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See detailLa neuropathie avec hypersensibilite hereditaire a la pression ou neuropathie tomaculaire
Tinant, France ULg; Zeevaert, Bernard ULg; Benkirane, H. et al

in Revue Médicale de Liège (2002), 57(10), 651-4

Hereditary neuropathy liability to pressure palsies is characterized by recurring accesses of painless paralysis at the level of various nerves likely to be compressed. This affection remains ... [more ▼]

Hereditary neuropathy liability to pressure palsies is characterized by recurring accesses of painless paralysis at the level of various nerves likely to be compressed. This affection remains underdiagnosed because of its usually benign course, sometimes without any symptom. The diagnosis is supported by clinical and electrophysiological data associated with, in the majority of patients, a deletion of one of the alleles coding for protein PMP 22 on the level of the locus 17p11.2. [less ▲]

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See detailValor Nutricional de las plantas acuaticas Azolla y Salvinia en cerdos
Rosales, A.; Quintero, J.; Buritica, A. et al

in XII Encuentro Nacional de Zootecnia (2002, October)

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See detailValor nutricional de la hoja de nacedero (Trichanthera gigantea) y de boré (Xhantosoma sp.) en cerdos
Caicedo, A. L.; Quirama, A. M.; Londoño, A. M. et al

in XII Encuentro Nacional de Zootecnia (2002, October)

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See detailA family of MMA approximations for structural optimization
Bruyneel, Michaël ULg; Duysinx, Pierre ULg; Fleury, Claude ULg

in Structural and Multidisciplinary Optimization (2002), 24(4), 263-276

This paper proposes a new first-order approximation scheme used for solving structural optimization problems. It is based on approximations of the MMA family (MMA and GCMMA), but it utilizes the gradients ... [more ▼]

This paper proposes a new first-order approximation scheme used for solving structural optimization problems. It is based on approximations of the MMA family (MMA and GCMMA), but it utilizes the gradients and/or the function values at two successive design points to improve the quality of the approximation. In addition, this scheme can consider simultaneously monotonous and nonmonotonous structural behaviour. According to the characteristics of the treated problem, one of the approximations or a mix of them is automatically selected. Based on this approach, the accuracy of the approximated subproblems is improved and the solution process can be sped up. Numerical results compare the effectiveness of the method with previously derived approximations of the MMA family for shape optimization of trusses and for composite design problems. The benefit of using mixed approximations is also discussed. [less ▲]

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See detailArterial elastance and heart-arterial coupling in aortic regurgitation are determined by aortic leak severity
Segers, P.; Morimont, Philippe ULg; Kolh, Philippe ULg et al

in American Heart Journal (2002), 144(4), 568-576

Background In aortic valve regurgitation (AR), aortic leak severity modulates left ventricle (LV) arterial system interaction. The aim of this study was to assess (1) how arterial elastance (E-a ... [more ▼]

Background In aortic valve regurgitation (AR), aortic leak severity modulates left ventricle (LV) arterial system interaction. The aim of this study was to assess (1) how arterial elastance (E-a), calculated as the ratio of LV end-systolic pressure and stroke volume, relates to arterial properties and leak severity and (2) the validity of E-a/E-max (with E-max the slope of the-end-systolic pressure-volume relation) as a heart-arterial coupling parameter in AR. Methods and Results Our work is based on human data obtained from a study on vascular adaptation in chronic AR. These data allowed us to assess the parameters of a computer model of heart-arterial interaction. In particular, total peripheral resistance (R) and aortic leak severity-expressed as leak resistance (R-L,R-ao)-were quantified for different patient subgroups (group I/IIa/IIb: E-max = 2.15/0.62/0.47 mm Hg/mL; E-a = 1.24/0.66/0.90 mm Hg/mL; R = 1.9/0.6/0.85 mm Hg-s/mL, R-L,R-ao = 0.35/0.05/0.20 mm Hg-s/mL). A parameter study demonstrated that R-L,R-ao was the main determinant of E-a. With all other parameters constant, valve repair would increase E-a to 2.81, 1.08, and 1.54 mm Hg/mL in groups I,IIa, and IIb, respectively. For a given E-a/E-max, LV pump efficiency (estimated as the ratio of stroke work and LV systolic pressure-volume area) was lower than the theoretical predicted value, except for the simulations with intact aortic valve. Conclusions In AR(a) E-a is determined by aortic leak severity rather than by arterial system properties. Using E-a/E-max as a coupling parameter in general or as a mechanico-energetic regulatory parameter in particular is questionable. [less ▲]

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See detailTowards a Belgian Consensus for prevention of perinatal group B streptococcal disease
MELIN, Pierrette ULg; Verschraegen, G.; Mahieu, Ludo et al

Conference (2002, October)

Background & objectives: In Belgium, as in many other countries, group B Streptococcus (GBS) is still the leading cause of sepsis and meningitis in neonates. In 2001, though no Belgian guidelines for ... [more ▼]

Background & objectives: In Belgium, as in many other countries, group B Streptococcus (GBS) is still the leading cause of sepsis and meningitis in neonates. In 2001, though no Belgian guidelines for their prevention were available, in some hospitals, obstetrical programmes included a GBS prevention policy. With an aim to reach a Belgian consensus for the prevention of perinatal group B streptococcal disease, a national consensum meeting was organized in 2001. We report here our experience and findings of this meeting. Methods: In November 2001, obstetricians, neonatologists, microbiologists and infectious diseases specialists were invited to participate in a GBS symposium. International and Belgian speakers presented epidemiological aspects, argued comparative cost-effectiveness of different approaches for prevention and debated technical and practical problems. Management of neonates with risk factors for GBS disease and progress in GBS vaccines were also included in the programme. Further results about Belgian obstetricians’ practice and compliance to a policy for prevention of neonatal GBS diseases, as answered in two mail surveys, were commented and discussed. In an interactive session at the end, each participant was asked to vote on the key points related to the different steps of the ideal prevention strategy to recommend. Results: For the main questions, 94 per cent of participants choose a screening-based approach and 94 per cent shifted from the current use of ampicillin to penicillin as first choice for antimicrobial prophylaxis. Further, 79 per cent voted for an approach with integrated neonatal prophylaxis for selected neonates at high risk for GBS disease and 47 per cent voted for a strategy based on an intrapartum rapid screening-based approach. Interpretation & conclusion: The state of the question by different speakers, the data from Belgian epidemiology, and the debate about cost-effectiveness of different approaches led to a massive vote in favour of the universal screening-based approach. Based on these results, a working group has been appointed by the Ministry of Health to draft and edit Belgian recommendations for the prevention of perinatal GBS disease. [less ▲]

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See detailIndex of local response to geomagnetic activity for use in the short-term ionospheric forecast
Stankov, Stanimir; Jakowski, Norbert; Wehrenpfenning, A. et al

in Proceedings of the COST271 2002 workshop (2002, October)

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See detailImproved operational model for real-time reconstruction of the electron density profile at a single ionosonde location
Stankov, Stanimir; Warnant, René ULg; Jodogne, Jean-Claude

in Proceedings of the COST271 2002 workshop (2002, October)

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See detailDetermination of organohalogenated contaminants in liver of harbour porpoises (Phocoena phocoena) stranded on the Belgian North Sea coast
Covaci, Adrian; Van de Vijver, Kristin Inneke; De Coen, Wim et al

in Marine Pollution Bulletin (2002), 44(10),

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See detailEstimation de la résistance ultime de poutre-navire: Analyse comparative de méthodes sur frégates
Rigo, Philippe ULg; Quesnel, T.; Toderan, C. et al

in ATMA 2002, Association Technique Maritime et Aéronautique, 100ème Session (Article 2- Séance 1), www.atma.asso.fr, 19p. (2002, October)

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See detailSputum eosinophil count in a large population of patients with mild to moderate steroid-naive asthma: distribution and relationship with methacholine bronchial hyperresponsiveness
Louis, Renaud ULg; Sele, Jocelyne ULg; Henket, Monique ULg et al

in Allergy (2002), 57(10), 907-912

BACKGROUND: Although airway eosinophilia is seen as a cardinal feature of asthma, data eosinophilia are still lacking on the proportion of the asthma group exhibiting raised airway eosinophilia. This ... [more ▼]

BACKGROUND: Although airway eosinophilia is seen as a cardinal feature of asthma, data eosinophilia are still lacking on the proportion of the asthma group exhibiting raised airway eosinophilia. This study aimed to assess the distribution of sputum eosinophil count and its relationship with methacholine bronchial hyperresponsiveness in mild to moderate steroid-naive asthmatic people. METHODS: Sputum was induced by inhalation of hypertonic saline (NaCl 4.5%) in 118 mild to moderate steroid-naive asthmatic people consecutively recruited from our outpatient clinic, and in 44 healthy people. The asthma group was selected on the basis of an forced expiratory volume in 1 s (FEV(1)) of > or = 70% predicted, and a provocative methacholine concentration causing a fall of 20% in FEV(1) (PC20 methacholine; PC(20)M) < or = 16 mg/ml. RESULTS: In the asthma group, the median (range) of the percentage and the absolute values of sputum eosinophils were 4.8% (0-75) and 38 10(3)/g (0-14,191), respectively, vs 0% (0-2.3) (P < 0.001) and 0 10(3)/g (0-53) (P < 0.001) in healthy participants. Based on the 95% percentile for normal values calculated from our healthy group, 69% of the asthma group had significantly raised sputum eosinophil count (that is > 2%). In the asthma group, multiple regression analysis followed by a stepwise procedure revealed that sputum eosinophil count was significantly and inversely associated with PC(20)M accounting for 16% of its total variance (P < 0.001) while neutrophil counts positively related to PC(20)M accounting for 4% of total variance (P < 0.05). By contrast, no significant relationship was found between either eosinophil or neutrophil counts and the slope of forced vital capacity (FVC) vs FEV(1) from the methacholine challenge. CONCLUSIONS: We conclude that two-thirds of people in the mild to moderate asthma group had increased sputum eosinophilia, which plays a limited role in determining the degree of methacholine airway hyperresponsiveness. [less ▲]

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See detailPositive and negative aspects of « Sport + Studies Programmes » organized at secondary school level, perceived by athletes and their classmates
Cloes, Marc ULg; Schelings, Virginie; Ledent, Maryse et al

Poster (2002, October)

In several sports, athletes reaching the world-class level have experienced hard years of practice. Training must be intensive and respect high quality criteria. Today, promising teenagers are enrolled in ... [more ▼]

In several sports, athletes reaching the world-class level have experienced hard years of practice. Training must be intensive and respect high quality criteria. Today, promising teenagers are enrolled in sport programmes. However sport career achievement being so hazardous, it is necessary to guarantee the best school preparation to youths following the way to high level sport. ... [less ▲]

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See detailMatrix metalloproteinase-9 contributes to choroidal neovascularization
Lambert, Vincent ULg; Munaut, Carine ULg; Jost, M. et al

in American Journal of Pathology (2002), 161(4), 1247-1253

Age-related macular degeneration (AMD) is the primary cause of irreversible photoreceptors loss in adult patients and current therapies are limited. Increased levels of matrix metalloproteinases (MMPs ... [more ▼]

Age-related macular degeneration (AMD) is the primary cause of irreversible photoreceptors loss in adult patients and current therapies are limited. Increased levels of matrix metalloproteinases (MMPs) have been documented in neovascularization of severe ocular pathologies such as AMD and proliferative diabetic retinopathy. We report here that MMP-9 (gelatinase B) expression is induced and temporally regulated in the course of experimental choroidal neovascularization. We used transgenic mice expressing beta-galactosidase reporter gene under the dependence of MMP-9 promoter and RT-PCR analysis on choroidal neovascular structures microdissected from serial sections by laser pressure catapulting to show that MMP-9 expression is up-regulated concomitantly with the appearance of inflammatory cells in the subretinal lesion. In mice deficient in MMP-9 expression the development of choroidal neovascularization induced by laser photocoagulation still occurred, but at a reduced level. [less ▲]

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See detailThermal instability of a rotating saturated porous medium heated from below and submitted to rotation
Desaive, Thomas ULg; Hennenberg, M.; Lebon, Georgy ULg

in European Physical Journal B -- Condensed Matter (2002), 29(4), 641-647

In this work, we study the problem of onset of thermal convection in a rotating saturated porous medium heated from below. The effect of rotation is restricted to the Coriolis force, neglecting thus the ... [more ▼]

In this work, we study the problem of onset of thermal convection in a rotating saturated porous medium heated from below. The effect of rotation is restricted to the Coriolis force, neglecting thus the centrifugal effects, the porous medium is described by Brinkman's model. The linear eigenvalue problem is solved by means of a modified Galerkin method. The behavior of the critical temperature gradient is discussed in terms of various parameters of the system for both stationary and overstable convections. Finally a weakly nonlinear analysis is provided to derive amplitude equations and to study the onset of Kuppers-Lortz instability. [less ▲]

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See detailHow many nursery pigs can eat at one wet/dry feeder space
Laitat, Martine ULg; Dewey

Article for general public (2002)

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See detailFaites-vous de la grammaire, un peu, beaucoup, passionnément, pas du tout ?
Defays, Jean-Marc ULg

in Echec à l'Echec (2002), 151

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See detailThe mechanical effects of short-circuit currents in open air substations (Part II)
Lilien, Jean-Louis ULg; Declercq, Guy; El adnani, Mustapha et al

Book published by CIGRE (2002)

This book is a companion book of teh CIGRE brochure N° 105 (1996) on the same subject. It evaluates short-circuit mechanical effects and corresponding design loads in substation. It includes both rigid ... [more ▼]

This book is a companion book of teh CIGRE brochure N° 105 (1996) on the same subject. It evaluates short-circuit mechanical effects and corresponding design loads in substation. It includes both rigid and flexible bus-bars, Ac and DC network. It is divided in two volumes, the second one is giving numerous data and tests results of short-circuit. The first volume is detailing methods (simplified, medium and advanced ) to solve these problems. [less ▲]

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See detailThe lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways.
Dejardin, Emmanuel ULg; Droin, Nathalie; Delhase, Mireille et al

in Immunity (2002), 17

The lymphotoxin-beta receptor (LTbetaR) plays critical roles in inflammation and lymphoid organogenesis through activation of NF-kappaB. In addition to activation of the classical NF-kappaB, ligation of ... [more ▼]

The lymphotoxin-beta receptor (LTbetaR) plays critical roles in inflammation and lymphoid organogenesis through activation of NF-kappaB. In addition to activation of the classical NF-kappaB, ligation of this receptor induces the processing of the cytosolic NF-kappaB2/p100 precursor to yield the mature p52 subunit, followed by translocation of p52 to the nucleus. This activation of NF-kappaB2 requires NIK and IKKalpha, while NEMO/IKKgamma is dispensable for p100 processing. IKKbeta-dependent activation of canonical NF-kappaB is required for the expression but not processing of p100 and for the expression of proinflammatory molecules including VCAM-1, MIP-1beta, and MIP-2 in response to LTbetaR ligation. In contrast, IKKalpha controls the induction by LTbetaR ligation of chemokines and cytokines involved in lymphoid organogenesis, including SLC, BLC, ELC, SDF1, and BAFF. [less ▲]

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