Publications ORBi OA
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See detailThe in-vitro antimicrobial activity of some medicinal plants against beta-lactam-resistant bacteria
Gangoue Pieboji, Joseph ULg; Eze, N.; Ngongang Djintchui, A. et al

in J Infect Dev Ctries (2009), 3(9), 671-80

BACKGROUND: In effort to identify novel bacterial agents, this study was initiated to evaluate the antimicrobial properties of 17 crude extracts from 12 medicinal plants against beta-lactam-resistant ... [more ▼]

BACKGROUND: In effort to identify novel bacterial agents, this study was initiated to evaluate the antimicrobial properties of 17 crude extracts from 12 medicinal plants against beta-lactam-resistant bacteria. METHODOLOGY: The antimicrobial activities of plant extracts were evaluated against clinically proved beta-lactam-resistant bacteria (Klebsiella pneumoniae, Klebsiella oxytoca, Enterobacter cloacae, Serratia marcescens, Acinetobacter baumannii, Staphylococcus aureus and Enterococcus sp.) and reference strains of bacteria (Escherichia coli ATCC 35218, Enterobacter aerogenes ATCC 29751, E. aerogenes ATCC 13048, Pseudomonas aeruginosa ATCC 27853 and Enterococcus hirae ATCC 9790) by using disc-diffusion and agar-dilution assays. RESULTS: The crude plant extracts demonstrated broad spectrum activity against all bacteria tested with inhibition zones in the range of 8-30 mm. The minimal inhibitory concentration (MIC) values of different plant extracts against the tested bacteria were found to range from <or= 0.3 to >or= 10 mg ml(-1). The most active plant extracts were from Dortenia picta and Bridelia micrantha (MIC: 1.25-10 mg ml(-1)) on beta-lactam-resistant Gram-negative bacilli and the extracts from B. micrantha, Mallotus oppositifolius, Garcinia lucida, Garcinia. kola, Campylospermum densiflorum (leaves) and C. zenkeri (root) on beta-lactam-resistant Gram-positive cocci (MIC: <or= 0.3-5 mg ml(-1)). CONCLUSION: Of the 17 plant extracts studied, seven showed good antimicrobial activity against the tested bacteria. The stem bark of B. micrantha and the leaves of D. picta were most active towards beta-lactamase producing Gram-negative bacilli. This study shows that medicinal plants could be sources of compounds which can be used to fight against beta-lactam resistant bacteria. [less ▲]

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See detailNouvelles courbes de productivité pour le douglas en Région wallonne
Perin, Jérôme ULg; Claessens, Hugues ULg; Hebert, Jacques ULg

in Forêt Wallonne (2009), (98), 22-28

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See detailSmall Scale Solar ORC system for distributed power
Orosz, Matthew; Mueller, Amy; Quoilin, Sylvain ULg et al

(2009)

A solar thermal organic Rankine cycle (ORC) can provide affordable energy supplies in remote regions. The advent of low-cost medium temperature parabolic trough collectors and ORC technology taking ... [more ▼]

A solar thermal organic Rankine cycle (ORC) can provide affordable energy supplies in remote regions. The advent of low-cost medium temperature parabolic trough collectors and ORC technology taking advantage of mass produced fluid machinery from HVAC industries are enabling developments for the production of small scale autonomous power generation units. Construction and testing of this type of system is discussed, including benchmarking of scrolls expanders (up to 75% isentropic effieiency) and the field testing of solar collectors (50% thermal efficiency at 150°C operating temperatures) with a nominal cost of $80 m-2. These results have led to the construction of a full-scale 3kW solar ORC power system designed to support a rural health clinic in Lesotho in southern Africa. [less ▲]

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See detailEfficacy and safety of a third anti-TNF monoclonal antibody in Crohn's disease after failure of two other anti-TNF.
Allez, Matthieu; Vermeire, Severine; Mozziconacci, Nicolas et al

in Alimentary Pharmacology & Therapeutics (2009)

Adalimumab (ADA) and certolizumab pegol (CZP) have demonstrated efficacy in Crohn's disease (CD) patients previously treated with infliximab (IFX). Aim: To assess the efficacy and tolerability of a third ... [more ▼]

Adalimumab (ADA) and certolizumab pegol (CZP) have demonstrated efficacy in Crohn's disease (CD) patients previously treated with infliximab (IFX). Aim: To assess the efficacy and tolerability of a third anti-TNF in CD after failure of and/or intolerance to two different anti-TNF. Methods: CD patients who received ADA or CZP after loss of response and/or intolerance to two anti-TNF were included in this retrospective study. Data were collected using a standardized questionnaire. Clinical response, duration, safety and reasons for discontinuation were assessed. Results: Sixty-seven patients treated with CZP (n=40) or ADA (n=27) were included. A clinical response was observed in 41 (61%) at week 6 and 34 patients (51%) at week 20. The probability of remaining under treatment at 3 months, 6 months and 9 months was 68%, 60% and 45%, respectively. At the end of follow-up, the third anti-TNF had been stopped in 36 patients for intolerance (n=13), or failure (n=23). Two deaths were observed. Conclusion: Treatment, with a third anti-TNF (CZP or ADA) agent, of CD patients who have experienced loss of response and/or intolerance to two anti-TNF antibodies, has favorable short- and long-term efficacy and is an option to be considered in patients with no other therapeutic options. [less ▲]

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See detailProtéomique par SELDI-TOF-MS des maladies inflammatoires articulaires: identification des protéines S100 comme protéines d'intérêt
De Seny, Dominique ULg; Ribbens, Clio ULg; Cobraiville, Gaël ULg et al

in Revue Médicale de Liège (2009), 64(Spec No), 29-35

Clinical proteomics is a technical approach studying the entire proteome expressed by cells, tissues or organs. It describes the dynamics of cell regulation by detecting molecular events related to ... [more ▼]

Clinical proteomics is a technical approach studying the entire proteome expressed by cells, tissues or organs. It describes the dynamics of cell regulation by detecting molecular events related to diseases development. Proteomic techniques focus mainly on identification of new biomarkers or new therapeutic targets. It is a multidisciplinary approach using medical, biological, bioanalytical and bioinformatics knowledges. A strong collaboration between these fields allowed SELDI-TOF-MS proteomics studies to be performed at the CHU and the University of Liege, in GIGA-Research facilities. The aim of these studies was driven along three main axes of research related to the identification of biomarkers specific to a studied pathology, to a common biological pathway and, finally, to a treatment response. [less ▲]

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See detailValorisation du douglas en bois de struture et bardages : impact de la vitesse de croissance des arbres
Henin, Jean-Marc; Pollet, Caroline; Hebert, Jacques ULg et al

in Forêt Wallonne (2009), (98), 29-38

Jusqu’à présent, la gestion du douglas était plus ou moins calquée sur celle de l’épicéa, ce qui impliquait une sous-exploitation du potentiel. La recherche présentée a pour but d’évaluer l’impact de la ... [more ▼]

Jusqu’à présent, la gestion du douglas était plus ou moins calquée sur celle de l’épicéa, ce qui impliquait une sous-exploitation du potentiel. La recherche présentée a pour but d’évaluer l’impact de la vitesse de croissance sur les caractéristiques du matériau produit et donc l’impact de la sylviculture opérée sur le douglas. <br /> <br />Soixante-six arbres ont été choisis dans onze peuplements. Six arbres par peuplement : deux dominants, deux co-dominants, deux dominés. L’âge des peuplements se situe entre 40 et 70 ans. Les peuplements les plus jeunes ont suivi les scénarios sylvicoles les plus dynamiques, les peuplements les plus vieux ont été soumis aux pratiques les plus conservatrices. <br /> <br />Sur base d’un classement visuel, 85 % des bois de structure et 77 % des lames de bardage débitées sont valorisables. Ces débits sont représentatifs de plus de 75 % du volume marchand des arbres. Le constat est donc positif. <br /> <br />La maximisation de la croissance du douglas n’est pas la solution qui permet une valorisation optimale de la ressource par le secteur de la première transformation, en raison de l’augmentation de la nodosité avec la vitesse de croissance. Par contre, la largeur moyenne des cernes mesurée sur les sciages n’est pas en soi un facteur pénalisant pour le classement visuel. <br /> <br />Dans un contexte de classement visuel, la recherche de vitesses de croissance relativement élevées semble subordonnée à la pratique d’un élagage qui permettra de pallier la forte branchaison. Il reste à évaluer si la plus-value apportée par l’élagage compense la perte de qualité engendrée par l’augmentation de la taille des nœuds au-delà de la partie élaguée, quand on sait que pour 6 mètres élagués, 65 % du volume des arbres du peuplement final ne le sont pas. [less ▲]

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See detailDistribution and evolution of ferripyoverdine receptors in Pseudomonas aeruginosa.
Bodilis, Josselin; Ghysels, Bart ULg; Osayande, Julie et al

in Environmental microbiology (2009), 11(8), 2123-35

Pseudomonas aeruginosa is a ubiquitous gram-negative bacterium, which is also able to cause severe opportunistic infections in humans. The colonization of the host is importantly affected by the ... [more ▼]

Pseudomonas aeruginosa is a ubiquitous gram-negative bacterium, which is also able to cause severe opportunistic infections in humans. The colonization of the host is importantly affected by the production of the high-affinity iron (III) scavenging peptidic siderophore pyoverdine. The species P. aeruginosa can be divided into three subgroups ('siderovars'), each characterized by the production of a specific pyoverdine and receptor (FpvA). We used a multiplex PCR to determine the FpvA siderovar on 345 P. aeruginosa strains from environmental or clinical origin. We found about the same proportion of each type in clinical strains, while FpvA type I was slightly over-represented (49%) in environmental strains. Our multiplex PCR also detected the presence or absence of an additional receptor for type I pyoverdine (FpvB). The fpvB gene was in fact present in the vast majority of P. aeruginosa strains (93%), regardless of their siderovar or their origin. Finally, molecular analyses of fpvA and fpvB genes highlighted a complex evolutionary history, probably linked to the central role of iron acquisition in the ecology and virulence of P. aeruginosa. [less ▲]

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See detailFirst epidemiological study on exposure to Neospora caninum in different canine populations in the Algiers District (Algeria)
Ghalmi, F.; China, B.; Kaïdi, R. et al

in Parasitology International (2009), 58(4), 444-450

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See detailCarnet du Louvre
Havelange, Carl ULg

in Cahiers Internationaux de Symbolisme (2009), 122-123-124

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See detailDévelopper les compétences métacognitives en lecture: une piste pour accompagner les lecteurs en difficulté au début du secondaire
De Croix, Séverine ULg; Ledur, Dominique

in Coupremanne, Michel (Ed.) Les dynamiques des apprentissages: la continuité au coeur de nos pratiques de 2ans 1/2 à 14 ans (2009)

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See detailA rare case of placental choriangioma associated with neonatal diffuse hemangomatosis.
Capelle, Xavier ULg; Syrios, Petros ULg; Chantraine, Frédéric ULg et al

in Journal de Gynécologie, Obstétrique et Biologie de la Reproduction (2009), 38(3), 246-249

Placental chorioangioma is a benign vascular tumor. Lesions larger than 4cm may cause fetal and maternal complications. Its association with disseminated neonatal hemangiomatosis is rarely described. We ... [more ▼]

Placental chorioangioma is a benign vascular tumor. Lesions larger than 4cm may cause fetal and maternal complications. Its association with disseminated neonatal hemangiomatosis is rarely described. We report a case of a large chorioangioma associated with an hydrops foetalis and disseminated neonatal hemangiomatosis. The relationship between placental chorioangioma and hemangioma is briefly discussed. [less ▲]

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See detailDetecting consciousness in a total Locked-in syndrome: an active event related paradigm
Schnakers, Caroline ULg; Perrin, Fabien; Schabus, Manuel et al

in Neurocase : Case Studies in Neuropsychology, Neuropsychiatry & Behavioural Neurology (2009), 25

Total locked-in syndrome is characterized by tetraplegia, anarthria and paralysis of eye motility. In this study, consciousness was detected in a 21-year-old woman who presented a total locked-in syndrome ... [more ▼]

Total locked-in syndrome is characterized by tetraplegia, anarthria and paralysis of eye motility. In this study, consciousness was detected in a 21-year-old woman who presented a total locked-in syndrome after a basilar artery thrombosis (49 days post-injury) using an active event-related paradigm. The patient was presented sequences of names containing the patient's own name and other names. The patient was instructed to count her own name or to count another target name. Similar to 4 age- and gender-matched healthy controls, the P3 response recorded for the voluntarily counted own name was larger than while passively listening. This P3 response was observed 14 days before the first behavioral signs of consciousness. This study shows that our active event-related paradigm allowed to identify voluntary brain activity in a patient who would behaviorally be diagnosed as comatose. [less ▲]

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See detailType-1.5 Superconductivity
Moshchalkov, Victor; Menghini, Mariela; Nishio, T. et al

in Physical Review Letters (2009), 102(11),

We demonstrate the existence of a novel superconducting state in high quality two-component MgB(2) single crystalline superconductors where a unique combination of both type-1 (lambda(1)/xi(1)< 1/2) and ... [more ▼]

We demonstrate the existence of a novel superconducting state in high quality two-component MgB(2) single crystalline superconductors where a unique combination of both type-1 (lambda(1)/xi(1)< 1/2) and type-2 (lambda(2)/xi(2)> 1/2) superconductor conditions is realized for the two components of the order parameter. This condition leads to a vortex-vortex interaction attractive at long distances and repulsive at short distances, which stabilizes unconventional stripe- and gossamerlike vortex patterns that we have visualized in this type-1.5 superconductor using Bitter decoration and also reproduced in numerical simulations. [less ▲]

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See detailLa vignette thérapeutique de l'étudiant. La maladie de Parkinson debutante
DELVAUX, Valérie ULg; MOONEN, Gustave ULg; Garraux, Gaëtan ULg

in Revue Médicale de Liège (2009), 64(4), 228-32

We present a discussion on the treatment options in the case of a patient seen at the outpatient abnormal movement clinic for a resting tremor of both hands. Signs and symptoms of the parkinsonian ... [more ▼]

We present a discussion on the treatment options in the case of a patient seen at the outpatient abnormal movement clinic for a resting tremor of both hands. Signs and symptoms of the parkinsonian syndrome are summarized as well as the current treatment options of early Parkinson's disease. [less ▲]

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See detailEntropy of entanglement and multifractal exponents for random states
Giraud, O.; Martin, John ULg; Georgeot, B.

in Physical Review. A (2009), 79

We relate the entropy of entanglement of ensembles of random vectors to their generalized fractal dimensions. Expanding the von Neumann entropy around its maximum we show that the first order only depends ... [more ▼]

We relate the entropy of entanglement of ensembles of random vectors to their generalized fractal dimensions. Expanding the von Neumann entropy around its maximum we show that the first order only depends on the participation ratio, while higher orders involve other multifractal exponents. These results can be applied to entanglement behavior near the Anderson transition. [less ▲]

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See detailTraitement de la prééclampsie sévère: jusqu'où, et pour quels risques/bénéfices?
PETIT, Philippe ULg; Top, Marlene; CHANTRAINE, Frédéric ULg et al

in Revue Médicale de Liège (2009), 64(12), 620-625

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See detailMécanismes de l'anesthésie générale: apport de l'imagerie fonctionnelle
Boveroux, Pierre ULg; Bonhomme, Vincent ULg; Kirsch, Murielle ULg et al

in Revue Médicale de Liège (2009), 64(Synthèse 2009), 36-41

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