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See detailProceedings of the 12th Workshop on Models and Algorithms for Planning and Scheduling Problems
Marchetti-Spaccamela, Alberto; Crama, Yves ULg; Goossens, Dries et al

Book published by KU Leuven (2015)

This volume contains abstracts of talks presented at the 12th Workshop on Models and Algorithms for Planning and Scheduling Problems (MAPSP 2015), held from June 8 to June 12, 2015, in La Roche-en-Ardenne ... [more ▼]

This volume contains abstracts of talks presented at the 12th Workshop on Models and Algorithms for Planning and Scheduling Problems (MAPSP 2015), held from June 8 to June 12, 2015, in La Roche-en-Ardenne, Belgium. MAPSP is a biennial workshop dedicated to all theoretical and practical aspects of scheduling, planning, and timetabling. The abstracts in this volume include 5 invited talks by Onno Boxma, Michel Goemans, Willem-Jan van Hoeve, Rolf Niedermeier, and Stephan Westphal, plus 88 contributed talks. [less ▲]

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See detailAssessing the passage of obstacles by fish. Concepts, design and application
Baudoin, Jean-Marc; Burgun, Vincent; Chanseau, Matthieu et al

Book published by Onema - Editeur: Véronique Barre (2015)

The fragmentation of habitats has been acknowledged for 30 years as one of the five main factors of biodiversity loss, in conjunction with pollution, overuse of natural resources, invasive species and ... [more ▼]

The fragmentation of habitats has been acknowledged for 30 years as one of the five main factors of biodiversity loss, in conjunction with pollution, overuse of natural resources, invasive species and climate change. Since then, public environmental policies have strived to restore the connectivity of natural habitats. That is particularly the case for water policy, which has made the ecological continuity of rivers a central element in policy planning, a quality element for monitoring programmes and one of the basic guidelines for river-basin management plans (RBMP). The time has thus come for decisions, with the resulting controversy given that any attempt to modify existing discontinuities impacts our perception of landscapes and various uses of aquatic environments. Given that there is, on average, at least one obstacle for every five kilometres of river in continental France, this issue concerns the entire country, its population and all water managers. That explains why it was necessary to have a single set of standardised procedures for selecting the work to be done on the basis of objective and comparable data. For the ecological continuity of fish, we now have the ICE method presented in this book, which describes obstacles in rivers and assesses the capacity of fish to overcome those obstacles during their upstream migration. The design, development and national deployment of this method required five years of intense, collective effort on the part of numerous scientists and the Onema local and regional offices. The method is the result of an outstanding multi-disciplinary approach involving both hydraulics and ecology, two disciplines that some people might see as irreconcilable, but that must work together synergistically in the effort to restore environments. The publication of this book in the Knowledge for action series marks the transition from the team that developed the method to the people who will use it to acquire better understanding of ecological continuity in rivers and as an operational tool in implementing water policy and enhancing biodiversity. [less ▲]

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See detailEGFR and NF-kB: partners in cancer
Shostak, Kateryna ULg; Chariot, Alain ULg

in Trends in Molecular Medicine (2015), 21

Oncogenic proteins cooperate to promote tumor development and progression by sustaining cell proliferation, survival and invasiveness. Constitutive EGFR and NF-kappaB activities are seen in multiple solid ... [more ▼]

Oncogenic proteins cooperate to promote tumor development and progression by sustaining cell proliferation, survival and invasiveness. Constitutive EGFR and NF-kappaB activities are seen in multiple solid tumors and combine to provide oncogenic signals to cancer cells. Understanding how these oncogenic pathways are connected is critical, given their role in intrinsic or acquired resistance to targeted anti-cancer therapies. We review molecular mechanisms by which both EGFR- and NF-kappaB-dependent pathways establish positive loops to increase their oncogenic potential. We also describe how NF-kappaB promotes resistance to EGFR inhibitors. [less ▲]

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See detailSmall-Angle Scattering in Porous Solids, an overview highlighting data analysis challenges
Gommes, Cédric ULg

Conference (2015, June)

Countless technologies and chemical processes make use of nanoporous materials: heterogeneous catalysis, including electrochemical reactions in fuel-cell electrodes, adsorption separation processes ... [more ▼]

Countless technologies and chemical processes make use of nanoporous materials: heterogeneous catalysis, including electrochemical reactions in fuel-cell electrodes, adsorption separation processes, kinetically selective membrane processes, are but a few examples. Nanopores are also relevant to natural processes as diverse as the weathering of rocks and ion transport through biological membranes.[1] Small-angle scattering of x-rays (SAXS) or neutrons (SANS) is one of the few experimental methods currently available for the in situ analysis of phenomena in this type of materials at the mesoscopic scale.[e.g. 2,3] In this presentation, we briefly review some recent applications of small-angle scattering to the in situ analysis of phenomena inside mesoporous solids. A particular focus is put on the data analysis challenges, whereby the scattered intensity is converted to real-space structures with nanometer resolution. [less ▲]

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See detailPrevenção quaternária: primeiro não causar dano - Editorial
Jamoulle, Marc ULg

in Revista Brasileira de Medicina de Família e Comunidade (2015), 10(35), 1-3

A prevenção clínica, sob a influência da saúde pública, foi organizada de forma cronológica, desde meados do século XX. No entanto, uma mudança de paradigma de uma ordem cronológica para um padrão ... [more ▼]

A prevenção clínica, sob a influência da saúde pública, foi organizada de forma cronológica, desde meados do século XX. No entanto, uma mudança de paradigma de uma ordem cronológica para um padrão construtivista fundamentado em uma relação preventiva de atendimento, oferece novas,reflexões à prática dos médicos. Essa mudança de paradigma traz à tona o conceito de prevenção quaternária, um olhar crítico sobre as atividades médicas, com ênfase na necessidade de não causar danos. A prevenção quaternária aborda a questão principal do que se constitui como ‘muita’ ou ‘pouca’ medicina. Ela é a quarta forma de prevenção de doenças, e também a quarta etapa de ação dos médicos de família [less ▲]

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See detailThe strength of multi-row models
Louveaux, Quentin ULg; Poirrier, Laurent; Salvagnin, Domenico

in Mathematical Programming Computation (2015), 7(2), 113-148

We develop a method for computing facet-defining valid inequalities for any mixed-integer set PJ. Our practical implementation does not return only facet- defining inequalities, but it is able to find a ... [more ▼]

We develop a method for computing facet-defining valid inequalities for any mixed-integer set PJ. Our practical implementation does not return only facet- defining inequalities, but it is able to find a separating cut whenever one exists. The separator is not comparable in speed with the specific cutting-plane generators used in branch-and-cut solvers, but it is general-purpose. We can thus use it to compute cuts derived from any reasonably small relaxation PJ of a general mixed- integer problem, even when there exists no specific implementation for computing cuts with PJ. Exploiting this, we evaluate, from a computational perspective, the usefulness of cuts derived from several types of multi-row relaxations. In particular, we present results with four different strengthenings of the two-row intersection cut model, and multi-row models with up to fifteen rows. We conclude that only fully-strengthened two-row cuts seem to offer a significant advantage over two-row intersection cuts. Our results also indicate that the improvement obtained by going from models with very few rows to models with up to fifteen rows may not be worth the increased computing cost. [less ▲]

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See detailUn air familier ? Sociohistoire des pollutions atmosphériques
Charvolin, Florian; Frioux, Stéphane; Kamoun, Léa et al

Book published by Presses des MINES (2015)

Pollutions au mercaptan, particules de moteur diesel dans l’air, odeurs de raffineries, rejets d’anhydrides sulfureux… nous avons tous périodiquement l’impression de vivre dans un monde irrespirable. Cet ... [more ▼]

Pollutions au mercaptan, particules de moteur diesel dans l’air, odeurs de raffineries, rejets d’anhydrides sulfureux… nous avons tous périodiquement l’impression de vivre dans un monde irrespirable. Cet air, si familier qu’il passe aussi inaperçu que le fait de le respirer, est devenu avec le progrès scientifique et l’industrialisation une affaire d’expertise et de politiques publiques. L’ouvrage montre comment l’air se manifeste dans la vie de nos concitoyens depuis le milieu du XIXe siècle : affaire de perception d’abord, de revendication ensuite, et finalement, depuis les années 1950, d’appareillage technique. La population est acteur à plus d’un titre de la politique de l’air, publique comme privée : elle multiplie les plaintes, s’élève contre la pollution chronique, est la destinataire d’informations techniques comme l’indice atmo, mène des actions locales pour lutter contre les gênes, etc. C’est ce que montre cet ouvrage dans une enquête qui associe historien, sociologue, politiste et géographe. Et l’on pourra ainsi se demander si mesurer l’air est une façon d’exprimer sa foi dans la maîtrise « sur » les problèmes environnementaux par la modernisation technique, ou bien si c’est le début d’une exploration plus démocratique de l’homme « dans » son environnement, avec le retour en grâce de la participation des habitants, comme ce fut récemment le cas dans la cartographie des odeurs. [less ▲]

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See detailLe marché des radicaux libres. Sur quelques conditions médiatiques de la posture « néo-réactionnaire ».
Durand, Pascal ULg

in Quaderni : la Revue de la Communication (2015), 87(printemps), 101-118

Years 1990-2000 could be characterized in France by the emergence of a current of thought and a nebula of intellectual actors collectively gathered under the label of the « New Reactionaries » since the ... [more ▼]

Years 1990-2000 could be characterized in France by the emergence of a current of thought and a nebula of intellectual actors collectively gathered under the label of the « New Reactionaries » since the publication of the controversial pamphlet, Le Rappel à l’ordre, by Daniel Lindenberg in 2002. Journalists, novelists, essayists, columnists, philosophers, showing a posture of refusal towards the « politically correct », the « moral left » and the « dominant ideology », they can be viewed as a kind of generic character, made up of peculiarities breaking away from any sociological assignment. The topics of this discourse tend to be analyzed from a point of view not included within the concerned polemical filed. The aim of this paper is to contribute to such an analysis by pointing out the transformations of the journalistic and publishing field from which the « new reactionaries » draw some of their powerful polemical efficiency. [less ▲]

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See detailLaTeX, un peu, beaucoup (8. Compteurs)
Dupont, Pascal ULg

in Losanges (2015)

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See detailDamage process sensitivity analysis using an XFEM-Level Set framework
Noël, Lise ULg; Duysinx, Pierre ULg; Maute, Kurt

in Proceedings of the 11th World Congress on Structural and Multidisciplinary Optimization (WCSMO-11) (2015, June)

Designing efficient and lightweight structures is a key objective for many industrial applications such as in aerospace or the automotive industry. To this end, composite materials are appealing as they ... [more ▼]

Designing efficient and lightweight structures is a key objective for many industrial applications such as in aerospace or the automotive industry. To this end, composite materials are appealing as they combine high stiffness and light weight. The main challenge slowing down the integration of such materials in real structures is their damage be- havior. The latter should be considered in the design process of the structures. This work focuses on developing a systematic approach to designing structures that can sustain an acceptable amount of degradation or exhibit a low sensitivity to damage. An optimization approach is chosen to achieve this goal. To deal with complex geometries and to allow for large shape modifications in the optimization process, the extended finite element method (XFEM) is advantageously combined with a level set description of geometry. The degradation of materials is modeled by using a non-local damage model, motivated by the work of James and Waisman on a density approach to topol- ogy optimization. To solve design problems with damage constraints by gradient-based optimization method, a sensitivity analysis of the damage process is developed. Damage propagation and growth is an irreversible pro- cess. Therefore, the path dependence of the structural response needs to be accounted for in the sensitivity analysis. In this paper, we present an analytical approach for efficiently and accurately evaluating the design sensitivities, considering both direct and adjoint formulations. Finally, the sensitivity analysis approach is studied with simple benchmark problems and compared with the results obtained by finite differences. [less ▲]

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See detailEvaluation de la culture de responsabilité des médecins whyers dans les CHU algériens
Bounazef, Djida ULg; Chabani, Smain

in Revue des Sciences Commerciales (2015)

Cet article permet de définir la personnalité du médecin algérien appartenant à la générationY travaillant au niveau des centres hospitalo-universitaires en Algérie. Le but est de déterminer si son ... [more ▼]

Cet article permet de définir la personnalité du médecin algérien appartenant à la générationY travaillant au niveau des centres hospitalo-universitaires en Algérie. Le but est de déterminer si son environnement de travail et le climat social interne des CHU permettent de valoriser au mieux son efficacité à travers son épanouissement au travail. Étant très tourné vers la vision à court terme et au changement de carrière, le médecin whyer représente un investissement risqué en vue de sa possibilité de départ pour cause de démotivation et d’environnement non favorable à son développement. L’étude de cas permet de faire une évaluation de la culture de responsabilité des médecins whyer safin d’induire leurs implications et engagements vis-à-vis de leurs CHU respectifs. Les résultats de l’étude insistent sur le manque de collaboration, d’échange et de compréhension entre la direction des CHU et les médecins whyers qui tombent dans un conflit générationnel qui impacte négativement l’intégration d’une culture de responsabilité. [less ▲]

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See detailThe central role of the thymus in the programming of immunological tolerance to neuroendocrine self: Implications for the pathogenesis of autoimmune diseases.

Geenen, Vincent ULg

Conference (2015, June)

Our studies have demonstrated that the thymus programs central self-tolerance to neuroendocrine functions through transcription of neuroendocrine-related genes in thymic epithelial cells (TECs). However ... [more ▼]

Our studies have demonstrated that the thymus programs central self-tolerance to neuroendocrine functions through transcription of neuroendocrine-related genes in thymic epithelial cells (TECs). However, thymic neuroendocrine precursors are not secreted but processed as the source of neuroendocrine self-antigens that are presented by thymic proteins of the major histocompatibility complex (MHC). This process, highly specific of the thymus, has allowed an integrated and harmonious coevolution of the neuroendocrine and immune systems when recombination-activating genes and the subsequent adaptive immune response have emerged in cartilaginous fishes some 450-500 millions years ago. All the members of the insulin gene family are expressed in murine TECs under the control of AutoImmune Regulator (AIRE) according a precise hierarchy: Igf2 >Igf1>Ins2>Ins1. Igf2 transcription is defective in TECs of autoimmune diabetes-prone BB rats, and tolerance to insulin is severely impaired in Igf2-/- mice as well as in Igf2-loxP/Foxn1-cre mice with Igf2 deletion targeted in TECs. In addition, the diabetogenic coxsackievirus B4 (CV-B4) is able to persistently infect human and murine TECs and to inhibit Igf2 transcription and IGF-2 synthesis in a murine medullary TEC line (coolaboration with D. Hober, Laboratory of Virology, CHRU and University of Lille 2, France). These studies show that: 1° IGF-2 is the dominant tolerogenic precursor of the family and mediates cross-tolerance to insulin; 2° a thymus dysfunction plays a crucial role in the development of the diabetogenic autoimmune response; and 3° a thymic infection by CV-B4 is implicated in type 1 diabetes (T1D) pathogenesis. Most probably due to its very low level of expression in the thymus, the protein insulin is highly immunogenic and is the primary autoantigen tackled in T1D. On the basis of the tolerogenic properties of IGF-2, we are currently working on the development of a negative/tolerogenic self-vaccine against T1D. [less ▲]

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See detailAuroral Morphologies of Jupiter and Saturn
Grodent, Denis ULg

Conference (2015, May 31)

We review the principal differences and similarities of the morphologies of Jupiter and Saturn's auroral emissions. We then show some examples of UV images that are expected to be acquired with Cassini ... [more ▼]

We review the principal differences and similarities of the morphologies of Jupiter and Saturn's auroral emissions. We then show some examples of UV images that are expected to be acquired with Cassini UVIS at Saturn and Juno UVS at Jupiter. [less ▲]

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See detailTowards an experiment based protocol for extracting and identifying residues
Cnuts, Dries ULg; Rots, Veerle ULg

Conference (2015, May 29)

Residue analysis has recently become a widely applied method in reconstructing the lifecycle of prehistoric stone tools. The identification of residues is traditionally based on the distinctive ... [more ▼]

Residue analysis has recently become a widely applied method in reconstructing the lifecycle of prehistoric stone tools. The identification of residues is traditionally based on the distinctive morphologies of the residue fragments by means of light microscopy. The majority of residue fragments, however, tend to have an amorphous structure and are therefore not easy to identify. In addition, some residue categories can only be detected by using transmitted light microscopy, which requires the extraction of residues from the tool’s surface. Yet another challenge is to determine whether the residues were deposited on the tool’s surface as a result of use or due to other processes. Here we present the results of an experimental study that addresses these methodological issues. Stone tools from a new experimental reference collection were used to test 6 different analytical methods: the observation of residues on stone tools with incident light microscopy, dry sampling using tweezers and brushes, wet sampling with micropipettes using distilled water and a tri-mixture of acetonitrile, ethanol and water, and extraction with an ultrasonic scaler or bath. The experiments demonstrate that the choice of a particular extraction procedure may influence the amount and types of residues that are extracted. This implies that the analytical method has an impact on the results of a residue analysis. Building on these data, we designed a new protocol, which was subsequently submitted to blind testing in order to test its accuracy and precision. Certain key attributes were also identified that may prove useful in distinguishing between use-related and natural residues. We discuss the importance of adapting analytical protocols to the research question of the study. [less ▲]

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See detailToward a more precise terminology for impact damage and an improved understanding of hunting weapons: First results from a large scale systematic experiment
Coppe, Justin ULg; Rots, Veerle ULg

Conference (2015, May 29)

Projectile points have recently taken an important place in debates on the complexity of Palaeolithic human behaviour. While the appearance of hunting weapons in the archaeological record was an important ... [more ▼]

Projectile points have recently taken an important place in debates on the complexity of Palaeolithic human behaviour. While the appearance of hunting weapons in the archaeological record was an important element in the past, current discussions focus a lot on the appearance of particular hunting methods. Distinctions are made between simple and complex weaponry, the latter assumed to be linked with modern humans only. While most of the identifications of hunting weapons in the archaeological record rely on the examination of so-called diagnostic impact damage, no reliable reference yet exist for distinguishing between hunting methods. We present the first results of a large-scale and systematic experiment that intends to address hunting weapons in a systematic way. A thorough survey of the literature has highlighted some existing ambiguity in current terminological frameworks for describing impact fractures. Based on our experiments, we propose some attributes that may be relevant for improving these terminologies. Attention will also be devoted to the design and conceptual framework of our experimental program and to some first results concerning the essential variables influencing damage formation. The overall goal is to improve our understanding of the different fracture phenomena and their variability in order to enhance the reliability of the identification of hunting weapons and perhaps of their projecting mode. [less ▲]

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See detailQuelles caractéristiques du passage à la retraite ont un impact sur la cognition du sujet âgé ? Résultats de la cohorte AMI
Grotz, Catherine ULg; Matharan, Fanny; Amieva, Hélène et al

Conference (2015, May 29)

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See detailTable-ronde autour de l'ouvrage : M. Hagelstein, "Origine et survivances des symboles. Warburg, Cassirer, Panofsky"
Hagelstein, Maud ULg

Scientific conference (2015, May 29)

Table-ronde - échange questions/réponses - avec la participation de : Muriel VAN VLIET, Raphaël GÉLY, Rudy STEINMETZ, Alievtina HERVY, Bruno LECLERCQ

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See detailFragmentation urbaine à travers les réseaux techniques
Cabrera Quispe, Juan Edson ULg

Doctoral thesis (2015)

Since about three decades ago, the networking services (water, energy, transport and telecommunications) are the subject of studies and mainly reforms (liberalization, privatization and concessions to ... [more ▼]

Since about three decades ago, the networking services (water, energy, transport and telecommunications) are the subject of studies and mainly reforms (liberalization, privatization and concessions to private companies, etc.) and also an important economic policy issue. However the possible effects of these reforms on the fragmentation or integration of urban societies are still poorly studied, although some studies (mainly on developing cities) support the thesis that there would be a growing urban fragmentation, reinforced by the dominant modes of implementing reforms network services. One of the most important theses about the subject is in a relatively recent development of the English authors Stephen Graham and Simon Marvin (2001). Their work generalizes the motion of fragmentation (splintering Urbanism) to all network services and a set of economic regions in the world. While this thesis presents consistency and validity - since it is known that the application of models of decentralization and liberalization of services has an effect on the fragmentation - the position of fragmentation due to centralized networks is inside a new analysis framework and still incomplete considering the absence of more empirical evidence. The thesis of fragmentation from centralized networks suggests that powerful factors are contributing to the disintegration of infrastructure, favoring the fragmentation of the social structure and material of cities. In fact, this breakdown of infrastructures makes possible many strategies of evasion; they are addressed to connect powerful users and valorized spaces, preventing the connection with less powerful users and poor spaces. These processes lead to the creation of spaces from different social networks, resulting in social elites living every day in places disconnected from the urban structure of the set (in gated communities, new complex people and other planned communities), as well as the lower classes, but the latter with the worst conditions. The main hypothesis of the "splintering Urbanism" argues that network services have an integrated character and are precisely the privatization and liberalization of services that contribute to the breakdown of network infrastructure and urban fragmentation feed. The control of networks from powerful coalitions of actors, separation and segmentation boost infrastructure in different network elements and service pack (2001: 141). This separation would occur across strategies "bypass" or "wrap" seeking to connect users, valuable or powerful places, and through discarding or dodge weaker users and worthless places. Our thesis "Urban Fragmentation through technical networks," confirms and reinforces the thesis made by Graham & Marvin, across expounding on the Cochabamba Bolivian context, a set of technical networks of small-scale or micro decentralized networks which are managed by autonomous social organizations that also fragment the territory without the need for "by pass" and the socio-spatial differentiation, but through the realization of strategies linked to autonomous administration and management of common and basic goods like water. This thesis demonstrates the existence of processes of spatial dislocation and loss of solidarity (main evils of urban fragmentation) across the dynamics of technical devices and decentralized networks infrastructure services from private-community water and small scale. However, our work describes in its urban development, territorial and environmental problems inside the phenomenon. The paper first presents a set of theories that attempt to explain the fragmentation and its particularities, then describes the socio-spatial formation of the study area whose characteristics allow this type of phenomenon, to arrive to a section that exposes all the particularities of the management water from public and local actors, analyzed from the environmental logic of urban water cycle, including the specifics of the main stage of study of this thesis, the municipality of Quillacollo in Cochabamba. From a spatial perspective, the thesis exhibits the characteristics of urban fragmentation across technical networks, exposing the details related to the organization of urban space as a result of processes of spatial dislocation, loss of solidarity and exercise of territoriality in small networks. It is concluded in a discussion about the validity of the strategies in terms of access to the resource, the possibilities of intervention and reflections about the power relationships among fragments and for water control. Finally, as a supplement, urban fragmentation through small technical networks, also allows to display the tensions between two ways of managing the territory (centralized view from the public sector and decentralized vision from local communities) highlighting the uncomfortable and marginalized urban planning position, but challenging the urbanism to recover to action on the highly fragmented contemporary cities with complex scenarios of governance and sometimes rare or endangered resources. [less ▲]

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