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See detailBelgique francophone. L'enfance de l'art
Delhalle, Nancy ULiege

in Ubu: scènes d'Europe = European stages (2010), 48/49

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See detailQuatre détails de la procédure en cassation devant le Conseil d'Etat à ne pas négliger
Donnay, Luc ULiege

in Liber amicorum Michel Melchior Liège, Strasbourg, Bruxelles : parcours des droits de l'homme (2010)

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See detailHeel effects on joint contact force components in the equine digit : a sensitivity analysis
Noble, Prisca ULiege; Lejeune, Jean-Philippe ULiege; Caudron, Isabelle ULiege et al

in Equine Veterinary Journal. Supplement (2010), 42

Reasons for performing study: Whereas the effect of heel configuration on the tension of the suspensory apparatus is well documented in the literature, there are few reports of joint contact force ... [more ▼]

Reasons for performing study: Whereas the effect of heel configuration on the tension of the suspensory apparatus is well documented in the literature, there are few reports of joint contact force components in the equine distal forelimb. Objectives: To improve understanding of the effect of heel configuration on equine digit joint loading, a sensitivity analysis was performed to compare the effect of a raised heel on joint contact force components in the coffin and fetlock joints during the stance phase of the trot. Materials and methods: FourWarmblood horses were used. An inverse dynamic analysis was carried out using kinematic and kinetic data. Taking into account the tendon wrapping forces (WF) around the sesamoid bones in the calculations, the joint contact forces (CF) were estimated for the coffin and fetlock joints during the trot stance phase (4 m/s). To test the sensitivity of the results to heel configuration changes, calculations were performed repeatedly for different heel configurations (raised by 0, 6 and 12°). A one-way ANOVA with repeated measures was used to test the effect of heel configuration (at the 3 levels) (a = 0.05; P<0.05; post hoc testing: Bonferroni). Results: For heel configurations raised from 0–12°: whereas the tension of the deep digital flexor tendon decreased and the tension of the superficial digital flexor tendon increased, for the coffin joint the peakWF(1.4 +- 0.25 bwt; 1.2 +- 0.2 bwt; 0.95 +- 0.1 bwt) and the peak CF (2.45 +- 0.25 bwt; 2.2 +- 0.2 bwt; 2 +- 0.1 bwt) decreased significantly (P<0.05). For the fetlock joint, the peak WF (3.8 +- 0.7 bwt; 4.1 +- 0.3 bwt; 4.4 0.25 bwt) and the peak CF (4.35 +- 0.7 bwt; 4.7 +- 0.35 bwt; 5 +- 0.3 bwt) increased, but not significantly. Conclusion: This analysis suggests that the coffin joint loading and fetlock joint loading are strongly connected. The heel configuration may influence both coffin joint and fetlock joint contact force components. [less ▲]

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See detailDe l'exercice de la démocratie dans les entreprises sociales
Rijpens, Julie ULiege; Mertens de Wilmars, Sybille ULiege

Article for general public (2010)

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See detailEffect of antiepileptic drugs and reactive oxygen species on folate receptor 1 (FOLR1)-dependent 5-methyltetrahydrofolate transport.
Opladen, Thomas; Blau, Nenad; RAMAEKERS, Vincent ULiege

in Molecular Genetics & Metabolism (2010), 101(1), 48-54

Metabolic breakdown of valproate (VPA), carbamazepine (CBZ) and phenytoin (PHT) by the cytochrome P450 pathway generates toxic drug intermediates and reactive oxygen species (ROS). This mechanism has been ... [more ▼]

Metabolic breakdown of valproate (VPA), carbamazepine (CBZ) and phenytoin (PHT) by the cytochrome P450 pathway generates toxic drug intermediates and reactive oxygen species (ROS). This mechanism has been suspected to play a role in the pathogenesis of secondary cerebral folate deficiency (CFD). Using KB-cell cultures, highly expressing the folate receptor 1 (FOLR1), the effect of antiepileptic drugs (AEDs) and reactive oxygen species (ROS) on the FOLR1 dependent 5-methyltetrahydrofolate (MTHF) uptake was studied. MTHF uptake is time and concentration dependent and shows saturation kinetics. At physiological MTHF concentrations the high-affinity FOLR1 represents the predominant mechanism for cellular incorporation, while at high MTHF concentrations other transport mechanisms participate in folate uptake. Exposure to PHT for more than 8h led to a higher MTHF uptake and decreased cell count, whereas MTHF uptake remained unaltered by VPA and CBZ. However, exposure to superoxide and hydrogen peroxide radicals significantly decreased cellular MTHF uptake. By specific elimination and downregulation of FOLR1 using phosphatidyl-inositol-specific phospholipase C (PIPLC) and siRNA silencing, it was shown that ROS not only inhibited FOLR1 mediated MTHF uptake but also affected all other mechanisms of membrane-mediated MTHF uptake. Generation of ROS with the use of AED might therefore provide an additional explanation for the disturbed folate transfer across the blood-CSF barrier in patients with CFD. [less ▲]

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See detailEukaryotic algae: where lies the diversity of oxygenic photosynthesis.
Cardol, Pierre ULiege; Franck, Fabrice ULiege

in Photosynthesis Research (2010), 106(1-2), 1-2

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See detailConcepts actuels de l'hyperaldostéronisme primaire
Vroonen, Laurent ULiege; Krzesinski, Jean-Marie ULiege; Hamoir, Etienne ULiege et al

in Revue Médicale de Liège (2010), 65(10), 583-587

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See detailElectrochromism: a useful probe to study algal photosynthesis.
Bailleul, Benjamin; Cardol, Pierre ULiege; Breyton, Cecile et al

in Photosynthesis Research (2010), 106(1-2), 179-89

In photosynthesis, electron transfer along the photosynthetic chain results in a vectorial transfer of protons from the stroma to the lumenal space of the thylakoids. This promotes the generation of an ... [more ▼]

In photosynthesis, electron transfer along the photosynthetic chain results in a vectorial transfer of protons from the stroma to the lumenal space of the thylakoids. This promotes the generation of an electrochemical proton gradient (Deltamu(H)(+)), which comprises a gradient of electric potential (DeltaPsi) and of proton concentration (DeltapH). The Deltamu(H)(+) has a central role in the photosynthetic process, providing the energy source for ATP synthesis. It is also involved in many regulatory mechanisms. The DeltapH modulates the rate of electron transfer and triggers deexcitation of excess energy within the light harvesting complexes. The DeltaPsi is required for metabolite and protein transport across the membranes. Its presence also induces a shift in the absorption spectra of some photosynthetic pigments, resulting in the so-called ElectroChromic Shift (ECS). In this review, we discuss the characteristic features of the ECS, and illustrate possible applications for the study of photosynthetic processes in vivo. [less ▲]

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See detailF1FO ATP synthase mutants in Chlamydomonas: Stability and oligomycin resistance mediated by atypical Asa7 protein; interaction between chloroplastic and mitochondrial bioenergetics
Lapaille, Marie ULiege; Escobar-Ramírez, Adelma; Degand, Hervé et al

in Biochimica et Biophysica Acta (BBA) - Bioenergetics (2010), 1797(Supplement 1), 29

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See detailModeling of InSAR displacements related with the January 2002 eruption of Nyiragongo volcano
Wauthier, Christelle ULiege; Cayol, Valérie; Kervyn, François et al

in ECGS Blue Books (2010)

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See detailGene expression and genetic analysis during higher plants embryogenesis
Abid, Ghassen ULiege; Jaquemin, Jean-Marie; Sassi, Khaled et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2010), 14(4), 667-680

This review describes and discusses recent attempts to analyze the embryogenesis process in higher plants, through combination of descriptive, experimental, and genetic approach. Analysis of gene ... [more ▼]

This review describes and discusses recent attempts to analyze the embryogenesis process in higher plants, through combination of descriptive, experimental, and genetic approach. Analysis of gene expression profiles has permitted to build hypothesis concerning the induced mechanisms in early phases of embryogenesis in higher plants. Such mechanisms involve specific transcriptional and post-transcriptional regulatory pathways as well as diverse signal transduction processes at each stage of plant development. [less ▲]

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See detailLEGAL CERTAINTY v LEGAL PRECISION. Some thoughts on comparative law
Gerkens, Jean-François ULiege

in Fundamina : A Journal of Legal History (2010), 16-1(2010), 121-129

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See detailEDUCATE State of the Art Academic Curricula and Conditions for Registration
Altomonte, Sergio; Attia, Shady ULiege; Herde, André et al

Report (2010)

The analysis and consolidation of the state of the art of environmental sustainability in higher education and in the conditions for accreditation and professional registration has constituted one of the ... [more ▼]

The analysis and consolidation of the state of the art of environmental sustainability in higher education and in the conditions for accreditation and professional registration has constituted one of the tasks of the 6-month long Work Package 2 - the first stage of development of EDUCATE - so as to build a comprehensive picture in terms of integration of environmental design and energy efficiency in current academic pedagogies and in the criteria that control access to the practice of architecture. [less ▲]

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See detailLa formation: un outil indispensable pour l'ingénieur
Courard, Luc ULiege; Michel, Frédéric ULiege

Article for general public (2010)

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See detailOrgan failure and tight glycemic control in the SPRINT study.
Chase, J Geoffrey; Pretty, Christopher G; Pfeifer, Leesa et al

in Critical Care (2010), 14(4), 154

INTRODUCTION: Intensive care unit mortality is strongly associated with organ failure rate and severity. The sequential organ failure assessment (SOFA) score is used to evaluate the impact of a successful ... [more ▼]

INTRODUCTION: Intensive care unit mortality is strongly associated with organ failure rate and severity. The sequential organ failure assessment (SOFA) score is used to evaluate the impact of a successful tight glycemic control (TGC) intervention (SPRINT) on organ failure, morbidity, and thus mortality. METHODS: A retrospective analysis of 371 patients (3,356 days) on SPRINT (August 2005 - April 2007) and 413 retrospective patients (3,211 days) from two years prior, matched by Acute Physiology and Chronic Health Evaluation (APACHE) III. SOFA is calculated daily for each patient. The effect of the SPRINT TGC intervention is assessed by comparing the percentage of patients with SOFA </=5 each day and its trends over time and cohort/group. Organ-failure free days (all SOFA components </=2) and number of organ failures (SOFA components >2) are also compared. Cumulative time in 4.0 to 7.0 mmol/L band (cTIB) was evaluated daily to link tightness and consistency of TGC (cTIB >/=0.5) to SOFA </=5 using conditional and joint probabilities. RESULTS: Admission and maximum SOFA scores were similar (P = 0.20; P = 0.76), with similar time to maximum (median: one day; IQR: 13 days; P = 0.99). Median length of stay was similar (4.1 days SPRINT and 3.8 days Pre-SPRINT; P = 0.94). The percentage of patients with SOFA </=5 is different over the first 14 days (P = 0.016), rising to approximately 75% for Pre-SPRINT and approximately 85% for SPRINT, with clear separation after two days. Organ-failure-free days were different (SPRINT = 41.6%; Pre-SPRINT = 36.5%; P < 0.0001) as were the percent of total possible organ failures (SPRINT = 16.0%; Pre-SPRINT = 19.0%; P < 0.0001). By Day 3 over 90% of SPRINT patients had cTIB >/=0.5 (37% Pre-SPRINT) reaching 100% by Day 7 (50% Pre-SPRINT). Conditional and joint probabilities indicate tighter, more consistent TGC under SPRINT (cTIB >/=0.5) increased the likelihood SOFA </=5. CONCLUSIONS: SPRINT TGC resolved organ failure faster, and for more patients, from similar admission and maximum SOFA scores, than conventional control. These reductions mirror the reduced mortality with SPRINT. The cTIB >/=0.5 metric provides a first benchmark linking TGC quality to organ failure. These results support other physiological and clinical results indicating the role tight, consistent TGC can play in reducing organ failure, morbidity and mortality, and should be validated on data from randomised trials. [less ▲]

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See detailConsolidation institutionnelle et démocratisation en RDC
Kabamba, Bob ULiege

in Revue de la Faculté de Droit de l'Université de Liège (2010)

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See detailGrupurile informale : primii pasi in actiunea colectiva
Teclu, Codrat Alin ULiege

in Lambru, Mihaela; Vamescu, Ancuta; Kivu, Mircea (Eds.) Romania 2010 : Sectorul neguvernamental - profil, tendinte, provocari (2010)

L'ouvrage se propose de dresser un portrait quantitatif et qualitatif du secteur non-gouvernemental roumain 10 ans après la dernière grande enquête sur le sujet. Les principaux défis des ONG sont ... [more ▼]

L'ouvrage se propose de dresser un portrait quantitatif et qualitatif du secteur non-gouvernemental roumain 10 ans après la dernière grande enquête sur le sujet. Les principaux défis des ONG sont également abordés. Notre contribution sur les groupes informels de citoyens se trouve en pp. 90-93. [less ▲]

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