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See detailDo Photobiont Switch and Cephalodia Emancipation Act as Evolutionary Drivers in the Lichen Symbiosis? A Case Study in the Pannariaceae (Peltigerales)
Magain, Nicolas ULg; Sérusiaux, Emmanuël ULg

in PLoS ONE (2014), 9(2), 89876

Lichen symbioses in the Pannariaceae associate an ascomycete and either cyanobacteria alone (usually Nostoc; bipartite thalli) or green algae and cyanobacteria (cyanobacteria being located in dedicated ... [more ▼]

Lichen symbioses in the Pannariaceae associate an ascomycete and either cyanobacteria alone (usually Nostoc; bipartite thalli) or green algae and cyanobacteria (cyanobacteria being located in dedicated structures called cephalodia; tripartite thalli) as photosynthetic partners (photobionts). In bipartite thalli, cyanobacteria can either be restricted to a well-delimited layer within the thallus (‘pannarioid’ thalli) or spread over the thallus that becomes gelatinous when wet (‘collematoid’ thalli). We studied the collematoid genera Kroswia and Physma and an undescribed tripartite species along with representatives of the pannarioid genera Fuscopannaria, Pannaria and Parmeliella. Molecular inferences from 4 loci for the fungus and 1 locus for the photobiont and statistical analyses within a phylogenetic framework support the following: (a) several switches from pannarioid to collematoid thalli occured and are correlated with photobiont switches; the collematoid genus Kroswia is nested within the pannarioid genus Fuscopannaria and the collematoid genus Physma is sister to the pannarioid Parmeliella mariana group; (b) Nostoc associated with collematoid thalli in the Pannariaceae are related to that of the Collemataceae (which contains only collematoid thalli), and never associated with pannarioid thalli; Nostoc associated with pannarioid thalli also associate in other families with similar morphology; (c) ancestors of several lineages in the Pannariaceae developed tripartite thalli, bipartite thalli probably resulting from cephalodia emancipation from tripartite thalli which eventually evolved and diverged, as suggested by the same Nostoc present in the collematoid genus Physma and in the cephalodia of a closely related tripartite species; Photobiont switches and cephalodia emancipation followed by divergence are thus suspected to act as evolutionary drivers in the family Pannariaceae. [less ▲]

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See detailGuías Europeas sobre manejo y evaluación de receptores y donantes renales
Pascual, Julio; Abramowicz, Daniel; Cochat, Pierre et al

in Nefrologia : Publicacion Oficial de la Sociedad Espanola Nefrologia (2014), 34(3), 293-301

El objetivo de esta guía de práctica clínica es ofrecer orientación para la evaluación tanto del donante como del receptor del trasplante de riñón y para el manejo del receptor durante el período ... [more ▼]

El objetivo de esta guía de práctica clínica es ofrecer orientación para la evaluación tanto del donante como del receptor del trasplante de riñón y para el manejo del receptor durante el período perioperatorio. Ha sido diseñada para informar y asistir en la toma de decisiones. En ningún caso pretende definir una norma asistencial ni su carácter debe concebirse como tal ni interpretarse como prescriptivo de un manejo exclusivo. La versión original de esta guía fue publicada en la revista Nephrology, Dialysis and Transplantation. Esta versión reducida pretende colaborar en la divulgación de esta guía en los países y las comunidades trasplantadoras hispanohablantes. [less ▲]

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See detailEvaluation of the Response of Shear Critical Walls Using a Three-Parameter Kinematic Theory
Mihaylov, Boyan ULg; Hannewald, Pia; Beyer, Katrin

in The 4th International fib Congress 2014 Mumbai - Proceedings (2014, February)

This paper discusses a newly developed three-parameter kinematic theory (3PKT) for shear critical walls with the help of four wall tests. The 3PKT is used to predict the pre- and post- peak response of ... [more ▼]

This paper discusses a newly developed three-parameter kinematic theory (3PKT) for shear critical walls with the help of four wall tests. The 3PKT is used to predict the pre- and post- peak response of the test units. Comparisons are performed with finite element (FE) models and plastic hinge models in combination with a shear degradation model. It is found that the latter underestimate the displacement capacity of the walls while the former do not predict well the post-peak response. The 3PKT with only three degrees of freedom captures the complete response of the walls provided that the size of the critical loading zone (CLZ) of the wall is well predicted. [less ▲]

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See detailThe role of protein modifications in senescence of freeze-dried Acetobacter senegalensis during storage
Shafiei, Rasoul ULg; Zarmehrkhorshid, Raziyeh ULg; Bentaib, Azeddine ULg et al

in Microbial Cell Factories (2014)

Background Loss of viability is one of the most important problems during starter culture production. Previous research has mostly focused on the production process of bacterial starters, but there are ... [more ▼]

Background Loss of viability is one of the most important problems during starter culture production. Previous research has mostly focused on the production process of bacterial starters, but there are few studies about cellular protein deterioration causing cell defectiveness during storage. In the present study, we investigated the influence of storage temperature (−21, 4, 35°C) on the cellular protein modifications which may contribute to the senescence of freeze-dried Acetobacter senegalensis. Results Heterogeneous populations composed of culturable cells, viable but non-culturable cells (VBNC) and dead cells were generated when freeze-dried cells were kept at −21 and 4°C for 12 months whereas higher storage temperature (35°C) mainly caused death of the cells. The analysis of stored cell proteome by 2D-DiGE demonstrated a modified pattern of protein profile for cell kept at 4 and 35°C due to the formation of protein spot trains and shift of Isoelectric point (pI). Quantification of carbonylated protein by ELISA showed that the cells stored at 4 and 35°C had higher carbonylated protein contents than fresh cells. 2D-DiGE followed by Western blotting also confirmed the carbonylation of cellular proteins involved in translation process and energy generation. The auto-fluorescent feature of cells kept at 35°C increased significantly which may be an indication of protein glycation during storage. In addition, the percentage of cellular unsaturated fatty acid and the solubility of cellular proteins decreased upon storage of cells at higher temperature suggesting that peroxidation of fatty acids and possibly protein lipidation and oxidation occurred. Conclusions High storage temperature induces some deteriorative reactions such as protein oxidation, lipidation and glycation which may cause further protein modifications like pI-shift, and protein insolubility. These modifications can partly account for the changes in cell viability. It can also be deduced that even moderate carbonylation of some critical cellular proteins (like ribosomal proteins) may lead to VBNC formation or death of freeze-dried bacteria. Moreover, it seems that other mechanisms of biomolecule deterioration preceding protein carbonylation lead to VBNC formation under very low storage temperature. [less ▲]

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See detailAnthropogenic effects on African Landscapes: Spatial Structure, Typologies, Ecological Impact
Vranken, Isabelle ULg

Poster (2014, February)

The problematique of anthropogenic disturbance on African landscapes is studied within the double framework of DPSIR (Drivers Pressures States Impact Response) and Pattern/Process Paradygm (Landscape ... [more ▼]

The problematique of anthropogenic disturbance on African landscapes is studied within the double framework of DPSIR (Drivers Pressures States Impact Response) and Pattern/Process Paradygm (Landscape Ecology). 20 landscae images from D.R. Congo, Ivory Coast and Benin were studied using indexes of spatial (compositional and configurational) heterogeneity and anthropogenic disturbance in order to highlight the relationship between spatial structure and disturbance intensity. The results show maximal heterogeneity at intermediate anthropogenic disturbances and fasten the triangular relationship between anthropogenic effect, biodiversity and spatial heterogeneity, that had been partially theoretised with the intermidiate disturbance and habitat heterogeneity hypotheses. [less ▲]

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See detailDevelopment of the ultrastructure of sonic muscles: a kind of neoteny?
Millot, Sandie; Parmentier, Eric ULg

in BMC Evolutionary Biology (2014), 14

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See detailContentieux européen
Wathelet, Melchior; Wildemeersch, Jonathan ULg

Book published by Larcier (2014)

L'ouvrage décrit l’architecture juridictionnelle de l’Union européenne et analyse en profondeur tous les types de recours qui peuvent être introduits devant les trois juridictions qui composent la Cour de ... [more ▼]

L'ouvrage décrit l’architecture juridictionnelle de l’Union européenne et analyse en profondeur tous les types de recours qui peuvent être introduits devant les trois juridictions qui composent la Cour de justice de l’Union européenne (la Cour de justice, le Tribunal et le Tribunal de la fonction publique), sans oublier le rôle important du juge national dans l’application quotidienne du droit de l’Union européenne. Si la première édition intégrait déjà les modifications apportées par le Traité de Lisbonne, sa récente entrée en vigueur laissait un nombre important de questions en suspens. Cette nouvelle édition permet de répondre à plusieurs d’entre elles (comme l’étendue de la nouvelle possibilité d’agir en annulation pour le particulier sur la base de l’article 263 du traité sur le fonctionnement de l’Union européenne par exemple). Elle intègre également les modifications apportées au statut de la Cour de justice et le nouveau règlement de procédure de la Cour entièrement refondu en octobre 2012. Le livre est construit sur une méthodologie originale en fondant leur propos et leur analyse sur la jurisprudence produite par les juridictions de la Cour de justice de l’Union européenne jusqu’au 31 janvier 2014. Ce sont ainsi près de 1900 décisions de jurisprudence qui sont commentées dans l’ouvrage (soit près de 600 supplémentaires par rapport à la première édition). Elles sont inventoriées minutieusement dans un index mis à disposition des praticiens. Les principaux textes de procédure propres aux juridictions européennes sont compilés dans un second volume. [less ▲]

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See detailCan a global dynamic vegetation model be used for both grassland and crop modeling at the local scale?
Minet, Julien ULg; Tychon, Bernard ULg; Jacquemin, Ingrid ULg et al

Poster (2014, February)

We report on the use of a dynamic vegetation model, CARAIB, within two modeling exercises in the framework of MACSUR. CARAIB is a physically-based, mechanistic model that calculates the carbon ... [more ▼]

We report on the use of a dynamic vegetation model, CARAIB, within two modeling exercises in the framework of MACSUR. CARAIB is a physically-based, mechanistic model that calculates the carbon assimilation of the vegetation as a function of the soil and climatic conditions. Within MACSUR, it was used in the model intercomparison exercises for grassland and crop modeling, in the LiveM 2.4 and CropM WP4 tasks, respectively. For grassland modeling, blind model runs at 11 locations were performed for various time ranges (few years). For crop modeling, a sensitivity analysis for building impact response surfaces (IRS) was performed, based on a bench of model runs at different levels of perturbation in the temperature and precipitation input data over 30 years. For grassland modeling, specific management functions accounting for the cutting or grazing of the grass were added to the model, in the framework of the MACSUR intercomparison. Initially developed for modeling the carbon dynamics of the natural vegetation, CARAIB was already adapted for crop modeling but further modifications regarding the management, i.e., yearly-dependent sowing dates, were introduced. For grassland modeling, simulation results will be further intercompared with other modeling groups, but preliminary results showed that the model could cope with the introduction of the grass cutting module. For crop modeling, building the IRS over 30 years permitted to assess the sensitivity of the model to temperature and precipitation changes. So far, the participation of CARAIB in the intercomparison exercises within MACSUR resulted in further improvements of the model by introducing new functionalities. [less ▲]

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See detailBayesian methods for predicting and modelling winter wheat biomass
Mansouri, Majdi ULg; Dumont, Benjamin ULg; Destain, Marie-France ULg

Poster (2014, February)

The objectives of this paper are threefold. The first objective is to propose to use an Improved Particle Filtering (IPF) based on minimizing Kullback-Leibler divergence for crop models' predictions. The ... [more ▼]

The objectives of this paper are threefold. The first objective is to propose to use an Improved Particle Filtering (IPF) based on minimizing Kullback-Leibler divergence for crop models' predictions. The performances of the proposed technique are compared with those of the conventional Particle Filtering (PF) for improving nonlinear crop model predictions. The main novelty of this task is to develop a Bayesian algorithm for nonlinear and non-Gaussian state and parameter estimation with better proposal distribution. The second objective is to investigate the effects of practical challenges on the performances of state estimation algorithms PF and IPF. Such practical challenges include (i) the effect of measurement noise on the estimation performances and (ii) the number of states and parameters to be estimated. The third objective is to use the state estimation techniques PF and IPF for updating prediction of nonlinear crop model in order to predict winter wheat biomass. PF and IPF are applied at a dynamic crop model with the aim to predict a state variable, namely the winter wheat biomass, and to estimate several model parameters. Furthermore, the effect of measurement noise (e.g., different signal-to-noise ratios) on the performances of PF and IPF is investigated. The results of the comparative studies show that the IPF provides a significant improvement over the PF because, unlike the PF which depends on the choice of sampling distribution used to estimate the posterior distribution, the IPF yields an optimum choice of the sampling distribution, which also accounts for the observed data. [less ▲]

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See detailSoil Seed Bank : a poorly know component of forest regeneration
Douh, Chauvelin ULg; Daïnou, Kasso ULg; Fernandez Pierna, Juan-Antonio et al

Poster (2014, February)

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See detailLe traitement médical conservateur des tendinopathies du genou
Kaux, Jean-François ULg; BAUVIR, Philippe ULg; Croisier, Jean-Louis ULg et al

in Ortho-Rhumato (2014), 12(1), 31-34

Les traitements «passifs» des tendinopathies sont généralement utilisés de manière empirique pour combattre la douleur mais ne modifient pas la structure histologique du tendon. Par contre, le travail ... [more ▼]

Les traitements «passifs» des tendinopathies sont généralement utilisés de manière empirique pour combattre la douleur mais ne modifient pas la structure histologique du tendon. Par contre, le travail excentrique a pour but de contrecarrer une théorie étiopathogénique proposant une insuffisance de résistance du tendon exposé à des charges externes qui peuvent progressivement entrainer des lésions. Les résultats cliniques suite à cette prise en charge montrent souvent une évolution favorable des douleurs. Les ondes de choc extra-corporelles demeurent une option thérapeutique non-invasives et présentent peu de complications. De plus, elles sont employées avec succès pour traiter des tendinopathies chroniques rebelles aux traitements conservateurs classiques. Le plasma riche en plaquettes (PRP) est obtenu par centrifugation de sang autologue afin d’obtenir une grande concentration plaquettaire dépendant de la technique employée. Malgré la preuve de l’efficacité du PRP sur la régénération tissulaire en laboratoire, il existe actuellement peu de preuves cliniques tangibles concernant le traitement des tendinopathies chroniques. Enfin, d’autres nouvelles options thérapeutiques (patches de dérivés nitrés, infiltrations de polidocanol, d’acide hyaluronique et de cellules souches) sont également abordées. [less ▲]

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See detailCoûts de soins de malades diabétiques hospitalisés en court séjour à Lubumbashi : Etude descriptive transversale
Mundongo Tshamba, Henri; Kaj Malonga, Françoise; Ditend, Grévisse et al

in Diabetes Research & Clinical Practice (2014), 103(Supplement 1), 32

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See detailL'image du mois. L'effet chatterjee
BORN, B; IOVINO, Alessandra ULg; NYSSEN, Astrid ULg et al

in Revue Médicale de Liège (2014)

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See detailCROSSROADS - magazine sonore des musiques noires US
Sacré, Robert ULg

Diverse speeche and writing (2014)

CROSSROADS : émission radio hebdomadaire diffusée sur EQUINOXE FM 100.1 (on line via www.equinoxefm.be) : tous les mercredis de 18 à 20h : contenu : blues,R&B,Soul, gospel, Zydeco, jazz

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See detailA stochastic framework for subspace identification of a strongly nonlinear aerospace structure
Noël, Jean-Philippe ULg; Schoukens, Johan; Kerschen, Gaëtan ULg

in Proceedings of the International Modal Analysis Conference (IMAC) XXXII (2014, February)

The present study exploits the maximum likelihood identification framework for deriving statistically-optimal models of nonlinear mechanical systems. The identification problem is formulated in the ... [more ▼]

The present study exploits the maximum likelihood identification framework for deriving statistically-optimal models of nonlinear mechanical systems. The identification problem is formulated in the frequency domain, and model parameters are calculated by minimising a weighted least-squares cost function. Initial values of the model parameters are obtained by means of a nonlinear subspace algorithm. The complete identification methodology is first demonstrated on a Duffing oscillator, prior to being applied to a full-scale aerospace structure. [less ▲]

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See detailParameter identification of the STICS crop model, using an accelerated formal MCMC approach
Dumont, Benjamin ULg; Leemans, Vincent ULg; Mansouri, Majdi ULg et al

in Environmental Modelling & Software (2014), 52

This study presents a Bayesian approach for the parameters’ identification of the STICS crop model based on the recently developed Differential Evolution Adaptive Metropolis (DREAM) algorithm. The ... [more ▼]

This study presents a Bayesian approach for the parameters’ identification of the STICS crop model based on the recently developed Differential Evolution Adaptive Metropolis (DREAM) algorithm. The posterior distributions of nine specific crop parameters of the STICS model were sampled with the aim to improve the growth simulations of a winter wheat (Triticum aestivum L.) culture. The results obtained with the DREAM algorithm were initially compared to those obtained with a Nelder-Mead Simplex algorithm embedded within the OptimiSTICS package. Then, three types of likelihood functions implemented within the DREAM algorithm were compared, namely the standard least square, the weighted least square, and a transformed likelihood function that makes explicit use of the coefficient of variation (CV). The results showed that the proposed CV likelihood function allowed taking into account both noise on measurements and heteroscedasticity which are regularly encountered in crop modelling [less ▲]

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See detailEffective stress method to be used in beam finite elements to take local instabilities into account
Franssen, Jean-Marc ULg; Cowez, Baptiste; Gernay, Thomas ULg

in Fire Safety Science 11 (2014, February)

In the fire situation, Bernoulli beam finite elements are the workhorse used in numerical calculation model for simulating the behaviour of the structure. Such finite elements treat all sections as class ... [more ▼]

In the fire situation, Bernoulli beam finite elements are the workhorse used in numerical calculation model for simulating the behaviour of the structure. Such finite elements treat all sections as class 1 (stocky) sections whatever the slenderness of the plates that make the section, allowing the development of a full plastic stress distribution in the section which leads to complete plastic redistribution along the members in the structure. This type of element is thus not adapted for modeling structures that contain slender sections of class 2, 3 or 4. This document presents a new approach to take into account local instabilities in slender sections using beam finite elements. The new approach is based on an effective constitutive law of steel. The effective law is not symmetrical with respect to tension and compression because, in tension, the stress-strain relationship is not modified whereas, in compression, the stress-strain relationship is modified. [less ▲]

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See detailLes plateformes MOOCs. Menaces et opportunités pour l’enseignement universitaire
Jacqmin, Julien ULg; belleflamme, paul

in Regards Economiques (2014), 110

Cela fait plusieurs mois que les médias se font abondamment l’écho du développement des MOOCs. Derrière cet acronyme un peu barbare (qui se prononce ‘Moûk’) se cachent de nouvelles méthodes pour dispenser ... [more ▼]

Cela fait plusieurs mois que les médias se font abondamment l’écho du développement des MOOCs. Derrière cet acronyme un peu barbare (qui se prononce ‘Moûk’) se cachent de nouvelles méthodes pour dispenser l’enseignement supérieur. MOOC signifie en effet «Massive Open Online Course» ou, en français, «cours en ligne ouvert et massif» : ‘en ligne’ parce que tout l’enseignement est suivi sur Internet, ‘ouvert’ parce que n’importe qui peut y accéder et "massif" parce que rien n’empêche que des milliers d’étudiants suivent le même cours au même moment. Ces cours sont offerts par des plateformes Internet qui apparaissent comme de nouveaux acteurs dans le paysage de l’enseignement supérieur, acteurs dont le fonctionnement et les impacts potentiels se doivent d’être analysés. [less ▲]

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See detailEffect of postremission therapy before reduced-intensity conditioning allogeneic transplantation for acute myeloid leukemia in first complete remission
Warlick, Erica; Paulson, Kristjan; Brazauskas, Ruta et al

in Biology of Blood & Marrow Transplantation (2014), 20(2), 202-208

The impact of pre transplant (HCT) cytarabine consolidation therapy on post HCT outcomes has yet to be evaluated after reduced intensity or non-myeloablative conditioning. We analyzed 604 adults with ... [more ▼]

The impact of pre transplant (HCT) cytarabine consolidation therapy on post HCT outcomes has yet to be evaluated after reduced intensity or non-myeloablative conditioning. We analyzed 604 adults with acute myeloid leukemia (AML) in first complete remission (CR1) reported to the CIBMTR who received a RIC or NMA HCT from an HLA-identical sibling, HLA-matched unrelated donor (URD), or umbilical cord blood (UCB) donor in 2000-2010. We compared transplant outcomes based on exposure to cytarabine post remission consolidation. Three year survival rates were 36% (29-43%, 95% CI) in the no consolidation arm and 42% (37-47%, 95% CI) in the cytarabine consolidation arm (p=0.16). Disease free survival was 34% (27-41%, 95% CI) and 41% (35-46%, 95% CI) (p=0.15), respectively. Three year cumulative incidences of relapse were 37% (30-44%, 95% CI) and 38% (33-43%, 95% CI), respectively (p=0.80). Multivariate regression confirmed no effect of consolidation on relapse, DFS and survival. Prior to RIC/NMA HCT, these data suggest pre-HCT consolidation cytarabine does not significantly alter outcomes and support prompt transition to transplant as soon as morphologic CR1 is attained. If HCT is delayed while identifying a donor, our data suggest that consolidation does not increase transplant TRM and is reasonable if required. [less ▲]

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