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See detailIs the Sørensen test valid to assess muscle fatigue of the trunk extensor muscles?
Demoulin, Christophe ULg; Boyer, Mathieu; Duchateau, Jacques et al

in Journal of Back and Musculoskeletal Rehabilitation (2015), 00

BACKGROUND: Very few studies have quantified the degree of fatigue characterized by the decline in the maximal voluntary contraction (MVC) force of the trunk extensors induced by the widely used Sørensen ... [more ▼]

BACKGROUND: Very few studies have quantified the degree of fatigue characterized by the decline in the maximal voluntary contraction (MVC) force of the trunk extensors induced by the widely used Sørensen test. OBJECTIVE: Measure the degree of fatigue of the trunk extensor muscles induced by the Sørensen test. METHODS: Eighty young healthy subjects were randomly divided into a control group (CG) and an experimental group (EG), each including 50% of the two genders. The EG performed an isometric MVC of the trunk extensors (pre-fatigue test) followed by the Sørensen test, the latter being immediately followed by another MVC (post-fatigue test). The CG performed only the preand post-fatigue tests without any exertion in between. RESULTS: The comparison of the pre- and post-fatigue tests revealed a significant (P <0.05) decrease in MVC force normalized by body mass (−13%) in the EG, whereas a small increase occurred in the CG (+2.7%, P = 0.001). CONCLUSIONS: This study shows that the Sørensen test performed until failure in a young healthy population results in a reduced ability of the trunk extensor muscles to generate maximal force, and indicates that this test is valid for the assessment of fatigue in trunk extensor muscles. [less ▲]

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See detailA note on the equivalence between observed and expected information functions with polytomous IRT models
Magis, David ULg

in Journal of Educational & Behavioral Statistics (2015), 40

The purpose of this note is to study the equivalence of observed and expected (Fisher) information functions with polytomous item response theory (IRT) models. It is established that observed and expected ... [more ▼]

The purpose of this note is to study the equivalence of observed and expected (Fisher) information functions with polytomous item response theory (IRT) models. It is established that observed and expected information functions are equivalent for the class of divide-by-total models (including partial credit, generalized partial credit, rating scale and nominal response models), but not for the class of difference models (including the graded response and modified graded response models). Yet, observed information function remains positive in both classes. Straightforward connections with dichotomous IRT models and further implications are outlined. [less ▲]

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See detailObjectivité et subjectivité dans la critique husserlienne du relativisme
Seron, Denis ULg

in Gyemant, Maria (Ed.) Psychologie et psychologisme (2015)

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See detailSartre in Venedig: der Mann, der in die Kälte ging
Cormann, Grégory ULg; Viehöver, Vera ULg

in Bulletin d'Analyse Phénoménologique (2015), 11

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See detail"Passer la ligne" : La rencontre de Fanon et de Sartre
Cormann, Grégory ULg

in Luneau, Marie-Pier; Saint-Amand, Denis (Eds.) La Préface. Formes, enjeux et effets d’un discours d’escorte (2015)

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See detailLectures de La Reine Albemarle ou le dernier touriste. Ontologie, autobiographie, politique
Cormann, Grégory ULg

in Bulletin d'Analyse Phénoménologique (2015), 11(1),

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See detailAgeism and its clinical impact in oncogeriatry: state of knowledge and therapeutic leads
Schroyen, Sarah ULg; Adam, Stéphane ULg; JERUSALEM, Guy ULg et al

in Clinical Interventions in Aging (2015), 10

Cancer is a major health problem that is widespread in elderly people. Paradoxically, older people suffering from cancer are often excluded from clinical trials and are undertreated when compared to ... [more ▼]

Cancer is a major health problem that is widespread in elderly people. Paradoxically, older people suffering from cancer are often excluded from clinical trials and are undertreated when compared to younger patients. One explanation for these observations is age stigma (ie, stereotypes linked to age, and thus ageism). These stigmas can result in deleterious consequences for elderly people’s mental and physical health in “normal” aging. What, then, is the impact in a pathological context, such as oncology? Moreover, health care professionals’ attitudes can be tainted with ageism, thus leading to undesirable consequences for patients. To counter these stigmas, we can apply some possible interventions emerging from research on normal aging and from social psychology, such as intergenerational contact, activation of positive stereotypes, self-affirmation, and so on; these tools can improve opinions of aging among the elderly people themselves, as well as health care professionals, thus affecting patients’ mental and physical health. [less ▲]

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See detailMutations in the voltage-gated potassium channel gene KCNH1 cause Temple-Baraitser syndrome and epilepsy.
Simons, Cas; Rash, Lachlan D.; Crawford, Joanna et al

in Nature genetics (2015), 47(1), 73-7

Temple-Baraitser syndrome (TBS) is a multisystem developmental disorder characterized by intellectual disability, epilepsy, and hypoplasia or aplasia of the nails of the thumb and great toe. Here we ... [more ▼]

Temple-Baraitser syndrome (TBS) is a multisystem developmental disorder characterized by intellectual disability, epilepsy, and hypoplasia or aplasia of the nails of the thumb and great toe. Here we report damaging de novo mutations in KCNH1 (encoding a protein called ether a go-go, EAG1 or KV10.1), a voltage-gated potassium channel that is predominantly expressed in the central nervous system (CNS), in six individuals with TBS. Characterization of the mutant channels in both Xenopus laevis oocytes and human HEK293T cells showed a decreased threshold of activation and delayed deactivation, demonstrating that TBS-associated KCNH1 mutations lead to deleterious gain of function. Consistent with this result, we find that two mothers of children with TBS, who have epilepsy but are otherwise healthy, are low-level (10% and 27%) mosaic carriers of pathogenic KCNH1 mutations. Consistent with recent reports, this finding demonstrates that the etiology of many unresolved CNS disorders, including epilepsies, might be explained by pathogenic mosaic mutations. [less ▲]

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See detailLes supports pour l'étude fournis à l'élève en sciences biologiques sont-ils créateurs d'inégalités? Etude exploratoire de productions de futurs enseignants en Fédération Wallonie-Bruxelles (Belgique)
Poffé, Corentin ULg; Laschet, Mélanie ULg; Hindryckx, Marie-Noëlle ULg

in Spirale : Revue de Recherches en Education (2015), 55

Une revue de la littérature permet d’attribuer à de nombreux facteurs les inégalités dans l’apprentissage. Parmi ceux-ci, nous avons choisi d’analyser, avec le regard du formateur d’enseignants, les ... [more ▼]

Une revue de la littérature permet d’attribuer à de nombreux facteurs les inégalités dans l’apprentissage. Parmi ceux-ci, nous avons choisi d’analyser, avec le regard du formateur d’enseignants, les supports pour l’étude proposés par nos étudiants futurs enseignants aux élèves du secondaire (15 à 18 ans) en vue de l’évaluation, lors des cours de sciences biologiques. Cette « photographie instantanée » des supports pour l’étude nous a fourni un état des lieux qui nous permet d’objectiver nos impressions de formateurs quant au rôle des supports pour l’étude dans la problématique des inégalités scolaires. [less ▲]

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See detailLes nouveaux outils de diagnostic et de pronostic de la myopathie atypique
Habyarimana, Jean ULg; BOEMER, François ULg; Amory, Hélène ULg et al

in Proceeding de la 41ème Journée de la Recherche équine (2015)

In equines, ingestion of hypoglycin A, a toxin produced in the seeds (samaras) of sycamore maple (Acer pseudoplatanus) tree alters the energetic metabolism of muscle cells and results in atypical myopathy ... [more ▼]

In equines, ingestion of hypoglycin A, a toxin produced in the seeds (samaras) of sycamore maple (Acer pseudoplatanus) tree alters the energetic metabolism of muscle cells and results in atypical myopathy (AM). This alterations leads to a characteristic biochemical profile of acylcarnitines (AC) that enables to confirm the diagnosis of AM. This study aims at validating a methodology for the dosage of hypoglycin A in vegetal extracts but also in blood. In addition, the biochemical profile in AC has been determined in AM cases (5 survivors and 13 deceased) and in 5 horses suffering from exercise-induced myopathy. The AC profiles of these horses have been compared to the one of healthy horses (n = 35). This study showed that hypoglycin A was present in seeds and spring seedlings of sycamore and also in blood of AM cases horses. In addition, the establishment of AC profile contributes to the diagnostic and helps to assess the prognosis of AM cases. [less ▲]

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See detailEstetrol is a weak estrogen antagonizing estradiol-dependent mammary gland proliferation.
Gérard, Céline ULg; Blacher, Silvia ULg; Communal, Laudine et al

in Journal of Endocrinology (2015), 224(1), 86-95

Estetrol (E4) is a natural estrogen produced exclusively by the human fetal liver during pregnancy. Its physiological activity remains unknown. In contrast to ethinyl estradiol (EE) and estradiol (E2), E4 ... [more ▼]

Estetrol (E4) is a natural estrogen produced exclusively by the human fetal liver during pregnancy. Its physiological activity remains unknown. In contrast to ethinyl estradiol (EE) and estradiol (E2), E4 has a minimal impact on liver cells activity and could provide a better safety profile in contraception or hormone therapy. The aim of this study was to delineate if E4 exhibits an activity profile distinct from that of E2 on mammary gland. Compared to E2, E4 acted as a low affinity estrogen in both, human in vitro and murine in vivo, models. E4 was 100 times less potent than E2 to stimulate the proliferation of human breast epithelial (HBE) cells and murine mammary gland in vitro and in vivo, respectively. This effect was prevented by fulvestrant and by tamoxifen supporting the notion that ERalpha is the main mediator of the estrogenic effect of E4 on the breast. Interestingly, when E4 was administered along with E2, it significantly antagonized the strong stimulatory effect of E2 on HBE cells proliferation and on the growth of mammary ducts. This study characterizes for the first time the impact of E4 on mammary gland. Our results highlight that E4 is less potent than E2 and exhibits antagonistic properties towards the proliferative effect of E2 on breast epithelial cells. These data support E4 as a potential new estrogen for clinical use with a reduced impact on breast proliferation. [less ▲]

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See detailDoes reward unpredictability reflect risk?
Anselme, Patrick ULg

in Behavioural Brain Research (2015), 280(1), 119-127

Most decisions made in real-life situations are risky because they are associated with possible negative consequences. Current models of decision-making postulate that the occasional, unpredictable ... [more ▼]

Most decisions made in real-life situations are risky because they are associated with possible negative consequences. Current models of decision-making postulate that the occasional, unpredictable absence of reward that may result from free choice is a negative consequence interpreted as risk by organisms in laboratory situations. I argue that such a view is difficult to justify because, in most experimental paradigms, reward omission does not represent a cost for the decision maker. Risk only exists when unpredictability may cause a potential loss of own limited resources, whether energetic, social, financial, and so on. Thus the experimental methodologies used to test humans and non-humans relative to risk-taking seem to be limited to studying the effects of reward uncertainty in the absence of true decision cost. This may have important implications for the conclusions that can be drawn with respect to the neurobehavioural determinants of risk-taking in real-life situations. [less ▲]

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See detailFe–Ti–V–P ore deposits associated with Proterozoic massif-type anorthosites and related rocks
Charlier, Bernard ULg; Namur, Olivier; Bolle, Olivier ULg et al

in Earth-Science Reviews (2015), 141(0), 56-81

Magmatic rocks containing economic concentrations of iron, titanium, vanadium and phosphorous are commonly associated with massif-type anorthosites and related rocks. This rock association is part of the ... [more ▼]

Magmatic rocks containing economic concentrations of iron, titanium, vanadium and phosphorous are commonly associated with massif-type anorthosites and related rocks. This rock association is part of the anorthosite–mangerite–charnockite–(rapakivi-)granite suites that are restricted to the Proterozoic. Understanding the geochemistry and emplacement mechanisms of ilmenite, magnetite and apatite ore deposits is crucial for exploration, efficient mining operations and ore processing. This review discusses the controlling factors on the grade of an ore, its mineralogy, and its major and trace element distribution. We present petrogenetic models of currently mined deposits (Lac Tio, Tellnes, Damiao) and discuss the characteristics of minor ore bodies from anorthosite provinces worldwide (Grenville, North China Craton, East European Craton, Rogaland, Laramie). Models of formation of anorthosite and related rocks are presented, as well as the nature of the possible parental magmas of the suite. A mineralogical classification of Fe–Ti ores is proposed: (1) Gabbro-noritic ilmenite ore ± apatite ± magnetite; (2) Ti-magnetite-dominated ore; (3) Nelsonite (Fe–Ti oxides + apatite); and (4) Rutile-ilmenite ore. The stability of ilmenite and magnetite is then critically reviewed and the influence of various factors, particularly oxygen fugacity and crystallization pressure, is examined. We discuss liquidus compositions of Fe–Ti oxides and the behavior of important trace elements such as Cr and V, both of which are sensitive to fO2 variations. Post-cumulus evolution of both oxides can occur due to re-equilibration with trapped liquid, re-equilibration with ferromagnesian silicates, exsolution, oxidation, reaction between ilmenite and magnetite, and metamorphic overprinting. These various processes are described and their effects on the oxide geochemistry are emphasized. Several potential ore-forming processes have been invoked and can explain the formation of huge concentration of ilmenite, ± magnetite, ± apatite. Fractional crystallization can be combined with crystal sorting and plagioclase buoyancy to produce relative enrichment of dense ore minerals. Silicate liquid immiscibility can segregate conjugate Si-rich and Fe-rich melts, the latter being enriched in Fe–Ti–P. Magma mixing can produce hybrid magmas located in a single-phase field of the phase diagram and precipitate a pure ilmenite cumulate. Alternative processes are also described, such as ejection of Fe–Ti-enriched residual melts by filter-pressing and compaction, solid-state remobilization of ilmenite in veins, and hydrothermal transport of Fe and Ti from the host anorthosite followed by concentration in veins and lenticular ore bodies. The magnetic properties of Fe–Ti ore deposits present contrasting signatures, depending on whether the natural remanent magnetization is dominated by hemo-ilmenite or multi-domain magnetite. Micro- and macro-scale deformation features of ore rocks are intimately correlated with magma emplacement, and with ballooning of the anorthosite diapir associated with gravitational sagging of dense ore bodies. Exploration perspectives show that oxide-apatite gabbronorites are interesting targets because ilmenite in these rocks is poorer in Cr and Mg, and because the Ti-resource may be combined with apatite and vanadiferous magnetite. [less ▲]

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See detailA branch-and-price algorithm for 2-period vehicle routing problems
Crama, Yves ULg; Rezaei Sadrabadi, Mahmood ULg; Van Woensel, Tom

E-print/Working paper (2015)

We consider a Vehicle Routing Problem (VRP) with deterministic orders in two periods from a set of stores. Orders in period 1 (2) can be postponed (advanced) to the other period but any diversion from the ... [more ▼]

We consider a Vehicle Routing Problem (VRP) with deterministic orders in two periods from a set of stores. Orders in period 1 (2) can be postponed (advanced) to the other period but any diversion from the initial orders incurs a penalty. From the perspective of a Logistics Service Provider (LSP), such diversions could be beneficial if savings in the routing costs outweigh the penalties. So could they be from a store's view, as the store can set a high enough penalty to compensate the diversion from its own optimal orders. In this paper, we introduce a new model where we seek a better solution for the LSP, compared to solving two independent VRPs with fixed orders, by allowing orders to be fully postponed or advanced. We apply a branch-and-price algorithm to solve this model to optimality. Many cutting-edge techniques are implemented to have an efficient branch-and-price algorithm, and two ideas to possibly improve the upper bound are tested. We draw algorithmic and managerial insights based on our test instances. [less ▲]

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See detailCompte-rendu de l'ouvrage de M. Le Blanc et P. Trudeau: La réadaptation de l'adolescent antisocial
Mathys, Cécile ULg

in Canadian Journal of Criminology & Criminal Justice = Revue Canadienne de Criminologie et de Justice Pénale (2015), 57(1),

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See detailPostcolonial Thesholds: Gateways and Borders
Wilson, Janet; Tunca, Daria ULg

in Journal of Postcolonial Writing (2015), 51(1), 1-107

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See detailDes chiffres de la politique à la politique du chiffre Le cas des réformes du financement de la recherche dans les universités belge francophones.
Fallon, Catherine ULg

in Reflets et Perspectives de la Vie Economique (2015)

“Governing by numbers” is a trend on the increase in public action. Numbers tend to pervade the politico-administrative space without questioning neither the quantification processes which produce them ... [more ▼]

“Governing by numbers” is a trend on the increase in public action. Numbers tend to pervade the politico-administrative space without questioning neither the quantification processes which produce them nor the conditions of their utilization in government. And yet the use of numbers and data in political arguments contribute to transform the terms of the debate: politics can transform data and indicators, but one should not neglect how numbers affect policymaking. This article proposes as case study the analysis of some recent transformations of public research funding mechanism in universities in French speaking Belgium. It questions the systemic effects of the use of performance indicators in public management in this sector and it proposes some starting points for a discussion of their impact on the quality of the political debate. [less ▲]

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See detailComplete analytical procedure to assess the response of a frame submitted to a column loss
Huvelle, Clara; Hoang, Van Long ULg; Jaspart, Jean-Pierre ULg et al

in Engineering Structures (2015), 86

The present paper gives a global overview on recent developments performed at the University of Liege on structural robustness of buildings for the specific scenario ‘‘loss of a column’’. In particular, a ... [more ▼]

The present paper gives a global overview on recent developments performed at the University of Liege on structural robustness of buildings for the specific scenario ‘‘loss of a column’’. In particular, a complete analytical method to assess the response of a 2D frame losing statically one of its columns is presented in details. This method is based on the development of alternative load paths in the damaged structure and takes into account the couplings between the different parts of the structure which are differently affected by the column loss. Also, the validation of the developed method through comparison to experimental and numerical evidences is presented. [less ▲]

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See detailEffects of isoflurane and sevoflurane on the neutrophilmyeloperoxidase system of horses
MINGUET, Grégory ULg; Franck, Thierry ULg; JORIS, Jean ULg et al

in Veterinary Immunology and Immunopathology (2015)

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See detailIntroduction - Postcolonial Thresholds: Gateways and Borders
Wilson, Janet; Tunca, Daria ULg

in Journal of Postcolonial Writing (2015), 51(1), 1-6

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