Publications ORBi OA     Results 6981-7000 of 39676.   345 346 347 348 349 350 351 352 353 354 355   Compte rendu de G. BUTAUD, Les compagnies de routiers en France (1357-1393)Masson, Christophe in Moyen Age (Le) (2013), CXIXDetailed reference viewed: 47 (2 ULg) Seagrass production: linking individual, community and ecosystem carbon fluxesSantos, R; Silva, J; Olivé, I et alConference (2013)Detailed reference viewed: 17 (1 ULg) Flavor origin of R-parityMorisi, S.; Peinado, E.; Vicente, Avelino in Journal of Physics : G Nuclear & Particle Physics (2013), 40Detailed reference viewed: 5 (0 ULg) Tree-level lepton universality violation in the presence of sterile neutrinos: impact for $R_K$ and $R_\pi$Abada, A.; Das, D.; Teixeira, A. M. et alin Journal of High Energy Physics [=JHEP] (2013), 1302Detailed reference viewed: 9 (2 ULg) Compte rendu de J. FLORI, L’idéologie du glaive. Préhistoire de la chevalerieMasson, Christophe in Moyen Age (Le) (2013), CXIXDetailed reference viewed: 25 (3 ULg) Sterile neutrinos and $R_K$Vicente, Avelino in Journal of Physics: Conference Series (2013), 447Detailed reference viewed: 11 (1 ULg) Bilinear R-parity violation with flavor symmetryBazzocchi, F.; Morisi, S.; Peinado, E. et alin Journal of High Energy Physics [=JHEP] (2013), 1301Detailed reference viewed: 8 (0 ULg) Analysis of $\alpha_s$ from the realization of quark-hadron dualityCourtoy, Aurore ; Liuti, Simonettain World Scientific (2013)Detailed reference viewed: 11 (1 ULg) Comment concilier medecine factuelle et medecine personnalisee?Scheen, André in Revue medicale suisse (2013), 9(395), 1499-500Detailed reference viewed: 15 (1 ULg) La metformine: une molecule antidiabetique dotee de proprietes anti-cancereuses.BECK, Emmanuel ; Scheen, André in Revue medicale de Liege (2013), 68(9), 444-9Numerous epidemiological cohort and case-control studies showed that type 2 diabetes is a risk factor for cancer and that metformin therapy is associated with a significant reduction in the incidence of ... [more ▼]Numerous epidemiological cohort and case-control studies showed that type 2 diabetes is a risk factor for cancer and that metformin therapy is associated with a significant reduction in the incidence of cancer and cancer-related death when compared to other glucose-lowering agents. Such beneficial effect is observed whatever the type of cancer, but seems to be more prominent in case of gastrointestinal and breast cancers. In general, the protective effect was more evident in observational cohort studies (however, more exposed to bias due to confounding factors) than in case-control studies. However, the results of the rather rare controlled clinical trials available are not conclusive, but none of them was performed with the objective to specifically assess cancer risk. Several meta-analyses recently confirmed that metformin therapy reduces the incidence of cancers (including colorectal cancer, hepatocarcinoma, breast cancer) and cancer-related mortality. Metformin may exert its anti-cancer activity by a direct effect (insulin) and an indirect effect (AMPK and mTOR). Considering all promising clinical information in patients with type 2 diabetes, further clinical trials are currently ongoing with the aim of assessing the role of metformin in oncology, especially as adjuvant in breast cancer therapy. [less ▲]Detailed reference viewed: 38 (2 ULg) Utilisation de la metformine chez le patient diabetique cardiaque: balance benefices-risques.Scheen, André ; Paquot, Nicolas in Revue medicale suisse (2013), 9(395), 1527-33Metformin is unanimously considered as the first-line glucose-lowering agent in type 2 diabetes. Theoretically, however, it cannot be prescribed in a large proportion of patients because of the presence ... [more ▼]Metformin is unanimously considered as the first-line glucose-lowering agent in type 2 diabetes. Theoretically, however, it cannot be prescribed in a large proportion of patients because of the presence of numerous contraindications corresponding to situations that may increase the risk of lactic acidosis. Recent data suggest that type 2 diabetes patients who are considered as being "at risk" because of the presence of cardiac disease still take benefit from metformin therapy, with a reduction of morbidity and mortality compared with other glucose-lowering agents. The present review analyzes the benefit-risk balance of metformin therapy in special populations, namely patients with stable coronary artery disease, acute coronary syndrome or myocardial infarction, or congestive heart failure. [less ▲]Detailed reference viewed: 13 (0 ULg) Immunohistochemical patterns in the interfollicular Caucasian scalps. Influence of age-, gender- and alopecia.Franchimont, Claudine ; Loussouarn, Genevière; Panhard, Ségolène et alin BioMed Research International (2013), 2013(769489), Detailed reference viewed: 14 (3 ULg) Neonatal seizures or convulsionsBattisti, Oreste ; DUBRU, Jean-Marie Learning material (2013)diaporama et video des convulsions néonatalesDetailed reference viewed: 75 (6 ULg) Utilisation de la voie laparoscopie extra-péritonéale pour la réalisation des lymphadénectomies aortiques chez des patientes obèsesFerron, G.; Martinez, A.; DE CUYPERE, Marjolein et alin e-mémoires de l'Académie Nationale de Chirurgie (2013), 12(3), 013Detailed reference viewed: 19 (3 ULg) Mobility of Cu and Co in soils from metalliferous ecosystems: results from a lysimeter study in Lubumbashi (Katanga)Kaya Muyumba, Donato ; Liénard, Amandine ; Pourret, Olivier et alPoster (2013)Detailed reference viewed: 39 (10 ULg) L’enzyme11β-HSD1 : une nouvelle cible potentielle pour le traitement du diabète de type 2 et des maladies métaboliques liées à l’obésitéSCHEEN, André ; BECK, Emmanuel in Diabète et Obésité (2013), 8The 11 beta-hydroxysteroid dehydrogenase type 1 (11βHSD1) enzyme promotes the local conversion from cortisone to cortisol, especially in the adipose tissue and the liver. It may play a role in the ... [more ▼]The 11 beta-hydroxysteroid dehydrogenase type 1 (11βHSD1) enzyme promotes the local conversion from cortisone to cortisol, especially in the adipose tissue and the liver. It may play a role in the pathophysiology of abdominal obesity and the metabolic syndrome, both showing some similarities with the Cushing syndrome. Synthetic selective inhibitors of 11βHSD1 are currently in development with encouraging preliminary results that remain, however, to be further improved. Selective inhibitors of 11βHSD1 may represent an innovative approach in the pharmacological management of obesity, metabolic syndrome and type 2 diabetes. [less ▲]Detailed reference viewed: 32 (2 ULg) An updated and quality controlled surface mass balance dataset for AntarcticaFavier, Vincent; Agosta, Cécile ; Parouty, Soazig et alin Cryosphere (The) (2013), 7We present an updated and quality controlled surface mass balance (SMB) database for the Antarctic ice sheet. We retrieved a total of 5284 SMB data documented with important meta-data, to which a filter ... [more ▼]We present an updated and quality controlled surface mass balance (SMB) database for the Antarctic ice sheet. We retrieved a total of 5284 SMB data documented with important meta-data, to which a filter was applied to discard data with limited spatial and temporal representativeness, too small measurement accuracy, or lack of quality control. A total of 3438 reliable data was obtained, which is about four times more than by applying the same data filtering process to previously available databases. New important data with high spatial resolution are now available over long traverses, and at low elevation in some areas. However, the quality control led to a considerable reduction in the spatial density of data in several regions, particularly over West Antarctica. Over interior plateaus, where the SMB is low, the spatial density of mea- surements remained high. This quality controlled dataset was compared to results from ERA-Interim reanalysis to assess model representativeness over Antarctica, and also to identify large areas where data gaps impede model validation. Except for very few areas (e.g. Adelie Land), the elevation range between 200 m and 1000 m a.s.l. is not correctly sampled in the field, and measurements do not allow a thorough validation of models in regions with complex topography, where the highest scattering of SMB values is reported. Clearly, increasing the spatial density of field measurements at low elevations, in the Antarctic Peninsula and in West Antarctica remains a scientific priority. [less ▲]Detailed reference viewed: 46 (5 ULg) Transport of Snow by the Wind: A Comparison Between Observations in Adélie Land, Antarctica, and Simulations Made with the Regional Climate Model MARGallée, Hubert; Trouvillez, Alexandre; Agosta, Cécile et alin Boundary-Layer Meteorology (2013), 146(1), 133--147For the first time a simulation of blowing snow events was validated in detail using one-month long observations (January 2010) made in Adélie Land, Antarctica. A regional climate model featuring a ... [more ▼]For the first time a simulation of blowing snow events was validated in detail using one-month long observations (January 2010) made in Adélie Land, Antarctica. A regional climate model featuring a coupled atmosphere/blowing snow/snowpack model is forced laterally by meteorological re-analyses. The vertical grid spacing was 2 m from 2 to 20 m above the surface and the horizontal grid spacing was 5 km. The simulation was validated by comparing the occurrence of blowing snow events and other meteorological parameters at two automatic weather stations. The Nash test allowed us to compute effi- ciencies of the simulation. The regional climate model simulated the observed wind speed with a positive efficiency (0.69). Wind speeds higher than 12 m s−1 were underestimated. Positive efficiency of the simulated wind speed was a prerequisite for validating the blowing snow model. Temperatures were simulated with a slightly negative efficiency (−0.16) due to overestimation of the amplitude of the diurnal cycle during one week, probably because the cloud cover was underestimated at that location during the period concerned. Snowfall events were correctly simulated by our model, as confirmed by field reports. Because observations suggested that our instrument (an acoustic sounder) tends to overestimate the blowing snow flux, data were not sufficiently accurate to allow the complete validation of snow drift val- ues. However, the simulation of blowing snow occurrence was in good agreement with the observations made during the first 20 days of January 2010, despite the fact that the blowing snow flux may be underestimated by the regional climate model during pure blowing snow events. We found that blowing snow occurs in Adélie Land only when the 30-min wind speed value at 2 m a.g.l. is >10 m s−1. The validation for the last 10 days of January 2010 was less satisfactory because of complications introduced by surface melting and refreezing. [less ▲]Detailed reference viewed: 21 (5 ULg) Approvisionnement alimentaire de la ville de Bukavu : flux en provenance de l'intérieur du Sud-Kivu, du Rwanda et du Nord-KivuVwima Ngezirabona, Stany ; Lebailly, Philippe Poster (2013)Ce travail caractérise les flux principaux d’approvisionnements alimentaires de la ville de Bukavu en provenance de l’intérieur de la province du Sud-Kivu, du Nord-Kivu et du Rwanda issus du pointage des ... [more ▼]Ce travail caractérise les flux principaux d’approvisionnements alimentaires de la ville de Bukavu en provenance de l’intérieur de la province du Sud-Kivu, du Nord-Kivu et du Rwanda issus du pointage des flux des produits alimentaires. [less ▲]Detailed reference viewed: 22 (7 ULg) Etude de modes de production de charbon de bois sur l'axe Lubumbashi-KasengaNge Okwe, A.; Ngoy Shutcha, M.; Nkulu Mwine Fyama, J. et alPoster (2013)Detailed reference viewed: 69 (19 ULg)