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See detailSynthese bibliographique: problematique de la jacinthe d'eau, Eichhornia crassipes, dans les regions tropicales et subtropicales du monde, notamment son eradication par la lutte biologique au moyen des phytopathogenes.
Dagno, Karim ULg; Lahlali, R.; Friel, D. et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment (2007), 11(4), 299-311

Water hyacinth, probably originating from South America, grows between 35th North and South parallels of the planet. It was introduced into several regions of the world as ornamental plant, where it ... [more ▼]

Water hyacinth, probably originating from South America, grows between 35th North and South parallels of the planet. It was introduced into several regions of the world as ornamental plant, where it became later one of the most dangerous world water weed. Its infestation can be controlled by physical and chemical treatments. However, these methods are expensive and dangerous for human health and environment. Moreover, following Western legislations example, those of developing countries are highly restrictive against authorised chemical molecules. Consequently, a growing interest was given to alternative solutions, such as biological control. That control using insects, fi shes and mammiferes against water hyacinth could be strengthened with the application of mycoherbicides. These mycoherbicides are more respectful for environment and public health and seem to constitute an additional realistic alternative for water hyacinth durable management. [less ▲]

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See detailUse of molecular techniques in elucidating the action mechanisms of fungal biocontrol agents
Massart, Sébastien ULg; Jijakli, Haissam ULg

in Journal of Microbiological Methods (2007), 69

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See detailRevue Internationale des Droits de l'Antiquité LV (2007) (parue en septembre 2008)
Gerkens, Jean-François ULg

in Revue Internationale des Droits de l'Antiquité (2007), LIV

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See detailRéponses de Cedrus atlantica aux changements climatiques passés et futurs
Demarteau, Maxime; François, Louis ULg; Cheddadi, Rachid et al

in Geo-Eco-Trop : Revue Internationale de Géologie, de Géographie et d'Ecologie Tropicales (2007)

This work addresses the responses of the Atlas Mountain Cedar tree (Cedrus atlantica Manetti) when faced with past and future climactic changes. The ecological study of this species proposes three ... [more ▼]

This work addresses the responses of the Atlas Mountain Cedar tree (Cedrus atlantica Manetti) when faced with past and future climactic changes. The ecological study of this species proposes three simulations based on reliable and precise data: - Simulation in 6000 B.P. with the GCM UBRIS-HadCM3M2 climatic data - Simulation in the year 2000 with NEW et al. climactic data (2002) - Simulation in the year 2100 with the ARPEGE Climactic Model data - following the IPCC's scenario A2 These simulations were realized using the CARAIB model, which simulates Carbon stocks in vegetation and Carbon flux between vegetation, soil and atmosphere. In part one, the Moroccan Atlas Mountains, which constitute the principal natural area of the Atlas Cedar tree are described in detail. The different data describing this species' distribution at three periods are summarized: 1) at the present time, 2) at Holocene period and 3) at the end of the Upper Pleniglacial period . The distribution of the species is specified. A map of the Cedar tree's actual distribution in Morocco was drawn from a series of population maps - scale 1/25,000- kept at the Moroccan Ministry of Forestry and Water conservation. So as to improve the sequential study of fossils of Cedar pollen was defined the percentage threshold at which samples containing pollen from the Cedrus atlantica are described as autochtonous or allochthonous. The study of 514 samples of Moroccan Cedar pollen permittted to define this threshold as 1% with minimal risk of error. The last part of the work is focused on modelling. It starts with a description of IBM and CARAIB models used in the three simulations. The data essential for these models are reviewed. Considering the climactic data for these three periods, climate is globally warmer in 6000 BP and in 2100 than today, with the problems of drought becoming more severe in the future. The analysis of the three simulations brings us to two conclusions. Cedrus antlantica is sensitive to climactic change and shows that, at three different periods, its potential distribution areas are quite different. At 6000 BP, the species sought refuge in the high mountains of North Africa. Today's distribution is well simulated in our model. Its good survival in Europe makes it an interesting species for reforestation. In 2100, if IPCC's A2 scenario is validated, modifications in the Cedar's potential and real area of distribution will be considerable. The tree will find little refuge in North Africa. On the other hand, the climate of the land between the Northern Alps and the South of Sweden, associated with a strong concentration of CO2 in the atmosphere may well provide it with an acceptable environment. [less ▲]

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See detailLinear and curvilinear effects of inbreeding on production traits for walloon Holstein cows
Croquet, Coraline; Mayeres, Patrick; Gillon, Alain ULg et al

in Journal of Dairy Science (2007), 90(1), 465-471

The nonlinear effects of inbreeding were studied by comparing linear and curvilinear regression models of phenotypic performances on inbreeding coefficients for production traits (milk, fat, and protein ... [more ▼]

The nonlinear effects of inbreeding were studied by comparing linear and curvilinear regression models of phenotypic performances on inbreeding coefficients for production traits (milk, fat, and protein yields) of Holstein cows in their first lactation. Three different regression models (linear, quadratic, and cubic) were introduced separately into a single-trait, single-lactation, random regression test-day model. The significance of the different regression coefficients was studied based on a t-test after estimation of error variances and covariances associated with the different regression coefficients. All of the tested regression coefficients were significantly different from 0. The traditional regression coefficients of milk, fat, and protein yields on inbreeding were, respectively, -22.10, -1.10, and -0.72 kg for Holstein cows in their first lactation. However, the estimates of 305-d production losses for various classes of animals based on inbreeding coefficients showed that the effect of inbreeding was not a linear function of the percentage of inbreeding. The 305-d milk yield loss profiles attributable to inbreeding, obtained by the various regression models, were different. However, for inbreeding coefficients between 0 and 10%, these differences were small. [less ▲]

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See detailBilici Faruk, Louis XIV et son projet de conquête d'Istanbul
Bauden, Frédéric ULg

in Bulletin Critique des Annales Islamologiques (2007), 23

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See detailLes spolia (opima) dans l'Enéide et la "restauration" du temple de Jupiter Feretrius par Auguste
Rochette, Bruno ULg

in Denooz; Dortu, Véronique; Steinmetz, Rudy (Eds.) Mosaïque. Hommages à Pierre Somville (2007)

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See detailRespiratory distress syndrome in full-term newborn calves
Rollin, Frédéric ULg; Danlois, Fabien; Aliaoui, Hamani et al

Conference (2007)

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See detailFirst steps to model milk urea in a management perspective
Bastin, Catherine ULg; Gillon, Alain ULg; Gengler, Nicolas ULg

in Journal of Dairy Science (2007), 90 - Suppl 1

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See detailOxygen consumption of equine articular chondrocytes: Influence of applied oxygen tension and glucose concentration during culture.
Schneider, Nicole ULg; Mouithys-Mickalad, Ange ULg; Lejeune, Jean-Philippe ULg et al

in Cell Biology International (2007), 31

We investigated the oxygen (O2) uptake of equine articular chondrocytes to assess their reactions to anoxia/re-oxygenation. They were cultured under 5% or 21% gas phase O2 and at glucose concentrations of ... [more ▼]

We investigated the oxygen (O2) uptake of equine articular chondrocytes to assess their reactions to anoxia/re-oxygenation. They were cultured under 5% or 21% gas phase O2 and at glucose concentrations of 0, 1.0 or 4.5 g/L in the culture medium (n = 3). Afterwards, the O2 consumption rate of the chondrocytes was monitored (oxymetry) before and after an anoxia period of 25 min. The glucose consumption and lactate release were measured at the end of the re-oxygenation period. The chondrocytes showed a minimal O2 consumption rate, which was hardly changed by anoxia. Independently from the O2 tension, glucose uptake by the cells was about 30% of the available culture medium glucose, thus higher for cells at 4.5 g/L glucose (n = 3). Lactate release was also independent from O2 tension, but lower for cells at 4.5 g/L glucose (n = 3). Our observations indicated that O2 consumption by equine chondrocytes was very low despite a functional mitochondrial respiratory chain, and nearly insensitive to anoxia/re-oxygenation. But the chondrocytes metabolism was modified by an excess of O2 and glucose. [less ▲]

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See detailModave, Pont-de-Bonne. Les fortifications du "Rocher du vieux-Château".
Delye, Emmanuel ULg

in Dejardin, Valérie; Maquet, Julien (Eds.) Le patrimoine militaire de Wallonie (2007)

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See detailLes céréales dans le monde : besoin, production, flux
Burny, Philippe ULg

Diverse speeche and writing (2007)

Présentation de tableaux et figures relatifs aux statistiques concernant la superficie, le rendement, la production, le nombre d'exploitations, le commerce extérieur, le taux d'auto-approvisionnement, les ... [more ▼]

Présentation de tableaux et figures relatifs aux statistiques concernant la superficie, le rendement, la production, le nombre d'exploitations, le commerce extérieur, le taux d'auto-approvisionnement, les utilisations des céréales en Belgique. Présentation des chiffres principaux relatifs aux céréales dans le monde et dans l'Union européenne. [less ▲]

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See detailCompte rendu de : S. RUSSO, Le calzature nei papiri di età greco-romana
Rochette, Bruno ULg

in Bibliotheca Orientalis (2007)

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See detailDesign, synthesis and pharmacological evaluation of sulfonylureas and sulfonycyanoguanidines as thromboxane A2 receptor antagonists. Insights into selectivity between thromboxane A2 receptor isoforms (TPα et TPβ)
Hanson, Julien ULg

Doctoral thesis (2007)

Thromboxane A2 (TXA2) is an important mediator metabolized from arachidonic acid through the cyclooxygenase pathway, mainly in platelets and macrophages. It is a potent inducer of platelet aggregation and ... [more ▼]

Thromboxane A2 (TXA2) is an important mediator metabolized from arachidonic acid through the cyclooxygenase pathway, mainly in platelets and macrophages. It is a potent inducer of platelet aggregation and smooth muscle contraction. Its overproduction has been detected in pathologies such as stroke, asthma, myocardial infarction or atherosclerosis. The action of TXA2 is mediated by a specific G-protein coupled receptor (TP) of which two alternative spliced isoforms, TPalpha and TPbeta, have been described. The exact role of these two isoforms is not clearly understood. However, recent studies have described their implications in vascular physiology and pathology. The inhibition of the action of TXA2 on platelets and blood vessels would be interesting as original therapies against cardiovascular diseases. Consequently, the design of TP receptor antagonists remains of great interest in cardiovascular medicine. In the laboratory of medicinal chemistry (University of Liège, Belgium), several nitrobenzenesulfonylureas, derived from torasemide (a loop diuretic), have been previously described as TP receptor antagonists. Two compounds, BM573 and BM613 were among the most interesting molecules identified in that previous work. The present project is divided in two parts. First, we have determined the pharmacological properties of BM573 and BM613 as thromboxane synthase inhibitors and TP receptor antagonists, in vitro and in vivo. In our assays, these two compounds were proved to have high affinity for both TPalpha and TPbeta, to be potent antiplatelet agents, to inhibit thromboxane synthase and TP-mediated smooth muscle contraction. Additionally, they significantly reduced the size of the thrombus in a rat model of ferric chloride-induced arterial thrombosis. Consequently, we demonstrated that the TP receptor antagonists BM573 and BM613, belonging to the chemical family of nitrobenzenesulfonylureas, could be regarded as antiplatelet and antithrombotic agents potentially useful in thromboxane-related diseases such as stroke or myocardial infarction. Secondly, given the interesting pharmacological profile of BM573 and BM613, we have designed and synthesized several series of compounds derived from these two agents. We have evaluated the binding properties (affinity) of the first generation (+/- 35 original derivatives) of compounds on either TPalpha or TPbeta, transiently expressed in COS-7 cell lines. Additionally, we have measured the ability of our drugs to inhibit the intracellular calcium mobilization upon TPalpha or TPbeta stimulation. To confirm our results, we also assessed the antiplatelet properties of our drugs by means of determination of inhibition of human platelet aggregation. On the basis of the results obtained with these in vitro assays, we have synthesized and evaluated a second generation of derivatives (+/- 35 original compounds) and improved the selectivity of several original compounds for TP receptor isoforms. The originality of this work was to evaluate a large library of synthetic compounds on both TP receptor isoforms, using specific pharmacological tests. By means of structure-activity relationship studies, we were able to identify chemical groups implicated in selectivity and to propose lead compounds for development of highly specific TPalpha or TPbeta antagonists. Besides, we have identified an in vivo drug candidates for prevention of thrombosis and pathological platelet aggregation. [less ▲]

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