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See detailCompte rendu de : Christian Nicolas: Sic enim appello... Essai sur l’autonymie terminologique gréco-latine chez Cicéron
Rochette, Bruno ULg

in Gnomon : Kritische Zeitschrift für die Gesamte Klassische Altertumswissenschaft (2008), 80

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See detailRole of TGF-beta1-independent changes in protein neosynthesis, p38alphaMAPK, and cdc42 in hydrogen peroxide-induced senescence-like morphogenesis.
Chretien, Aline; Dierick, Jean-Francois; Delaive, Edouard et al

in Free Radical Biology & Medicine (2008), 44(9), 1732-51

The role of TGF-beta1 in hydrogen peroxide-induced senescence-like morphogenesis has been described. The aim of this work was to investigate whether TGF-beta1-independent changes in protein synthesis are ... [more ▼]

The role of TGF-beta1 in hydrogen peroxide-induced senescence-like morphogenesis has been described. The aim of this work was to investigate whether TGF-beta1-independent changes in protein synthesis are involved in this morphogenesis and to study possible mechanisms occurring earlier than TGF-beta1 overexpression. Among the multiple TGF-beta1-independent changes in protein neosynthesis, followed or not by posttranslational modifications, identified by proteomic analysis herein, those of ezrin, L-caldesmon, and HSP27 were particularly studied. Rho-GTPase cdc42 was shown to be responsible for p38(MAPK) activation, in turn triggering phosphorylation of L-caldesmon and HSP27. Cdc42 was also shown to be mainly responsible for the increase in TGF-beta1 mRNA level observed at 24 h after treatment with H(2)O(2) and onward. This study further clarified the mechanisms of senescence-like morphogenesis in addition to the previously demonstrated role of TGF-beta1 signaling pathways. [less ▲]

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See detailcompte rendu de : Raimund SCHULZ Die Antike und das Meer
Rochette, Bruno ULg

in Latomus : Revue d'Etudes Latines (2008)

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See detailcompte rendu de : Giuseppe Flammini (ed.), Hermeneumata Pseudodositheana Leidensia
Rochette, Bruno ULg

in Byzantinische Zeitschrift (2008), 98(2), 585-590

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See detailModern look at a pathology of the millenium : abdominal aortic aneurysms.
Limet, Raymond ULg; Sakalihasan, Natzi ULg

in Bulletins et Mémoires de l’Académie Royale de Médecine de Belgique (2008), 163(5), 205-11

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See detailFunctional imaging of abdominal aortic aneurysms
Sakalihasan, Natzi ULg; Hustinx, Roland ULg; Gomez, Pierre et al

in Aortic Aneurysms, new insights of an old problem (2008)

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See detailprésentation de la réimpression de : Roersch-Thomas-Hombert, Eléments de grammaire grecque
Rochette, Bruno ULg

in Bulletin de la Fédération des Professeurs de Grec et de Latin (2008), 163(janvier-février),

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See detailEvidence of a highly complex phylogeographic structure on a specialist river bird species, the dipper (Cinclus cinclus).
Hourlay, F.; Libois, Roland ULg; D'Amico, F. et al

in Molecular Phylogenetics & Evolution (2008), 49(2), 435-44

This study details the phylogeographic pattern of the white-throated dipper (Cinclus cinclus), a Palearctic, temperate, passerine bird that is exclusively associated with flowing water. Our results reveal ... [more ▼]

This study details the phylogeographic pattern of the white-throated dipper (Cinclus cinclus), a Palearctic, temperate, passerine bird that is exclusively associated with flowing water. Our results reveal a complex phylogeographic structure with at least five distinct lineages for the Western Palearctic region. As for many species of the Western Palearctic fauna and flora, this genetic structure is probably linked to the isolation of populations in different southern refuges during glacial periods. Furthermore, the isolation of populations in Scandinavia and/or Eastern regions, but also in Morocco and probably in Corsica, was accentuated by ecological and biogeographic barriers during Quaternary interglacial periods. During glacial periods, Italy, Sicily and the Balkano-Carpathian region acted as major refuge zones for the dipper. At the end of the last ice age, Western Europe was repopulated by dippers from an Italian refuge, while Eastern Europe was recolonised by Balkano-Carpathian birds. A large contact zone between these two lineages was evidenced and extends from Luxembourg to Hungary. Finally, our results indicate the need to clarify the taxonomic status of the dipper, especially concerning the European subspecies whose validity appears uncertain. [less ▲]

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See detailLa sociologie de l'action publique
Levêque, Audrey ULg

in Jacquemain, Marc; Frère, Bruno (Eds.) Epistémologie de la sociologie. Paradigmes pour le XXIè siècle. (2008)

Introduction à la sociologie de l'action publique, cette contribution retrace les grandes lignes de la naissance, de la définition et des étapes de l'analyse des politiques publiques ainsi que son ... [more ▼]

Introduction à la sociologie de l'action publique, cette contribution retrace les grandes lignes de la naissance, de la définition et des étapes de l'analyse des politiques publiques ainsi que son évolution vers l'action publique. [less ▲]

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See detailG_CUBE: un logiciel simple pour le cubage des arbres et des peuplements forestiers
Lejeune, Philippe ULg; Hebert, Jacques ULg; Rondeux, Jacques ULg

in Silva Belgica (2008), 115(2), 16-18

G_Cube est un logiciel de cubage d'arbres sur pied ou abattus fonctionnant dans l'environnement Microsoft® Excel. Il donne accès aux principaux barèmes de cubage (défilement, décroissance), ainsi qu'aux ... [more ▼]

G_Cube est un logiciel de cubage d'arbres sur pied ou abattus fonctionnant dans l'environnement Microsoft® Excel. Il donne accès aux principaux barèmes de cubage (défilement, décroissance), ainsi qu'aux équations de cubage adaptées à la Région wallonne. Il permet également de procéder à une estimation de la valeur des lots et intègre un module simplifié de traitement de données d'inventaire par échantillonnage. [less ▲]

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See detailSimplifying strong electronic correlations in uranium: Localized uranium heavy-fermion UM(2)Zn(20) (M = Co, Rh) compounds
Bauer, E. D.; Wang, C.; Fanelli, V. R. et al

in Physical Review. B : Condensed Matter (2008), 78(11),

The physical properties including magnetic susceptibility, magnetization, specific heat, and dynamic susceptibility chi ''(E) are reported for single crystals of the cubic UM(2)Zn(20) (M = Co, Rh ... [more ▼]

The physical properties including magnetic susceptibility, magnetization, specific heat, and dynamic susceptibility chi ''(E) are reported for single crystals of the cubic UM(2)Zn(20) (M = Co, Rh) materials. Maxima in the thermodynamic data at T(max) similar to 10 K for both compounds and a broad peak in chi ''(E) at 5 K in UCo(2)Zn(20) of width Gamma=5 meV indicate a heavy-fermion state characterized by a Kondo temperature T(K) similar to 20-30 K arising from weak hybridization of f- and conduction-electron states. Anderson impurity model fits to the data in the Kondo limit including crystalline electric-field effects corroborate an ionic-like uranium electronic configuration in UM(2)Zn(20). [less ▲]

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See detailEffect of temperature increase on the courtship behavior and the fitness in the Palmate newt
Galloy, Valérie ULg; Lo Presti, Wendy; Denoël, Mathieu ULg

Poster (2008)

A trend in global warming is now undeniable. Increases of global temperatures have resulted in measurable shifts in the distribution, phenology and survival of some plant and animal species. However, the ... [more ▼]

A trend in global warming is now undeniable. Increases of global temperatures have resulted in measurable shifts in the distribution, phenology and survival of some plant and animal species. However, the mechanisms showing the link between global warming and declines remain unclear. The aim of this study was to examine whether courtship displays and fitness could be affected by a temperature increase. To this end, we compared the sexual behavior and egg-laying traits at naturally occurring temperatures (14 C, 18 C and 22 C) in palmate newts (Triturus helveticus). First, our results underline the importance of female role in the male courtships. The majority of male behaviors are affected by the female responsiveness, which is temperature dependent. They also show that water temperature increase has a negative effect on the fecundity of female newts. Females lay half as many eggs at high temperatures as they do at low temperatures and of these only one third hatch. The demonstration of such a detrimental effect shows that more experimental studies are required to understand the proximate mechanisms of global warming. [less ▲]

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See detailStatus and causes of decline in heterochronic newts from Europe
Denoël, Mathieu ULg; Dzukic, Georg; Ficetola, Gentile et al

Conference (2008)

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See detailReverse and Conventional Chemical Ecology Approaches for the Development of Oviposition Attractants for Culex Mosquitoes
Leal, Walter S.; Barbosa, Rosângela M. R.; Xu, Wei et al

in PLoS ONE (2008), 3

Synthetic mosquito oviposition attractants are sorely needed for surveillance and control programs for Culex species, which are major vectors of pathogens causing various human diseases, including ... [more ▼]

Synthetic mosquito oviposition attractants are sorely needed for surveillance and control programs for Culex species, which are major vectors of pathogens causing various human diseases, including filariasis, encephalitis, and West Nile encephalomyelitis. We employed novel and conventional chemical ecology approaches to identify potential attractants, which were demonstrated in field tests to be effective for monitoring populations of Cx. p. quinquefasciatus in human dwellings. Immunohistochemistry studies showed that an odorant-binding protein from this species, CquiOBP1, is expressed in trichoid sensilla on the antennae, including short, sharp-tipped trichoid sensilla type, which house an olfactory receptor neuron sensitive to a previously identified mosquito oviposition pheromone (MOP), 6-acetoxy-5-hexadecanolide. CquiOBP1 exists in monomeric and dimeric forms. Monomeric CquiOBP1 bound MOP in a pH-dependent manner, with a change in secondary structure apparently related to the loss of binding at low pH. The pheromone antipode showed higher affinity than the natural stereoisomer. By using both CquiOBP1 as a molecular target in binding assays and gas chromatography-electroantennographic detection (GC-EAD), we identified nonanal, trimethylamine (TMA), and skatole as test compounds. Extensive field evaluations in Recife, Brazil, a region with high populations of Cx. p. quinquefasciatus, showed that a combination of TMA (0.9 µg/l) and nonanal (0.15 ng/µl) is equivalent in attraction to the currently used infusion-based lure, and superior in that the offensive smell of infusions was eliminated in the newly developed synthetic mixture. [less ▲]

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See detailGene expression profiling of hypothalamic hamartomas: a search for genes associated with central precocious puberty
Parent, Anne-Simone ULg; Matagne, Valérie; Westphal, Manfred et al

in Hormone Research (2008), 69

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See detailRecent discoveries of new hantaviruses widen their range and question their origins.
Henttonen, Heikki; Buchy, Philippe; Suputtamongkol, Yupin et al

in Annals of the New York Academy of Sciences (2008), 1149

Hantaviruses belong to the Bunyaviridae family. While usually hosted by wild mammals, they are potentially pathogenic for humans, and several serologically distinct groups associated with different ... [more ▼]

Hantaviruses belong to the Bunyaviridae family. While usually hosted by wild mammals, they are potentially pathogenic for humans, and several serologically distinct groups associated with different syndromes have been identified. Yet, investigations have mostly been conducted where human infections by hantaviruses constitute a real and well-identified public health problem, i.e., the holarctic and neotropical areas. Some hantaviruses have also been described from a Suncus murinus in India and a Bandicota indica in Thailand. In addition, recent investigations in Cambodia revealed new Hantavirus types. More recently, two new Hantavirus species were described: Sangassou from a Hylomyscus simus, and Tanganya from a Crocidura theresae, both from Africa (Guinea), thus strongly questioning the current views about geographic range, evolution, and epidemiology of hantaviruses. In such a framework, we have conducted a survey of Hantavirus diversity in Southeast Asia which allows us to isolate the Thailand virus and address questions about the taxonomy of their rodent hosts. Here we present a molecular analysis of representatives of all currently known Hantavirus species, thus allowing the comparison between the newly described ones with a large range sample of rodent hantaviruses. Our results clearly point to the presence of a particular lineage of hantaviruses in Southeast Asia. It also strongly suggests that new viruses, additional mammalian hosts and different related syndromes in humans are likely to be discovered in the near future, particularly in Southeast Asia and in Africa, where Muridae rodents are highly diversified. Furthermore, additional work is also urgently needed to investigate the hantaviruses associated with Crociduridae and Soricidae. [less ▲]

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See detail2-Aminopropane-1,2,3-tricarboxylic acid: Synthesis and co-crystallization with the class A beta-lactamase BS3 of Bacillus licheniformis.
Beck, Josephine; Sauvage, Eric ULg; Charlier, Paulette ULg et al

in Bioorganic & Medicinal Chemistry Letters (2008), 18(13), 3764-8

The title compound 4 has been prepared in four steps from ethylglycinate in 63% overall yield. This amino analog of citric acid has been co-crystallized with the class A beta-lactamase BS3 of Bacillus ... [more ▼]

The title compound 4 has been prepared in four steps from ethylglycinate in 63% overall yield. This amino analog of citric acid has been co-crystallized with the class A beta-lactamase BS3 of Bacillus licheniformis and the structure of the complex fully analyzed by X-ray diffraction. Tris-ethyl aminocitrate 3 and the free tris-acid 4 have been tested against a member beta-lactamase from all distinct subgroups. They are novel inhibitors of class A beta-lactamases, still modest but more potent than citrate and isocitrate. [less ▲]

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