Publications ORBi OA
Bookmark and Share    
Full Text
Peer Reviewed
See detailPlanktonic and whole system metabolism in a nutrient rich estuary (the Scheldt estuary)
Gazeau, Frédéric; Gattuso, Jean-Pierre; Middelburg, Jack J. et al

in Estuaries (2005), 28(6), 868-883

Planktonic gross primary production (GPP), community respiration (CR), and nitrification (NIT) were measured monthly in the Scheldt estuary by the oxygen incubation method in 2003. No significant ... [more ▼]

Planktonic gross primary production (GPP), community respiration (CR), and nitrification (NIT) were measured monthly in the Scheldt estuary by the oxygen incubation method in 2003. No significant evolution of planktonic GPP was observed since the 1990s with high rates in the freshwater area (salinity 0; 97 6 65 mmol C m22 d21) decreasing seaward (22–37 mmol C m22 d21). A significant decrease of NIT was observed with regard to previous investigations although this process still represents up to 20% of total organic matter production in the inner estuary. Planktonic CR was highest in the inner estuary and seemed to be mainly controlled by external organic matter inputs. Planktonic net community production was negative most of the time in the estuary with values ranging from 2300 to 165 mmol C m22 d21. Whole estuary net ecosystem production (NEP) was investigated on an annual scale using the results mentioned above and published benthic metabolic rates. A NEP of 239 6 8 mmol C m22 d21 was estimated, which confirms the strong heterotrophic status of this highly nutrified estuary. NEP rates were computed from June to December 2003 to compare with results derived from the Land-Ocean Interaction in the Coastal Zone budgeting procedure applied to dissolved inorganic phosphorus and carbon (DIP and DIC). DIP budgets failed to provide realistic estimates in the inner estuary where abiotic processes account for more than 50% of the nonconservative DIP flux. DIC budgets predicted a much lower NEP than in situ incubations (2109 6 31 versus 242 6 9 mmol C m22 d21) although, as each approach is associated with several critical assumptions, the source of this discrepancy remains unclear. [less ▲]

Detailed reference viewed: 15 (3 ULg)
Full Text
Peer Reviewed
See detailPlasticity of cultured mesenchymal stem cells: switch from nestin-positive to excitable neuron-like phenotype.
Wislet-Gendebien, Sabine ULg; Hans, Grégory ULg; Leprince, Pierre ULg et al

in Stem Cells (2005), 23(3), 392-402

Bone marrow mesenchymal stem cells (MSCs) can differentiate into several types of mesenchymal cells, including osteocytes, chondrocytes, and adipocytes, but, under appropriate experimental conditions, can ... [more ▼]

Bone marrow mesenchymal stem cells (MSCs) can differentiate into several types of mesenchymal cells, including osteocytes, chondrocytes, and adipocytes, but, under appropriate experimental conditions, can also differentiate into nonmesenchymal cells--for instance, neural cells. These observations have raised interest in the possible use of MSCs in cell therapy strategies for various neurological disorders. In the study reported here, we addressed the question of in vitro differentiation of MSCs into functional neurons. First, we demonstrate that when they are co-cultured with cerebellar granule neurons, adult MSCs can express neuronal markers. Two factors are needed for the emergence of neuronal differentiation of the MSCs: the first one is nestin expression by MSCs (nestin is a marker for the responsive character of MSCs to extrinsic signals), and the second one is a direct cell-cell interaction between neural cells and MSCs that allows the integration of these extrinsic signals. Three different approaches suggest that neural phenotypes arise from MSCs by a differentiation rather than a cell fusion process, although this last phenomenon can also coexist. The expression of several genes--including sox, pax, notch, delta, frizzled, and erbB--was analyzed by quantitative reverse transcription polymerase chain reaction (RT-PCR) in order to further characterize the nestin-positive phenotype compared to the nestin-negative one. An overexpression of sox2, sox10, pax6, fzd, erbB2, and erbB4 is found in nestin-positive MSCs. Finally, electrophysiological analyses demonstrate that MSC-derived neuron-like cells can fire single-action potentials and respond to several neurotransmitters such as GABA, glycine, and glutamate. We conclude that nestin-positive MSCs can differentiate in vitro into excitable neuron-like cells. [less ▲]

Detailed reference viewed: 59 (4 ULg)
Full Text
See detailA Review of the hard pomeron in soft diffraction
Cudell, Jean-René ULg; Lengyel, Alexander; Martynov, Evgenij et al

in Nuclear Physics A (2005), 755

We review the evidence for the presence of a hard singularity in soft forward amplitudes, and give an estimate of its trajectory and couplings.

Detailed reference viewed: 52 (11 ULg)
Full Text
Peer Reviewed
See detailControls of the surface water partial pressure of CO2 in the North Sea
Thomas, H.; Bozec, Y.; de Baar, Hein J. W. et al

in Biogeosciences (2005), 2(4), 323-334

The seasonal variability of the partial pressure of CO2 (pCO2) has been investigated in the North Sea, a northwest European shelf sea. Based on a seasonal and high spatial resolution data set the main ... [more ▼]

The seasonal variability of the partial pressure of CO2 (pCO2) has been investigated in the North Sea, a northwest European shelf sea. Based on a seasonal and high spatial resolution data set the main controlling factors – biological processes and temperature - have been identified and quantified. In the central and northern parts being a CO2- sink all year round, the biological control dominates the temperature control. In the southern part, the temperature control dominates the biological control at an annual scale, since the shallow water column prevents stronger net-CO2 removal from the surface layer due to the absence of seasonal stratification. The consequence is a reversal of the CO2 seato- air flux during the spring bloom period, the only time, when CO2 is taken up from the atmosphere in the southern region. Net community production in the mixed layer has been estimated to 4mol Cm−2 yr−1 with higher values (4.3 mol Cm−2 yr−1) in the northern part and lower values in the southern part (2.6 mol Cm−2 yr−1). [less ▲]

Detailed reference viewed: 143 (1 ULg)
Full Text
See detailDevelopment of edumetrical indices for the analysis of the spectral quality of higher education standardized tests
Gilles, Jean-Luc ULg

in 11th Biennal Conference of the European Association for Research on Learning and Instruction - Multiple Perspectives on Effective Learning Enviroments - Abstracts (2005)

Detailed reference viewed: 20 (3 ULg)
Full Text
Peer Reviewed
See detailGeochemistry of cumulates from the Bjerkreim-Sokndal layered intrusion (S. Norway). Part I. Constraints from major elements on the mechanism of cumulate formation and on the jotunite liquid line of descent
Duchesne, Jean-Clair ULg; Charlier, Bernard ULg

in Lithos (2005), 83(3-4), 229-254

Whole-rock major element compositions are investigated in 99 cumulates from the Proterozoic Bjerkreim-Sokndal layered intrusion (Rogaland Anorthosite Province, SW Norway), which results from the ... [more ▼]

Whole-rock major element compositions are investigated in 99 cumulates from the Proterozoic Bjerkreim-Sokndal layered intrusion (Rogaland Anorthosite Province, SW Norway), which results from the crystallization of a jotunite (Fe-Ti-P-rich hypersthene monzodiorite) parental magma. The scattering of cumulate compositions covers three types of cumulates: (1) ilmenite-leuconorite with plagioclase, ilmenite and Ca-poor pyroxene as cumulus minerals, (2) magnetite-leuconorite with the same minerals plus magnetite, and (3) gabbronorite made up of plagioclase, Ca-poor and Ca-rich pyroxenes, ilmenite, Ti-magnetite and apatite. Each type of cumulate displays a linear trend in variation diagrams. One pole of the linear trends is represented by plagioclase, and the other by a mixture of the mafic minerals in constant proportion. The mafic minerals were not sorted during cumulate formation though they display large density differences. This suggests that crystal settling did not operate during cumulate formation, and that in situ crystallization with variable nucleation rate for plagioclase was the dominant formation mechanism. The trapped liquid fraction of the cumulate plays a negligible role for the cumulate major element composition. Each linear trend is a locus for the cotectic composition of the cumulates. This property permits reconstruction by graphical mass balance calculation of the first two stages of the liquid line of descent, starting from a primitive jotunite, the Tjorn, parental magma. Another type of cumulate, called jotunite cumulate and defined by the mineral association from the Transition Zone of the intrusion, has to be subtracted to simulate the most evolved part of the liquid line of descent. The proposed model demonstrates that average cumulate compositions represent cotectic compositions when the number of samples is large (> 40). The model, however, does not account for the K2O evolution, suggesting that the system was open to contamination by roof melts. The liquid line of descent corresponding to the Bjerkreim-Sokndal cumulates differs slightly from that obtained for jotunitic dykes in that the most Ti-, P- and Fe-rich melts (evolved jotunite) are lacking. The constant composition of the mafic poles during intervals where cryptic layering is conspicuous is explained by a compositional balance between the Fe-Ti oxide minerals. which decrease in Fe content in favour of Ti. and the pyroxenes which increase in Fe. (c) 2005 Elsevier B.V. All rights reserved. [less ▲]

Detailed reference viewed: 39 (0 ULg)
Full Text
Peer Reviewed
See detailL'audition disciplinaire du fonctionnaire
Donnay, Luc ULg

in Administration Publique [=AP] : Revue du Droit Public et des Sciences Administratives (2005), (1), 61-75

Detailed reference viewed: 180 (11 ULg)
Full Text
Peer Reviewed
See detailRéseaux et souvenirs littéraires : le cas d'André Fontainas
Dozo, Björn-Olav ULg; de Marneffe, Daphné

in Textyles : Revue des Lettres Belges de Langue Française (2005), 26-27

Detailed reference viewed: 68 (14 ULg)
Full Text
Peer Reviewed
See detailQualitative assessment of the purity of multi-walled carbon nanotube samples using krypton adsorption
Gommes, Cédric ULg; Noville, Francis ULg; Bossuot, Christophe et al

in Studies in Surface Science and Catalysis (2005), 160

Krypton is a subcritical vapour at the nitrogen boiling temperature. As such, its adsorption on crystalline surfaces leads to condensation steps, typical of type VI isotherms according to IUPAC, while its ... [more ▼]

Krypton is a subcritical vapour at the nitrogen boiling temperature. As such, its adsorption on crystalline surfaces leads to condensation steps, typical of type VI isotherms according to IUPAC, while its adsorption on rough surfaces is BET-like. Based on this property of krypton adsorption at 77 K, a methodology is proposed to determine the purity of carbon nanotubes samples. The method is tested on model samples obtained by mixing mechanically purified multi-walled carbon nanotubes with various amounts of the same catalyst as used for their synthesis. [less ▲]

Detailed reference viewed: 48 (1 ULg)
Full Text
Peer Reviewed
See detailAnaemia management strategies: optimising treatment using epoetin beta (NeoRecormon).
Glaspy, John; Beguin, Yves ULg

in Oncology (2005), 69 Suppl 2

Anaemia has a detrimental impact on quality of life and it is important that this condition is recognised and treated in patients with cancer. Epoetin beta is an effective and well-tolerated treatment of ... [more ▼]

Anaemia has a detrimental impact on quality of life and it is important that this condition is recognised and treated in patients with cancer. Epoetin beta is an effective and well-tolerated treatment of anaemia in patients with a wide range of solid and haematological malignancies. A study in patients with lymphoid malignancies confirms that epoetin beta is equally effective at the same overall weekly dose (30,000 IU weekly) when given once-weekly or three-times weekly. This once-weekly regimen has also proved effective in patients with solid tumours. Once-weekly treatment is more convenient for the patient, potentially improving compliance and is associated with reduced hospital administration costs. The majority of patients with cancer will respond to epoetin therapy with an increase in haemoglobin levels. However, it is of value to identify those patients who are likely to respond, so that cost-effectiveness can be improved. Despite much research into potential predictive factors, follow-up studies are required and clinical judgement remains key to managing the anaemia of cancer. In addition, studies suggest that intravenous iron supplementation can improve response to epoetin therapy in patients with functional iron deficiency. Epoetin beta offers an effective, safe and convenient therapy for the management of anaemia in patients with cancer. Ongoing studies are expected to lead to a greater understanding of the optimal use of epoetins in cancer-related anaemia. [less ▲]

Detailed reference viewed: 30 (0 ULg)
Full Text
Peer Reviewed
See detailImmunotherapie du cancer par minigreffe de cellules souches hematopoietiques.
Willems, Evelyne ULg; Baron, Frédéric ULg; Vanstraelen, Gaëtan et al

in Revue Médicale Suisse (2005), 1(30), 1973-7

Allogeneic hematopoietic stem cell transplantation (HSCT) is used for the treatment of selected haematological malignancies. Its curative potential is based on two different mechanisms, i.e. the ... [more ▼]

Allogeneic hematopoietic stem cell transplantation (HSCT) is used for the treatment of selected haematological malignancies. Its curative potential is based on two different mechanisms, i.e. the conditioning regimen and the graft-versus-host immunologic reactions. However, because of its toxicity, it is restricted to younger and fitter patients. These observations led several groups to set up new (less toxic) transplant protocols. These transplants are called nonmyeloablative HSCT or minitransplants. These are feasible with a relatively low transplant-related mortality even in patients up to 70 years. In addition, strong anti-tumor responses are observed in several haematological malignancies. [less ▲]

Detailed reference viewed: 99 (5 ULg)
Full Text
Peer Reviewed
See detailPrimary amyloidosis (AL) as a cause of nephrotic syndrome.
Bataille, Yoann ULg; Bovy, Christophe ULg; Lancellotti, Patrizio ULg et al

in Acta Clinica Belgica (2005), 60(2), 94-7

AL amyloidosis is a rare systemic disease resulting from tissue accumulation of amyloid fibrils derived from monoclonal immunoglobulin light chains. It can disrupt the tissue architecture and consequently ... [more ▼]

AL amyloidosis is a rare systemic disease resulting from tissue accumulation of amyloid fibrils derived from monoclonal immunoglobulin light chains. It can disrupt the tissue architecture and consequently cause organ dysfunction. The prognosis is poor with a median survival of 13 months in untreated patients. By illustrating the case of a patient whose AL amyloidosis was detected after presenting a nephrotic syndrome, the characteristics of the disease are reviewed as well as diagnostic criteria and current available therapeutics. [less ▲]

Detailed reference viewed: 55 (8 ULg)
Full Text
Peer Reviewed
See detailInfluence of exogenous oestrogen or (anti-) androgen administration on soluble transferrin receptor in human plasma.
T'Sjoen, Guy; Beguin, Yves ULg; Feyen, Els et al

in Journal of Endocrinology (2005), 186(1), 61-7

The objective of this investigation was to study the effects of sex steroids on levels of haemoglobin (Hb) and haematocrit (Hct) and to analyse whether these effects can be related to levels of the ... [more ▼]

The objective of this investigation was to study the effects of sex steroids on levels of haemoglobin (Hb) and haematocrit (Hct) and to analyse whether these effects can be related to levels of the soluble transferrin receptor (sTfR), a marker of erythropoietic activity. Nineteen male-to-female transsexuals were randomly assigned to either oral ethinyl oestradiol (EE) (n=12) or transdermal 17beta-oestradiol (E2) (n=7); both treatments included the anti-androgen cyproterone acetate (CA). Six male-to-female transsexuals were treated with CA only. Fifteen female-to-male transsexuals were treated with i.m. testosterone esters. The Hct, and levels of Hb, IGF-I, GH and sTfR were measured before and after 4 months of hormone administration. Androgen administration significantly increased the sTfR concentration by 31.5% (P=0.008) and increased levels of Hct, Hb and IGF-I. Both regimens of CA with oral EE and transdermal E2 reduced plasma testosterone similarly to castrate values and decreased Hb and Hct. The CA+oral EE combination induced a decrease in sTfR of 19.0% (P=0.002) which was not the case with CA+transdermal E2 (P=0.27). This cannot be explained by the profound decline in plasma testosterone which was similar with both regimens, but this difference could be related to the different effects of the two regimens on plasma IGF-I. This assumption is supported by the positive correlation that was found to exist between plasma sTfR and IGF-I after the interventions (P<0.05). [less ▲]

Detailed reference viewed: 19 (0 ULg)
Full Text
Peer Reviewed
See detailLes neuroblastomes de l'enfant. A propos de 23 cas.
Piette, Catherine ULg; Dresse, Marie-Françoise ULg; Forget, Patricia ULg et al

in Revue Médicale de Liège (2005), 60(3), 173-80

In this retrospective study, we analyse epidemiology, clinical symptoms and therapeutic results in a group of 23 children with neuroblastoma. Half of them were less than 2 years of age; in 19 of 23, the ... [more ▼]

In this retrospective study, we analyse epidemiology, clinical symptoms and therapeutic results in a group of 23 children with neuroblastoma. Half of them were less than 2 years of age; in 19 of 23, the primitive tumour was abdominal; 35% of them were initially metastatic. The overall survival was 83% at 5 years and the event free survival, 75% at 5 years. Pronostic factors are age, extension of the disease at diagnosis, biologic parameters and genetic study of the neuroblast cells (amplification of N-myc oncogen). Our study shows the deleterious effect of bone lesions. [less ▲]

Detailed reference viewed: 168 (4 ULg)
Full Text
Peer Reviewed
See detailEfficacy of recombinant human erythropoietin therapy started one month after autologous peripheral blood stem cell transplantation.
Vanstraelen, Gaetan; Baron, Frédéric ULg; Frere, Pascale ULg et al

in Haematologica (2005), 90(9), 1269-70

On day 30 after autologous peripheral blood stem cell transplantation (PBSCT), 20 patients were randomized to receive either erythropoietin at a dose of 500 U/kg/week s.c. (Epo group) or no treatment ... [more ▼]

On day 30 after autologous peripheral blood stem cell transplantation (PBSCT), 20 patients were randomized to receive either erythropoietin at a dose of 500 U/kg/week s.c. (Epo group) or no treatment (control group). After 3 weeks, hemoglobin (p<0.0001) and serum transferrin receptor (p<0.0001) concentrations were higher in the Epo group. Hb response (+2 g/dL) was achieved in 100% vs 28% (p<0.0001) and Hb correction (> or =13 g/dL) in 70% vs 10% (p=0.0238) of the patients, respectively. This is the first randomized study showing an efficacy of erythropoietin therapy on Hb levels after autologous PBSCT. [less ▲]

Detailed reference viewed: 48 (3 ULg)
Full Text
Peer Reviewed
See detailAnalyse climatique de la région de Gouré, Niger oriental : récentes modifications et impacts environnementaux
Ozer, Pierre ULg; Bodart, Catherine ULg; Tychon, Bernard ULg

in Cybergeo : Revue Européenne de Géographie = Cybergeo - European Journal of Geography (2005)

Since the late 1960s, the Sahel is affected by a dramatic drought. This article analyses climatic variations recorded in the Gouré area, eastern Niger, between 1936 and 2003. It appears that the drought ... [more ▼]

Since the late 1960s, the Sahel is affected by a dramatic drought. This article analyses climatic variations recorded in the Gouré area, eastern Niger, between 1936 and 2003. It appears that the drought ended in the late 1980s. However, the rainfall increase did not lead to an extension of the length of the rainy season. The study of the wind shows that correct data were recorded during the two first years of the station of Gouré (1984 and 1985). Afterwards, wind speed was entached by errors and did not report since 1997. The situation is alarming as we know that neighbouring stations meet the same problems and that no synoptic station currently reports wind values in eastern Niger. However, based on wind speed and deflation data recorded in 1984, a threshold wind speed of 7 m/s was determined in Gouré. Finally, from measurements of horizontal visibility reduced by mineral dust, our results suggest that air quality is reduced because of the high frequency of wind erosion. The confrontation of our results with recent environmental studies in that region show that the end of the drought did not lead to any landscape improvement. Increasing human pressure tends to be the main driving factor of land degradation. [less ▲]

Detailed reference viewed: 190 (48 ULg)
Full Text
Peer Reviewed
See detailJean Le Blond, premier traducteur français de l'Utopie
Dozo, Björn-Olav ULg

in Lettres Romanes (2005), LIX(3-4), 187-210

Detailed reference viewed: 53 (7 ULg)
Full Text
Peer Reviewed
See detailConserving local goats breeds and traditional pastoralism in Southern France
Bertaglia, Marco; Mormont, Marc ULg; Trometter, Michel

in Agricoltura Mediterranea (2005), 135(2), 77-94

Extensive livestock productions is historically linked to local, traditional breeds. Both these production systems and traditional breeds have markedly declined or even disappeared in some areas, as a ... [more ▼]

Extensive livestock productions is historically linked to local, traditional breeds. Both these production systems and traditional breeds have markedly declined or even disappeared in some areas, as a result of global trends toward intensification, specialisation and abandonment of marginal areas. More recently, interest in the preservation of livestock biodiversity has been revived. Concern over the livelihood of marginal rural areas and landscape management accompanies the political debate over rare breeds. Parallel to institutional activity, and in many cases as forerunners, social actors have undertaken action to avoid both breed extinction and the loss of pastoralist traditions. In this paper, we present the findings of a qualitative survey of local goat husbandry in Southern France. Non-directive interviews of extension experts and breeders of two local goat breeds, the Rove and the Provençal, revealed a strong link between the breeders’ perception of local breeds/pastoralism and their broader worldview. Most breeders are “back-to-the-landers”. Their choice to raise local breeds in the pastoralist way is linked to a vision of society as a whole. Their account is interpreted as the will to resist to mainstream discourse and practice of rural development in marginal areas. [less ▲]

Detailed reference viewed: 64 (14 ULg)
Full Text
Peer Reviewed
See detailDe quelques aspects de droit pénal social et de procédure pénale susceptibles d'être rencontrés par le juge social ou le juge répressif
Michiels, Olivier ULg; Derre, Sylvie

in Revue Belge de Sécurité Sociale (2005), 2

On pourrait penser que les incidences du droit pénal social se limitent aux procédures menées devant les juridictions répressives. S’il est vrai que son terrain de prédilection demeure la sanction de ... [more ▼]

On pourrait penser que les incidences du droit pénal social se limitent aux procédures menées devant les juridictions répressives. S’il est vrai que son terrain de prédilection demeure la sanction de comportements pénalement répréhensibles, le droit pénal social présente toutefois différentes facettes. Ainsi, si la responsabilité pénale des personnes morales et les condamnations d’office prévues par la loi du 27 juin 1969 concernant la sécurité sociale des travailleurs relèvent des préoccupations immédiates du juge répressif, la notion de subordination, les amendes administratives ou encore l’autorité de chose jugée du pénal sur le civil, pour ne citer que ces trois exemples, procèdent de la pratique habituelle du juge civil. L'article a, dès lors, pour but de mettre en lumière plusieurs sujets qui, de près ou de loin, se ramifient au domaine répressif tout en ayant comme objectif d’appréhender la doctrine, la jurisprudence et la législation actuelles. [less ▲]

Detailed reference viewed: 287 (14 ULg)