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See detaileCole - Projet d'apprentissage et de remédiation en ligne
Jérôme, Françoise ULg; Vreeswijk, Valérie ULg; Georges, François ULg et al

Report (2008)

Recherche-développement consacrée à la conception d'un dispositif en ligne susceptible de soutenir l'autonomisation des apprenants dans le déploiement des compétences "lire" et "écrire" en français.

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See detailRefining Topological Relations between Regions Considering Their Shapes
Billen, Roland ULg; Kurata, Yohei

in Lecture Notes in Computer Science (2008), 5266/2008

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See detailIntroduire les dérivées par les vitesses. Pour qui ? Pourquoi ? Comment ?
Gantois; Schneider, Marguerite ULg

in Petit X (2008), 79

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See detailIntroduction à Octave
Charles, Catherine ULg

in Notes de Statistique et d'Informatique (2008)

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See detailImplicit/explicit memory dissociation in Alzheimer's disease: the consequence of inappropriate processing?
Willems, Sylvie ULg; Salmon, Eric ULg; Van der Linden, Martial ULg

in Neuropsychology (2008), 22(6), 710-7

Dual-process theories of recognition posit that perceptual fluency contributes to both familiarity-based explicit recognition and perceptual priming. However, the priming-without-recognition dissociation ... [more ▼]

Dual-process theories of recognition posit that perceptual fluency contributes to both familiarity-based explicit recognition and perceptual priming. However, the priming-without-recognition dissociation, as observed through the intact mere exposure effect and impaired recognition in patients with Alzheimer's disease (AD), might indicate that familiarity and perceptual priming are functionally distinct. This study investigated whether the AD patients' processing strategies at testing may explain this priming-without-recognition dissociation. First, we replicated the priming-without-recognition effect in 16 patients who exhibited intact exposure effects despite null recognition. Second, we showed that, under identical conditions, inducing a holistic processing strategy during recognition testing increased AD patients' recognition--performance was similar for AD patients and healthy control participants. Furthermore, prompting analytic processing during both priming and recognition tasks decreased AD patients' performance in both tasks. These findings suggest that the extent to which AD patients use perceptual fluency in priming and recognition tasks is contingent on their processing approach. The choice of processing strategy may depend on how difficult patients perceive the task to be. [less ▲]

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See detailChronic kidney disease in Taiwan.
Delanaye, Pierre ULg; Cavalier, Etienne ULg; Krzesinski, Jean-Marie ULg

in Lancet (2008), 372(9654), 19501950-1

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See detailSpinocerebellar ataxia type 2 (SCA2): clinical features and genetic analysis.
Mutesa, Leon; Pierquin, Geneviève ULg; Segers, Karin ULg et al

in Journal of Tropical Pediatrics (2008), 54(5), 350-2

Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominant neurodegenerative disease that results from the expansion of an unstable trinucleotide CAG repeat encoding for a polyglutamine tract. In ... [more ▼]

Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominant neurodegenerative disease that results from the expansion of an unstable trinucleotide CAG repeat encoding for a polyglutamine tract. In normal individuals, alleles contain between 14 and 31 CAG repeats, whereas the pathological alleles have more than 35 CAG repeats. The clinical phenotype of SCA2 includes a progressive cerebellar ataxia with additional features such as ophthalmoplegia, extra-pyramidal or pyramidal signs and peripheral neuropathy. We report a SCA2 large African family with several affected individuals. A major pathological allele carrying 43 CAG repeats was identified in the proband. To our knowledge, this is a first report of a SCA disorder described in Central African patients, thus indicating the need to consider this diagnosis in young African ataxic patients. [less ▲]

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See detailComment j'explore... un lymphome T cutane. Nouveaux horizons.
Quatresooz, Pascale ULg; Pierard, Claudine ULg; Pierard, Gérald ULg

in Revue Médicale de Liège (2008), 63(4), 208-12

Although cutaneous T cell lymphomas remain rare, their incidence seems progressively on the rise. The main diagnostic criteria are issued from the clinico-pathological confrontation. Other methods help ... [more ▼]

Although cutaneous T cell lymphomas remain rare, their incidence seems progressively on the rise. The main diagnostic criteria are issued from the clinico-pathological confrontation. Other methods help support the diagnosis and establish a prognosis. [less ▲]

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See detailLe cas clinique du mois. Pemphigoide bulleuse apres brulure thermique.
Blaise, G.; Pierard, Claudine ULg; Quatresooz, Pascale ULg et al

in Revue Médicale de Liège (2008), 63(4), 182-3

In rare instances, some injuring physical factors such as thermal burns can be at the origin of bullous pemphigoid lesions. The early lesions are most often restricted to the injured skin area. Secondary ... [more ▼]

In rare instances, some injuring physical factors such as thermal burns can be at the origin of bullous pemphigoid lesions. The early lesions are most often restricted to the injured skin area. Secondary generalization is the natural evolution to be expected. However, once the episode is resolved, recurrence is exceptional. When the natural history of bullous pemphigoid differs from the regular type, the peculiar condition of development of these lesions does not change any of the diagnostic clinical and histological criteria, as well as the therapeutic procedures to follow. [less ▲]

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See detailMutational analysis of the zinc- and substrate-binding sites in the CphA metallo-beta-lactamase from Aeromonas hydrophila.
Bebrone, Carine ULg; Anne, Christine; Kerff, Frédéric ULg et al

in Biochemical Journal (2008), 414(1), 151-9

The subclass B2 CphA (Carbapenemase hydrolysing Aeromonas) beta-lactamase from Aeromonas hydrophila is a Zn(2+)-containing enzyme that specifically hydrolyses carbapenems. In an effort to evaluate ... [more ▼]

The subclass B2 CphA (Carbapenemase hydrolysing Aeromonas) beta-lactamase from Aeromonas hydrophila is a Zn(2+)-containing enzyme that specifically hydrolyses carbapenems. In an effort to evaluate residues potentially involved in metal binding and/or catalysis (His(118), Asp(120), His(196) and His(263)) and in substrate specificity (Val(67), Thr(157), Lys(224) and Lys(226)), site-directed mutants of CphA were generated and characterized. Our results confirm that the first zinc ion is in interaction with Asp(120) and His(263), and thus is located in the 'cysteine' zinc-binding site. His(118) and His(196) residues seem to be interacting with the second zinc ion, as their replacement by alanine residues has a negative effect on the affinity for this second metal ion. Val(67) plays a significant role in the binding of biapenem and benzylpenicillin. The properties of a mutant with a five residue (LFKHV) insertion just after Val(67) also reveals the importance of this region for substrate binding. This latter mutant has a higher affinity for the second zinc ion than wild-type CphA. The T157A mutant exhibits a significantly modified activity spectrum. Analysis of the K224Q and N116H/N220G/K224Q mutants suggests a significant role for Lys(224) in the binding of substrate. Lys(226) is not essential for the binding and hydrolysis of substrates. Thus the present paper helps to elucidate the position of the second zinc ion, which was controversial, and to identify residues important for substrate binding. [less ▲]

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See detailLe medicament du mois. Exenatide (Byetta). Incretinomimetique indique dans le traitement du diabete de type 2 apres echec et en complement des antidiabetiques oraux.
Scheen, André ULg; Van Gaal, L. F.

in Revue Médicale de Liège (2008), 63(3), 158-65

Exenatide (Byetta) is a synthetic derivative of exendin-4 and an agonist of receptors of glucagon-like peptide-1 (GLP-1). It is resistant to the rapid inactivation by dipeptidylpeptidase-4 and acts as an ... [more ▼]

Exenatide (Byetta) is a synthetic derivative of exendin-4 and an agonist of receptors of glucagon-like peptide-1 (GLP-1). It is resistant to the rapid inactivation by dipeptidylpeptidase-4 and acts as an incretin mimetic. It stimulates insulin secretion by the B cell in a glucose-dependent manner whereas it inhibits glucagon secretion. Exenatide improves mainly postprandial glucose concentrations and lowers glycated haemoglobin (HbA(1c)) levels, without being directly responsible for hypoglycaemia or requiring mandatory home blood glucose monitoring. Furthermore, it slows down gastric emptying and promotes sustained body weight reduction, even in absence of frequently reported nausea following treatment initiation. Exenatide is recommended and reimbursed in Belgium for the treatment of type 2 diabetes, in combination with metformin and a sulfonylurea, in patients not adequately controlled with maximal tolerated doses of these oral glucose-lowering agents. Exenatide is presented as pre-filled pens for subcutaneous injection. The recommended initial dose is 5 microg before morning and evening meals, to be up titrated to 10 microg twice daily. Exenatide may represent a valuable alternative to insulin therapy, especially in overweight or obese patients with type 2 diabetes and not ready to perform home blood glucose monitoring. [less ▲]

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See detailThorough analysis of input physics in CESAM and CLÉS codes
Montalban Iglesias, Josefa ULg; Lebreton, Yveline; Miglio, Andrea ULg et al

in Astrophysics & Space Science (2008), 316(1-4), 219-229

This contribution is not about the quality of the agreement between stellar models computed by CESAM and CLÉS codes, but more interesting, on what ESTA-Task 1 run has taught us about these codes and about ... [more ▼]

This contribution is not about the quality of the agreement between stellar models computed by CESAM and CLÉS codes, but more interesting, on what ESTA-Task 1 run has taught us about these codes and about the input physics they use. We also quantify the effects of different implementations of the same physics on the seismic properties of the stellar models, that in fact is the main aim of ESTA experiments. [less ▲]

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See detailFallopian tube insertion into the uterine cavity discovered accidentally during laparoscopic retrieval of a misplaced coil from the pelvic cavity
Panayotidis, Costas; Foidart, Jean-Michel ULg; Nisolle, Michelle ULg

in Gynecological Surgery (2008), 5(2), 125-7

This article presents for the first time in the literature a case of fallopian tube insertion into the uterine cavity discovered accidentally during laparoscopic retrieval of a misplaced coil from the ... [more ▼]

This article presents for the first time in the literature a case of fallopian tube insertion into the uterine cavity discovered accidentally during laparoscopic retrieval of a misplaced coil from the pelvic cavity. [less ▲]

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See detailA new design model for the resistance of steel semi-compact cross-sections
Boissonnade, N.; Jaspart, Jean-Pierre ULg; Oerder, R. et al

in Proceedings of EUROSTEEL 2008 (2008)

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See detailRapport 1 (comité de thèse)
Zirbes, Lara ULg

Report (2008)

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See detailBifidobacteria as indicators of faecal contamination along a sheep meat production chain
Delcenserie, Véronique ULg; Loncaric, D.; Bonaparte, Christine et al

in Journal of Applied Microbiology (2008), 104(1), 276-284

Aims: The potential use of bifidobacteria as indicators for faecal contamination was studied along a sheep meat production and processing chain. The levels of bifidobacteria were compared with those of ... [more ▼]

Aims: The potential use of bifidobacteria as indicators for faecal contamination was studied along a sheep meat production and processing chain. The levels of bifidobacteria were compared with those of Escherichia coli. Total viable counts were followed along the chain (244 samples). Methods and Results: Forty-three per cent of the samples contained bifidobacteria, of which 15% were solely detected using a PCR method based on the hsp60 gene and not by a culture-based method. Bifidobacteria were detected in only three of nine sheep faeces samples using one or the other method. However, carcasses (types C and E) were highly contaminated. These sample types (30% and 28%, respectively) were positive for bifidobacteria and negative for E. coli. The species Bifidobacterium pseudolongum and Bif. thermophilum, isolated from faecal samples, were predominant. Bifidobacterium choerinum were found in C, D, E and F sample types. Conclusions: Bifidobacteria were shown more efficient than E. coli in carcasses samples. The presence of Bif. choerinum suggested a faecal pork contamination. Significance and Impact of the Study: Detection and identification of bifidobacteria, in correlation with E. coli counting, should improve hygiene quality of mutton processing chains. [less ▲]

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See detailWest Gondwanan and Euramerican climate impact on Famennian miospore assemblages
Streel, Maurice ULg

in Subcommission on Devonian Stratigraphy Newsletter (2008), 23

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See detailRapid and easy development of versatile tools to study protein/ligand interactions
Vandevenne, Marylène ULg; Gaspard, Gilles ULg; Yilmaz, Nursel et al

in Protein engineering, design & selection (2008)

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