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See detailThree-Dimensional Morphology of the Left Ventricular Outflow Tract: Impact on Grading Aortic Stenosis Severity.
Caballero, Luis; Saura, Daniel; Oliva-Sandoval, Maria Jose et al

in Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography (2017), 30(1), 28-35

BACKGROUND: Left ventricular outflow tract (LVOT) measurement is a critical step in the quantification of aortic valve area. The assumption of a circular morphology of the LVOT may induce some errors. The ... [more ▼]

BACKGROUND: Left ventricular outflow tract (LVOT) measurement is a critical step in the quantification of aortic valve area. The assumption of a circular morphology of the LVOT may induce some errors. The aim of this study was to assess the three-dimensional (3D) morphology of the LVOT and its impact on grading aortic stenosis severity. METHODS: Fifty-eight patients with aortic stenosis were studied retrospectively. LVOT dimensions were measured using 3D transesophageal echocardiography at three levels: at the hinge points (HP) of the aortic valve and at 4 and 8 mm proximal to the annular plane. Results were compared with standard two-dimensional echocardiographic measurements. RESULTS: Three-dimensional transesophageal echocardiography showed a funnel shape that was more circular at the HP and more elliptical at 4 and 8 mm proximal to the annular plane (circularity index = 0.92 vs 0.83 vs 0.76, P < .001). Cross-sectional area was smaller at the HP and larger at 4 and 8 mm from the annular plane (3.6 vs 3.9 vs 4.1 cm2, P = .001). The best correlation between two-dimensional and 3D transesophageal echocardiographic dimensions was at the HP (intraclass correlation coefficient = 0.75; 95% CI, 0.59-0.86). When the HP approach was selected, there was a reduction in the percentage of patients with low flow (from 41% to 29%). CONCLUSIONS: A large portion of patients with aortic stenosis have funnel-shaped and elliptical LVOTs, a morphology that is more pronounced in the region farther from the annular plane. Two-dimensional LVOT measurement closer to the annular plane has the best correlation with 3D measurements. Measurement of the LVOT closer to the annular plane should be encouraged to reduce measurement errors. [less ▲]

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See detailCardiopulmonary exercise testing is a better outcome predictor than exercise echocardiography in asymptomatic aortic stenosis.
Domanski, Olivia; Richardson, Marjorie; Coisne, Augustin et al

in International Journal of Cardiology (2017), 227

BACKGROUND: Objective assessment of maximal aerobic capacity using peak oxygen consumption (peak VO2) can be helpful in the management of patients with asymptomatic aortic stenosis (AS). The relationship ... [more ▼]

BACKGROUND: Objective assessment of maximal aerobic capacity using peak oxygen consumption (peak VO2) can be helpful in the management of patients with asymptomatic aortic stenosis (AS). The relationship between peak VO2 and AS severity criteria derived from rest and supine exercise echocardiography (SEE) has never been explored. OBJECTIVES: We aimed to determine whether low peak VO2 (<85% of predicted value) is associated with severity parameters in SEE, and poor clinical outcome. METHODS: Fifty one asymptomatic patients (mean age of 54+/-21years) with moderate to severe aortic stenosis (Vmax>3m/s) and left ventricle ejection fraction>50% prospectively underwent resting and SEE and cardiopulmonary exercise testing (CPX). RESULTS: Peak VO2 was lower than expected (21.9+/-7.4mL/kg/min), i.e. <85% of predicted value in 57% patients, secondary to cardiac limitation in most of them (69%). In multiple regression analysis, age, BMI and female gender were the only independent determinants of peak VO2. Interestingly no parameter derived from SEE was associated with peak VO2. After 21+/-7month follow-up, no patient died, 20 underwent cardiac surgery. Peak VO2<85% of predicted value was associated with lower event free survival compared to normal peak VO2 (57%+/-11% vs 93+/-6%, p=0.036) whereas no exercise echocardiographic parameter could predict such events. Peak VO2>/=85% had a negative predictive value of 97%. CONCLUSION: CPX detects a high proportion of false asymptomatic AS patients with poorer outcome that cannot be predicted by SEE markers of AS severity. Assessment of aerobic capacity should be part of current approach within a "watchful waiting" strategy. [less ▲]

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See detailHéra, Apollon et l'Héraion de Délos à la période archaïque
Pirenne-Delforge, Vinciane ULg

in Mazarakis Ainian, Alexandre (Ed.) Les sanctuaires archaïques des Cyclades (2017)

L’Héraion de Délos fut identifié en 1911, quand les archéologues de l’École française d’Athènes mirent au jour un dépôt archaïque dans un édifice surmonté du temple dorique toujours visible au flanc du ... [more ▼]

L’Héraion de Délos fut identifié en 1911, quand les archéologues de l’École française d’Athènes mirent au jour un dépôt archaïque dans un édifice surmonté du temple dorique toujours visible au flanc du mont Cynthe. Des inscriptions archaïques sur les objets dédiés attestèrent qu’Héra était la déesse honorée en ce lieu. Les interprétations de son culte dans l’île ont alors oscillé entre deux pôles : c’était soit une manière pour les Déliens d’apaiser sa colère contre Léto qui avait donné naissance à Apollon, ainsi que le raconte l’Hymne homérique au dieu, soit une tentative de maintenir sur l’île des fidèles tentés d’aller honorer la déesse dans le grand sanctuaire de Samos. Ces deux points de vue sont infondés : le premier, parce que les traditions narratives ont leur propre langage qui ne peut être projeté comme tel sur les cultes ; le second, parce que le désir d’honorer Héra à Délos peut être expliqué en soi, sans faire référence à une prétendue compétition avec le fameux sanctuaire de la déesse samienne. Afin de fonder l’analyse du dossier sur des prémisses plus valides, trois questions sont ici posées. 1) Qui furent les fidèles de la déesse pendant la période archaïque, des femmes, des hommes, des Délien(ne)s, des étrangers ? 2) Quelle place l’Héraion occupait-il parmi les autres sanctuaires déliens et quel était le rôle d’Héra parmi les autres dieux de Délos ? 3) Pouvons-nous utiliser l’Hymne homérique à Apollon pour comprendre le culte d’Héra et la situation de son temple sur l’île ? Ces trois questions sont abordées l’une après l’autre : la première par une analyse des types d’offrandes faites à Héra et de l’identité des dédicants qui ont inscrit leur démarche ; la deuxième en prenant en considération l’ensemble du panthéon délien archaïque ; la troisième en évaluant attentivement ce qu’implique, sur un plan narratif, la colère d’Héra contre Léto. [less ▲]

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See detailEditor's Choice - Management of Descending Thoracic Aorta Diseases: Clinical Practice Guidelines of the European Society for Vascular Surgery (ESVS).
Riambau, V.; Bockler, D.; Brunkwall, J. et al

in European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery (2017), 53(1), 4-52

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See detailLe juge doit-il être frappé d'anathème? Examen de la responsabilité civile pour la faute du juge en droits québécois et belge
Bouhon, Frédéric ULg; Lacroix, Mariève

in Les dynamiques de modernisation de la justice dans les pays du nord et du sud (2017)

L'article présenté dans le cadre du colloque de Casablanca est un résumé des travaux de droit comparé menés à propos de la question de la responsabilité civile pour la faute des juges dans l'exercice de ... [more ▼]

L'article présenté dans le cadre du colloque de Casablanca est un résumé des travaux de droit comparé menés à propos de la question de la responsabilité civile pour la faute des juges dans l'exercice de leur fonction, au Québec et en Belgique. [less ▲]

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See detail3D electrical resistivity tomography of karstified formations using cross-line measurements
Van Hoorde, Maurits; Hermans, Thomas ULg; Dumont, Gaël ULg et al

in Engineering Geology (2017), 220

The acquisition of a full 3D survey on a large area of investigation is difficult, and from a practitioner’s point of view, very costly. In high-resolution 3D surveys, the number of electrodes increases ... [more ▼]

The acquisition of a full 3D survey on a large area of investigation is difficult, and from a practitioner’s point of view, very costly. In high-resolution 3D surveys, the number of electrodes increases rapidly and the total number of electrode combinations becomes very large. In this paper, we propose an innovative 3D acquisition procedure based on the roll-along technique. It makes use of 2D parallel lines with additional cross-line measurements. However, in order to increase the number of directions represented in the data, we propose to use cross-line measurements in several directions. Those cross-line measurements are based on dipole-dipole configurations as commonly used in cross-borehole surveys. We illustrate the method by investigating the subsurface geometry in a karstic environment for a future wind turbine project. We first test our methodology with a numerical benchmark using a synthetic model. Then, we validate it through a field case application to image the 3D geometry of karst features and the top of unaltered bedrock in limestone formations. We analyze the importance of cross-line measuring and analyze their capability for accurate subsurface imaging. The comparison with standard parallel 2D surveys clearly highlighted the added value of the cross-lines measurements to detect those structures. It provides crucial insight in subsurface geometry for the positioning of the future wind turbine foundation. The developed method can provide a useful tool in the design of 3D ERT survey to optimize the amount of information collected within a limited time frame. [less ▲]

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See detailTransnational Health Insurances as Social Remittances: The Case of Congolese Immigrants in Belgium
Lafleur, Jean-Michel ULg; Lizin, Olivier

in Magdalena, Nowicka; Vojin, Šerbedžija (Eds.) Migration and Social Remittances in a Global Europe (2017)

For many years, the migration and development literature has looked at the impact of financial remittances on immigrant relatives’ access to health care. More recent work on social remittances also ... [more ▼]

For many years, the migration and development literature has looked at the impact of financial remittances on immigrant relatives’ access to health care. More recent work on social remittances also examined the circulation of ideas and practices through migration and its impact on behavior and consumption patterns in the home country. Surprisingly, however, migration scholars have neglected the interactions between remittances and local health systems in countries of origin. This is all the more surprising considering the abundant literature on health and development that has documented numerous non-governmental initiatives to improve access to care in the Global South in recent years. Among those initiatives, community-based health insurances (CBHI) have attracted significant attention. CBHI are voluntary risk-pooling schemes run by not-for-profit organizations; they collect fees among users at the local level and organize access to care with providers. While the growing literature on CBHI is shedding light on the potential of civil society organizations to replace or compensate for weak public health systems, it forgets that —in many parts of the world— access to the necessary capital to join those schemes is still very dependent on emigration of some family members. In other words, for many families worldwide, strategies to access health care have become transnational. In this chapter we look at a specific form of CHBI that we call ‘transnational health insurance’ (THI). These insurance schemes are set up by immigrants in cooperation with a multitude of actors including, on the one hand, health insurance companies and development aid agencies in destination countries and, on the other hand, health care providers in countries of origin. THIs offer health coverage to a selected number of non-migrant relatives in the home country based on a premium paid directly by immigrants to the insurance company in their country of residence. Analyzing the creation and implementation of one THI in the Belgian-Congolese postcolonial context allow us in the last part the paper to discuss the concept of hybridity in the study of remittances as well as identify the drivers of immigrant transnational engagement in the area of health. [less ▲]

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See detailQuand la métrique grecque offre un problème stimulant à la programmation informatique
Purnelle, Gérald ULg

in Faure, Richard; Zucker, Arnaud; Mellet, Sylvie (Eds.) Poétique de la syntaxe. Rythmique de la langue. Hommages à Michèle Biraud (2017)

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See detailMolecular Tools for the Detection and Quantification of Toxigenic Cyanobacteria
Kurmayer, Rainer; Sivonen, Kaarina; Wilmotte, Annick ULg et al

Book published by Wiley (2017)

A guide to state-of-the-art molecular tools for monitoring and managing the toxigenicity of cyanobacteria Runaway climate change has made the monitoring and management of toxigenic organisms in the ... [more ▼]

A guide to state-of-the-art molecular tools for monitoring and managing the toxigenicity of cyanobacteria Runaway climate change has made the monitoring and management of toxigenic organisms in the world’s bodies of water more urgent than ever. In order to influence public policy regarding the detection and quantification of those organisms, it is incumbent upon scientists to clearly demonstrate to policy makers the increase of toxigenic cyanobacteria and the threats they pose. As molecular methods can handle many samples in short time, they are the most reliable, cost-effective tools currently available for tracking cyanotoxicity worldwide. This volume arms scientists with the tools they need to track toxigenicity in surface waters and food supplies and, hopefully, to develop new techniques for managing the spread of toxic cyanobacteria. This book offers the first comprehensive treatment of molecular tools for monitoring cyanotoxicity. Growing out of the findings of the landmark European Cooperation in Science and Technology Cyanobacteria project (CYANOCOST), it provides detailed, practical coverage of the full array of available molecular tools and protocols, from water sampling, nucleic acid extraction, and downstream analysis—including PCR and qPCR based methods—to genotyping (DGGE), diagnostic microarrays, and community characterization using next-gen sequencing techniques. [less ▲]

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See detailScale-dependent diffusion anisotropy in nanoporous silicon
Kondrashova, D; Lauerer, A; Mehlhorn, D et al

in Scientific Reports (2017), 7

Nanoporous silicon produced by electrochemical etching of highly B-doped p-type silicon wafers can be prepared with tubular pores imbedded in a silicon matrix. Such materials have found many technological ... [more ▼]

Nanoporous silicon produced by electrochemical etching of highly B-doped p-type silicon wafers can be prepared with tubular pores imbedded in a silicon matrix. Such materials have found many technological applications and provide a useful model system for studying phase transitions under con nement. This paper reports a joint experimental and simulation study of di usion in such materials, covering displacements from molecular dimensions up to tens of micrometers with carefully selected probe molecules. In addition to mass transfer through the channels, di usion (at much smaller rates) is also found to occur in directions perpendicular to the channels, thus providing clear evidence of connectivity. With increasing displacements, propagation in both axial and transversal directions is progressively retarded, suggesting a scale-dependent, hierarchical distribution of transport resistances (“constrictions” in the channels) and of shortcuts (connecting “bridges”) between adjacent channels. The experimental evidence from these studies is con rmed by molecular dynamics (MD) simulation in the range of atomistic displacements and rationalized with a simple model of statistically distributed “constrictions” and “bridges” for displacements in the micrometer range via dynamic Monte Carlo (DMC) simulation. Both ranges are demonstrated to be mutually transferrable by DMC simulations based on the pore space topology determined by electron tomography. [less ▲]

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See detailGuidelines for the Detection of Babesia and Theileria Parasites.
Lempereur, Laetitia ULg; Beck, Relja; Fonseca, Isabel et al

in Vector borne and zoonotic diseases (Larchmont, N.Y.) (2017), 17(1), 51-65

The genera Babesia and Theileria (phylum Apicomplexa, order Piroplasmida) are mainly transmitted by Ixodid ticks in which the sexual part of their life cycle followed by sporogony takes place. They ... [more ▼]

The genera Babesia and Theileria (phylum Apicomplexa, order Piroplasmida) are mainly transmitted by Ixodid ticks in which the sexual part of their life cycle followed by sporogony takes place. They include protozoan parasites that infect erythrocytes of a variety of vertebrate hosts, including domestic and wild animals, with some Babesia spp. also infecting humans. Babesia sporozoites transmitted in the tick's saliva during the bloodmeal directly infect erythrocytes, where they asexually multiply to produce pear-shaped merozoites in the process of merogony; whereas a pre-erythrocytic schizogonic life stage in leukocytes is found in Theileria and precedes merogony in the erythrocytes. The wide spectrum of Babesia and Theileria species and their dissimilar characteristics with relation to disease severity, transmission, epidemiology, and drug susceptibility stress the importance of accurate detection of babesiosis and theileriosis and their causative agents. These guidelines review the main methods currently used for the detection of Babesia and Theileria spp. for diagnostic purposes as well as epidemiological studies involving their vertebrate hosts and arthropod vectors. Serological methods were not included once they did not indicate current infection but rather exposure. [less ▲]

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See detailRange size heritability and diversification patterns in the liverwort genus Radula
Patiño, J.; Wang, J.; Renner, M.A.M. et al

in Molecular Phylogenetics & Evolution (2017), 106

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See detailFifth European Dirofilaria and Angiostrongylus Days (FiEDAD) 2016
Simón, F.; Kartashev, V.; González-Miguel, J. et al

in Parasites & Vectors (2017), 10(1), 5

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See detailEmission and oxidation of methane in a meromictic, eutrophic and temperate lake (Dendre, Belgium)
Roland, Fleur ULg; Darchambeau, François ULg; Morana, Cédric ULg et al

in Chemosphere (2017)

We sampled the water column of the Dendre stone pit lake (Belgium) in spring, summer, autumn and winter. Depth profiles of several physico-chemical variables, nutrients, dissolved gases (CO2, CH4, N2O ... [more ▼]

We sampled the water column of the Dendre stone pit lake (Belgium) in spring, summer, autumn and winter. Depth profiles of several physico-chemical variables, nutrients, dissolved gases (CO2, CH4, N2O), sulfate, sulfide, iron and manganese concentrations and d13C-CH4 were determined. We performed incubation experiments to quantify CH4 oxidation rates, with a focus on anaerobic CH4 oxidation (AOM), without and with an inhibitor of sulfate reduction (molybdate). The evolution of nitrate and sulfate concentrations during the incubations was monitored. The water column was anoxic below 20 m throughout the year, and was thermally stratified in summer and autumn. High partial pressure of CO2 and CH4 and high concentrations of ammonium and phosphate were observed in anoxic waters. Important nitrous oxide and nitrate concentration maxima were also observed (up to 440 nmol L- 1 and 80 mmol L -1, respectively). Vertical profiles of d13C-CH4 unambiguously showed the occurrence of AOM. Important AOM rates (up to 14 mmol L -1 d- 1) were observed and often co-occurred with nitrate consumption peaks, suggesting the occurrence of AOM coupled with nitrate reduction. AOM coupled with sulfate reduction also occurred, since AOM rates tended to be lower when molybdate was added. CH4 oxidation was mostly aerobic (~80% of total oxidation) in spring and winter, and almost exclusively anaerobic in summer and autumn. Despite important CH4 oxidation rates, the estimated CH4 fluxes from the water surface to the atmosphere were high (mean of 732 mmol m- 2 d- 1 in spring, summer and autumn, and up to 12,482 mmol m- 2 d- 1 in winter). [less ▲]

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See detailThermal Conductivity of Straw Bales: Full Size Measurements Considering the Direction of the Heat Flow
Costes, Jean-Philippe; Evrard, Arnaud; Biot, Benjamin et al

in Buildings (2017), 7(11), 1-15

The thermal conductivity of straw bales is an intensively discussed topic in the international straw bale community. Straw bales are, by nature, highly heterogeneous and porous. They can have a relatively ... [more ▼]

The thermal conductivity of straw bales is an intensively discussed topic in the international straw bale community. Straw bales are, by nature, highly heterogeneous and porous. They can have a relatively large range of density and the baling process can influence the way the fibres are organised within the bale. In addition, straw bales have a larger thickness than most of the insulating materials that can be found in the building industry. Measurement apparatus is usually not designed for such thicknesses, and most of the thermal conductivity values that can be found in the literature are defined based on samples in which the straw bales are resized. During this operation, the orientation of the fibres and the density may not be preserved. This paper starts with a literature review of straw bale thermal conductivity measurements and presents a measuring campaign performed with a specific Guarded Hot Plate, designed to measure samples up to 50 cm thick. The influence of the density is discussed thoroughly. Representative values are proposed for a large range of straw bales to support straw-bale development in the building industry. [less ▲]

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See detailLibération conditionnelle
Bastard, Joséphine ULg

in Les mots de la Justice - Recht Spraak (2017)

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See detailRéinsertion
Bastard, Joséphine ULg

in Les mots de la Justice - Recht Spraak (2017)

L'ouvrage propose un regard sur les expériences de la Justice belge, dans une perspective de vulgarisation. La "réinsertion" désigne l’idée du retour à la société de ceux qui en ont été exclus par ... [more ▼]

L'ouvrage propose un regard sur les expériences de la Justice belge, dans une perspective de vulgarisation. La "réinsertion" désigne l’idée du retour à la société de ceux qui en ont été exclus par l’incarcération. Définir la réinsertion est pourtant complexe car la notion recouvre différentes dimensions. [less ▲]

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See detailDroit matériel européen - plan de cours 2017
Van Cleynenbreugel, Pieter ULg

Learning material (2017)

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See detailLe droit à des élections libres et Internet
Bouhon, Frédéric ULg

in Van Enis, Quentin; De Terwangne, Cécile (Eds.) L'Europe des droits de l'homme à l'heure d'Internet (2017)

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