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See detailCompte rendu de G. BUTAUD, Les compagnies de routiers en France (1357-1393)
Masson, Christophe ULg

in Moyen Age (Le) (2013), CXIX

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See detailSeagrass production: linking individual, community and ecosystem carbon fluxes
Santos, R; Silva, J; Olivé, I et al

Conference (2013)

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See detailFlavor origin of R-parity
Morisi, S.; Peinado, E.; Vicente, Avelino ULg

in Journal of Physics : G Nuclear & Particle Physics (2013), 40

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See detailTree-level lepton universality violation in the presence of sterile neutrinos: impact for $R_K$ and $R_\pi$
Abada, A.; Das, D.; Teixeira, A. M. et al

in Journal of High Energy Physics [=JHEP] (2013), 1302

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See detailCompte rendu de J. FLORI, L’idéologie du glaive. Préhistoire de la chevalerie
Masson, Christophe ULg

in Moyen Age (Le) (2013), CXIX

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See detailSterile neutrinos and $R_K$
Vicente, Avelino ULg

in Journal of Physics: Conference Series (2013), 447

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See detailBilinear R-parity violation with flavor symmetry
Bazzocchi, F.; Morisi, S.; Peinado, E. et al

in Journal of High Energy Physics [=JHEP] (2013), 1301

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See detailAnalysis of $\alpha_s$ from the realization of quark-hadron duality
Courtoy, Aurore ULg; Liuti, Simonetta

in World Scientific (2013)

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See detailComment concilier medecine factuelle et medecine personnalisee?
Scheen, André ULg

in Revue medicale suisse (2013), 9(395), 1499-500

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See detailLa metformine: une molecule antidiabetique dotee de proprietes anti-cancereuses.
BECK, Emmanuel ULg; Scheen, André ULg

in Revue medicale de Liege (2013), 68(9), 444-9

Numerous epidemiological cohort and case-control studies showed that type 2 diabetes is a risk factor for cancer and that metformin therapy is associated with a significant reduction in the incidence of ... [more ▼]

Numerous epidemiological cohort and case-control studies showed that type 2 diabetes is a risk factor for cancer and that metformin therapy is associated with a significant reduction in the incidence of cancer and cancer-related death when compared to other glucose-lowering agents. Such beneficial effect is observed whatever the type of cancer, but seems to be more prominent in case of gastrointestinal and breast cancers. In general, the protective effect was more evident in observational cohort studies (however, more exposed to bias due to confounding factors) than in case-control studies. However, the results of the rather rare controlled clinical trials available are not conclusive, but none of them was performed with the objective to specifically assess cancer risk. Several meta-analyses recently confirmed that metformin therapy reduces the incidence of cancers (including colorectal cancer, hepatocarcinoma, breast cancer) and cancer-related mortality. Metformin may exert its anti-cancer activity by a direct effect (insulin) and an indirect effect (AMPK and mTOR). Considering all promising clinical information in patients with type 2 diabetes, further clinical trials are currently ongoing with the aim of assessing the role of metformin in oncology, especially as adjuvant in breast cancer therapy. [less ▲]

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See detailUtilisation de la metformine chez le patient diabetique cardiaque: balance benefices-risques.
Scheen, André ULg; Paquot, Nicolas ULg

in Revue medicale suisse (2013), 9(395), 1527-33

Metformin is unanimously considered as the first-line glucose-lowering agent in type 2 diabetes. Theoretically, however, it cannot be prescribed in a large proportion of patients because of the presence ... [more ▼]

Metformin is unanimously considered as the first-line glucose-lowering agent in type 2 diabetes. Theoretically, however, it cannot be prescribed in a large proportion of patients because of the presence of numerous contraindications corresponding to situations that may increase the risk of lactic acidosis. Recent data suggest that type 2 diabetes patients who are considered as being "at risk" because of the presence of cardiac disease still take benefit from metformin therapy, with a reduction of morbidity and mortality compared with other glucose-lowering agents. The present review analyzes the benefit-risk balance of metformin therapy in special populations, namely patients with stable coronary artery disease, acute coronary syndrome or myocardial infarction, or congestive heart failure. [less ▲]

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See detailImmunohistochemical patterns in the interfollicular Caucasian scalps. Influence of age-, gender- and alopecia.
Franchimont, Claudine ULg; Loussouarn, Genevière; Panhard, Ségolène et al

in BioMed Research International (2013), 2013(769489),

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See detailNeonatal seizures or convulsions
Battisti, Oreste ULg; DUBRU, Jean-Marie ULg

Learning material (2013)

diaporama et video des convulsions néonatales

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See detailUtilisation de la voie laparoscopie extra-péritonéale pour la réalisation des lymphadénectomies aortiques chez des patientes obèses
Ferron, G.; Martinez, A.; DE CUYPERE, Marjolein ULg et al

in e-mémoires de l'Académie Nationale de Chirurgie (2013), 12(3), 013

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See detailL’enzyme11β-HSD1 : une nouvelle cible potentielle pour le traitement du diabète de type 2 et des maladies métaboliques liées à l’obésité
SCHEEN, André ULg; BECK, Emmanuel ULg

in Diabète et Obésité (2013), 8

The 11 beta-hydroxysteroid dehydrogenase type 1 (11βHSD1) enzyme promotes the local conversion from cortisone to cortisol, especially in the adipose tissue and the liver. It may play a role in the ... [more ▼]

The 11 beta-hydroxysteroid dehydrogenase type 1 (11βHSD1) enzyme promotes the local conversion from cortisone to cortisol, especially in the adipose tissue and the liver. It may play a role in the pathophysiology of abdominal obesity and the metabolic syndrome, both showing some similarities with the Cushing syndrome. Synthetic selective inhibitors of 11βHSD1 are currently in development with encouraging preliminary results that remain, however, to be further improved. Selective inhibitors of 11βHSD1 may represent an innovative approach in the pharmacological management of obesity, metabolic syndrome and type 2 diabetes. [less ▲]

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See detailAn updated and quality controlled surface mass balance dataset for Antarctica
Favier, Vincent; Agosta, Cécile ULg; Parouty, Soazig et al

in Cryosphere (The) (2013), 7

We present an updated and quality controlled surface mass balance (SMB) database for the Antarctic ice sheet. We retrieved a total of 5284 SMB data documented with important meta-data, to which a filter ... [more ▼]

We present an updated and quality controlled surface mass balance (SMB) database for the Antarctic ice sheet. We retrieved a total of 5284 SMB data documented with important meta-data, to which a filter was applied to discard data with limited spatial and temporal representativeness, too small measurement accuracy, or lack of quality control. A total of 3438 reliable data was obtained, which is about four times more than by applying the same data filtering process to previously available databases. New important data with high spatial resolution are now available over long traverses, and at low elevation in some areas. However, the quality control led to a considerable reduction in the spatial density of data in several regions, particularly over West Antarctica. Over interior plateaus, where the SMB is low, the spatial density of mea- surements remained high. This quality controlled dataset was compared to results from ERA-Interim reanalysis to assess model representativeness over Antarctica, and also to identify large areas where data gaps impede model validation. Except for very few areas (e.g. Adelie Land), the elevation range between 200 m and 1000 m a.s.l. is not correctly sampled in the field, and measurements do not allow a thorough validation of models in regions with complex topography, where the highest scattering of SMB values is reported. Clearly, increasing the spatial density of field measurements at low elevations, in the Antarctic Peninsula and in West Antarctica remains a scientific priority. [less ▲]

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See detailTransport of Snow by the Wind: A Comparison Between Observations in Adélie Land, Antarctica, and Simulations Made with the Regional Climate Model MAR
Gallée, Hubert; Trouvillez, Alexandre; Agosta, Cécile ULg et al

in Boundary-Layer Meteorology (2013), 146(1), 133--147

For the first time a simulation of blowing snow events was validated in detail using one-month long observations (January 2010) made in Adélie Land, Antarctica. A regional climate model featuring a ... [more ▼]

For the first time a simulation of blowing snow events was validated in detail using one-month long observations (January 2010) made in Adélie Land, Antarctica. A regional climate model featuring a coupled atmosphere/blowing snow/snowpack model is forced laterally by meteorological re-analyses. The vertical grid spacing was 2 m from 2 to 20 m above the surface and the horizontal grid spacing was 5 km. The simulation was validated by comparing the occurrence of blowing snow events and other meteorological parameters at two automatic weather stations. The Nash test allowed us to compute effi- ciencies of the simulation. The regional climate model simulated the observed wind speed with a positive efficiency (0.69). Wind speeds higher than 12 m s−1 were underestimated. Positive efficiency of the simulated wind speed was a prerequisite for validating the blowing snow model. Temperatures were simulated with a slightly negative efficiency (−0.16) due to overestimation of the amplitude of the diurnal cycle during one week, probably because the cloud cover was underestimated at that location during the period concerned. Snowfall events were correctly simulated by our model, as confirmed by field reports. Because observations suggested that our instrument (an acoustic sounder) tends to overestimate the blowing snow flux, data were not sufficiently accurate to allow the complete validation of snow drift val- ues. However, the simulation of blowing snow occurrence was in good agreement with the observations made during the first 20 days of January 2010, despite the fact that the blowing snow flux may be underestimated by the regional climate model during pure blowing snow events. We found that blowing snow occurs in Adélie Land only when the 30-min wind speed value at 2 m a.g.l. is >10 m s−1. The validation for the last 10 days of January 2010 was less satisfactory because of complications introduced by surface melting and refreezing. [less ▲]

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See detailApprovisionnement alimentaire de la ville de Bukavu : flux en provenance de l'intérieur du Sud-Kivu, du Rwanda et du Nord-Kivu
Vwima Ngezirabona, Stany ULg; Lebailly, Philippe ULg

Poster (2013)

Ce travail caractérise les flux principaux d’approvisionnements alimentaires de la ville de Bukavu en provenance de l’intérieur de la province du Sud-Kivu, du Nord-Kivu et du Rwanda issus du pointage des ... [more ▼]

Ce travail caractérise les flux principaux d’approvisionnements alimentaires de la ville de Bukavu en provenance de l’intérieur de la province du Sud-Kivu, du Nord-Kivu et du Rwanda issus du pointage des flux des produits alimentaires. [less ▲]

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See detailEtude de modes de production de charbon de bois sur l'axe Lubumbashi-Kasenga
Nge Okwe, A.; Ngoy Shutcha, M.; Nkulu Mwine Fyama, J. et al

Poster (2013)

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