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See detailAdaptive remeshing for incremental forming simulation
Lequesne, Cédric ULg; Henrard, Christophe ULg; Bouffioux, Chantal ULg et al

in Pavel, H. (Ed.) Proceedings of the 7th International Conference and Workshop on Numerical Simulation od 3D Sheet Metal Forming Processes (NUMISHEET 2008) (2008)

Incremental forming of aluminium sheets has been modelled by finite element simulations. However the computation time was prohibitive because the tool deforms every part of the sheet and the mesh along ... [more ▼]

Incremental forming of aluminium sheets has been modelled by finite element simulations. However the computation time was prohibitive because the tool deforms every part of the sheet and the mesh along the tool path must be very fine. Therefore, an adaptive remeshing method has been developed. The elements that are close to the tool are divided into smaller elements in order to have a fine mesh where high deformations occur. Consequently, some new nodes become inconsistent with the non-refined neighbouring elements. To overcome that problem, their displacements are constrained, i.e. dependent on their master nodes displacements. The data concerning these new nodes and elements are stored in a linked list, which is a fundamental data structure. It consists of a sequence of cells, each containing data fields and a pointer towards the next cell. The goal of this article is to explain the developments performed in the finite element code, to validate the adaptive remeshing technique and to measure its efficiency using the line test simulation. During this test, which is a simple incremental forming test, a clamped sheet is deformed by a spherical tool moving along a linear path. [less ▲]

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See detailCharacterization of the proneural gene regulatory network during mouse telencephalon development.
Gohlke, Julia M; Armant, Olivier; Parham, Frederick M et al

in BMC Biology (2008), 6

BACKGROUND: The proneural proteins Mash1 and Ngn2 are key cell autonomous regulators of neurogenesis in the mammalian central nervous system, yet little is known about the molecular pathways regulated by ... [more ▼]

BACKGROUND: The proneural proteins Mash1 and Ngn2 are key cell autonomous regulators of neurogenesis in the mammalian central nervous system, yet little is known about the molecular pathways regulated by these transcription factors. RESULTS: Here we identify the downstream effectors of proneural genes in the telencephalon using a genomic approach to analyze the transcriptome of mice that are either lacking or overexpressing proneural genes. Novel targets of Ngn2 and/or Mash1 were identified, such as members of the Notch and Wnt pathways, and proteins involved in adhesion and signal transduction. Next, we searched the non-coding sequence surrounding the predicted proneural downstream effector genes for evolutionarily conserved transcription factor binding sites associated with newly defined consensus binding sites for Ngn2 and Mash1. This allowed us to identify potential novel co-factors and co-regulators for proneural proteins, including Creb, Tcf/Lef, Pou-domain containing transcription factors, Sox9, and Mef2a. Finally, a gene regulatory network was delineated using a novel Bayesian-based algorithm that can incorporate information from diverse datasets. CONCLUSION: Together, these data shed light on the molecular pathways regulated by proneural genes and demonstrate that the integration of experimentation with bioinformatics can guide both hypothesis testing and hypothesis generation. [less ▲]

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See detailL’entreprise virtuelle
Choffray, Jean-Marie ULg

in Ordre des Experts-Comptables Français (Ed.) Entreprise 2018 (2008)

Dans notre société de convenance, il y a tant de thèmes que l’on ne peut se permettre d’évoquer, qu’il est difficile de savoir par lequel ne pas commencer. A la réflexion, la question que posa, à l’issue ... [more ▼]

Dans notre société de convenance, il y a tant de thèmes que l’on ne peut se permettre d’évoquer, qu’il est difficile de savoir par lequel ne pas commencer. A la réflexion, la question que posa, à l’issue d’un séminaire récent, le dirigeant d’un grand groupe industriel, semble constituer un bon sujet à éviter : pour exister, une entreprise doit-elle "exister" ? [less ▲]

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See detailMultivessel coronary revascularization in patients with and without diabetes mellitus: 3-year follow-up of the ARTS-II (Arterial Revascularization Therapies Study-Part II) trial.
Daemen, Joost; Kuck, Karl Heinz; Macaya, Carlos et al

in Journal of the American College of Cardiology (2008), 52(24), 1957-67

OBJECTIVES: The purpose of this study was to assess the 3-year outcome of coronary artery bypass graft surgery (CABG) and percutaneous coronary intervention (PCI) using sirolimus-eluting stents (SES) in ... [more ▼]

OBJECTIVES: The purpose of this study was to assess the 3-year outcome of coronary artery bypass graft surgery (CABG) and percutaneous coronary intervention (PCI) using sirolimus-eluting stents (SES) in patients who had multivessel coronary artery disease with and without diabetes mellitus. BACKGROUND: The optimal method of revascularization in diabetic patients remains in dispute. METHODS: The ARTS-II (Arterial Revascularization Therapies Study-Part II) trial is a single-arm study (n = 607) that included 159 diabetic patients treated with SES whose 3-year clinical outcome was compared with that of the historical diabetic and nondiabetic arms of the randomized ARTS-I trial (n = 1,205, including 96 diabetic patients in the CABG arm and 112 in the PCI arm). RESULTS: At 3 years, among nondiabetic patients, the incidence of the primary composite of death, CVA, myocardial infarction (MI), and repeat revascularization (major adverse cardiac and cerebrovascular events [MACCE]), was significantly lower in ARTS-II than in ARTS-I PCI (adjusted odds ratio [OR]: 0.41; 95% confidence interval [CI]: 0.26 to 0.64) and similar to ARTS-I CABG. The ARTS-II patients were at significantly lower risk for death, CVA, and MI as compared with both the ARTS-I PCI (adjusted OR: 0.55; 95% CI: 0.34 to 0.91) and ARTS-I CABG patients (adjusted OR: 0.56; 95% CI: 0.35 to 0.92). Among diabetic patients, the incidence of MACCE in ARTS-II was similar to that of both PCI and CABG in ARTS-I. Conversely, the incidence of death, CVA, and MI was significantly lower in ARTS-II than in ARTS-I PCI (adjusted OR: 0.67; 95% CI: 0.27 to 1.65) and was similar to that of ARTS-I CABG. CONCLUSIONS: At 3 years, PCI using SES for patients with multivessel coronary artery disease seems to be safer and more efficacious than PCI using bare-metal stents, irrespective of the diabetic status of the patient. Hence, PCI using SES appears to be a valuable alternative to CABG for both diabetic and nondiabetic patients. [less ▲]

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See detailLe commerce équitable : leçons d’expériences
Duquesne, Brigitte ULg; Lebailly, Philippe ULg

Conference (2008)

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See detailEt si entreprendre était une science ?
Choffray, Jean-Marie ULg

in Bouchikhi, Hamid (Ed.) L’art d’entreprendre, des idées pour agir (2008)

Ne pas échouer, c’est déjà un peu réussir… Peut-être même beaucoup !... L’objet de ce chapitre est de revoir les principales difficultés auxquelles un créateur d’entreprise est confronté au cours de la ... [more ▼]

Ne pas échouer, c’est déjà un peu réussir… Peut-être même beaucoup !... L’objet de ce chapitre est de revoir les principales difficultés auxquelles un créateur d’entreprise est confronté au cours de la période qui précède le lancement de son projet, ainsi que pendant les premières années de son développement. Ces pièges - et autres sources de risque - constituent autant d’invitations à l’erreur et donc d’étapes vers le succès s’ils sont évités. Si l’observation de ces conditions ne suffit pas à définir une « science d’entreprendre », elle illustre parfaitement que la création d’une entreprise n’est déjà plus un « art » !... [less ▲]

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See detailImportance des aides aux vaches allaitantes dans le revenu agricole en Région wallonne
Delille, Nicolas ULg; Bouquiaux, J. M.; Closset, M. F. et al

Poster (2008)

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See detailLandscape Dynamics And Habitat Selection By The Alien Invasive Fallopia (Polygonaceae) In Belgium
Tiebre, Marie-Solange; Saad, Layla ULg; Mahy, Grégory ULg

in Biodiversity & Conservation (2008), 17(10), 2357-2370

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See detailContribution Of Delayed Autonomous Selfing To Reproductive Success In Kosteletzkya Virginica
Ruan, Cj.; Zhou, Lj.; Zeng, Fy. et al

in Belgian Journal of Botany (2008), 141(1), 3-13

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See detailRentabilité des cultures céréalières en Région wallonne durant la période 2004-2006 et perspectives
Delille, Nicolas ULg; Gheysen, Marjorie; Vanorlé, L. et al

(2008)

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See detailLe projet DACEFI : contexte, philosophie et résultats attendus
Federspiel, M.; Vermeulen, Cédric ULg; Carr, B. et al

in Vermeulen, Cédric; Doucet, Jean-Louis (Eds.) Les premières forêts communautaires du Gabon : Récits d'une expérience pilote (2008)

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See detailGermination of Sorghum Under the Influences of Water Restriction and Temperature
Lobato, AKS; Oliveira Neto, CF; Costa, RCL et al

in Agricultural Journal (2008), 3(3), 220-224

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See detailEvaluation de l'impact économique du cotonnier sans gossypol en Côte d'Ivoire.
Zagbai, H. S.; Berti, Fabio ULg; Lebailly, Philippe ULg

in Tropicultura (2008), 26(1), 28-31

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See detailLa neurogenese adulte ou l'histoire d'un dogme qui s'ecroule.
Pirotte, Dorothée ULg; Rogister, Bernard ULg

in Revue Médicale de Liège (2008), 63(5-6), 245-50

The history of sciences is characterized by major discoveries, but also by challenges of theories or dogma previously established and accepted by everybody. One of the recent examples illustrating such a ... [more ▼]

The history of sciences is characterized by major discoveries, but also by challenges of theories or dogma previously established and accepted by everybody. One of the recent examples illustrating such a questioning relates to the demonstration of the persistence of a cerebral neurogenesis in the adult brain, including in human. This adult neurogenesis is however limited, both in space (it concerns only the subventricular zone and the gyrus dentatus in the hippocampus) and the type of newly-formed neurons (interneurones which most of them are GABAergic and present respectively in the olfactive bulb and CA1 area of the hippocampus). Moreover, this neurogenesis does not seem to be recruited after a brain lesion, a situation which explains why functional recovery when it is observed remains a consequence of brain plasticity. We thus legitimately address the question about the physiological role of this adult brain neurogenesis as well as a possible implication in the aetiology of various neurological disorders, like the neurodegenerative diseases or epilepsy, but also in psychiatric diseases like depression. [less ▲]

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See detailLes matières colorantes au début du Paléolithique supérieur
Salomon, Hélène ULg; Vignaud, Colette; Coquinot, Yvan et al

in Techné (2008)

A lot of settlements, some of which were occupied as long as 300 000 years ago, yielded small quantities of colouring matter. These quantities increased as time went by and as the palette of colours ... [more ▼]

A lot of settlements, some of which were occupied as long as 300 000 years ago, yielded small quantities of colouring matter. These quantities increased as time went by and as the palette of colours diversified, to reach a remarkable climax during the Upper Palaeolithic. Yet colouring matter has been widely ignored, notwithstanding the great potential information they contain about the technical knowledge, the cognitive capacities, the socio-cultural organisation of prehistoric societies and more generally about aesthetic and symbolic conceptions or  even language. The cave of Chauvet (Ardèche, France) is the most ancient testimony of cave drawing in Europe, with representations whose radiocarbon dating by AMS is 31 000 B.P. The origins of this form of art, which already evidences a perfect graphic mastery, are unknown and cannot be found in the previous periods. We thus have to search for clues of these artistic preoccupations in the colouring matter remains of more ancient cultures. But the use of colouring matter is far from limited to the production of parietal art, that was probably an exception among a large scope of more domestic uses, so far very little studied. We studied then a collection coming from the Chatelperronian layers in the “Grotte du Renne” (Arcy-sur-Cure, France), which was excavated in the 60’ by André Leroi-Gourhan. It is a very rich collection of pigments with various shades, which were systematically collected during the excavation. The ultimate purpose is to reconstitute the gestures that enabled the last Neanderthals in Europe to transform the colouring, abrasive, drying and prophylactic properties of these materials. This methodology also proposes to shed some light on their domestic and symbolic utilisations and to evidence the «chaînes opératoires» in the industry of colouring matter; and thus define the roles and the statutes of these materials in the societies of the Early Upper Palaeolithic period. [less ▲]

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See detailSivers asymmetry for the proton and the neutron
Scopetta, S.; Courtoy, Aurore ULg; Fratini, F. et al

in AIP Conference Proceedings (2008), 1056

A formalism is presented to evaluate the Sivers function in constituent quark models. A non-relativistic reduction of the scheme is performed and applied to the Isgur-Karl model. The results obtained are ... [more ▼]

A formalism is presented to evaluate the Sivers function in constituent quark models. A non-relativistic reduction of the scheme is performed and applied to the Isgur-Karl model. The results obtained are consistent with a sizable Sivers effect and the signs for the u and d flavor contributions turn out to be opposite. The Burkardt Sum Rule is fulfilled to a large extent. After the estimate of the QCD evolution of the results from the momentum scale of the model to the experimental one, a reasonable agreement with the available data is obtained. A calculation of nuclear effects in the extraction of neutron single spin asymmetries in semi-inclusive deep inelastic scattering off 3He is also described. In the kinematics of forth-coming experiments at JLab, it is found that the nuclear effects arising within an Impulse Approximation approach are under control. © American Institute of Physics. [less ▲]

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See detailOptimalisation des techniques prothetiques de rehabilitation orale grace a l'orthodontie: analyse d'un cas clinique.
Lies, Céline ULg; Fernandez, S.; Limme, Michel ULg et al

in Revue Médicale de Liège (2008), 63(10), 609-14

This clinical case underlines the importance of a multidisciplinary approach, prosthetic and orthodontic, for the achievement of an oral rehabilitation treatment plan. Preliminary orthodontic treatment ... [more ▼]

This clinical case underlines the importance of a multidisciplinary approach, prosthetic and orthodontic, for the achievement of an oral rehabilitation treatment plan. Preliminary orthodontic treatment has significantly improved, the position of some natural teeth, which can serve or not as a prosthetic abutment. This has produced a direct prosthetic benefit by limiting tissue reduction for preparation and by giving a better biomechanical and functional context to the restoration.Thus, after an orthodontic treatment step, lasting a year and a half, using both removable appliance and fixed appliance, prosthetic rehabilitation was possible. This included a fixed prosthesis and a removable prosthesis that gave a very satisfying an esthetic result and good masticatory function. [less ▲]

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