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See detailStudy of complex carbides obtained after solidification and thermal treatment in High Speed Steels
Tchuindjang, Jérôme Tchoufack ULg; Lecomte-Beckers, Jacqueline ULg

in Proceedings des journées annuelles de la Société belge de physique SBP-BSP (27 et 28 mai 2003) (2003, May)

High-speed steels (HSS) rolls are used in front finishing stands of hot strip mills. Good wear resistance and hardness at high temperature are defining characteristics of HSS. Many carbides are present in ... [more ▼]

High-speed steels (HSS) rolls are used in front finishing stands of hot strip mills. Good wear resistance and hardness at high temperature are defining characteristics of HSS. Many carbides are present in these alloys, each having different effects upon the final properties of HSS. As a result, the nature, the morphology and the amount of these carbides are factors of important concern. Optical microscopy combined with electron microscopy lead to quicker identification and characterization of HSS carbides. [less ▲]

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See detailL'exercice du contrôle de gestion en contexte PME : étude comparée des cas français, canadien et belge
Van Caillie, Didier ULg

in Association Francophone de Comptabilité (Ed.) Actes du 23ème Congrès de l'Association Francophone de Comptabilité (2003, May)

This paper compares practices in terms of management control emerging from field researches conducted respectively in France, Canada and Belgium and proposes a global synthetic model describing ... [more ▼]

This paper compares practices in terms of management control emerging from field researches conducted respectively in France, Canada and Belgium and proposes a global synthetic model describing specifcities of these practices. [less ▲]

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See detailTransactivation of vimentin by beta-catenin in human breast cancer cells
Gilles, Christine ULg; Polette, M.; Mestdagt, Mélanie ULg et al

in Cancer Research (2003), 63(10), 2658-2664

The cytoplasmic and nuclear redistribution of beta-catenin and the de novo expression of vimentin are frequently involved in the epithelial-to-mesenchymal transition associated with increased invasive ... [more ▼]

The cytoplasmic and nuclear redistribution of beta-catenin and the de novo expression of vimentin are frequently involved in the epithelial-to-mesenchymal transition associated with increased invasive/migratory properties of epithelial cells. Because beta-catenin can act as a coactivator of transcription through its binding to the T-cell factor (TCF)/lymphoid enhancer factor 1 transcription factor family, we have explored the possibility that beta-catenin/TCF could directly transactivate vimentin. We first compared vimentin expression in relation with the localization of beta-catenin in eight breast cancer cell lines displaying various degrees of invasiveness and in a model of cell migration using human mammary MCF10A cells. We could thus show a cytoplasmic and/or nuclear distribution of beta-catenin in invasive/migratory cells expressing vimentin, but not in noninvasive/stationary vimentin-negative cell lines. In addition, the human vimentin promoter was found to be up-regulated by beta-catenin and TCF-4 cotransfection. Varying with the cellular background, a diminution of this up-regulation was observed when the putative beta-catenin/TCF binding site of the vimentin promoter was mutated. Our results therefore demonstrate that the vimentin promoter is a target of the beta-catenin/TCF pathway and strongly suggest an implication of this regulation in epithelial cell migration/invasion. [less ▲]

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See detailDépistage et détection précoce des cancers : Pourquoi? Comment? Lesquels? Qui et où? A quel prix?
Castronovo, Vincenzo ULg

in Revue Médicale de Liège (2003), 58(5), 310-3

Cancer is fighting with cardiovascular diseases for the first place as the number one killer of humans living in industrialized countries. Several factors contribute to the high incidence of cancers. The ... [more ▼]

Cancer is fighting with cardiovascular diseases for the first place as the number one killer of humans living in industrialized countries. Several factors contribute to the high incidence of cancers. The spectacular increase in life expectancy of individuals living in these areas is certainly one of the major causes that explain the steady rise of the number of patients suffering and dying from cancer. For most cancers, when the issue is fatal, it is usually after a long morbidity period often very difficult for the patient and with heavy public health consequences. Thus, a major challenge that the health professionals are facing is the reduction of malignant disease incidence. Primary prevention would be certainly the most successful strategy. However, its implementation is of extreme difficulty. Secondary prevention, non-exclusive to the primary one, represents probably the best approach to decrease morbidity and mortality linked to these diseases. Screening and early diagnosis are the two axes of such a strategy. The first one concerns the detection of a malignant lesion in an asymptomatic patient. Early diagnosis implies to consider with attention and explore any signs or symptoms that can be easily missed by the patient or the doctor and, hence, could be the first indication of a progressing cancer. The impact of cancer screening on the mortality rate due to cancer is still the subject of intense debates, while the efficacy of early diagnosis is unanimously recognized. Still, it is cancer screening that is the center of most attentions.... [less ▲]

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See detailEstimation of fructose, glucose and sucrose released by inulin hydrolysis during food processing.
Chevalier, Jean-Paul; Paquot, Michel; Fougnies, C. et al

Poster (2003, May)

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See detailStudy of a model low-fat salad dressing formulated with inulin.
Blecker, Christophe ULg; Marti, J.; Chevalier, Jean-Paul et al

Poster (2003, May)

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See detailBioresorbable and bioactive composite materials based on polylactide foams filled with and coated by Bioglass (R) particles for tissue engineering applications
Boccaccini, Aldo R.; Notingher, I.; Maquet, Véronique et al

in Journal of Materials Science: Materials in Medicine (2003), 14(5), 443-450

Poly(DL-lactide) (PDLLA) foams and bioactive glass (Bioglass®) particles were used to form bioresorbable and bioactive composite scaffolds for applications in bone tissue engineering. A thermally induced ... [more ▼]

Poly(DL-lactide) (PDLLA) foams and bioactive glass (Bioglass®) particles were used to form bioresorbable and bioactive composite scaffolds for applications in bone tissue engineering. A thermally induced phase separation process was applied to prepare highly porous PDLLA foams filled with 10wt% Bioglass® particles. Stable and homogeneous layers of Bioglass® particles on the surface of the PDLLA/Bioglass® composite foams as well as infiltration of Bioglass® particles throughout the porous network were achieved using a slurry-dipping technique. The quality of the bioactive glass coatings was reproducible in terms of thickness and microstructure. In vitro studies in simulated body fluid (SBF) were performed to study the formation of hydroxyapatite (HA) on the surface of the PDLLA/Bioglass® composites, as an indication of the bioactivity of the materials. Formation of the HA layer after immersion in SBF was confirmed by X-ray diffraction and Raman spectroscopy measurements. The rate of HA formation in Bioglass®-coated samples was higher than that observed in non-coated samples. SEM analysis showed that the HA layer thickness rapidly increased with increasing time in SBF in the Bioglass®-coated samples. The high bioactivity of the developed composites suggests that the materials are attractive for use as bioactive, resorbable scaffolds in bone tissue engineering. [less ▲]

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See detailAVPRO-LBR5, an Initial Design Software Suite with Scantling Optimization Capabilities
Goubault, P.; Besnard, N.; Rigo, Philippe ULg

in IMDC’2003, Eighth International Marine Design Conference, Grèce, Edited by A. Papanikolaou (NTUA, Athènes), Vol2, May 2003 (2003, May)

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See detailHow to minimise production costs at the preliminary design stage - scantling optimization
Rigo, Philippe ULg

in IMDC’2003, Eighth International Marine Design Conference, Grèce,Vol2 (2003, May)

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See detailLeast Cost Optimisation of a Medium Capacity Gas Carrier
Rigo, Philippe ULg; Toderan, C.

in COMPIT’03, 2nd Int. EuroConference on Computer and IT Applications in the Maritime Industries,Hamburg, Ed. V. Bertram, 14-17 May 2003 (2003, May)

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See detailOrganising access to evidence-based medicine resources on the web
Delvenne, Catherine ULg; Pasleau, Françoise ULg

in Computer Methods & Programs in Biomedicine (2003), 71(1), 1-10

The continuing education is a challenge for health care professionals, considering the growing amount and variable quality of information in this field. In this context, we developed a method allowing ... [more ▼]

The continuing education is a challenge for health care professionals, considering the growing amount and variable quality of information in this field. In this context, we developed a method allowing clinicians to have a centralised access to the best current medical evidence supporting medical decision-making. Relevant data has been gathered according to the rules stated for Evidence-Based Medicine (EBM) and organised in a free-of-charge Web site, created by using common software applications. The general aim of our study was to encourage individual practice of EBM by providing tutorials as well as a selection of free access tools for searching medical information on the Web. In addition to the education part, we provided clinicians, through a Web interface, with up-to-date, accurate and quality data obtained from heterogeneous sources and presented in a full text format when available. The developed methodology has been applied to human prostate cancer. URL address: http://www.ebm.lib.ulg.ac.be/prostate/index.htm. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved. [less ▲]

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See detailRole of the thymus in the development of tolerance and autoimmunity towards the neuroendocrine system
Geenen, Vincent ULg; Brilot, Fabienne

in Annals of the New York Academy of Sciences (2003), 992

The thymus is the unique lymphoid organ inside which a confrontation occurs throughout life between neuroendocrine self-antigens and a recently evolved system with original recombination machinery driving ... [more ▼]

The thymus is the unique lymphoid organ inside which a confrontation occurs throughout life between neuroendocrine self-antigens and a recently evolved system with original recombination machinery driving random generation of immune response diversity. Through transcription of neuroendocrine genes in the thymus stromal network and expression of cognate receptors by immature T cells, the neuroendocrine system regulates early T cell differentiation. In addition and more specifically, intrathymic presentation of neuroendocrine self-antigens by, or in close association with, major histocompatibility complex (MHC) proteins is responsible for the establishment of central immune self-tolerance of neuroendocrine principles. All members of the insulin gene (INS) family are expressed in the thymus stroma according to a precise hierarchy and cell topography: IGF2 (thymic epithelial cells) > IGF1 (thymic macrophages) much greater than INS (thymic medullary epithelial cells and/or dendritic cells). Given this hierarchical pattern in gene expression, the protein IGF-2 is more tolerated than INS. Igf2 transcription is defective in the thymus of bio-breeding (BB) rat, one animal model of type 1 diabetes (T1DM). This thymus-specific defect in Igf2 expression may explain both the absence of central tolerance to INS-secreting beta cells and the lymphopenia (including lack of regulatory RT6(+) T cells) in diabetes-prone BB rats. INS B:9-23 and the homologous sequence of IGF-2 compete for binding to DQ8, an MHC class II allele conferring major susceptibility to T1DM. In young DQ8(+) T1DM patients, INS B:9-23 presentation by DQ8 elicits a dominant IFN-gamma secretion by isolated PBMCs, whereas presentation of the IGF-2 self-antigen promotes a dominant regulatory interleukin-10 secretion. These data demonstrate that opposite immune responses are driven by MHC presentation of a self-antigen (here, IGF-2) and an autoantigen (INS, as "altered" self). The important tolerogenic properties of thymic self-antigens deserve now to be exploited for prevention and/or cure of devastating autoimmune diseases such as T1DM. [less ▲]

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See detailOne phase rural distribution installation with direct connection to HV trunk line
Lilien, Jean-Louis ULg; Monfils, Pierre-André; Omboua, Alphonse

in 17th International Conference on Electricity Distribution - CIRED (2003, May)

One original application of the distribution network development, based on existing HV network, is presented for the rural electrification of developing countries. Supply of a few kVA to remote site needs ... [more ▼]

One original application of the distribution network development, based on existing HV network, is presented for the rural electrification of developing countries. Supply of a few kVA to remote site needs specific installations. We have developed, installed and experimented one practical application from April 17th, 2002 in Makola (Congo-Brazzaville, 30 km far from Pointe Noire). We have investigated the case where a HV OHL exists in the vicinity of the village. Our application is a one-phase connection to a 220 kV line with a local demand estimated at 50 kVA (about 500 people) in a first step. We have adapted the existing technology of SF6 inductive voltage transformer in order to supply 50 kVA instead of a few VA. The paper will present the problems met during the design of this specific installation compared to classical substation, and the results of first months of use. [less ▲]

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See detailDepistage des cancers du sein et du col de l'uterus: attitudes et comportements de la population feminine liegeoise
Escoyez, Bernadette; Mairiaux, Philippe ULg

in Revue Médicale de Liège (2003), 58(5), 319-26

Several surveys have shown that in Belgium the coverage of the female population for both breast and cervix cancers screening is too low and not evenly distributed in the target population. In order to ... [more ▼]

Several surveys have shown that in Belgium the coverage of the female population for both breast and cervix cancers screening is too low and not evenly distributed in the target population. In order to highlight modifiable behavioural factors about cancer screening and to know the profile of women who exhibit an inadequate preventive behaviour, a postal survey has been conducted in the city of Liege. A self-administrated questionnaire was sent to a randomised sample of 1.000 women from two age groups (25-37 and 45-57 years); 444 women returned the questionnaire (response rate: 45.4%). The results show that the responders who do not comply with the recommendations for cancer screening are more often unemployed women with a low educational level, women who have a poor perception of their health, or women who are not regularly followed by a gynaecologist. Those women have more often poor knowledge and wrong beliefs about prevention, a negative perception of the curability of a cancer detected early and of the efficacy of screening tests. In spite of an overrepresentation of women with an university degree among the responders, it was also observed that more than 1 woman out of 4 in the 25-37 years age group is not convinced of the pap smear efficacy. In view of these results, the design of screening campaigns for cancer prevention has to involve specific efforts targeted at under-privileged subgroups within the female population. [less ▲]

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See detailIn vitro pre-digestion to estimate fermentability of feedstuffs in pig large intestine
Boudry, Christelle ULg; Estrada, Fernando; Schoeling, Olivia et al

in Ball, Ronald O. (Ed.) Proceedings of the 9th International Symposium on Digestive Physiology in Pigs (2003, May)

The aim of this study was to compare ileal and faecal digestibilities to gas production in syringes, preceded or not by an in vitro enzymatic digestion of two pig diets containing different amounts of non ... [more ▼]

The aim of this study was to compare ileal and faecal digestibilities to gas production in syringes, preceded or not by an in vitro enzymatic digestion of two pig diets containing different amounts of non starch polysaccharides (NSP). In vivo, only nitrogen faecal digestibility differed between the two diets. Their enzymatic pre-digestion led to a higher gas production after 16 h of incubation in syringes for the diet with the lowest N faecel digestibility but not without pre-digestion. We may conclude that an in vitro pre-digestion before incubation in syringes is necessary to evaluate feed fermentescibility in pig large intestine. [less ▲]

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See detailApplications de l'approche bayésienne à la représentation des pluies mensuelles africaines par la loi des fuites.
Bernier, Jacques; Parent, Eric; Boreux, Jean-Jacques ULg

Conference (2003, May)

Ce texte présente une analyse bayésienne d'un processus ponctuel marqué particulier (la loi des fuites) avec application à des problèmes de modélisation environnementale hydrométéorologique sur les ... [more ▼]

Ce texte présente une analyse bayésienne d'un processus ponctuel marqué particulier (la loi des fuites) avec application à des problèmes de modélisation environnementale hydrométéorologique sur les données africaines de Ghezala (Tunisie) et Ataktamé (Togo). [less ▲]

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See detailContribution to the optimization of closed-loop multibody systems : application to parallel manipulators
Collard, Jean-François; Fisette, Paul; Duysinx, Pierre ULg

in Proceedings of the 5th World Congress of Structural and Multidisciplinary Optimization WCSMO5 (2003, May)

This paper describes an original and robust method to optimize the design of closed-loop mechanisms, especially parallel manipulators. In other words, these mechanisms include assembling constraints we ... [more ▼]

This paper describes an original and robust method to optimize the design of closed-loop mechanisms, especially parallel manipulators. In other words, these mechanisms include assembling constraints we solved using a Newton-Raphson algorithm which may fail when the Jacobian matrix of the constraints is ill-conditioned. Therefore, the technique we propose takes advantage of that conditioning to penalize properly the objective function. Applications are shown: on the one hand, a simple example about the design of a planar ejector and, on the other hand, more realistic examples about the kinematical properties of parallel robots, in particular Delta-type and HexaSlide-type manipulators. [less ▲]

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See detailLe douglas sur substrat calcaire. Etude de ses potentialités forestières en Calestienne
Mouchet, F.; Claessens, Hugues ULg; Laroche, J.

in Forêt Wallonne (2003), (64), 27-32

Pour la sylviculture, la principale caractéristique de la Calestienne est très certainement la combinaison entre sa haute biodiversité et sa faible aptitude à la production de bois. Ainsi, la difficulté ... [more ▼]

Pour la sylviculture, la principale caractéristique de la Calestienne est très certainement la combinaison entre sa haute biodiversité et sa faible aptitude à la production de bois. Ainsi, la difficulté de trouver une essence économiquement rentable pouvant valoriser des sols souvent très ingrats a poussé plusieurs générations de forestiers à effectuer de nombreux essais sylviculturaux. Parmi ceux-ci, la célèbre introduction du pin noir, et plus récemment et plus discrètement, celle du douglas. [less ▲]

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See detailLe point sur la maladie du hêtre en Wallonie
Huart, O.; De Proft, M.; Grégoire, J. C. et al

in Forêt Wallonne (2003), (64), 2-20

Le hêtre, troisième essence feuillue (en volume) de Wallonie, est actuellement victime, essentiellement en Ardenne et en Gaume, d’un important problème sanitaire mettant en jeu des attaques d’insectes et ... [more ▼]

Le hêtre, troisième essence feuillue (en volume) de Wallonie, est actuellement victime, essentiellement en Ardenne et en Gaume, d’un important problème sanitaire mettant en jeu des attaques d’insectes et de champignons, communément appelé « maladie du hêtre ». Les premiers symptômes inquiétants du phénomène ont été identifiés à l’automne 1999, puis se sont considérablement amplifiés en 2000 et surtout en 2001, et se sont accompagnés de dégâts très importants et sans précédent connu. La nature et la dynamique d’apparition des symptômes observés suggéraient d’emblée qu’il s’agissait d’un phénomène inhabituel et apparemment distinct des dépérissements « classiques » du hêtre, bien que la possibilité d’interactions entre ces deux problèmes ne puisse être écartée a priori. L’ampleur de la zone géographique au sein de laquelle les symptômes se sont déclarés de manière relativement brusque et simultanée constitue également une caractéristique remarquable du phénomène observé. [less ▲]

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See detailWind Excitation and Severity of Standards Used for the Vibration Testing of Luminaires
Marin, Frederic ULg; Golinval, Jean-Claude ULg; Marville, Christian et al

Conference given outside the academic context (2003)

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