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See detailGender issues in the Coastal Sandy Zone of Thua Thien Hue Province
Nguyen Dang, Hao; Lebailly, Philippe ULg; Pham Khanh, Tu

in Improving food crop productivity in the coastal sandy area of the Thua Thien Hue Province Central Vietnam : Vietnam-Belgium interuniversity project 2004-2009 (2009)

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See detailDiversité des lombriciens dans les sols de la zone cotière sableuse de la province de Thua Thien Hue (Viet Nam)
Zirbes, Lara ULg; Collin, Caroline; Dufey, Joseph E. et al

in Improving food crop productivity in the coastal sandy area of the Thua Thien Hue Province Central Vietnam : Vietnam-Belgium interuniversity project 2004-2009 (2009)

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See detailA frozen heart.
DAVIN, Laurent ULg; Legrand, Victor ULg; Legrand, Delphine

in European heart journal (2009), 30(15), 1827

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See detailDrug-eluting stents: a study of international practice.
Austin, David; Oldroyd, Keith G.; Holmes, David R. Jr et al

in American heart journal (2009), 158(4), 576-84

OBJECTIVE: We aimed to analyze trends in drug-eluting stents (DES) use in four international health care and regulatory settings. BACKGROUND: Accounts suggest a differential approach to DES ... [more ▼]

OBJECTIVE: We aimed to analyze trends in drug-eluting stents (DES) use in four international health care and regulatory settings. BACKGROUND: Accounts suggest a differential approach to DES internationally and recent reductions in use following reports of late stent thrombosis. Current studies of clinical practice are limited in their scope. METHODS: Data were pooled from angioplasty registries in Alberta (Canada), Belgium, Mayo Clinic (Rochester, MN), and Scotland (UK) that have routinely recorded consecutive patients treated since 2003. Trend analysis was performed to examine variations in DES use over time and by clinical subgroup. RESULTS: A total of 178,504 lesions treated between January 2003 and September 2007 were included. In the Mayo Clinic Registry, rapid adoption to a peak of 91% DES use for all lesions by late 2004 was observed. In contrast, Alberta and Scotland showed delayed adoption with lower peak DES use, respectively, 56% and 58% of lesions by early 2006. Adoption of DES in Belgium was more gradual and peak use of 35% lower than other registries. Reductions in DES use were seen in all data sets during 2006, although this varied in absolute and relative terms and by clinical subgroup. CONCLUSION: Adoption and use of DES showed wide variation in four countries. The determinants of use are complex, and it is likely that nonclinical factors predominate. Recent reductions in use may be as a consequence of publicity and concerns regarding late stent thrombosis. The optimum application of DES in clinical practice is unclear and is reflected in the degree of international variation demonstrated. [less ▲]

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See detailRisque de restenose et d'evenements cardiaques apres angioplastie coronaire chez le patient diabetique: reduction par des approches pharmacologiques systemiques.
Nyssen, Anne-Sophie ULg; Legrand, Victor ULg; Scheen, André ULg

in Revue Médicale de Liège (2009), 64(4), 192-8

Various systemic pharmacological approaches have been evaluated to reduce the risk of restenosis after coronary angioplasty, with or without stent, in the general population and in diabetic patients who ... [more ▼]

Various systemic pharmacological approaches have been evaluated to reduce the risk of restenosis after coronary angioplasty, with or without stent, in the general population and in diabetic patients who are at increased risk for such complication. The aim of the present paper is to describe the effects of the main pharmacological classes on the risk of restenosis, the need for new revascularisation procedures and the incidence of major clinical events (MACE: death, myocardial infarction, revascularisation). We will analyse the role of antiplatelet agents, omega-3 fatty acids, statins, anti-inflammatory compounds, immunomodulators, anti-oxidants, glitazones and, finally, classical antidiabetic drugs such as metformin and insulin. Whenever possible, we will focus our attention on the results obtained in the diabetic population. [less ▲]

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See detailA large-scale multicentre study of patient skin doses in interventional cardiology: dose-area product action levels and dose reference levels.
Bogaert, E.; Bacher, K.; Lemmens, K. et al

in The British journal of radiology (2009), 82(976), 303-12

For 318 patients in 8 different Belgian hospitals, the entire skin-dose distribution was mapped using a grid of 70 thermoluminescence dosimeters per patient, allowing an accurate determination of the ... [more ▼]

For 318 patients in 8 different Belgian hospitals, the entire skin-dose distribution was mapped using a grid of 70 thermoluminescence dosimeters per patient, allowing an accurate determination of the maximum skin dose (MSD). Dose-area product (DAP) values, exposure parameters and geometry, together with procedure, patient and cardiologist characteristics, were also registered. Procedures were divided into two groups: diagnostic procedures (coronary angiography) and therapeutic procedures (dilatation, stent, combined procedures (e.g. coronary angiography + dilatation + stent)). The mean value of the MSD was 0.310 Gy for diagnostic and 0.699 Gy for therapeutic procedures. The most critical projection for receiving the MSD is the LAO90 (left anterior oblique) geometry. In 3% of cases, the MSD exceeded the 2 Gy dose threshold for deterministic effects. Action levels in terms of DAP values as the basis for a strategy for follow-up of patients for deterministic radiation skin effects were derived from measured MSD and cumulative DAP values. Two DAP action levels are proposed. A first DAP action level of 125 Gy cm(2) corresponding to the dose threshold of 2 Gy would imply an optional radiopathological follow-up depending on the cardiologist's decision. A second DAP action level of 250 Gy cm(2) corresponding to the 3 Gy skin dose would imply a systematic follow-up. Dose reference levels - 71.3 Gy cm(2) for diagnostic and 106.0 Gy cm(2) for therapeutic procedures - were derived from the 75 percentile of the DAP distributions. As a conclusion, we propose that total DAP is registered in patient's record file, as it can serve to improve the follow-up of patients for radiation-induced skin injuries. [less ▲]

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See detailAnticorps monoclonaux en cardiologie.
Legrand, Victor ULg

in Revue medicale de Liege (2009), 64(5-6), 310-2

Clinical efficacy of antiplatelet agents administration to reduce ischemic complications has supported the concept of atherothrombosis and plaque rupture. Specifically, administration of monoclonal ... [more ▼]

Clinical efficacy of antiplatelet agents administration to reduce ischemic complications has supported the concept of atherothrombosis and plaque rupture. Specifically, administration of monoclonal antibody against platelet membrane receptor glycoprotein IIb/IIa was shown to be highly effective whenever percutaneous intervention is performed in the setting of unstable coronary syndrome. The in-hospital use of glycoprotein IIb/IIIa is unanimously recommended in these situations. [less ▲]

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See detailElevation des biomarqueurs cardiaques apres un effort physique intense.
DUGAUQUIER, Christophe ULg; Hanssen, M.; GACH, Olivier ULg et al

in Revue medicale de Liege (2009), 64(7-8), 370-2

We present the case of a patient who felt faint after a strenuous exercise. A coronary angiography was performed because of an elevated level of troponin, but it failed to demonstrat any significant ... [more ▼]

We present the case of a patient who felt faint after a strenuous exercise. A coronary angiography was performed because of an elevated level of troponin, but it failed to demonstrat any significant coronary stenosis. We discuss the effect of strenuous exercise on cardiac biomarkers. Most previous published studies involved young trained populations. The frequency of these abnormalities in older, less trained people is unknown. Moreover, the possible impact of these abnormalities on mid- or long-term outcome is a matter of debate. Seniors practising intensive sport activities should systematically be submitted to a cardiological evaluation. [less ▲]

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See detailMeeting report ESC forum on drug eluting stents, European Heart House, Nice, 27-28 September 2007.
Daemen, Joost; Simoons, Maarten L.; Wijns, William et al

in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology (2009), 4(4), 427-36

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See detailCurrent-induced giant vortex and asymmetric vortex confinement in microstructured superconductors
Chao, X. H.; Zhu, B. Y.; Silhanek, Alejandro ULg et al

in Physical Review. B : Condensed Matter (2009), 80(5),

Based on the time-dependent Ginzburg-Landau equations, we study numerically current-driven vortices in a micrometer size square type-II superconductor. We demonstrate that the applied current ... [more ▼]

Based on the time-dependent Ginzburg-Landau equations, we study numerically current-driven vortices in a micrometer size square type-II superconductor. We demonstrate that the applied current significantly influences the dynamics of the vortices entering the sample. Strikingly, we find that a giant vortex can be created by the current-assisted collision of two singly quantized vortices. [less ▲]

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See detailDecline Of Endemic Oncocyclus Irises (Iridaceae) Of Lebanon: Survey And Conservation Needs
Saad, Layla ULg; Talhouk, Salma; Mahy, Grégory ULg

in Oryx (2009), 43(1), 91-96

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See detailBelgian consensus guidelines for follow-up of women with cervical cytological abnormalities.
Cuvelier, C. A.; Bogers, J. P.; Bourgain, C. et al

in Acta Clinica Belgica (2009), 64(2), 136-43

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See detailEfficacite anti-fracturaire de l'ibandronate administre par voie intraveineuse: de la complexite des etudes epidemiologiques interventionnelles a la pratique quotidienne.
Neuprez, A.; Hiligsmann, Mickaël ULg; Bruyère, Olivier ULg et al

in Revue Médicale de Liège (2009), 64(10), 525-9

Numerous epidemiological approaches are used to demonstrate the efficacy of a new chemical entity. In postmenopausal osteoporosis, anti-fracture efficacy can be assessed through prospective, randomized ... [more ▼]

Numerous epidemiological approaches are used to demonstrate the efficacy of a new chemical entity. In postmenopausal osteoporosis, anti-fracture efficacy can be assessed through prospective, randomized controlled trials, meta-analyses or real-life setting studies. Intravenous ibandronate was recently marketed, with the aim of optimizing drug absorption and adherence to treatment. Furthermore, this new formulation avoids gastrointestinal side effects and constrains linked to the oral intake of the medication. Spinal anti-fracture efficacy of IV ibandronate derives from a non-inferiority bridging study, using surrogate endpoints, i.e., bone mineral density and biochemical markers of bone turnover, compared to the oral daily formulation, previously registered for the treatment of osteoporosis in Europe. Coherent results from two separate meta-analyses have suggested that the non-vertebral anti-fracture efficacy of IV ibandronate is similar to that observed with oral, daily and weekly bisphosphonates. Similarly, a recent real-life setting study, based on claims from an US database, suggests that hip fractures are reduced, with IV ibandronate, to the same extend as they are with oral bisphosphonates. Notwithstanding, those results should probably be confirmed in an European setting, before being extrapolated, in daily practice, to the Belgian population. [less ▲]

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See detailLa Semois et son bassin, histoire d'un contrat de rivière
Rosillon, Françis ULg; Lobet, Jérôme ULg; Tassin, Mélanie ULg et al

in Au fil de la Semois (2009)

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See detailLes traitements biologiques en rhumatologie
Von Frenckell, Christian ULg; Malaise, Michel ULg

in Revue Médicale de Liège (2009), 64(5-6), 293-300

Biological therapies consisting of monoclonal antibodies and soluble receptors have revolutionized the care of rheumatologic patients. These therapies ensued from a better understanding of the ... [more ▼]

Biological therapies consisting of monoclonal antibodies and soluble receptors have revolutionized the care of rheumatologic patients. These therapies ensued from a better understanding of the physiopathology of rheumatologic disorders. Most of the latter have been concerned: rheumatoid arthritis (for about 10 years), psoriatic arthritis and ankylosing spondilitys (for more or less five years). Rheumatology was among the first disciplines to make use of these advances; it continues to benefit from the results of intense research efforts. These developments request from clinicians an increased expertise in immunology. [less ▲]

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See detailLes matières colorantes au début du Paléolithique supérieur : sources, transformations et fonctions
Salomon, Hélène ULg

Doctoral thesis (2009)

Abstract : Despite an increasing number of studies, colouring materials are still poorly understood among excavation remains. Their attraction lies in their capacity to bring to light diverse and complex ... [more ▼]

Abstract : Despite an increasing number of studies, colouring materials are still poorly understood among excavation remains. Their attraction lies in their capacity to bring to light diverse and complex skills, but also in their intense colouring power and their contrasting colours : red and black, which still possess a symbolic value. These highly symbolic materials may, therefore, highlight the “conceptual” practices of prehistoric men and give access to their symbolic world and thought. In such a particular context as the transition between the Middle and the Upper Palaeolithic, these remains, which are very abundant in most excavations, offer the possibility, through analysis, to get an exceptional insight into the way of life of the last Neanderthals. The Châtelperronian site of the “Grotte du Renne”, in Arcy-sur-Cure (Yonne), is a landmark. It was excavated beween 1949 and 1963 by André Leroi-Gourhan : Numerous colouring materials were discovered there, and Leroi-Gourhan developed theories about their transformation and uses which so far have not been tested, and have remained unchallenged.Since their discovery, the assumption is that those minerals were heated in a controlled way, in order to modify their colour. It is indeed well-known that heat transforms yellow materials (iron hydroxides) in orange, red or purple materials (iron oxides). From this hypothesis originates the theory according to which Neanderthals exploited colouring materials as pigments for symbolic or even aesthetic purposes. But the theory has so far never been proved true. Our study combines several sets of data, obtained from different methods. Physico-chemical and petrological analyses were carried out on the colouring materials. These data were related to their location on the site, in association with exceptionally well preserved “hut” structures. Furthermore, a series of experimentations, aimed to characterize powders obtained via different methods (grinding and crushing on the one hand, abrasion on the other hand). The comparison of all these data enabled us to identify the various technical choices which informed the supply in colouring minerals in all the Châtelperronian levels of the Grotte du Renne. It was thus possible to demonstrate that none of these materials, either red or black, was heated before being used, contrary to what had been assumed so far. The supply in colouring materials was as carefully organised as for other materials (flint, for example) ; they were collected in geological formations occasionally showing on the surface, at more than 10 km from the cave. The exploitation of these geological sites did not vary during the whole Châtelperronian period, and privileged materials which can easily be ground into powder. Part of their supply was ground coarsely in order to cover large surface areas (soils or hides) as preservative or to clean them up. The remaining materials were destined to more meticulous activities, which required a fine, regular, and highly-colouring powder. In this latter case, the Neanderthals of the Grotte du Renne used those products when working on bone materials (bone or mammoth ivory), and used them also for their sheer colour. The set of colouring minerals from the Grotte du Renne reveals Neanderthals’ in-depth knowledge of materials ; they understood perfectly well their properties and qualities, and used them extensively, so that the Châtelperronian site must have been a literally dazzling sight, all red and black. The “chaîne opératoire” which transpires from our analysis shows very sophisticated techniques, and an advanced “technological” knowledge. They are witness to surprising capacities and a highly-evolved pattern of thought. [less ▲]

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See detailTrophic niches of thirteen damselfishes (Pomacentridae) at the Grand Récif of Toliara, Madagascar
Frederich, Bruno ULg; Fabri, Grégory ULg; Lepoint, Gilles ULg et al

in Ichthyological Research (2009), 56

The damselfishes, with more than 340 species, constitute one of the most important families that live in the coral reef environment. Most of our knowledge of reef-fish ecology is based on this family, but ... [more ▼]

The damselfishes, with more than 340 species, constitute one of the most important families that live in the coral reef environment. Most of our knowledge of reef-fish ecology is based on this family, but their trophic ecology is poorly understood. The aim of the present study was to determine the trophic niches of 13 sympatric species of damselfishes by combining stable isotope (d15N and d13C) and stomach content analyses. Isotopic signatures reveal three main groups according to their foraging strategies: pelagic feeders (Abudefduf sexfasciatus, A. sparoides, A. vaigiensis, Chromis ternatensis, C. dimidiata, Dascyllus trimaculatus and Pomacentrus caeruleus), benthic feeders (Chrysiptera unimaculata, Plectroglyphidodon lacrymatus and Amphiprion akallopisos) and an intermediate group (D. aruanus, P. baenschi and P. trilineatus). Stomach contents reveal that planktonic copepods and filamentous algae mainly represent the diets of pelagic feeders and benthic feeders, respectively. The intermediate position of the third group resulted from a partitioning of small planktonic prey, small vagile invertebrates and filamentous algae. In this last feeding group, the presence of a wide range of d13C values in P. trilineatus suggests a larger trophic niche width, related to diet-switching over time. Some general considerations about the feeding habits of damselfishes reveal that their choice of habitat on the reef and their behavior appear to be good predictors of diet in this group. Benthic (algae and/or small invertebrates) feeders appear to be solitary and defend a small territory on the bottom; zooplankton feeders remain in groups just above the reef, in the water column. [less ▲]

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See detailPotential mechanism of sound production in Oreochromis niloticus (Cichlidae)
Longrie, Nicolas ULg; Van Wassenbergh, Sam; Mauguit, Quentin ULg et al

in Journal of Experimental Biology (2009), 212

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