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See detailcompte rendu de : Black doves speak'. Herodotus and the languages of Barbarians
Rochette, Bruno ULg

in Historiographia Linguistica (2006), 33(1-2), 195-200

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See detailPhysicochemical And Biochemical Characterization Of Non-Biodegradable Cellulose In Miocene Gymnosperm Wood From The Entre-Sambre-Et-Meuse, Southern Belgium
Lechien, Valérie; Rodriguez, Christian; Ongena, MARC ULg et al

in Organic Geochemistry (2006), 37(11), 1465-1476

Specimens of Miocene fossil wood from the Entre-Sambre-et-Meuse karsts (southern Belgium) were examined using physicochemical and biochemical techniques in order to understand the reasons for the ... [more ▼]

Specimens of Miocene fossil wood from the Entre-Sambre-et-Meuse karsts (southern Belgium) were examined using physicochemical and biochemical techniques in order to understand the reasons for the exceptional preservation of these fossilized remains after 15 million years. Structural and chemical changes were assessed by comparing the structural features of the fossil samples with those of their modern counterpart, Metaseguoia. Solid state C-13 nuclear magnetic resonance (NMR) and microscopic analysis showed good preservation of the cellulose structure in the fossil wood from the Florennes peat deposit. Despite the substantial cellulose fraction available in the fossil tissue, an enzymatic degradation test and a biochemical methane potential assay showed that the fossil cellulose could not be degraded by cellulases and anaerobic microorganisms usually involved in the biodegradation of organic matter. Moreover, the cellulose structure (crystallinity and surface area) seemed to have no effect on cellulose biodegradability in these Miocene fossil wood samples. On the basis of our observations, we suggest that the presence of a modified lignin structure could greatly influence cellulose preservation/biodegradability. [less ▲]

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See detailTopiramate induces type 3 renal tubular acidosis by inhibiting renal carbonic anhydrase.
Sacre, Anne; JOURET, François ULg; Manicourt, Daniel et al

in Nephrology Dialysis Transplantation (2006), 21(10), 2995-6

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See detailIdentification of the Core Structure of Lysozyme Amyloid Fibrils by Proteolysis
Frare, Erica; Mossuto, Maria F.; Polverino de Laureto, Patrizia et al

in Journal of Molecular Biology (2006), 361

Human lysozyme variants form amyloid fibrils in individuals suffering from a familial non-neuropathic systemic amyloidosis. In vitro, wild-type human and hen lysozyme, and the amyloidogenic mutants can be ... [more ▼]

Human lysozyme variants form amyloid fibrils in individuals suffering from a familial non-neuropathic systemic amyloidosis. In vitro, wild-type human and hen lysozyme, and the amyloidogenic mutants can be induced to form amyloid fibrils when incubated under appropriate conditions. In this study, fibrils of wild-type human lysozyme formed at low pH have been analyzed by a combination of limited proteolysis and Fouriertransform infrared (FTIR) spectroscopy, in order to map conformational features of the 130 residue chain of lysozyme when embedded in the amyloid aggregates. After digestion with pepsin at low pH, the lysozyme fibrils were found to be composed primarily of N and C-terminally truncated protein species encompassing residues 26–123 and 32–108, although a significant minority of molecules was found to be completely resistant to proteolysis under these conditions. FTIR spectra provide evidence that lysozyme fibrils contain extensive β-sheet structure and a substantial element of non β-sheet or random structure that is reduced significantly in the fibrils after digestion. The sequence 32–108 includes the β-sheet and helix C of the native protein, previously found to be prone to unfold locally in human lysozyme and its pathogenic variants. Moreover, this core structure of the lysozyme fibrils encompasses the highly aggregation-prone region of the sequence recently identified in hen lysozyme. The present proteolytic data indicate that the region of the lysozyme molecule that unfolds and aggregates most readily corresponds to the most highly protease-resistant and thus highly structured region of the majority of mature amyloid fibrils. Overall, the data show that amyloid formation does not require the participation of the entire lysozyme chain. The majority of amyloid fibrils formed from lysozyme under the conditions used here contain a core structure involving some 50% of the polypeptide chain that is flanked by proteolytically accessible N and C-terminal regions. [less ▲]

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See detailMethods to study protein aggregation and amyloid formation
Dumoulin, Mireille ULg; Bader, R.

in Protein & Peptide Letters (2006), 13

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See detailStranding of a humpback whale (Megaptera novaeangliae) on the Belgian coast
Jauniaux, Thierry ULg; Brenez, C.; Haelters, J. et al

in proceeding of the annual conference (2006)

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See detailEvolution des échouages et des causes de mortalité des mammifères marins dans le nord de la France (1995-2005)
Jauniaux, Thierry ULg; Brenez, C.; Haelters, J. et al

in annual proceeding (2006)

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See detailPrevention cardiovasculaire par l'aspirine chez le patient diabetique: que nous apprend la medecine factuelle?
Legrand, Delphine ULg; Scheen, André ULg

in Revue Médicale Suisse (2006), 2(76), 1904-8

Diabetes mellitus markedly increases the risk of cardiovascular diseases, with an especially elevated relative risk among women. Aspirin prescription is mandatory in secondary prevention, even if the ... [more ▼]

Diabetes mellitus markedly increases the risk of cardiovascular diseases, with an especially elevated relative risk among women. Aspirin prescription is mandatory in secondary prevention, even if the protection by aspirin appears less efficacious in diabetic than in non-diabetic patients. In primary prevention, available data are paradoxically rather scarce, but also suggest a less effective prevention when diabetes is present. Aspirin remains the first antiplatelet agent in the diabetic population in all international guidelines of cardiovascular prevention although a higher daily dose may be proposed in this subgroup of patients (160-300 mg rather than 75-100 mg). [less ▲]

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See detailDiabete sucre et decompensation cardiaque: specificites ethiopathogeniques et therapeutiques.
De Flines, Jenny ULg; Scheen, André ULg

in Revue Médicale Suisse (2006), 2(76), 1893-61898-900

Diabetes mellitus increases by 2.5 to 5 the relative risk of congestive heart failure. Besides the classical risk factors of congestive heart failure such as obesity, arterial hypertension and coronary ... [more ▼]

Diabetes mellitus increases by 2.5 to 5 the relative risk of congestive heart failure. Besides the classical risk factors of congestive heart failure such as obesity, arterial hypertension and coronary artery disease that are frequently associated to type 2 diabetes, a diabetic cardiomyopathy plays also a role. This specific complication is related to metabolic factors and oxidative stress, leading to muscular cell apoptosis and fibrosis. The management of a diabetic patient with congestive heart failure has several specificities not only concerning the treatment of cardiac insufficiency but most importantly concerning antidiabetic therapy. The relationship between glitazones, peripheral oedema and risk of congestive heart failure is currently raising much interest and controversies. [less ▲]

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See detailControverses a propos des criteres de jugement dans les essais cliniques de prevention cardiovasculaire.
Scheen, André ULg

in Revue Médicale Suisse (2006), 2(76), 1875-6

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See detailDoes the metabolic syndrome help to select patients requiring high statin dose?
Scheen, André ULg

in Lancet (2006), 368(9539), 893-4

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See detailUsefulness of glycosylated haemoglobin (HbA1c) to screen for diabetes in patients with schizophrenia.
Hanssens, Linda; De Hert, Marc; Van Eyck, Dominique et al

in Schizophrenia Research (2006), 85(1-3), 296-7

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See detailÉtude morphologique et immunocytologique du développement prénatal de l’organe de Corti chez le rat.
Thelen, Nicolas ULg

Master of advanced studies dissertation (2006)

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See detailInformation géographique tridimensionnelle
Saux, Eric; Billen, Roland ULg

in Revue internationale de Géomatique (2006), 16(1), 134

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See detailPaying Attention to Language, Replicas and the Role of the Artist in Janet Frame's Living in the Maniototo
Tunca, Daria ULg

in Journal of Postcolonial Writing (2006), 42(1), 32-43

Janet Frame's 1979 novel Living in the Maniototo features a ubiquitous narrator whose multiple personalities are linked by a common interest in creation. This choice of narrative perspective, coupled with ... [more ▼]

Janet Frame's 1979 novel Living in the Maniototo features a ubiquitous narrator whose multiple personalities are linked by a common interest in creation. This choice of narrative perspective, coupled with the characters and events depicted in the book, provides the basis for an exploration of the related concepts of art, language and replicas. By establishing connections between these elements, this article attempts to unveil the dynamics at work in the novel's multi-layered structure and thus shed light on the role of the artist in the narrative and, by extension, on the author's metafictional strategy. [less ▲]

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See detailGrotesque et ironie dans le théâtre de Jean-Marie Piemme
Delhalle, Nancy ULg

in Textyles : Revue des Lettres Belges de Langue Française (2006), 29

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See detailStrategies nouvelles et recompositions sociales autour de la faune dans le Bassin du Congo.
Vermeulen, Cédric ULg; Doucet, Jean-Louis ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2006), 10(3), 251-257

The faunaʼs overexploitation in the Congo basin in general and within logging concessions in particular case still appears as a crucial problematic. Commercial poaching threats not only mammal ... [more ▼]

The faunaʼs overexploitation in the Congo basin in general and within logging concessions in particular case still appears as a crucial problematic. Commercial poaching threats not only mammal biodiversity but also long-term food safety of local populations. Strangely, this situation is generating a new and collective answer from stakeholders having opposite interests. Administrative authorities, international NGOs of conservation, logging companies have found in the context of wood certifi cation a common deal to begin an anti-poaching action on large landscapes. This study analyses interests of each stakeholder and discusses the place given to populations in this social blending around wildlife. [less ▲]

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See detailProjective relations in a 3D environment
Billen, Roland ULg; Clementini, Eliseo

in Lecture Notes in Computer Science (2006), 4197

This paper presents a model for positional relations among bodies of arbitrary shape in three dimensions. It is based on an existing model for projective relations among regions in two dimensions. The ... [more ▼]

This paper presents a model for positional relations among bodies of arbitrary shape in three dimensions. It is based on an existing model for projective relations among regions in two dimensions. The motivation is to provide a formal qualitative spatial relations model for emerging 3D applications. Two sets of relations are defined: ternary projective relations based on the concept of collinearity between a primary object and two reference objects and quaternary projective relations based on the concept of coplanarity between a primary object and three reference objects. Four sets of JEPD relations are defined for points and bodies in R-3. [less ▲]

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See detailEn quête d’un langage scénique
Delhalle, Nancy ULg

in Alternatives Théâtrales (2006)

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