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Et si j'avais une boule de cristal... je prédirais le devenir d'un mycosis fongoïde.Franchimont, Claudine ; HERMANNS, Trinh ; PIERARD, Gérald ![]() in Dermatologie Actualité (2013), 134 Detailed reference viewed: 12 (1 ULg) Characterization of spontaneous collagen fibrillogenesis in a cell-free and tension-free environment.PIERARD, Gérald ; Hermanns-Lê, Trinh ; Delvenne, Philippe et alin Clinical & Experimental Dermatology (2013) The collagen fibril packing that forms threads and bundles is poorly defined, despite the fact that it is important for distinct aspects of the adventitial and reticular dermis. The present study explored ... [more ▼] The collagen fibril packing that forms threads and bundles is poorly defined, despite the fact that it is important for distinct aspects of the adventitial and reticular dermis. The present study explored an in vitro fibrillogenesis model using the property of heat polymerization. The process was performed on glass slides with mixtures of collagen I and III, and the material was viewed by scanning electron microscopy. In all instances, collagen I and III formed fibrils with regular sizes. The formation of threads was influenced by the relative proportions of collagen I and III; increasing the relative proportion of collagen I resulted in the formation of threads showing increasing variations in thickness. These findings are in line with the differential presentation and compositions of the different parts of the dermis. The possible interventions of stromal cells and of other macromoleules of the extracellular matrix were not considered in this study. [less ▲] Detailed reference viewed: 9 (1 ULg) CARACTERISATION ET AMELIORATION DE LA QUALITE DE LA BIERE TRADITIONNELLE RWANDAISE « IKIGAGE » FABRIQUEE A BASE DE SORGHOLyumugabe Loshima, François ![]() Doctoral thesis (2013) Ikigage is a Rwandese traditional beer made from sorghum malt and local plants, mainly Vernonia amygdalina “umubirizi”. However, this beer remains less attractive than Western beers of pils type because ... [more ▼] Ikigage is a Rwandese traditional beer made from sorghum malt and local plants, mainly Vernonia amygdalina “umubirizi”. However, this beer remains less attractive than Western beers of pils type because of poor hygienic quality, variations of organoleptic quality and limited shelf life. The aim of this work is to characterize ikigage beer in order to improve its hygienic quality and to reduce the organoleptic variations using the local raw materials. The first part of our study shows that ikigage beer marketed in Rwanda is characterized by the presence of Stapylococcus aureus and many micro-organisms of fecal origin (Escherichia coli and fecal streptococci), by the low ethanol content, high total acidity and an important amounts of proteins. The yeasts (Saccharomyces cerevisiae and Issatckenkia orientalis), followed by the lactic acid bacteria (Lactobacillus fermentum and Lactobacillus buchneri), are the predominant microorganisms involved in fermentation of ikigage beer fermentation. Besides, one of the major problems in sorghum beer brewing is the efficient conversion of the starch extracts into fermentable sugars due to the weak activity of β-amylase in sorghum malt. The use of Eleusine coracana “uburo” (Musama variety) malt (30%), associated with mashing decantation procedure, increases the content of sugar fermentable, maltose particularly, in sorghum wort, and consequently ethanol content in the beer. The second part of our study shows that V. amygdalina, known for its antibacterial properties and its bitterness similar to hops, contributes to the production of methyl salycilate, beta-damascenone and many terpenes compounds (δ-3-carene, β-farnesene, farnesol, β-citronellol and linalool), in the sorghum beer “ikigage”. This work reveals also the presence of 14 polyfunctional thiols in beers brewed with ‘non-Western’ raw materials. Among them, the well-known hop constituent 3-methyl-2-buten-1-thiol emerged as a key flavour in the unhopped beers containing V. amygdalina. V. amygdalina also contributes to the production of 1-butanethiol and 4-sulfanyl-4-methyl-2-pentanone in sorghum beer. However, contrary to hops, V. amygdalina addition during boiling also appears to strongly inhibit the production of 2-sulfanylethyl acetate. The third part of our study shows that the use of S. cerevisiae in combination with I. orientalis and L. fermentum as starter allows producing ikigage beer having the GRAS (generally recognized as safe) statute while preserving the organoleptic characteristics similar to those of local traditional beer “ikigage” produced by peasants. [less ▲] Detailed reference viewed: 20 (3 ULg) Fibromyalgie: un syndrome d'Ehlers-Danlos de type hypermobile qui s'ignore?; PIERARD, Gérald ; in Revue Médicale de Liège (2013), 68(1), 22-4 Some patients suffering from fibromyalgia present with clinical signs and alterations in the histopathology, immunohistochemistry and ultrastructure of the dermis similar to the Ehlers-Danlos syndrome ... [more ▼] Some patients suffering from fibromyalgia present with clinical signs and alterations in the histopathology, immunohistochemistry and ultrastructure of the dermis similar to the Ehlers-Danlos syndrome, hypermobile type (EDSH). Some types of fibromyalgia possibly represent an undiagnosed EDSH. [less ▲] Detailed reference viewed: 42 (2 ULg) MATHEMATICAL MODELING OF ENDOCHONDRAL OSSIFICATION THROUGH MUTUAL INHIBITION AND BISTABILITYGermain, Morgan ; Kerkhofs, Johan ; Geris, Liesbet ![]() Conference (2013) Detailed reference viewed: 16 (3 ULg) Critical assessment of diabetic xerosis.PIERARD, Gérald ; Franchimont, Claudine ; Scheen, André ![]() in Expert Opinion on Medical Diagnostics (2013), 7(2), 201-7 Introduction: Diabetes mellitus is commonly responsible for skin changes including discrete to mild xerosis. Areas covered: This review focuses on some selected relevant bioinstrumental methods assessing ... [more ▼] Introduction: Diabetes mellitus is commonly responsible for skin changes including discrete to mild xerosis. Areas covered: This review focuses on some selected relevant bioinstrumental methods assessing diabetes xerosis. Peer-reviewed articles on objective non-invasive methods were scrutinized. The reviewed methods address i) the xerosis severity grading scale, ii) corneodynamics referring to the desquamation rate, iii) electrometric assessment of skin hydration including skin capacitance mapping and iv) implication of the imperceptible perspiration. The subjective clinical assessment often fails to disclose diabetic xerosis with confidence and precision. By contrast, a multipronged biometrological approach identifies a cluster of diabetic patients who experience alterations in the structural and functional maturation of the stratum corneum. Expert opinion: A multipronged biometrological approach helps identifying the changes in the stratum corneum of diabetic xerosis. There is a continuum between the 'dry skin' feeling, xerosis and ichthyosiform presentations, particularly on the shins and feet of diabetic patients. [less ▲] Detailed reference viewed: 12 (2 ULg) Contingency ranking with respect to overloads in very large power systems taking into account uncertainty, preventive, and corrective actions; ; et al in IEEE Transactions on Power Systems (2013) This paper deals with day-ahead security management with respect to a postulated set of contingencies, while taking into account uncertainties about the next day generation/load scenario. In order to help ... [more ▼] This paper deals with day-ahead security management with respect to a postulated set of contingencies, while taking into account uncertainties about the next day generation/load scenario. In order to help the system operator in decision making under uncertainty, we aim at ranking these contingencies into four clusters according to the type of control actions needed to cover the worst uncertainty pattern of each contingency with respect to branch overload. To this end we use a fixed point algorithm that loops over two main modules: a discrete bi-level program (BLV) that computes the worst-case scenario, and a special kind of security constrained optimal power flow (SCOPF) which computes optimal preventive/corrective actions to cover the worst-case. We rely on a DC grid model, as the large number of binary variables, the large size of the problem, and the stringent computational requirements preclude the use of existing mixed integer nonlinear programming (MINLP) solvers. Consequently we solve the SCOPF using a mixed integer linear programming (MILP) solver while the BLV is decomposed into a series of MILPs. We provide numerical results with our approach on a very large European system model with 9241 buses and 5126 contingencies. [less ▲] Detailed reference viewed: 15 (2 ULg) The role of memory traces quality in directed forgetting: A comparison of young and elderly participants using the item procedureLorant, Caroline ; ; Bastin, Christine et alPoster (2013) Detailed reference viewed: 1 (1 ULg) Les Initiatives populaires de solidarité internationale en Wallonie et à Bruxelles : une autre manière de coopérer avec le Sud ?Godin, Julie ![]() in Wintgens, Sophie; Grandjean, Geoffrey (Eds.) Acteurs émergents. Perspectives pour la gouvernance mondiale (2013) Dans le contexte actuel d’harmonisation de l’aide au développement en vue du renforcement de son efficacité, leitmotiv de l’injonction à la professionnalisation du secteur, cette contribution s’attache à ... [more ▼] Dans le contexte actuel d’harmonisation de l’aide au développement en vue du renforcement de son efficacité, leitmotiv de l’injonction à la professionnalisation du secteur, cette contribution s’attache à questionner les spécificités des Initiatives Populaires de Solidarité Internationale (IPSI) en régions wallonne et bruxelloise au regard des ONG de Développement (ONGD) agréées par la Direction Générale de la coopération au Développement (DGD). Les IPSI sont des associations dont l’objet social principal est la solidarité internationale mais qui ne sont pas subsidiées de manière récurrente par les pouvoirs publics et fonctionnent donc majoritairement sur fonds propres. Elles résultent de l’engagement bénévole de leurs membres, ceux-ci exerçant ces activités solidaires en-dehors ou en sus de leurs occupations professionnelles officielles. Face aux ONGD, sous-champ professionnel qui se définit comme tel et dont les modalités d’accès sont contrôlées par la DGD, les projets menés par les IPSI questionnent les stratégies de développement actuelles des acteurs non gouvernementaux et la place de ces différents acteurs dans le champ des relations Nord-Sud. Ainsi, après avoir défini la professionnalisation dans le cadre de la coopération belge au développement, nous dresserons des pistes quant au regard que les ONGD portent sur les IPSI et inversement, sur les éléments mis en avant par ces dernières pour justifier leurs pratiques dans le champ de la solidarité internationale. [less ▲] Detailed reference viewed: 5 (2 ULg) Transboundary hydraulic modelling of extreme floods in the Meuse RiverDewals, Benjamin ; Erpicum, Sébastien ; Pirotton, Michel et alin The Wise Find Pleasure in Water (2013) Detailed inundation modelling was conducted along a 100 km long transnational section of the Meuse River (in Belgium and The Netherlands), using very similar models for the whole computation (2D unsteady ... [more ▼] Detailed inundation modelling was conducted along a 100 km long transnational section of the Meuse River (in Belgium and The Netherlands), using very similar models for the whole computation (2D unsteady models). As a result, damping of the flood waves could be quantified and the possible relevance of using a steady-state approach could be assessed. The new detailed 2D hydraulic simulations have demonstrated that only a very limited damping of the flood waves occurs along the simulated reaches. From the perspective of the variation in peak discharge, the study concludes that running the hydraulic model in steady mode makes perfectly sense. Nonetheless, the steady computations lead to extensive overestimations of the inundated extent and of the stored volume in the floodplains. The 2D unsteady model constitutes also a tool of primary interest, which is readily available to design and evaluate protection measures for flood-prone areas such as in the city of Liege. [less ▲] Detailed reference viewed: 14 (2 ULg) IDENTIFICATION AND DETERMINATION OF ALKALOIDS IN FUMARIA SPECIES FROM ROMANIA; ; Wauters, Jean-Noël et alin Digest Journal of Nanomaterials and Biostructures (2013), 8(2), 817-824 Detailed reference viewed: 1 (0 ULg) An intervention study on physical activity and cognitive functioning in people with Parkinson’s diseaseRouillard, Maud ; ; et alPoster (2013) Detailed reference viewed: 1 (1 ULg) The neural correlates of recollection and familiarity during aging; Bastin, Christine ; Genon, Sarah et alPoster (2013) Detailed reference viewed: 12 (2 ULg) The neural correlates of recollection and familiarity during aging; Bastin, Christine ; Genon, Sarah et alin Journal of Psychophysiology (2013), 27(Suppl 1), 48 Detailed reference viewed: 18 (2 ULg) Chronic exercise differentially impacts perceptual or motor inhibition as a function of age: a cross-sectional study; ; Collette, Fabienne et alPoster (2013) Detailed reference viewed: 1 (1 ULg) The role of memory traces quality in directed forgetting: A comparison of young and elderly participants using the item procedureCollette, Fabienne ; Lorant, Caroline ; et alConference (2013) Detailed reference viewed: 3 (2 ULg) Le rôle de la qualité de la trace mnésique en oubli dirigé: une comparaison de participants jeunes et âgés lors de la procédure itemCollette, Fabienne ; Lorant, Caroline ; et alConference (2013) Detailed reference viewed: 1 (1 ULg) Impacts of future floods and low flows on the economy in the Meuse basin; ; et al in Dewals, Benjamin; Fournier, Maïté (Eds.) Transboundary Water Management in a Changing Climate (2013) Climate change in Western Europe is projected to result in more humid winters and drier summers. Further, the sverities of floods and low flows are assumed to increase in the future. The impacts of these ... [more ▼] Climate change in Western Europe is projected to result in more humid winters and drier summers. Further, the sverities of floods and low flows are assumed to increase in the future. The impacts of these events could lead to adverse consequences on the economy. Given this framework, within the AMICE project, the impacts of future floods and low flow will be analyzed. A flood risk analysis in the Meuse basin is conducted taking into account future climate scenarios. Further, the impacts of future droughts and low flows are analyzed for the economic sectors energy production, agriculture and navigation. [less ▲] Detailed reference viewed: 6 (3 ULg) Hemodynamic comparison of restrictive mitral valve annuloplasty and mitral valve replacement for ischemic mitral regurgitation; ; et al in Circulation (2013) Detailed reference viewed: 11 (3 ULg) |
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