l’essentialisation de l’Allemagne : Les Temps Modernes, revue franco-allemande ?
Franck, Thomas ULg

in Trajectoires (2016), 10

Im Zentrum des vorliegenden Aufsatzes steht die Doppelausgabe (46-47) der französischen Zeitschrift Temps Modernes, die unter dem Titel „Allemagne“ im August-September 1949 erschien und einen besonderen ... [more ▼]

Im Zentrum des vorliegenden Aufsatzes steht die Doppelausgabe (46-47) der französischen Zeitschrift Temps Modernes, die unter dem Titel „Allemagne“ im August-September 1949 erschien und einen besonderen Fall von kulturellem und intellektuellem Transfer zwischen Deutschland und Frankreich darstellt. Mit Mitteln der Diskursanalyse und der Imagologie sollen hier rhetorische Strategien herausgearbeitet werden, die der Realisierung eines kritischen Projekts und der Anprangerung der Stereotypen dienen, die Deutschland damals zugeschrieben wurden. Aufgestellt wird folgende These: Indem sie Intellektuelle aus unterschiedlichen Orten und Disziplinen und heterogenes Wissen zusammenbringt, bietet sich die Zeitschrift besonders gut für eine kritische Reflexion der herrschenden Ideologien und kollektiven Überzeugungen an. Indem es Deutschen mit kommunistischer und antifaschistischer Gesinnung das Wort erteilt, will das Heft „Allemagne“ zu Erkenntnissen über ein ‚anderes Deutschland‘ kommen, das von Aufstand und Widerstand geprägt ist, und bricht so mit einer Reduktion des Landes auf eine unveränderliche und monolithische Identität, die als gleichermaßen fügsam und autoritär verstanden wurde. [less ▲]

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See detailIn vitro evaluation of biocompatibility of uncoated thermally reduced graphene and carbon nanotube-loaded PVDF membranes with adult neural stem cell-derived neurons and glia
Defteralı, Çağla; Verdejo, Raquel; Majeed, Shahid et al

in Frontiers in Bioengineering and Biotechnology (2016), 4(n° 64),

Graphene, graphene-based nanomaterials (GBNs), and carbon nanotubes (CNTs) are being investigated as potential substrates for the growth of neural cells. However, in most in vitro studies, the cells were ... [more ▼]

Graphene, graphene-based nanomaterials (GBNs), and carbon nanotubes (CNTs) are being investigated as potential substrates for the growth of neural cells. However, in most in vitro studies, the cells were seeded on these materials coated with various proteins implying that the observed effects on the cells could not solely be attributed to the GBN and CNT properties. Here, we studied the biocompatibility of uncoated thermally reduced graphene (TRG) and poly(vinylidene fluoride) (PVDF) membranes loaded with multi-walled CNTs (MWCNTs) using neural stem cells isolated from the adult mouse olfactory bulb (termed aOBSCs). When aOBSCs were induced to differentiate on coverslips treated with TRG or control materials (polyethyleneimine-PEI and polyornithine plus fibronectin- PLO/F) in a serum-free medium, neurons, astrocytes, and oligodendrocytes were generated in all conditions, indicating that TRG permits the multi-lineage differentiation of aOBSCs. However, the total number of cells was reduced on both PEI and TRG. In a serum-containing medium, aOBSC-derived neurons and oligodendrocytes grown on TRG were more numerous than in controls; the neurons developed synaptic boutons and oligodendrocytes were more branched. In contrast, neurons growing on PVDF membranes had reduced neurite branching, and on MWCNTs-loaded membranes oligodendrocytes were lower in numbers than in controls. Overall, these findings indicate that uncoated TRG may be biocompatible with the generation, differentiation, and maturation of aOBSC-derived neurons and glial cells, implying a potential use for TRG to study functional neuronal networks. [less ▲]

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See detailWhy and how to repair concrete? Compatibility assessment
Courard, Luc ULg

Scientific conference (2016, December 06)

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See detailSocialisation et articulation des régimes d'historicités
Grandjean, Geoffrey ULg

Conference given outside the academic context (2016)

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See detailLa concurrence mémorielle et la lutte contre le racisme
Grandjean, Geoffrey ULg

Conference given outside the academic context (2016)

Detailed reference viewed: 15 (3 ULg)