Publications ORBi OA
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See detailRhoA-GDP regulates RhoB protein stability. Potential involvement of RhoGDIalpha.
Ho, Thi Thanh Giang ULg; Merajver, Sofia D; Lapière, Charles et al

in Journal of Biological Chemistry (2008), 283(31), 21588-98

RhoA plays a significant role in actin stress fibers formation. However, silencing RhoA alone or RhoA and RhoC did not completely suppress the stress fibers suggesting a residual "Rho-like" activity. RhoB ... [more ▼]

RhoA plays a significant role in actin stress fibers formation. However, silencing RhoA alone or RhoA and RhoC did not completely suppress the stress fibers suggesting a residual "Rho-like" activity. RhoB, the third member of the Rho subclass, is a shortlived protein barely detectable in basal conditions. In various cell types, the silencing of RhoA induced a strong up-regulation of both total and active RhoB protein levels that were rescued by re-expressing RhoA and related to an enhanced half-life of the protein. The RhoA-dependent regulation of RhoB does not depend on the activity of RhoA but is mediated by its GDP-bound form. The stabilization of RhoB was not dependent on isoprenoid biosynthesis, Rho kinase, extracellular signal-regulated kinase, p38 mitogen-activated kinase, or phosphatidylinositol 3'-OH kinase pathways but required RhoGDIalpha. The forced expression of RhoGDIalpha increased RhoB half-life, whereas its knock-down antagonized the induction of RhoB following RhoA silencing. Moreover, a RhoA mutant (RhoAR68E) unable to bind RhoGDIalpha was significantly less efficient as compared with wild-type RhoA in reversing RhoB up-regulation upon RhoA silencing. These results suggest that, in basal conditions, RhoGDIalpha is rate-limiting and the suppression of RhoA makes it available to stabilize RhoB. Our results highlight RhoGDIalpha-dependent cross-talks that regulate the stability of RhoGTPases. [less ▲]

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See detailAccompagner les enseignants dans l'analyse des traces d'apprentissage de leurs apprenants : le pari d'une formation continue et située, visant la professionnalisation.
Georges, François ULg; Poumay, Marianne ULg

in Charnet, Chantal; Ghersi, Claire; Monimo, Jean-Louis (Eds.) Le défi de la qualité de l'enseignement supérieur : vers un changement de paradigme ... (2008)

En 2006, le Laboratoire de Soutien à l’Enseignement Télématique (LabSET) accompagné de la Haute Ecole Mosane d’Enseignement Supérieur (HEMES) s’est lancé dans la conception d’un outil en ligne destiné à ... [more ▼]

En 2006, le Laboratoire de Soutien à l’Enseignement Télématique (LabSET) accompagné de la Haute Ecole Mosane d’Enseignement Supérieur (HEMES) s’est lancé dans la conception d’un outil en ligne destiné à soutenir l’apprentissage des compétences de lecture et d’écriture en français.Le présent article décrit l’outil, parcourt les concepts pédagogiques qui ont présidé à sa conception, fait état des premiers usages et propose des pistes d’action de formation des enseignant en vue d’optimiser l’usage de cet outil. [less ▲]

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See detailLes compétences, des objectifs particuliers.
Beckers, Jacqueline ULg; Leclercq, Dieudonné ULg; Poumay, Marianne ULg

Learning material (2008)

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See detailLa rehabilitation pulmonaire dans la bronchopneumopathie chronique obstructive.
Corhay, Jean-Louis ULg; Nguyen Dang, Delphine ULg; Schees, Pierre ULg et al

in Revue Médicale de Liège (2008), 63(11), 677-83

The current treatment of chronic obstructive pulmonary disease (COPD) patients must comprise, in addition to an optimal pharmacological treatment, a pulmonary rehabilitation, if possible multidisciplinary ... [more ▼]

The current treatment of chronic obstructive pulmonary disease (COPD) patients must comprise, in addition to an optimal pharmacological treatment, a pulmonary rehabilitation, if possible multidisciplinary, and a program of post-rehabilitation in order to maintain the outcomes. Today pulmonary rehabilitation has proved to be effective in improving dyspnoea, exercise capacity and quality of life in COPD patients, and reducing the use of health services and thus the cost. In this article we want to present pulmonary rehabilitation, its indications and results, and the way by which it is held in the CHU of Liege. [less ▲]

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See detailLe mesotheliome: un cancer professionnel encore d'actualite!
Corhay, Jean-Louis ULg; Duysinx, Bernard ULg; Louis, Renaud ULg

in Revue Médicale de Liège (2008), 63(3), 128-35

Mesothelioma is a rare tumour, particularly aggressive, whose incidence increases because of the massive use of asbestos during the last century. Asbestos remains indeed the principal etiologic agent of ... [more ▼]

Mesothelioma is a rare tumour, particularly aggressive, whose incidence increases because of the massive use of asbestos during the last century. Asbestos remains indeed the principal etiologic agent of this cancer. In the event of mesothelioma it is advisable to seek an exposure, even of short duration, often which dates back to several decades. In certain circumstances compensation can be obtained at the Occupational Diseases Found. The renewed interest with regard to this tumour is supported by the improvement of mesothelioma management, the new imaging techniques, the new treatments and the broad diffusion of information related to the risk of developing this tumour following asbestos inhalation. [less ▲]

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See detailPsychologie Educationnelle de l'Adolescent et du Jeune Adulte
Leclercq, Dieudonné ULg

Learning material (2008)

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See detailElektraRed, NetVocList et LinguaProLio : 3 recettes de vitamines pour dynamiser la langue
Thiry, Bernard ULg

in Les Cahiers de la Recherche en UER-Langues de HEC-ULg (2008), 2

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See detailCurie temperature, exchange integrals, and magneto-optical properties in off-stoichiometric bismuth iron garnet epitaxial films
Vertruyen, Bénédicte ULg; Cloots, Rudi ULg; Abell, J. S. et al

in Physical Review b (2008), 78(9), 094429

We have studied the influence of the stoichiometry on the structural, magnetic, and magneto-optical properties of bismuth iron garnet (Bi3Fe5O12) thin films grown by pulsed laser deposition. Films with ... [more ▼]

We have studied the influence of the stoichiometry on the structural, magnetic, and magneto-optical properties of bismuth iron garnet (Bi3Fe5O12) thin films grown by pulsed laser deposition. Films with different stoichiometries have been obtained by varying the Bi/Fe ratio of the target and the oxygen pressure during deposition. Stoichiometry variations influence the Curie temperature T-C by tuning the (Fe)-O-[Fe] geometry: TC increases when the lattice parameter decreases, contrary to what happens in the case of stoichiometric rare-earth iron garnets. The thermal variation of the magnetization, the Faraday rotation, and the Faraday ellipticity have been analyzed in the frame of the Neel two-sublattice magnetization model giving energies of -48 K (4.1 meV), -29 K (2.5 meV), and 84 K (7.3 meV) for the three magnetic exchange integrals j(aa), j(dd), and j(ad), respectively. Magneto-optical spectroscopy linked to compositional analysis by Rutherford backscattering spectroscopy shows that Bi and/or Fe deficiencies also affect the spectral variation (between 1.77 and 3.1 eV). Our results suggest that bismuth deficiency has an effect on the magneto-optical response of the tetrahedral Fe sublattice, whereas small iron deficiencies affect predominantly the magneto-optical response of the octahedral sublattice. [less ▲]

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See detailNeutron diffraction texture analysis and thermoelectric properties of BiCaCoO misfit compounds
Guilmeau, E.; Pollet, M.; Grebille, D. et al

in Materials Research Bulletin (2008), 43(2), 394-400

Sintered, textured and single crystal products of the layered misfit [Bi0.81CaO2](2)[CoO2](1.69) cobaltite have been successfully synthesized and characterized. Based on structure and texture models, the ... [more ▼]

Sintered, textured and single crystal products of the layered misfit [Bi0.81CaO2](2)[CoO2](1.69) cobaltite have been successfully synthesized and characterized. Based on structure and texture models, the orientation distribution of the hot-forged sample was successfully analysed by neutron diffraction. The results gave a clear description of the fiber texture with c-axes of the plate-like grains aligned parallel to the hot-forging direction. In terms of transport properties, the decrease of the electrical resistivity according to the degree of alignment and crystallinity of the materials evidenced the important role of the texturation and the strong anisotropy existing in these misfit layered cobaltites. (c) 2007 Elsevier Ltd. All rights reserved. [less ▲]

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See detailLes associations en Belgique. Une analyse quantitative et qualitative du secteur - Edition 2008
Marée, Michel ULg; Rijpens, Julie ULg; Gijselinckx, Caroline et al

Book (2008)

This publication is a direct follow-up to and an update of the previous publication on organizations in Belgium that appeared at the end of 2005. The aim is to provide the general public with a dynamic ... [more ▼]

This publication is a direct follow-up to and an update of the previous publication on organizations in Belgium that appeared at the end of 2005. The aim is to provide the general public with a dynamic description of the non-profit sector (associations) in Belgium via a quantitative and a qualitative analysis on the basis of the most recent data, while comparing it to previous data. A quantitative analysis of the sector has been made under three headings. The first chapter “The satellite account of the NPI” takes up and comments on the principal figures from the statistics generated by the National Bank with regards to what is known as “non-profit institutions”(NPI),associations and foundations. Production, contribution to the added value of the country, principal financial sources, covered costs,... form the main topics that are focussed on. The evolution of the sector over the period 2000 – 2004 is also outlined. The second chapter, “Employment in non-profit organizations”, focuses on the work factor in the nonprofit organizations that, in terms of salaried employment, represent the bulk of employment in the NPI’s. The third chapter, “Foundations in Belgium” focuses on the sector of the foundations that serve a public non-profit goal (the foundations beneficial to the public and the private foundations from which one can suppose that they serve a non-profit objective that goes beyond the pure private character). Strictly speaking, foundations are not associations, and yet they do have a number of things in common. They do not have a profit motive. Via their financing, they contribute in a broad sense to the dynamism of the sector and of civilian society. Chapter 3 paints a picture of this relatively unknown type of NPI that together do employ a few thousand people and pay out considerable sums of money. Chapter four, “The barometer of the civil society organizations in Belgium in the year 2007” forms the qualitative part of this study. It presents the results of a study that was carried out of 473 civil society organizations in 2007. The aim of the barometer is to get to know the points of view and experiences of the civil society organizations in the field covering a range of subjects: the recent introduction of the new laws concerning non-profit organizations and voluntary work and the evolution in the area of employment, volunteer work, members, sources of income,… Where in 2005 the barometer study was limited to the questioning of umbrella civil society organizations and federations of organizations, the study dug deeper to the level of local organizations, in such a way that will allow this barometer research to be repeated on a regular basis at a later date. [less ▲]

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See detailLa gouvernance en associations : pour une vision dynamique du CA
Mertens de Wilmars, Sybille ULg; Rijpens, Julie ULg

in Dossiers d'ASBL Actualités (Les) (2008), 108(108),

Depuis des décennies, la littérature scientifique en sciences de gestion identifie les différents rôles traditionnellement dévolus aux conseils d'administration des associations. Si la clarté dans la ... [more ▼]

Depuis des décennies, la littérature scientifique en sciences de gestion identifie les différents rôles traditionnellement dévolus aux conseils d'administration des associations. Si la clarté dans la définition des rôles respectifs semble évidemment souhaitable, elle n'implique pas pour autant que la répartition des rôles s'opère de manière identique et immuable dans chaque association. Au contraire, de récents travaux de recherche soulignent combien des éléments internes ou des facteurs externes à l'association influencent l'ordonnancement des différents rôles. Le modèle que nous présentons ici sous-tend la vision dynamique d'un conseil d'administration associatif [less ▲]

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See detailFondements d’une approche européenne de l'entreprise sociale
Mertens de Wilmars, Sybille ULg; Defourny, Jacques ULg

in Cahier de Recherche / Working papers de HEC Ecole de Gestion de l'Université de Liège (2008)

Alors que pratiquement personne ne s'y référait il y a encore une quinzaine d'années, la notion d'entreprise sociale est en train d'opérer une étonnante percée des deux côtés de l'Atlantique. Avant d ... [more ▼]

Alors que pratiquement personne ne s'y référait il y a encore une quinzaine d'années, la notion d'entreprise sociale est en train d'opérer une étonnante percée des deux côtés de l'Atlantique. Avant d'aborder l'émergence du concept d'entreprise sociale, nous rappelons d'abord brièvement les principales approches qui, depuis un quart de siècle, ont été développées pour saisir les réalités du troisième secteur (1). Nous essayons ensuite de voir dans quelle mesure, au sein de ce dernier, on peut identifier un nouvel entreprenariat social (2) et comment, en Europe, on l'a appréhendé sur le plan conceptuel (3). Ensuite, nous présentons les premiers développements théoriques qu'a favorisé l'émergence de ce nouveau concept (4). Enfin, nous montrons comment on peut enrichir la démarche européenne en la faisant entrer en dialogue avec les récentes évolutions observées sur la scène nord-américaine (5). [less ▲]

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See detailTitres-services : Régulation quasi-marchande et performances comparées des entreprises prestataires
Henry, Arnaud ULg; Defourny, Jacques ULg; Nassaut, S. et al

in Revue Belge de Sécurité Sociale (2008), 2

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See detailA randomized multicenter study of optimal circadian time of vinorelbine combined with chronomodulated 5-fluorouracil in pretreated metastatic breast cancer patients : eortc trial 05971
Coudert, Bruno; Focan, Christian; Genet, Dominique et al

in Chronobiology International (2008), 25

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See detailLa gestion des ressources humaines en économie sociale
Davister, Catherine ULg

in Regards sur le Travail - Ministère du Travail de Québec (2008), 5(1),

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See detailSocial Enterprise in Europe : Recent Trends and Developments
Defourny, Jacques ULg; Nyssens, Marthe

in Social Enterprise Journal (2008), 4(3),

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See detailRecommendations on how to Support Social Enterprises
Borzaga, Carlo; Defourny, Jacques ULg; Galera, Giulia et al

in EMES European Research Network, Social Enterprise: A New Model for Poverty Reduction and Employment Generation United Nations Development Programme (2008)

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See detailImages and Concepts of the Third Sector in Europe
Defourny, Jacques ULg; Pestoff, Victor

in EMES Working Papers (2008), 08(02),

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See detailAssociation et production de services
Mertens de Wilmars, Sybille ULg

in Dossier ASBL Actualités (2008)

Cet article vise à comprendre dans quelles situations les associations disposent d'un avantage institutionnel sur les autres types de producteurs (privés et publics) et à identifier sur quelles ... [more ▼]

Cet article vise à comprendre dans quelles situations les associations disposent d'un avantage institutionnel sur les autres types de producteurs (privés et publics) et à identifier sur quelles caractéristiques propres aux associations se basent leurs avantages. Une première section décrit certains échecs du marché, c'est-à-dire certaines circonstances dans lesquelles les entreprises for-profit ne semblent pas être les mieux placées pour assurer la production des biens ou services. Une deuxième section présente l'action publique pour pallier ces limites et identifie ses faiblesses. Après ces deux détours nécessaires, nous relevons, dans une troisième section, en quoi, selon le courant nord-américain des théories NPOs, les associations présentent des atouts particuliers pour dépasser les limites du marché et de l'Etat. On y relève également les désavantages inhérents à leur action. Enfin, une dernière section synthétise les différents arguments présentés en expliquant pourquoi, dans le contexte belge, les associations constituent un secteur productif important, présent dans de nombreuses branches d'activité, le plus souvent aux côtés de prestataires publics ou for-profit. [less ▲]

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