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See detailCaractérisation micro-échelle du risque d’inondation : modélisation hydraulique détaillée et impacts socio-économiques
Ernst, Julien ULiege; Dewals, Benjamin ULiege; Detrembleur, Sylvain ULiege et al

in Risque d'Inondation en Ile de France, 100 ans après les crues de 1910 (2010, March)

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See detailUtilisation des prises de vue aérienne à basse altitude pour le suivi des activités hydro-agricoles. Cas du bassin du Kou.
Wellens, Joost ULiege; Diallo, M.; Dakouré, D. et al

in Integrated water resources management and challenges of the sustainable development (2010, March)

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See detailESR evidence of superoxide anion, hydroxyl radical and singlet oxygen generation during photosensitization of PPME in HCT-116 cells
Quoilin, Caroline ULiege; Guelluy, Pierre-Henri ULiege; Grammenos, Angeliki ULiege et al

Poster (2010, March)

Pyropheophorbide-a methyl ester (PPME), a derivative of chlorophyll a, is a second-generation photosensitizer and is studying largely in vitro for nearly a decade on cancerous cells. It has been ... [more ▼]

Pyropheophorbide-a methyl ester (PPME), a derivative of chlorophyll a, is a second-generation photosensitizer and is studying largely in vitro for nearly a decade on cancerous cells. It has been previously established on HCT-116 (human colon carcinoma cell line) that PPME is a molecule able to create apoptotic and necrotic death (Matroule et al). The cytotoxicity of PPME is presumed to be induced by reactive oxygen species (ROS) generated by the photoexcited molecule. Actually, to the best of our knowledge, no experimental evidence enables to confirm this supposition in an indubitable manner. Electron spin resonance (ESR) associated with spin trapping technique is a powerful method to detect, quantify and identify the ROS produced after photoactivation of PPME. Previous results indicate that PPME penetrates inside cells and localizes inside specific organelles (endothelial reticulum, Golgi apparatus and lysosome) (Matroule et al). The recent researches of Guelluy et al have also clearly demonstrated the presence of PPME inside mitochondrion. Consequently, ESR experiments were performed using an intracellular located spin trap, POBN (4-pyridyl 1-oxide-N-tert-butylnitrone), in order to detect in situ the ROS production. It has been shown that PPME is able to generate superoxide anions and hydroxyl radicals. Irradiation of the dye in HCT-116 cells in the presence of POBN spin trap and ethanol scavenger (2%, a non-toxic concentration) leads to the apparition of the ESR spectrum characteristics of POBN/ethoxy adduct. To assess the extent of contribution of ROS and to determine a possible reaction mechanism, competition experiments with specific quencher agents were carried out. Addition of catalase (CAT), a hydrogen peroxide quencher, or superoxide dismutase (SOD), a superoxide anion quencher, inhibits 30% of the signal. The parallel effect of SOD and CAT suggest that superoxide anion and hydrogen peroxide are involved in the generation of hydroxyl radicals via a Fenton reaction. This assertion is reinforced by the 20% reduction of signal intensity when adding desferroxamine, a Fe3+ chelator also implicated in Fenton reaction. Addition of DABCO, a quencher of singlet oxygen, to cells reduces 70% of the POBN/ethoxy adduct signal intensity. [less ▲]

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See detailThe lipoxygenase metabolic pathway in plants: potential for industrial production of natural green leaf volatiles
Gigot, Cédric ULiege; Ongena, Marc ULiege; Fauconnier, Marie-Laure ULiege et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2010), 14(3), 451-460

Lipoxygenase enzymatic pathway is a widely studied mechanism in the plant kingdom. Combined actions of three enzymes: lipase, lipoxygenase (LOX) and hydroperoxide lyase (HPL) convert lipidic substrates ... [more ▼]

Lipoxygenase enzymatic pathway is a widely studied mechanism in the plant kingdom. Combined actions of three enzymes: lipase, lipoxygenase (LOX) and hydroperoxide lyase (HPL) convert lipidic substrates such as C18:2 and C18:3 fatty acids into short chain volatiles. These reactions, triggered by cell membrane disruptions, produce compounds known as Green Leaf Volatiles (GLVs) which are C6 or C9-aldehydes and alcohols. These GLVs are commonly used as flavors to confer a fresh green odor of vegetable to food products. Therefore, competitive biocatalytic productions have been developed to meet the high demand in these natural flavors. Vegetable oils, chosen for their lipidic acid profile, are converted by soybean LOX and plant HPL into natural GLVs. However this second step of the bioconversion presents low yield due to the HPL instability and the inhibition by its substrate. This paper will shortly describe the different enzymes involved in this bioconversion with regards to their chemical and enzymatic properties. Biotechnological techniques to enhance their production potentialities will be discussed along with their implication in a complete bioprocess, from the lipid substrate to the corresponding aldehydic or alcoholic flavors. [less ▲]

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See detailPromouvoir des approches innovantes de recherche-développement en matière de GIRE au Burkina Faso
Wellens, Joost ULiege; Derouane, Johan

in Integrated water resources management and challenges of the sustainable development - Abstract volume (2010, March)

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See detailPromouvoir des approches innovantes de recherche-développement en matière de GIRE au Burkina Faso.
Wellens, J.; Diallo, M.; Gardin, N. et al

Conference (2010, March)

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See detailIntroduction to colorimetry
Embrechts, Jean-Jacques ULiege

Learning material (2010)

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See detailLes journées PROVAC-SPSE-CPMS de juin 2009
Giot, Catherine ULiege; Miermans, Marie-Christine ULiege; Swennen, Béatrice et al

in Promouvoir la santé à l'école (2010), (29), 3-4

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See detailQuel niveau d'étude en mathématiques ? Pour quel public d'élèves ou d'étudiants ?
Schneider-Gilot, Marguerite ULiege

Scientific conference (2010, March)

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See detailFaraday instability on a network
Delon, Giles ULiege; Terwagne, Denis ULiege; Adami, Nicolas ULiege et al

Poster (2010, March)

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See detailUn sculpteur wallon au service de l’Empire et de la Restauration : Henri-Joseph RUTXHIEL (Lierneux, 1775 – Paris, 1837)
Etienne, Mary ULiege

in Glain et Salm Haute Ardenne (2010), 64

Brève biographie sculpteur wallon (Lierneux, 1775 – Paris, 1837) - Carrière sous l'Empire et la Restauration - Portraitiste de la famille impériale et de la famille de Bourbon

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See detailAxially Loaded Stainless Steel Columns in Case of Fire
Lopes, Nuno; Vila Real, Paulo; Simões da Silva, Luís et al

in Journal of Structural Fire Engineering (2010), 1(1), 43-59

The simple model of Eurocode 3, for the fire resistance evaluation of stainless steel members, are based on the procedures used for carbon steel structural elements. However, due to the existing ... [more ▼]

The simple model of Eurocode 3, for the fire resistance evaluation of stainless steel members, are based on the procedures used for carbon steel structural elements. However, due to the existing differences in the constitutive laws of these two materials, it is expected that it would not be possible to use, in both materials, the same formulae for the member stability calculation, as proposed in Eurocode 3. This paper aims at increasing the knowledge on the behaviour of stainless steel axially loaded columns at elevated temperatures. For this purpose, a geometrical and material non linear computer code has been used to determine the buckling load of these elements. The Eurocode formulae are evaluated and a new proposal, that ensures accurate and conservative results when compared with the numerical simulations, is presented. [less ▲]

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See detailPEGASE, an integrated river/basin model dedicated to surface water quality assessment: application to cocaine
Deliège, Jean-François ULiege; Everbecq, Etienne ULiege; Magermans, Pol ULiege et al

in Acta Clinica Belgica (2010), 65(Supplement 1), 42-48

The Aquapôle of the University of Liège has been involved in environmental modeling for more than 20 years. Among other, its current R&D unit focuses on the compartment of surface water, and – for ... [more ▼]

The Aquapôle of the University of Liège has been involved in environmental modeling for more than 20 years. Among other, its current R&D unit focuses on the compartment of surface water, and – for modeling processes – is specialized on the water quality. One of its environmental models, called Pegase (Planification Et Gestion de l’ASsainissement des Eaux), French acronym for “Planning and management of water purification” is devoted to the modeling of the environmental state of surface water, at different scales from small watersheds (10 km²) and basins up to entire transnational Districts (more than 100.000 km²). The software is used operationally by several administrations (Agencies and Ministries) mainly through Europe (France and Benelux, Germany ...), and several calculations have also been performed at international District levels for international commissions (Scheldt, Meuse, Moselle ...) Recently, the Pegase model has been adapted to describe the cocaine’s behavior (using a stable metabolite of the cocaine in the environment: the benzoylecgonine) in waste water, waste water treatment plants (WWTP) and surface water. The cocaine is newly described in the model as an additional micropollutant (Pegase already treats numerous heavy metals), thanks to the implementation of new state variable equations and their specific parameterizations. At a first stage, only the urban sources (releases associated to the consumption by inhabitants) were considered as the industrial releases and the soil loads are assumed to be negligible. Simulations of benzoylecgonine have been done in the Walloon and Flemish regions, where many measurements from the COWAT project were available. These first results are showing a good agreement between calculated and measured values. This ability of the model to simulate the fate of the cocaine derivatives in surface waters should be continued and extended to other metabolites. [less ▲]

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See detailAkhénaton
Laboury, Dimitri ULiege

Book published by Pygmalion - Flammarion (2010)

Amenhotep IV, ninth Pharaoh of the 18th Dynasty (ca 1352 - 1335 B.C.), who changed his name into Akhenaten, is probably the most debated figure of Ancient Egyptian History. Known as the first founder of a ... [more ▼]

Amenhotep IV, ninth Pharaoh of the 18th Dynasty (ca 1352 - 1335 B.C.), who changed his name into Akhenaten, is probably the most debated figure of Ancient Egyptian History. Known as the first founder of a monotheistic religion in the history of mankind, he holds an exceptional position in modern collective memories about Ancient Egypt, despite the fact that he was rejected into oblivion by his direct successors. His modern fame is fundamentally due to the reappropriation of his character by various and incredibly numerous occidental or contemporary ideologies. In this context of highly culturo-centric reinterpretation, it is often very difficult, for the layman or the laywoman as well as for the scholar, to comprehend the king who actually ruled Egypt in the middle of the 14th century B.C. The book attempts to address this issue by proposing an archaeological biography of Akhenaton, i.e. a description of the historical facts of his reign that are physically - or archaeologically - attested, with the constant aim of distinguishing these facts from their interpretations. Such an approach allows the reader to understand how egyptological knowledge is constructed. The book is structured according to the different phases of the actual life of Akhenaten: after a necessary appraisal of his modern rediscovery and reinterpretations, a chapter is respectively devoted to his childhood and the Egyptian Empire in which he grew up, to the first years of his reign, to the invention of real Atenism, in year 4, to the king’s project when he moved his capital to Akhet-Aten - Amarna, in Middle Egypt, and, at last, to his post-mortem survival, in the reactions of his successors and followers. The book ends with some conclusions about the epistemological capabilities of archaeological biography and about the particularity of Akhenaten and his Atenist ideology. [less ▲]

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See detailLa vignette thérapeutique de l'étudiant: la maladie d'Alzheimer
Jedidi, Haroun ULiege; JEDIDI, Zayd ULiege; Salmon, Eric ULiege

in Revue Médicale de Liège (2010), (65(3)), 163-168

Alzheimer's disease is the most common neurodegenerative disease encountered in patients over 60 years. By its prevalence and the consequent individual and social loss of function Alzheimer's disease is a ... [more ▼]

Alzheimer's disease is the most common neurodegenerative disease encountered in patients over 60 years. By its prevalence and the consequent individual and social loss of function Alzheimer's disease is a major public health problem. With the presentation of a clinical story of Alzheimer's disease in an elderly patient, we propose a diagnostic and therapeutic discussion on this clinical problem. We must adjust the treatment for each patient and overall not omit the non pharmacological therapeutic approaches. [less ▲]

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See detailL'essentiel c'est de...participer
Pirotte, Gautier ULiege

Learning material (2010)

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See detailContraception orale pour les kystes ovariens fonctionnels?
Belche, Jean ULiege

in Minerva: Tijdschrift Voor Evidence Based Medicine (2010), 9(3), 30-31

Cette synthèse méthodique des RCTs évaluant l’intérêt d’un traitement contraceptif oral pour traiter un kyste fonctionnel de l’ovaire chez une femme en âge de procréer montre la faible qualité ... [more ▼]

Cette synthèse méthodique des RCTs évaluant l’intérêt d’un traitement contraceptif oral pour traiter un kyste fonctionnel de l’ovaire chez une femme en âge de procréer montre la faible qualité méthodologique des trop rares études originales et l’absence de preuve de l’intérêt d’un tel traitement pour une affection à résolution très fréquemment spontanée. [less ▲]

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See detailRisk Analysis in F&V SectorCOLEACP-PIP Approach & Facts
Schiffers, Bruno ULiege

Scientific conference (2010, March)

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