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See detailCompte-rendu de l'ouvrage de D. Chancé & A. Ricard : Traductions postcoloniales
Oumarou Mal Mazou, Rachid ULg

in African Literature Today (2014), 32

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See detailTMS can selectively activate and condition two different sets of excitatory synaptic inputs to corticospinal neurons in humans
Sommer, Martin; D'Ostilio, Kevin ULg; Cioccia, Matteo et al

Poster (2014, November)

Background: Current protocols or repetitive transcranial magnetic stimulation (rTMS) induce mixed facilitatory and inhibitory effects. More selective, quasi-monophasic high-frequency stimulators now ... [more ▼]

Background: Current protocols or repetitive transcranial magnetic stimulation (rTMS) induce mixed facilitatory and inhibitory effects. More selective, quasi-monophasic high-frequency stimulators now become available. We sought to investigate the impact of current direction and pulse width on intermittent theta burst stimulation (iTBS) effects on human motor cortex excitability. Also, we estimated strength-duration time constants from motor threshold and input-output (IO) curves for PA and AP orientations. Methods: We stimulated the dominant hand representation of the motor cortex in 15 healthy subjects, using “unidirectional biphasic” pulses generated by a controllable TMS machine (cTMS-3, Rogue Resolutions Ltd., Cardiff, UK), connected to a standard figure-8 coil. iTBS was applied conventionally, using 20 sequences of 2 seconds iTBS (10 bursts at 5 Hz burst repetition frequency, each burst consisting of 3 pulses of 80 % AMT intensity repeated at 50 Hz frequency). In separate sessions pulses differing in current direction and shape were applied: a) posterio-anterior (PA) current direction in the brain, 75 μs (iTBS_PA75). b) AP current direction, 45 μs (iTBS_AP45). Before and for 30 minutes after iTBS, we monitored the modulation of motor evoked potential (MEP) amplitude from the dominant first dorsal interosseus using conventional, monophasic, suprathreshold pulses generated by a Magstim 2002 stimulator, inducing PA currents in the brain, at 0.2 Hz frequency. In an additional study on ten healthy subjects, we investigated the effect the two coil orientations with three different pulse widths (30, 60 and 120 μs) on the IO curve and the latency of the motor evoked potentials (MEPs). Results: iTBS_AP45 yielded a pronounced and slightly delayed inhibition of MEP amplitude in all but one subjects, it was unrelated to the MEP latency differences. iTBS_PA75 had a variable and inconsistent effect that was in part related to the latency differenceAP-LM , in that long latency differences were correlated with the induction of inhibition rather than facilitation. We found a longer time constant for AP than PA orientation. MEP latencies yielded an interaction between pulse width and orientation, due mainly to longer onset latencies following AP stimuli of short duration. Conclusions: Current direction influences the outcome of iTBS, with a preference for AP currents. PA and AP stimuli activate the axons of neurones with different time constants. Those activated by AP pulses excite corticospinal outputs with a longer latency than those activated by PA pulses. AP pulses of short duration recruit long latency inputs most selectively. [less ▲]

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See detailEstetrol attenuates neonatal hypoxic–ischemic brain injury
Tskitishvili, Ekaterine ULg; Nisolle, Michelle ULg; Munaut, Carine ULg et al

in Experimental Neurology (2014), 261

Estetrol (E4) is a recently described natural estrogen with four hydroxyl-groups that is synthesized exclusively during pregnancy by the human fetal liver. It has important antioxidative activity. The aim ... [more ▼]

Estetrol (E4) is a recently described natural estrogen with four hydroxyl-groups that is synthesized exclusively during pregnancy by the human fetal liver. It has important antioxidative activity. The aim of the present study was to define the importance of E4 in the attenuation of neonatal hypoxic-ischemic encephalopathy. Antioxidative effect of 650μM, 3.25mM and 6.5mM E4 on primary hippocampal cell cultures was studied before/after H202-induced oxidative stress. To examine oxidative stress and cell viability, lactate dehydrogenase activity and cell proliferation colorimetric assays were performed. To study the neuroprotective and therapeutic effects of E4 in vivo neonatal hypoxic-ischemic encephalopathy model of 7-day-old newborn rat pups was used. The neuroprotective and therapeutic effects of estetrol before/after hypoxic-ischemic insult was studied in 1mg/kg/day, 5mg/kg/day, 10mg/kg/day, 50mg/kg/day E4 pretreated/treated groups and compared with the sham and the vehicle treated groups. The body temperature of the rat pups was examined along with their body and brain weights. Brains were studied at the level of the hippocampus and cortex. Intact cell counting and expressions of microtubule-associated protein-2, doublecortin and vascular-endothelial growth factor were evaluated by histo- and immunohistochemistry. ELISAs were performed on blood samples to detect concentrations of S100B and glial fibrillary acidic protein as brain damage markers. This work reveals for the first time that E4 significantly decreases LDH activity and enhances cell proliferation in primary hippocampal neuronal cell cultures in vitro, and decreases the early gray matter loss and promotes neuro- and angiogenesis in vivo. [less ▲]

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See detailImpact of the dialysis membrane on the Vitamin D metabolims markers
CAVALIER, Etienne ULg; DUBOIS, Bernard ULg; Urena, Pablo et al

Poster (2014, November)

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See detailA BCool magnetic snapshot survey of solar-type stars
Marsden, S.C.; Petit, P.; Jeffers, S.V. et al

in Monthly Notices of the Royal Astronomical Society (2014), 444

We present the results of a major high-resolution spectropolarimetric BCool project magnetic survey of 170 solar-type stars. Surface magnetic fields were detected on 67 stars, with 21 classified as mature ... [more ▼]

We present the results of a major high-resolution spectropolarimetric BCool project magnetic survey of 170 solar-type stars. Surface magnetic fields were detected on 67 stars, with 21 classified as mature solar-type stars, a result that increases by a factor of 4 the number of mature solar-type stars on which magnetic fields have been observed. In addition, a magnetic field was detected for 3 out of 18 of the subgiant stars surveyed. For the population of K-dwarfs, the mean value of |Bl| (|Bl|mean) was also found to be higher (5.7 G) than |Bl|mean measured for the G-dwarfs (3.2 G) and the F-dwarfs (3.3 G). For the sample as a whole, |Bl|mean increases with rotation rate and decreases with age, and the upper envelope for |Bl| correlates well with the observed chromospheric emission. Stars with a chromospheric S-index greater than about 0.2 show a high magnetic field detection rate and so offer optimal targets for future studies. This survey constitutes the most extensive spectropolarimetric survey of cool stars undertaken to date, and suggests that it is feasible to pursue magnetic mapping of a wide range of moderately active solar-type stars to improve our understanding of their surface fields and dynamos. [less ▲]

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See detailIsotopic tracing of sediment components that are assimilated by epibiontic juveniles of Holothuria scabra (Holothuroidea)
Plotieau, Thomas; Lepoint, Gilles ULg; Lavitra, Thiery et al

in Journal of the Marine Biological Association of the United Kingdom (2014), 94(7), 1485-1490

Despite H. scabra’s wide distribution and status as one of the best candidates for sustaining the development of tropical sea cucumber aquaculture, very few data are available regarding the organic ... [more ▼]

Despite H. scabra’s wide distribution and status as one of the best candidates for sustaining the development of tropical sea cucumber aquaculture, very few data are available regarding the organic fraction it assimilates in practice. In this study we report experimental results where H. scabra’s diet was supplemented with various 15N-labelled organic fractions of sediment. We used juveniles weighing between 38- 88 mg at the beginning of the experiment (ca. 2 cm long and 30 days old). Their growth was measured over a four week period and their 15N composition recorded. The results showed that H. scabra juveniles assimilated all added organic components from both dissolved and particulate fractions of the sediment. Bacteria seem to be an important food source for juveniles, even more so than microphytobenthos (diatoms). [less ▲]

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See detailLe matérialisme est-il mort ? petite critique de l'idéalisme critique
Frère, Bruno ULg

in Frère, Bruno (Ed.) Le tournant de la théorie critique (2014)

This article is concerned with the lack of effectiveness of contemporary critical theories in explaining the conditions for social change. These theories, I would argue, continue to rely on a narrow ... [more ▼]

This article is concerned with the lack of effectiveness of contemporary critical theories in explaining the conditions for social change. These theories, I would argue, continue to rely on a narrow construction of social actors. Indeed from Lukács to Bourdieu or even Habermas, many significant intellectual developments have taken place which continue to be based on one key assumption: that individuals (workers, social actors, etc.) unconsciously reproduce the social structures of capitalism whilst being alienated by them. They accept the conditions enforced on them and no longer seek to rebel against a system which impoverishes not only their work and culture, but also their soul and their creativity. What is more: they ensure the reproduction of the system by seeking to engage in mass consumption at any cost, or by glorifying the dominant values. In this paper I would like to show that today, no new critical perspective has emerged out of this negative representation of the world. Indeed, critical works present ‘man’ living here and now as nothing more than a deeply bastardized being, corrupted, denatured, soiled by a civilizing process. What we have is in effect a social actor who, in Rousseau’s philosophical tradition, has been perverted by a civilizing process informed by modernity or capitalism. This view of social actors rests on a form of disgust towards the world. [less ▲]

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See detailCompte rendu de "Où est passé la critique sociale", P. Corcuff, La découverte, 2013
Frère, Bruno ULg

in SociologieS (2014)

L’ouvrage dont Philippe Corcuff nous suggère ici un grand résumé est stimulant à plus d’un titre. Comme à son habitude l’auteur fait montre d’une étonnante faculté à circuler entre les différents espaces ... [more ▼]

L’ouvrage dont Philippe Corcuff nous suggère ici un grand résumé est stimulant à plus d’un titre. Comme à son habitude l’auteur fait montre d’une étonnante faculté à circuler entre les différents espaces de réflexion de l’agir humain, balayant tour à tour le champ de la sociologie, de la philosophie, du cinéma, de la littérature, de l’engagement social et politique ou de la culture populaire. Passant de Michel Jonaz à Foucault, de Weber à Al Pacino, de Marcos à Magris, Corcuff jongle assez magistralement avec des univers distincts que nos habitudes intellectuelles aiment séparer tantôt par souci prétendu de « scientificité » tantôt parce que, bon gré mal gré, nos esprits de chercheurs en sciences humaines ont été configurés de telle sorte que les passerelles entre divers champs de réflexions possibles (artistiques, politiques, sociologiques, etc.) ne se construisent même plus. Je voudrais donc ouvrir la discussion autour de Où est passé la critique sociale ? en saluant l’audace des ponts entrepris par Philippe Corcuff. Que l’on accepte de le suivre sur chacun d’entre eux ou pas n’enlève rien à la qualité de cette tentative intellectuellement risquée (tant les espaces parcourus sont vastes) à l’heure où la doxa académique, comme dirait Bourdieu, voudrait que nous nous enfermions tous exclusivement dans l’ultra-spécialisation scientifique de micro-catégories du savoir rassemblées dans une case de la sous-spécialité de la discipline que nous avons choisi. Cela afin de parvenir à pointer du doigt un détail qui sera jugé suffisamment original par les rares pairs aussi spécialisés que nous pour décrocher le graal d’une publication dans une sacro-sainte revue rankée. Ainsi, Corcuff semble nous dire : je ne suis pas spécialiste des gender studies mais j’ose évoquer le féminisme. Je ne suis pas spécialiste de la Grèce Antique mais j’ose citer Aristote. On se moque du contenu des textes de tel chanteur populaire, mais j’ose indiquer en quoi il recèle, au même titre que le féminisme ou Aristote, des ressources pour construire une sociologie ou, plus simplement, une esquisse de pensée analytique. Corcuff démontre qu’il est possible de rompre les barrières, de fréquenter des terres improbables pour faire naître le plaisir de la réflexion. Et c’est très heureux. Cette appréciation globale posée, je voudrais à présent entrer dans le vif du sujet et structurer mon commentaire en deux temps. Le premier voudrait insister sur les deux principales qualités des deux textes. De par la variété des paradigmes sociologiques, philosophiques, anthropologiques ou historiques convoqués, Où est passée la critique sociale ? et son résumé dévoilent un intérêt pédagogique singulier pour tout qui désire fréquenter ces disciplines. D’autre part, l’un des trois axes de l’ouvrage repérés par Corcuff dans son grand résumé mérite pour sa part clairement l’intérêt des spécialistes contemporains de la critique sociale. Le second temps de mon commentaire traitera alors de l’écueil que je pense cette fois déceler dans le résumé et l’ouvrage. Cet écueil illustre d’ailleurs une légère insatisfaction ressentie à l’égard de plusieurs ouvrages de l’auteur, insatisfaction précisément due à la frustration de ne pas voir l’originalité de sa démarche être conduite à son terme. Pour le dire rapidement, je chercherai à indiquer que, d’une certaine manière, la tentative de Corcuff a le défaut de ses qualités : il en fait trop et trop peu à la fois. Tout se passe comme si l’ouvrage – et le résumé – n’étaient qu’un succession de notes éparses qui se succèdent au sujet d’un très grand nombre d’auteurs, cités parfois lapidairement, souvent très rapidement, sur un concept ou l’autre, jamais développé de façon systématique, en arguant qu’au bout du compte, la démarche se justifie par la légitimité du bricolage en sociologie. A ce titre, l’ouvrage peut parfois apparaître redondant. Il semble en effet ressasser tout du long la même idée (intéressante au demeurant) d’une sociologie comme boîte à outil, assumant son incomplétude et ses insuffisances, en la déclinant il est vrai sous plusieurs angles. Ceci sans jamais véritablement entrer dans le vif du sujet et entreprendre soit l’approfondissement théorique de son intuition fondamentale soit son application empirique dans une enquête approfondie. [less ▲]

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See detailComparison of the Decomposition VOC Profile during Winter and Summer in a Moist, Mid-latitude (Cfb) Climate
Forbes, Shari L.; Perrault, Katelynn A.; Stefanuto, Pierre-Hugues ULg et al

in PLoS ONE (2014), 9(e113681), 1-11

The investigation of volatile organic compounds (VOCs) associated with decomposition is an emerging field in forensic taphonomy due to their importance in locating human remains using biological detectors ... [more ▼]

The investigation of volatile organic compounds (VOCs) associated with decomposition is an emerging field in forensic taphonomy due to their importance in locating human remains using biological detectors such as insects and canines. A consistent decomposition VOC profile has not yet been elucidated due to the intrinsic impact of the environment on the decomposition process in different climatic zones. The study of decomposition VOCs has typically occurred during the warmer months to enable chemical profiling of all decomposition stages. The present study investigated the decomposition VOC profile in air during both warmer and cooler months in a moist, mid-latitude (Cfb) climate as decomposition occurs year-round in this environment. Pig carcasses (Sus scrofa domesticus L.) were placed on a soil surface to decompose naturally and their VOC profile was monitored during the winter and summer months. Corresponding control sites were also monitored to determine the natural VOC profile of the surrounding soil and vegetation. VOC samples were collected onto sorbent tubes and analyzed using comprehensive two-dimensional gas chromatography – time-of-flight mass spectrometry (GC6GC-TOFMS). The summer months were characterized by higher temperatures and solar radiation, greater rainfall accumulation, and comparable humidity when compared to the winter months. The rate of decomposition was faster and the number and abundance of VOCs was proportionally higher in summer. However, a similar trend was observed in winter and summer demonstrating a rapid increase in VOC abundance during active decay with a second increase in abundance occurring later in the decomposition process. Sulfur-containing compounds, alcohols and ketones represented the most abundant classes of compounds in both seasons, although almost all 10 compound classes identified contributed to discriminating the stages of decomposition throughout both seasons. The advantages of GC6GC-TOFMS were demonstrated for detecting and identifying trace levels of VOCs, particularly ethers, which are rarely reported as decomposition VOCs. [less ▲]

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See detailAnalysing spatiotemporal changes in sediment contamination
Richir, Jonathan ULg; Pini, Jennifer; White, Shannon et al

Poster (2014, November)

Coastal environments are subjected to anthropogenic threats, of which pollution by trace elements (TEs). They remain chemicals of concern because of their toxicity, their ability to be concentrated in ... [more ▼]

Coastal environments are subjected to anthropogenic threats, of which pollution by trace elements (TEs). They remain chemicals of concern because of their toxicity, their ability to be concentrated in biota and their persistence in sediment. Aware of these threats, monitoring agencies perform large environmental surveys. However, the databases generated often remain underexploited, even though they represent an important source of information for scientists. As a case study, we focused on the highly industrialized and developed coastal area of the Solent, south coast of the UK, which is also a European Marine site with protected habitats and species. To date, no scientific-based spatiotemporal trend has been published regarding its pollution in TEs. But mining of existing databases requested from the Environmental Agency and the Marine Environment Monitoring and Assessment National database showed that sediment from 32 sites were/are indeed monitored for that purpose, covering a 22 years period (1992-2013). Temporal trend analysis showed that sediment contamination significantly decreased during that time interval (45 % decrease in median). However, all TEs still show concentrations above Sediment Quality Guidelines. Important spatial variability is also present, presumably linked to the distribution of pollutant anthropogenic sources. Taken together, these data have been used to provide stakeholders with relevant scientific based tools, i.e. GIS maps of the contamination in TEs in the Solent. This regional-level assessment enables local stakeholders to create bridges between environmental scientists and local authorities and valorizes the existing databases, for future governance at the regional and national scales. [less ▲]

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See detailMapping French terms in a Belgian guideline on heart failure to international classifications and nomenclatures: the devil is in the detail.
Jamoulle, Marc ULg; Cardillo, Elena; Roumier, Joseph et al

in Informatics in Primary Care (2014), 4

Introduction: With growing sophistication of eHealth platforms, the ability increases to share medical information across patients, health care providers, institutions and across borders. This implies ... [more ▼]

Introduction: With growing sophistication of eHealth platforms, the ability increases to share medical information across patients, health care providers, institutions and across borders. This implies more stringent demands on the quality of data-entry at the point-of-care. Non-native English speaking general practitioners experience difficulties in interacting with international classification systems and nomenclatures to facilitate the secondary use of their data and to ensure semantic interoperability. Aim: To identify words and phrases pertaining to the heart failure domain and to explore the difficulties in mapping to corresponding concepts in ICPC-2, ICD-10, SNOMED-CT, and UMLS. Methods: The medical concepts in a Belgian guideline for General Practitioners (GPs) in its French version were extracted manually and coded first in ICPC-2, then ICD-10 by a physician, an expert in classification systems. In addition, mappings were sought with SNOMED-CT and UMLS concepts, using the UMLS SNOMED-CT browser. Results: We retained 143 words and phrases, of which 128 referred to a single concept (1-to-1 mapping), while 15 referred to 2 or more concepts (1-to-n mapping to ICPC rubrics or to the other nomenclatures). In the guideline, words or phrases were often too general for adequate correspondence. Marked discrepancy between semantic tags and types was found. Conclusion: This study illustrates the variability of the various international classifications and nomenclatures, the need for structured guidelines with more attention to precise wording, and the need for classification expertise embedded in sophisticated terminological resources. End-users need support to perform their clinical work in their own language, while still assuring standardized and semantic interoperable medical registration. Collaboration between computational linguists, knowledge engineers, health informaticians and domain experts is needed. [less ▲]

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See detailLes inhibiteurs de la PSCK9: une innovation majeure dans le traitement des dyslipidémies ?
PAQUOT, Nicolas ULg

in ABD- le supplément du médecin (2014), 57(6), 6-7

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See detailInfinite self-shuffling words
Charlier, Emilie ULg; Kamae, Teturo; Puzynina, Svetlana et al

in Journal of Combinatorial Theory - Series A (2014), 128

In this paper we introduce and study a new property of infinite words: An infinite word x, with values in a finite set A, is said to be k-self-shuffling (k≥2) if there exists a shuffle of k copies of x ... [more ▼]

In this paper we introduce and study a new property of infinite words: An infinite word x, with values in a finite set A, is said to be k-self-shuffling (k≥2) if there exists a shuffle of k copies of x which produces x. We are particularly interested in the case k=2, in which case we say x is self-shuffling. This property of infinite words is shown to be independent of the complexity of the word as measured by the number of distinct factors of each length. Examples exist from bounded to full complexity. It is also an intrinsic property of the word and not of its language (set of factors). For instance, every aperiodic word contains a non-self-shuffling word in its shift orbit closure. While the property of being self-shuffling is a relatively strong condition, many important words arising in the area of symbolic dynamics are verified to be self-shuffling. They include for instance the Thue–Morse word fixed by the morphism 0↦01, 1↦10. As another example we show that all Sturmian words of intercept 0<ρ<1 are self-shuffling (while those of intercept ρ=0 are not). Our characterization of self-shuffling Sturmian words can be interpreted arithmetically in terms of a dynamical embedding and defines an arithmetic process we call the stepping stone model. One important feature of self-shuffling words stems from their morphic invariance: The morphic image of a self-shuffling word is self-shuffling. This provides a useful tool for showing that one word is not the morphic image of another. In addition to its morphic invariance, this new notion has other unexpected applications particularly in the area of substitutive dynamical systems. For example, as a consequence of our characterization of self-shuffling Sturmian words, we recover a number theoretic result, originally due to Yasutomi, on a classification of pure morphic Sturmian words in the orbit of the characteristic. [less ▲]

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See detailLumière et Patrimoine, Lumière et Paradoxes - Préface
Elsen, Catherine ULg

in Elsen, Catherine; Luczak, Dorothée; Mambourg, Paul-Henri (Eds.) et al Lumière et Patrimoine, eBook (2014)

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See detailGBS and antibiotic resistance: threat to therapy
MELIN, Pierrette ULg

in XIX Lancefield International Symposium on Streptococci and Streptococcal Diseases, Program and Abstract book (2014, November)

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See detailPrediction of mean and turbulent kinetic energy in rectangular shallow reservoirs
Camnasio, Erica; Erpicum, Sébastien ULg; Archambeau, Pierre ULg et al

in Engineering Applications of Computational Fluid Mechanics (2014), 8(4),

Shallow rectangular reservoirs are common structures in urban hydraulics and river engineering. Despite their simple geometry, complex symmetric and asymmetric flow fields develop in such reservoirs ... [more ▼]

Shallow rectangular reservoirs are common structures in urban hydraulics and river engineering. Despite their simple geometry, complex symmetric and asymmetric flow fields develop in such reservoirs, depending on their expansion ratio and length-to-width ratio. The original contribution of this study is the analysis of the kinetic energy content of the mean flow, based on UVP velocity measurements carried throughout the reservoir in eleven different geometric configurations. A new relationship is derived between the specific mean kinetic energy and the reservoir shape factor. For most considered geometric configurations, leading to four different flow patterns, the experimentally observed flow fields and mean kinetic energy contents are successfully reproduced by an operational numerical model based on the depth-averaged flow equations and a two-length-scale k-e turbulence closure. The analysis also highlights the better performance of this depth-averaged k-e model compared to an algebraic turbulence model. Finally, the turbulent kinetic energy in the reservoir is derived from the experimental measurements and the corresponding numerical predictions based on the k-e model agree satisfactorily in the main jet but not in the recirculation zones. [less ▲]

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See detailDissensus, n°7. Dossier "Technique et politique" (Edition en cours)
Pieron, Julien ULg

Book published by PoPuPS (2014)

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