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See detailA Partial Least Squares Analysis of the self reference effect in Alzheimer's disease: A reply to Irish
Genon, Sarah ULg; Bastin, Christine ULg; Angel, Lucie et al

in Cortex : A Journal Devoted to the Study of the Nervous System & Behavior (2014), 54

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See detailThe self-report Version of the LSAS-CA: Psychometric Properties of the French Version in a non-clinical adolescent sample
Schmits, Emilie ULg; Heeren, Alexandre; Quertemont, Etienne ULg

in Psychologica Belgica (2014), 54(2),

The Liebowitz Social Anxiety Scale (LSAS) is one of the most popular measures of social anxiety in adults. The LSAS has been adapted for clinical assessment of children and adolescents (LSAS-CA). The ... [more ▼]

The Liebowitz Social Anxiety Scale (LSAS) is one of the most popular measures of social anxiety in adults. The LSAS has been adapted for clinical assessment of children and adolescents (LSAS-CA). The psychometric properties of the self-report version of the LSAS-CA (LSAS-CA-SR) have been investigated in a Spanish population. However, no study to date has adapted and validated this scale in French. The purpose of this study was to develop a French version of the LSAS-CA-SR and to assess its score reliability and structural validity in a French-speaking community sample. The sample was made up of 1,343 teenagers from secondary schools, aged between 14 and 18 years. Confirmatory factor analyses established the structural validity of the French version of the LSAS-CA-SR and good psychometric properties, including reliable internal consistency, were observed. [less ▲]

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See detailCannabis et anxiété sociale chez les adolescents : Effets recherchés et ressentis
Schmits, Emilie ULg

Book published by Editions Universitaires Européennes (2014)

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See detailThe mitochondrial respiratory chain of the secondary green alga Euglena gracilis shares many additional subunits with parasitic Trypanosomatidae.
Perez, Emilie ULg; Lapaille, Marie; Degand, Herve et al

in Mitochondrion (2014)

The mitochondrion is an essential organelle for the production of cellular ATP in most eukaryotic cells. It is extensively studied, including in parasitic organisms such as trypanosomes, as a potential ... [more ▼]

The mitochondrion is an essential organelle for the production of cellular ATP in most eukaryotic cells. It is extensively studied, including in parasitic organisms such as trypanosomes, as a potential therapeutic target. Recently, numerous additional subunits of the respiratory-chain complexes have been described in Trypanosoma brucei and Trypanosoma cruzi. Since these subunits had apparently no counterparts in other organisms, they were interpreted as potentially associated with the parasitic trypanosome lifestyle. Here we used two complementary approaches to characterise the subunit composition of respiratory complexes in Euglena gracilis, a non-parasitic secondary green alga related to trypanosomes. First, we developed a phylogenetic pipeline aimed at mining sequence databases for identifying homologs to known respiratory-complex subunits with high confidence. Second, we used MS/MS proteomics after two-dimensional separation of the respiratory complexes by Blue Native- and SDS-PAGE to both confirm in silico predictions and to identify further additional subunits. Altogether, we identified 41 subunits that are restricted to E. gracilis, T. brucei and T. cruzi, along with 48 classical subunits described in other eukaryotes (i.e. plants, mammals and fungi). This moreover demonstrates that at least half of the subunits recently reported in T. brucei and T. cruzi are actually not specific to Trypanosomatidae, but extend at least to other Euglenozoa, and that their origin and function are thus not specifically associated with the parasitic lifestyle. Furthermore, preliminary biochemical analyses suggest that some of these additional subunits underlie the peculiarities of the respiratory chain observed in Euglenozoa. [less ▲]

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See detailAssociation of IL33-IL-1 receptor-like 1 (IL1RL1) pathway polymorphisms with wheezing phenotypes and asthma in childhood.
Savenije, Olga E.; Mahachie John, Jestinah ULg; Granell, Raquel et al

in The Journal of allergy and clinical immunology (2014)

BACKGROUND: Genome-wide association studies identified IL33 and IL-1 receptor-like 1 (IL1RL1)/IL18R1 as asthma susceptibility loci. IL33 and IL1RL1 constitute a single ligand-receptor pathway. OBJECTIVE ... [more ▼]

BACKGROUND: Genome-wide association studies identified IL33 and IL-1 receptor-like 1 (IL1RL1)/IL18R1 as asthma susceptibility loci. IL33 and IL1RL1 constitute a single ligand-receptor pathway. OBJECTIVE: In 2 birth cohorts, the Prevalence and Incidence of Asthma and Mite Allergy (PIAMA) study and Avon Longitudinal Study of Parents and Children (ALSPAC), we analyzed associations of longitudinal wheezing phenotypes and asthma with single nucleotide polymorphisms (SNPs) of 8 genes encoding IL-33, IL1RL1, its coreceptor IL1RAcP, its adaptors myeloid differentiation primary response gene 88 (MyD88) and Toll-IL-11 receptor domain containing adaptor protein (TIRAP), and the downstream IL-1 receptor-associated kinase 1, IL-1 receptor-associated kinase 4, and TNF receptor-associated factor 6 (TRAF6). Furthermore, we investigated whether SNPs in this pathway show replicable evidence of gene-gene interaction. METHODS: Ninety-four SNPs were investigated in 2007 children in the PIAMA study and 7247 children in ALSPAC. Associations with wheezing phenotypes and asthma at 8 years of age were analyzed in each cohort and subsequently meta-analyzed. Gene-gene interactions were assessed through model-based multifactor dimensionality reduction in the PIAMA study, and gene-gene interactions of 10 SNP pairs were further evaluated. RESULTS: Intermediate-onset wheeze was associated with SNPs in several genes in the IL33-IL1RL1 pathway after applying multiple testing correction in the meta-analysis: 2 IL33 SNPs (rs4742170 and rs7037276), 1 IL-1 receptor accessory protein (IL1RAP) SNP (rs10513854), and 1 TRAF6 SNP (rs5030411). Late-onset wheeze was associated with 2 IL1RL1 SNPs (rs10208293 and rs13424006), and persistent wheeze was associated with 1 IL33 SNP (rs1342326) and 1 IL1RAP SNP (rs9290936). IL33 and IL1RL1 SNPs were nominally associated with asthma. Three SNP pairs showed interaction for asthma in the PIAMA study but not in ALSPAC. CONCLUSIONS: IL33-IL1RL1 pathway polymorphisms are associated with asthma and specific wheezing phenotypes; that is, most SNPs are associated with intermediate-onset wheeze, a phenotype closely associated with sensitization. We speculate that IL33-IL1RL1 pathway polymorphisms affect development of wheeze and subsequent asthma through sensitization in early childhood. [less ▲]

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See detailReaching the 1% accuracy level on stellar mass and radius determinations from asteroseismology
Van Grootel, Valérie ULg; Charpinet, Stephane; Fontaine, Gilles et al

in Proceedings of the International Astronomical Union (2014), 301

Asteroseismic modeling of subdwarf B (sdB) stars provides measurements of their fundamental parameters with a very good precision; in particular, the masses and radii deter- mined from asteroseismology ... [more ▼]

Asteroseismic modeling of subdwarf B (sdB) stars provides measurements of their fundamental parameters with a very good precision; in particular, the masses and radii deter- mined from asteroseismology are found to typically reach a precision of 1% containing various uncertainties associated with their inner structure and the underlying microphysics (composition and transition zones profiles, nuclear reaction rates, etc.). Therefore, the question of the accuracy of the stellar parameters derived by asteroseismology is legitimate. We present here the seismic modeling of the pulsating sdB star in the eclipsing binary PG 1336-018, for which the mass and the radius are independently and precisely known from the modeling of the reflection/irradiation effect and the eclipses observed in the light curve. This allows us to quantitatively evaluate the reliability of the seismic method and test the impact of uncertainties in our stellar models on the derived parameters. We conclude that the sdB star parameters inferred from asteroseismology are precise, accurate, and robust against model uncertainties. [less ▲]

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See detailSartre, les passions de la liberté. Phénoménologie, politique, savoirs critiques
Cormann, Grégory ULg

Book published by Peter Lang (2014)

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See detailBone forming agents for the management of osteoporosis
Reginster, Jean-Yves ULg; Neuprez, A.; Beaudart, Charlotte ULg et al

in Panminerva medica (2014)

Osteoporotic fractures are a major cause of morbidity in the population. Anti-resorptive agents have been, for more than 15 years, the mainstay of osteoporosis treatment worldwide. However, these ... [more ▼]

Osteoporotic fractures are a major cause of morbidity in the population. Anti-resorptive agents have been, for more than 15 years, the mainstay of osteoporosis treatment worldwide. However, these medications provide only limited fracture reduction and may be linked to skeletal and non-skeletal long-term safety concerns. Therefore, some patients are considered candidates for bone-forming agents because they remain severely osteoporotic or because they failed antiresorptive therapy. Over the last decade, a particular interest was shown in the developmentofmedicationsabletoincreaseosteoblastsnumber,lifespan or activity, hence stimulating bone formation Peptides from the parathyroid hormone family and strontium ranelate were shown to significantly reduce fracture rates but strontium ranelate is no longer an option for treating osteoporosis because of its safety profile. New therapeutic options, including monoclonal antibodies against sclerostin seem to be promising but their role in the armamentarium of osteoporosis will depend on the results of the current phase 3 studies, assessing antifracture efficacy and long-term safety. [less ▲]

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See detailPrevalence of sarcopenia according to different diagnostic tools
Beaudart, Charlotte ULg; Buckinx, Fanny ULg; Slomian, Justine ULg et al

in Journal of Frailty & Aging (2014), 3(1), 43

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See detailEvolution over two years of functional and motor abilities among nursing home residents
Buckinx, Fanny ULg; Beaudart, Charlotte ULg; Slomian, Justine ULg et al

in Journal of Frailty & Aging (2014), 3(1), 45

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See detailaktives Affix
Münzberg, Franziska ULg

in Schierholz, Stefan J.; Dürscheid, Christa (Eds.) Grammatik - Formenlehre (2014)

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See detailSaisir l’évaluation de l’université en actes : interprétations et appropriations des parties prenantes.
Charlier, Nathan ULg; Vangeebergen, Thomas ULg

in Fallon, Catherine; Leclercq, Bruno (Eds.) Leurres de la qualité dans l’enseignement supérieur. Variations internationales sur un thème ambigu (2014)

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See detailSustainable intensification in Benin: myth or realiy? Lessons from organic cotton and cotton made in Africa systems of production.
Assogba, Sonagnon Claude-Gervais ULg; Tossou, Cocou Rigobert; Lebailly, Philippe ULg

in International Journal of Agriculture Innovations and Research (2014), 2(5), 694-704

In agriculture, the concept of sustainable development emergence and its omnipresence in political discourses suggests that farming systems move toward systems considered as more environment-friendly and ... [more ▼]

In agriculture, the concept of sustainable development emergence and its omnipresence in political discourses suggests that farming systems move toward systems considered as more environment-friendly and human health-friendly. In Benin, cotton is one of the most sectors concerned by this transformation. Indeed, in spite of the importance of cotton in the economy of Benin, its sustainable production is nowadays threatened by conventional production approach. Various alternatives of production are developed and considered as more environment-friendly than the conventional production approach. This article analyses the sustainability of organic and cotton made in Africa (CmiA) production systems from the sustainable agricultural intensification theoretical perspective. Structured and non-structured interviews with individuals and focus groups were used to collect data from 90 organic cotton farmers of the municipality of Kandi, and 100 CmiA farmers of the municipality of Pehunco, one of the largest areas of cotton production in the North of Benin. Data were analyzed with methods of normative and relativist comparison, descriptive statistics and analysis of variance. Kolmogorov-Smirnov (K-S) test was used to verify the normality conditions and in some cases, logarithmic transformation was done to test the variance homogeneity. The comparison of means was done with the test of Least Significant Difference. It appears from the results that in the current condition of implementation, the alternatives system to conventional cotton production approach are not intensively sustainable. Soils fertility and pests’ management face enormous constraints and do not allow improvement of yields, economic performances, and environment protection. So, the sustainability of the alternative systems of cotton production is not guaranteed and can hardly become a reality if additional relevant conditions are not created [less ▲]

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See detailZirkumfix
Münzberg, Franziska ULg

in Schierholz, Stefan J.; Dürscheid, Christa (Eds.) Grammatik - Formenlehre (2014)

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See detailVorsilbe
Münzberg, Franziska ULg

in Schierholz, Stefan J.; Dürscheid, Christa (Eds.) Grammatik - Formenlehre (2014)

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See detailnominales Präfix
Münzberg, Franziska ULg

in Schierholz, Stefan J.; Dürscheid, Christa (Eds.) Grammatik - Formenlehre (2014)

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See detailThe value of disturbance-tolerant cercopithecine monkeys as seed dispersers in degraded habitats
Albert, Aurélie; McConkey, Kim; Savini, Tommaso ULg et al

in Biological Conservation (2014), 170

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See detailIntroduction
Van Schuylenbergh, Patricia; Lanneau, Catherine ULg; Plasman, Pierre-Luc

in Van Schuylenbergh, Patricia; Lanneau, Catherine; Plasman, Pierre-Luc (Eds.) L'Afrique belge aux XIXe et XXe siècles. Nouvelles recherches et perspectives en histoire coloniale (2014)

Detailed reference viewed: 19 (0 ULg)