Last 7 days
Bookmark and Share    
Full Text
Peer Reviewed
See detailA methodological evaluation of volumetric measurement techniques including three-dimensional imaging in breast surgery
HOEFFELIN, Harry; JACQUEMIN, Denise ULg; Defaweux, Valérie ULg et al

in BioMed Research International (2014), 2014

Breast surgery currently remains very subjective and each intervention depends on the ability and experience of the operator. To date, no objective measurement of this anatomical region can codify surgery ... [more ▼]

Breast surgery currently remains very subjective and each intervention depends on the ability and experience of the operator. To date, no objective measurement of this anatomical region can codify surgery. In this light, we wanted to compare and validate a new technique for 3D scanning (LifeViz 3D) and its clinical application. Materials and methods. - We tested the use of the 3D LifeViz system (Quantificare) to perform volumetric calculations in various settings ("in situ" in cadaveric dissection, of control prostheses and in clinical patients) and we compared this system to other techniques (CT scanning and Archimedes' principle) under the same conditions. Results. - We were able to identify the benefits (feasibility, safety, portability, low patient stress) and limitations (underestimation of the “in situ” volume, subjectivity of contouring, and patient selection) of the LifeViz 3D system, concluding that the results are comparable with other measurement techniques. Conclusion. - The prospects of this technology seem promising in numerous applications in clinical practice to limit the subjectivity of breast surgery. [less ▲]

Detailed reference viewed: 15 (2 ULg)
Full Text
See detailWhat roles for energy cooperatives in the diffusion of distributed generation technologies?
Bauwens, Thomas ULg

E-print/Working paper (2014)

Whereas a centralized model of electricity infrastructure is still dominant today, many scholars advocate the diffusion of distributed generation technologies, implying geographically dispersed and small ... [more ▼]

Whereas a centralized model of electricity infrastructure is still dominant today, many scholars advocate the diffusion of distributed generation technologies, implying geographically dispersed and small-scale generation units located close to consumers. However, there exist various barriers of different natures to a large-scale penetration of these technologies. In this article, we focus on the behavioral and psychological ones, emphasizing the roles that citizens have to play in this issue. More specifically, we explore a specific way of involving citizens in such diffusion, namely energy cooperatives. After presenting the driving forces of the emergence of cooperative firms in the energy sector, we examine the assets of the cooperative ownership structure from the perspectives of behavioral economics and social psychology. Our analysis enables us to build a model of how cooperatives may enhance consumer engagement in the diffusion of distributed generation technologies. This provides a basic theoretical framework for future empirical research. [less ▲]

Detailed reference viewed: 41 (5 ULg)
Full Text
See detailIntegrating the weight of history into the alignment framework: the case of distributed generation technologies
Bauwens, Thomas ULg

E-print/Working paper (2014)

Whereas a centralized energy supply system is still dominant today, the energy sector is currently witnessing the development of small-scale and more geographically dispersed generation units, so-called ... [more ▼]

Whereas a centralized energy supply system is still dominant today, the energy sector is currently witnessing the development of small-scale and more geographically dispersed generation units, so-called distributed generation technologies. So-called "alignment framework" proposes a very useful approach to look at this evolution. Yet, we argue in this paper that this framework does not fully take into account the inertia associated with past technological and institutional choices that may hinder future changes. Relying on the concept of socio-technical lock-in, we illustrate this point with the case of the diffusion of distributed generation technologies. Based on this analysis, we propose an adaptation of the alignment framework to integrate these elements. [less ▲]

Detailed reference viewed: 30 (4 ULg)
Full Text
Peer Reviewed
See detailL’impact de certains choix didactiques sur la performance en expression écrite et l’efficacité du feedback correctif
Noiroux, Kevin ULg; Simons, Germain ULg

in Babylonia (2014)

Many teachers use written corrective feedback, a teaching practice that consists in correcting the lexico-grammatical errors of the student’s written production. Due to its time-consuming nature for the ... [more ▼]

Many teachers use written corrective feedback, a teaching practice that consists in correcting the lexico-grammatical errors of the student’s written production. Due to its time-consuming nature for the teacher, it makes sense to strive to make corrective feedback as effective as possible. In this exploratory study, we collaborated with a high school teacher of Federation Wallonia-Brussels to create a didactic sequence that aimed at assessing the efficacy of corrective feedback in a fifth-year class. Students’ answers to a survey, as well as their written production performance, seem to point out that some pedagogical choices may have had a negative impact on the performance of corrective feedback. We underline (1) the lack of lexico-grammatical training exercises, (2) the absence of testing on lexico-grammatical knowledge, (3) the lack of work on ideas that can be transferred to the final production, (4) the lack of work on the text type and (5) the limits of formative assessment. The underlying assumption is that students’ written production performance, hence the efficacy of corrective feedback, can be improved through those didactic choices. [less ▲]

Detailed reference viewed: 20 (3 ULg)
Full Text
See detailCouvin/Couvin : Trou de l'Abîme
Miller, Rebecca ULg; Cattelain, Pierre; Otte, Marcel ULg et al

in Chronique de l'Archéologie Wallonne (2014), 21

Detailed reference viewed: 10 (2 ULg)
Full Text
Peer Reviewed
See detailMMP-Mediated Collagen Remodeling and Vessel Functions
Noël, Agnès ULg; Sounni, Nor Eddine ULg

in BRIX, K.; STOCKER, W. (Eds.) Proteases: Structure and Function, (2014)

Detailed reference viewed: 15 (1 ULg)
Full Text
Peer Reviewed
See detailUpper airway imaging in sleep-disordered breathing.
POIRRIER, Anne-Lise ULg; Fanielle, Julien; Bruwier, Annick ULg et al

in Acta neurologica Belgica (2014)

Our understanding of sleep-disordered breathing has evolved considerably over the past three decades, and clinical techniques of evaluation have progressed tremendously. Myriad imaging techniques are now ... [more ▼]

Our understanding of sleep-disordered breathing has evolved considerably over the past three decades, and clinical techniques of evaluation have progressed tremendously. Myriad imaging techniques are now available for the physician to approach the dynamic features resulting in turbulent airflow, upper airway narrowing or collapse at different levels. Controversy exists in the choice of investigations, probably because the best evaluation should be a combination of different techniques. Physical, radiographic, endoscopic and acoustic evaluations could be integrated to understand the degree and the levels of airway reduction and/or obstruction in a given patient. This review focuses on cost-effective and easily implemented techniques in daily practice, allowing quality assessment of the dynamic anatomy of sleep-disordered breathing: cephalometry, (sleep-)endoscopy and acoustic reflectometry of the upper airway. [less ▲]

Detailed reference viewed: 19 (7 ULg)
Full Text
Peer Reviewed
See detailV. Van Saaze, Installation Art and the Museum : Presentation and Conservation of Changing Artworks
D'Haenens, Manon ULg

in CeROArt : Conservation, Exposition, Restauration d'Objets d'Art (2014), (9),

Detailed reference viewed: 12 (3 ULg)
Full Text
Peer Reviewed
See detailA volatile sex pheromone in the invasive ladybeetle Harmonia axyridis (Pallas) (Coleoptera: Coccinellidae)
Fassotte, Bérénice ULg; Fischer, Christophe ULg; Durieux, Delphine ULg et al

in Communications in Agricultural and Applied Biological Sciences (2014), 79(1), 79-81

Detailed reference viewed: 22 (9 ULg)
Full Text
Peer Reviewed
See detailSHIP2 signaling in normal and pathological situations: Its impact on cell proliferation.
Elong Edimo, W; Schurmans, Stéphane ULg; Roger, PP et al

in Advances in Biological Regulation (2014), 54

Phosphoinositide 5-phosphatases are critical enzymes in modulating the concentrations of PI(3,4,5)P3, PI(4,5)P2 and PI(3,5)P2. The SH2 domain containing inositol 5-phosphatases SHIP1 and SHIP2 belong to ... [more ▼]

Phosphoinositide 5-phosphatases are critical enzymes in modulating the concentrations of PI(3,4,5)P3, PI(4,5)P2 and PI(3,5)P2. The SH2 domain containing inositol 5-phosphatases SHIP1 and SHIP2 belong to this family of enzymes that dephosphorylate the 5 position of PI(3,4,5)P3 to produce PI(3,4)P2. Data obtained in zebrafish and in mice have shown that SHIP2 is critical in development and growth. Exome sequencing identifies mutations in the coding region of SHIP2 as a cause of opsismodysplasia, a severe but rare chondrodysplasia in human. SHIP2 has been reported to have both protumorigenic and tumor suppressor function in human cancer very much depending on the cell model. This could be linked to the relative importance of PI(3,4)P2 (a product of SHIP2 phosphatase activity) which is also controlled by the PI 4-phosphatase and tumor suppressor INPP4B. In the glioblastoma cell line 1321 N1, that do not express PTEN, lowering SHIP2 expression has an impact on the levels of PI(3,4,5)P3, cell morphology and cell proliferation. It positively stimulates cell proliferation by decreasing the expression of key regulatory proteins of the cell cycle such as p27. Together the data point out to a role of SHIP2 in development in normal cells and at least in cell proliferation in some cancer derived cells. [less ▲]

Detailed reference viewed: 22 (8 ULg)
Full Text
Peer Reviewed
See detailInositol trisphosphate 3-kinase B is increased in human Alzheimer brain and exacerbates mouse Alzheimer pathology
Stygelbout, V.; Leroy, K.; Pouillon, V. et al

in Brain : A Journal of Neurology (2014), 137

S. Schurmans and J.-P. Brion contributed equally to this work Corresponding author: S. Schurmans, Laboratoire de Génétique Fonctionnelle, GIGA-Research Centre, Building 34, Université de Liège, rue de ... [more ▼]

S. Schurmans and J.-P. Brion contributed equally to this work Corresponding author: S. Schurmans, Laboratoire de Génétique Fonctionnelle, GIGA-Research Centre, Building 34, Université de Liège, rue de l’Hôpital 1, 4000-Liège, Belgium. Abstract: Inositol (1,4,5) trisphosphate 3-kinase B phosphorylates inositol 1,4,5-trisphosphate into inositol 1,3,4,5-tetrakisphosphate and controls signal transduction in various hematopoietic cells. Surprisingly, it has been reported that Inositol (1,4,5) trisphosphate 3-kinase B mRNA level is significantly increased in the cerebral cortex of Alzheimer patients, compared to control subjects. Since Extracellular signal-regulated kinases 1/2 activation is increased in Alzheimer brain and since Inositol (1,4,5) trisphosphate 3-kinase B is a regulator of Extracellular signal-regulated kinases 1/2 activation in some hematopoietic cells, we tested whether this increased activation in Alzheimer’s disease might be related to an increased activity of Inositol (1,4,5) trisphosphate 3-kinase B. We show here that Inositol (1,4,5) trisphosphate 3-kinase B protein level was 3 fold increased in the cerebral cortex of most Alzheimer patients, compared to control subjects, and accumulated in dystrophic neurites associated to amyloid plaques. In mouse Neuro-2a neuroblastoma cells, Inositol (1,4,5) trisphosphate 3-kinase B overexpression was associated with increased cell apoptosis and increased β-secretase 1 activity leading to amyloid-β peptides overproduction. In this cellular model, an inhibitor of Mitogen-activated kinase kinases 1/2 completely prevented amyloid-β peptides overproduction. Transgenic overexpression of Inositol (1,4,5) trisphosphate 3-kinase B in mouse forebrain neurons was not sufficient to induce amyloid plaques formation or TAU hyperphosphorylation. However, in the 5X Familial Alzheimer’s Disease mouse model, neuronal Inositol (1,4,5) trisphosphate 3-kinase B overexpression significantly increased Extracellular signal-regulated kinases 1/2 activation and β-secretase 1 activity, resulting in exacerbated Alzheimer pathology as shown by increased astrogliosis, amyloid-β40 peptide production and TAU hyperphosphorylation. No impact on pathology was observed in the 5X Familial Alzheimer’s Disease mouse model when a catalytically inactive Inositol (1,4,5) trisphosphate 3-kinase B protein was overexpressed. Together, our results point to the Inositol (1,4,5) trisphosphate 3-kinase B /Inositol 1,3,4,5-tetrakisphosphate/Extracellular signal-regulated kinases 1/2 signaling pathway as an important regulator of neuronal cell apoptosis, Amyloid precursor protein processing and TAU phosphorylation in Alzheimer’s disease, and suggest that Inositol (1,4,5) trisphosphate 3-kinase B could represent a new target for reducing pathology in human AD patients with increased cortical Inositol (1,4,5) trisphosphate 3-kinase B expression. [less ▲]

Detailed reference viewed: 20 (9 ULg)
Full Text
Peer Reviewed
See detailDESIGN, MODELING AND EXPERIMANTATION OF A REVERSIBLE HP-ORC PROTOTYPE
Dumont, Olivier ULg; Quoilin, Sylvain ULg; Lemort, Vincent ULg

in Proceedings of the ASME TURBO EXPO 2014 (2014)

This paper presents an innovative system comprising a heat pump connected to a solar roof and a geothermal heat exchanger. This heat pump is also able to invert its cycle and operate as an ORC. By using ... [more ▼]

This paper presents an innovative system comprising a heat pump connected to a solar roof and a geothermal heat exchanger. This heat pump is also able to invert its cycle and operate as an ORC. By using the whole rooftop (hereunder called “absorber”) as a heat source, a large amount of heat is generated throughout the year. This heat is used in priority to cover the building annual heating needs and the surplus heat generated during the summer is utilized to generate electricity in a so-called HP/ORC module. This paper will thus focus on these two main points: designing of the prototype and results from experimentation. This paper demonstrates the feasibility of such a prototype with encouraging performance in ORC and HP modes. Experimentally, a COP of 4.2 is reached in heat pump mode and a global efficiency of 5.6 is obtained in ORC mode. Possible means of improvement and perspectives are finally described. [less ▲]

Detailed reference viewed: 12 (0 ULg)
Full Text
Peer Reviewed
See detailDesign, modelling, performance optimization and experimentation of a reversible HP/ORC prototype.
Dumont, Olivier ULg; Quoilin, Sylvain ULg; Lemort, Vincent ULg

in Proceeding of the 11th International Energy Agency Heat Pump Conference. (2014)

This paper presents an innovative system comprising a water/water heat pump connected to a solar roof and a geothermal heat exchanger. This unit is able to invert its cycle and operate as an Organic ... [more ▼]

This paper presents an innovative system comprising a water/water heat pump connected to a solar roof and a geothermal heat exchanger. This unit is able to invert its cycle and operate as an Organic Rankine Cycle. The solar roof is producing a large amount of heat throughout the year. This allows covering the building annual heating needs and furthermore, electricity is produced thanks to the surplus of heat in a so-called HP/ORC reversible unit. This paper is focusing on these three main points: modeling, design and experimentation of the prototype. This paper demonstrates the feasibility of such a prototype with encouraging performance in ORC and HP modes. First simulations of the HP/ORC system, with components optimally sized, indicate that, in ORC mode, for the weather conditions of Copenhagen, the electrical energy produced over one year reaches 4030 kWh and the nominal efficiency of the cycle is 7.6%. The nominal COP of the heat pump is 4.2 (condenser exhaust temperature of 60°C and evaporator supply temperature of 15°C). Experimentally, a COP of 4.21 (condensation temperature of 61°C and evaporation temperature of 21°C). is achieved in heat pump mode and a global ORC efficiency of 5.7% is obtained in ORC mode (condenser exhaust temperature of 25°C and evaporator supply temperature of 88°C). [less ▲]

Detailed reference viewed: 24 (1 ULg)
Full Text
Peer Reviewed
See detailUncertainty assessment of ephemeral gully identification, characteristics and topographic threshold when using aerial photographs in agricultural settings
Maugnard, Alexandre; Cordonnier, Hélène; Degré, Aurore ULg et al

in EARTH SURFACE PROCESSES AND LANDFORMS (2014)

Manual digitizing on aerial photographs is still commonly used for characterizing gully erosion over large areas. Even when automated detection procedures are implemented, manual digitizing is frequently ... [more ▼]

Manual digitizing on aerial photographs is still commonly used for characterizing gully erosion over large areas. Even when automated detection procedures are implemented, manual digitizing is frequently being resorted to in order to constitute reference datasets used for training and validation. In both cases, manual digitizing entails some subjective decisions on behalf of the operator, which introduces uncertainty into the resulting datasets. To assess the magnitude of this uncertainty, 11 experienced operators were asked to digitize and classify ephemeral gullies (EGs) on cropland following a standardized methodology. The resulting 11 datasets were compared in terms of number, type and location of EGs. Furthermore, for EGs located on a welldefined runoff flow concentration axis, the slope versus contributing area topographic thresholds required for initiating gully channels were assessed using four thresholding methods, and compared across the 11 datasets. The operators identified 259 different EGs. However, the number (52–139) and sum total length (8.9–23.7 km) of EGs varied widely across operators. Only 34% of the EGs were digitized by more than half of the operators, and 7% were identified by all. Identification of EGs located on a well-defined flow concentration axis proved least subjective. The longer the EG and the more fields the EG crossed, the larger the number of operators that were able to identify it. EGs were also most easily identified when located in sugar beet fields as compared to other crops. EG classification and topographic threshold lines were also found to be strongly operator-dependent. Quantile regression appeared to be one of the most robust thresholding methods. Operator subjectivity when digitizing EGs on orthophotographs introduces uncertainty that should be taken into account in future remote sensing-based studies of EG erosion whenever they rely, in part or in full, on manual photograph interpretation. [less ▲]

Detailed reference viewed: 10 (2 ULg)
Full Text
Peer Reviewed
See detailDIMENSIONNEMENT ET EXPÉRIMENTATION D’UNE UNITÉ POMPE À CHALEUR / ORC RÉVERSIBLE
Dumont, Olivier ULg; Quoilin, Sylvain ULg; Lemort, Vincent ULg

in Procceding du septième édition du colloque francophone en énergie, environnement, économie et thermodynamique 2014 (2014)

L’union européenne doit réduire les émissions de gaz à effet de serre de 80% par rapport au niveau des années 90 d’ici 2020. Les ménages représentent 27% de la consommation finale. Dans ce cadre, les ... [more ▼]

L’union européenne doit réduire les émissions de gaz à effet de serre de 80% par rapport au niveau des années 90 d’ici 2020. Les ménages représentent 27% de la consommation finale. Dans ce cadre, les bâtiments dont la consommation d’énergie est quasi nulle (NZEB – Nearly Zero Energy Building) sont d’une importance considérable. A partir de 2019, tous les nouveaux bâtiments devront présenter une production d’énergie renouvelable supérieure à la consommation d’énergie primaire. C’est dans ce cadre que le concept de PAC/ORC prend tout son sens. Ce système innovant comprend une pompe à chaleur eau/eau (PAC) reliée à un toit solaire et à un échangeur de chaleur géothermique. Cette pompe à chaleur est également capable d'inverser son cycle et de fonctionner comme un Cycle Organique de Rankine (ORC). En utilisant le toit solaire comme source de chaleur, une grande quantité de chaleur est générée tout au long de l'année. Cette chaleur est utilisée en priorité pour couvrir les besoins de chauffage annuels et le surplus de chaleur généré au cours de l'été est utilisée pour produire de l'électricité dans l’unité PAC / ORC. L’article s’articule en 4 parties. Tout d’abord, l’introduction présente les trois modes de fonctionnement. Ensuite, les modèles des composants et l’évaluation des performances au point nominal de conception sont décrits. Par après, le dimensionnement et le choix des composants sont réalisés sur bases de simulations annuelles avec un pas de temps d’une heure. Enfin, les premiers résultats expérimentaux sont présentés. Un rendement de 5,7% est atteint en mode ORC (avec une température de condensation de 25°C et une température d’évaporation de 88°C) alors qu’un COP de 4,2 est obtenu en mode pompe à chaleur (avec une température de condensation de 61°C et une température d’évaporation de 21°C). [less ▲]

Detailed reference viewed: 13 (2 ULg)
Full Text
Peer Reviewed
See detailQUELLE EST LA PLACE DE L’HUMAIN AU SEIN DES RECOMMANDATIONS, DES CONCERTATIONS ONCOLOGIQUES
BARTHELEMY, Nicole ULg; BOGA, Deniz ULg; PRINCEN, Fabienne ULg et al

in Revue Médicale de Liège (2014), 69(Supp 1), 9-12

Le patient atteint de cancer bénéficie à l’heure actuelle d’une médecine très technique, de plus en plus ciblée et individualisée. Et l’Homme dans tout cela ? Divers outils ont été développés afin d’aider ... [more ▼]

Le patient atteint de cancer bénéficie à l’heure actuelle d’une médecine très technique, de plus en plus ciblée et individualisée. Et l’Homme dans tout cela ? Divers outils ont été développés afin d’aider les médecins et l’ensemble des soignants à concilier la médecine contemporaine et les droits fondamentaux du patient. Parmi ceux-ci, on trouve les Concertations Oncologiques Multidisciplinaires (COM) ainsi que les recommandations de traitement publiées par les socié - tés scientifiques nationales ou internationales. La prise en charge des patients doit être interdisciplinaire et basée sur une médecine factuelle. Ce processus de prise de décisions parta - gée doit, au final, être en accord avec les souhaits du patient. Cette approche doit lui permettre de conserver son autonomie et d’être l’acteur principal dans les prises de décision. [less ▲]

Detailed reference viewed: 7 (2 ULg)
Full Text
Peer Reviewed
See detailA new criterion to assess distributional homogeneity in hyperspectral images of solid pharmaceutical dosage forms
Sacre, Pierre-Yves ULg; Lebrun, Pierre ULg; Chavez, Pierre-François ULg et al

in Analytica Chimica Acta (2014), 818

During galenic formulation development, homogeneity of distribution is a critical parameter to check since it may influence activity and safety of the drug. Raman hyperspectral imaging is a technique of ... [more ▼]

During galenic formulation development, homogeneity of distribution is a critical parameter to check since it may influence activity and safety of the drug. Raman hyperspectral imaging is a technique of choice for assessing the distributional homogeneity of compounds of interest. Indeed, the combination of both spectroscopic and spatial information provides a detailed knowledge of chemical composition and component distribution. Actually, most authors assess homogeneity using parameters of the histogram of intensities (e.g. mean, skewness and kurtosis). However, this approach does not take into account spatial information and loses the main advantage of imaging. To overcome this limitation, we propose a new criterion: Distributional Homogeneity Index (DHI). DHI has been tested on simulated maps and formulation development samples. The distribution maps of the samples were obtained without validated calibration model since different formulations were under investigation. The results obtained showed a linear relationship between content uniformity values and DHI values of distribution maps. Therefore, DHI methodology appears to be a suitable tool for the analysis of homogeneity of distribution maps even without calibration during formulation development. [less ▲]

Detailed reference viewed: 18 (12 ULg)
Full Text
Peer Reviewed
See detailStrategies for Using the Sheep Ovarian Cortex as a Model in Reproductive Medicine
Fransolet, Maïté ULg; Labied, Soraya ULg; HENRY, Laurie ULg et al

in PLoS ONE (2014), 9(3), 91073

Objective: To evaluate and compare the distribution and density of primordial follicles within a whole sheep ovary and to gain insight into how to overcome the impact of natural follicular heterogeneity ... [more ▼]

Objective: To evaluate and compare the distribution and density of primordial follicles within a whole sheep ovary and to gain insight into how to overcome the impact of natural follicular heterogeneity on the experimental results. Design: Histological study. Setting: Academic research center. Animals: Five- to nine-month-old ewes. Interventions: Freshly sampled whole sheep ovaries were collected and prepared for histological analysis. Main Outcome Measure(s): The follicular densities and distributions were determined for hematoxylin and eosin sections. A mathematical model was derived based on the follicle counts and Monte-Carlo simulations. Results: Heterogeneous distributions and densities of primordial follicles were identified 1) for distinct areas of the same ovarian cortex, 2) between the ovaries of the same animal and 3) across different ewes. A mathematical model based on the analysis of 37,153 primordial follicles from 8 different ovaries facilitated the estimation of the number of cortical biopsies and sections that had to be analyzed to overcome such heterogeneity. Conclusion: The influence of physiological follicular heterogeneity on experimental and clinical results can be overcome when a definite number of cortical pieces and sections are taken into consideration. [less ▲]

Detailed reference viewed: 3 (0 ULg)
Full Text
Peer Reviewed
See detailUTILISATION DE L’IMAGERIE FONCTIONNELLE EN RADIOTHÉRAPIE
LALLEMAND, François ULg; LAKOSI, Ferenc ULg; HUSTINX, Roland ULg et al

in Revue Médicale de Liège (2014), 69(Supp 1), 20-28

Les progrès technologiques réalisés par l’image- rie médicale l’ont placée au centre de la prise en charge des patients oncologiques, tant au niveau du diagnostic, du pro - nostic et du suivi que dans la ... [more ▼]

Les progrès technologiques réalisés par l’image- rie médicale l’ont placée au centre de la prise en charge des patients oncologiques, tant au niveau du diagnostic, du pro - nostic et du suivi que dans la prise en charge thérapeutique. En effet, l’imagerie représente, à l’heure actuelle, la pierre angulaire des traitements de radiothérapie. Les objectifs du radiothérapeute sont d’irradier le plus précisément possible la tumeur à dose curative, tout en évitant les organes sains. Pour y arriver, le radiothérapeute utilise de façon routinière l’imagerie anatomique (Scanner et IRM). Depuis quelques années, le développement des différentes imageries métabo - liques et fonctionnelles, comme l’imagerie par émission de positons (PET-CT) et la résonnance magnétique fonctionnelle, ouvrent de nouvelles possibilités thérapeutiques grâce aux informations qu’elles apportent sur la biologie des tumeurs. Cet article décrit, de manière non exhaustive, les différentes imageries anatomiques et métaboliques à la disposition du radiothérapeute. [less ▲]

Detailed reference viewed: 7 (1 ULg)