Publications ORBi OA
Bookmark and Share    
Full Text
See detailRetour sur les romans du 11 septembre
Delville, Michel ULiege

Article for general public (2010)

Detailed reference viewed: 68 (9 ULiège)
Full Text
Peer Reviewed
See detailFuselage structure optimization
Grihon, Stéphane; Samuelides, Manuel; Merval, Arnaud et al

in Kesseler, Ernst; Guenov, Martin (Eds.) Advances in Collaborative Civil Aeronautical Multidisciplinary Optimization (2010)

Detailed reference viewed: 39 (0 ULiège)
Full Text
See detailDylan Thomas en chansons
Delville, Michel ULiege

Article for general public (2010)

Detailed reference viewed: 27 (1 ULiège)
Full Text
See detailAntonio Lobo Antunes
Delville, Michel ULiege

in Culture, le magazine culturel de l'Université de Liège (2010)

Detailed reference viewed: 276 (6 ULiège)
Full Text
Peer Reviewed
See detailQuality of mixing in a stirred bioreactor used for animal cells culture: heterogeneities in a lab scale bioreactor and evolution of mixing time with scale up
Collignon, Marie-Laure ULiege; Dossin, Denis; Delafosse, Angélique ULiege et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2010), 14

Animal cells are industrially cultivated inside stirred bioreactors to produce proteinic compounds. Due to the use of mild agitation conditions in order to limit mechanical constraints, the homogeneity of ... [more ▼]

Animal cells are industrially cultivated inside stirred bioreactors to produce proteinic compounds. Due to the use of mild agitation conditions in order to limit mechanical constraints, the homogeneity of the culture medium can be far from perfect. This study has therefore two objectives. 1) the global characterization of the mixing via the mixing time 2) the local description of concentration fields. The mixing time is measured by conductimetry inside 20 L, 80 L, 600L tanks. The Grenville correlation is adjusted on these experimental measurements to improve the prediction of the mixing time during the scale-up of the process. The concentration fields are visualized by the Planar Laser Induced Fluorescence (P.L.I.F) technique in the 20 L tank. This part of the study is focused on the time evolution of the maximum value of the tracer concentration inside measurement planes and of the numerical distribution of theses concentration fields. [less ▲]

Detailed reference viewed: 119 (31 ULiège)
Full Text
See detailManifestes!
Delville, Michel ULiege

Article for general public (2010)

Detailed reference viewed: 36 (1 ULiège)
Full Text
Peer Reviewed
See detailImproved modelling of helium and tritium production for spallation targets
Leray, S.; Boudard, A.; Cugnon, Joseph ULiege et al

in Nuclear Instruments & Methods in Physics Research. Section B, Beam Interactions with Materials and Atoms (2010), 268(6), 581-586

Detailed reference viewed: 18 (0 ULiège)
Full Text
Peer Reviewed
See detailRaccontare Zeus. Poesia e cultura di corte ad Alessandria, a partire dall’Inno I di Callimaco
Caneva, Stefano ULiege

in Pallas : Revue d'Etudes Antiques (2010), 83

Detailed reference viewed: 55 (2 ULiège)
Full Text
Peer Reviewed
See detailCanguilhem, Erwin Straus et la phénoménologie : la question de l'organisame vivant
Gérard, Marie ULiege

in Bulletin D'Analyse (2010), 6(2), 118-145

Detailed reference viewed: 34 (2 ULiège)
Full Text
Peer Reviewed
See detailThymic self-antigens for the design of a negative/tolerogenic self-vaccination against type 1 diabetes.
Geenen, Vincent ULiege; Mottet, Marie ULiege; Dardenne, Olivier ULiege et al

in Current Opinion in Pharmacology (2010), 10

Before being able to react against infectious non-self antigens, the immune system has to be educated in the recognition and tolerance of neuroendocrine proteins and this critical process takes place only ... [more ▼]

Before being able to react against infectious non-self antigens, the immune system has to be educated in the recognition and tolerance of neuroendocrine proteins and this critical process takes place only in the thymus. The development of the autoimmune diabetogenic response results from a thymus dysfunction in programming central self-tolerance to pancreatic insulin-secreting islet β cells, leading to the breakdown of immune homeostasis with an enrichment of islet β-cell reactive effector T cells and a deficiency of β-cell specific natural regulatory T cells (nTregs) in the peripheral T-lymphocyte repertoire. Insulin-like growth factor 2 (IGF-2) is the dominant member of the insulin family expressed during fetal life by the thymic epithelium under the control of the autoimmune regulator (AIRE) gene/protein. The very low degree of insulin gene transcription in normal murine and human thymus explains why the insulin protein is poorly tolerogenic as evidenced in many studies, including the failure of all clinical trials that have attempted immune tolerance to islet β cells via various methods of insulin administration. Based on the close homology and cross-tolerance between insulin, the primary T1D autoantigen, and IGF-2, the dominant self-antigen of the insulin family, a novel type of vaccination, so-called “negative/tolerogenic self-vaccination”, is currently being developed for prevention and cure of T1D. If this approach were found to be effective for reprogramming immunological tolerance in T1D, it could pave the way for the design of other self-vaccines against autoimmune endocrine diseases, as well as other organ-specific autoimmune diseases. [less ▲]

Detailed reference viewed: 64 (19 ULiège)
Full Text
Peer Reviewed
See detailDermatophytoses : actualités épidémiologiques et diagnostiques
Mignon, Bernard ULiege

in Pratique Vet (2010), 45

Detailed reference viewed: 82 (16 ULiège)
Full Text
Peer Reviewed
See detailMagnetocaloric effect in nano- and polycrystalline manganites La0.5Ca0.5MnO3
Pekala, Marek; Drozd, Vadym; Fagnard, Jean-François ULiege et al

in Journal of Alloys & Compounds (2010), 507

Structure, magnetic and magnetocaloric properties of poly- and nanocrystalline La0.5Ca0.5MnO3 manganites prepared by the citrate sol–gel method are studied in a broad temperature range. The Arrott plots ... [more ▼]

Structure, magnetic and magnetocaloric properties of poly- and nanocrystalline La0.5Ca0.5MnO3 manganites prepared by the citrate sol–gel method are studied in a broad temperature range. The Arrott plots show that the phase transition is of the second order. The cooling efficiency of 93–97 J/kg is found for the poly- and nanocrystalline samples. The relatively weaker magnetocaloric effect in nanocrystalline La0.5Ca0.5MnO3 is spread over temperature range almost three times broader than for the polycrystalline one. Charge ordering effects decay in manganites with grain sizes below 150 nm. [less ▲]

Detailed reference viewed: 150 (17 ULiège)
Full Text
See detailBoolean Models and Methods in Mathematics, Computer Science, and Engineering
Crama, Yves ULiege; Hammer, Peter L.

Book published by Cambridge University Press (2010)

This collection of papers proposes in-depth presentations of a variety of advanced topics related to Boolean functions and expressions. The chapters are written by some of the most prominent experts in ... [more ▼]

This collection of papers proposes in-depth presentations of a variety of advanced topics related to Boolean functions and expressions. The chapters are written by some of the most prominent experts in their respective fields, and cover topics ranging from algebra and propositional logic to learning theory, cryptography, computational complexity, electrical engineering, and reliability theory. Beyond the diversity of the questions raised and investigated in different chapters, a remarkable feature of the collection is the common thread created by the fundamental language, concepts, models and tools provided by Boolean theory. Many readers will certainly be surprised to discover countless links between seemingly remote topics discussed in various chapters of the book. They will hopefully be able to draw on such connections to further their understanding of their own scientific discipline and to explore new avenues for research. [less ▲]

Detailed reference viewed: 130 (14 ULiège)
Full Text
Peer Reviewed
See detailThe protein Nod2: an innate receptor more complex than previously assumed.
Lecat, Aurore ULiege; Piette, Jacques ULiege; Legrand-Poels, Sylvie ULiege

in Biochemical Pharmacology (2010), 80(12), 2021-31

For almost 10 years, Nod2 has been known as a cytosolic innate receptor able to sense peptidoglycan from Gram-positive and -negative bacteria and to trigger RIP2- and NF-kappaB-mediated pro-inflammatory ... [more ▼]

For almost 10 years, Nod2 has been known as a cytosolic innate receptor able to sense peptidoglycan from Gram-positive and -negative bacteria and to trigger RIP2- and NF-kappaB-mediated pro-inflammatory and antibacterial response. Mutations in the gene encoding Nod2 in humans have been associated with Crohn's disease (CD). Mechanisms by which Nod2 variants can lead to CD development are still under investigation. The most admitted hypothesis suggests that the impaired function of Nod2 variants in intestinal epithelial and phagocytic cells results in deficiencies in epithelial-barrier function which subsequently lead to increased bacterial invasion and inflammation at intestinal sites. Very recent results have just reinforced this hypothesis by demonstrating that Nod2 wild-type (unlike Nod2 variants) could mediate autophagy, allowing an efficient bacterial clearance and adaptative immune response. Other recent data have attributed new roles to Nod2. Indeed, Nod2 has been shown to activate antiviral innate immune responses involving IRF3-dependent IFN-beta production after viral ssRNA recognition through a RIP2-independent mechanism requiring the mitochondrial adaptor protein MAVS. Recently, Nod2 has been also shown to be exquisitely tuned to detect mycobacterial infections and mount a protective immunity against these pathogens. [less ▲]

Detailed reference viewed: 36 (5 ULiège)
Full Text
Peer Reviewed
See detailDe rol van de aardrijkskunde in de koloniale wetenschappen.
Vandersmissen, Jan ULiege

in Bulletin des Séances de l’Académie Royale des Sciences d’Outre-Mer = Mededelingen der Zittingen van de Koninklijke Academie voor Overzeese Wetenschappen (2010), 56(2), 105-120

In this lecture various aspects of geography as an “imperial science” in the 19th century are discussed, especially with regard to the Belgian colonial history of that period. We follow geography’s ... [more ▼]

In this lecture various aspects of geography as an “imperial science” in the 19th century are discussed, especially with regard to the Belgian colonial history of that period. We follow geography’s development from von Humboldt’s time, when the exploration of the world still had to lead towards a better comprehension of all physical phenomena in “Cosmos”, up to the first decades of Belgian presence in Congo, when geography was on the forefront of a highly utilitarian and materialistic exploration. This transition can be seen in all sorts of institutions. While science academies in the 18th and the beginning of the 19th century still gave instructions to travelers in order to systematize exploration as an instrument of science, specialized geographical societies in the second half of the 19th century developed a discourse of economic expansionism that expressed itself in exploratory missions with a political and economical agenda. The Belgian geographical movement was a world where colonial ideas could grow, and where the geographical societies of Antwerp and Brussels became propaganda instruments in the service of King Leopold’s African enterprise. Although geography marched ahead in the process of knowledge transfer, the encounter with reality on the field ended in a confrontation with geography’s limitations. Other scientific disciplines such as medicine, botany and geology got more and more involved in the colonial enterprise. [less ▲]

Detailed reference viewed: 93 (6 ULiège)
Full Text
See detailOptimization on manifolds : methods and applications
Absil, P.-A.; Mahony, R.; Sepulchre, Rodolphe ULiege

in Recent Advances in Optimization and its Applications in Engineering (2010)

Summary. This paper provides an introduction to the topic of optimization on manifolds. The approach taken uses the language of differential geometry, however, we choose to emphasise the intuition of the ... [more ▼]

Summary. This paper provides an introduction to the topic of optimization on manifolds. The approach taken uses the language of differential geometry, however, we choose to emphasise the intuition of the concepts and the structures that are important in generating practical numerical algorithms rather than the technical details of the formulation. There are a number of algorithms that can be applied to solve such problems and we discuss the steepest descent and Newton’s method in some detail as well as referencing the more important of the other approaches. There are a wide range of potential applications that we are aware of, and we briefly discuss these applications, as well as explaining one or two in more detail. [less ▲]

Detailed reference viewed: 85 (2 ULiège)
Full Text
Peer Reviewed
See detailPractice guidelines on the use of erythropoiesis-stimulating agents in the treatment of chemotherapy-induced anemia
Dirix, L.; Awada, A.; Bron, D. et al

in Belgian Journal of Medical Oncology [=BJMO] (2010), 4

On July 1st 2009, a panel of experts met with the goal to provide a joint medical opinion on the use of erythropoiesis-stimulating agents (ESAs) in chemotherapy-induced anemia (CIA), as well as a joint ... [more ▼]

On July 1st 2009, a panel of experts met with the goal to provide a joint medical opinion on the use of erythropoiesis-stimulating agents (ESAs) in chemotherapy-induced anemia (CIA), as well as a joint proposal for revised reimbursement criteria in Belgium. The goal is to provide a clear and workable guidance on the use of ESAs in their registrered indication : chemotherapy induced anemia in cancer patients. An overview of participating experts can be found in Table 1. [less ▲]

Detailed reference viewed: 90 (2 ULiège)
Full Text
Peer Reviewed
See detailObservance thérapeutique en hématologie : le cas particulier de la leucémie myéloïde chronique
Roufosse, Renaud ULiege; Beguin, Yves ULiege

in Revue Médicale de Liège (2010), 65

Therapeutic adhesion is essential because it modulates the efficiency of treatment, the occurrence of side effects and the socioeconomic costs possibly associated with it. In haematology, in the ... [more ▼]

Therapeutic adhesion is essential because it modulates the efficiency of treatment, the occurrence of side effects and the socioeconomic costs possibly associated with it. In haematology, in the particular case of Chronic Myeloid Leukemia, the "ADAGIO" study performed by Noens and co-workers demonstrated that therapeutic observance is lower than the practitioners, the patients and the family members believe it is. This lack of adhesion can engender a decrease of the efficiency of treatment, in particular by imatinib. Factors such as the chronicity of the disease and the length of treatment modify therapeutic adhesion over time. Simple methods, addressing both the patient and the doctor should be developed to improve this therapeutic adhesion. [less ▲]

Detailed reference viewed: 326 (4 ULiège)