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See detailReactivity towards singlet oxygen of propofol inside liposomes and neuronal cells
Heyne, Belinda; Brault, Daniel; Fontaine-Aupart, Marie-Pierre et al

in Biochimica et Biophysica Acta - General Subjects (2005), 1724

Singlet oxygen (1O2), a reactive oxygen species, has been found to be implicated in many cellular events and pathological disorders.Herein, we investigated the reactivity of 1O2 towards the anaesthetic ... [more ▼]

Singlet oxygen (1O2), a reactive oxygen species, has been found to be implicated in many cellular events and pathological disorders.Herein, we investigated the reactivity of 1O2 towards the anaesthetic agent propofol (PPF) encapsulated within DMPC liposomes. By time resolved luminescence, the rate constant of 1O2 quenching by PPF was evaluated, depending on the location of the sensitizer. The nature of the oxidation product, resulting from the reaction of 1O2 with PPF, was determined using absorption and HPLC techniques. Finally, the in vitro protective effect of PPF towards the1O2-induced neuronal cell toxicity was evaluated in terms of cell viability. [less ▲]

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See detailQuelle place pour le cinéma à l'école?
Van Cauwenberge, Geneviève ULg

in Puzzle (2005), 18

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See detailMulti-frequency passive non-linear targeted energy transfers in systems of couples oscillators
Tsakirtzis, Stylianos; Panagopoulos, Panagiotis; Kerschen, Gaëtan ULg et al

in 5th GRACM International Congress on Computational Mechanics, Limassol, 2005 (2005, June)

We study the dynamics of a system of coupled linear oscillators with a multi-DOF end attachment with essential (nonlinearizable) stiffness nonlinearities. We show numerically that the multi-DOF attachment ... [more ▼]

We study the dynamics of a system of coupled linear oscillators with a multi-DOF end attachment with essential (nonlinearizable) stiffness nonlinearities. We show numerically that the multi-DOF attachment with damping can passively absorb broadband energy from the linear system in a one-way, irreversible fashion, acting in essence as nonlinear energy sink (NES). Strong passive targeted energy transfer from the linear to the nonlinear subsystem is possible, over wide frequency and energy ranges. We numerically demonstrate that the topological structure of the periodic orbits in the frequency – energy plane of the underlying hamiltonian system greatly influences the strength of targeted energy transfer in the damped system, and governs to a great extent the overall transient damped dynamics. This work may be regarded as a contribution towards proving the efficacy the utilizing essentially nonlinear attachments as passive broadband boundary controllers. [less ▲]

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See detailTwo-year efficacy and tolerability of once-monthly oral ibandronate in postmenopausal osteoporosis: the MOBILE study
Cooper, C.; Delmas, P. D.; Felsenberg, D. et al

in Annals of the Rheumatic Diseases (2005, June), 64(Suppl.III), 68

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See detailOnce-monthly and daily oral ibandronate are at least as effective in improving proximal femur BMD in postmenopausal osteoporosis: 12-month data from MOBILE
Reginster, Jean-Yves ULg; Lorenc, R.; Stepan, J. J. et al

in Annals of the Rheumatic Diseases (2005, June), 64(Suppl.III), 93

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See detailReduction in the risk of back pain persists at least 30 months after discontinuation of teriparatide treatment: a meta-analysis
Reginster, Jean-Yves ULg; Nevitt, M. C.; Chen, P. et al

in Annals of the Rheumatic Diseases (2005, June), 64(Suppl.III), 521

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See detailStrontium ranelate reduces the risk of vertebral fractures in osteoporotic postmenopausal women whatever the baseline vertebral fractures status
Roux, Christian; Fardellone, P.; Fechtenbaum, Jacques et al

in Annals of the Rheumatic Diseases (2005, June), 64(Suppl.III), 359

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See detailGlobal prevalence and skeletal implications of vitamin D inadequacy
Reginster, Jean-Yves ULg; Richy, Florent; Rabenda, Véronique ULg et al

in Annals of the Rheumatic Diseases (2005, June), 64(Suppl.III), 362

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See detailIntravenous ibandronate injections are at least as effective as daily oral ibandronate: consistent effect across subgroups
Reginster, Jean-Yves ULg; Stepan, J. J.; Halse, J. et al

in Annals of the Rheumatic Diseases (2005, June), 64(Suppl.III), 365

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See detailUpper gastrointestinal safety and tolerability profile of once-monthly and daily oral ibandronate is similar in postmenopausal osteoporosis: 1-year results from MOBILE
Adami, Silvio; Tanko, L. B.; Nuti, R. et al

in Annals of the Rheumatic Diseases (2005, June), 64(Suppl.III), 364

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See detailPreoperative hyperfractionated accelerated radiotherapy (HART) in locally advanced rectal cancer (LARC) immediately followed by surgery. A prospective phase II trial
Coucke, Philippe ULg; Notter; Stamm et al

in Radiotherapy & Oncology (2005)

Background and purpose We aim to report on local control in a phase II trial on preoperative hyperfractionated and accelerated radiotherapy schedule (HART) in locally advanced resectable rectal cancer ... [more ▼]

Background and purpose We aim to report on local control in a phase II trial on preoperative hyperfractionated and accelerated radiotherapy schedule (HART) in locally advanced resectable rectal cancer (LARC). This fractionation schedule was designed to keep the overall treatment time (OTT) as short as possible. Patients and methods This is a prospective trial on patients with UICC stages II and III rectal cancer. The patients were submitted to a total dose of 41.6 Gy, delivered in 2.5 weeks at 1.6 Gy per fraction twice a day with a 6-h interfraction interval. Surgery was performed within 1 week after the end of irradiation. Adjuvant chemotherapy was delivered in a subset of patients. Results Two hundred and seventy nine patients were entered and 250 are fully assessable, with a median follow-up of 39 months. The 5-years actuarial local control (LC) rate is 91.7%. The overall survival (OS) is 59.6%. The freedom from disease relapse (FDR) is 71.5%. Downstaging was observed in 38% of the tumors. Conclusion The actuarial LC at 5 years is 91.7%, although we are dealing with stages II–III LARC, mainly located in the lower rectum (median distance=5 cm). The pattern of failure is dominated by distant metastases and treatment intensification will obviously require a systemic approach. [less ▲]

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See detailBelgian consensus on metabolic problems associated with atypical antipsychotics
De Nayer, A.; De Hert, M.; Scheen, André ULg et al

in International Journal of Psychiatry in Clinical Practice (2005), 9(2), 130-137

A workshop was convened by a panel of psychiatrists, diabetologists and pharmacists from major Belgian hospitals to review the latest information relating to the risks with second-generation ... [more ▼]

A workshop was convened by a panel of psychiatrists, diabetologists and pharmacists from major Belgian hospitals to review the latest information relating to the risks with second-generation antipsychotics (SGA) for the development of metabolic disorders, especially impaired glucose tolerance, diabetes mellitus and dyslipidemia. The panelists sought to formulate recommendations for practising psychiatrists when initiating and maintaining therapy with SGA, and for the switch of SGA or initiation of further treatment if metabolic complications occur. In addition, recommendations for counselling of the patient and for the cooperation between the psychiatrist and the general physician or diabetologist, respectively, were provided. [less ▲]

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See detailA reinforcement learning based discrete supplementary control for power system transient stability enhancement
Glavic, M.; Ernst, Damien ULg; Wehenkel, Louis ULg

in Engineering Intelligent Systems for Electrical Engineering and Communications (2005), 13(2 Sp. Iss. SI), 81-88

This paper proposes an application of a Reinforcement Learning (RL) method to the control of a dynamic brake aimed to enhance power system transient stability. The control law of the resistive brake is in ... [more ▼]

This paper proposes an application of a Reinforcement Learning (RL) method to the control of a dynamic brake aimed to enhance power system transient stability. The control law of the resistive brake is in the form of switching strategies. In particular, the paper focuses on the application of a model based RL method, known as prioritized sweeping, a method proven to be suitable in applications in which computation is considered to be cheap. The curse of dimensionality problem is resolved by the system state dimensionality reduction based on the One Machine Infinite Bus (OMIB) transformation. Results obtained by using a synthetic four-machine power system are given to illustrate the performances of the proposed methodology. [less ▲]

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See detailAccurate photometric light curves of the lensed components of Q2237+0305 derived with an optimal image subtraction technique: Evidence for microlensing in image A
Moreau, O.; Libbrecht, C.; Lee, D. W. et al

in Astronomy and Astrophysics (2005), 436(2), 479-492

Using an optimal image subtraction technique, we have derived the V and R light curves of the four lensed QSO components of Q2237+0305 from the monitoring CCD frames obtained by the GLITP collaboration ... [more ▼]

Using an optimal image subtraction technique, we have derived the V and R light curves of the four lensed QSO components of Q2237+0305 from the monitoring CCD frames obtained by the GLITP collaboration with the 2.6m NOT telescope in 1999/2000 (Alcalde et al. 2002). We give here a detailed account of the data reduction and analysis and of the error estimates. In agreement with Wozniak et al. (2000a,b), the good derived photometric accuracy of the GLITP data allows to discuss the possible interpretation of the light curve of component A as due to a microlensing event taking place in the deflecting galaxy. This interpretation is strengthened by the colour dependence of the early rise of the light curve of component A, as it probably corresponds to a caustics crossing by the QSO source. [less ▲]

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See detailNon-thermal radio emission from O-type stars. I. HD168112
Blomme, Ronny; Van Loo, S.; De Becker, Michaël ULg et al

in Astronomy and Astrophysics (2005), 436(3), 1033-1040

We present a radio lightcurve of the O5.5 III(f(+)) star HD 168112, based on archive data from the Very Large Array (VLA) and the Australia Telescope Compact Array (ATCA). The fluxes show considerable ... [more ▼]

We present a radio lightcurve of the O5.5 III(f(+)) star HD 168112, based on archive data from the Very Large Array (VLA) and the Australia Telescope Compact Array (ATCA). The fluxes show considerable variability and a negative spectral index, thereby confirming that HD 168112 is a non-thermal radio emitter. The non-thermal radio emission is believed to be due to synchrotron radiation from relativistic electrons that have been Fermi accelerated in shocks. For HD 168112, it is not known whether these shocks are due to a wind-wind collision in a binary system or to the intrinsic instability of the stellar wind driving mechanism. Assuming HD 168112 to be a single star, our synchrotron model shows that the velocity jump of the shocks should be very high, or there should be a very large number of shocks in the wind. Neither of these is compatible with time-dependent hydrodynamical calculations of O star winds. If, on the other hand, we assume that HD 168112 is a binary, the high velocity jump is easily explained by ascribing it to the wind-wind collision. By further assuming the star to be an eccentric binary, we can explain the observed radio variability by the colliding-wind region moving in and out of the region where free-free absorption is important. The radio data presented here show that the binary has a period of between one and two years. By combining the radio data with X-ray data, we find that the most likely period is similar to 1.4 yr. [less ▲]

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See detailLa parité linguistique au sein du conseil des ministres
Reuchamps, Min ULg

Master's dissertation (2005)

Since 1970, the Belgian Constitution requires that the federal Council of Ministers be staffed by an equal number of Dutch-speaking and French-speaking ministers, with the possible exception of the Prime ... [more ▼]

Since 1970, the Belgian Constitution requires that the federal Council of Ministers be staffed by an equal number of Dutch-speaking and French-speaking ministers, with the possible exception of the Prime Minister. This thesis explores the constitutional rule of linguistic parity at the highest level of the state. Using the existing “model of points” and the author’s own “model of the weight of ministerial portfolios”, the study analyses the last twenty-three federal Governments (1970-2007) and shows that both Flemish and Francophone communities benefit from the parity: the former because it usually receives an extra minister –the Prime Minister– as well as more Secretaries of State and ensures a similar protection for its minority in Brussels; the latter because it enjoys a symbolic as well as a political guarantee of equal representation. Above all, the Council of Ministers is not only numerically well-balanced but also –and chiefly– politically well-balanced. [less ▲]

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See detailOpen Linking et OpenURL
Mottet, Philippe ULg

in Cahiers de la Documentation = Bladen voor Documentatie (2005), 59(2), 35-47

Les notions d’Open Linking, d’OpenURL, de sensibilité au contexte ou de copie appropriée sont largement répandues désormais dans le monde de l’information scientifique, même si on ne sait pas toujours ... [more ▼]

Les notions d’Open Linking, d’OpenURL, de sensibilité au contexte ou de copie appropriée sont largement répandues désormais dans le monde de l’information scientifique, même si on ne sait pas toujours précisément ce qui se cache sous cette terminologie un peu mystérieuse. Un système d’Open Linking permet, sur Internet et dans un cadre documentaire, de relier entre elles toutes les informations relatives à un sujet particulier grâce à des adresses URL/URI qui portent le nom d’OpenURL. Ces liens OpenURL sont créés dynamiquement à la suite de re-cherches bibliographiques et permettent de rebondir vers d’autres ressources électroniques proposant des in-formations complémentaires liées à la référence de départ et dont l’accès est autorisé pour l’utilisateur. La norme ANSI/NISO Z39.88 définit la syntaxe des liens OpenURL ainsi que les métadonnées, identifiants et protocoles d’échange de communication qui peuvent y être incorporés. [less ▲]

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