Publications ORBi OA
Bookmark and Share    
Full Text
See detailLe tremblement de terre du 18 septembre 1692 dans le nord de l'Ardenne (Belgique) : Impact sur le patrimoine architectural
Alexandre, Pierre ULg; Kusman, David; Camelbeeck, Thierry

in Levret, Agnès (Ed.) Actes des VIes Rencontres du groupe APS "Archéosismicité et Vulnérabilité. Environnement, bâti ancien et société" (Perpignan, 4-5.10.2002) (2008)

Detailed reference viewed: 81 (0 ULg)
Full Text
Peer Reviewed
See detailAvatars de la forme sonnet au XIXe siècle
Durand, Pascal ULg

in Formules (2008), 12

Detailed reference viewed: 80 (15 ULg)
Full Text
Peer Reviewed
See detailDaily activity rhythms of the African catfish Heterobranchus longifilis (Clariidae) in an experimental enclosure
Anselme, Patrick ULg; Bernaerts, Pascale; Poncin, Pascal ULg

in Aquatic Living Resources (2008), 21(4), 419-422

The swimming, air-gaping, and agonistic behaviours of Heterobranchus longifilis (318 +/- 67 mm) were examined while fish were in a fasted state under 12L: 12D and variable group size ( 2, 5, 10 and 15 ... [more ▼]

The swimming, air-gaping, and agonistic behaviours of Heterobranchus longifilis (318 +/- 67 mm) were examined while fish were in a fasted state under 12L: 12D and variable group size ( 2, 5, 10 and 15 fish) in a 1000-L aquarium. Fish exhibited a predominantly nocturnal activity pattern independent of group size. A diurnal peak of activity occurred, however, at the usual feeding time. A reduction in frequency of agonistic interactions was observed in larger groups. Five fish were then observed under 72L: 0D and 0L: 72D. The nocturnal activity pattern remained, contrary to the diurnal peak, and was independent of the duration of illumination or darkness. These results suggest the absence of biological clock in H. longifilis, although fish may somehow be influenced by past feeding experience. Behavioural plasticity in this species may provide potential for aquaculture in northern latitudes. [less ▲]

Detailed reference viewed: 67 (12 ULg)
Full Text
See detailL'Aube 1902.Une expérience architecturale et décorative de Gustave Serrurier
Folville, Xavier ULg

in Gustave Serrurier-Bovy : Acteur du futur. Exposition :Liège, Mamac, 27.09.08-18.01.09 (2008)

Étude détaillée et illustrée de la villa, pendant et après sa phase de restauration. Elle témoigne des qualités de précurseur de Gustave Serrurier, tant par son goût pour les lignes simples et les formes ... [more ▼]

Étude détaillée et illustrée de la villa, pendant et après sa phase de restauration. Elle témoigne des qualités de précurseur de Gustave Serrurier, tant par son goût pour les lignes simples et les formes géométrisées que par la façon innovante dont il distribue les espaces et les volumes intérieurs. [less ▲]

Detailed reference viewed: 20 (2 ULg)
Full Text
Peer Reviewed
See detailStimulus-response curve of human motor nerves: multicenter assessment of various indexes.
Boerio, D.; Hogrel, J.-Y.; Lefaucheur, J.-P. et al

in Neurophysiologie Clinique = Clinical Neurophysiology (2008), 38(1), 31-8

The value of various indexes to characterize the stimulus-response curve of human motor nerves was assessed in 40 healthy subjects recruited from four European centers of investigation (Creteil, Lausanne ... [more ▼]

The value of various indexes to characterize the stimulus-response curve of human motor nerves was assessed in 40 healthy subjects recruited from four European centers of investigation (Creteil, Lausanne, Liege, Marseille). Stimulus-response curves were established by stimulating the right median and ulnar motor nerves at the wrist, with stimulus durations of 0.05 and 0.5 ms. The following parameters were studied: the threshold intensity of stimulation to obtain 10% (I 10), 50% (I 50), and 90% (I 90) of the maximal compound muscle action potential, the ratios I 10/I 50, I 90/I 50, (I 90 - I 10)/I 10, (I 90-I 50)/I 50, and (I 50 - I 10)/I 10, and the slopes of the stimulus-response curves with or without normalization to I 50. For each parameter, within-center variability and reproducibility (in a test-retest study) were assessed and between-center comparisons were made. For most of the parameters, the results varied significantly within and between the centers. Within the centers, only the ratios I 10/I 50 and I 90/I 50 were found constant and reproducible. Between the centers, the absolute intensity thresholds (I 10, I 50, I 90) and the ratio I 90/I 50 did not show significant differences at stimulus duration of 0.5 ms, whatever the stimulated nerve. The reduced variability and good reproducibility of the ratios I 10/I 50 and I 90/I 50 open perspectives in neurophysiological practice for the use of these indexes of the stimulus-response curve, a rapid and noninvasive test. [less ▲]

Detailed reference viewed: 15 (2 ULg)
Full Text
Peer Reviewed
See detailLesions cerebrales demyelinisantes decouvertes chez un patient immunocompetent VIH-1+.
Nkoghe, D.; Moutschen, Michel ULg; Demonty, Jean ULg

in Médecine et Maladies Infectieuses (2008), 38(9), 500-3

We report the case of a 32-year-old immunocompetent HIV patient, presenting with acute demyelinating leukoencephalopathy. The patient displayed clinical and radiological features similar to multiple ... [more ▼]

We report the case of a 32-year-old immunocompetent HIV patient, presenting with acute demyelinating leukoencephalopathy. The patient displayed clinical and radiological features similar to multiple sclerosis. Histology revealed inflammation with necrosis, demyelination and destruction of axons. Serum tests were negative for various infectious agents as well as specific cultures and PCR. Corticotherapy and many antibiotic treatments failed. Resorption of the lesions occurred after partial excision and highly-active antiretroviral therapy (HAART). No recurrence was noted. This demyelinating cerebral disease was considered as the primary manifestation of HIV infection. HIV implication in the genesis of the process and its perpetuating this condition was suspected, but the mechanism is unclear. Dysimmune consequences related to the early course of HIV infection could be prevented by antiretroviral treatment. This study was the first description of tritherapy effectiveness on HIV related multiple sclerosis (MS)-like illness. [less ▲]

Detailed reference viewed: 44 (2 ULg)
Full Text
Peer Reviewed
See detailSubgroup and resistance analyses of raltegravir for resistant HIV-1 infection.
Cooper, David A; Steigbigel, Roy T; Gatell, Jose M et al

in New England Journal of Medicine [=NEJM] (2008), 359(4), 355-65

BACKGROUND: We evaluated the efficacy of raltegravir and the development of viral resistance in two identical trials involving patients who were infected with human immunodeficiency virus type 1 (HIV-1 ... [more ▼]

BACKGROUND: We evaluated the efficacy of raltegravir and the development of viral resistance in two identical trials involving patients who were infected with human immunodeficiency virus type 1 (HIV-1) with triple-class drug resistance and in whom antiretroviral therapy had failed. METHODS: We conducted subgroup analyses of the data from week 48 in both studies according to baseline prognostic factors. Genotyping of the integrase gene was performed in raltegravir recipients who had virologic failure. RESULTS: Virologic responses to raltegravir were consistently superior to responses to placebo, regardless of the baseline values of HIV-1 RNA level; CD4 cell count; genotypic or phenotypic sensitivity score; use or nonuse of darunavir, enfuvirtide, or both in optimized background therapy; or demographic characteristics. Among patients in the two studies combined who were using both enfuvirtide and darunavir for the first time, HIV-1 RNA levels of less than 50 copies per milliliter were achieved in 89% of raltegravir recipients and 68% of placebo recipients. HIV-1 RNA levels of less than 50 copies per milliliter were achieved in 69% and 80% of the raltegravir recipients and in 47% and 57% of the placebo recipients using either darunavir or enfuvirtide for the first time, respectively. At 48 weeks, 105 of the 462 raltegravir recipients (23%) had virologic failure. Genotyping was performed in 94 raltegravir recipients with virologic failure. Integrase mutations known to be associated with phenotypic resistance to raltegravir arose during treatment in 64 patients (68%). Forty-eight of these 64 patients (75%) had two or more resistance-associated mutations. CONCLUSIONS: When combined with an optimized background regimen in both studies, a consistently favorable treatment effect of raltegravir over placebo was shown in clinically relevant subgroups of patients, including those with baseline characteristics that typically predict a poor response to antiretroviral therapy: a high HIV-1 RNA level, low CD4 cell count, and low genotypic or phenotypic sensitivity score. (ClinicalTrials.gov numbers, NCT00293267 and NCT00293254.) [less ▲]

Detailed reference viewed: 40 (2 ULg)
Full Text
See detailMobilité scolaire et composition sociale des écoles : le cas de l'enseignement fondamental en Communauté française de Belgique
Bouchat, Thérèse - Marie; Delvaux, Bernard; Hindryckx, Geneviève ULg

in Cahiers de Recherche en Education et Formation (2008), (62),

Detailed reference viewed: 21 (3 ULg)
Full Text
See detailEspace local et choix du lieu de scolarisation dans l'enseignement fondamental : le cas de trois espaces locaux urbains en Communauté française de Belgique
Delvaux, Bernard; Bouchat, Thérèse - Marie; Hindryckx, Geneviève ULg

in Cahiers de Recherche en Education et Formation (2008), (64),

Detailed reference viewed: 27 (3 ULg)
Full Text
Peer Reviewed
See detailPhenotypic variability among patients with hyperornithinaemia-hyperammonaemia-homocitrullinuria syndrome homozygous for the delF188 mutation in SLC25A15
Debray, François-Guillaume ULg; Lambert, M.; Lemieux, M. et al

in Journal of Medical Genetics (2008), 45(11), 759-764

Detailed reference viewed: 17 (1 ULg)
Full Text
Peer Reviewed
See detailNovel causative mutations in patients with Nance-Horan syndrome and altered localization of the mutant NHS-A protein isoform
Shama, S.; Burdon, K. P.; Dave, A. et al

in Molecular Vision (2008), 14

Detailed reference viewed: 15 (0 ULg)
Full Text
Peer Reviewed
See detailReduced brain choline in homocystinuria due to remethylation defects
Debray, François-Guillaume ULg; Boulanger, Y.; Khiat, A. et al

in Neurology (2008), 71(1), 44-49

Detailed reference viewed: 19 (1 ULg)
Full Text
Peer Reviewed
See detailCobblestone-like brain dysgenesis and altered glycosylation in congenital cutis laxa. Debre type
Van Maldergem, Lionel ULg; Yuksel-Apak, M.; Kayserili, H. et al

in Neurology (2008), 71(20), 1602-1608

Detailed reference viewed: 14 (0 ULg)
Full Text
Peer Reviewed
See detailA position effect on TRPS1 us associated with Ambras syndrome in humans and the Koala phenotype in mice
Fantauzzo, K. A.; Tadin-Strapps, M.; You, Y. et al

in Human Molecular Genetics (2008)

Detailed reference viewed: 17 (1 ULg)
Full Text
Peer Reviewed
See detailPyruvate dehydrogenase deficiency presenting as intermittent isolated acute ataxia
Debray, François-Guillaume ULg; Lambert, M.; Gagne, R. et al

in Neuropediatrics (2008), 39(1), 20-23

Detailed reference viewed: 22 (2 ULg)
Full Text
Peer Reviewed
See detailAcute tubular dysfunction wtih Fanconi syndrome : a new manifestation of mitochondrial cytopathies
Debray, François-Guillaume ULg; Merouani, A.; Lambert, M. et al

in American Journal of Kidney Diseases (2008), 51(4), 691-696

Detailed reference viewed: 22 (0 ULg)
Full Text
Peer Reviewed
See detailMale-biased genes are overrepresented among novel Drosophila pseudoobscura sex-biased genes.
Metta, Muralidhar ULg; Schlotterer, Christian

in BMC Evolutionary Biology (2008), 8

BACKGROUND: The origin of functional innovation is among the key questions in biology. Recently, it has been shown that new genes could arise from non-coding DNA and that such novel genes are often ... [more ▼]

BACKGROUND: The origin of functional innovation is among the key questions in biology. Recently, it has been shown that new genes could arise from non-coding DNA and that such novel genes are often involved in male reproduction. RESULTS: With the aim of identifying novel genes, we used the technique "generation of longer cDNA fragments from serial analysis of gene expression (SAGE) tags for gene identification (GLGI)" to extend 84 sex-biased 3'end SAGE tags that previously could not be mapped to the D. pseudoobscura transcriptome. Eleven male-biased and 33 female-biased GLGI fragments were obtained, of which 5 male-biased and 3 female-biased tags corresponded to putatively novel genes. This excess of novel genes with a male-biased gene expression pattern is consistent with previous results, which found novel genes to be primarily expressed in male reproductive tissues. 5' RACE analysis indicated that these novel transcripts are very short in length and could contain introns. Interspecies comparisons revealed that most novel transcripts show evidence for purifying selection. CONCLUSION: Overall, our data indicate that among sex-biased genes a considerable number of novel genes (approximately 2-4%) exist in D. pseudoobscura, which could not be predicted based on D. melanogaster gene models. [less ▲]

Detailed reference viewed: 29 (1 ULg)
Full Text
Peer Reviewed
See detailGenetic evidence from Indian red jungle fowl corroborates multiple domestication of modern day chicken.
Kanginakudru, Sriramana; Metta, Muralidhar ULg; Jakati, R. D. et al

in BMC Evolutionary Biology (2008), 8

BACKGROUND: Domestication of chicken is believed to have occurred in Southeast Asia, especially in Indus valley. However, non-inclusion of Indian red jungle fowl (RJF), Gallus gallus murghi in previous ... [more ▼]

BACKGROUND: Domestication of chicken is believed to have occurred in Southeast Asia, especially in Indus valley. However, non-inclusion of Indian red jungle fowl (RJF), Gallus gallus murghi in previous studies has left a big gap in understanding the relationship of this major group of birds. In the present study, we addressed this issue by analyzing 76 Indian birds that included 56 G. g. murghi (RJF), 16 G. g. domesticus (domestic chicken) and 4 G. sonneratii (Grey JF) using both microsatellite markers and mitochondrial D-loop sequences. We also compared the D-loop sequences of Indian birds with those of 779 birds obtained from GenBank. RESULTS: Microsatellite marker analyses of Indian birds indicated an average FST of 0.126 within G. g. murghi, and 0.154 within G. g. domesticus while it was more than 0.2 between the two groups. The microsatellite-based phylogenetic trees showed a clear separation of G. g. domesticus from G. g. murghi, and G. sonneratii. Mitochondrial DNA based mismatch distribution analyses showed a lower Harpending's raggedness index in both G. g. murghi (0.001515) and in Indian G. g. domesticus (0.0149) birds indicating population expansion. When meta analysis of global populations of 855 birds was carried out using median joining haplotype network, 43 Indian birds of G. g. domesticus (19 haplotypes) were distributed throughout the network sharing haplotypes with the RJFs of different origins. CONCLUSION: Our results suggest that the domestication of chicken has occurred independently in different locations of Asia including India. We found evidence for domestication of Indian birds from G. g. spadiceus and G. g. gallus as well as from G. g. murghi, corroborating multiple domestication of Indian and other domestic chicken. In contrast to the commonly held view that RJF and domestic birds hybridize in nature, the present study shows that G. g. murghi is relatively pure. Further, the study also suggested that the chicken populations have undergone population expansion, especially in the Indus valley. [less ▲]

Detailed reference viewed: 45 (0 ULg)
Full Text
Peer Reviewed
See detailBluetongue virus antibodies in wild red deer in southern Belgium
Linden, Annick ULg; Mousset, B.; Grégoire, Fabien ULg et al

in Veterinary Record : Journal of the British Veterinary Association (2008)

Detailed reference viewed: 28 (4 ULg)