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See detailDiagnostic strategy for identifying avian pathogenic Escherichia coli based on four patterns of virulence genes
Schouler, C; Schaeffer, B; Brée, A et al

in Journal of Clinical Microbiology (2012), 50(5), 1673-1678

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See detailEstimating regional wheat yield from the shape of decreasing curves of green area index temporal profiles retrieved from MODIS data
Kouadio, Amani Louis ULg; Duveiller, Gregory; Djaby, Bakary ULg et al

in International Journal of Applied Earth Observation and Geoinformation (2012), 18

Earth observation data, owing to their synoptic, timely and repetitive coverage, have been recognized as a valuable tool for crop monitoring at different levels. At the field level, the close correlation ... [more ▼]

Earth observation data, owing to their synoptic, timely and repetitive coverage, have been recognized as a valuable tool for crop monitoring at different levels. At the field level, the close correlation between green leaf area (GLA) during maturation and grain yield in wheat revealed that the onset and rate of senescence appeared to be important factors for determining wheat grain yield. Our study sought to explore a simple approach for wheat yield forecasting at the regional level, based on metrics derived from the senescence phase of the green area index (GAI) retrieved from remote sensing data. This study took advantage of recent methodological improvements in which imagery with high revisit frequency but coarse spatial resolution can be exploited to derive crop-specific GAI time series by selecting pixels whose ground-projected instantaneous field of view is dominated by the target crop: winter wheat. A logistic function was used to characterize the GAI senescence phase and derive the metrics of this phase. Four regression-based models involving these metrics (i.e., the maximum GAI value, the senescence date and the thermal time taken to reach 50% of the green surface in the senescent phase) were related to official wheat yield data. The performances of such models at this regional scale showed that final yield could be estimated with an RMSE of 0.57 ton ha−1, representing about 7% as relative RMSE. Such an approach may be considered as a first yield estimate that could be performed in order to provide better integrated yield assessments in operational systems. [less ▲]

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See detailENMG (DES en Médecine Physique)
WANG, François-Charles ULg

Learning material (2012)

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See detailthe importance of late neuronal migration in the neonatal and following periods
Battisti, Oreste ULg; NYAMUGABO MUNYERE NKANA, Kindja ULg; MAZOIN, Nathalie ULg

in Developmental Medicine and Child Neurology. Supplement (2012), 54

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See detailA longitudinal study on the perinatal growth of brain, cerebellum and skeletal muscles in premature babies
Battisti, Oreste ULg; Withofs, Léon; Langhendries, Jean-Paul et al

in BMC Pregnancy and Childbirth (2012)

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See detailEffect of fruit age, pre-storage and seed fermentation durations on seed germination and seedling vigor in Lagenaria siceraria
Yao, Koffi Bertin; Konan, Amenan Jacky; Koffi, Kouamé Kévin et al

in Journal of Applied Biosciences (2012), (49), 3339-3351

Objectives : the study was conducted to determine the optimum age of the fruit at harvest and to evaluate the effect of pre-storage and fermentation on the seeds'agronomic performance of oleaginous ... [more ▼]

Objectives : the study was conducted to determine the optimum age of the fruit at harvest and to evaluate the effect of pre-storage and fermentation on the seeds'agronomic performance of oleaginous Lagenaria siceraria. Methodology and results : Fruit of the "round-fruited" and "blocky-fruited", two cultivars of the species, were harvested at 3 different ages (30, 40 and 50 days after anthesis (DAA)). These fruits were pre-stored during 0,30 and 60 days after harvest (DAH), and then their seeds were fermented for 0,5 and 10 days. Seed viability (germination percentage and germination speed index) and seedlings vigor (emergence percentage, emergence speed index, seedling shoot length and seedling dry weight) were significantly (P< 0.001) influenced by each of the three factors. Following the positive interaction of these factors, the best viability and the most vigorous seedlings were obtained with seeds from fruits tardily harvested (50 DAA), pre-stored for a long time (60 DAH) and longer fermented (10 days). The simultaneous variation of the fruit wet weight and the seed color, dry weight and moisture content with their viability and the seedlings vigor indicates that these four parameters can be used as indicators of both cultivars maturity. Conclusions and application of findings : The results suggest that in deaginous L siceraria, fruits must be harvested 50 DAA, pre-stored up to 60 DPA. Good agronomic quality seeds must have yellow-orange color and be fermented up to 10 days. [less ▲]

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See detailELISA : ECHELLE LIÉGEOISE DE L’INDICE DE SÉVÉRITÉ À L’ADMISSION
JOBE, Jérôme ULg; Ghuysen, Alexandre ULg; D'Orio, Vincenzo ULg

in Revue Médicale de Liège (2012), 67(12), 632-637

Les services d’urgence sont régulièrement confrontés au problème d’encombrement à l’admission par une demande qui dépasse l’offre de soins. Il est essentiel de réguler le flux d’entrée par la mise en ... [more ▼]

Les services d’urgence sont régulièrement confrontés au problème d’encombrement à l’admission par une demande qui dépasse l’offre de soins. Il est essentiel de réguler le flux d’entrée par la mise en place d’un dispositif de tri. Ce mécanisme s’affine depuis une quinzaine d’années. Nous proposons un algorithme de tri (ELISA ou Echelle Liégeoise de l’Indice de Sévérité à l’Admission) qui vise à définir l’état d’urgence selon 5 niveaux depuis la catégorie U1 (urgence absolue) à U5 (urgence relative). Ces niveaux sont associés à un délai de contact médical (immédiat à 120 minutes) et à un trajet de soin correspondant (salle de déchoquage, secteur B ou brancard, secteur A ou ambulatoire, salle d’attente) réunissant ainsi des impératifs de temps et de lieu de prise en charge optimaux. Notre algorithme de tri montre une excellente fiabilité par la comparaison du niveau initial de la catégorisation au devenir du patient (soins intensifs, hospitalisation, et sortie du service). [less ▲]

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See detailEinzigartigkeiten: Pluralrestriktionen im Wörterbuch
Münzberg, Franziska ULg

in Bär, Jochen; Müller, Marcus (Eds.) Geschichte der Sprache – Sprache der Geschichte. Probleme und Perspektiven der historischen Sprachwissenschaft des Deutschen (2012)

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See detailAn expanding Universe without dark matter and dark energy
Magain, Pierre ULg

E-print/Working paper (2012)

Assuming that observers located inside the Universe measure a time flow which is different from the time appearing in the Friedmann-Lemaıtre equation, and determining this time flow such that the Universe ... [more ▼]

Assuming that observers located inside the Universe measure a time flow which is different from the time appearing in the Friedmann-Lemaıtre equation, and determining this time flow such that the Universe always appears flat to these observers, we derive a simple cosmological model which allows to explain the velocity dispersions of galaxies in galaxy clusters without introducing dark matter. It also solves the horizon problem without recourse to inflation. Moreover, it explains the present acceleration of the expansion without any resort to dark energy and provides a good fit to the observations of distant supernovæ. Depending on the present value of the matter-energy density, we calculate an age of the Universe between 15.4 and 16.5 billion years, ignificantly larger than the 13.7 billion years of the standard CDM model. Our model has a slower expansion rate in the early epochs, thus leaving more time for the formation of structures such as stars and galaxies. [less ▲]

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See detailAbstract book - XIV European Congress of Ichthyology
Poncin, Pascal ULg; Parmentier, Eric ULg

Book published by ULg (2012)

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See detailChemical Composition and Antioxidant Activity of Essential Oil of Ocimum basilicum Leaves from the Northern Region of Algeria
Hadj Khelifa, L.; Brada, Moussa; Brahmi, F. et al

in Topclass Journal of Herbal Medicine (2012), 1(2), 53-58

Ocimum basilicum essential oil (Algerian species), which is extracted from dried leaves with an output of 1.98 ± 0.01%, is yellow pale. Its chemical composition has been investigated by GC/MS and GC/FID ... [more ▼]

Ocimum basilicum essential oil (Algerian species), which is extracted from dried leaves with an output of 1.98 ± 0.01%, is yellow pale. Its chemical composition has been investigated by GC/MS and GC/FID. Fourty compounds have been identified accounting for 97.4%. The major compounds were: Linalool (32.83%), linalyl acetate (16%), elemol (7.44%), geranyl acetate (6.18%), myrcene (6.12%), allo-ocimene (5.02%), α-terpineol (4.9%), (E)-β-ocimene (3.68%) and neryl acetate (3.45%). O. basilicum essential oil was screened for its in vitro antioxidant activity using DPPH assay. The results showed that the concentration of the essential oil needed to scavenge 50% of DPPH, was 83.54 mg/ml lower than that of vitamin E (22.0 mg/ml) and therefore acts as a natural antioxidant agent. [less ▲]

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See detailEtude de l’implication du microARN miR-146a dans
Halkein, Julie ULg

Doctoral thesis (2012)

La cardiomyopathie du péripartum (PPCM) est une maladie mortelle qui touche certaines femmes entre le dernier mois de la grossesse et jusqu’à 5 mois après l’accouchement. Ces femmes présentent des ... [more ▼]

La cardiomyopathie du péripartum (PPCM) est une maladie mortelle qui touche certaines femmes entre le dernier mois de la grossesse et jusqu’à 5 mois après l’accouchement. Ces femmes présentent des symptômes d’hypertension et un dysfonctionnemment du ventricule gauche. A la fois l’endothélium et les cardiomyocytes sont affectés dans le cœur des patientes atteintes de la PPCM et il a été récemment montré que le fragment de 16 kDa de la prolactine (PRL 16K) était un facteur majeur dans la pathophysiologie de la maladie. Dans notre laboratoire, nous travaillons depuis des années sur les mécanismes d’action de la PRL 16K. Nous nous intéressons également aux microARN (miARN), ces régulateurs de l’expression des gènes décrits pour être impliqués dans la plupart des processus physiologiques et pathologiques tels que l’angiogenèse ou les maladies cardiovasculaires. Ils sont également décrits depuis peu pour pouvoir être sécrétés par une cellule productrice et transférés à une cellule receveuse, via des microvésicules, afin d’y jouer un rôle. Au cours de ce travail, nous avons mis en évidence que la PRL 16K est capable d’induire l’expression de miR-146a au sein des cellules endothéliales via l’activation de NF-B et d’induire son transfert via des microvésicules appelées exosomes. Ces exosomes endothéliaux sont capable d’interagir avec les cardiomyocytes et le contenu en miR-146a y est transféré. Au sein des cellules endothéliales, miR-146a possède des propriétés anti-angiogènes. Il réprime la prolifération et favorise l’apoptose des cellules endothéliales. Parmi ses gènes cibles potentiels, nous validons NRAS via lequel miR-146a pourrait médier une partie de ses effets. Au sein des cardiomyocytes, nous avons mis en évidence un rôle de miR-146a dans la répression du métabolisme corrélé à une diminution de l’expression d’ErbB4. Nous avons ensuite montré le rôle central tenu par miR-146a dans un modèle murin de souris développant la PPCM. On retrouve dans le cœur de ces souris un niveau augmenté de miR-146a et un niveau diminué d’ErbB4 et de NRAS. De plus, l’inhibition de miR-146a dans ces souris PPCM, via l’injection d’oligonucléotides anti-sens, permet de restaurer le phénotype sain des souris PPCM. On observe une restauration de l’activité cardiaque ainsi qu’une normalisation des niveaux d’expression de miR-146a et de ses gènes cibles. Chez la femme présentant une PPCM, les niveaux cardiaques de miR-146a et d’ErbB4 sont également dérégulés. Ces résultats suggèrent que miR-146a tient un rôle central dans la pathophysiologie de la PPCM et permet d’expliquer la dualité d’action de la PRL 16K sur les cellules endothéliales et les cardiomyocytes. Enfin, les miARN extracellulaires présents dans le plasma constituent des biomarqueurs de choix pour le diagnostic d’un grand nombre de pathologies. Ainsi, nous avons mis en évidence un niveau d’expression plasmatique significativement plus élevé chez les patientes atteintes d’une PPCM comparé à celui de femmes saines ainsi que de patientes présentant également de l’insuffisance cardiaque dû à une cardiomyopathie dilatée. En conclusion, en plus d’être un facteur impliqué de façon centrale dans la pathophysiologie de la PPCM et constituant dès lors une cible thérapeutique intéressante, miR-146a permet un diagnostic spécifique de la maladie. [less ▲]

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See detailHierarchical clustering of brain activity during human nonrapid eye movement sleep.
Boly, Mélanie ULg; Perlbarg, V; Marrelec, G et al

in Proceedings of the National Academy of Sciences of the United States of America (2012)

Consciousness is reduced during nonrapid eye movement (NREM) sleep due to changes in brain function that are still poorly understood. Here, we tested the hypothesis that impaired consciousness during NREM ... [more ▼]

Consciousness is reduced during nonrapid eye movement (NREM) sleep due to changes in brain function that are still poorly understood. Here, we tested the hypothesis that impaired consciousness during NREM sleep is associated with an increased modularity of brain activity. Cerebral connectivity was quantified in resting-state functional magnetic resonance imaging times series acquired in 13 healthy volunteers during wakefulness and NREM sleep. The analysis revealed a modification of the hierarchical organization of large-scale networks into smaller independent modules during NREM sleep, independently from EEG markers of the slow oscillation. Such modifications in brain connectivity, possibly driven by sleep ultraslow oscillations, could hinder the brain's ability to integrate information and account for decreased consciousness during NREM sleep. [less ▲]

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See detailComment j'explore.... L'echographie thoracique: le nouveau stethoscope du pneumologue.
HEINEN, Vincent ULg; DUYSINX, Bernard ULg; CORHAY, Jean-Louis ULg et al

in Revue Médicale de Liège (2012), 67(10), 543-9

We now have access to a large library of publications validating transparietal thoracic echography in various clinical situations. Parietal lesions, including osteolysis, can be detected and biopsied ... [more ▼]

We now have access to a large library of publications validating transparietal thoracic echography in various clinical situations. Parietal lesions, including osteolysis, can be detected and biopsied during the thoracic ultrasound (TUS) examination. To evaluate the parietal extension of lung cancers, TUS has proved superior to tomodensitometry. Pleural effusions can be easily diagnosed and aspirated. Pneumothoraces can be detected using well defined lung artifacts with a high frequency probe. Pleural and peripheral lung nodules can be detected and biopsied with real time visualization; the procedure is safe and accurate. Lung consolidations with a pleural contact can be diagnosed; this is particularly useful for pregnant women. In conclusion, TUS is a precious diagnostic tool for chosen applications, and can help to guide interventional procedures. The portable devices are also very useful for bedridden patients or for out of hospital use. [less ▲]

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See detailCell proliferation in malignant melanoma: relationship with neoplastic progression.
PIERARD, Gérald ULg

in ISRN Dermatology (2012), 2012(art.828146), 1-12

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See detailTracking and treating malignant melanoma metastases.
PIERARD, Gérald ULg; HUMBERT, Philippe; QUATRESOOZ, Pascale ULg

in Dermatology Research and Practice (2012), 2012(art.173491), 1-2

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